Shuai Yuan

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About me

I work at the Unit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine in Karolinska Institutet. I am interested in investigating the associations of lifestyle factors and nutrition with cardiometabolic and gastrointestinal diseases by using epidemiological and genetic approaches.

Research

• Investigating the associations of lifestyle and nutritional factors with cardiometabolic and gastrointestinal disease.
• Identifying protein biomarkers and drug targets for common diseases by integrating human plasma proteome with genome.
• Genome-wide association analysis and subsequent genetic analysis on cardiometabolic and gastrointestinal disease.

Articles

Journal article: EBIOMEDICINE. 2024;110:105443
Exposure to air pollution increases susceptibility to ulcerative colitis through epigenetic alterations in CXCR2 and MHC class III region
Chen J; Zhang H; Fu T; Zhao J; Nowak JK; Kalla R; Wellens J; Yuan S; Noble A; Ventham NT; Dunlop MG; Halfvarson J; Mao R; Theodoratou E; Satsangi J; Li X
Article: FERTILITY AND STERILITY. 2024;122(6):1144-1146
No association between celiac disease and female infertility: evidence from Mendelian randomization analysis
Yuan S; Chen J; Li X; Lef DA; Larsson SC; Ludvigsson JF
Article: EUROPEAN HEART JOURNAL. 2024;45(43):4647-4657
Plasma proteome and incident myocardial infarction: sex-specific differences
Titova OE; Yuan S; Byberg L; Baron JA; Lind L; Michaelsson K; Larsson SC
Article: MED. 2024;5(11):1413-1423.e3
Multisystem health comorbidity networks of metabolic dysfunction-associated steatotic liver disease
Jiang F; Wang L; Ying H; Sun J; Zhao J; Lu Y; Bian Z; Chen J; Fang A; Zhang X; Larsson SC; Mantzoros CS; Wang W; Yuan S; Ding Y; Li X
Article: CLINICAL GASTROENTEROLOGY AND HEPATOLOGY. 2024;:S1542-3565(24)00980-7
Dietary Antioxidant Capacity, Genetic Susceptibility and Polymorphism, and Inflammatory Bowel Disease Risk in a Prospective Cohort.
Chen J; Dan L; Yuan S; Fu T; Sun J; Wolk A; Ludvigsson JF; Li X; Wang X; Larsson SC
Journal article: FERTILITY AND STERILITY. 2024;122(5):960-961
Reply of the authors: a commentary on: "Association of serum uric acid with women's ovarian reserve: observational study and Mendelian randomization analyses"
Wang G; Yang H; Jiang X; Mao W; Li P; Lin X; Li Y; Ye Z; Zhang Y; Chen W; Yuan S; Zhao Y; Mu L
Journal article: HUMAN REPRODUCTION. 2024;39(12):deae244
Mendelian randomization and multi-omics approach analyses reveal impaired glucose metabolism and oxidative phosphorylation in visceral adipose tissue of women with polycystic ovary syndrome
Zhang Y; Jiang X; Song X; Zhang J; Mao W; Chen W; Yuan S; Chen Y; Mu L; Zhao Y
Journal article: JVS - VASCULAR SCIENCE. 2024;:100258
Associations of Genetic and Lifestyle Risk Factors With Incident Peripheral Artery Disease: A Prospective Cohort Study
Yuan S; Sun Y; Chen J; Sharma P; Levin MG; Larsson S; Damrauer SM
Journal article: 2024
Systematic Investigation of Plasma Proteome to Discover Potential Interventional Targets and Prediction Biomarkers for Chronic Liver Diseases
Li X; Sun J; Zhou S; Zhao J; Jiang F; Li T; Zhang M; Li J; Yuan S; Li X; Ding Y
Article: DIABETOLOGIA. 2024;67(8):1630-1641
Coeliac disease and type 2 diabetes risk: a nationwide matched cohort and Mendelian randomisation study
Yuan S; Leffler D; Lebwohl B; Green PHR; Sun J; Carlsson S; Larsson SC; Ludvigsson JF
Article: JOURNAL OF THE NATIONAL CANCER INSTITUTE. 2024;116(8):1303-1312
Systematic investigation of genetically determined plasma and urinary metabolites to discover potential interventional targets for colorectal cancer
Sun J; Zhao J; Zhou S; Li X; Li T; Wang L; Yuan S; Chen D; Law PJ; Larsson SC; Farrington SM; Houlston RS; Dunlop MG; Theodoratou E; Li X
Article: FERTILITY AND STERILITY. 2024;122(1):162-173
Association of serum uric acid with women 's ovarian reserve: observational study and Mendelian randomization analyses
Wang G; Yang H; Jiang X; Mao W; Li P; Lin X; Li Y; Ye Z; Zhang Y; Chen W; Yuan S; Zhao Y; Mu L
Journal article: ISCIENCE. 2024;27(6):109931
Sleep, physical activity, and sedentary behaviors in relation to overall cancer and site-specific cancer risk: A prospective cohort study
Zhang R; Lu Y; Bian Z; Zhou S; Xu L; Jiang F; Yuan S; Tan X; Chen X; Ding Y; Li X
Article: EUROPEAN HEART JOURNAL - QUALITY OF CARE AND CLINICAL OUTCOMES. 2024;10(4):357-365
Risk of incident cardiovascular disease among patients with gastrointestinal disorder: a prospective cohort study of 330751 individuals
Chen J; Sun Y; Fu T; Lu S; Shi W; Zhao J; Li S; Li X; Yuan S; Larsson SC
Journal article: EGASTROENTEROLOGY. 2024;2(2):e100058
Mendelian randomisation analysis for intestinal disease: achievement and future
Ruan X; Che T; Chen X; Sun Y; Fu T; Yuan S; Li X; Chen J; Wang X
Article: CLINICAL NUTRITION. 2024;43(6):1386-1394
Ultra-processed foods and human health: An umbrella review and updated meta-analyses of observational evidence
Dai S; Wellens J; Yang N; Li D; Wang J; Wang L; Yuan S; He Y; Song P; Munger R; Kent MP; MacFarlane AJ; Mullie P; Duthie S; Little J; Theodoratou E; Li X
Article: STROKE. 2024;55(6):1582-1591
Risk Factors for Intracerebral Hemorrhage: Genome-Wide Association Study and Mendelian Randomization Analyses
Larsson SC; Chen J; Gill D; Burgess S; Yuan S
Article: RHEUMATOLOGY. 2024;:keae308
Modifiable risk factors and inflammation-related proteins in polymyalgia rheumatica: genome-wide meta-analysis and Mendelian randomization
Zhao SS; Mackie SL; Larsson SC; Burgess S; Yuan S
Article: INTERNATIONAL JOURNAL OF CANCER. 2024;154(10):1709-1718
Healthy lifestyle and cancer survival: A multinational cohort study
Bian Z; Zhang R; Yuan S; Fan R; Wang L; Larsson SC; Theodoratou E; Zhu Y; Wu S; Ding Y; Li X
Journal article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2024;44(Suppl_1):a3117
Abstract 3117: Cannabis Use Disorder And The Risk Of Atherosclerotic Cardiovascular Diseases
Sharma P; Paranjpe I; Judy R; Yuan S; Lee DJ; Nathanson KL; Levin MG; Damrauer SM
Article: EBIOMEDICINE. 2024;103:105110
Sedentary lifestyle, physical activity, and gastrointestinal diseases: evidence from mendelian randomization analysis
Chen J; Ruan X; Fu T; Lu S; Gill D; He Z; Burgess S; Giovannucci EL; Larsson SC; Deng M; Yuan S; Li X
Article: EBIOMEDICINE. 2024;103:105126
Impact of ambient air pollution on colorectal cancer risk and survival: insights from a prospective cohort and epigenetic Mendelian randomization study
Jiang F; Zhao J; Sun J; Chen W; Zhao Y; Zhou S; Yuan S; Timofeeva M; Law PJ; Larsson SC; Chen D; Houlston RS; Dunlop MG; Theodoratou E; Li X
Journal article: EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (EJPC). 2024;:zwae142
Association between alcohol consumption and peripheral artery disease: Two de novo prospective cohorts and a systematic review with meta-analysis.
