Shuai Yuan

Om mig
Publikationer
Forskningsbidrag
CV
Populärvetenskap och samverkan

Om mig

Jag arbetar på enheten för kardiovaskulär och näringsepidemiologi, Institutet för miljömedicin vid Karolinska Institutet. Jag är intresserad av att undersöka sambanden mellan livsstilsfaktorer och nutrition med kardiometabola och gastrointestinala sjukdomar genom att använda epidemiologiska och genetiska metoder.

Forskningsbeskrivning

• Undersöka sambanden mellan livsstil och näringsfaktorer med kardiometabola och gastrointestinala sjukdomar.
• Identifiera proteinbiomarkörer och läkemedelsmål för vanliga sjukdomar genom att integrera humant plasmaproteom med genomet.
• Genomomfattande associationsanalys och efterföljande genetisk analys av kardiometabola och gastrointestinala sjukdomar.

Artiklar

Journal article: DIABETES OBESITY & METABOLISM. 2026;28(6):5029-5042
Proteomic Profiling of Plasma to Uncover Novel Intervention Targets and Prognostic Biomarkers for Chronic Liver Diseases
Li X; Sun J; Zhao J; Jiang F; Zhang M; Wu H; Yuan S; Li X; Lu J; Mantzoros CS
Article: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2026;:S1538-7836(26)00269-2
Incident venous thromboembolism in biopsy-proven metabolic dysfunction-associated steatotic liver disease: a nationwide cohort study.
Yuan S; Ebrahimi F; Forss A; Sun J; Zöller B; Hagström H; Ludvigsson JF
Journal article: NATURE GENETICS. 2026;58(5):1186
Challenges and future directions for Mendelian randomization (APR, 10.1038/s41588-026-02546-6, 2026)
Sanderson E; Levin MG; Walker V; Yuan S; Badini I; Dolce J; Mahida KJ; Nho J-W; Pingault J-B; Damrauer SM; Hemani G; Davies NM
Journal article: NATURE GENETICS. 2026;58(5):984-994
Challenges and future directions for Mendelian randomization
Sanderson E; Levin MG; Walker V; Yuan S; Badini I; Dolce J; Mahida KJ; Nho J-W; Pingault J; Damrauer SM; Hemani G; Davies NM
Journal article: JCI INSIGHT. 2026;:e200198
Endothelial GDF15 deficiency enhances barrier function and mitigates pulmonary fibrosis.
Raffensperger K; Bueno M; Philips BJ; Miller M; Katona M; Yuan S; Estrada-Bernal A; Chuan B; Suresh P; Taiclet S; Hahn S; Zhang Y; Alder JK; Nouraie SM; Kass DJ; Eickelberg O; Straub AC
Article: JOURNAL OF NUTRITION HEALTH & AGING. 2026;30(6):100848
Dietary total antioxidant capacity alleviates inflammatory bowel disease-related surgery, gastrointestinal cancer, and mortality risks among middle-aged and older individuals
Fu T; Dan L; Wang S; Wu X; Sun J; Yuan S; Wolk A; Ludvigsson JF; Wang X; Larsson SC; Chen J; Li X
Article: JOURNAL OF ADVANCED RESEARCH. 2026;:S2090-1232(26)00293-6
Antidiabetic drug effects on gastrointestinal health: convergent evidence from a longitudinal cohort and Mendelian randomization study.
Li X; Chen J; Wang L; Jiang F; Ruan X; Yuan S; Zheng J; Gill D; Larsson SC; Mantzoros CS; Li X
Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY. 2026;41(3):367-375
Incidence and prevalence of autoimmune disease in the Swedish National Patient Register
Bergman D; Sundquist K; Segelmark M; Svedbom A; Sun J; Piehl F; Yuan S; Kampe O; Brodin P; Ebrahimi F; Askling J; Ludvigsson JF
Journal article: JACC-BASIC TO TRANSLATIONAL SCIENCE. 2026;11(2):101457
Lipoprotein(a) Is Associated With Increased Risk of Abdominal Aortic Aneurysm.
Sharma P; Judy R; Yuan S; Gellatly C; Saxby KL; Rader DJ; Bown MJ; Levin MG; Damrauer SM
Article: THERAPEUTIC ADVANCES IN GASTROENTEROLOGY. 2026;19:17562848261424145
Association of inflammatory bowel disease with cardiovascular disease, and the mediating role of inflammation: a matched-cohort study
Geng J; Chen J; Olen O; Halfvarson J; Sundstrom J; Yuan S; Ludvigsson JF; Sun J
Journal article: MEDRXIV. 2025;:2025.12.16.25341932
A sparse proteomic risk score incorporating plasma MMP12 level improves prediction of abdominal aortic aneurysm.
Clark MG; Yuan S; Larsson SC; Levin MG; Woerner J; Kim D; Damrauer SM
Article: CELL REPORTS MEDICINE. 2025;6(12):102481
Association of female reproductive traits with altered aging trajectories: Insights from genetic and observational analyses
Lou C; Wang G; Xiong Z; Jiang YC; Li Y; Zhu M; Yang H; Wang L; He L; Chang H-M; Wang J; Zhu W; Dong X; Li TY; Yuan S; Zhao Y; Mu L
Article: ADVANCED SCIENCE. 2025;12(47):e07691
Diagnosis, Prognosis, and Drug Target Discovery for Chronic Widespread Pain: A Large Proteogenomic Study
Chen L; Kelleher E; Meng R; Liu D; Guo Y; Wang Y; Gao Y; Huang Z; Liang Z; Yuan S; Zeng C; Ma J; Dong Y; Irani A; Lei G; Xie J; Prieto-Alhambra D
Journal article: PATHOPHYSIOLOGY. 2025;32(4):66
Calcification in Vascular Smooth Muscle Cells Is Associated with Elevated GCLm and Impaired Contraction: Insights into Osteogenic Transdifferentiation and Therapeutic Approaches
Delgadillo LF; Rashdan NA; Hamilton H; Pattillo JH; Yuan S; Eshaq RS; Harris NR; Alexander JS; Pattillo CB
Article: CLINICAL GASTROENTEROLOGY AND HEPATOLOGY. 2025;:S1542-3565(25)00997-8
Circulating Metabolite Signatures Linking Physical Activity to Inflammatory Bowel Disease Risk and Interactions With Genetic Susceptibility.
He Z; Sun Y; Huang H; Fu T; Yuan S; Larsson SC; Wolk A; Ludvigsson JF; Wang X; Li X; Burisch J; Magro F; Bai Y; Chen J
Article: GENOMICS PROTEOMICS & BIOINFORMATICS. 2025;23(5):qzaf101
Cross-ethnic Molecular Signatures Underpin the Adverse Impact of Statin Use on Type 2 Diabetes
Xu F; Yang M; Hu W; Yuan S; Cai X; Gou W; Miao Z; Li B-Y; Yue L; Xue Z; Shuai M; Shen L; Fu Y; Guo T; Chen Y-M; Zheng J-S
Journal article: SCIENCE CHINA-MATERIALS. 2025;68(10):3703-3714
Low-power plasmonic SiC nanowire network-based artificial photo-synaptic device for musical classification neural network systems
Chen M; Wei G; Yuan S; Li Y; Wang P; Su Y; Ding L; Wang R; Shen G
Journal article: BIORXIV. 2025;:2025.09.17.676962
CYB5R4 sustains endothelial proliferation and ischemia-induced angiogenesis by maintaining RRM2-dependent nucleotide balance.
Yuan S; Hahn SA; Colussi NC; Mullett SJ; Gelhaus SL; Schopfer FJ; Straub AC
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2025;45(9):1683-1692
Circulating Protein Mediators Linking Genetically Predicted Smoking to Abdominal Aortic Aneurysm: A Genomic-Proteomic Analysis
Yuan S; Khodursky S; Geng J; Sharma P; Spin JM; Tsao PS; Levin MG; Damrauer SM
Article: CLINICAL GASTROENTEROLOGY AND HEPATOLOGY. 2025;23(9):1623-1632.e16
Dietary Antioxidant Capacity, Genetic Susceptibility and Polymorphism, and Inflammatory Bowel Disease Risk in a Prospective Cohort
Chen J; Dan L; Yuan S; Fu T; Sun J; Wolk A; Ludvigsson JF; Li X; Wang X; Larsson SC
Article: NATURE COMMUNICATIONS. 2025;16(1):6426
Cross-population GWAS and proteomics improve risk prediction and reveal mechanisms in atrial fibrillation
Yuan S; Chen J; Ruan X; Li Y; Abramowitz SA; Wang L; Jiang F; Xiong Y; Levin MG; Voight BF; Gill D; Burgess S; Akesson A; Michaelsson K; Li X; Damrauer SM; Larsson SC
Journal article: THERANOSTICS. 2025;15(15):7779-7801
Harnessing mRNA for heart health: a new era in cardiovascular treatment
Peng F; Qiu Z; Wang Z; Li F; Zhou F; Yuan S; Yuan J; Wang Y; Zhao Y; Li C; Shi B
Journal article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2025;45(7):e286-e306
Impaired CAMK4 Activity Limits Atherosclerosis and Reprograms Myelopoiesis
Gonzalez AL; Youwakim CM; Leake BF; Fuller KK; Rahman SMJ; Dungan MM; Gu K; Bonin JL; Cavnar AB; Michell DL; Davison LM; Cutchins C; Chu YE; Yuan S; Yurdagul A; Traylor JG; Orr AW; Kohutek ZA; Linton MF; Macnamara KC; Ferrell PB; Vickers KC; Madhur MS; Brown JD; Doran AC
Journal article: CORROSION SCIENCE. 2025;250:112905
Enhancing corrosion resistance of Mg-Nd-Zr-In alloys via the development of a triple-layered In (Indium) rich corrosion product film
Ci W; Tao Q; Chen X; Blawert C; Serdechnova M; Song C; Yuan S; Pan F; Zheludkevich ML
Article: JHEP REPORTS. 2025;7(5):101369
Thyroid dysfunction in MASLD: Results of a nationwide study
Yuan S; Ebrahimi F; Bergman D; Vujkovic M; Scorletti E; Ruan X; Chen J; Hagstrom H; Ludvigsson JF
Journal article: JHEP REPORTS. 2025;7(5):101369
Thyroid dysfunction in MASLD: Results of a nationwide study.
Yuan S; Ebrahimi F; Bergman D; Vujković M; Scorletti E; Ruan X; Chen J; Hagström H; Ludvigsson JF
Article: LANCET REGIONAL HEALTH-EUROPE. 2025;52:101264
Composition of plant-based diets and the incidence and prognosis of inflammatory bowel disease: a multinational retrospective cohort study
Chen J; Sun Y; Dan L; Wellens J; Yuan S; Yang H; Tong TYN; Cross AJ; Papadimitriou N; Meyer A; Dahm CC; Larsson SC; Wolk A; Ludvigsson JF; Tsilidis K; Giovannucci E; Satsangi J; Wang X; Theodoratou E; Chan SSM; Li X
Article: RHEUMATOLOGY. 2025;64(5):3012-3018
Modifiable risk factors and inflammation-related proteins in polymyalgia rheumatica: genome-wide meta-analysis and Mendelian randomization
Zhao SS; Mackie SL; Larsson SC; Burgess S; Yuan S
Article: ADVANCED SCIENCE. 2025;12(14):e2411679
Multiomics and Systematic Analyses Reveal the Roles of Hemoglobin and the HIF-1 Pathway in Polycystic Ovary Syndrome
Wang G; Mao W; Zhang Y; Yang H; Zhu M; Li Y; Chen W; Chen Y; Lou C; Li P; Chang H-M; Yuan S; Zhao Y; Mu L
Article: CIRCULATION-GENOMIC AND PRECISION MEDICINE. 2025;18(2):e004933
Evaluating the Cardiometabolic Efficacy and Safety of Lipoprotein Lipase Pathway Targets in Combination With Approved Lipid-Lowering Targets: A Drug Target Mendelian Randomization Study
Gagnon E; Gill D; Chabot D; Cronje HT; Yuan S; Brennan S; Theriault S; Burgess S; Arsenault BJ; Dib M-J
Article: NATURE COMMUNICATIONS. 2025;16(1):2481
GWAS identifies genetic loci, lifestyle factors and circulating biomarkers that are risk factors for sarcoidosis
Yuan S; Chen J; Geng J; Zhao SS; Yarmolinsky J; Arkema EV; Abramowitz S; Levin MG; Tsilidis KK; Burgess S; Damrauer SM; Larsson SC
Article: JNCI CANCER SPECTRUM. 2025;9(2):pkaf014
Genome-wide association study and Mendelian randomization analyses reveal insights into bladder cancer etiology
Larsson SC; Chen J; Ruan X; Li X; Yuan S
Article: EBIOMEDICINE. 2025;113:105580
Cardio-metabolic-related plasma proteins reveal biological links between cardiovascular diseases and fragility fractures: a cohort and Mendelian randomisation investigation
Michalsson K; Zheng R; Baron JA; Fall T; Wolk A; Lind L; Hoijer J; Brunius C; Lemming EW; Titova OE; Svennblad B; Larsson SC; Yuan S; Melhus H; Byberg L; Brooke HL
Article: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 2025;54(2):dyaf020
Factorial Mendelian randomization of lipoprotein (a) lowering, low-density lipoprotein cholesterol lowering, and lifestyle improvements: joint associations with cardiovascular risk
Wang L; Jiang F; Sun J; Zhao J; He Y; Gill D; Burgess S; Larsson SC; Yuan S; Li X
Article: JOURNAL OF DIABETES. 2025;17(2):e70056
Glucokinase Regulatory Protein as a Putative Target for Gestational Diabetes Mellitus and Related Complications: Evidence From the Mendelian Randomization Study
Mao W; Wang G; Wang X; Shen Y; Yuan S; Wang L; Yang H; Li Y; Chen K; Liu J; Dong X; Zhao Y; Mu L
Article: DIABETES OBESITY & METABOLISM. 2025;27(2):866-875
Network Mendelian randomisation analysis deciphers protein pathways linking type 2 diabetes and gastrointestinal disease
Geng J; Ruan X; Wu X; Chen X; Fu T; Gill D; Burgess S; Chen J; Ludvigsson JF; Larsson SC; Li X; Du Z; Yuan S
Journal article: EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY. 2025;32(2):149-155
Association between alcohol consumption and peripheral artery disease: two de novo prospective cohorts and a systematic review with meta-analysis.
