Roberto Gramignoli

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: ADVANCED SCIENCE. 2025;12(3):e2407572
Chemogenomic Screening in a Patient-Derived 3D Fatty Liver Disease Model Reveals the CHRM1-TRPM8 Axis as a Novel Module for Targeted Intervention
Youhanna S; Kemas AM; Wright SC; Zhong Y; Klumpp B; Klein K; Motso A; Michel M; Ziegler N; Shang M; Sabatier P; Kannt A; Sheng H; Oliva-Vilarnau N; Buettner FA; Seashore-Ludlow B; Schreiner J; Windbergs M; Cornillet M; Bjorkstrom NK; Hulsmeier AJ; Hornemann T; Olsen JV; Wang Y; Gramignoli R; Sundstrom M; Lauschke VM
Article: JOURNAL OF MATERIALS CHEMISTRY B. 2024;12(36):8977-8992
Optimization of a nanoparticle uptake protocol applied to amniotic-derived cells: unlocking the therapeutic potential
Peserico A; Canciello A; Prencipe G; Gramignoli R; Melai V; Scortichini G; Bellocci M; Capacchietti G; Turriani M; Di Pancrazio C; Berardinelli P; Russo V; Mattioli M; Barboni B
Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2024;28(18):e18507
Wharton's Jelly mesenchymal stem cell-derived extracellular vesicles induce liver fibrosis-resolving phenotype in alternatively activated macrophages
Torabi S; Zarrabi M; Shekari F; Poorkazem H; Lotfinia M; Bencina S; Gramignoli R; Hassan M; Najimi M; Vosough M
Article: HEPATOLOGY. 2024;79(6):1337-1351
Wnt/β-catenin and NFκB signaling synergize to trigger growth-factor-free regeneration of adult primary human hepatocytes
Oliva-Vilarnau N; Beusch CM; Sabatier P; Sakaraki E; Tjaden A; Graetz L; Buettner FA; Dorotea D; Nguyen M; Bergqvist F; Sundstrom Y; Mueller S; Zubarev RA; Schulte G; Tredup C; Gramignoli R; Tietge UJF; Lauschke VM
Article: FRONTIERS IN IMMUNOLOGY. 2024;15:1469771
Immunomodulatory properties of extracellular vesicles isolated from bone marrow of patients with neuroblastoma: role of PD-L1 and HLA-G
Marimpietri D; Corrias MV; Tripodi G; Gramignoli R; Airoldi I; Morandi F
Article: SCIENCE ADVANCES. 2023;9(35):eadh1168
The cellular response to extracellular vesicles is dependent on their cell source and dose
Hagey DW; Ojansivu M; Bostancioglu BR; Saher O; Bost JP; Gustafsson MO; Gramignoli R; Svahn M; Gupta D; Stevens MM; Goergens A; EL Andaloussi S
Article: CELL JOURNAL. 2023;25(8):524-535
Umbilical Cord Blood-Derived Monocytes as A Reliable Source of Functional Macrophages for Biomedical Research
Torabi S; Zarrabi M; Hossein-Khannazer N; Lotfinia M; Nouri M; Gramignoli R; Hassan M; Vosough M
Article: JOURNAL OF TISSUE ENGINEERING. 2023;14:20417314231219813
Rat liver extracellular matrix and perfusion bioreactor culture promote human amnion epithelial cell differentiation towards hepatocyte-like cells
Campinoti S; Almeida B; Goudarzi N; Bencina S; Grundland Freile F; Mcquitty C; Natarajan D; Cox IJ; Le Guennec A; Khati V; Gaudenzi G; Gramignoli R; Urbani L
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022;23(23):14880
Effects of Pro-Inflammatory Cytokines on Hepatic Metabolism in Primary Human Hepatocytes
Gramignoli R; Ranade AR; Venkataramanan R; Strom SC
Article: STEM CELL RESEARCH & THERAPY. 2022;13(1):31
Human amniotic epithelial cell transplantation improves scar remodeling in a rabbit model of acute vocal fold injury: a pilot study
Tchoukalova YD; Zacharias SRC; Mitchell N; Madsen C; Myers CE; Gadalla D; Skinner J; Kopaczka K; Gramignoli R; Lott DG
Article: FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY. 2022;10:977590
Perinatal derivatives application: Identifying possibilities for clinical use
Gindraux F; Hofmann N; Agudo-Barriuso M; Antica M; Couto PS; Dubus M; Forostyak S; Girandon L; Gramignoli R; Jurga M; Liarte S; Navakauskiene R; Shablii V; Lafarge X; Nicolas FJ
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:840146
The Icarus Flight of Perinatal Stem and Renal Progenitor Cells Within Immune System
Picerno A; Castellano G; Curci C; Kopaczka K; Stasi A; Pertosa GB; Sabba C; Gesualdo L; Gramignoli R; Sallustio F
Article: CELL TRANSPLANTATION. 2022;31:9636897211069900
Procurement and Evaluation of Hepatocytes for Transplantation From Neonatal Donors After Circulatory Death
