Richard Rosenquist Brandell | Karolinska Institutet

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Artiklar

Article: LEUKEMIA. 2024;38(6):1287-1298

IκBε deficiency accelerates disease development in chronic lymphocytic leukemia.

Bordini J; Lenzi C; Frenquelli M; Morabito A; Pseftogas A; Belloni D; Mansouri L; Tsiolas G; Perotta E; Ranghetti P; Gandini F; Genova F; Hägerstrand D; Gavriilidis G; Keisaris S; Pechlivanis N; Davi F; Kay NE; Langerak AW; Pospisilova S; Scarfò L; Makris A; Psomopoulos FE; Stamatopoulos K; Rosenquist R; Campanella A; Ghia P
Article: JOURNAL OF INTERNAL MEDICINE. 2024;295(6):785-803

High-throughput molecular assays for inclusion in personalised oncology trials - State-of-the-art and beyond.

Edsjö A; Russnes HG; Lehtiö J; Tamborero D; Hovig E; Stenzinger A; Rosenquist R; PCM4EU consortium
Article: NATURE GENETICS. 2024;56(5):733-736

The 1+Million Genomes Minimal Dataset for Cancer.

Riba M; Sala C; Culhane AC; Flobak Å; Patocs A; Boye K; Plevova K; Pospíšilová Š; Gandolfi G; Morelli MJ; Bucci G; Edsjö A; Lassen U; Al-Shahrour F; Lopez-Bigas N; Hovland R; Cuppen E; Valencia A; Poirel HA; Rosenquist R; Scollen S; Arenas Marquez J; Belien J; De Nicolo A; De Maria R; Torrents D; Tonon G
Article: THE LANCET REGIONAL HEALTH - EUROPE. 2024;39:100881

Diagnostic yield and clinical impact of germline sequencing in children with CNS and extracranial solid tumors-a nationwide, prospective Swedish study.

Tesi B; Robinson KL; Abel F; Díaz de Ståhl T; Orrsjö S; Poluha A; Hellberg M; Wessman S; Samuelsson S; Frisk T; Vogt H; Henning K; Sabel M; Ek T; Pal N; Nyman P; Giraud G; Wille J; Pronk CJ; Norén-Nyström U; Borssén M; Fili M; Stålhammar G; Herold N; Tettamanti G; Maya-Gonzalez C; Arvidsson L; Rosén A; Ekholm K; Kuchinskaya E; Hallbeck A-L; Nordling M; Palmebäck P; Kogner P; Smoler GK; Lähteenmäki P; Fransson S; Martinsson T; Shamik A; Mertens F; Rosenquist R; Wirta V; Tham E; Grillner P; Sandgren J; Ljungman G; Gisselsson D; Taylan F; Nordgren A
Article: JOURNAL OF CLINICAL ONCOLOGY. 2024;42(4):452-466

Genetic Characterization of Primary Mediastinal B-Cell Lymphoma: Pathogenesis and Patient Outcomes.

Noerenberg D; Briest F; Hennch C; Yoshida K; Hablesreiter R; Takeuchi Y; Ueno H; Staiger AM; Ziepert M; Asmar F; Locher BN; Toth E; Weber T; Amini R-M; Klapper W; Bouzani M; Poeschel V; Rosenwald A; Held G; Campo E; Ishaque N; Stamatopoulos K; Kanellis G; Anagnostopoulos I; Bullinger L; Goldschmidt N; Zinzani PL; Bödör C; Rosenquist R; Vassilakopoulos TP; Ott G; Ogawa S; Damm F
Article: LEUKEMIA. 2023;37(11):2237-2249

Frequent ZNF217 mutations lead to transcriptional deregulation of interferon signal transduction via altered chromatin accessibility in B cell lymphoma.

Briest F; Noerenberg D; Hennch C; Yoshida K; Hablesreiter R; Nimo J; Sasca D; Kirchner M; Mansouri L; Inoue Y; Wiegand L; Staiger AM; Casadei B; Korkolopoulou P; Weiner J; Lopez-Guillermo A; Warth A; Schneider T; Nagy Á; Klapper W; Hummel M; Kanellis G; Anagnostopoulos I; Mertins P; Bullinger L; Rosenquist R; Vassilakopoulos TP; Ott G; Ogawa S; Damm F
Article: HAEMATOLOGICA. 2023;108(10):2664-2676

Subgroup-specific gene expression profiles and mixed epistasis in chronic lymphocytic leukemia.

Lütge A; Lu J; Hüllein J; Walther T; Sellner L; Wu B; Rosenquist R; Oakes CC; Dietrich S; Huber W; Zenz T
Article: GENES CHROMOSOMES & CANCER. 2023;62(9):557-563

Real-world data for precision cancer medicine-A European perspective.

Christopoulos P; Schlenk R; Kazdal D; Blasi M; Lennerz J; Shah R; Budczies J; Malek N; Fröhling S; Rosenquist R; Schirmacher P; Bozorgmehr F; Kuon J; Reck M; Thomas M; Stenzinger A
Article: JOURNAL OF CLINICAL INVESTIGATION. 2023;133(13):e166070

Tumor-activated lymph node fibroblasts suppress T cell function in diffuse large B cell lymphoma.