Yuan S; Wu J; Chen J; Sun Y; Burgess S; Li X; Åkesson A; Larsson SC
Article: GASTROENTEROLOGY REPORT. 2025;13:goaf057
Unveiling CTRB2, RSPO3, KLOTB, and ROR1 as obesity-pancreatic disease association proteins: a comprehensive Mendelian randomization study
Zhou C; Ruan X; Che T; Zhang Y; Yuan S; Li X; Zheng J; Cao X; Chen J; Wang X; Zou D
Article: JVS - VASCULAR SCIENCE. 2025;6:100290
Plasma proteome-wide Mendelian randomization reveals the association of extracellular matrix proteins with abdominal aortic aneurysm
Khodursky S; Yuan S; Spin JM; Tsao PS; Levin MG; Damrauer SM
Article: HUMAN REPRODUCTION. 2024;39(12):2785-2797
Mendelian randomization and multi-omics approach analyses reveal impaired glucose metabolism and oxidative phosphorylation in visceral adipose tissue of women with polycystic ovary syndrome
Zhang Y; Jiang X; Song X; Zhang J; Mao W; Chen W; Yuan S; Chen Y; Mu L; Zhao Y
Article: EBIOMEDICINE. 2024;110:105443
Exposure to air pollution increases susceptibility to ulcerative colitis through epigenetic alterations in CXCR2 and MHC class III region
Chen J; Zhang H; Fu T; Zhao J; Nowak JK; Kalla R; Wellens J; Yuan S; Noble A; Ventham NT; Dunlop MG; Halfvarson J; Mao R; Theodoratou E; Satsangi J; Li X
Article: EUROPEAN HEART JOURNAL. 2024;45(43):4647-4657
Plasma proteome and incident myocardial infarction: sex-specific differences
Titova OE; Yuan S; Byberg L; Baron JA; Lind L; Michaelsson K; Larsson SC
Article: MED. 2024;5(11):1413-1423.e3
Multisystem health comorbidity networks of metabolic dysfunction-associated steatotic liver disease
Jiang F; Wang L; Ying H; Sun J; Zhao J; Lu Y; Bian Z; Chen J; Fang A; Zhang X; Larsson SC; Mantzoros CS; Wang W; Yuan S; Ding Y; Li X
Journal article: FRONTIERS IN GENETICS. 2024;15:1425591
Identification of plasma exosomal lncRNA as a biomarker for early diagnosis of gastric cancer
Wei Y; Hu X; Yuan S; Zhao Y; Zhu C; Guo M; Cui H
Journal article: ESC HEART FAILURE. 2024;11(5):2481-2912
Impact of heart rate changes during hospitalization on outcome in heart failure with preserved ejection fraction
Liu D; Cui X; Xu Y; Xu L; Xie Z; Yuan S; Wang P; Wang Y; Qian S; Gong H; Nordbeck P; Yang J; Zhou J; Ge J; Sun A
Journal article: NANOSCALE HORIZONS. 2024;9(10):1813-1822
Harnessing a silicon carbide nanowire photoelectric synaptic device for novel visual adaptation spiking neural networks
Feng Z; Yuan S; Zou J; Wu Z; Li X; Guo W; Tan S; Wang H; Hao Y; Ruan H; Lin Z; Xu Z; Zhu Y; Wei G; Dai Y
Journal article: 2024
Systematic Investigation of Plasma Proteome to Discover Potential Interventional Targets and Prediction Biomarkers for Chronic Liver Diseases
Li X; Sun J; Zhou S; Zhao J; Jiang F; Li T; Zhang M; Li J; Yuan S; Li X; Ding Y
Journal article: SMALL. 2024;20(34):e2400458
SiC@NiO Core-Shell Nanowire Networks-Based Optoelectronic Synapses for Neuromorphic Computing and Visual Systems at High Temperature
Shen W; Wang P; Wei G; Yuan S; Chen M; Su Y; Xu B; Li G
Journal article: ADVANCED SCIENCE. 2024;11(29):e2403665
Highly Promising 2D/1D BP-C/CNT Bionic Opto-Olfactory Co-Sensory Artificial Synapses for Multisensory Integration
Dong L; Xue B; Wei G; Yuan S; Chen M; Liu Y; Su Y; Niu Y; Xu B; Wang P
Journal article: CORROSION SCIENCE. 2024;236:112256
Service performance of novel advanced environmental barrier coatings at ultra-high temperature of 1475 °C in steam environment
Zhang Z; Meng Y; Yuan S; Wang H; Gyawali G; Xue Z; Park Y; Kim DH; Zhang S; Byon E; Park H
Article: JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE. 2024;116(8):1303-1312
Systematic investigation of genetically determined plasma and urinary metabolites to discover potential interventional targets for colorectal cancer
Sun J; Zhao J; Zhou S; Li X; Li T; Wang L; Yuan S; Chen D; Law PJ; Larsson SC; Farrington SM; Houlston RS; Dunlop MG; Theodoratou E; Li X
Article: DIABETOLOGIA. 2024;67(8):1630-1641
Coeliac disease and type 2 diabetes risk: a nationwide matched cohort and Mendelian randomisation study
Yuan S; Leffler D; Lebwohl B; Green PHR; Sun J; Carlsson S; Larsson SC; Ludvigsson JF
Journal article: PLOS ONE. 2024;19(7):e0303472
STING inhibition enables efficient plasmid-based gene expression in primary vascular cells: A simple and cost-effective transfection protocol
Yuan S; Straub AC
Article: FERTILITY AND STERILITY. 2024;122(1):162-173
Association of serum uric acid with women 's ovarian reserve: observational study and Mendelian randomization analyses
Wang G; Yang H; Jiang X; Mao W; Li P; Lin X; Li Y; Ye Z; Zhang Y; Chen W; Yuan S; Zhao Y; Mu L
Article: ISCIENCE. 2024;27(6):109931
Sleep, physical activity, and sedentary behaviors in relation to overall cancer and site-specific cancer risk: A prospective cohort study
Zhang R; Lu Y; Bian Z; Zhou S; Xu L; Jiang F; Yuan S; Tan X; Chen X; Ding Y; Li X
Article: EUROPEAN HEART JOURNAL-QUALITY OF CARE AND CLINICAL OUTCOMES. 2024;10(4):357-365
Risk of incident cardiovascular disease among patients with gastrointestinal disorder: a prospective cohort study of 330751 individuals
Chen J; Sun Y; Fu T; Lu S; Shi W; Zhao J; Li S; Li X; Yuan S; Larsson SC
Article: CLINICAL NUTRITION. 2024;43(6):1386-1394
Ultra-processed foods and human health: An umbrella review and updated meta-analyses of observational evidence
Dai S; Wellens J; Yang N; Li D; Wang J; Wang L; Yuan S; He Y; Song P; Munger R; Kent MP; MacFarlane AJ; Mullie P; Duthie S; Little J; Theodoratou E; Li X
Article: STROKE. 2024;55(6):1582-1591
Risk Factors for Intracerebral Hemorrhage: Genome-Wide Association Study and Mendelian Randomization Analyses
Larsson SC; Chen J; Gill D; Burgess S; Yuan S
Article: INTERNATIONAL JOURNAL OF CANCER. 2024;154(10):1709-1718
Healthy lifestyle and cancer survival: A multinational cohort study
Bian Z; Zhang R; Yuan S; Fan R; Wang L; Larsson SC; Theodoratou E; Zhu Y; Wu S; Ding Y; Li X
Journal article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2024;44:a3117
Cannabis Use Disorder And The Risk Of Atherosclerotic Cardiovascular Diseases
Sharma P; Paranjpe I; Judy R; Yuan S; Lee DJ; Nathanson KL; Levin MG; Damrauer SM
Journal article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2024;44:a1009
Elevated Lipoprotein (a) Is Associated With Increased Risk Of Abdominal Aortic Aneurysm
Sharma P; Judy R; Yuan S; Gellatly C; Saxby K; Bown MJ; Levin MG; Damrauer SM
Article: EBIOMEDICINE. 2024;103:105110
Sedentary lifestyle, physical activity, and gastrointestinal diseases: evidence from mendelian randomization analysis
Chen J; Ruan X; Fu T; Lu S; Gill D; He Z; Burgess S; Giovannucci EL; Larsson SC; Deng M; Yuan S; Li X
Article: EBIOMEDICINE. 2024;103:105126
Impact of ambient air pollution on colorectal cancer risk and survival: insights from a prospective cohort and epigenetic Mendelian randomization study
Jiang F; Zhao J; Sun J; Chen W; Zhao Y; Zhou S; Yuan S; Timofeeva M; Law PJ; Larsson SC; Chen D; Houlston RS; Dunlop MG; Theodoratou E; Li X
Article: EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY. 2024;32(2):149-155
Association between alcohol consumption and peripheral artery disease: two de novo prospective cohorts and a systematic review with meta-analysis
Yuan S; Wu J; Chen J; Sun Y; Burgess S; Li X; Akesson A; Larsson SC
Journal article: JOURNAL OF MATERIALS CHEMISTRY C. 2024;12(15):5529-5537
A passivation strategy assisting a robust and low consumption power BP-based optical synaptic device for neural computing
Zeng J; Ding L; Yuan S; Feng Z; Dong L; Shen W; Wang P; Wu Z; Wei G
Journal article: SMALL. 2024;20(13):e2306998
Artificial Optoelectronic Synapse Based on Violet Phosphorus Microfiber Arrays
Dong L; Yuan S; Wei G; Zhu P; Ma S; Xu B; Yang Y
Article: EBIOMEDICINE. 2024;101:105033
Phenome-wide Mendelian randomization analysis reveals multiple health comorbidities of coeliac disease
Yuan S; Jiang F; Chen J; Lebwohl B; Green PHR; Leffer D; Larsson SC; Li X; Ludvigsson JF
Article: AMERICAN JOURNAL OF PREVENTIVE MEDICINE. 2024;66(3):516-525
Digestive System Diseases, Genetic Risk, and Incident Dementia: A Prospective Cohort Study
Yuan S; Dan L; Zhang Y; Wu J; Zhao J; Kivipelto M; Chen J; Ludvigsson JF; Li X; Larsson SC
Article: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2024;22(3):738-748
Proteomic insights into modifiable risk of venous thromboembolism and cardiovascular comorbidities
Yuan S; Xu F; Zhang H; Chen J; Ruan X; Li Y; Burgess S; Akesson A; Li X; Gill D; Larsson SC
Article: BMC MEDICINE. 2024;22(1):81
Genetic investigation into the broad health implications of caffeine: evidence from phenome-wide, proteome-wide and metabolome-wide Mendelian randomization
Zagkos L; Cronje HT; Woolf B; de La Harpe R; Burgess S; Mantzoros CS; Elliott P; Yuan S; Larsson SC; Tzoulaki I; Gill D
Journal article: SOLAR RRL. 2024;8(4)
Multiscale Simulations Facilitate the Design of High-Performance Perovskite Solar Cells
Yu G; Wang W; Attique S; Yuan S
Journal article: CORROSION SCIENCE. 2024;227:111770
Corrosion behavior of YxYb(2_x)Si2O7 environmental barrier coating materials against molten calcium-magnesium-aluminosilicate (CMAS) at 1475 °C
Zhang Z; Xue Z; Wang H; Yuan S; Park Y; Qiu Z; Qiao L; Gyawali G; Zhang S; Park H; Byon E
Article: JOURNAL OF AUTOIMMUNITY. 2024;143:103170
Older age of celiac disease diagnosis and risk of autoimmune disease: A nationwide matched case-control study
Yuan S; Leffler D; Lebwohl B; Green PHR; Larsson SC; Soderling J; Sun J; Ludvigsson JF