Bluhme E; Henckel E; Gramignoli R; Kjellin T; Hammarstedt C; Nowak G; Karadagi A; Johansson H; Jynge O; Soderstrom M; Fischler B; Strom S; Ellis E; Hallberg B; Jorns C
Article: BIO-DESIGN AND MANUFACTURING. 2021;4(4):790-805
Biofabrication of size-controlled liver microtissues incorporated with ECM-derived microparticles to prolong hepatocyte function
Heydari Z; Zarkesh I; Ghanian M-H; Aghdaei MH; Kotova S; Zahmatkesh E; Farzaneh Z; Piryaei A; Akbarzadeh I; Shpichka A; Gramignoli R; Timashev P; Baharvand H; Vosough M
Article: SCIENCE ADVANCES. 2021;7(30):eabg5733
Disorganization and degeneration of liver sympathetic innervations in nonalcoholic fatty liver disease revealed by 3D imaging
Adori C; Daraio T; Kuiper R; Barde S; Horvathova L; Yoshitake T; Ihnatko R; Valladolid-Acebes I; Vercruysse P; Wellendorf AM; Gramignoli R; Bozoky B; Kehr J; Theodorsson E; Cancelas JA; Mravec B; Jorns C; Ellis E; Mulder J; Uhlen M; Bark C; Hokfelt T
Article: ANTIOXIDANTS. 2021;10(7):1094
A Novel mRNA-Mediated and MicroRNA-Guided Approach to Specifically Eradicate Drug-Resistant Hepatocellular Carcinoma Cell Lines by Se-Methylselenocysteine
Selvam AK; Jawad R; Gramignoli R; Achour A; Salter H; Bjornstedt M
Article: STEM CELL RESEARCH & THERAPY. 2021;12(1):332
Amnion epithelial cells are an effective source of factor H and prevent kidney complement deposition in factor H-deficient mice
Casiraghi F; Ordonez PYR; Azzollini N; Todeschini M; Rottoli D; Donadelli R; Gramignoli R; Benigni A; Noris M; Remuzzi G
Article: CELLS. 2021;10(6):1274
Tissue-Specific Microparticles Improve Organoid Microenvironment for Efficient Maturation of Pluripotent Stem-Cell-Derived Hepatocytes
Zahmatkesh E; Ghanian MH; Zarkesh I; Farzaneh Z; Halvaei M; Heydari Z; Moeinvaziri F; Othman A; Ruoss M; Piryaei A; Gramignoli R; Yakhkeshi S; Nussler A; Najimi M; Baharvand H; Vosough M
Article: MOLECULAR THERAPY. 2021;29(5):1903-1917
Correction of a urea cycle defect after ex vivo gene editing of human hepatocytes
Zabulica M; Srinivasan RC; Akcakaya P; Allegri G; Bestas B; Firth M; Hammarstedt C; Jakobsson T; Jakobsson T; Ellis E; Jorns C; Makris G; Scherer T; Rimann N; van Zuydam NR; Gramignoli R; Forslow A; Engberg S; Maresca M; Rooyackers O; Thony B; Haberle J; Rosen B; Strom SC
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(3):1217
Gene Editing Correction of a Urea Cycle Defect in Organoid Stem Cell Derived Hepatocyte-like Cells
Zabulica M; Jakobsson T; Ravaioli F; Vosough M; Gramignoli R; Ellis E; Rooyackers O; Strom SC
Article: CELLS. 2020;9(9):E2123-2123
Human Amnion Epithelial Cells Impair T Cell Proliferation: The Role of HLA-G and HLA-E Molecules
Morandi F; Marimpietri D; Goergens A; Gallo A; Srinivasan RC; El-Andaloussi S; Gramignoli R
Article: CELLS. 2020;9(7):E1696-1696
Effects of Cryogenic Storage on Human Amnion Epithelial Cells
Srinivasan RC; Strom SC; Gramignoli R
Article: NUTRIENTS. 2020;12(2):E277-277
Aging and Caloric Restriction Modulate the DNA Methylation Profile of the Ribosomal RNA Locus in Human and Rat Liver
Gensous N; Ravaioli F; Pirazzini C; Gramignoli R; Ellis E; Storci G; Capri M; Strom S; Laconi E; Franceschi C; Garagnani P; Marongiu F; Bacalini MG
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2019;861:172597
Assessment of animal experimental models of toxic liver injury in the context of their potential application as preclinical models for cell therapy
Czekaj P; Krol M; Limanowka L; Michalik M; Lorek K; Gramignoli R
Article: JOURNAL OF CELLULAR BIOCHEMISTRY. 2019;120(10):16624-16633
Prenatal liver stromal cells: Favorable feeder cells for long-term culture of hepatic progenitor cells
Feizi Z; Zahmatkesh E; Farzaneh Z; Piryaei A; Gramignoli R; Nussler AK; Baharvand H; Vosough M
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2019;859:172545
Increased immunomodulatory capacity of human amniotic cells after activation by pro-inflammatory chemokines
Kolanko E; Kopaczka K; Koryciak-Komarska H; Czech E; Szmytkowska P; Gramignoli R; Czekaj P