Apollonio B; Spada F; Petrov N; Cozzetto D; Papazoglou D; Jarvis P; Kannambath S; Terranova-Barberio M; Amini R-M; Enblad G; Graham C; Benjamin R; Phillips E; Ellis R; Nuamah R; Saqi M; Calado DP; Rosenquist R; Sutton LA; Salisbury J; Zacharioudakis G; Vardi A; Hagner PR; Gandhi AK; Bacac M; Claus C; Umana P; Jarrett RF; Klein C; Deutsch A; Ramsay AG
Article: CURRENT RESEARCH IN TRANSLATIONAL MEDICINE. 2023;71(3):103401

Establishment and characterization of a novel breast implant-associated anaplastic large cell lymphoma cell line and PDX model (BIA-XR1) with a unique KRAS mutation.

Xagoraris I; Stathopoulou K; Aulerio RD; He M; Ketscher A; Jatta K; de Flon FH; Barbany G; Rosenquist R; Westerberg LS; Rassidakis GZ
Article: BLOOD ADVANCES. 2023;7(12):2794-2806

BTK and PLCG2 remain unmutated in one-third of patients with CLL relapsing on ibrutinib.

Bonfiglio S; Sutton L-A; Ljungström V; Capasso A; Pandzic T; Weström S; Foroughi-Asl H; Skaftason A; Gellerbring A; Lyander A; Gandini F; Gaidano G; Trentin L; Bonello L; Reda G; Bödör C; Stavroyianni N; Tam CS; Marasca R; Forconi F; Panayiotidis P; Ringshausen I; Jaksic O; Frustaci AM; Iyengar S; Coscia M; Mulligan SP; Ysebaert L; Strugov V; Pavlovsky C; Walewska R; Österborg A; Cortese D; Ranghetti P; Baliakas P; Stamatopoulos K; Scarfò L; Rosenquist R; Ghia P
Article: JCO PRECISION ONCOLOGY. 2023;7:e2300039

Diagnostic Yield From a Nationwide Implementation of Precision Medicine for all Children With Cancer.

Wadensten E; Wessman S; Abel F; Diaz De Ståhl T; Tesi B; Orsmark Pietras C; Arvidsson L; Taylan F; Fransson S; Vogt H; Poluha A; Pradhananga S; Hellberg M; Lagerstedt-Robinson K; Raj Somarajan P; Samuelsson S; Orrsjö S; Maqbool K; Henning K; Strid T; Ek T; Fagman H; Olsson Bontell T; Martinsson T; Puls F; Kogner P; Wirta V; Pronk CJ; Wille J; Rosenquist R; Nistér M; Mertens F; Sabel M; Norén-Nyström U; Grillner P; Nordgren A; Ljungman G; Sandgren J; Gisselsson D; Genomic Medicine Sweden Childhood Cancer Working G
Article: LAKARTIDNINGEN. 2023;120:22139

Precisionsmedicin kräver samverkan och långsiktighet.

Edsjö A; Fioretos T; Rosenquist R
Article: CANCERS. 2023;15(7):1972

Simultaneous Ultra-Sensitive Detection of Structural and Single Nucleotide Variants Using Multiplex Droplet Digital PCR in Liquid Biopsies from Children with Medulloblastoma.

Arthur C; Jylhä C; de Ståhl TD; Shamikh A; Sandgren J; Rosenquist R; Nordenskjöld M; Harila A; Barbany G; Sandvik U; Tham E
Article: LEUKEMIA. 2023;37(2):339-347

Different prognostic impact of recurrent gene mutations in chronic lymphocytic leukemia depending on IGHV gene somatic hypermutation status: a study by ERIC in HARMONY.

Mansouri L; Thorvaldsdottir B; Sutton L-A; Karakatsoulis G; Meggendorfer M; Parker H; Nadeu F; Brieghel C; Laidou S; Moia R; Rossi D; Catherwood M; Kotaskova J; Delgado J; Rodríguez-Vicente AE; Benito R; Rigolin GM; Bonfiglio S; Scarfo L; Mattsson M; Davis Z; Gogia A; Rani L; Baliakas P; Foroughi-Asl H; Jylhä C; Skaftason A; Rapado I; Miras F; Martinez-Lopez J; de la Serna J; Rivas JMH; Thornton P; Larráyoz MJ; Calasanz MJ; Fésüs V; Mátrai Z; Bödör C; Smedby KE; Espinet B; Puiggros A; Gupta R; Bullinger L; Bosch F; Tazón-Vega B; Baran-Marszak F; Oscier D; Nguyen-Khac F; Zenz T; Terol MJ; Cuneo A; Hernández-Sánchez M; Pospisilova S; Mills K; Gaidano G; Niemann CU; Campo E; Strefford JC; Ghia P; Stamatopoulos K; Rosenquist R
Article: FRONTIERS IN ONCOLOGY. 2023;13:1097942

T cell receptor gene repertoire profiles in subgroups of patients with chronic lymphocytic leukemia bearing distinct genomic aberrations.