Article: AMERICAN JOURNAL OF HEMATOLOGY. 2024;99(2):172-181
Long-term risk of venous thromboembolism among patients with gastrointestinal non-neoplastic and neoplastic diseases: A prospective cohort study of 484?211 individuals
Yuan S; Sun Y; Chen J; Li X; Larsson SC
Journal article: JOURNAL OF CROHNS & COLITIS. 2024;18:i2069-i2070
Multimorbidity and Disease Trajectories in Patients with INFLAMMATORY BOWEL DISEASES: Insights from Observational and Genetic Analyses
Jiang F; Zhao J; Chen J; Wang L; Yuan S; Kalla R; Wellens J; Nowak J; Larrson S; Ludvigsson J; Satsangi J; Theodoratou E; Li X
Journal article: JVS - VASCULAR SCIENCE. 2024;5:100258
Associations of Genetic and Lifestyle Risk Factors With Incident Peripheral Artery Disease: A Prospective Cohort Study
Yuan S; Sun Y; Chen J; Sharma P; Levin MG; Larsson S; Damrauer SM
Journal article: THERANOSTICS. 2024;14(15):5793-5808
Knocking out USP7 attenuates cardiac fibrosis and endothelial-to-mesenchymal transition by destabilizing SMAD3 in mice with heart failure with preserved ejection fraction
Yuan S; Wang Z; Yao S; Wang Y; Xie Z; Wang J; Yu X; Song Y; Cui X; Zhou J; Ge J
Article: EBIOMEDICINE. 2024;99:104934
Multi-omic insight into the molecular networks of mitochondrial dysfunction in the pathogenesis of inflammatory bowel disease
Chen J; Ruan X; Sun Y; Hu S; Yuan S; Li X
Journal article: EUROPACE. 2023;26(1):euad363
Ablation for atrial fibrillation improves the outcomes in patients with heart failure with preserved ejection fraction
Xie Z; Qi B; Wang Z; Li F; Chen C; Li C; Yuan S; Yao S; Zhou J; Ge J
Article: BMC MEDICINE. 2023;21(1):485
Proteomic insights into the associations between obesity, lifestyle factors, and coronary artery disease
Yang F; Xu F; Zhang H; Gill D; Larsson SC; Li X; Cui H; Yuan S
Article: JOURNAL OF HUMAN GENETICS. 2023;68(12):805-812
Proteome-wide mendelian randomization identifies causal plasma proteins in venous thromboembolism development
Li H; Zhang Z; Qiu Y; Weng H; Yuan S; Zhang Y; Zhang Y; Xi L; Xu F; Ji X; Hao R; Yang P; Chen G; Zuo X; Zhai Z; Wang C
Journal article: JACC: ADVANCES. 2023;2(9):100671
30-Day Outcomes of Transcatheter Tricuspid Annuloplasty With the K-Clip System A Single-Center, Observational Study
Xu H; Li W; Lee AP-W; Wu S; Husanova F; Wu B; Mou Y; Gu Y; Chen M; Tao T; Zhang Y; Zheng J; Yang A; Yuan S; Wang Q; Ni Y; Ma L
Article: INTERNATIONAL JOURNAL OF CANCER. 2023;153(9):1602-1611
Association between antibiotic use during early life and early-onset colorectal cancer risk overall and according to polygenic risk and FUT2 genotypes
Jiang F; Boakye D; Sun J; Wang L; Yu L; Zhou X; Zhao J; Bian Z; Song P; He Y; Zhu Y; Chen J; Yuan S; Song M; Larsson SC; Giovannucci EL; Theodoratou E; Ding K; Li X
Article: CYTOTHERAPY. 2023;25(11):1155-1166
Single-cell transcriptome analysis reveals the effectiveness of cytokine priming irrespective of heterogeneity in mesenchymal stromal cells
Wan Z; Chen Y-F; Pan Q; Wang Y; Yuan S; Chin HY; Wu H-H; Lin W-T; Cheng P-Y; Yang Y-J; Wang Y-F; Kumta SM; Lee C-W; Lee OK-S
Article: FRONTIERS IN ENDOCRINOLOGY. 2023;14:1278273
Apolipoprotein B and interleukin 1 receptor antagonist: reversing the risk of coronary heart disease
Yang F; Huangfu N; Shen J; Su P; Zhu L; Cui H; Yuan S
Article: INTERNATIONAL JOURNAL OF CANCER. 2023;153(8):1477-1486
Exploring the cross-cancer effect of smoking and its fingerprints in blood DNA methylation on multiple cancers: A Mendelian randomization study
Zhou Y; Zhou X; Sun J; Wang L; Zhao J; Chen J; Yuan S; He Y; Timofeeva M; Spiliopoulou A; Mesa-Eguiagaray I; Farrington SM; Ding K; Dunlop MG; Qian X; Theodoratou E; Li X
Article: BRITISH JOURNAL OF CANCER. 2023;129(8):1306-1313
Dissecting the pathogenic effects of smoking and its hallmarks in blood DNA methylation on colorectal cancer risk
Zhou X; Xiao Q; Jiang F; Sun J; Wang L; Yu L; Zhou Y; Zhao J; Zhang H; Yuan S; Timofeeva M; Spiliopoulou A; Mesa-Eguiagaray I; Farrington SM; Law PJ; Houlston RS; Ding K; Dunlop MG; Theodoratou E; Li X
Article: OBESITY. 2023;31(10):2603-2614
Birth weight, childhood obesity, adulthood obesity and body composition, and gastrointestinal diseases: a Mendelian randomization study
Yuan S; Ruan X; Sun Y; Fu T; Zhao J; Deng M; Chen J; Li X; Larsson SC
Article: FOOD & FUNCTION. 2023;14(18):8597-8603
A nutrient-wide association study for the risk of cardiovascular disease in the China Health and Nutrition Survey (CHNS) and the National Health and Nutrition Examination Survey (NHANES)
Zhang M-J; Zhang M-Z; Yuan S; Yang H-G; Lu G-L; Chen R; He Q-Q
Article: GENOME MEDICINE. 2023;15(1):75
Identification of novel protein biomarkers and drug targets for colorectal cancer by integrating human plasma proteome with genome
Sun J; Zhao J; Jiang F; Wang L; Xiao Q; Han F; Chen J; Yuan S; Wei J; Larsson SC; Zhang H; Dunlop MG; Farrington SM; Ding K; Theodoratou E; Li X
Article: CELL REPORTS MEDICINE. 2023;4(9):101174
Plasma proteins and onset of type 2 diabetes and diabetic complications: Proteome-wide Mendelian randomization and colocalization analyses
Yuan S; Xu F; Li X; Chen J; Zheng J; Mantzoros CS; Larsson SC
Article: FRONTIERS IN IMMUNOLOGY. 2023;14:1240754
Therapeutic role of interleukin-1 receptor antagonist in pancreatic diseases: mendelian randomization study
Yuan S; Miao Y; Ruan X; Chen J; Li X; Larsson SC
Journal article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2023;43(9):1626-1635
Spatially Resolved Metabolites in Stable and Unstable Human Atherosclerotic Plaques Identified by Mass Spectrometry Imaging
Seeley EH; Liu Z; Yuan S; Stroope C; Cockerham E; Rashdan NA; Delgadillo LF; Finney AC; Kumar D; Das S; Razani B; Liu W; Traylor J; Orr AW; Rom O; Pattillo CB; Yurdagul Jr A
Article: CLINICAL NUTRITION. 2023;42(8):1268-1275
Ultra-processed food intake and incident venous thromboembolism risk: Prospective cohort study
Yuan S; Chen J; Fu T; Li X; Bruzelius M; Akesson A; Larsson SC
Journal article: SCIENCE CHINA-MATERIALS. 2023;66(8):3238-3250
Silicon carbide nanowire-based multifunctional and efficient visual synaptic devices for wireless transmission and neural network computing
Yuan S; Feng Z; Qiu B; Li Y; Zhai P; Li L; Wu Z; Ma S; Xu B; Ding L; Wei G; Shen G
Article: JOURNAL OF NUTRITION. 2023;153(8):2291-2297
Higher Adherence to Cardioprotective Diet is Associated with Reduced Risk of Enterotomy and All-Cause Mortality among 5549 Individuals with Inflammatory Bowel Disease in a Prospective Cohort Study
Dan L; Yuan S; Ruan X; Sun Y; Fu T; Chen J; Li X
Article: EUROPEAN JOURNAL OF CLINICAL NUTRITION. 2023;77(8):811-814
Genetically predicted coffee and tea consumption and risk of intracranial aneurysm
Zhang Z; Wang M; Yuan S; Larsson SCC; Liu X
Article: CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION. 2023;32(8):1048-1060
Field Synopsis of Environmental and Genetic Risk Factors of Sporadic Early-Onset Colorectal Cancer and Advanced Adenoma
Zhang R; Boakye D; Yang N; Zhou X; Zhou Y; Jiang F; Yu L; Wang L; Sun J; Yuan S; Chen J; Hamilton AC; Coleman HG; Larsson SC; Little J; Dunlop MG; Giovannucci EL; Theodoratou E; Li X
Article: BMJ ONCOLOGY. 2023;2(1):e000049
Global trends in incidence, death, burden and risk factors of early-onset cancer from 1990 to 2019
Zhao J; Xu L; Sun J; Song M; Wang L; Yuan S; Zhu Y; Wan Z; Larsson S; Tsilidis K; Dunlop M; Campbell H; Rudan I; Song P; Theodoratou E; Ding K; Li X
Article: JOURNAL OF THE ENDOCRINE SOCIETY. 2023;7(8):bvad090
Physical Activity, Sedentary Behavior, and Type 2 Diabetes: Mendelian Randomization Analysis
Yuan S; Li X; Liu Q; Wang Z; Jiang X; Burgess S; Larsson SC
Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2023;131(7):77010
Ambient Air Pollution and Risk of Enterotomy, Gastrointestinal Cancer, and All-Cause Mortality among 4,708 Individuals with Inflammatory Bowel Disease: A Prospective Cohort Study
Chen J; Dan L; Sun Y; Yuan S; Liu W; Chen X; Jiang F; Fu T; Zhang H; Deng M; Wang X; Li X
Article: FRONTIERS IN MEDICINE. 2023;10:1180596
Atopic dermatitis and chronic kidney disease: a bidirectional Mendelian randomization study
Zhang H; Yuan S; Li Y; Li D; Yu Z; Hu L; Li X; Wang Y; Larsson SC
Article: HUMAN MOLECULAR GENETICS. 2023;32(12):2093-2102
Cross-cancer pleiotropic analysis identifies three novel genetic risk loci for colorectal cancer
Sun J; Wang L; Zhou X; Hu L; Yuan S; Bian Z; Chen J; Zhu Y; Farrington SM; Campbell H; Ding K; Zhang D; Dunlop MG; Theodoratou E; Li X
Article: CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION. 2023;32(6):809-817
Exploring the Complex Relationship between Gut Microbiota and Risk of Colorectal Neoplasia Using Bidirectional Mendelian Randomization Analysis
Li W; Zhou X; Yuan S; Wang L; Yu L; Sun J; Chen J; Xiao Q; Wan Z; Zheng J-S; Zhang C-X; Larsson SC; Farrington SM; Law P; Houlston RS; Tomlinson I; Ding K-F; Dunlop MG; Theodoratou E; Li X
Article: MOLECULAR NEUROBIOLOGY. 2023;60(6):3004-3009
Serum Calcium, 25-Hydroxyvitamin D, and Parathyroid Hormone Levels in Relation to Aneurysmal Subarachnoid Hemorrhage
Zhang Z; Yuan S; Larsson SC; Wang M; Liu X
Article: TRANSLATIONAL PSYCHIATRY. 2023;13(1):146
Depression and 24 gastrointestinal diseases: a Mendelian randomization study
Ruan X; Chen J; Sun Y; Zhang Y; Zhao J; Wang X; Li X; Yuan S; Larsson SCC
Article: JOURNAL OF CROHNS & COLITIS. 2023;17(5):777-785
