Theodora (Dora) Manolakou

About me
Publications
Public outreach and news

About me

PhD in Molecular Medicine and Immunology with focus on autoimmune diseases, BRFAA, Athens, Greece
MSc in Molecular Biomedicine, Medical School, NKUA, Athens, Greece
BSc/MSc (integrated) in Biotechnology, School of Applied Biology and Biotechnology, AUA, Athens, Greece

Research

DNA damage response signalling, Metabolism and Autoimmune diseases

Articles

Journal article: ANNALS OF THE RHEUMATIC DISEASES. 2024;:ard-2024-225664

Disentangling the riddle of systemic lupus erythematosus with antiphospholipid syndrome: blood transcriptome analysis reveals a less-pronounced IFN-signature and distinct molecular profiles in venous versus arterial events.

Nikolopoulos D; Loukogiannaki C; Sentis G; Garantziotis P; Manolakou T; Kapsala N; Nikoloudaki M; Pieta A; Flouda S; Parodis I; Bertsias G; Fanouriakis A; Filia A; Boumpas DT
Journal article: LUPUS. 2024;33(2):166-171

Impaired serotonin synthesis in hippocampus of murine lupus represents an early neuropsychiatric event.

Nikolopoulos D; Nakos-Bimpos M; Manolakou T; Polissidis A; Boumpas DT
Journal article: CLINICAL IMMUNOLOGY. 2023;255:109765

Transcriptomic and proteomic profiling reveals distinct pathogenic features of peripheral non-classical monocytes in systemic lupus erythematosus.

Stergioti EM; Manolakou T; Sentis G; Samiotaki M; Kapsala N; Fanouriakis A; Boumpas DT; Banos A
Article: ANNALS OF THE RHEUMATIC DISEASES. 2023;82(5):646-657

Microglia activation in the presence of intact blood-brain barrier and disruption of hippocampal neurogenesis via IL-6 and IL-18 mediate early diffuse neuropsychiatric lupus.

Nikolopoulos D; Manolakou T; Polissidis A; Filia A; Bertsias G; Koutmani Y; Boumpas DT
Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2023;27(9):1192-1205

Down-regulation of human long non-coding RNA LINC01187 is associated with nephropathies.

Manolakou T; Kaltezioti V; Prakoura N; Kavvadas P; Reichelt-Wurm S; Gakiopoulou H; Banas M; Banas B; Lindenmeyer MT; Cohen CD; Boor P; Djudjaj S; Boumpas DT; Chatziantoniou C; Charonis A; Politis PK
Article: NPJ REGENERATIVE MEDICINE. 2023;8(1):13

Return of the Tbx5; lineage-tracing reveals ventricular cardiomyocyte-like precursors in the injured adult mammalian heart.

Siatra P; Vatsellas G; Chatzianastasiou A; Balafas E; Manolakou T; Papapetropoulos A; Agapaki A; Mouchtouri E-T; Ruchaya PJ; Korovesi AG; Mavroidis M; Thanos D; Beis D; Kokkinopoulos I
Journal article: FRONTIERS IN IMMUNOLOGY. 2023;14:1203848

A network-based approach reveals long non-coding RNAs associated with disease activity in lupus nephritis: key pathways for flare and potential biomarkers to be used as liquid biopsies.

Sentis G; Loukogiannaki C; Malissovas N; Nikolopoulos D; Manolakou T; Flouda S; Grigoriou M; Banos A; Boumpas DT; Filia A
Article: SCIENCE ADVANCES. 2022;8(43):eabo5840

ATR-mediated DNA damage responses underlie aberrant B cell activity in systemic lupus erythematosus.

Manolakou T; Nikolopoulos D; Gkikas D; Filia A; Samiotaki M; Stamatakis G; Fanouriakis A; Politis P; Banos A; Alissafi T; Verginis P; Boumpas DT
Article: ANNALS OF THE RHEUMATIC DISEASES. 2022;81(10):1409-1419

Cross-species transcriptome analysis for early detection and specific therapeutic targeting of human lupus nephritis.

Frangou E; Garantziotis P; Grigoriou M; Banos A; Nikolopoulos D; Pieta A; Doumas SA; Fanouriakis A; Hatzioannou A; Manolakou T; Alissafi T; Verginis P; Athanasiadis E; Dermitzakis E; Bertsias G; Filia A; Boumpas DT
Article: STEM CELLS. 2022;40(7):678-690

The Neurodevelopmental Disorders Associated Gene Rnf113a Regulates Survival and Differentiation Properties of Neural Stem Cells.

Tsampoula M; Tarampoulous I; Manolakou T; Ninou E; Politis PK
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(39):e2015243118

Nuclear receptor NR5A2 negatively regulates cell proliferation and tumor growth in nervous system malignancies.

Gkikas D; Stellas D; Polissidis A; Manolakou T; Kokotou MG; Kokotos G; Politis PK
Article: SCIENTIFIC REPORTS. 2021;11(1):15759

Patrolling human SLE haematopoietic progenitors demonstrate enhanced extramedullary colonisation; implications for peripheral tissue injury.

Kokkinopoulos I; Banos A; Grigoriou M; Filia A; Manolakou T; Alissafi T; Malissovas N; Mitroulis I; Verginis P; Boumpas DT

All other publications

Review: BIOMEDICINES. 2022;10(11):2820

Antiviral Innate Immune Responses in Autoimmunity: Receptors, Pathways, and Therapeutic Targeting.

Stergioti EM; Manolakou T; Boumpas DT; Banos A
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2022;81:484.1-484

DISRUPTED HIPPOCAMPAL NEUROGENESIS MEDIATED BY IL-6 AND IL-18 INDUCE NEUROPSYCHIATRIC CHANGES IN MURINE LUPUS

Nikolopoulos D; Manolakou T; Polissidis A; Filia A; Koutmani Y; Boumpas D
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2021;80:439.2-440

COMBINED ANALYSIS OF METABOLIC AND TRANSCRIPTOMIC KIDNEY PROFILES OF NZW/B-F1 MURINE LUPUS UNCOVERS BIOLOGICAL MECHANISMS PRECEDING THE ONSET OF NEPHRITIS

Manolakou T; Tsiara I; Nikolopoulos D; Garantziotis P; Benaki D; Gikas E; Frangou E; Mikroa E; Boumpas D
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2021;80:21.1-22

HIPPOCAMPAL IMMUNE CELL TRAFFICKING AND A MYELOID PREDOMINANT INFLAMMATORY RESPONSE WITH ENHANCED ANTIGEN PRESENTATION AND DECREASED LEVELS OF NEUROTRANSMITTERS UNDERLY THE NEUROPSYCHIATRIC PHENOTYPE OF THE NZW/NZB MURINE LUPUS MODEL

Nikolopoulos D; Manolakou T; Filia A; Nakos-Bimpos M; Polissidis A; Boumpas D
Review: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(11):5842

DNA Damage Response in the Adaptive Arm of the Immune System: Implications for Autoimmunity.

Manolakou T; Verginis P; Boumpas DT

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