Vlachonikola E; Pechlivanis N; Karakatsoulis G; Sofou E; Gkoliou G; Jeromin S; Stavroyianni N; Ranghetti P; Scarfo L; Österholm C; Mansouri L; Notopoulou S; Siorenta A; Anagnostopoulos A; Ghia P; Haferlach C; Rosenquist R; Psomopoulos F; Kouvatsi A; Baliakas P; Stamatopoulos K; Chatzidimitriou A
Article: FRONTIERS IN ONCOLOGY. 2023;13:1217712

Feasibility to use whole-genome sequencing as a sole diagnostic method to detect genomic aberrations in pediatric B-cell acute lymphoblastic leukemia.

Rezayee F; Eisfeldt J; Skaftason A; Öfverholm I; Sayyab S; Syvänen AC; Maqbool K; Lilljebjörn H; Johansson B; Olsson-Arvidsson L; Pietras CO; Staffas A; Palmqvist L; Fioretos T; Cavelier L; Fogelstrand L; Nordlund J; Wirta V; Rosenquist R; Barbany G
Article: FRONTIERS IN ONCOLOGY. 2023;13:1176698

Whole-genome informed circulating tumor DNA analysis by multiplex digital PCR for disease monitoring in B-cell lymphomas: a proof-of-concept study.

Haider Z; Wästerlid T; Spångberg LD; Rabbani L; Jylhä C; Thorvaldsdottir B; Skaftason A; Awier HN; Krstic A; Gellerbring A; Lyander A; Hägglund M; Jeggari A; Rassidakis G; Sonnevi K; Sander B; Rosenquist R; Tham E; Smedby KE
Article: JCO PRECISION ONCOLOGY. 2022;6:e2200245

Implementation of Whole-Genome and Transcriptome Sequencing Into Clinical Cancer Care.

Cuppen E; Elemento O; Rosenquist R; Nikic S; IJzerman M; Zaleski ID; Frederix G; Levin L-Å; Mullighan CG; Buettner R; Pugh TJ; Grimmond S; Caldas C; Andre F; Custers I; Campo E; van Snellenberg H; Schuh A; Nakagawa H; von Kalle C; Haferlach T; Fröhling S; Jobanputra V
Article: BLOOD. 2022;140(21):2193-2227

Genomic profiling for clinical decision making in lymphoid neoplasms.

de Leval L; Alizadeh AA; Bergsagel PL; Campo E; Davies A; Dogan A; Fitzgibbon J; Horwitz SM; Melnick AM; Morice WG; Morin RD; Nadel B; Pileri SA; Rosenquist R; Rossi D; Salaverria I; Steidl C; Treon SP; Zelenetz AD; Advani RH; Allen CE; Ansell SM; Chan WC; Cook JR; Cook LB; d'Amore F; Dirnhofer S; Dreyling M; Dunleavy K; Feldman AL; Fend F; Gaulard P; Ghia P; Gribben JG; Hermine O; Hodson DJ; Hsi ED; Inghirami G; Jaffe ES; Karube K; Kataoka K; Klapper W; Kim WS; King RL; Ko YH; LaCasce AS; Lenz G; Martin-Subero JI; Piris MA; Pittaluga S; Pasqualucci L; Quintanilla-Martinez L; Rodig SJ; Rosenwald A; Salles GA; San-Miguel J; Savage KJ; Sehn LH; Semenzato G; Staudt LM; Swerdlow SH; Tam CS; Trotman J; Vose JM; Weigert O; Wilson WH; Winter JN; Wu CJ; Zinzani PL; Zucca E; Bagg A; Scott DW
Article: NATURE COMMUNICATIONS. 2022;13(1):6226

Proteogenomics refines the molecular classification of chronic lymphocytic leukemia.

Herbst SA; Vesterlund M; Helmboldt AJ; Jafari R; Siavelis I; Stahl M; Schitter EC; Liebers N; Brinkmann BJ; Czernilofsky F; Roider T; Bruch P-M; Iskar M; Kittai A; Huang Y; Lu J; Richter S; Mermelekas G; Umer HM; Knoll M; Kolb C; Lenze A; Cao X; Österholm C; Wahnschaffe L; Herling C; Scheinost S; Ganzinger M; Mansouri L; Kriegsmann K; Kriegsmann M; Anders S; Zapatka M; Del Poeta G; Zucchetto A; Bomben R; Gattei V; Dreger P; Woyach J; Herling M; Müller-Tidow C; Rosenquist R; Stilgenbauer S; Zenz T; Huber W; Tausch E; Lehtiö J; Dietrich S
Article: SEMINARS IN CANCER BIOLOGY. 2022;84:170-183

Precision diagnostics in lymphomas - Recent developments and future directions.

Mansouri L; Thorvaldsdottir B; Laidou S; Stamatopoulos K; Rosenquist R
Article: SEMINARS IN CANCER BIOLOGY. 2022;84:242-254

Trailblazing precision medicine in Europe: A joint view by Genomic Medicine Sweden and the Centers for Personalized Medicine, ZPM, in Germany.

Stenzinger A; Edsjö A; Ploeger C; Friedman M; Fröhling S; Wirta V; Seufferlein T; Botling J; Duyster J; Akhras M; Thimme R; Fioretos T; Bitzer M; Cavelier L; Schirmacher P; Malek N; Rosenquist R; GMS working group and ZPM working group
Article: BLOOD. 2022;139(22):3340-3344

Secondary resistance to idelalisib is characterized by upregulation of IGF1R rather than by MAPK/ERK pathway mutations.