Bidirectional Mendelian Randomisation Analysis Provides Evidence for the Causal Involvement of Dysregulation of CXCL9, CCL11 and CASP8 in the Pathogenesis of Ulcerative Colitis
Chen J; Zhou Y; Sun Y; Yuan S; Kalla R; Sun J; Zhao J; Wang L; Chen X; Zhou X; Dai S; Zhang Y; Ho G-T; Xia D; Cao Q; Liu Z; Larsson SC; Wang X; Ding K; Halfvarson J; Li X; Theodoratou E; Satsangi J
Article: EUROPEAN HEART JOURNAL OPEN. 2023;3(3):oead056
Circulating proteins and peripheral artery disease risk: observational and Mendelian randomization analyses
Yuan S; Titova OE; Zhang K; Chen J; Li X; Klarin D; Akesson A; Damrauer SM; Larsson SC
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2023;201(4):783-792
Plasma protein and venous thromboembolism: prospective cohort and mendelian randomisation analyses
Yuan S; Titova OE; Zhang K; Gou W; Schillemans T; Natarajan P; Chen J; Li X; Akesson A; Bruzelius M; Klarin D; Damrauer SM; Larsson SC
Article: JOURNAL OF CROHNS & COLITIS. 2023;17(4):535-552
Intake of Ultra-processed Foods Is Associated with an Increased Risk of Crohn's Disease: A Cross-sectional and Prospective Analysis of 187 154 Participants in the UK Biobank
Chen J; Wellens J; Kalla R; Fu T; Deng M; Zhang H; Yuan S; Wang X; Theodoratou E; Li X; Satsangi J
Article: DIABETES CARE. 2023;46(4):828-835
Gastrointestinal Consequences of Type 2 Diabetes Mellitus and Impaired Glycemic Homeostasis: A Mendelian Randomization Study
Chen J; Yuan S; Fu T; Ruan X; Qiao J; Wang X; Li X; Gill D; Burgess S; Giovannucci EL; Larsson SC
Journal article: FRONTIERS IN ONCOLOGY. 2023;13:1043869
Prediction of cardiovascular adverse events in newly diagnosed multiple myeloma: Development and validation of a risk score prognostic model
Yuan S; Zhou J-Y; Yang B-Z; Xie Z-L; Zhu T-J; Hu H-X; Li R
Article: EUROPEAN HEART JOURNAL OPEN. 2023;3(2):oead008
Sleep duration, daytime napping, and risk of peripheral artery disease: multinational cohort and Mendelian randomization studies
Yuan S; Levin MG; Titova OE; Chen J; Sun Y; Akesson A; Li X; Damrauer SM; Larsson SC
Article: ALIMENTARY PHARMACOLOGY & THERAPEUTICS. 2023;57(5):475-485
Sleep duration and daytime napping in relation to incident inflammatory bowel disease: a prospective cohort study
Yuan S; Sun Y; Tan X; Geng J; Sun J; Chen X; Yu L; Wang J; Zhou X; Hesketh T; Larsson SC; Chen J; Wang X; Li X; Liu Z
Article: EBIOMEDICINE. 2023;89:104494
Therapeutic targets for inflammatory bowel disease: proteome-wide Mendelian randomization and colocalization analyses
Chen J; Xu F; Ruan X; Sun J; Zhang Y; Zhang H; Zhao J; Zheng J; Larsson SC; Wang X; Li X; Yuan S
Article: EBIOMEDICINE. 2023;89:104488
Mendelian randomization and clinical trial evidence supports TYK2 inhibition as a therapeutic target for autoimmune diseases
Yuan S; Wang L; Zhang H; Xu F; Zhou X; Yu L; Sun J; Chen J; Ying H; Xu X; Yu Y; Spiliopoulou A; Shen X; Wilson J; Gill D; Theodoratou E; Larsson SC; Li X
Article: AMERICAN JOURNAL OF GASTROENTEROLOGY. 2023;118(3):511-522
The Contribution of Genetic Risk and Lifestyle Factors in the Development of Adult-Onset Inflammatory Bowel Disease: A Prospective Cohort Study
Sun Y; Yuan S; Chen X; Sun J; Kalla R; Yu L; Wang L; Zhou X; Kong X; Hesketh T; Ho G-T; Ding K; Dunlop M; Larsson SC; Satsangi J; Chen J; Wang X; Li X; Theodoratou E; Giovannucci EL
Article: INTERNATIONAL JOURNAL OF CANCER. 2023;152(4):697-704
Morning chronotype and digestive tract cancers: Mendelian randomization study
Yuan S; Mason AM; Titova OE; Vithayathil M; Kar S; Chen J; Li X; Burgess S; Larsson SC
Article: ELIFE. 2023;12:e84051
Smoking, alcohol consumption, and 24 gastrointestinal diseases: Mendelian randomization analysis
Yuan S; Chen J; Ruan X; Sun Y; Zhang K; Wang X; Li X; Gill D; Burgess S; Giovannucci E; Larsson SC
Article: CLINICAL GASTROENTEROLOGY AND HEPATOLOGY. 2023;21(2):398-405.e4
Inverse Association Between Serum 25-Hydroxyvitamin D and Nonalcoholic Fatty Liver Disease
Yuan S; Larsson SC
Article: NUTRITION. 2023;106:111910
Plasma phospholipid arachidonic acid in relation to non-alcoholic fatty liver disease: Mendelian randomization study
Chen J; Ruan X; Sun Y; Li X; Yuan S; Larsson SC
Article: ALIMENTARY PHARMACOLOGY & THERAPEUTICS. 2023;57(4):399-408
Antioxidants, minerals and vitamins in relation to Crohn's disease and ulcerative colitis: A Mendelian randomization study
Chen J; Ruan X; Yuan S; Deng M; Zhang H; Sun J; Yu L; Satsangi J; Larsson SC; Therdoratou E; Wang X; Li X
Journal article: FOOD & FUNCTION. 2023;14(18):8597-8603
A nutrient-wide association study for the risk of cardiovascular disease in the China Health and Nutrition Survey (CHNS) and the National Health and Nutrition Examination Survey (NHANES)
Zhang M-J; Zhang M-Z; Yuan S; Yang H-G; Lu G-L; Chen R; He Q-Q
Journal article: FRONTIERS IN IMMUNOLOGY. 2023;14:1240754
Therapeutic role of interleukin-1 receptor antagonist in pancreatic diseases: mendelian randomization study.
Yuan S; Miao Y; Ruan X; Chen J; Li X; Larsson SC
Article: AMERICAN JOURNAL OF CLINICAL NUTRITION. 2022;116(6):1595-1609
Homocysteine, folate, and nonalcoholic fatty liver disease: a systematic review with meta-analysis and Mendelian randomization investigation
Yuan S; Chen J; Dan L; Xie Y; Sun Y; Li X; Larsson SC
Article: ARTHRITIS RESEARCH & THERAPY. 2022;24(1):270
Rheumatoid arthritis and risk of site-specific cancers: Mendelian randomization study in European and East Asian populations
Yuan S; Chen J; Ruan X; Vithayathil M; Kar S; Li X; Mason AM; Burgess S; Larsson SC
Article: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 2022;51(6):1931-1942
Genetically predicted sex hormone levels and health outcomes: phenome-wide Mendelian randomization investigation
Yuan S; Wang L; Sun J; Yu L; Zhou X; Yang J; Zhu Y; Gill D; Burgess S; Denny JC; Larsson SC; Theodoratou E; Li X
Journal article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2022;298(12):102654
Cytochrome b5 reductases: Redox regulators of cell homeostasis
Hall R; Yuan S; Wood K; Katona M; Straub AC
Article: JOURNAL OF SLEEP RESEARCH. 2022;31(6):e13681
Self-reported symptoms of sleep-disordered breathing and risk of cardiovascular diseases: Observational and Mendelian randomization findings
Titova OE; Yuan S; Baron JA; Lindberg E; Michaelsson K; Larsson SC
Article: BMC MEDICINE. 2022;20(1):455
Health effects of milk consumption: phenome-wide Mendelian randomization study
Yuan S; Sun J; Lu Y; Xu F; Li D; Jiang F; Wan Z; Li X; Qin L-Q; Larsson SC
Journal article: CIRCULATION. 2022;146(Suppl_1):a11460
Abstract 11460: Sleep Duration, Quality, and Risk of Peripheral Artery Disease: Multinational Cohort and Mendelian Randomization Studies
Yuan S; Levin MG; Titova O; Chen J; Sun Y; Akesson A; Li X; Damrauer SM; Larsson S
Article: GENES. 2022;13(11):2010
Bidirectional Association between Major Depressive Disorder and Gastroesophageal Reflux Disease: Mendelian Randomization Study
Miao Y; Yuan S; Li Y; Chen J; Li X; Larsson SC; Zhang Q
Article: SCIENTIFIC REPORTS. 2022;12(1):17703
A Mendelian randomization study of genetic predisposition to autoimmune diseases and COVID-19
Li S; Yuan S; Schooling CM; Larsson SC
Article: ELIFE. 2022;11:e79720
Genetically predicted high IGF-1 levels showed protective effects on COVID-19 susceptibility and hospitalization: a Mendelian randomisation study with data from 60 studies across 25 countries
Li X; Zhou Y; Yuan S; Zhou X; Wang L; Sun J; Yu L; Zhu J; Zhang H; Yang N; Dai S; Song P; Larsson SC; Theodoratou E; Zhu Y; Li X
Article: DIABETES. 2022;71(10):2222-2232
Differentiating Associations of Glycemic Traits With Atherosclerotic and Thrombotic Outcomes: Mendelian Randomization Investigation
Yuan S; Mason AM; Burgess S; Larsson SC
Article: CLINICAL NUTRITION. 2022;41(10):2113-2123
Coffee consumption and cancer risk: a Mendelian randomisation study
Carter P; Yuan S; Kar S; Vithayathil M; Mason AM; Burgess S; Larsson SC
Article: ARTHRITIS & RHEUMATOLOGY. 2022;74(10):1638-1647
Genetic Liability to Rheumatoid Arthritis in Relation to Coronary Artery Disease and Stroke Risk
Yuan S; Carter P; Mason AM; Yang F; Burgess S; Larsson SC
Journal article: JOURNAL OF CLINICAL INVESTIGATION. 2022;132(18):e147120
Loss of cardiomyocyte CYB5R3 impairs redox equilibrium and causes sudden cardiac death
Carew NT; Schmidt HM; Yuan S; Galley JC; Hall R; Altmann HM; Hahn SA; Miller MP; Wood KC; Gabris B; Stapleton MC; Hartwick S; Fazzari M; Wu YL; Trebak M; Kaufman BA; McTiernan CF; Schopfer FJ; Navas P; Thibodeau PH; McNamara DM; Salama G; Straub AC
Article: NUTRIENTS. 2022;14(16):3354
Plasma Phospholipid Fatty Acids and Risk of Venous Thromboembolism: Mendelian Randomization Investigation
Yuan S; Li X; Morange P-E; Bruzelius M; Larsson SC
Article: SCIENTIFIC REPORTS. 2022;12(1):12139
Swedish snuff (snus) dipping, cigarette smoking, and risk of peripheral artery disease: a prospective cohort study
Yuan S; Titova OE; Damrauer SM; Akesson A; Larsson SC
Article: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2022;64(1):83-91
A Prospective Evaluation of Modifiable Lifestyle Factors in Relation to Peripheral Artery Disease Risk
Yuan S; Damrauer SM; Hakansson N; Akesson A; Larsson SC
Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY. 2022;37(7):747-754
Adiposity, diabetes, lifestyle factors and risk of gastroesophageal reflux disease: a Mendelian randomization study
Yuan S; Larsson SC
Journal article: SCIENCE ADVANCES. 2022;8(26):eabm9138
Immunomodulatory actions of a kynurenine-derived endogenous electrophile.