Yuan S; Wu J; Chen J; Sun Y; Burgess S; Li X; Åkesson A; Larsson SC
Article: EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (EJPC). 2024;:zwae142
Association between alcohol consumption and peripheral artery disease: two de novo prospective cohorts and a systematic review with meta-analysis
Yuan S; Wu J; Chen J; Sun Y; Burgess S; Li X; Akesson A; Larsson SC
Article: EBIOMEDICINE. 2024;101:105033
Phenome-wide Mendelian randomization analysis reveals multiple health comorbidities of coeliac disease
Yuan S; Jiang F; Chen J; Lebwohl B; Green PHR; Leffer D; Larsson SC; Li X; Ludvigsson JF
Article: AMERICAN JOURNAL OF PREVENTIVE MEDICINE. 2024;66(3):516-525
Digestive System Diseases, Genetic Risk, and Incident Dementia: A Prospective Cohort Study
Yuan S; Dan L; Zhang Y; Wu J; Zhao J; Kivipelto M; Chen J; Ludvigsson JF; Li X; Larsson SC
Article: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2024;22(3):738-748
Proteomic insights into modifiable risk of venous thromboembolism and cardiovascular comorbidities
Yuan S; Xu F; Zhang H; Chen J; Ruan X; Li Y; Burgess S; Akesson A; Li X; Gill D; Larsson SC
Article: BMC MEDICINE. 2024;22(1):81
Genetic investigation into the broad health implications of caffeine: evidence from phenome-wide, proteome-wide and metabolome-wide Mendelian randomization
Zagkos L; Cronje HT; Woolf B; de La Harpe R; Burgess S; Mantzoros CS; Elliott P; Yuan S; Larsson SC; Tzoulaki I; Gill D
Article: AMERICAN JOURNAL OF HEMATOLOGY. 2024;99(2):172-181
Long-term risk of venous thromboembolism among patients with gastrointestinal non-neoplastic and neoplastic diseases: A prospective cohort study of 484?211 individuals
Yuan S; Sun Y; Chen J; Li X; Larsson SC
Article: JOURNAL OF AUTOIMMUNITY. 2024;143:103170
Older age of celiac disease diagnosis and risk of autoimmune disease: A nationwide matched case-control study
Yuan S; Leffler D; Lebwohl B; Green PHR; Larsson SC; Soderling J; Sun J; Ludvigsson JF
Journal article: JOURNAL OF CROHN'S AND COLITIS. 2024;18(Supplement_1):i2083-i2084
P1169 Multimorbidity and Disease Trajectories in Patients with INFLAMMATORY BOWEL DISEASES: Insights from Observational and Genetic Analyses
Jiang F; Zhao J; Chen J; Wang L; Yuan S; Kalla R; Wellens J; Nowak J; Larrson S; Ludvigsson J; Satsangi J; Theodoratou E; Li X
Article: EBIOMEDICINE. 2024;99:104934
Multi-omic insight into the molecular networks of mitochondrial dysfunction in the pathogenesis of inflammatory bowel disease
Chen J; Ruan X; Sun Y; Hu S; Yuan S; Li X
Article: BMC MEDICINE. 2023;21(1):485
Proteomic insights into the associations between obesity, lifestyle factors, and coronary artery disease
Yang F; Xu F; Zhang H; Gill D; Larsson SC; Li X; Cui H; Yuan S
Article: JOURNAL OF HUMAN GENETICS. 2023;68(12):805-812
Proteome-wide mendelian randomization identifies causal plasma proteins in venous thromboembolism development
Li H; Zhang Z; Qiu Y; Weng H; Yuan S; Zhang Y; Zhang Y; Xi L; Xu F; Ji X; Hao R; Yang P; Chen G; Zuo X; Zhai Z; Wang C
Article: CYTOTHERAPY. 2023;25(11):1155-1166
Single-cell transcriptome analysis reveals the effectiveness of cytokine priming irrespective of heterogeneity in mesenchymal stromal cells
Wan Z; Chen Y-F; Pan Q; Wang Y; Yuan S; Chin HY; Wu H-H; Lin W-T; Cheng P-Y; Yang Y-J; Wang Y-F; Kumta SM; Lee C-W; Lee OK-S
Article: INTERNATIONAL JOURNAL OF CANCER. 2023;153(9):1602-1611
Association between antibiotic use during early life and early-onset colorectal cancer risk overall and according to polygenic risk and FUT2 genotypes
Jiang F; Boakye D; Sun J; Wang L; Yu L; Zhou X; Zhao J; Bian Z; Song P; He Y; Zhu Y; Chen J; Yuan S; Song M; Larsson SC; Giovannucci EL; Theodoratou E; Ding K; Li X
Article: INTERNATIONAL JOURNAL OF CANCER. 2023;153(8):1477-1486
Exploring the cross-cancer effect of smoking and its fingerprints in blood DNA methylation on multiple cancers: A Mendelian randomization study
Zhou Y; Zhou X; Sun J; Wang L; Zhao J; Chen J; Yuan S; He Y; Timofeeva M; Spiliopoulou A; Mesa-Eguiagaray I; Farrington SM; Ding K; Dunlop MG; Qian X; Theodoratou E; Li X
Article: BRITISH JOURNAL OF CANCER. 2023;129(8):1306-1313
Dissecting the pathogenic effects of smoking and its hallmarks in blood DNA methylation on colorectal cancer risk
Zhou X; Xiao Q; Jiang F; Sun J; Wang L; Yu L; Zhou Y; Zhao J; Zhang H; Yuan S; Timofeeva M; Spiliopoulou A; Mesa-Eguiagaray I; Farrington SM; Law PJ; Houlston RS; Ding K; Dunlop MG; Theodoratou E; Li X
Article: OBESITY. 2023;31(10):2603-2614
Birth weight, childhood obesity, adulthood obesity and body composition, and gastrointestinal diseases: a Mendelian randomization study
Yuan S; Ruan X; Sun Y; Fu T; Zhao J; Deng M; Chen J; Li X; Larsson SC
Article: CELL REPORTS MEDICINE. 2023;4(9):101174
Plasma proteins and onset of type 2 diabetes and diabetic complications: Proteome-wide Mendelian randomization and colocalization analyses
Yuan S; Xu F; Li X; Chen J; Zheng J; Mantzoros CS; Larsson SC
Article: FOOD AND FUNCTION. 2023;14(18):8597-8603
A nutrient-wide association study for the risk of cardiovascular disease in the China Health and Nutrition Survey (CHNS) and the National Health and Nutrition Examination Survey (NHANES)
Zhang M-J; Zhang M-Z; Yuan S; Yang H-G; Lu G-L; Chen R; He Q-Q
Article: GENOME MEDICINE. 2023;15(1):75
Identification of novel protein biomarkers and drug targets for colorectal cancer by integrating human plasma proteome with genome
Sun J; Zhao J; Jiang F; Wang L; Xiao Q; Han F; Chen J; Yuan S; Wei J; Larsson SC; Zhang H; Dunlop MG; Farrington SM; Ding K; Theodoratou E; Li X
Article: JOURNAL OF NUTRITION. 2023;153(8):2291-2297
Higher Adherence to Cardioprotective Diet is Associated with Reduced Risk of Enterotomy and All-Cause Mortality among 5549 Individuals with Inflammatory Bowel Disease in a Prospective Cohort Study
Dan L; Yuan S; Ruan X; Sun Y; Fu T; Chen J; Li X
Article: EUROPEAN JOURNAL OF CLINICAL NUTRITION. 2023;77(8):811-814
Genetically predicted coffee and tea consumption and risk of intracranial aneurysm
Zhang Z; Wang M; Yuan S; Larsson SCC; Liu X
Article: CANCER EPIDEMIOLOGY, BIOMARKERS AND PREVENTION. 2023;32(8):1048-1060
Field Synopsis of Environmental and Genetic Risk Factors of Sporadic Early-Onset Colorectal Cancer and Advanced Adenoma
Zhang R; Boakye D; Yang N; Zhou X; Zhou Y; Jiang F; Yu L; Wang L; Sun J; Yuan S; Chen J; Hamilton AC; Coleman HG; Larsson SC; Little J; Dunlop MG; Giovannucci EL; Theodoratou E; Li X
Article: CLINICAL NUTRITION. 2023;42(8):1268-1275
Ultra-processed food intake and incident venous thromboembolism risk: Prospective cohort study