Tausch E; Ljungström V; Agathangelidis A; Zapatka M; Scarfò L; Jebaraj BMC; Yosifov DY; Müller A; Munugalavadla V; Degenhardt JD; Ghia P; Rosenquist R; Stilgenbauer S
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2022;197(4):431-441

International validation of the EORTC QLQ-CLL17 questionnaire for assessment of health-related quality of life for patients with chronic lymphocytic leukaemia.

Oerlemans S; Efficace F; Kieffer JM; Kyriakou C; Xochelli A; Levedahl K; Petranovic D; Borges FC; Bredart A; Shamieh O; Gziskevicius L; Lehmann J; Scholz CW; Caocci G; Molica S; Stamatopoulos K; Panteliadou A-K; Papaioannou M; Alrjoob W; Baliakas P; Rosenquist R; Malak S; Miranda A; Cocks K; van de Poll-Franse L; EORTC Quality of Life Group
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2022;108(5):369-378

Identifying patients with chronic lymphocytic leukemia without need of treatment: End of endless watch and wait?

Brieghel C; Galle V; Agius R; da Cunha-Bang C; Andersen MA; Vlummens P; Mattsson M; Rosenquist R; Smedby KE; Herling CD; Bahlo J; Hallek M; Lundgren JD; Offner F; Niemann CU
Article: BLOOD ADVANCES. 2022;6(8):2657-2666

Incidence and time trends of second primary malignancies after non-Hodgkin lymphoma: a Swedish population-based study.

Joelsson J; Wästerlid T; Rosenquist R; Jakobsen LH; El-Galaly TC; Smedby KE; Eloranta S
Article: GENES CHROMOSOMES & CANCER. 2022;61(1):27-36

Transcriptome sequencing of archived lymphoma specimens is feasible and clinically relevant using exome capture technology.

Skaftason A; Qu Y; Abdulla M; Nordlund J; Berglund M; Ednersson SB; Andersson P-O; Enblad G; Amini R-M; Rosenquist R; Mansouri L
Article: FRONTIERS IN MEDICINE. 2022;9:842507

A Study Protocol for Validation and Implementation of Whole-Genome and -Transcriptome Sequencing as a Comprehensive Precision Diagnostic Test in Acute Leukemias.

Berglund E; Barbany G; Orsmark-Pietras C; Fogelstrand L; Abrahamsson J; Golovleva I; Hallböök H; Höglund M; Lazarevic V; Levin L-Å; Nordlund J; Norèn-Nyström U; Palle J; Thangavelu T; Palmqvist L; Wirta V; Cavelier L; Fioretos T; Rosenquist R
Article: FRONTIERS IN ONCOLOGY. 2022;12:899325

Patient-Specific Assays Based on Whole-Genome Sequencing Data to Measure Residual Disease in Children With Acute Lymphoblastic Leukemia: A Proof of Concept Study.

Arthur C; Rezayee F; Mogensen N; Saft L; Rosenquist R; Nordenskjöld M; Harila-Saari A; Tham E; Barbany G
Article: FRONTIERS IN ONCOLOGY. 2022;12:897280

Impact of the Types and Relative Quantities of IGHV Gene Mutations in Predicting Prognosis of Patients With Chronic Lymphocytic Leukemia.

Kaufman M; Yan X-J; Li W; Ghia EM; Langerak AW; Rassenti LZ; Belessi C; Kay NE; Davi F; Byrd JC; Pospisilova S; Brown JR; Catherwood M; Davis Z; Oscier D; Montillo M; Trentin L; Rosenquist R; Ghia P; Barrientos JC; Kolitz JE; Allen SL; Rai KR; Stamatopoulos K; Kipps TJ; Neuberg D; Chiorazzi N
Article: BMJ OPEN. 2021;11(11):e050256

MyPal ADULT study protocol: a randomised clinical trial of the MyPal ePRO-based early palliative care system in adult patients with haematological malignancies.

Scarfò L; Karamanidou C; Doubek M; Garani-Papadatos T; Didi J; Pontikoglou C; Ling J; Payne C; Papadaki HΑ; Rosenquist R; Stavroyianni N; Payne S; Ghia P; Natsiavas P; Maramis C; Stamatopoulos K
Article: BLOOD ADVANCES. 2021;5(13):2788-2792

RPS15 mutations rewire RNA translation in chronic lymphocytic leukemia.

Ntoufa S; Gerousi M; Laidou S; Psomopoulos F; Tsiolas G; Moysiadis T; Papakonstantinou N; Mansouri L; Anagnostopoulos A; Stavrogianni N; Pospisilova S; Plevova K; Makris AM; Rosenquist R; Stamatopoulos K
Article: HEMATOLOGICAL ONCOLOGY. 2021;39 Suppl 1:73-77

Molecular diagnostics and reporting in lymphoid malignancies: Current status and beyond.

Rosenquist R
Article: LAKARTIDNINGEN. 2021;118:21023

[Genomic Medicine Sweden - a national initiative for the broad introduction of precision medicine in Swedish healthcare].

Edsjö A; Friedman M; Rosenquist R
Article: LAKARTIDNINGEN. 2021;118:20186

[Precision diagnostics and therapy in hematological malignancies].