Article: EXPERIMENTAL AND CLINICAL TRANSPLANTATION. 2019;17(4):513-521
Complications and Outcomes of Endoscopic Treatment in a Cohort of Patients With Biliary Stenosis After Orthotopic Liver Transplant: A Retrospective Observational Study
Bortolasi L; Violi P; Carraro A; Montin U; Cerofolini A; Munari A; Eccher A; Gramignoli R; Bovo C; Tedeschi U
Article: STEM CELLS AND DEVELOPMENT. 2019;28(14):907-919
Guide to the Assessment of Mature Liver Gene Expression in Stem Cell-Derived Hepatocytes
Zabulica M; Srinivasan RC; Vosough M; Hammarstedt C; Wu T; Gramignoli R; Ellis E; Kannisto K; de l'Hortet AC; Takeishi K; Soto-Gutierrez A; Strom SC
Article: INTERNATIONAL JOURNAL OF CANCER. 2019;144(10):2613-2624
Targeting HSP90 with the small molecule inhibitor AUY922 (luminespib) as a treatment strategy against hepatocellular carcinoma
Augello G; Emma MR; Cusimano A; Azzolina A; Mongiovi S; Puleio R; Cassata G; Gulino A; Belmonte B; Gramignoli R; Strom SC; McCubrey JA; Montalto G; Cervello M
Article: JOURNAL OF IMMUNOLOGY. 2019;202(3):724-735
Ectonucleotidase Expression on Human Amnion Epithelial Cells: Adenosinergic Pathways and Dichotomic Effects on Immune Effector Cell Populations
Morandi F; Horenstein AL; Quarona V; Faini AC; Castella B; Srinivasan RC; Strom SC; Malavasi F; Gramignoli R
Article: PLOS ONE. 2019;14(4):e0215490
Applying hydrodynamic pressure to efficiently generate induced pluripotent stem cells via reprogramming of centenarian skin fibroblasts
Vosough M; Ravaioli F; Zabulica M; Capri M; Garagnani P; Franceschi C; Piccand J; Kraus MR-C; Kannisto K; Gramignoli R; Strom SC
Article: CYTOTHERAPY. 2019;21(1):113-124
Evaluation of different routes of administration and biodistribution of human amnion epithelial cells in mice
Srinivasan RC; Kannisto K; Strom SC; Gramignoli R
Article: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2019;74(1):1-8
Molecular Aging of Human Liver: An Epigenetic/Transcriptomic Signature
Bacalini MG; Franceschi C; Gentilini D; Ravaioli F; Zhou X; Remondini D; Pirazzini C; Giuliani C; Marasco E; Gensous N; Di Blasio AM; Ellis E; Gramignoli R; Castellani G; Capri M; Strom S; Nardini C; Cescon M; Grazi GL; Garagnani P
Article: PLACENTA. 2017;59:139-145
Differentiation of amniotic epithelial cells into various liver cell types and potential therapeutic applications
Fanti M; Gramignoli R; Serra M; Cadoni E; Strom SC; Marongiu F
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2017;51(2):533-544
Oleocanthal exerts antitumor effects on human liver and colon cancer cells through ROS generation
Cusimano A; Balasus D; Azzolina A; Augello G; Emma MR; Di Sano C; Gramignoli R; Strom SC; McCubrey JA; Montalto G; Cervello M
Article: JOURNAL OF HEPATOLOGY. 2017;66(5):987-1000
Host conditioning and rejection monitoring in hepatocyte transplantation in humans
Soltys KA; Setoyama K; Tafaleng EN; Gutierrez AS; Fong J; Fukumitsu K; Nishikawa T; Nagaya M; Sada R; Haberman K; Gramignoli R; Dorko K; Tahan V; Dreyzin A; Baskin K; Crowley JJ; Quader MA; Deutsch M; Ashokkumar C; Shneider BL; Squires RH; Ranganathan S; Reyes-Mugica M; Dobrowolski SF; Mazariegos G; Elango R; Stolz DB; Strom SC; Vockley G; Roy-Chowdhury J; Cascalho M; Guha C; Sindhi R; Platt JL; Fox IJ
Article: PLOS ONE. 2017;12(5):e0177279
Exogenous alpha 1-antitrypsin down-regulates SERPINA1 expression
Karadagi A; Johansson H; Zemack H; Salipalli S; Mork L-M; Kannisto K; Jorns C; Gramignoli R; Strom S; Stokkeland K; Ericzon B-G; Jonigk D; Janciauskiene S; Nowak G; Ellis ECS
Article: HUMAN IMMUNOLOGY. 2016;77(9):734-739
Human amnion epithelial cells expressing HLA-G as novel cell-based treatment for liver disease
Strom SC; Gramignoli R
Article: DRUG METABOLISM AND DISPOSITION. 2016;44(7):1027-1037
Role of Chromatin Structural Changes in Regulating Human CYP3A Ontogeny
Giebel NL; Shadley JD; McCarver DG; Dorko K; Gramignoli R; Strom SC; Yan K; Simpson PM; Hines RN
Article: CURRENT PROTOCOLS IN STEM CELL BIOLOGY. 2016;37:1E.10.1-1E.10.13
Isolation of Human Amnion Epithelial Cells According to Current Good Manufacturing Procedures.