Yuan S; Chen J; Fu T; Li X; Bruzelius M; Akesson A; Larsson SC
Article: JOURNAL OF THE ENDOCRINE SOCIETY. 2023;7(8):bvad090
Physical Activity, Sedentary Behavior, and Type 2 Diabetes: Mendelian Randomization Analysis
Yuan S; Li X; Liu Q; Wang Z; Jiang X; Burgess S; Larsson SC
Journal article: BMJ ONCOLOGY. 2023;2(1):e000049
Global trends in incidence, death, burden and risk factors of early-onset cancer from 1990 to 2019
Zhao J; Xu L; Sun J; Song M; Wang L; Yuan S; Zhu Y; Wan Z; Larsson S; Tsilidis K; Dunlop M; Campbell H; Rudan I; Song P; Theodoratou E; Ding K; Li X
Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2023;131(7):77010
Ambient Air Pollution and Risk of Enterotomy, Gastrointestinal Cancer, and All-Cause Mortality among 4,708 Individuals with Inflammatory Bowel Disease: A Prospective Cohort Study
Chen J; Dan L; Sun Y; Yuan S; Liu W; Chen X; Jiang F; Fu T; Zhang H; Deng M; Wang X; Li X
Article: HUMAN MOLECULAR GENETICS. 2023;32(12):2093-2102
Cross-cancer pleiotropic analysis identifies three novel genetic risk loci for colorectal cancer
Sun J; Wang L; Zhou X; Hu L; Yuan S; Bian Z; Chen J; Zhu Y; Farrington SM; Campbell H; Ding K; Zhang D; Dunlop MG; Theodoratou E; Li X
Article: MOLECULAR NEUROBIOLOGY. 2023;60(6):3004-3009
Serum Calcium, 25-Hydroxyvitamin D, and Parathyroid Hormone Levels in Relation to Aneurysmal Subarachnoid Hemorrhage
Zhang Z; Yuan S; Larsson SC; Wang M; Liu X
Article: CANCER EPIDEMIOLOGY, BIOMARKERS AND PREVENTION. 2023;32(6):809-817
Exploring the Complex Relationship between Gut Microbiota and Risk of Colorectal Neoplasia Using Bidirectional Mendelian Randomization Analysis
Li W; Zhou X; Yuan S; Wang L; Yu L; Sun J; Chen J; Xiao Q; Wan Z; Zheng J-S; Zhang C-X; Larsson SC; Farrington SM; Law P; Houlston RS; Tomlinson I; Ding K-F; Dunlop MG; Theodoratou E; Li X
Article: TRANSLATIONAL PSYCHIATRY. 2023;13(1):146
Depression and 24 gastrointestinal diseases: a Mendelian randomization study
Ruan X; Chen J; Sun Y; Zhang Y; Zhao J; Wang X; Li X; Yuan S; Larsson SCC
Article: JOURNAL OF CROHN'S AND COLITIS. 2023;17(5):777-785
Bidirectional Mendelian Randomisation Analysis Provides Evidence for the Causal Involvement of Dysregulation of CXCL9, CCL11 and CASP8 in the Pathogenesis of Ulcerative Colitis
Chen J; Zhou Y; Sun Y; Yuan S; Kalla R; Sun J; Zhao J; Wang L; Chen X; Zhou X; Dai S; Zhang Y; Ho G-T; Xia D; Cao Q; Liu Z; Larsson SC; Wang X; Ding K; Halfvarson J; Li X; Theodoratou E; Satsangi J
Article: EUROPEAN HEART JOURNAL OPEN. 2023;3(3):oead056
Circulating proteins and peripheral artery disease risk: observational and Mendelian randomization analyses.
Yuan S; Titova OE; Zhang K; Chen J; Li X; Klarin D; Åkesson A; Damrauer SM; VA Million Veteran Program; Larsson SC
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2023;201(4):783-792
Plasma protein and venous thromboembolism: prospective cohort and mendelian randomisation analyses
Yuan S; Titova OE; Zhang K; Gou W; Schillemans T; Natarajan P; Chen J; Li X; Akesson A; Bruzelius M; Klarin D; Damrauer SM; Larsson SC
Article: JOURNAL OF CROHN'S AND COLITIS. 2023;17(4):535-552
Intake of Ultra-processed Foods Is Associated with an Increased Risk of Crohn's Disease: A Cross-sectional and Prospective Analysis of 187 154 Participants in the UK Biobank
Chen J; Wellens J; Kalla R; Fu T; Deng M; Zhang H; Yuan S; Wang X; Theodoratou E; Li X; Satsangi J
Article: DIABETES CARE. 2023;46(4):828-835
Gastrointestinal Consequences of Type 2 Diabetes Mellitus and Impaired Glycemic Homeostasis: A Mendelian Randomization Study
Chen J; Yuan S; Fu T; Ruan X; Qiao J; Wang X; Li X; Gill D; Burgess S; Giovannucci EL; Larsson SC
Article: EUROPEAN HEART JOURNAL OPEN. 2023;3(2):oead008
Sleep duration, daytime napping, and risk of peripheral artery disease: multinational cohort and Mendelian randomization studies.
Yuan S; Levin MG; Titova OE; Chen J; Sun Y; Million Veteran Program VA; Åkesson A; Li X; Damrauer SM; Larsson SC
Article: EBIOMEDICINE. 2023;89:104494
Therapeutic targets for inflammatory bowel disease: proteome-wide Mendelian randomization and colocalization analyses
Chen J; Xu F; Ruan X; Sun J; Zhang Y; Zhang H; Zhao J; Zheng J; Larsson SC; Wang X; Li X; Yuan S
Article: EBIOMEDICINE. 2023;89:104488
Mendelian randomization and clinical trial evidence supports TYK2 inhibition as a therapeutic target for autoimmune diseases
Yuan S; Wang L; Zhang H; Xu F; Zhou X; Yu L; Sun J; Chen J; Ying H; Xu X; Yu Y; Spiliopoulou A; Shen X; Wilson J; Gill D; Theodoratou E; Larsson SC; Li X
Article: ALIMENTARY PHARMACOLOGY AND THERAPEUTICS. 2023;57(5):475-485
Sleep duration and daytime napping in relation to incident inflammatory bowel disease: a prospective cohort study
Yuan S; Sun Y; Tan X; Geng J; Sun J; Chen X; Yu L; Wang J; Zhou X; Hesketh T; Larsson SC; Chen J; Wang X; Li X; Liu Z
Article: AMERICAN JOURNAL OF GASTROENTEROLOGY. 2023;118(3):511-522
The Contribution of Genetic Risk and Lifestyle Factors in the Development of Adult-Onset Inflammatory Bowel Disease: A Prospective Cohort Study
Sun Y; Yuan S; Chen X; Sun J; Kalla R; Yu L; Wang L; Zhou X; Kong X; Hesketh T; Ho G-T; Ding K; Dunlop M; Larsson SC; Satsangi J; Chen J; Wang X; Li X; Theodoratou E; Giovannucci EL
Article: INTERNATIONAL JOURNAL OF CANCER. 2023;152(4):697-704
Morning chronotype and digestive tract cancers: Mendelian randomization study
Yuan S; Mason AM; Titova OE; Vithayathil M; Kar S; Chen J; Li X; Burgess S; Larsson SC
Article: ELIFE. 2023;12:e84051
Smoking, alcohol consumption, and 24 gastrointestinal diseases: Mendelian randomization analysis
Yuan S; Chen J; Ruan X; Sun Y; Zhang K; Wang X; Li X; Gill D; Burgess S; Giovannucci E; Larsson SC
Article: CLINICAL GASTROENTEROLOGY AND HEPATOLOGY. 2023;21(2):398-405.e4
Inverse Association Between Serum 25-Hydroxyvitamin D and Nonalcoholic Fatty Liver Disease
Yuan S; Larsson SC
Article: ALIMENTARY PHARMACOLOGY AND THERAPEUTICS. 2023;57(4):399-408
Antioxidants, minerals and vitamins in relation to Crohn's disease and ulcerative colitis: A Mendelian randomization study
Chen J; Ruan X; Yuan S; Deng M; Zhang H; Sun J; Yu L; Satsangi J; Larsson SC; Therdoratou E; Wang X; Li X
Article: NUTRITION. 2023;106:111910
Plasma phospholipid arachidonic acid in relation to non-alcoholic fatty liver disease: Mendelian randomization study
Chen J; Ruan X; Sun Y; Li X; Yuan S; Larsson SC
Journal article: FRONTIERS IN IMMUNOLOGY. 2023;14:1240754
Therapeutic role of interleukin-1 receptor antagonist in pancreatic diseases: mendelian randomization study.