Hellström Lindberg E; Cavelier L; Cammenga J; Andersson P-O; Fioretos T; Rosenquist R
Article: BLOOD. 2021;137(14):1895-1904

Higher-order immunoglobulin repertoire restrictions in CLL: the illustrative case of stereotyped subsets 2 and 169.

Gemenetzi K; Psomopoulos F; Carriles AA; Gounari M; Minici C; Plevova K; Sutton L-A; Tsagiopoulou M; Baliakas P; Pasentsis K; Anagnostopoulos A; Sandaltzopoulos R; Rosenquist R; Davi F; Pospisilova S; Ghia P; Stamatopoulos K; Degano M; Chatzidimitriou A
Article: BLOOD. 2021;137(10):1365-1376

Higher-order connections between stereotyped subsets: implications for improved patient classification in CLL.

Agathangelidis A; Chatzidimitriou A; Gemenetzi K; Giudicelli V; Karypidou M; Plevova K; Davis Z; Yan X-J; Jeromin S; Schneider C; Pedersen LB; Tschumper RC; Sutton L-A; Baliakas P; Scarfò L; van Gastel EJ; Armand M; Tausch E; Biderman B; Baer C; Bagnara D; Navarro A; Langlois de Septenville A; Guido V; Mitterbauer-Hohendanner G; Dimovski A; Brieghel C; Lawless S; Meggendorfer M; Brazdilova K; Ritgen M; Facco M; Tresoldi C; Visentin A; Patriarca A; Catherwood M; Bonello L; Sudarikov A; Vanura K; Roumelioti M; Skuhrova Francova H; Moysiadis T; Veronese S; Giannopoulos K; Mansouri L; Karan-Djurasevic T; Sandaltzopoulos R; Bödör C; Fais F; Kater AP; Panovska I; Rossi D; Alshemmari S; Panagiotidis P; Costeas P; Espinet B; Antic D; Foroni L; Montillo M; Trentin L; Stavroyianni N; Gaidano G; Francia di Celle P; Niemann C; Campo E; Anagnostopoulos A; Pott C; Fischer K; Hallek M; Oscier D; Stilgenbauer S; Haferlach C; Jelinek D; Chiorazzi N; Pospisilova S; Lefranc M-P; Kossida S; Langerak AW; Belessi C; Davi F; Rosenquist R; Ghia P; Stamatopoulos K
Article: HAEMATOLOGICA. 2021;106(3):682-691

Comparative analysis of targeted next-generation sequencing panels for the detection of gene mutations in chronic lymphocytic leukemia: an ERIC multi-center study.

Sutton L-A; Ljungström V; Enjuanes A; Cortese D; Skaftason A; Tausch E; Stano Kozubik K; Nadeu F; Armand M; Malcikova J; Pandzic T; Forster J; Davis Z; Oscier D; Rossi D; Ghia P; Strefford JC; Pospisilova S; Stilgenbauer S; Davi F; Campo E; Stamatopoulos K; Rosenquist R; On Behalf Of The European Research Initiative On C
Article: HAEMATOLOGICA. 2021;106(1):87-97

Genomic arrays identify high-risk chronic lymphocytic leukemia with genomic complexity: a multi-center study.

Leeksma AC; Baliakas P; Moysiadis T; Puiggros A; Plevova K; Van der Kevie-Kersemaekers A-M; Posthuma H; Rodriguez-Vicente AE; Tran AN; Barbany G; Mansouri L; Gunnarsson R; Parker H; Van den Berg E; Bellido M; Davis Z; Wall M; Scarpelli I; Österborg A; Hansson L; Jarosova M; Ghia P; Poddighe P; Espinet B; Pospisilova S; Tam C; Ysebaert L; Nguyen-Khac F; Oscier D; Haferlach C; Schoumans J; Stevens-Kroef M; Eldering E; Stamatopoulos K; Rosenquist R; Strefford JC; Mellink C; Kater AP
Article: FRONTIERS IN ONCOLOGY. 2021;11:740083

Consistent B Cell Receptor Immunoglobulin Features Between Siblings in Familial Chronic Lymphocytic Leukemia.

Kolijn PM; Muggen AF; Ljungström V; Agathangelidis A; Wolvers-Tettero ILM; Beverloo HB; Pál K; Hengeveld PJ; Darzentas N; Hendriks RW; van Dongen JJM; Rosenquist R; Langerak AW
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2020;105(6):779-785

Concordance in survival among first-degree relatives diagnosed with indolent lymphoid malignancies including chronic lymphocytic leukemia.

Baecklund F; Ekberg S; Rosenquist R; Askling J; Eloranta S; Smedby KE
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2020;191(3):426-432

Risk-adapted bendamustine + rituximab is a tolerable treatment alternative for elderly patients with chronic lymphocytic leukaemia: a regional real-world report on 141 consecutive Swedish patients.

Mattsson A; Sylvan SE; Asklid A; Wiggh J; Winqvist M; Lundin J; Mansouri L; Rosenquist R; Johansson H; Österborg A; Hansson L
Article: HAEMATOLOGICA. 2020;105(11):2598-2607

Prognostic impact of prevalent chronic lymphocytic leukemia stereotyped subsets: analysis within prospective clinical trials of the German CLL Study Group (GCLLSG).