Gramignoli R; Srinivasan RC; Kannisto K; Strom SC
Article: AMERICAN JOURNAL OF TRANSPLANTATION. 2016;16(3):1021-1030
De Novo Donor-Specific HLA Antibody Formation in Two Patients With Crigler-Najjar Syndrome Type I Following Human Hepatocyte Transplantation With Partial Hepatectomy Preconditioning
Jorns C; Nowak G; Nemeth A; Zemack H; Mork L-M; Johansson H; Gramignoli R; Watanabe M; Karadagi A; Alheim M; Hauzenberger D; van Dijk R; Bosma PJ; Ebbesen F; Szakos A; Fischler B; Strom S; Ellis E; Ericzon B-G
Article: CURRENT PROTOCOLS IN TOXICOLOGY / EDITORIAL BOARD, MAHIN D. MAINES (EDITOR-IN-CHIEF) ... [ET AL.]. 2014;62:14.12.1-14.1223
The history and use of human hepatocytes for the treatment of liver diseases: the first 100 patients.
Hansel MC; Gramignoli R; Skvorak KJ; Dorko K; Marongiu F; Blake W; Davila J; Strom SC
Article: CELL TRANSPLANTATION. 2014;23(1):27-38
Increased Reprogramming of Human Fetal Hepatocytes Compared With Adult Hepatocytes in Feeder-Free Conditions
Hansel MC; Gramignoli R; Blake W; Davila J; Skvorak K; Dorko K; Tahan V; Lee BR; Tafaleng E; Guzman-Lepe J; Soto-Gutierrez A; Fox IJ; Strom SC
Article: CELL TRANSPLANTATION. 2014;23(12):1545-1556
Rapid and Sensitive Assessment of Human Hepatocyte Functions
Gramignoli R; Tahan V; Dorko K; Venkataramanan R; Fox IJ; Ellis ECS; Vosough M; Strom SC
Article: CELL TRANSPLANTATION. 2014;23(12):1537-1544
Potential Barriers to Human Hepatocyte Transplantation in MUP-uPA^tg(+/+)Rag2^-/-γC^-/- Mice
Komori J; De Ward AD; Gramignoli R; Strom SC; Fontes P; Lagasse E
Article: CELL TRANSPLANTATION. 2014;23(9):1143-1151
Hypothermic Storage of Human Hepatocytes for Transplantation
Gramignoli R; Dorko K; Tahan V; Skvorak KJ; Ellis E; Jorns C; Ericzon B-G; Fox IJ; Strom SC
Article: CELL TRANSPLANTATION. 2014;23(8):1009-1018
Strategies for Short-Term Storage of Hepatocytes for Repeated Clinical Infusions
Jorns C; Gramignoli R; Saliem M; Zemack H; Mork L-M; Isaksson B; Nowak G; Ericzon B-G; Strom S; Ellis E
Article: STEM CELLS AND DEVELOPMENT. 2013;22:96-102
Translation of Amnion Stem Cells to the Clinic
Strom SC; Skvorak K; Gramignoli R; Marongiu F; Miki T
Article: DRUG METABOLISM AND DISPOSITION. 2013;41(10):1843-1851
Ritonavir and Efavirenz Significantly Alter the Metabolism of Erlotinib-an Observation in Primary Cultures of Human Hepatocytes That Is Relevant to HIV Patients with Cancer
Pillai VC; Venkataramanan R; Parise RA; Christner SM; Gramignoli R; Strom SC; Rudek MA; Beumer JH
Article: STEM CELL RESEARCH. 2013;11(1):563-573
New potential cell source for hepatocyte transplantation: Discarded livers from metabolic disease liver transplants
Gramignoli R; Tahan V; Dorko K; Skvorak KJ; Hansel MC; Zhao W; Venkataramanan R; Ellis ECS; Jorns C; Ericzon B-G; Rosenborg S; Kuiper R; Soltys KA; Mazariegos GV; Fox IJ; Wilson EM; Grompe M; Strom SC
Article: MOLECULAR GENETICS AND METABOLISM. 2013;109(2):132-138
Improved Amino Acid, Bioenergetic Metabolite and Neurotransmitter Profiles following Human Amnion Epithelial Cell Transplant in Intermediate Maple Syrup Urine Disease Mice
Skvorak KJ; Dorko K; Marongiu F; Tahan V; Hansel MC; Gramignoli R; Arning E; Bottiglieri T; Gibson KM; Strom SC