Carreño M; Pires MF; Woodcock SR; Brzoska T; Ghosh S; Salvatore SR; Chang F; Khoo NKH; Dunn M; Connors N; Yuan S; Straub AC; Wendell SG; Kato GJ; Freeman BA; Ofori-Acquah SF; Sundd P; Schopfer FJ; Vitturi DA
Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY. 2022;37(7):723-733
Lifestyle and metabolic factors for nonalcoholic fatty liver disease: Mendelian randomization study
Yuan S; Chen J; Li X; Fan R; Arsenault B; Gill D; Giovannucci EL; Zheng J-S; Larsson SC
Article: INTERNATIONAL JOURNAL OF CANCER. 2022;151(1):83-94
Alcohol consumption, DNA methylation and colorectal cancer risk: Results from pooled cohort studies and Mendelian randomization analysis
Zhou X; Wang L; Xiao J; Sun J; Yu L; Zhang H; Meng X; Yuan S; Timofeeva M; Law PJ; Houlston RS; Ding K; Dunlop MG; Theodoratou E; Li X
Article: FRONTIERS IN GENETICS. 2022;13:814457
GDF-15 as a Therapeutic Target of Diabetic Complications Increases the Risk of Gallstone Disease: Mendelian Randomization and Polygenic Risk Score Analysis
Yu L; Zhou Y; Wang L; Zhou X; Sun J; Xiao J; Xu X; Larsson SC; Yuan S; Li X
Article: CLINICAL NUTRITION. 2022;41(6):1191-1196
Anti-inflammatory diet and incident peripheral artery disease: Two prospective cohort studies
Yuan S; Bruzelius M; Damrauer SM; Hakansson N; Wolk A; Akesson A; Larsson SC
Journal article: ACS APPLIED MATERIALS & INTERFACES. 2022;14(18):21242-21252
Robust and Low-Power-Consumption Black Phosphorus-Graphene Artificial Synaptic Devices
Yuan S; Qiu B; Amina K; Li L; Zhai P; Su Y; Xue T; Jiang T; Ding L; Wei G
Article: CLINICAL GASTROENTEROLOGY AND HEPATOLOGY. 2022;20(5):1077-1084
Genetically Predicted Adiposity, Diabetes, and Lifestyle Factors in Relation to Diverticular Disease
Yuan S; Larsson SC
Article: JOURNAL OF NEUROLOGY. 2022;269(5):2460-2468
Sleep-disordered breathing-related symptoms and risk of stroke: cohort study and Mendelian randomization analysis
Titova OE; Yuan S; Baron JA; Lindberg E; Michaelsson K; Larsson SC
Article: BMC MEDICINE. 2022;20(1):106
The impact and causal directions for the associations between diagnosis of ADHD, socioeconomic status, and intelligence by use of a bi-directional two-sample Mendelian randomization design
Michaelsson M; Yuan S; Melhus H; Baron JA; Byberg L; Larsson SC; Michaelsson K
Article: SEMINARS IN ARTHRITIS AND RHEUMATISM. 2022;53:151958
Interleukins and rheumatoid arthritis: bi-directional Mendelian randomization investigation
Yuan S; Li X; Lin A; Larsson SC
Article: INTERNATIONAL JOURNAL OF CANCER. 2022;150(7):1134-1140
Selenium and cancer risk: Wide-angled Mendelian randomization analysis
Yuan S; Mason AM; Carter P; Vithayathil M; Kar S; Burgess S; Larsson SC
Journal article: BLOOD. 2022;139(11):1760-1765
SOD2 V16A amplifies vascular dysfunction in sickle cell patients by curtailing mitochondria complex IV activity
Dosunmu-Ogunbi A; Yuan S; Reynolds M; Giordano L; Sanker S; Sullivan M; Stolz DB; Kaufman BA; Wood KC; Zhang Y; Shiva S; Nouraie SM; Straub AC
Journal article: PSYCHOLOGY HEALTH & MEDICINE. 2022;27(3):528-536
Associations of health-risk behaviors with mental health among Chinese children
Zhang J; Liu M-W; Yu H-J; Chen Q-T; Tang B-W; Yuan S; He Q-Q
Article: NUTRIENTS. 2022;14(6):1153
Alcohol, Coffee, and Milk Intake in Relation to Epilepsy Risk
Zhang Z; Wang M; Yuan S; Liu X
Article: CLINICAL GASTROENTEROLOGY AND HEPATOLOGY. 2022;20(3):e529-e537
Obesity, Type 2 Diabetes, Lifestyle Factors, and Risk of Gallstone Disease: A Mendelian Randomization Investigation
Yuan S; Gill D; Giovannucci EL; Larsson SC
Article: EBIOMEDICINE. 2022;76:103865
Health effects of high serum calcium levels: Updated phenome-wide Mendelian randomisation investigation and review of Mendelian randomisation studies
Yuan S; Yu L; Gou W; Wang L; Sun J; Li D; Lu Y; Cai X; Yu H; Yuan C; Zheng J-S; Larsson SC; Theodoratou E; Li X
Article: PAIN. 2022;163(2):e342-e348
Alcohol, coffee consumption, and smoking in relation to migraine: a bidirectional Mendelian randomization study
Yuan S; Daghlas I; Larsson SC
Article: EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY. 2022;28(16):1829-1837
Genetically predicted circulating vitamin C in relation to cardiovascular disease
Yuan S; Zheng J-S; Mason AM; Burgess S; Larsson SC
Article: SCIENTIFIC REPORTS. 2022;12(1):409
Metabolic and lifestyle factors in relation to senile cataract: a Mendelian randomization study
Yuan S; Wolk A; Larsson SC
Article: BMJ MEDICINE. 2022;1(1):e000277
Effects of metabolic traits, lifestyle factors, and pharmacological interventions on liver fat: mendelian randomisation study
Yuan S; Chen J; Vujkovic M; Chang K-M; Li X; Larsson SC; Gill D
Article: JOURNAL OF THROMBOSIS AND THROMBOLYSIS. 2022;53(1):43-50
Causal effect of renal function on venous thromboembolism: a two-sample Mendelian randomization investigation
Yuan S; Bruzelius M; Larsson SC
Article: AMERICAN JOURNAL OF KIDNEY DISEASES. 2022;79(1):9-14.e1
Coffee and Caffeine Consumption and Risk of Kidney Stones: A Mendelian Randomization Study
Yuan S; Larsson SC
Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2021;10(21):e022286
Cardiometabolic, Lifestyle, and Nutritional Factors in Relation to Varicose Veins: A Mendelian Randomization Study
Yuan S; Bruzelius M; Damrauer SM; Larsson SC
Journal article: REDOX BIOLOGY. 2021;47:102166
Cooperation between CYB5R3 and NOX4 via coenzyme Q mitigates endothelial inflammation
Yuan S; Hahn SA; Miller MP; Sanker S; Calderon MJ; Sullivan M; Dosunmu-Ogunbi AM; Fazzari M; Li Y; Reynolds M; Wood KC; St Croix CM; Stolz D; Cifuentes-Pagano E; Navas P; Shiva S; Schopfer FJ; Pagano PJ; Straub AC
Article: NUTRITION. 2021;91-92:111310
Association of food expenditure with life expectancy in the United States, 2001-2014
Li Q-X; Yuan S; Yu Z; Larsson SC; He Q-Q
Article: CLINICAL ENDOCRINOLOGY. 2021;95(5):800-805
Genetically predicted insulin-like growth factor-I in relation to muscle mass and strength
Yuan S; Larsson SC
Article: NPJ GENOMIC MEDICINE. 2021;6(1):86
Serum calcium and 25-hydroxyvitamin D in relation to longevity, cardiovascular disease and cancer: a Mendelian randomization study
Yuan S; Baron JA; Michaelsson K; Larsson SC
Article: JOURNAL OF ALZHEIMERS DISEASE. 2021;83(4):1815-1823
Genetically Predicted Coffee Consumption and Risk of Alzheimer's Disease and Stroke
Zhang Z; Wang M; Yuan S; Cai H; Zhu S-G; Liu X
Article: FERTILITY AND STERILITY. 2021;116(4):1061-1067
Smoking, alcohol and coffee consumption and pregnancy loss: a Mendelian randomization investigation
Yuan S; Liu J; Larsson SC
Article: NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES. 2021;31(10):2831-2838
Anti-inflammatory diet and venous thromboembolism: Two prospective cohort studies
Yuan S; Bruzelius M; Damrauer SM; Hakansson N; Wolk A; Akesson A; Larsson SC
Journal article: HYPERTENSION. 2021;78(4):912-926
Redox Switches Controlling Nitric Oxide Signaling in the Resistance Vasculature and Implications for Blood Pressure Regulation: Mid-Career Award for Research Excellence 2020
Aramide Modupe Dosunmu-Ogunbi A; Galley JC; Yuan S; Schmidt HM; Wood KC; Straub AC
Article: MOLECULAR GENETICS AND METABOLISM. 2021;134(1-2):212-215
Assessing causal associations of obesity and diabetes with kidney stones using Mendelian randomization analysis
Yuan S; Larsson SC
Article: NUTRIENTS. 2021;13(8):2893
Genetically Predicted Milk Intake and Risk of Neurodegenerative Diseases
Zhang Z; Wang M; Yuan S; Larsson SC; Liu X
Article: NUTRIENTS. 2021;13(7):2218
Coffee Consumption and Cardiovascular Diseases: A Mendelian Randomization Study
Yuan S; Carter P; Mason AM; Burgess S; Larsson SC
Article: BRITISH JOURNAL OF CANCER. 2021;124(12):1997-2003
Genetically predicted circulating B vitamins in relation to digestive system cancers
Yuan S; Carter P; Vithayathil M; Kar S; Mason AM; Burgess S; Larsson SC
Article: THROMBOSIS RESEARCH. 2021;202:119-124
Lifestyle factors and venous thromboembolism in two cohort studies
Yuan S; Bruzelius M; Hakansson N; Akesson A; Larsson SC
Article: CLINICAL NUTRITION. 2021;40(6):4180-4186
Egg, cholesterol and protein intake and incident type 2 diabetes mellitus: Results of repeated measurements from a prospective cohort study
Shuai Y; Liu M-W; He Q-Q; Larsson SC
Journal article: FREE RADICAL BIOLOGY AND MEDICINE. 2021;167:321-334
CoenzymeQ in cellular redox regulation and clinical heart failure
Yuan S; Schmidt HM; Wood KC; Straub AC
Article: BRAIN AND BEHAVIOR. 2021;11(5):e02098
Modifiable risk factors for epilepsy: A two-sample Mendelian randomization study
Yuan S; Tomson T; Larsson SC
Article: BMJ OPEN. 2021;11(4):e042762
Urban-rural disparity in cancer incidence in China, 2008-2012: a cross-sectional analysis of data from 36 cancer registers
Yuan S; Xie S-H
Article: BMC MEDICINE. 2021;19(1):97
Homocysteine, B vitamins, and cardiovascular disease: a Mendelian randomization study
Yuan S; Mason AM; Carter P; Burgess S; Larsson SC
Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2021;10(8):e019644
Genetically Proxied Inhibition of Coagulation Factors and Risk of Cardiovascular Disease: A Mendelian Randomization Study
Yuan S; Burgess S; Laffan M; Mason AM; Dichgans M; Gill D; Larsson SC
Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY. 2021;36(4):393-400
Genetic liability to insomnia in relation to cardiovascular diseases: a Mendelian randomisation study
Yuan S; Mason AM; Burgess S; Larsson SC
Article: NPJ GENOMIC MEDICINE. 2021;6(1):27
Gallstone disease, diabetes, calcium, triglycerides, smoking and alcohol consumption and pancreatitis risk: Mendelian randomization study
Yuan S; Giovannucci EL; Larsson SC
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2021;106(4):e1552-e1558
Insulin-like Growth Factor-1, Bone Mineral Density, and Fracture: A Mendelian Randomization Study
Yuan S; Wan Z-H; Cheng S-L; Michaelsson K; Larsson SC
Journal article: MEDICINE. 2021;100(10):e24600
Associations of sleep duration and fruit and vegetable intake with the risk of metabolic syndrome in Chinese adults
Wang M-H; Shi T; Li Q; Chen H-M; Liu M-W; Lu Y-A; He Q; Chen R
Article: SCIENTIFIC REPORTS. 2021;11(1):4296
Genetically predicted education attainment in relation to somatic and mental health
Yuan S; Xiong Y; Michaelsson M; Michaelsson K; Larsson SC
Journal article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2021;41(2):769-782
Xanthine Oxidase Drives Hemolysis and Vascular Malfunction in Sickle Cell Disease
Schmidt HM; Wood KC; Lewis SE; Hahn SA; Williams XM; McMahon B; Baust JJ; Yuan S; Bachman TN; Wang Y; Oh J-Y; Ghosh S; Ofori-Acquah SF; Lebensburger JD; Patel RP; Du J; Vitturi DA; Kelley EE; Straub AC
Article: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2021;19(2):460-469
Overall and abdominal obesity in relation to venous thromboembolism
Yuan S; Bruzelius M; Xiong Y; Hakansson N; Akesson A; Larsson SC
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2021;51(1):78-86
Null association between serum 25-hydroxyvitamin D levels with allergic rhinitis, allergic sensitization and non-allergic rhinitis: A Mendelian randomization study
Feng Q; Bonnelykke K; Ek WE; Chawes BL; Yuan S; Cheung CL; Li GHY; Leung RYH; Cheung BMY
Article: JOURNAL OF NEUROLOGY. 2021;268(1):114-124
An atlas on risk factors for multiple sclerosis: a Mendelian randomization study
Yuan S; Xiong Y; Larsson SC
Article: ANNALS OF NEUROLOGY. 2020;88(6):1229-1236
Circulating Lipoprotein Lipids, Apolipoproteins and Ischemic Stroke
Yuan S; Tang B; Zheng J; Larsson SC
Article: DIABETOLOGIA. 2020;63(11):2359-2371
An atlas on risk factors for type 2 diabetes: a wide-angled Mendelian randomisation study
Yuan S; Larsson SC
Article: SCIENTIFIC REPORTS. 2020;10(1):17475
Causal associations between urinary sodium with body mass, shape and composition: a Mendelian randomization study
Feng Q; Yuan S; Yang Q; Lu Y; Loos RJF; Li GHY; Fei Y; Tsoi MF; Cheung CL; Cheung BMY
Article: EUROPEAN JOURNAL OF NEUROLOGY. 2020;27(10):1913-1917
Interleukin-1 receptor antagonist, interleukin-2 receptor alpha subunit and amyotrophic lateral sclerosis
Yuan S; Roos PM; Larsson SC
Article: INTERNATIONAL JOURNAL OF CANCER. 2020;147(7):1895-1903
Causal associations of thyroid function and dysfunction with overall, breast and thyroid cancer: A two-sample Mendelian randomization study
Yuan S; Kar S; Vithayathil M; Carter P; Mason AM; Burgess S; Larsson SC
Article: CLINICAL NUTRITION. 2020;39(10):3119-3124
Causal associations of iron status with gout and rheumatoid arthritis, but not with inflammatory bowel disease
Yuan S; Larsson S
Article: EBIOMEDICINE. 2020;59:102956
Effects of tumour necrosis factor on cardiovascular disease and cancer: A two-sample Mendelian randomization study
Yuan S; Carter P; Bruzelius M; Vithayathil M; Kar S; Mason AM; Lin A; Burgess S; Larsson SC
Journal article: JOURNAL OF AMERICAN COLLEGE HEALTH. 2020;68(6):587-592
The impact of a health education intervention on health behaviors and mental health among Chinese college students
Yang X-H; Yu H-J; Liu M-W; Zhang J; Tang B-W; Yuan S; Gasevic D; Paul K; Wang P-G; He Q-Q
Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2020;313:99-104
Circulating interleukins in relation to coronary artery disease, atrial fibrillation and ischemic stroke and its subtypes: A two-sample Mendelian randomization study
Yuan S; Lin A; He Q-Q; Burgess S; Larsson SC
Article: SCIENTIFIC REPORTS. 2020;10(1):13807
Associations of cigarette smoking with psychiatric disorders: evidence from a two-sample Mendelian randomization study
Yuan S; Yao H; Larsson SC
Journal article: INTERNATIONAL JOURNAL OF BEHAVIORAL MEDICINE. 2020;27(4):400-405
Association of Adverse Childhood Experiences with Health Risk Behaviors Among College Students in Zambia.