Jaramillo S; Agathangelidis A; Schneider C; Bahlo J; Robrecht S; Tausch E; Bloehdorn J; Hoechstetter M; Fischer K; Eichhorst B; Goede V; Hallek M; Döhner H; Rosenquist R; Ghia P; Stamatopoulos K; Stilgenbauer S
Article: LEUKEMIA. 2020;34(10):2545-2551

Immunoglobulin gene analysis in chronic lymphocytic leukemia in the era of next generation sequencing.

Davi F; Langerak AW; de Septenville AL; Kolijn PM; Hengeveld PJ; Chatzidimitriou A; Bonfiglio S; Sutton L-A; Rosenquist R; Ghia P; Stamatopoulos K; ERIC, the European Research Initiative on CLL, and
Article: BLOOD. 2020;135(21):1859-1869

International prognostic score for asymptomatic early-stage chronic lymphocytic leukemia.

Condoluci A; Terzi di Bergamo L; Langerbeins P; Hoechstetter MA; Herling CD; De Paoli L; Delgado J; Rabe KG; Gentile M; Doubek M; Mauro FR; Chiodin G; Mattsson M; Bahlo J; Cutrona G; Kotaskova J; Deambrogi C; Smedby KE; Spina V; Bruscaggin A; Wu W; Moia R; Bianchi E; Gerber B; Zucca E; Gillessen S; Ghielmini M; Cavalli F; Stussi G; Hess MA; Baumann TS; Neri A; Ferrarini M; Rosenquist R; Forconi F; Foà R; Pospisilova S; Morabito F; Stilgenbauer S; Döhner H; Parikh SA; Wierda WG; Montserrat E; Gaidano G; Hallek M; Rossi D
Article: CLINICAL CANCER RESEARCH. 2020;26(6):1507-1515

The Number of Signaling Pathways Altered by Driver Mutations in Chronic Lymphocytic Leukemia Impacts Disease Outcome.

Brieghel C; da Cunha-Bang C; Yde CW; Schmidt AY; Kinalis S; Nadeu F; Andersen MA; Jacobsen LO; Andersen MK; Pedersen LB; Delgado J; Baumann T; Mattsson M; Mansouri L; Rosenquist R; Campo E; Nielsen FC; Niemann CU
Article: AMERICAN JOURNAL OF HEMATOLOGY. 2020;95(1):57-67

Cell-of-origin determined by both gene expression profiling and immunohistochemistry is the strongest predictor of survival in patients with diffuse large B-cell lymphoma.

Abdulla M; Hollander P; Pandzic T; Mansouri L; Ednersson SB; Andersson P-O; Hultdin M; Fors M; Erlanson M; Degerman S; Petersen HM; Asmar F; Grønbaek K; Enblad G; Cavelier L; Rosenquist R; Amini R-M
Article: CLINICAL EPIGENETICS. 2019;11(1):177

DNA methylation profiles in chronic lymphocytic leukemia patients treated with chemoimmunotherapy.

Tsagiopoulou M; Papakonstantinou N; Moysiadis T; Mansouri L; Ljungström V; Duran-Ferrer M; Malousi A; Queirós AC; Plevova K; Bhoi S; Kollia P; Oscier D; Anagnostopoulos A; Trentin L; Ritgen M; Pospisilova S; Stavroyianni N; Ghia P; Martin-Subero JI; Pott C; Rosenquist R; Stamatopoulos K
Article: EPIGENETICS. 2019;14(11):1125-1140

EZH2 upregulates the PI3K/AKT pathway through IGF1R and MYC in clinically aggressive chronic lymphocytic leukaemia.

Kosalai ST; Morsy MHA; Papakonstantinou N; Mansouri L; Stavroyianni N; Kanduri C; Stamatopoulos K; Rosenquist R; Kanduri M
Article: LEUKEMIA. 2019;33(10):2416-2428

Inhibition of SYK or BTK augments venetoclax sensitivity in SHP1-negative/BCL-2-positive diffuse large B-cell lymphoma.

Sasi BK; Martines C; Xerxa E; Porro F; Kalkan H; Fazio R; Turkalj S; Bojnik E; Pyrzynska B; Stachura J; Zerrouqi A; Bobrowicz M; Winiarska M; Priebe V; Bertoni F; Mansouri L; Rosenquist R; Efremov DG
Article: BLOOD ADVANCES. 2019;3(16):2474-2481

Clinical significance of DNA methylation in chronic lymphocytic leukemia patients: results from 3 UK clinical trials.

Wojdacz TK; Amarasinghe HE; Kadalayil L; Beattie A; Forster J; Blakemore SJ; Parker H; Bryant D; Larrayoz M; Clifford R; Robbe P; Davis ZA; Else M; Howard DR; Stamatopoulos B; Steele AJ; Rosenquist R; Collins A; Pettitt AR; Hillmen P; Plass C; Schuh A; Catovsky D; Oscier DG; Rose-Zerilli MJJ; Oakes CC; Strefford JC
Article: BLOOD ADVANCES. 2019;3(12):1891-1896

Inhibition of EZH2 and immune signaling exerts synergistic antitumor effects in chronic lymphocytic leukemia.