Article: HEPATOLOGY. 2013;57(3):1017-1023
Placental stem cell correction of murine intermediate maple syrup urine disease
Skvorak KJ; Dorko K; Marongiu F; Tahan V; Hansel MC; Gramignoli R; Gibson KM; Strom SC
Article: DRUG METABOLISM AND DISPOSITION. 2013;41(2):296-304
Hepatobiliary Disposition of 17-OHPC and Taurocholate in Fetal Human Hepatocytes: A Comparison with Adult Human Hepatocytes
Sharma S; Ellis ECS; Gramignoli R; Dorko K; Tahan V; Hansel M; Mattison DR; Caritis SN; Hines RN; Venkataramanan R; Strom SC
Article: MOLECULAR ENDOCRINOLOGY. 2013;27(1):106-115
Regulation of the Human Hydroxysteroid Sulfotransferase (SULT2A1) by RORα and RORγ and Its Potential Relevance to Human Liver Diseases
Ou Z; Shi X; Gilroy RK; Kirisci L; Romkes M; Lynch C; Wang H; Xu M; Jiang M; Ren S; Gramignoli R; Strom SC; Huang M; Xie W
Article: DIABETES. 2012;61(8):2004-2015
ChREBP Mediates Glucose-Stimulated Pancreatic β-Cell Proliferation
Metukuri MR; Zhang P; Basantani MK; Chin C; Stamateris RE; Alonso LC; Takane KK; Gramignoli R; Strom SC; O'Doherty RM; Stewart AF; Vasavada RC; Garcia-Ocana A; Scott DK
Article: CELL TRANSPLANTATION. 2012;21(6):1245-1260
Development and Application of Purified Tissue Dissociation Enzyme Mixtures for Human Hepatocyte Isolation
Gramignoli R; Green ML; Tahan V; Dorko K; Skvorak KJ; Marongiu F; Zao W; Venkataramanan R; Ellis ECS; Geller D; Breite AG; Dwulet FE; McCarthy RC; Strom SC
Article: DIABETES. 2011;60(11):2763-2774
FoxO6 Integrates Insulin Signaling With Gluconeogenesis in the Liver
Kim DH; Perdomo G; Zhang T; Slusher S; Lee S; Phillips BE; Fan Y; Giannoukakis N; Gramignoli R; Strom S; Ringquist S; Dong HH
Article: TISSUE ENGINEERING PART C-METHODS. 2011;17(6):677-686
A Whole-Organ Regenerative Medicine Approach for Liver Replacement
Soto-Gutierrez A; Zhang L; Medberry C; Fukumitsu K; Faulk D; Jiang H; Reing J; Gramignoli R; Komori J; Ross M; Nagaya M; Lagasse E; Stolz D; Strom SC; Fox IJ; Badylak SF
Article: HEPATOLOGY. 2011;53(5):1719-1729
Hepatic Differentiation of Amniotic Epithelial Cells
Marongiu F; Gramignoli R; Dorko K; Miki T; Ranade AR; Serra MP; Doratiotto S; Sini M; Sharma S; Mitamura K; Sellaro TL; Tahan V; Skvorak KJ; Ellis ECS; Badylak SF; Davila JC; Hines R; Laconi E; Strom SC
Article: MOLECULAR ENDOCRINOLOGY. 2011;25(4):584-596
MicroRNA hsa-miR-613 Targets the Human LXRα Gene and Mediates a Feedback Loop of LXRα Autoregulation
Ou Z; Wada T; Gramignoli R; Li S; Strom SC; Huang M; Xie W
Article: DIGESTIVE DISEASES AND SCIENCES. 2011;56(3):715-720
Melatonin Expresses Powerful Anti-inflammatory and Antioxidant Activities Resulting in Complete Improvement of Acetic-Acid-Induced Colitis in Rats
Tahan G; Gramignoli R; Marongiu F; Aktolga S; Cetinkaya A; Tahan V; Dorko K
Article: ENDOCRINOLOGY. 2010;151(8):3521-3535
FoxO1 Links Hepatic Insulin Action to Endoplasmic Reticulum Stress
Kamagate A; Kim DH; Zhang T; Slusher S; Gramignoli R; Strom SC; Bertera S; Ringquist S; Dong HH
Article: CURRENT PROTOCOLS IN STEM CELL BIOLOGY. 2010;Chapter 1:Unit-1E.5
Isolation of amniotic mesenchymal stem cells.