Yuan S; Miao Y; Ruan X; Chen J; Li X; Larsson SC
Article: FRONTIERS IN MEDICINE. 2023;10:1180596
Atopic dermatitis and chronic kidney disease: a bidirectional Mendelian randomization study
Zhang H; Yuan S; Li Y; Li D; Yu Z; Hu L; Li X; Wang Y; Larsson SC
Article: FRONTIERS IN ENDOCRINOLOGY. 2023;14:1278273
Apolipoprotein B and interleukin 1 receptor antagonist: reversing the risk of coronary heart disease
Yang F; Huangfu N; Shen J; Su P; Zhu L; Cui H; Yuan S
Journal article: FOOD AND FUNCTION. 2023;14(18):8597-8603
A nutrient-wide association study for the risk of cardiovascular disease in the China Health and Nutrition Survey (CHNS) and the National Health and Nutrition Examination Survey (NHANES)
Zhang M-J; Zhang M-Z; Yuan S; Yang H-G; Lu G-L; Chen R; He Q-Q
Article: FRONTIERS IN IMMUNOLOGY. 2023;14:1240754
Therapeutic role of interleukin-1 receptor antagonist in pancreatic diseases: mendelian randomization study
Yuan S; Miao Y; Ruan X; Chen J; Li X; Larsson SC
Article: AMERICAN JOURNAL OF CLINICAL NUTRITION. 2022;116(6):1595-1609
Homocysteine, folate, and nonalcoholic fatty liver disease: a systematic review with meta-analysis and Mendelian randomization investigation
Yuan S; Chen J; Dan L; Xie Y; Sun Y; Li X; Larsson SC
Article: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 2022;51(6):1931-1942
Genetically predicted sex hormone levels and health outcomes: phenome-wide Mendelian randomization investigation
Yuan S; Wang L; Sun J; Yu L; Zhou X; Yang J; Zhu Y; Gill D; Burgess S; Denny JC; Larsson SC; Theodoratou E; Li X
Article: ARTHRITIS RESEARCH & THERAPY. 2022;24(1):270
Rheumatoid arthritis and risk of site-specific cancers: Mendelian randomization study in European and East Asian populations
Yuan S; Chen J; Ruan X; Vithayathil M; Kar S; Li X; Mason AM; Burgess S; Larsson SC
Article: JOURNAL OF SLEEP RESEARCH. 2022;31(6):e13681
Self-reported symptoms of sleep-disordered breathing and risk of cardiovascular diseases: Observational and Mendelian randomization findings
Titova OE; Yuan S; Baron JA; Lindberg E; Michaelsson K; Larsson SC
Article: BMC MEDICINE. 2022;20(1):455
Health effects of milk consumption: phenome-wide Mendelian randomization study
Yuan S; Sun J; Lu Y; Xu F; Li D; Jiang F; Wan Z; Li X; Qin L-Q; Larsson SC
Journal article: CIRCULATION. 2022;146(Suppl_1):a11460
Abstract 11460: Sleep Duration, Quality, and Risk of Peripheral Artery Disease: Multinational Cohort and Mendelian Randomization Studies
Yuan S; Levin MG; Titova O; Chen J; Sun Y; Akesson A; Li X; Damrauer SM; Larsson S
Article: GENES. 2022;13(11):2010
Bidirectional Association between Major Depressive Disorder and Gastroesophageal Reflux Disease: Mendelian Randomization Study
Miao Y; Yuan S; Li Y; Chen J; Li X; Larsson SC; Zhang Q
Article: SCIENTIFIC REPORTS. 2022;12(1):17703
A Mendelian randomization study of genetic predisposition to autoimmune diseases and COVID-19
Li S; Yuan S; Schooling CM; Larsson SC
Article: ELIFE. 2022;11:e79720
Genetically predicted high IGF-1 levels showed protective effects on COVID-19 susceptibility and hospitalization: a Mendelian randomisation study with data from 60 studies across 25 countries
Li X; Zhou Y; Yuan S; Zhou X; Wang L; Sun J; Yu L; Zhu J; Zhang H; Yang N; Dai S; Song P; Larsson SC; Theodoratou E; Zhu Y; Li X; Giamarellos-Bourboulis EJ
Article: CLINICAL NUTRITION. 2022;41(10):2113-2123
Coffee consumption and cancer risk: a Mendelian randomisation study
Carter P; Yuan S; Kar S; Vithayathil M; Mason AM; Burgess S; Larsson SC
Article: ARTHRITIS & RHEUMATOLOGY. 2022;74(10):1638-1647
Genetic Liability to Rheumatoid Arthritis in Relation to Coronary Artery Disease and Stroke Risk
Yuan S; Carter P; Mason AM; Yang F; Burgess S; Larsson SC
Article: DIABETES. 2022;71(10):2222-2232
Differentiating Associations of Glycemic Traits With Atherosclerotic and Thrombotic Outcomes: Mendelian Randomization Investigation
Yuan S; Mason AM; Burgess S; Larsson SC
Article: NUTRIENTS. 2022;14(16):3354
Plasma Phospholipid Fatty Acids and Risk of Venous Thromboembolism: Mendelian Randomization Investigation
Yuan S; Li X; Morange P-E; Bruzelius M; Larsson SC
Article: SCIENTIFIC REPORTS. 2022;12(1):12139
Swedish snuff (snus) dipping, cigarette smoking, and risk of peripheral artery disease: a prospective cohort study
Yuan S; Titova OE; Damrauer SM; Akesson A; Larsson SC
Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY (EJE). 2022;37(7):723-733
Lifestyle and metabolic factors for nonalcoholic fatty liver disease: Mendelian randomization study
Yuan S; Chen J; Li X; Fan R; Arsenault B; Gill D; Giovannucci EL; Zheng J-S; Larsson SC
Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY (EJE). 2022;37(7):747-754
Adiposity, diabetes, lifestyle factors and risk of gastroesophageal reflux disease: a Mendelian randomization study
Yuan S; Larsson SC
Article: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2022;64(1):83-91
A Prospective Evaluation of Modifiable Lifestyle Factors in Relation to Peripheral Artery Disease Risk
Yuan S; Damrauer SM; Hakansson N; Akesson A; Larsson SC
Article: INTERNATIONAL JOURNAL OF CANCER. 2022;151(1):83-94
Alcohol consumption, DNA methylation and colorectal cancer risk: Results from pooled cohort studies and Mendelian randomization analysis
Zhou X; Wang L; Xiao J; Sun J; Yu L; Zhang H; Meng X; Yuan S; Timofeeva M; Law PJ; Houlston RS; Ding K; Dunlop MG; Theodoratou E; Li X
Article: CLINICAL NUTRITION. 2022;41(6):1191-1196
Anti-inflammatory diet and incident peripheral artery disease: Two prospective cohort studies
Yuan S; Bruzelius M; Damrauer SM; Hakansson N; Wolk A; Akesson A; Larsson SC
Article: CLINICAL GASTROENTEROLOGY AND HEPATOLOGY. 2022;20(5):1077-1084
Genetically Predicted Adiposity, Diabetes, and Lifestyle Factors in Relation to Diverticular Disease
Yuan S; Larsson SC
Article: JOURNAL OF NEUROLOGY. 2022;269(5):2460-2468
Sleep-disordered breathing-related symptoms and risk of stroke: cohort study and Mendelian randomization analysis
Titova OE; Yuan S; Baron JA; Lindberg E; Michaelsson K; Larsson SC
Article: BMC MEDICINE. 2022;20(1):106
The impact and causal directions for the associations between diagnosis of ADHD, socioeconomic status, and intelligence by use of a bi-directional two-sample Mendelian randomization design
Michaelsson M; Yuan S; Melhus H; Baron JA; Byberg L; Larsson SC; Michaelsson K
Article: INTERNATIONAL JOURNAL OF CANCER. 2022;150(7):1134-1140
Selenium and cancer risk: Wide-angled Mendelian randomization analysis