Chartomatsidou E; Ntoufa S; Kotta K; Rovida A; Akritidou MA; Belloni D; Ferrero E; Trangas T; Stavroyianni N; Anagnostopoulos A; Rosenquist R; Ghia P; Papakonstantinou N; Stamatopoulos K
Article: SCIENCE TRANSLATIONAL MEDICINE. 2019;11(497):eaav5599

Targetable genetic alterations of TCF4 (E2-2) drive immunoglobulin expression in diffuse large B cell lymphoma.

Jain N; Hartert K; Tadros S; Fiskus W; Havranek O; Ma MCJ; Bouska A; Heavican T; Kumar D; Deng Q; Moore D; Pak C; Liu CL; Gentles AJ; Hartmann E; Kridel R; Smedby KE; Juliusson G; Rosenquist R; Gascoyne RD; Rosenwald A; Giancotti F; Neelapu SS; Westin J; Vose JM; Lunning MA; Greiner T; Rodig S; Iqbal J; Alizadeh AA; Davis RE; Bhalla K; Green MR
Article: INTERNATIONAL JOURNAL OF CANCER. 2019;144(11):2695-2706

Integrated epigenomic and transcriptomic analysis reveals TP63 as a novel player in clinically aggressive chronic lymphocytic leukemia.

Papakonstantinou N; Ntoufa S; Tsagiopoulou M; Moysiadis T; Bhoi S; Malousi A; Psomopoulos F; Mansouri L; Laidou S; Papazoglou D; Gounari M; Pasentsis K; Plevova K; Kuci-Emruli V; Duran-Ferrer M; Davis Z; Ek S; Rossi D; Gaidano G; Ritgen M; Oscier D; Stavroyianni N; Pospisilova S; Davi F; Ghia P; Hadzidimitriou A; Belessi C; Martin-Subero JI; Pott C; Rosenquist R; Stamatopoulos K
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2019;185(4):708-712

Expression of GNAZ, encoding the Gαz protein, predicts survival in mantle cell lymphoma.

Mundt F; Merrien M; Nygren L; Sutton LA; Christensson B; Wahlin BE; Rosenquist R; Sander B; Wasik AM
Article: JOURNAL OF PATHOLOGY. 2019;247(4):416-421

Disease-biased and shared characteristics of the immunoglobulin gene repertoires in marginal zone B cell lymphoproliferations.

Xochelli A; Bikos V; Polychronidou E; Galigalidou C; Agathangelidis A; Charlotte F; Moschonas P; Davis Z; Colombo M; Roumelioti M; Sutton L-A; Groenen P; van den Brand M; Boudjoghra M; Algara P; Traverse-Glehen A; Ferrer A; Stalika E; Karypidou M; Kanellis G; Kalpadakis C; Mollejo M; Pangalis G; Vlamos P; Amini R-M; Pospisilova S; Gonzalez D; Ponzoni M; Anagnostopoulos A; Giudicelli V; Lefranc M-P; Espinet B; Panagiotidis P; Piris MA; Du M-Q; Rosenquist R; Papadaki T; Belessi C; Ferrarini M; Oscier D; Tzovaras D; Ghia P; Davi F; Hadzidimitriou A; Stamatopoulos K
Article: BLOOD ADVANCES. 2019;3(3):384-396

Genome-wide promoter methylation of hairy cell leukemia.

Arribas AJ; Rinaldi A; Chiodin G; Kwee I; Mensah AA; Cascione L; Rossi D; Kanduri M; Rosenquist R; Zucca E; Johnson PW; Gaidano G; Oakes CC; Bertoni F; Forconi F
Article: HAEMATOLOGICA. 2019;104(2):360-369

Tailored approaches grounded on immunogenetic features for refined prognostication in chronic lymphocytic leukemia.

Baliakas P; Moysiadis T; Hadzidimitriou A; Xochelli A; Jeromin S; Agathangelidis A; Mattsson M; Sutton L-A; Minga E; Scarfò L; Rossi D; Davis Z; Villamor N; Parker H; Kotaskova J; Stalika E; Plevova K; Mansouri L; Cortese D; Navarro A; Delgado J; Larrayoz M; Young E; Anagnostopoulos A; Smedby KE; Juliusson G; Sheehy O; Catherwood M; Strefford JC; Stavroyianni N; Belessi C; Pospisilova S; Oscier D; Gaidano G; Campo E; Haferlach C; Ghia P; Rosenquist R; Stamatopoulos K; European Research Initiative on CLL (ERIC)
Article: METHODS IN MOLECULAR BIOLOGY. 2019;1881:51-62

Immunoglobulin Gene Analysis in Chronic Lymphocytic Leukemia.

Agathangelidis A; Rosenquist R; Davi F; Ghia P; Belessi C; Hadzidimitriou A; Stamatopoulos K
Article: BLOOD CANCER JOURNAL. 2018;9(1):1

Genetic correlation between multiple myeloma and chronic lymphocytic leukaemia provides evidence for shared aetiology.