Marongiu F; Gramignoli R; Sun Q; Tahan V; Miki T; Dorko K; Ellis E; Strom SC
Article: DIGESTIVE AND LIVER DISEASE. 2006;38(12):905-911
Animal model for liver cell banking from non-heart beating donors after prolonged ischaemia time
Porretti L; Gatti S; Gramignoli R; Colombo F; Lopa R; Cattaneo A; Scalamogna M; Colombo G; Rossi G; Bonino F; Rebulla P; Prati D
Article: HAEMATOLOGICA. 2004;89(10):1179-1186
Clinical and histological characterization of liver disease in patients with transfusion-dependent β-thalassemia.: A multicenter study of 117 cases
Prati D; Maggioni M; Milani S; Cerino M; Cianciulli P; Coggi G; Forni GL; Magnano C; Meo A; Gramignoli R; Rebulla P; Fiorelli G; Cappellini MD
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Alla övriga publikationer

Review: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2025;29(3):e70390
Standard Protocols for Characterising Primary and In Vitro-Generated Human Hepatocytes
Heydari Z; Gramignoli R; Piryaei A; Zahmatkesh E; Pooyan P; Seydi H; Nussler A; Szkolnicka D; Rashidi H; Najimi M; Hay DC; Vosough M
Review: STEM CELLS TRANSLATIONAL MEDICINE. 2024;13(1):14-29
Expert Revision of Key Elements for Clinical-Grade Production and Qualification of Perinatal Derivatives
Gramignoli R; Hofmann N; Agudo-Barriuso M; Antica M; Flores AI; Girandon L; Kerdjoudj H; Navakauskiene R; Schiavi J; Scholz H; Shablii V; Lafarge X; Nicolas FJ; Gindraux F
Review: CELLS. 2023;12(16):2114
Amniotic Membrane and Its Derivatives: Novel Therapeutic Modalities in Liver Disorders
Arki MK; Moeinabadi-Bidgoli K; Hossein-Khannazer N; Gramignoli R; Najimi M; Vosough M
Review: HUMAN IMMUNOLOGY. 2023;84(8):359-365
Immune-regulatory properties carried by human amnion epithelial cells: Focus on the role of HLA-G and adenosinergic ectoenzymes
Morandi F; Airoldi I; Faini A; Horenstein A; Malavasi F; Matysiak N; Kopaczka K; Marimpietri D; Gramignoli R
Review: STEM CELLS TRANSLATIONAL MEDICINE. 2023;12(5):258-265
Expert Consideration on Regulatory Aspects for Perinatal Derivatives in Clinical Settings
Hofmann N; Lafarge X; Antica M; Ferry N; Girandon L; Gramignoli R; Jurga M; Kerdjoudj H; Navakauskiene R; Schiavi J; Shablii V; Nicolas FJ; Gindraux F
Review: SEMINARS IN LIVER DISEASE. 2023;43(02):149-162
Hepatic Innervations and Nonalcoholic Fatty Liver Disease
Adori M; Bhat S; Gramignoli R; Valladolid-Acebes I; Bengtsson T; Uhlen M; Adori C
Review: EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY. 2023;17(3):237-249
Cell and cell-derivative-based therapy for liver diseases: current approaches and future promises
Zahmatkesh E; Rad NK; Hossein-Khannazer N; Mohamadnejad M; Gramignoli R; Najimi M; Malekzadeh R; Hassan M; Vosough M
Editorial comment: JOURNAL OF HEPATOLOGY. 2023;78(1):12-15
New cell-based approaches for liver disorders: From experimental to validated clinical treatment
Gramignoli R
Review: BIOENGINEERING-BASEL. 2022;9(8):392
Novel Gene-Correction-Based Therapeutic Modalities for Monogenic Liver Disorders
Ghasemzad M; Hashemi M; Lavasani ZM; Hossein-khannazer N; Bakhshandeh H; Gramignoli R; Alikhani HK; Najimi M; Nikeghbalian S; Vosough M
Review: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022;23(15):8570
Application of Perinatal Derivatives on Oncological Preclinical Models: A Review of Animal Studies
Teixo R; Pires AS; Pereira E; Serambeque B; Marques IA; Laranjo M; Mojsilovic S; Gramignoli R; Ponsaerts P; Schoeberlein A; Botelho MF
Review: CELLS. 2022;11(7):1074
Extraembryonic Mesenchymal Stromal/Stem Cells in Liver Diseases: A Critical Revision of Promising Advanced Therapy Medicinal Products
Shahrbaf MA; Nouri M; Zarrabi M; Gramignoli R; Vosough M
Editorial comment: FRONTIERS IN MEDICINE. 2022;9:901003
