Theodora (Dora) Manolakou

Om mig
Publikationer
Populärvetenskap och samverkan

Forskningsbeskrivning

I focus on the role and pharmaceutical targeting of the DNA damage response (DDR) and metabolism in Autoimmunity.

Artiklar

Article: ANNALS OF THE RHEUMATIC DISEASES. 2024;83(9):1132-1143
Disentangling the riddle of systemic lupus erythematosus with antiphospholipid syndrome: blood transcriptome analysis reveals a less-pronounced IFN-signature and distinct molecular profiles in venous versus arterial events
Nikolopoulos D; Loukogiannaki C; Sentis G; Garantziotis P; Manolakou T; Kapsala N; Nikoloudaki M; Pieta A; Flouda S; Parodis I; Bertsias G; Fanouriakis A; Filia A; Boumpas DT
Journal article: ONCOGENESIS. 2024;13(1):17
Mitotic MTH1 inhibitor TH1579 induces PD-L1 expression and inflammatory response through the cGAS-STING pathway
Shen J; Mancina EG; Chen S; Manolakou T; Gad H; Berglund UW; Sanjiv K; Helleday T
Article: LUPUS. 2024;33(2):166-171
Impaired serotonin synthesis in hippocampus of murine lupus represents an early neuropsychiatric event
Nikolopoulos D; Nakos-Bimpos M; Manolakou T; Polissidis A; Boumpas DT
Article: CLINICAL IMMUNOLOGY. 2023;255:109765
Transcriptomic and proteomic profiling reveals distinct pathogenic features of peripheral non-classical monocytes in systemic lupus erythematosus.
Stergioti EM; Manolakou T; Sentis G; Samiotaki M; Kapsala N; Fanouriakis A; Boumpas DT; Banos A
Article: ANNALS OF THE RHEUMATIC DISEASES. 2023;82(5):646-657
Microglia activation in the presence of intact blood-brain barrier and disruption of hippocampal neurogenesis via IL-6 and IL-18 mediate early diffuse neuropsychiatric lupus
Nikolopoulos D; Manolakou T; Polissidis A; Filia A; Bertsias G; Koutmani Y; Boumpas DT
Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2023;27(9):1192-1205
Down-regulation of human long non-coding RNA LINC01187 is associated with nephropathies
Manolakou T; Kaltezioti V; Prakoura N; Kavvadas P; Reichelt-Wurm S; Gakiopoulou H; Banas M; Banas B; Lindenmeyer MT; Cohen CD; Boor P; Djudjaj S; Boumpas DT; Chatziantoniou C; Charonis A; Politis PK
Article: NPJ REGENERATIVE MEDICINE. 2023;8(1):13
Return of the Tbx5; lineage-tracing reveals ventricular cardiomyocyte-like precursors in the injured adult mammalian heart
Siatra P; Vatsellas G; Chatzianastasiou A; Balafas E; Manolakou T; Papapetropoulos A; Agapaki A; Mouchtouri E-T; Ruchaya PJ; Korovesi AG; Mavroidis M; Thanos D; Beis D; Kokkinopoulos I
Article: FRONTIERS IN IMMUNOLOGY. 2023;14:1203848
A network-based approach reveals long non-coding RNAs associated with disease activity in lupus nephritis: key pathways for flare and potential biomarkers to be used as liquid biopsies
Sentis G; Loukogiannaki C; Malissovas N; Nikolopoulos D; Manolakou T; Flouda S; Grigoriou M; Banos A; Boumpas DTT; Filia A
Article: SCIENCE ADVANCES. 2022;8(43):eabo5840
ATR-mediated DNA damage responses underlie aberrant B cell activity in systemic lupus erythematosus
Manolakou T; Nikolopoulos D; Gkikas D; Filia A; Samiotaki M; Stamatakis G; Fanouriakis A; Politis P; Banos A; Alissafi T; Verginis P; Boumpas DT
Article: ANNALS OF THE RHEUMATIC DISEASES. 2022;81(10):1409-1419
Cross-species transcriptome analysis for early detection and specific therapeutic targeting of human lupus nephritis
Frangou E; Garantziotis P; Grigoriou M; Banos A; Nikolopoulos D; Pieta A; Doumas SA; Fanouriakis A; Hatzioannou A; Manolakou T; Alissafi T; Verginis P; Athanasiadis E; Dermitzakis E; Bertsias G; Filia A; Boumpas DT
Article: STEM CELLS. 2022;40(7):678-690
The Neurodevelopmental Disorders Associated Gene Rnf113a Regulates Survival and Differentiation Properties of Neural Stem Cells
Tsampoula M; Tarampoulous I; Manolakou T; Ninou E; Politis PK
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(39):e2015243118
Nuclear receptor NR5A2 negatively regulates cell proliferation and tumor growth in nervous system malignancies
Gkikas D; Stellas D; Polissidis A; Manolakou T; Kokotou MG; Kokotos G; Politis PK
Article: SCIENTIFIC REPORTS. 2021;11(1):15759
Patrolling human SLE haematopoietic progenitors demonstrate enhanced extramedullary colonisation; implications for peripheral tissue injury
Kokkinopoulos I; Banos A; Grigoriou M; Filia A; Manolakou T; Alissafi T; Malissovas N; Mitroulis I; Verginis P; Boumpas DT