Yuan S; Mason AM; Carter P; Vithayathil M; Kar S; Burgess S; Larsson SC
Article: SEMINARS IN ARTHRITIS AND RHEUMATISM. 2022;53:151958
Interleukins and rheumatoid arthritis: bi-directional Mendelian randomization investigation
Yuan S; Li X; Lin A; Larsson SC
Journal article: PSYCHOLOGY, HEALTH AND MEDICINE. 2022;27(3):528-536
Associations of health-risk behaviors with mental health among Chinese children
Zhang J; Liu M-W; Yu H-J; Chen Q-T; Tang B-W; Yuan S; He Q-Q
Article: NUTRIENTS. 2022;14(6):1153
Alcohol, Coffee, and Milk Intake in Relation to Epilepsy Risk
Zhang Z; Wang M; Yuan S; Liu X
Article: CLINICAL GASTROENTEROLOGY AND HEPATOLOGY. 2022;20(3):e529-e537
Obesity, Type 2 Diabetes, Lifestyle Factors, and Risk of Gallstone Disease: A Mendelian Randomization Investigation
Yuan S; Gill D; Giovannucci EL; Larsson SC
Article: EBIOMEDICINE. 2022;76:103865
Health effects of high serum calcium levels: Updated phenome-wide Mendelian randomisation investigation and review of Mendelian randomisation studies
Yuan S; Yu L; Gou W; Wang L; Sun J; Li D; Lu Y; Cai X; Yu H; Yuan C; Zheng J-S; Larsson SC; Theodoratou E; Li X
Article: PAIN. 2022;163(2):e342-e348
Alcohol, coffee consumption, and smoking in relation to migraine: a bidirectional Mendelian randomization study
Yuan S; Daghlas I; Larsson SC
Article: EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (EJPC). 2022;28(16):1829-1837
Genetically predicted circulating vitamin C in relation to cardiovascular disease
Yuan S; Zheng J-S; Mason AM; Burgess S; Larsson SC
Article: SCIENTIFIC REPORTS. 2022;12(1):409
Metabolic and lifestyle factors in relation to senile cataract: a Mendelian randomization study
Yuan S; Wolk A; Larsson SC
Article: BMJ MEDICINE. 2022;1(1):e000277
Effects of metabolic traits, lifestyle factors, and pharmacological interventions on liver fat: mendelian randomisation study
Yuan S; Chen J; Vujkovic M; Chang K-M; Li X; Larsson SC; Gill D
Article: FRONTIERS IN GENETICS. 2022;13:814457
GDF-15 as a Therapeutic Target of Diabetic Complications Increases the Risk of Gallstone Disease: Mendelian Randomization and Polygenic Risk Score Analysis
Yu L; Zhou Y; Wang L; Zhou X; Sun J; Xiao J; Xu X; Larsson SC; Yuan S; Li X
Article: AMERICAN JOURNAL OF KIDNEY DISEASES. 2022;79(1):9-14.e1
Coffee and Caffeine Consumption and Risk of Kidney Stones: A Mendelian Randomization Study
Yuan S; Larsson SC
Article: JOURNAL OF THROMBOSIS AND THROMBOLYSIS. 2022;53(1):43-50
Causal effect of renal function on venous thromboembolism: a two-sample Mendelian randomization investigation
Yuan S; Bruzelius M; Larsson SC
Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2021;10(21):e022286
Cardiometabolic, Lifestyle, and Nutritional Factors in Relation to Varicose Veins: A Mendelian Randomization Study
Yuan S; Bruzelius M; Damrauer SM; Larsson SC
Article: NUTRITION. 2021;91-92:111310
Association of food expenditure with life expectancy in the United States, 2001-2014
Li Q-X; Yuan S; Yu Z; Larsson SC; He Q-Q
Article: CLINICAL ENDOCRINOLOGY. 2021;95(5):800-805
Genetically predicted insulin-like growth factor-I in relation to muscle mass and strength
Yuan S; Larsson SC
Article: NPJ GENOMIC MEDICINE. 2021;6(1):86
Serum calcium and 25-hydroxyvitamin D in relation to longevity, cardiovascular disease and cancer: a Mendelian randomization study
Yuan S; Baron JA; Michaelsson K; Larsson SC
Article: JOURNAL OF ALZHEIMER'S DISEASE. 2021;83(4):1815-1823
Genetically Predicted Coffee Consumption and Risk of Alzheimer's Disease and Stroke
Zhang Z; Wang M; Yuan S; Cai H; Zhu S-G; Liu X
Article: FERTILITY AND STERILITY. 2021;116(4):1061-1067
Smoking, alcohol and coffee consumption and pregnancy loss: a Mendelian randomization investigation
Yuan S; Liu J; Larsson SC
Article: NUTRITION, METABOLISM AND CARDIOVASCULAR DISEASES. 2021;31(10):2831-2838
Anti-inflammatory diet and venous thromboembolism: Two prospective cohort studies
Yuan S; Bruzelius M; Damrauer SM; Hakansson N; Wolk A; Akesson A; Larsson SC
Article: MOLECULAR GENETICS AND METABOLISM. 2021;134(1-2):212-215
Assessing causal associations of obesity and diabetes with kidney stones using Mendelian randomization analysis
Yuan S; Larsson SC
Article: NUTRIENTS. 2021;13(8):2893
Genetically Predicted Milk Intake and Risk of Neurodegenerative Diseases
Zhang Z; Wang M; Yuan S; Larsson SC; Liu X
Article: NUTRIENTS. 2021;13(7):2218
Coffee Consumption and Cardiovascular Diseases: A Mendelian Randomization Study
Yuan S; Carter P; Mason AM; Burgess S; Larsson SC
Article: BRITISH JOURNAL OF CANCER. 2021;124(12):1997-2003
Genetically predicted circulating B vitamins in relation to digestive system cancers
Yuan S; Carter P; Vithayathil M; Kar S; Mason AM; Burgess S; Larsson SC
Article: CLINICAL NUTRITION. 2021;40(6):4180-4186
Egg, cholesterol and protein intake and incident type 2 diabetes mellitus: Results of repeated measurements from a prospective cohort study
Shuai Y; Liu M-W; He Q-Q; Larsson SC
Article: THROMBOSIS RESEARCH. 2021;202:119-124
Lifestyle factors and venous thromboembolism in two cohort studies
Yuan S; Bruzelius M; Hakansson N; Akesson A; Larsson SC
Article: BRAIN AND BEHAVIOR. 2021;11(5):e02098
Modifiable risk factors for epilepsy: A two-sample Mendelian randomization study
Yuan S; Tomson T; Larsson SC
Article: BMJ OPEN. 2021;11(4):e042762
Urban-rural disparity in cancer incidence in China, 2008-2012: a cross-sectional analysis of data from 36 cancer registers
Yuan S; Xie S-H
Article: BMC MEDICINE. 2021;19(1):97
Homocysteine, B vitamins, and cardiovascular disease: a Mendelian randomization study
Yuan S; Mason AM; Carter P; Burgess S; Larsson SC
Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2021;10(8):e019644
Genetically Proxied Inhibition of Coagulation Factors and Risk of Cardiovascular Disease: A Mendelian Randomization Study
Yuan S; Burgess S; Laffan M; Mason AM; Dichgans M; Gill D; Larsson SC
Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY (EJE). 2021;36(4):393-400
Genetic liability to insomnia in relation to cardiovascular diseases: a Mendelian randomisation study
Yuan S; Mason AM; Burgess S; Larsson SC
Article: NPJ GENOMIC MEDICINE. 2021;6(1):27
Gallstone disease, diabetes, calcium, triglycerides, smoking and alcohol consumption and pancreatitis risk: Mendelian randomization study
Yuan S; Giovannucci EL; Larsson SC
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2021;106(4):e1552-e1558
