Theodora (Dora) Manolakou

About me
Publications
Public outreach and news

About me

PhD in Molecular Medicine and Immunology with focus on autoimmune diseases, BRFAA, Athens, Greece
MSc in Molecular Biomedicine, Medical School, NKUA, Athens, Greece
BSc/MSc (integrated) in Biotechnology, School of Applied Biology and Biotechnology, AUA, Athens, Greece

Research

DNA damage response signalling, Metabolism and Autoimmune diseases

Articles

Article: ANNALS OF THE RHEUMATIC DISEASES. 2024;83(9):1132-1143
Disentangling the riddle of systemic lupus erythematosus with antiphospholipid syndrome: blood transcriptome analysis reveals a less-pronounced IFN-signature and distinct molecular profiles in venous versus arterial events
Nikolopoulos D; Loukogiannaki C; Sentis G; Garantziotis P; Manolakou T; Kapsala N; Nikoloudaki M; Pieta A; Flouda S; Parodis I; Bertsias G; Fanouriakis A; Filia A; Boumpas DT
Journal article: ONCOGENESIS. 2024;13(1):17
Mitotic MTH1 inhibitor TH1579 induces PD-L1 expression and inflammatory response through the cGAS-STING pathway
Shen J; Mancina EG; Chen S; Manolakou T; Gad H; Berglund UW; Sanjiv K; Helleday T
Article: LUPUS. 2024;33(2):166-171
Impaired serotonin synthesis in hippocampus of murine lupus represents an early neuropsychiatric event
Nikolopoulos D; Nakos-Bimpos M; Manolakou T; Polissidis A; Boumpas DT
Article: CLINICAL IMMUNOLOGY. 2023;255:109765
Transcriptomic and proteomic profiling reveals distinct pathogenic features of peripheral non-classical monocytes in systemic lupus erythematosus.
Stergioti EM; Manolakou T; Sentis G; Samiotaki M; Kapsala N; Fanouriakis A; Boumpas DT; Banos A
Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2023;27(9):1192-1205
Down-regulation of human long non-coding RNA LINC01187 is associated with nephropathies
Manolakou T; Kaltezioti V; Prakoura N; Kavvadas P; Reichelt-Wurm S; Gakiopoulou H; Banas M; Banas B; Lindenmeyer MT; Cohen CD; Boor P; Djudjaj S; Boumpas DT; Chatziantoniou C; Charonis A; Politis PK
Article: ANNALS OF THE RHEUMATIC DISEASES. 2023;82(5):646-657
Microglia activation in the presence of intact blood-brain barrier and disruption of hippocampal neurogenesis via IL-6 and IL-18 mediate early diffuse neuropsychiatric lupus
Nikolopoulos D; Manolakou T; Polissidis A; Filia A; Bertsias G; Koutmani Y; Boumpas DT
Article: NPJ REGENERATIVE MEDICINE. 2023;8(1):13
Return of the Tbx5; lineage-tracing reveals ventricular cardiomyocyte-like precursors in the injured adult mammalian heart
Siatra P; Vatsellas G; Chatzianastasiou A; Balafas E; Manolakou T; Papapetropoulos A; Agapaki A; Mouchtouri E-T; Ruchaya PJ; Korovesi AG; Mavroidis M; Thanos D; Beis D; Kokkinopoulos I
Article: FRONTIERS IN IMMUNOLOGY. 2023;14:1203848
A network-based approach reveals long non-coding RNAs associated with disease activity in lupus nephritis: key pathways for flare and potential biomarkers to be used as liquid biopsies
Sentis G; Loukogiannaki C; Malissovas N; Nikolopoulos D; Manolakou T; Flouda S; Grigoriou M; Banos A; Boumpas DTT; Filia A
Article: SCIENCE ADVANCES. 2022;8(43):eabo5840
ATR-mediated DNA damage responses underlie aberrant B cell activity in systemic lupus erythematosus
Manolakou T; Nikolopoulos D; Gkikas D; Filia A; Samiotaki M; Stamatakis G; Fanouriakis A; Politis P; Banos A; Alissafi T; Verginis P; Boumpas DT
Article: ANNALS OF THE RHEUMATIC DISEASES. 2022;81(10):1409-1419
Cross-species transcriptome analysis for early detection and specific therapeutic targeting of human lupus nephritis
Frangou E; Garantziotis P; Grigoriou M; Banos A; Nikolopoulos D; Pieta A; Doumas SA; Fanouriakis A; Hatzioannou A; Manolakou T; Alissafi T; Verginis P; Athanasiadis E; Dermitzakis E; Bertsias G; Filia A; Boumpas DT
Article: STEM CELLS. 2022;40(7):678-690
The Neurodevelopmental Disorders Associated Gene Rnf113a Regulates Survival and Differentiation Properties of Neural Stem Cells
Tsampoula M; Tarampoulous I; Manolakou T; Ninou E; Politis PK
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(39):e2015243118
Nuclear receptor NR5A2 negatively regulates cell proliferation and tumor growth in nervous system malignancies
Gkikas D; Stellas D; Polissidis A; Manolakou T; Kokotou MG; Kokotos G; Politis PK
Article: SCIENTIFIC REPORTS. 2021;11(1):15759
Patrolling human SLE haematopoietic progenitors demonstrate enhanced extramedullary colonisation; implications for peripheral tissue injury
Kokkinopoulos I; Banos A; Grigoriou M; Filia A; Manolakou T; Alissafi T; Malissovas N; Mitroulis I; Verginis P; Boumpas DT

All other publications

Review: BIOMEDICINES. 2022;10(11):2820
Antiviral Innate Immune Responses in Autoimmunity: Receptors, Pathways, and Therapeutic Targeting
Stergioti EM; Manolakou T; Boumpas DT; Banos A
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2022;81:484.1-48484
DISRUPTED HIPPOCAMPAL NEUROGENESIS MEDIATED BY IL-6 AND IL-18 INDUCE NEUROPSYCHIATRIC CHANGES IN MURINE LUPUS
Nikolopoulos D; Manolakou T; Polissidis A; Filia A; Koutmani Y; Boumpas D
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2021;80:439.2-43440
COMBINED ANALYSIS OF METABOLIC AND TRANSCRIPTOMIC KIDNEY PROFILES OF NZW/B-F1 MURINE LUPUS UNCOVERS BIOLOGICAL MECHANISMS PRECEDING THE ONSET OF NEPHRITIS
Manolakou T; Tsiara I; Nikolopoulos D; Garantziotis P; Benaki D; Gikas E; Frangou E; Mikroa E; Boumpas D
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2021;80:21.1-2122
HIPPOCAMPAL IMMUNE CELL TRAFFICKING AND A MYELOID PREDOMINANT INFLAMMATORY RESPONSE WITH ENHANCED ANTIGEN PRESENTATION AND DECREASED LEVELS OF NEUROTRANSMITTERS UNDERLY THE NEUROPSYCHIATRIC PHENOTYPE OF THE NZW/NZB MURINE LUPUS MODEL
Nikolopoulos D; Manolakou T; Filia A; Nakos-Bimpos M; Polissidis A; Boumpas D
Review: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(11):5842
DNA Damage Response in the Adaptive Arm of the Immune System: Implications for Autoimmunity
Manolakou T; Verginis P; Boumpas DT

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