Editorial: Repair and regenerative mechanisms by stem/progenitor cells and secretome: The golden twenties of translational medicine
Gramignoli R; Sallustio F; Widera D
Review: FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY. 2022;10:961987
General consensus on multimodal functions and validation analysis of perinatal derivatives for regenerative medicine applications
Pozzobon M; D'Agostino S; Roubelakis MGG; Cargnoni A; Gramignoli R; Wolbank S; Gindraux F; Bollini S; Kerdjoudj H; Fenelon M; Di Pietro R; Basile M; Borutinskaite V; Piva R; Schoeberlein A; Eissner G; Giebel B; Ponsaerts P
Review: TRENDS IN ENDOCRINOLOGY AND METABOLISM. 2021;32(9):731-745
Metabolic hallmarks of liver regeneration
Solhi R; Lotfinia M; Gramignoli R; Najimi M; Vosough M
Editorial comment: CYTOTHERAPY. 2020;22(2):53-56
Identification of hurdles in the development of cell-based therapies
Rotolo A; Chabannon C; Gramignoli R
Review: CELLS. 2020;9(2):E304-304
Tissue Engineering in Liver Regenerative Medicine: Insights into Novel Translational Technologies
Heydari Z; Najimi M; Mirzaei H; Shpichka A; Ruoss M; Farzaneh Z; Montazeri L; Piryaei A; Timashev P; Gramignoli R; Nussler A; Baharvand H; Vosough M
Review: CELLS. 2019;8(12):E1527-1527
CD38, a Receptor with Multifunctional Activities: From Modulatory Functions on Regulatory Cell Subsets and Extracellular Vesicles, to a Target for Therapeutic Strategies
Morandi F; Airoldi I; Marimpietri D; Bracci C; Faini AC; Gramignoli R
Published conference paper: JOURNAL OF INHERITED METABOLIC DISEASE. 2019;42(6):1054-1063
A liver-humanized mouse model of carbamoyl phosphate synthetase 1-deficiency
Srinivasan RC; Zabulica M; Hammarstedt C; Wu T; Gramignoli R; Kannisto K; Ellis E; Karadagi A; Fingerhut R; Allegri G; Rufenacht V; Thony B; Haberle J; Nuoffer J-M; Strom SC
Meeting abstract: TRANSPLANTATION. 2019;103(9):S21
CPS-1 Humanized Liver in FRGN Mouse as Model for Genetic Disorder
Srinivasan R; Zabulica M; Hammerstadt C; Gramignoli R; Strom S
Meeting abstract: TRANSPLANTATION. 2019;103(9):S11
Molecular Pathways in Support of Allogenic Human Amnion Epithelial Cell Transplantation for Liver Disease Without Immunosuppression
Gramignoli R; Morandi F; Horenstein A; Srinivasan R; Malavasi F; Strom S
Meeting abstract: CYTOTHERAPY. 2019;21(5):S26
CELLULAR MECHANISM IN SUPPORT OF ALLOGENIC HUMAN AMNION EPITHELIAL CELL TRANSPLANTATION WITHOUT IMMUNOSUPPRESSION
Gramignoli R; Morandi F; Horenstein A; Strunz B; Srinivasan RC; Malavasi F; Strom SC
Review: STEM CELLS INTERNATIONAL. 2019;2019:6795845-12
Role of Toll-Like Receptors in Actuating Stem/Progenitor Cell Repair Mechanisms: Different Functions in Different Cells
Sallustio F; Curci C; Stasi A; De Palma G; Divella C; Gramignoli R; Castellano G; Gallone A; Gesualdo L
Meeting abstract: JOURNAL OF HEPATOLOGY. 2019;70(1):E582
Liver humanized mouse as models for human metabolic liver diseases
Strom S; Srinivasan RC; Zabulica M; Hammarstedt C; Wu T; Gramignoli R; Kannisto K; Ellis E; Karadagi A; Haberle J; Allegri G; Ruefenacht V; Thony B; Fingerhut R; Nuoffer J-M
Editorial comment: FRONTIERS IN MEDICINE. 2019;6:11
Editorial: Tissue Repair and Regenerative Mechanisms by Stem/Progenitor Cells and Their Secretome
Gramignoli R; Sallustio F; Widera D; Raschzok N
Meeting abstract: JOURNAL OF HEPATOLOGY. 2017;66(1):S181-S182
GMP-level isolation, quality assessment and biosafety distribution evaluation on human amnion epithelial cell for cell-based therapies
Gramignoli R; Srinivasan RC; Kristina K; Askelof U; Zabulica M; Strom SC
Review: CURRENT PROTOCOLS IN TOXICOLOGY / EDITORIAL BOARD, MAHIN D. MAINES (EDITOR-IN-CHIEF) ... [ET AL.]. 2016;67:14.13.1-14.13.27
The Use of Induced Pluripotent Stem Cells for the Study and Treatment of Liver Diseases.