Insulin-like Growth Factor-1, Bone Mineral Density, and Fracture: A Mendelian Randomization Study
Yuan S; Wan Z-H; Cheng S-L; Michaelsson K; Larsson SC
Journal article: MEDICINE (UNITED KINGDOM). 2021;100(10):e24600
Associations of sleep duration and fruit and vegetable intake with the risk of metabolic syndrome in Chinese adults
Wang M-H; Shi T; Li Q; Chen H-M; Liu M-W; Lu Y-A; He Q; Chen R
Article: SCIENTIFIC REPORTS. 2021;11(1):4296
Genetically predicted education attainment in relation to somatic and mental health
Yuan S; Xiong Y; Michaelsson M; Michaelsson K; Larsson SC
Article: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2021;19(2):460-469
Overall and abdominal obesity in relation to venous thromboembolism
Yuan S; Bruzelius M; Xiong Y; Hakansson N; Akesson A; Larsson SC
Article: JOURNAL OF NEUROLOGY. 2021;268(1):114-124
An atlas on risk factors for multiple sclerosis: a Mendelian randomization study
Yuan S; Xiong Y; Larsson SC
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2021;51(1):78-86
Null association between serum 25-hydroxyvitamin D levels with allergic rhinitis, allergic sensitization and non-allergic rhinitis: A Mendelian randomization study
Feng Q; Bonnelykke K; Ek WE; Chawes BL; Yuan S; Cheung CL; Li GHY; Leung RYH; Cheung BMY
Article: ANNALS OF NEUROLOGY. 2020;88(6):1229-1236
Circulating Lipoprotein Lipids, Apolipoproteins and Ischemic Stroke
Yuan S; Tang B; Zheng J; Larsson SC
Article: DIABETOLOGIA. 2020;63(11):2359-2371
An atlas on risk factors for type 2 diabetes: a wide-angled Mendelian randomisation study
Yuan S; Larsson SC
Article: SCIENTIFIC REPORTS. 2020;10(1):17475
Causal associations between urinary sodium with body mass, shape and composition: a Mendelian randomization study
Feng Q; Yuan S; Yang Q; Lu Y; Loos RJF; Li GHY; Fei Y; Tsoi MF; Cheung CL; Cheung BMY
Article: CLINICAL NUTRITION. 2020;39(10):3119-3124
Causal associations of iron status with gout and rheumatoid arthritis, but not with inflammatory bowel disease
Yuan S; Larsson S
Article: INTERNATIONAL JOURNAL OF CANCER. 2020;147(7):1895-1903
Causal associations of thyroid function and dysfunction with overall, breast and thyroid cancer: A two-sample Mendelian randomization study
Yuan S; Kar S; Vithayathil M; Carter P; Mason AM; Burgess S; Larsson SC
Article: EUROPEAN JOURNAL OF NEUROLOGY. 2020;27(10):1913-1917
Interleukin-1 receptor antagonist, interleukin-2 receptor alpha subunit and amyotrophic lateral sclerosis
Yuan S; Roos PM; Larsson SC
Article: EBIOMEDICINE. 2020;59:102956
Effects of tumour necrosis factor on cardiovascular disease and cancer: A two-sample Mendelian randomization study
Yuan S; Carter P; Bruzelius M; Vithayathil M; Kar S; Mason AM; Lin A; Burgess S; Larsson SC
Journal article: JOURNAL OF AMERICAN COLLEGE HEALTH. 2020;68(6):587-592
The impact of a health education intervention on health behaviors and mental health among Chinese college students
Yang X-H; Yu H-J; Liu M-W; Zhang J; Tang B-W; Yuan S; Gasevic D; Paul K; Wang P-G; He Q-Q
Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2020;313:99-104
Circulating interleukins in relation to coronary artery disease, atrial fibrillation and ischemic stroke and its subtypes: A two-sample Mendelian randomization study
Yuan S; Lin A; He Q-Q; Burgess S; Larsson SC
Article: SCIENTIFIC REPORTS. 2020;10(1):13807
Associations of cigarette smoking with psychiatric disorders: evidence from a two-sample Mendelian randomization study
Yuan S; Yao H; Larsson SC
Journal article: INTERNATIONAL JOURNAL OF BEHAVIORAL MEDICINE. 2020;27(4):400-405
Association of Adverse Childhood Experiences with Health Risk Behaviors Among College Students in Zambia.
Zhang J; Tang B-W; Liu M-W; Yuan S; Yu H-J; Zhang R; Huang X-C; Nzala SH; Chikoya M; Wang P-G; He Q-Q
Article: DIABETOLOGIA. 2020;63(7):1305-1311
Major depressive disorder and cardiometabolic diseases: a bidirectional Mendelian randomisation study
Tang B; Yuan S; Xiong Y; He Q; Larsson SC
Article: DIABETES. 2020;69(7):1588-1596
Is Type 2 Diabetes Causally Associated With Cancer Risk? Evidence From a Two-Sample Mendelian Randomization Study
Yuan S; Kar S; Carter P; Vithayathil M; Mason AM; Burgess S; Larsson SC
Article: CLINICAL NUTRITION. 2020;39(7):2180-2186
Plasma phospholipid fatty acids, bone mineral density and fracture risk: Evidence from a Mendelian randomization study
Yuan S; Lemming EW; Michaelsson K; Larsson SC
Article: NUTRIENTS. 2020;12(2):E526-526
Iron Status and Cancer Risk in UK Biobank: A Two-Sample Mendelian Randomization Study
Yuan S; Carter P; Vithayathil M; Kar S; Giovannucci E; Mason AM; Burgess S; Larsson SC
Article: AMERICAN JOURNAL OF PREVENTIVE MEDICINE. 2020;58(2):294-301
Fat Intake and Hypertension Among Adults in China: The Modifying Effects of Fruit and Vegetable Intake
Yuan S; Yu H-J; Liu M-W; Tang B-W; Zhang J; Gasevic D; Larsson SC; He Q-Q
Article: NUTRIENTS. 2020;12(1):E194-194
Improving the Metabolic and Mental Health of Children with Obesity: A School-Based Nutrition Education and Physical Activity Intervention in Wuhan, China
Yu H-J; Li F; Hu Y-F; Li C-F; Yuan S; Song Y; Zheng M; Gong J; He Q-Q
Article: DIABETOLOGIA. 2020;63(1):116-123
Association of genetic variants related to plasma fatty acids with type 2 diabetes mellitus and glycaemic traits: a Mendelian randomisation study
Yuan S; Larsson SC
Article: SCIENTIFIC REPORTS. 2019;9(1):19342
A causal relationship between cigarette smoking and type 2 diabetes mellitus: A Mendelian randomization study
Yuan S; Larsson SC
Article: NUTRIENTS. 2019;11(12):E3001-3001
Plasma Phospholipid Fatty Acids, FADS1 and Risk of 15 Cardiovascular Diseases: A Mendelian Randomisation Study
Yuan S; Back M; Bruzelius M; Mason AM; Burgess S; Larsson S
Article: DIABETES CARE. 2019;42(12):2197-2203
Genetic Prediction of Serum 25-Hydroxyvitamin D, Calcium, and Parathyroid Hormone Levels in Relation to Development of Type 2 Diabetes: A Mendelian Randomization Study
Yuan S; Jiang X; Michaelsson K; Larsson SC
Article: CALCIFIED TISSUE INTERNATIONAL. 2019;105(6):582-588
Associations of Smoking and Alcohol and Coffee Intake with Fracture and Bone Mineral Density: A Mendelian Randomization Study
Yuan S; Michaelsson K; Wan Z; Larsson SC
Article: NUTRITION, METABOLISM AND CARDIOVASCULAR DISEASES. 2019;29(11):1185-1188
No association between coffee consumption and risk of atrial fibrillation: A Mendelian randomization study
Yuan S; Larsson SC
Journal article: ARCHIVES OF SEXUAL BEHAVIOR. 2019;48(7):2117-2123