Zhang J; Tang B-W; Liu M-W; Yuan S; Yu H-J; Zhang R; Huang X-C; Nzala SH; Chikoya M; Wang P-G; He Q-Q
Article: CLINICAL NUTRITION. 2020;39(7):2180-2186
Plasma phospholipid fatty acids, bone mineral density and fracture risk: Evidence from a Mendelian randomization study
Yuan S; Lemming EW; Michaelsson K; Larsson SC
Article: DIABETES. 2020;69(7):1588-1596
Is Type 2 Diabetes Causally Associated With Cancer Risk? Evidence From a Two-Sample Mendelian Randomization Study
Yuan S; Kar S; Carter P; Vithayathil M; Mason AM; Burgess S; Larsson SC
Article: DIABETOLOGIA. 2020;63(7):1305-1311
Major depressive disorder and cardiometabolic diseases: a bidirectional Mendelian randomisation study
Tang B; Yuan S; Xiong Y; He Q; Larsson SC
Article: NUTRIENTS. 2020;12(2):E526-526
Iron Status and Cancer Risk in UK Biobank: A Two-Sample Mendelian Randomization Study
Yuan S; Carter P; Vithayathil M; Kar S; Giovannucci E; Mason AM; Burgess S; Larsson SC
Article: AMERICAN JOURNAL OF PREVENTIVE MEDICINE. 2020;58(2):294-301
Fat Intake and Hypertension Among Adults in China: The Modifying Effects of Fruit and Vegetable Intake
Yuan S; Yu H-J; Liu M-W; Tang B-W; Zhang J; Gasevic D; Larsson SC; He Q-Q
Article: NUTRIENTS. 2020;12(1):E194-194
Improving the Metabolic and Mental Health of Children with Obesity: A School-Based Nutrition Education and Physical Activity Intervention in Wuhan, China
Yu H-J; Li F; Hu Y-F; Li C-F; Yuan S; Song Y; Zheng M; Gong J; He Q-Q
Article: DIABETOLOGIA. 2020;63(1):116-123
Association of genetic variants related to plasma fatty acids with type 2 diabetes mellitus and glycaemic traits: a Mendelian randomisation study
Yuan S; Larsson SC
Article: SCIENTIFIC REPORTS. 2019;9(1):19342
A causal relationship between cigarette smoking and type 2 diabetes mellitus: A Mendelian randomization study
Yuan S; Larsson SC
Article: NUTRIENTS. 2019;11(12):E3001-3001
Plasma Phospholipid Fatty Acids, FADS1 and Risk of 15 Cardiovascular Diseases: A Mendelian Randomisation Study
Yuan S; Back M; Bruzelius M; Mason AM; Burgess S; Larsson S
Article: DIABETES CARE. 2019;42(12):2197-2203
Genetic Prediction of Serum 25-Hydroxyvitamin D, Calcium, and Parathyroid Hormone Levels in Relation to Development of Type 2 Diabetes: A Mendelian Randomization Study
Yuan S; Jiang X; Michaelsson K; Larsson SC
Article: CALCIFIED TISSUE INTERNATIONAL. 2019;105(6):582-588
Associations of Smoking and Alcohol and Coffee Intake with Fracture and Bone Mineral Density: A Mendelian Randomization Study
Yuan S; Michaelsson K; Wan Z; Larsson SC
Article: NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES. 2019;29(11):1185-1188
No association between coffee consumption and risk of atrial fibrillation: A Mendelian randomization study
Yuan S; Larsson SC
Journal article: JOURNAL OF MICROENCAPSULATION. 2019;36(7):649-658
One-step microencapsulation and spraying of pesticide formulations for improved adhesion and sustained release
Zhang M; Zhu Z; Yuan S; Wang S; Yang C; Dwivedi P; Si T; Xu RX
Journal article: ARCHIVES OF SEXUAL BEHAVIOR. 2019;48(7):2117-2123
Risky Sexual Behaviors and Associated Factors Among College Students in Lusaka, Zambia
Yang X-H; Yuan S; Zhang R; Yu J-F; Nzala SH; Wang P-G; He Q-Q
Article: NUTRIENTS. 2019;11(7):E1651-1651
Plasma Phospholipid Fatty Acids and Risk of Atrial Fibrillation: A Mendelian Randomization Study
Yuan S; Larsson SC
Journal article: JOURNAL OF PUBLIC HEALTH. 2019;41(2):E169-E176
Cigarette smoking as a risk factor for type 2 diabetes in women compared with men: a systematic review and meta-analysis of prospective cohort studies
Yuan S; Xue H-L; Yu H-J; Huang Y; Tang B-W; Yang X-H; Li Q-X; He Q-Q
Journal article: JOURNAL OF AFFECTIVE DISORDERS. 2019;252:278-293
How does childhood maltreatment influence ensuing cognitive functioning among people with the exposure of childhood maltreatment? A systematic review of prospective cohort studies
Su Y; D'Arcy C; Yuan S; Meng X
Journal article: MOLECULAR PHARMACOLOGY. 2019;95(6):629-637
Antagonism of Forkhead Box Subclass O Transcription Factors Elicits Loss of Soluble Guanylyl Cyclase Expression
Galley JC; Durgin BG; Miller MP; Hahn SA; Yuan S; Wood KC; Straub AC
Journal article: ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY. 2018;46(sup3):S481-S491
Core-shell microencapsulation of curcumin in PLGA microparticles: programmed for application in ovarian cancer therapy
Dwivedi P; Yuan S; Han S; Mangrio FA; Zhu Z; Lei F; Ming Z; Cheng L; Liu Z; Si T; Xu RX
Journal article: EUROPEAN JOURNAL OF NUTRITION. 2018;57(7):2639-2647
Association between fruit and vegetable intake and the risk of hypertension among Chinese adults: a longitudinal study
Liu M-W; Yu H-J; Yuan S; Song Y; Tang B-W; Cao Z-K; Yang X-H; Towne SDJ; He Q-Q
Journal article: JOURNAL OF PEDIATRICS. 2018;200:150-154.e1
Cardiorespiratory Fitness Attenuates the Obesity Risk in Chinese Children Who Have Parents with Overweight/Obesity
Yu H-J; Cai L-B; Yang X-H; Yuan S; Li Q-X; He Q-Q
Journal article: BMC PUBLIC HEALTH. 2018;18(1):986
Associations of physical activity and fruit and vegetable intake with well-being and depressive symptoms among obese schoolchildren in Wuhan, China: a cross-sectional study
Yu H-J; Li F; Hu Y-F; Li C-F; Yang X-H; Yuan S; Huang Y; Tang B-W; Gong J; He Q-Q
Journal article: PUBLIC HEALTH. 2018;157:121-126
The association of fruit and vegetable consumption with changes in weight and body mass index in Chinese adults: a cohort study
Yuan S; Yu HJ; Liu MW; Huang Y; Yang XH; Tang BW; Song Y; Cao ZK; Wu HJ; He QQ; Gasevic D
Journal article: JOURNAL OF IMMUNOLOGY. 2017;199(12):3991-4000
The Type 1 Diabetes-Resistance Locus Idd22 Controls Trafficking of Autoreactive CTLs into the Pancreatic Islets of NOD Mice
Whitener RL; Knight LG; Li J; Knapp S; Zhang S; Annamalai M; Pliner VM; Fu D; Radichev I; Amatya C; Savinov A; Yurdagul AJ; Yuan S; Glawe J; Kevil CG; Chen J; Stimpson SE; Mathews CE
Journal article: PLOS ONE. 2017;12(11):e0188533
Combined effects of fruit and vegetables intake and physical activity on the risk of metabolic syndrome among Chinese adults
Li X-T; Liao W; Yu H-J; Liu M-W; Yuan S; Tang B-W; Yang X-H; Song Y; Huang Y; Cheng S-L; Chen Z-Y; Towne SDJ; Mao Z-F; He Q-Q
Journal article: ANTIOXIDANTS & REDOX SIGNALING. 2017;27(10):634-653
Beyond a Gasotransmitter: Hydrogen Sulfide and Polysulfide in Cardiovascular Health and Immune Response
Yuan S; Shen X; Kevil CG
Journal article: PUBLIC HEALTH. 2017;149:65-70
Association between obesity phenotypes and incident hypertension among Chinese adults: a prospective cohort study
Cao ZK; Huang Y; Yu HJ; Yuan S; Tang BW; Li QX; Li XT; Yang XH; He QQ
Journal article: MOLECULAR NUTRITION & FOOD RESEARCH. 2017;61(6)
Dietary total flavonoids intake and risk of mortality from all causes and cardiovascular disease in the general population: A systematic review and meta-analysis of cohort studies
Liu X-M; Liu Y-J; Huang Y; Yu H-J; Yuan S; Tang B-W; Wang P-G; He Q-Q
Journal article: ANTIOXIDANTS & REDOX SIGNALING. 2017;26(16):936-960
Gasotransmitter Heterocellular Signaling
Kolluru GK; Shen X; Yuan S; Kevil CG
Journal article: JOURNAL OF CHILD AND FAMILY STUDIES. 2017;26(5):1380-1387
Association between Child Abuse and Health Risk Behaviors among Chinese College Students
Chen Y-L; Liu X; Huang Y; Yu H-J; Yuan S; Ye Y-L; Li Q-X; He Q-Q
Journal article: SCIENTIFIC REPORTS. 2017;7:44908
Ultrasound mediated delivery of oxygen and LLL12 loaded stimuli responsive microdroplets for the treatment of hypoxic cancer cells
Xu J; Yuan S; Tian J; Martin KA; Song J; Li C; Wang Z; Lin J; Si T; Xu RX
Journal article: REDOX BIOLOGY. 2016;9:157-166
Hydrogen sulfide metabolism regulates endothelial solute barrier function
Yuan S; Pardue S; Shen X; Alexander JS; Orr AW; Kevil CG
Journal article: MATERNAL AND CHILD HEALTH JOURNAL. 2016;20(9):1904-1910
Combined Association of Diet and Cardiorespiratory Fitness with Metabolic Syndrome in Chinese Schoolchildren
Liao W; Xiao D-M; Huang Y; Yu H-J; Yuan S; Chen T; Phongsavan P; Mao Z-F; He Q-Q
Journal article: PSYCHOLOGY HEALTH & MEDICINE. 2016;21(3):377-385
Associations between multiple health risk behaviors and mental health among Chinese college students
Ye Y-L; Wang P-G; Qu G-C; Yuan S; Phongsavan P; He Q-Q
Journal article: MICROCIRCULATION. 2016;23(2):134-145
Nitric Oxide and Hydrogen Sulfide Regulation of Ischemic Vascular Remodeling
Yuan S; Kevil CG
Journal article: CARDIOVASCULAR RESEARCH. 2015;107(4):590-600
Cystathionine γ-lyase regulates arteriogenesis through NO-dependent monocyte recruitment
Kolluru GK; Bir SC; Yuan S; Shen X; Pardue S; Wang R; Kevil CG
Journal article: JOURNAL OF MATERIALS RESEARCH. 2015;30(16):2434-2446
Zeolite-zeolite composite fabricated by polycrystalline Y zeolite crystals parasitizing ZSM-5 zeolite
Wang G; Liu Y; Zheng J; Pan M; Zhang H; Li B; Yuan S; Yi Y; Tian H; Li R
Journal article: PLOS ONE. 2015;10(8):e0135608
Coaxial Electrospray of Ranibizumab-Loaded Microparticles for Sustained Release of Anti-VEGF Therapies
Zhang L; Si T; Fischer AJ; Letson A; Yuan S; Roberts CJ; Xu RX
Journal article: PLOS ONE. 2015;10(7):e0132609
Coaxial Electrospray of Curcumin-Loaded Microparticles for Sustained Drug Release
Yuan S; Lei F; Liu Z; Tong Q; Si T; Xu RX
Journal article: AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY. 2015;308(5):L403-L415
Working with nitric oxide and hydrogen sulfide in biological systems
Yuan S; Patel RP; Kevil CG
Journal article: PLOS ONE. 2015;10(2):e0117982
Role of Hydrogen Sulfide in Early Blood-Brain Barrier Disruption following Transient Focal Cerebral Ischemia
Jiang Z; Li C; Manuel ML; Yuan S; Kevil CG; McCarter KD; Lu W; Sun H
Journal article: PREVENTING CHRONIC DISEASE. 2015;12:E01
Parental Weight Status and Offspring Cardiovascular Disease Risks: a Cross-Sectional Study of Chinese Children
McCarthy K; Ye Y-L; Yuan S; He Q-Q
Journal article: RECOMBINANT PROTEIN EXPRESSION: PROKARYOTIC HOSTS AND CELL-FREE SYSTEMS. 2015;554:271-297
H₂S Regulation of Nitric Oxide Metabolism
Kolluru GK; Yuan S; Shen X; Kevil CG
Journal article: RECOMBINANT PROTEIN EXPRESSION: PROKARYOTIC HOSTS AND CELL-FREE SYSTEMS. 2015;554:31-45
Measurement of H₂S In Vivo and In Vitro by the Monobromobimane Method
Shen X; Kolluru GK; Yuan S; Kevil CG
Journal article: STATISTICS IN MEDICINE. 2012;31(29):3789-3804
Variable selection for covariate-adjusted semiparametric inference in randomized clinical trials
Yuan S; Zhang HH; Davidian M
Journal article:
Mendelian Randomization Analysis Revealed Pan-Effect of Smoking Instead of Alcohol Consumption on 24 Gastrointestinal Diseases
Yuan S; Chen J; Ruan X; Sun Y; Zhang K; Wang X; Li X; Gill D; Burgess S; Giovannucci E; Larsson S
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Preprint: MEDRXIV. 2026;MEDRXIV
Decoding the genetic architecture of hernia through genome-wide association and multi-trait analyses.