Alla övriga publikationer

Conference publication: 2024;:23.2-2324
OP0139 THE MOLECULAR LANDSCAPE OF ANTIPHOSPHOLIPID SYNDROME IN SYSTEMIC LUPUS ERYTHEMATOSUS: DISTINCT TRANSCRIPTIONAL PROFILES IN VENOUS VERSUS ARTERIAL EVENTS, WITH POTENTIAL THERAPEUTIC IMPLICATIONS
Nikolopoulos D; Loukogiannaki C; Sentis G; Garantziotis P; Manolakou T; Kapsala N; Nikoloudaki M; Pieta A; Flouda S; Parodis I; Bertsias GK; Fanouriakis A; Filia A; Boumpas D
Review: BIOMEDICINES. 2022;10(11):2820
Antiviral Innate Immune Responses in Autoimmunity: Receptors, Pathways, and Therapeutic Targeting
Stergioti EM; Manolakou T; Boumpas DT; Banos A
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2022;81:484.1-484
DISRUPTED HIPPOCAMPAL NEUROGENESIS MEDIATED BY IL-6 AND IL-18 INDUCE NEUROPSYCHIATRIC CHANGES IN MURINE LUPUS
Nikolopoulos D; Manolakou T; Polissidis A; Filia A; Koutmani Y; Boumpas D
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2021;80:439.2-440
COMBINED ANALYSIS OF METABOLIC AND TRANSCRIPTOMIC KIDNEY PROFILES OF NZW/B-F1 MURINE LUPUS UNCOVERS BIOLOGICAL MECHANISMS PRECEDING THE ONSET OF NEPHRITIS
Manolakou T; Tsiara I; Nikolopoulos D; Garantziotis P; Benaki D; Gikas E; Frangou E; Mikroa E; Boumpas D
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2021;80:21.1-22
HIPPOCAMPAL IMMUNE CELL TRAFFICKING AND A MYELOID PREDOMINANT INFLAMMATORY RESPONSE WITH ENHANCED ANTIGEN PRESENTATION AND DECREASED LEVELS OF NEUROTRANSMITTERS UNDERLY THE NEUROPSYCHIATRIC PHENOTYPE OF THE NZW/NZB MURINE LUPUS MODEL
Nikolopoulos D; Manolakou T; Filia A; Nakos-Bimpos M; Polissidis A; Boumpas D
Review: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(11):5842
DNA Damage Response in the Adaptive Arm of the Immune System: Implications for Autoimmunity
Manolakou T; Verginis P; Boumpas DT

Forskningsbeskrivning

Artiklar

Alla övriga publikationer

Nyheter från KI

Kalenderhändelser från KI