Risky Sexual Behaviors and Associated Factors Among College Students in Lusaka, Zambia
Yang X-H; Yuan S; Zhang R; Yu J-F; Nzala SH; Wang P-G; He Q-Q
Article: NUTRIENTS. 2019;11(7):E1651-1651
Plasma Phospholipid Fatty Acids and Risk of Atrial Fibrillation: A Mendelian Randomization Study
Yuan S; Larsson SC
Journal article: JOURNAL OF AFFECTIVE DISORDERS. 2019;252:278-293
How does childhood maltreatment influence ensuing cognitive functioning among people with the exposure of childhood maltreatment? A systematic review of prospective cohort studies
Su Y; D'Arcy C; Yuan S; Meng X
Journal article: JOURNAL OF PUBLIC HEALTH. 2019;41(2):E169-E176
Cigarette smoking as a risk factor for type 2 diabetes in women compared with men: a systematic review and meta-analysis of prospective cohort studies
Yuan S; Xue H-L; Yu H-J; Huang Y; Tang B-W; Yang X-H; Li Q-X; He Q-Q
Journal article: EUROPEAN JOURNAL OF NUTRITION. 2018;57(7):2639-2647
Association between fruit and vegetable intake and the risk of hypertension among Chinese adults: a longitudinal study
Liu M-W; Yu H-J; Yuan S; Song Y; Tang B-W; Cao Z-K; Yang X-H; Towne SDJ; He Q-Q
Journal article: JOURNAL OF PEDIATRICS. 2018;200:150-154.e1
Cardiorespiratory Fitness Attenuates the Obesity Risk in Chinese Children Who Have Parents with Overweight/Obesity
Yu H-J; Cai L-B; Yang X-H; Yuan S; Li Q-X; He Q-Q
Journal article: BMC PUBLIC HEALTH. 2018;18(1):986
Associations of physical activity and fruit and vegetable intake with well-being and depressive symptoms among obese schoolchildren in Wuhan, China: a cross-sectional study
Yu H-J; Li F; Hu Y-F; Li C-F; Yang X-H; Yuan S; Huang Y; Tang B-W; Gong J; He Q-Q
Journal article: PUBLIC HEALTH. 2018;157:121-126
The association of fruit and vegetable consumption with changes in weight and body mass index in Chinese adults: a cohort study
Yuan S; Yu HJ; Liu MW; Huang Y; Yang XH; Tang BW; Song Y; Cao ZK; Wu HJ; He QQ; Gasevic D
Journal article: PUBLIC HEALTH. 2017;149:65-70
Association between obesity phenotypes and incident hypertension among Chinese adults: a prospective cohort study
Cao ZK; Huang Y; Yu HJ; Yuan S; Tang BW; Li QX; Li XT; Yang XH; He QQ
Journal article: MOLECULAR NUTRITION AND FOOD RESEARCH. 2017;61(6)
Dietary total flavonoids intake and risk of mortality from all causes and cardiovascular disease in the general population: A systematic review and meta-analysis of cohort studies
Liu X-M; Liu Y-J; Huang Y; Yu H-J; Yuan S; Tang B-W; Wang P-G; He Q-Q
Journal article: JOURNAL OF CHILD AND FAMILY STUDIES. 2017;26(5):1380-1387
Association between Child Abuse and Health Risk Behaviors among Chinese College Students
Chen Y-L; Liu X; Huang Y; Yu H-J; Yuan S; Ye Y-L; Li Q-X; He Q-Q
Journal article: PLOS ONE. 2017;12(11):e0188533
Combined effects of fruit and vegetables intake and physical activity on the risk of metabolic syndrome among Chinese adults
Li X-T; Liao W; Yu H-J; Liu M-W; Yuan S; Tang B-W; Yang X-H; Song Y; Huang Y; Cheng S-L; Chen Z-Y; Towne SDJ; Mao Z-F; He Q-Q
Journal article: MATERNAL AND CHILD HEALTH JOURNAL. 2016;20(9):1904-1910
Combined Association of Diet and Cardiorespiratory Fitness with Metabolic Syndrome in Chinese Schoolchildren
Liao W; Xiao D-M; Huang Y; Yu H-J; Yuan S; Chen T; Phongsavan P; Mao Z-F; He Q-Q
Journal article: PSYCHOLOGY, HEALTH AND MEDICINE. 2016;21(3):377-385
Associations between multiple health risk behaviors and mental health among Chinese college students
Ye Y-L; Wang P-G; Qu G-C; Yuan S; Phongsavan P; He Q-Q
Journal article: PREVENTING CHRONIC DISEASE. 2015;12:E01
Parental Weight Status and Offspring Cardiovascular Disease Risks: a Cross-Sectional Study of Chinese Children
McCarthy K; Ye Y-L; Yuan S; He Q-Q
Journal article:
Mendelian Randomization Analysis Revealed Pan-Effect of Smoking Instead of Alcohol Consumption on 24 Gastrointestinal Diseases
Yuan S; Chen J; Ruan X; Sun Y; Zhang K; Wang X; Li X; Gill D; Burgess S; Giovannucci E; Larsson S
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All other publications

Letter: GUT. 2024;74(1):e6
Concerns about instrumental variable selection for biological effect versus uptake of proton pump inhibitors in Mendelian randomisation analysis
Yuan S; Larsson SC; Gill D; Burgess S
Letter: FERTILITY AND STERILITY. 2024;122(6):1166
Reply of the authors: no association between celiac disease and female infertility: evidence from Mendelian randomization analysis
Yuan S; Ludvigsson JF
Preprint: MEDRXIV. 2024
Proteome-wide and mendelian randomisation analyses of chronic widespread pain: diagnosis, prognosis, and drug target discovery
Chen L; Kelleher E; Meng R; Liu D; Guo Y; Wang Y; Gao Y; Huang Z; Liang Z; Yuan S; Zeng C; Lei G; Ma J; Dong Y; Irani A; Xie J; Prieto-Alhambra D
Preprint: MEDRXIV. 2024;MEDRXIV
Plasma proteomics reveals the potential causal impact of extracellular matrix proteins on abdominal aortic aneurysm.
Khodursky S; Yuan S; Spin JM; Tsao PS; Levin MG; Damrauer SM
Preprint: MEDRXIV. 2024;MEDRXIV
Lipoprotein (a) is associated with increased risk of Abdominal Aortic Aneurysm.
Sharma P; Judy R; Yuan S; Gellatly C; Saxby KL; Bown MJ; Levin MG; Damrauer SM
Review: ENDOCRINE REVIEWS. 2024;45(4):437-459
Genetic and Epigenetic Landscape for Drug Development in Polycystic Ovary Syndrome
Chen Y; Wang G; Chen J; Wang C; Dong X; Chang H-M; Yuan S; Zhao Y; Mu L
Preprint: MEDRXIV. 2024
Modifiable risk factors and inflammation-related proteins in polymyalgia rheumatica: genome-wide meta-analysis and Mendelian randomisation
Zhao SS; Mackie S; Larsson S; Burgess S; Yuan S
Letter: GUT. 2024;73(5):878-879
Defining gene-lifestyle interactions in inflammatory bowel disease: progress towards understanding disease pathogenesis
Zhao J; Chen J; Sun Y; Yuan S; Wellens J; Kalla R; Theodoratou E; Li X; Satsangi J
Preprint: RESEARCH SQUARE. 2024
Novel genetic loci, lifestyle factors, and inflammatory markers identified as risk factors for sarcoidosis
Yuan S; Chen J; Zhao SS; Yarmolinsky J; Arkema E; Tsilidis K; Burgess S; Larsson S
Thesis / dissertation: 2024
Modifiable risk factors, blood proteins, and venous thromboembolism
Yuan, Shuai
Preprint: RESEARCH SQUARE. 2023
Dose Stasis Impact Venous Thrombosis via Hypercoagulability? Evidence from Multivariable Mendelian Randomization Analysis
Yuan S; Wiggins KL; Xiong Y; Smith NL; Damrauer SM; Larsson SC
Preprint: MEDRXIV. 2023;MEDRXIV
Deciphering the genetic architecture of atrial fibrillation offers insights into disease prediction, pathophysiology and downstream sequelae.