Pregnall AM; Yuan S; Lawrence JM; Abramowitz SA; DePaolo J; Judy R; Shakt G; Levin MG; Damrauer SM; Wachtel H
Preprint: MEDRXIV. 2026
Comparative genomic analysis reveals shared and distinct mechanisms of nasal polyps and chronic rhinosinusitis
Yuan S; McVey JC; Hartmann K; Abramowitz S; Woerner J; Shakt G; Judy R; Douglas JE; Voight BF; Kohanski MA; Cohen NA; Levin MG; Damrauer SM
Review: HEART. 2026;:heartjnl-2025-326870
Atrial fibrillation: genetic architecture and polygenic risk prediction
Yuan S; Levin MG; Larsson SC
Preprint: MEDRXIV. 2026;MEDRXIV
Triglyceride-rich lipoproteins, low-density lipoproteins, and risk of abdominal aortic aneurysm.
Yuan S; Björnson E; Shakt G; Dinatale T; Lynch JA; Temel RE; Lu HS; Daugherty A; VA Million Veteran Program; Chang K-M; Tsao P; Adkar S; Levin MG; Damrauer SM; Leeper NJ
Preprint: MEDRXIV. 2026;MEDRXIV
Integrated metabolomics and genetic analyses reveal loss of protective docosahexaenoic acid as a key driver linking ultra-processed food to Crohn's disease risk.
Wang S; Dan L; Ruan X; Wellens J; Sun Y; Yao J; Tian L; Kalla R; Theodoratou E; Yuan S; Larsson SC; Ludvigsson JF; Peyrin-Biroulet L; Satsangi J; Magro F; Li X; Wang X; Chen J
Preprint: MEDRXIV. 2026;MEDRXIV
Epigenetics in Abdominal Aortic Aneurysm: Mechanisms and Risk Prediction.
Yuan S; Shakt G; Levin MG; Hartmann K; Judy R; Dinatale T; Voorhees A; Lynch JA; Pyarajan S; Levy D; Joehanes R; VA Million Veteran Program; Chang K-M; Tsao P; Voight BF; Jones GT; Damrauer SM
Editorial: CLINICAL EPIDEMIOLOGY. 2025;17:481-484
Celiac Disease and Incident Dupuytren's Contracture: A Matched Nationwide Cohort Analysis
Yuan S; Furniss D; Larsson SC; Leffler DA; Ludvigsson JF; Yuan S
Conference publication: CIRCULATION. 2025;152(SUPPL_3):a4367273
Abstract 4367273: Epigenetic Architecture of Abdominal Aortic Aneurysm and Its Augmented Risk in Smokers: Insights from Methylome-Genome Integration
Yuan S; Shakt G; Hartmann K; Levin M; Tsao P; Voight B; Jones G; Damrauer S
Letter: CIRCULATION. 2025;152(14):1034-1036
Self-Reported Race as a Determinant of Differential Methylation in Peripheral Artery Disease
Stolze LK; Sullivan AE; Wang Y; Behroozian A; Yuan S; Damrauer SM; Sheng Q; Beckman JA; Brown JD
Corrigendum: NATURE COMMUNICATIONS. 2025;16(1):8811
Cross-population GWAS and proteomics improve risk prediction and reveal mechanisms in atrial fibrillation (vol 16, 6426, 2025)
Yuan S; Chen J; Ruan X; Li Y; Abramowitz SA; Wang L; Jiang F; Xiong Y; Levin MG; Voight BF; Gill D; Burgess S; Akesson A; Michaelsson K; Li X; Damrauer SM; Larsson SC
Review: JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. 2025;40(10):2391-2401
Helicobacter pylori Infection and Eradication in Relation to Gastroesophageal Reflux Disease
Wang H; Qu Y; Lin Y; Liu Z; Lagergren J; Yuan S; Ness-Jensen E; Jiang W; Xie S-H
Editorial: EUROPEAN HEART JOURNAL. 2025;46(35):3502-3503
Circulating proteins and incident myocardial infarction: appraising sex-specific differences and causality
Titova OE; Yuan S; Byberg L; Baron JA; Lind L; Michaelsson K; Larsson SC
Review: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2025;45(9):1493-1504
Alcohol, Liver Disease, and Peripheral Arterial Disease: Epidemiology, Mechanisms, and Clinical Implications
Yuan S; Damrauer SM; Larsson SC
Editorial: EUROPEAN HEART JOURNAL. 2025;46(29):2930
Applying Mendelian randomization to study the relationship between circulating proteins and myocardial infarction
Titova OE; Yuan S; Larsson SC
Review: HUMAN REPRODUCTION UPDATE. 2025;31(3):240-268
Harnessing omics data for drug discovery and development in ovarian aging
Zhang F; Zhu M; Chen Y; Wang G; Yang H; Lu X; Li Y; Chang H-M; Wu Y; Ma Y; Yuan S; Zhu W; Dong X; Zhao Y; Yu Y; Wang J; Mu L
Review: NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY. 2025;22(4):252-264
Coeliac disease: complications and comorbidities
Ludvigsson JF; Yao J; Lebwohl B; Green PHR; Yuan S; Leffler DA
Preprint: MEDRXIV. 2025;MEDRXIV
Identifying Circulating Protein Mediators in the Link Between Smoking and Abdominal Aortic Aneurysm: An Integrated Analysis of Human Proteomic and Genomic Data.
Yuan S; Khodursky S; Geng J; Sharma P; Spin JM; Tsao P; Levin MG; Damrauer SM
Letter: GUT. 2024;74(1):e6
Concerns about instrumental variable selection for biological effect versus uptake of proton pump inhibitors in Mendelian randomisation analysis
Yuan S; Larsson SC; Gill D; Burgess S
Letter: FERTILITY AND STERILITY. 2024;122(6):1144-1146
No association between celiac disease and female infertility: evidence from Mendelian randomization analysis
Yuan S; Chen J; Li X; Lef DA; Larsson SC; Ludvigsson JF
Letter: FERTILITY AND STERILITY. 2024;122(6):1166
Reply of the authors: no association between celiac disease and female infertility: evidence from Mendelian randomization analysis
Yuan S; Ludvigsson JF
Conference publication: CIRCULATION. 2024;150:a4129533
Phenotypes and clinical outcome of heart failure with preserved ejection fraction (HFpEF) patients in China: Findings from the Chinese Cardiovascular Association Database-Heart Failure Center Registry
Yuan S; Xie Z; Cui X; Zhou J; Ge J
Conference publication: CIRCULATION. 2024;150:a4138067
Prognostic effect of echocardiography-assessed coronary flow reserve in heart failure with preserved ejection fraction
Cui X; Wang Y; Liu D; Xu Y; Zhao Y; Song Y; Han X; Yuan S; Yao S; Yu X; Xie Z; Wang Z; Chen H; Shu XH; Hu K; Zhou J; Ge J
Conference publication: CIRCULATION. 2024;150:a4146394
Plasma proteomics reveals the potential causal impact of ECM proteins on abdominal aortic aneurysm
Khodursky S; Yuan S; Spin J; Tsao P; Levin M; Damrauer S
Conference publication: CIRCULATION. 2024;150:a4144876
Genetic evaluation of metabolic signatures associated with lipidlowering medications
Sharma P; Khodursky S; Yuan S; Damrauer S; Levin M
Conference publication: CIRCULATION. 2024;150:a4146208
Blood protein mediators of association between smoking and abdominal aortic aneurysm: exploration integrating human proteomic and genomic data
Yuan S; Khodursky S; Geng J; Sharma P; Spin J; Tsao P; Levin M; Damrauer S
Conference publication: JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. 2024;39:106-107
Dietary antioxidant capacity, genetic susceptibility and polymorphism, and risk of Crohn's disease and ulcerative colitis
Chen J; Dan L; Yuan S; Fu T; Sun J; Alicja W; Jonas L; Li X; Wang X; Susanna L
Conference publication: JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. 2024;39:89-90
Multisystem health comorbidity networks of metabolic dysfunction-associated steatotic liver disease
Jiang F; Wang L; Ying H; Sun J; Zhao J; Lu Y; Bian Z; Chen J; Fang A; Zhang X; Larsson SC; Mantzoros CS; Wang W; Yuan S; Ding Y; Li X
Conference publication: JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. 2024;39:311-312
Plant-based diets mitigate the incidence risk, disease course and comorbidity of inflammatory bowel disease
Chen J; Sun Y; Dan L; Wellens J; Yuan S; Yang H; Tong T; Cross A; Papadimitriou N; Meyer A; Dahm C; Larsson S; Wolk A; Ludvigsson J; Tsilidis K; Giovannucci E; Satsangi J; Wang X; Theodoratou E; Chan S; Li X
Letter: FERTILITY AND STERILITY. 2024;122(5):960-961
Reply of the authors: a commentary on: "Association of serum uric acid with women's ovarian reserve: observational study and Mendelian randomization analyses"
Wang G; Yang H; Jiang X; Mao W; Li P; Lin X; Li Y; Ye Z; Zhang Y; Chen W; Yuan S; Zhao Y; Mu L
Preprint: MEDRXIV. 2024
Proteome-wide and mendelian randomisation analyses of chronic widespread pain: diagnosis, prognosis, and drug target discovery
Chen L; Kelleher E; Meng R; Liu D; Guo Y; Wang Y; Gao Y; Huang Z; Liang Z; Yuan S; Zeng C; Lei G; Ma J; Dong Y; Irani A; Xie J; Prieto-Alhambra D
Preprint: MEDRXIV. 2024;MEDRXIV
Plasma proteomics reveals the potential causal impact of extracellular matrix proteins on abdominal aortic aneurysm.
Khodursky S; Yuan S; Spin JM; Tsao PS; Levin MG; Damrauer SM
Preprint: MEDRXIV. 2024;MEDRXIV
Lipoprotein (a) is associated with increased risk of Abdominal Aortic Aneurysm.