Hansel MC; Davila JC; Vosough M; Gramignoli R; Skvorak KJ; Dorko K; Marongiu F; Blake W; Strom SC
Meeting abstract: CYTOTHERAPY. 2015;17(6):S74
ANALYSIS OF GENE EXPRESSIONS AND METABOLIC ACTIVITIES IN FETAL AND POSTNATAL HUMAN HEPATOCYTES FOR CLINICAL THERAPY
Gramignoli R; Kannisto K; Srinivasan RC; Miki T; Strom SC
Review: EUROPEAN SURGICAL RESEARCH. 2015;54(3-4):162-177
Clinical Hepatocyte Transplantation: Practical Limits and Possible Solutions
Gramignoli R; Vosough M; Kannisto K; Srinivasan RC; Strom SC
Meeting abstract: JOURNAL OF HEPATOLOGY. 2014;60(1):S277-S278
ANALYSIS OF METABOLIC ACTIVITIES IN FETAL AND ADULT HUMAN HEPATOCYTES FOR CLINICAL THERAPY
Gramignoli R; Strom SC
Meeting abstract: JOURNAL OF HEPATOLOGY. 2014;60(1):S104
EFFECT OF PURIFIED ALPHA 1-ANTITRYPSIN (AAT) ON EXPRESSION OF AAT IN NORMAL (PIMM) AND AAT DEFICIENT (PIZZ) PRIMARY HUMAN HEPATOCYTES
Ellis ECS; Johansson H; Zemack H; Jorns C; Gramignoli R; Strom S; Nowak G; Ericzon B-G
Meeting abstract: JOURNAL OF HEPATOLOGY. 2014;60(1):S18
CORRECTION OF ACUTE LIVER FAILURE AND PHENYLKETONURIA BY HUMAN AMNION EPITHELIAL STEM CELL THERAPY
Strom SC; Skvorak KJ; Tahan V; Gramignoli R
Meeting abstract: TRANSPLANTATION. 2012;94(10):282
Human Placental Stem Cell Transplant Lengthens Survival and Corrects Biophysical Disruptions in a Murine Model of Maple Syrup Urine Disease
Skvorak KJ; Dorko K; Marongiu F; Tahan V; Hansel MC; Gramignoli R; Arning E; Bottiglieri T; Gibson KM; Strom SC
Meeting abstract: TRANSPLANTATION. 2012;94(10):281
Hepatocyte Transplantation Improves Blood and Brain Phenylalanine and Neurotransmitter Imbalances in a Mouse Model of Phenylketonuria (PKU)
Skvorak KJ; Dorko K; Hansel MC; Tahan V; Gramignoli R; Arning E; Bottiglieri T; Gibson KM; Strom SC
Meeting abstract: TRANSPLANTATION. 2012;94(10):1011
Effects of Pro-Inflammatory Cytokines on Hepatocyte Drug and Ammonia Metabolism
Gramignoli R; Tahan V; Dorko K; Geller DA; Mazariegos G; Fox IJ; Ellis EC; Strom SC
Meeting abstract: TRANSPLANTATION. 2012;94(10):214
Evaluation of Hepatocytes from Explanted-Diseased Livers for Transplantation
Gramignoli R; Tahan V; Dorko K; Skvorak KJ; Hansel MC; Mazariegos G; Soltys K; Fox IJ; Jorns C; Ericzon B-G; Ellis EC; Strom SC
Meeting abstract: TRANSPLANTATION. 2012;94(10):1005
Evaluation of Hepatocytes from Explanted-Diseased Livers for Transplantation
Gramignoli R; Tahan V; Dorko K; Skvorak KJ; Hansel MC; Mazariegos G; Soltys K; Fox IJ; Jorns C; Ericzon B-G; Ellis EC; Strom SC
Meeting abstract: TRANSPLANTATION. 2012;94(10):1006
Rapid Assessment of Viability and Function of Human Hepatocytes for Possible Transplantation
Gramignoli R; Dorko K; Tahan V; Skvorak KJ; Geller D; Fox IJ; Jorns C; Ericzon B-G; Ellis EC; Strom SC
Meeting abstract: TRANSPLANTATION. 2012;94(10):215
Rapid Assessment of Viability and Function of Human Hepatocytes for Possible Transplantation
Gramignoli R; Dorko K; Tahan V; Skvorak KJ; Geller D; Fox IJ; Jorns C; Ericzon B-G; Ellis EC; Strom SC
Meeting abstract: DIGESTIVE AND LIVER DISEASE. 2011;43:S96
Isolation and evaluation of human hepatocytes for cell-based therapy
Gramignoli R; Marongiu F; Tahan V; Dorko K; Geller D; Venkataramanan R; D'Antiga L; Ellis ECS; Strom SC
Review: METHODS IN MOLECULAR BIOLOGY. 2009;481:155-168
Production of hepatocyte-like cells from human amnion.
Miki T; Marongiu F; Ellis ECS; Dorko K; Mitamura K; Ranade A; Gramignoli R; Davila J; Strom SC
Meeting abstract: BLOOD. 2004;104(11):131B
Expression of CXCR4 on intrahepatic stem cells from organ donors and patients with chronic liver disease
Porretti L; Lopa R; Gramignoli R; Ambrosone A; Mosca A; Cattaneo A; Scalamogna M; Gatti S; Rossi G; Colli A; Prati D
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