Yuan S; Li Y; Wang L; Xu F; Chen J; Levin MG; Xiong Y; Voight BF; Damrauer SM; Gill D; Burgess S; Åkesson A; Michaëlsson K; Li X; Shen X; Larsson SC
Letter: METABOLISM: CLINICAL AND EXPERIMENTAL. 2023;144:155560
Clarity and quality assessment of epidemiology of sarcopenia: Prevalence, risk factors, and consequences Response
Yuan S; Larsson SC
Review: METABOLISM: CLINICAL AND EXPERIMENTAL. 2023;144:155533
Epidemiology of sarcopenia: Prevalence, risk factors, and consequences
Yuan S; Larsson SC
Conference publication: GUT. 2023;72(SUPPL_2):a56-a57
Multisystem health consequences of nonalcoholic fatty liver disease: phenome-wide Mendelian randomization and disease-trajectory analyses
Jiang F; Wang L; Ding Y; Lu MY; Sun J; Zhao J; Chen J; Larsson S; Wang W; Yuan S; Li X
Conference publication: GUT. 2023;72(SUPPL_2):a26.2-a2a26
Identification of novel protein biomarkers and drug targets for colorectal cancer by integrating human plasma proteome with genome
Sun J; Zhao J; Xiao Q; Han F; Yuan S; Wei J; Larsson SC; Zhang H; Dunlop M; Farrington SM; Ding K-F; Theodoratou E; Li X
Review: DIABETOLOGIA. 2023;66(5):800-812
Causal factors underlying diabetes risk informed by Mendelian randomisation analysis: evidence, opportunities and challenges
Yuan S; Merino J; Larsson SC
Editorial comment: ALIMENTARY PHARMACOLOGY AND THERAPEUTICS. 2023;57(9):1034-1035
Editorial: in search of environmental risk factors of Crohn's disease and ulcerative colitis with mendelian randomisation-authors' reply
Chen J; Ruan X; Yuan S; Theodoratou E; Satsangi J; Li X
Letter: ALIMENTARY PHARMACOLOGY AND THERAPEUTICS. 2023;57(9):1048-1049
Letter: disentangling the role of redox-active compounds in the development of inflammatory bowel diseases-moving towards causal associations. Authors' reply
Chen J; Ruan X; Yuan S; Theodoratou E; Satsangi J; Li X
Preprint: BIORXIV. 2023
Apolipoprotein B and Interleukin 1 Receptor Antagonist: Reversing the Risk of Coronary Heart Disease
Yang F; Huangfu N; Shen J; Su P; Zhu L; Cui H; Yuan S
Preprint: MEDRXIV. 2023
Risk of incident cardiovascular disease among patients with gastrointestinal disorder: prospective cohort study of 340,862 individuals
Chen J; Sun Y; Fu T; Lu S; Shi W; Zhao J; Li S; Li X; Yuan S; Larsson S
Preprint: MEDRXIV. 2023
Sedentary lifestyle, Physical Activity, and Gastrointestinal Diseases: Evidence from Mendelian Randomization Analysis
Chen J; Ruan X; Fu T; Lu S; Gill D; He Z; Burgess S; Giovannucci E; Larsson S; Deng M; Yuan S; Li X
Editorial comment: ALIMENTARY PHARMACOLOGY AND THERAPEUTICS. 2023;57(5):575-576
Editorial: IBD and sleep-authors' reply
Yuan S; Chen J; Li X
Preprint: RESEARCH SQUARE. 2022
Identification of novel protein biomarkers and drug targets for colorectal cancer by integrating human plasma proteome with genome
Sun J; Zhao J; Jiang F; Wang L; Xiao Q; Han F; Chen J; Yuan S; Wei J; Larsson S; Honghe Z; Dunlop M; Farrington S; Ding K; Theodoratou E; Li X
Preprint: MEDRXIV. 2022
Birthweight, Childhood Obesity, Adulthood Obesity and Body Compositions, and Gastrointestinal Diseases: A Mendelian Randomization Study
Yuan S; Ruan X; Sun Y; Fu T; Zhao J; Deng M; Chen J; Li X; Larsson SC
Letter: FERTILITY AND STERILITY. 2022;118(6):1203-1204
Reply of the Authors: Smoking, alcohol, and coffee consumption and pregnancy loss: a Mendelian randomization investigation
Yuan S; Liu J; Larsson SC
Preprint: MEDRXIV. 2022
Gastrointestinal Diseases, Genetic Risk, and Incident Dementia: A Prospective Cohort Study in 352,463 Middle-Aged Adults
Yuan S; Dan L; Zhang Y; Wu J; Zhao J; Chen J; Li X; Kivipelto M; Larsson S
Preprint: RESEARCH SQUARE. 2022
Depression and 24 Gastrointestinal Diseases: A Mendelian Randomization Study
Yuan S; Ruan X; Chen J; Sun Y; Zhang Y; Zhao J; Wang X; Li X; Larsson S
Conference publication: EUROPEAN HEART JOURNAL. 2022;43:2432
Selenium concentration and cardiovascular disease risk: Mendelian randomization study
Yuan S; Mason AM; Bruzelius M; Akesson A; Burgess S; Larsson SC
Letter: CIRCULATION. GENOMIC AND PRECISION MEDICINE. 2022;15(5):e003830-475
Anthropometric Traits and Risk of Mitral Valve Prolapse: A Mendelian Randomization Study
Yuan S; Karhunen V; Larsson S; Gill D
Preprint: MEDRXIV. 2022
The contribution of genetic risk and lifestyle factors in the development of adult-onset inflammatory bowel disease: a prospective cohort study
Sun Y; Yuan S; Chen X; Sun J; Kalla R; Yu L; Wang L; Zhou X; Kong X; Hesketh T; Ho G-T; Ding K; Dunlop M; Larsson S; Satsangi J; Chen J; Wang X; Li X; Theodoratou E; Giovannucci E
Review: AMERICAN JOURNAL OF CLINICAL NUTRITION. 2022;116(1):230-243
Gut microbiota-derived metabolite trimethylamine-N-oxide and multiple health outcomes: an umbrella review and updated meta-analysis
Li D; Lu Y; Yuan S; Cai X; He Y; Chen J; Wu Q; He D; Fang A; Bo Y; Song P; Bogaert D; Tsilidis K; Larsson SC; Yu H; Zhu H; Theodoratou E; Zhu Y; Li X
Preprint: MEDRXIV. 2022
Sleep Duration, Quality, and Risk of Peripheral Artery Disease: Multinational Cohort and Mendelian Randomization Studies
Yuan S; Levin M; Titova O; Chen J; Sun Y; VA Million Veteran Program; Åkesson A; Li X; Damrauer S; Larsson S
Letter: EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (EJPC). 2022;29(1):e29-e31
Coffee consumption and risk of coronary artery disease
Zhang Z; Wang M; Yuan S; Liu X
Preprint: SSRN ELECTRONIC JOURNAL. 2022
Mendelian Randomization Analysis Revealed Pan-Effect of Smoking Instead of Alcohol Consumption on 24 Gastrointestinal Diseases
Yuan S; Chen J; Ruan X; Sun Y; Zhang K; Wang X; Li X; Gill D; Burgess S; Giovannucci E; Larsson S
Preprint: SSRN ELECTRONIC JOURNAL. 2022
Genetically Predicted High IGF-1 Levels Showed Protective Effects on COVID-19 Susceptibility and Hospitalization: A Mendelian Randomisation Study with Data from 60 Studies Across 25 Countries
Li X; Zhou Y; Yuan S; Zhou X; Wang L; Sun J; Yu L; Zhu J; Zhang H; Yang N; Dai S; Song P; Larsson S; Zhu Y; Li X; Theodoratou E
Letter: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2021;76(5):1559-1562
Assessing the protective role of allergic disease in gastrointestinal tract cancers using Mendelian randomization analysis
Yuan S; Vithayathil M; Kar S; Carter P; Mason AM; Xie S-H; Burgess S; Larsson SC
Preprint: SSRN ELECTRONIC JOURNAL. 2021
Association of Food Expenditure with Life Expectancy in the United States, 2001- 2014
Li Q; Yuan S; Yu Z; Larsson S; He Q
Review: SÃO PAULO MEDICAL JOURNAL. 2020;138(5):393-399
Can p63 serve as a biomarker for diagnosing giant cell tumor of bone? A systematic review and meta-analysis
Wan Z; Lee C-W; Yuan S; Lee OK-S
Preprint: MEDRXIV. 2020
Causal associations between salt intake with body mass, shape and composition: A two-sample Mendelian randomization study
Feng Q; Yuan S; Yang Q; Lu Y; Loos RJF; Li GHY; Fei Y; Tsoi MF; Cheung CL; Cheung BMY
Preprint: MEDRXIV. 2020
Health-related effects of education level: a Mendelian randomization study
Yuan S; Xiong Y; Michaëlsson M; Michaëlsson K; Larsson S
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Grants

From Normal Abdominal Aorta to Aneurysms: Unpacking Genetic Uniqueness and Refining Risk Prediction
American Heart Association
1 June 2024 - 31 May 2026

Employments

Affiliated to Research, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 2024-2026
Affiliated to Research, Institute of Environmental Medicine, Karolinska Institutet, 2024-2025

Degrees and Education

Degree Of Doctor Of Philosophy, Institute of Environmental Medicine, Karolinska Institutet, 2024
Degree Of Master Of Medical Science 120 Credits, Karolinska Institutet, 2020

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