Sharma P; Judy R; Yuan S; Gellatly C; Saxby KL; Bown MJ; Levin MG; Damrauer SM
Review: ENDOCRINE REVIEWS. 2024;45(4):437-459
Genetic and Epigenetic Landscape for Drug Development in Polycystic Ovary Syndrome
Chen Y; Wang G; Chen J; Wang C; Dong X; Chang H-M; Yuan S; Zhao Y; Mu L
Review: EGASTROENTEROLOGY. 2024;2(2):e100058
Mendelian randomisation analysis for intestinal disease: achievement and future
Ruan X; Che T; Chen X; Sun Y; Fu T; Yuan S; Li X; Chen J; Wang X
Conference publication: GASTROENTEROLOGY. 2024;166(5):S736-S737
PHENOME-WIDE MENDELIAN RANDOMIZATION ANALYSIS REVEALS MULTIPLE HEALTH COMORBIDITIES OF CELIAC DISEASE
Yuan S; Jiang F; Chen J; Lebwohl B; Green PH; Leffler DA; Larsson SC; Li X; Ludvigsson J
Conference publication: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2024;44:a2109
Nox1-mediated Endothelial Ros Propagates Hypoxia-induced Pulmonary Hypertension Via The Unfolded Protein Response
Goossen CJ; Kracun D; Pagano PJ; Straub AC; Gomez DA; Al Ghouleh I; Dustin C; Cifuentes-Pagano E; Yuan S
Preprint: MEDRXIV. 2024
Modifiable risk factors and inflammation-related proteins in polymyalgia rheumatica: genome-wide meta-analysis and Mendelian randomisation
Zhao SS; Mackie S; Larsson S; Burgess S; Yuan S
Letter: GUT. 2024;73(5):878-879
Defining gene-lifestyle interactions in inflammatory bowel disease: progress towards understanding disease pathogenesis
Zhao J; Chen J; Sun Y; Yuan S; Wellens J; Kalla R; Theodoratou E; Li X; Satsangi J
Preprint: RESEARCH SQUARE. 2024
Novel genetic loci, lifestyle factors, and inflammatory markers identified as risk factors for sarcoidosis
Yuan S; Chen J; Zhao SS; Yarmolinsky J; Arkema E; Tsilidis K; Burgess S; Larsson S
Doctoral thesis: 2024
Modifiable risk factors, blood proteins, and venous thromboembolism
Yuan S
Preprint: RESEARCH SQUARE. 2023
Dose Stasis Impact Venous Thrombosis via Hypercoagulability? Evidence from Multivariable Mendelian Randomization Analysis
Yuan S; Wiggins KL; Xiong Y; Smith NL; Damrauer SM; Larsson SC
Preprint: MEDRXIV. 2023;MEDRXIV
Deciphering the genetic architecture of atrial fibrillation offers insights into disease prediction, pathophysiology and downstream sequelae.
Yuan S; Li Y; Wang L; Xu F; Chen J; Levin MG; Xiong Y; Voight BF; Damrauer SM; Gill D; Burgess S; Åkesson A; Michaëlsson K; Li X; Shen X; Larsson SC
Letter: METABOLISM-CLINICAL AND EXPERIMENTAL. 2023;144:155560
Clarity and quality assessment of epidemiology of sarcopenia: Prevalence, risk factors, and consequences Response
Yuan S; Larsson SC
Review: METABOLISM-CLINICAL AND EXPERIMENTAL. 2023;144:155533
Epidemiology of sarcopenia: Prevalence, risk factors, and consequences
Yuan S; Larsson SC
Conference publication: GUT. 2023;72(SUPPL_2):A56-A57
Multisystem health consequences of nonalcoholic fatty liver disease: phenome-wide Mendelian randomization and disease-trajectory analyses
Jiang F; Wang L; Ding Y; Lu MY; Sun J; Zhao J; Chen J; Larsson S; Wang W; Yuan S; Li X
Conference publication: GUT. 2023;72(SUPPL_2):A26
Identification of novel protein biomarkers and drug targets for colorectal cancer by integrating human plasma proteome with genome
Sun J; Zhao J; Xiao Q; Han F; Yuan S; Wei J; Larsson SC; Zhang H; Dunlop M; Farrington SM; Ding K-F; Theodoratou E; Li X
Letter: ALIMENTARY PHARMACOLOGY & THERAPEUTICS. 2023;57(9):1048-1049
Letter: disentangling the role of redox-active compounds in the development of inflammatory bowel diseases-moving towards causal associations. Authors' reply
Chen J; Ruan X; Yuan S; Theodoratou E; Satsangi J; Li X
Conference publication: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2023;43
Spatially Resolved Metabolites In Stable And Unstable Human Atherosclerotic Plaques Identified By Mass Spectrometry Imaging
Seeley E; Liu Z; Yuan S; Stroope C; Cockerham E; Rashdan N; Delgadillo L; Finney A; Kumar D; Das S; Razani B; Liu W; Rom O; Pattillo CB; Yurdagul A
Editorial: ALIMENTARY PHARMACOLOGY & THERAPEUTICS. 2023;57(9):1034-1035
Editorial: in search of environmental risk factors of Crohn's disease and ulcerative colitis with mendelian randomisation-authors' reply
Chen J; Ruan X; Yuan S; Theodoratou E; Satsangi J; Li X
Review: DIABETOLOGIA. 2023;66(5):800-812
Causal factors underlying diabetes risk informed by Mendelian randomisation analysis: evidence, opportunities and challenges
Yuan S; Merino J; Larsson SC
Preprint: BIORXIV. 2023
Apolipoprotein B and Interleukin 1 Receptor Antagonist: Reversing the Risk of Coronary Heart Disease
Yang F; Huangfu N; Shen J; Su P; Zhu L; Cui H; Yuan S
Preprint: MEDRXIV. 2023
Risk of incident cardiovascular disease among patients with gastrointestinal disorder: prospective cohort study of 340,862 individuals
Chen J; Sun Y; Fu T; Lu S; Shi W; Zhao J; Li S; Li X; Yuan S; Larsson S
Preprint: MEDRXIV. 2023
Sedentary lifestyle, Physical Activity, and Gastrointestinal Diseases: Evidence from Mendelian Randomization Analysis
Chen J; Ruan X; Fu T; Lu S; Gill D; He Z; Burgess S; Giovannucci E; Larsson S; Deng M; Yuan S; Li X
Editorial: ALIMENTARY PHARMACOLOGY & THERAPEUTICS. 2023;57(5):575-576
Editorial: IBD and sleep-authors' reply
Yuan S; Chen J; Li X
Preprint: RESEARCH SQUARE. 2022
Identification of novel protein biomarkers and drug targets for colorectal cancer by integrating human plasma proteome with genome
Sun J; Zhao J; Jiang F; Wang L; Xiao Q; Han F; Chen J; Yuan S; Wei J; Larsson S; Honghe Z; Dunlop M; Farrington S; Ding K; Theodoratou E; Li X
Preprint: MEDRXIV. 2022
Birthweight, Childhood Obesity, Adulthood Obesity and Body Compositions, and Gastrointestinal Diseases: A Mendelian Randomization Study
Yuan S; Ruan X; Sun Y; Fu T; Zhao J; Deng M; Chen J; Li X; Larsson SC
Letter: FERTILITY AND STERILITY. 2022;118(6):1203-1204
Reply of the Authors: Smoking, alcohol, and coffee consumption and pregnancy loss: a Mendelian randomization investigation
Yuan S; Liu J; Larsson SC
Preprint: MEDRXIV. 2022
Gastrointestinal Diseases, Genetic Risk, and Incident Dementia: A Prospective Cohort Study in 352,463 Middle-Aged Adults
Yuan S; Dan L; Zhang Y; Wu J; Zhao J; Chen J; Li X; Kivipelto M; Larsson S
Conference publication: CIRCULATION. 2022;146
Sleep Duration, Quality, and Risk of Peripheral Artery Disease: Multinational Cohort and Mendelian Randomization Studies
Yuan S; Levin MG; Titova O; Chen J; Sun Y; Program VAMV; Akesson A; Li X; Damrauer SM; Larsson S
Preprint: RESEARCH SQUARE. 2022
Depression and 24 Gastrointestinal Diseases: A Mendelian Randomization Study
Yuan S; Ruan X; Chen J; Sun Y; Zhang Y; Zhao J; Wang X; Li X; Larsson S
Conference publication: EUROPEAN HEART JOURNAL. 2022;43:2432
Selenium concentration and cardiovascular disease risk: Mendelian randomization study
Yuan S; Mason AM; Bruzelius M; Akesson A; Burgess S; Larsson SC
Letter: CIRCULATION-GENOMIC AND PRECISION MEDICINE. 2022;15(5):e003830-475
Anthropometric Traits and Risk of Mitral Valve Prolapse: A Mendelian Randomization Study
Yuan S; Karhunen V; Larsson S; Gill D
Preprint: MEDRXIV. 2022
The contribution of genetic risk and lifestyle factors in the development of adult-onset inflammatory bowel disease: a prospective cohort study
Sun Y; Yuan S; Chen X; Sun J; Kalla R; Yu L; Wang L; Zhou X; Kong X; Hesketh T; Ho G-T; Ding K; Dunlop M; Larsson S; Satsangi J; Chen J; Wang X; Li X; Theodoratou E; Giovannucci E
Review: AMERICAN JOURNAL OF CLINICAL NUTRITION. 2022;116(1):230-243
Gut microbiota-derived metabolite trimethylamine-N-oxide and multiple health outcomes: an umbrella review and updated meta-analysis
Li D; Lu Y; Yuan S; Cai X; He Y; Chen J; Wu Q; He D; Fang A; Bo Y; Song P; Bogaert D; Tsilidis K; Larsson SC; Yu H; Zhu H; Theodoratou E; Zhu Y; Li X
Preprint: MEDRXIV. 2022
Sleep Duration, Quality, and Risk of Peripheral Artery Disease: Multinational Cohort and Mendelian Randomization Studies
Yuan S; Levin M; Titova O; Chen J; Sun Y; VA Million Veteran Program; Åkesson A; Li X; Damrauer S; Larsson S
Letter: EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY. 2022;29(1):e29-e31
Coffee consumption and risk of coronary artery disease
Zhang Z; Wang M; Yuan S; Liu X
Preprint: SSRN ELECTRONIC JOURNAL. 2022
Genetically Predicted High IGF-1 Levels Showed Protective Effects on COVID-19 Susceptibility and Hospitalization: A Mendelian Randomisation Study with Data from 60 Studies Across 25 Countries
Li X; Zhou Y; Yuan S; Zhou X; Wang L; Sun J; Yu L; Zhu J; Zhang H; Yang N; Dai S; Song P; Larsson S; Zhu Y; Li X; Theodoratou E
Preprint: SSRN ELECTRONIC JOURNAL. 2022
Mendelian Randomization Analysis Revealed Pan-Effect of Smoking Instead of Alcohol Consumption on 24 Gastrointestinal Diseases
Yuan S; Chen J; Ruan X; Sun Y; Zhang K; Wang X; Li X; Gill D; Burgess S; Giovannucci E; Larsson S
Preprint: BIORXIV. 2021
Cooperation between CYB5R3 and NOX4 via coenzyme Q mitigates endothelial inflammation
Yuan S; Hahn S; Miller M; Sanker S; Calderon M; Sullivan M; Dosunmu-Ogunbi A; Fazzari M; Li Y; Reynolds M; Wood K; St. Croix C; Stolz D; Cifuentes-Pagano E; Navas P; Shiva S; Schopfer F; Pagano P; Straub A
Letter: ALLERGY. 2021;76(5):1559-1562
Assessing the protective role of allergic disease in gastrointestinal tract cancers using Mendelian randomization analysis
Yuan S; Vithayathil M; Kar S; Carter P; Mason AM; Xie S-H; Burgess S; Larsson SC
Preprint: SSRN ELECTRONIC JOURNAL. 2021
Association of Food Expenditure with Life Expectancy in the United States, 2001- 2014
Li Q; Yuan S; Yu Z; Larsson S; He Q
Review: SAO PAULO MEDICAL JOURNAL. 2020;138(5):393-399
Can p63 serve as a biomarker for diagnosing giant cell tumor of bone? A systematic review and meta-analysis
Wan Z; Lee C-W; Yuan S; Lee OK-S
Preprint: MEDRXIV. 2020
Causal associations between salt intake with body mass, shape and composition: A two-sample Mendelian randomization study
Feng Q; Yuan S; Yang Q; Lu Y; Loos RJF; Li GHY; Fei Y; Tsoi MF; Cheung CL; Cheung BMY
Conference publication: JACC-JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 2020;75(11):694
ONG NON-CODING RNA RP11-96L14.7 ALLEVIATES HEART FAILURE BY INCREASING HNRNPC-MEDIATED RYR2 MRNA STABILITY
Chen C; Yuan S; Fan J; Wang DW
Preprint: MEDRXIV. 2020
Health-related effects of education level: a Mendelian randomization study
Yuan S; Xiong Y; Michaëlsson M; Michaëlsson K; Larsson S
Conference publication: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2018;38(9):2126-2136
Cystathionine -Lyase Modulates Flow-Dependent Vascular Remodeling
Yuan S; Yurdagul AJ; Peretik JM; Alfaidi M; Al Yafeai Z; Pardue S; Kevil CG; Orr AW
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From Normal Abdominal Aorta to Aneurysms: Unpacking Genetic Uniqueness and Refining Risk Prediction
American Heart Association
1 June 2024 - 31 May 2026

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Anknuten till Forskning, Institutet för miljömedicin, Karolinska Institutet, 2024-2027
Anknuten till Forskning, Medicinsk epidemiologi och biostatistik, Karolinska Institutet, 2024-2026

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Medicine Doktorsexamen, Institutet för miljömedicin, Karolinska Institutet, 2024
Medicine Masterexamen, Karolinska Institutet, 2020

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