Went M; Sud A; Speedy H; Sunter NJ; Försti A; Law PJ; Johnson DC; Mirabella F; Holroyd A; Li N; Orlando G; Weinhold N; van Duin M; Chen B; Mitchell JS; Mansouri L; Juliusson G; Smedby KE; Jayne S; Majid A; Dearden C; Allsup DJ; Bailey JR; Pratt G; Pepper C; Fegan C; Rosenquist R; Kuiper R; Stephens OW; Bertsch U; Broderick P; Einsele H; Gregory WM; Hillengass J; Hoffmann P; Jackson GH; Jöckel K-H; Nickel J; Nöthen MM; da Silva Filho MI; Thomsen H; Walker BA; Broyl A; Davies FE; Hansson M; Goldschmidt H; Dyer MJS; Kaiser M; Sonneveld P; Morgan GJ; Hemminki K; Nilsson B; Catovsky D; Allan JM; Houlston RS
Article: JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. 2018;(141)

Immunoglobulin Gene Sequence Analysis In Chronic Lymphocytic Leukemia: From Patient Material To Sequence Interpretation.

Agathangelidis A; Sutton LA; Hadzidimitriou A; Tresoldi C; Langerak AW; Belessi C; Davi F; Rosenquist R; Stamatopoulos K; Ghia P
Article: BMC BIOINFORMATICS. 2018;19(Suppl 14):414

Automated shape-based clustering of 3D immunoglobulin protein structures in chronic lymphocytic leukemia.

Polychronidou E; Kalamaras I; Agathangelidis A; Sutton L-A; Yan X-J; Bikos V; Vardi A; Mochament K; Chiorazzi N; Belessi C; Rosenquist R; Ghia P; Stamatopoulos K; Vlamos P; Chailyan A; Overby N; Marcatili P; Hatzidimitriou A; Tzovaras D
Article: SEMINARS IN CANCER BIOLOGY. 2018;51:1-11

Epigenetic deregulation in chronic lymphocytic leukemia: Clinical and biological impact.

Mansouri L; Wierzbinska JA; Plass C; Rosenquist R
Article: ONCOTARGET. 2018;9(40):26019-26031

A novel ex vivo high-throughput assay reveals antiproliferative effects of idelalisib and ibrutinib in chronic lymphocytic leukemia.

Primo D; Scarfò L; Xochelli A; Mattsson M; Ranghetti P; Espinosa AB; Robles A; Gorrochategui J; Martínez-López J; de la Serna J; González M; Gil AC; Anguita E; Iraheta S; Munugalavadla V; Quéva C; Tannheimer S; Rosenquist R; Stamatopoulos K; Ballesteros J; Ghia P
Article: HAEMATOLOGICA. 2018;103(5):865-873

Highly similar genomic landscapes in monoclonal B-cell lymphocytosis and ultra-stable chronic lymphocytic leukemia with low frequency of driver mutations.

Agathangelidis A; Ljungström V; Scarfò L; Fazi C; Gounari M; Pandzic T; Sutton L-A; Stamatopoulos K; Tonon G; Rosenquist R; Ghia P
Article: BLOOD ADVANCES. 2018;2(6):621-625

Clinical and functional impact of recurrent S1PR1 mutations in mantle cell lymphoma.

Wasik AM; Wu C; Mansouri L; Rosenquist R; Pan-Hammarström Q; Sander B
Article: ACTA ONCOLOGICA. 2018;57(2):187-194

U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden.

Glimelius B; Melin B; Enblad G; Alafuzoff I; Beskow A; Ahlström H; Bill-Axelson A; Birgisson H; Björ O; Edqvist P-H; Hansson T; Helleday T; Hellman P; Henriksson K; Hesselager G; Hultdin M; Häggman M; Höglund M; Jonsson H; Larsson C; Lindman H; Ljuslinder I; Mindus S; Nygren P; Pontén F; Riklund K; Rosenquist R; Sandin F; Schwenk JM; Stenling R; Stålberg K; Stålberg P; Sundström C; Thellenberg Karlsson C; Westermark B; Bergh A; Claesson-Welsh L; Palmqvist R; Sjöblom T
Article: JOURNAL OF CLINICAL INVESTIGATION. 2018;128(1):427-445

Drug-perturbation-based stratification of blood cancer.

Dietrich S; Oleś M; Lu J; Sellner L; Anders S; Velten B; Wu B; Hüllein J; da Silva Liberio M; Walther T; Wagner L; Rabe S; Ghidelli-Disse S; Bantscheff M; Oleś AK; Słabicki M; Mock A; Oakes CC; Wang S; Oppermann S; Lukas M; Kim V; Sill M; Benner A; Jauch A; Sutton LA; Young E; Rosenquist R; Liu X; Jethwa A; Lee KS; Lewis J; Putzker K; Lutz C; Rossi D; Mokhir A; Oellerich T; Zirlik K; Herling M; Nguyen-Khac F; Plass C; Andersson E; Mustjoki S; von Kalle C; Ho AD; Hensel M; Dürig J; Ringshausen I; Zapatka M; Huber W; Zenz T
Article: CYTOMETRY PART B-CLINICAL CYTOMETRY. 2018;94(1):121-128

Reproducible diagnosis of chronic lymphocytic leukemia by flow cytometry: An European Research Initiative on CLL (ERIC) & European Society for Clinical Cell Analysis (ESCCA) Harmonisation project.

Rawstron AC; Kreuzer K-A; Soosapilla A; Spacek M; Stehlikova O; Gambell P; McIver-Brown N; Villamor N; Psarra K; Arroz M; Milani R; de la Serna J; Cedena MT; Jaksic O; Nomdedeu J; Moreno C; Rigolin GM; Cuneo A; Johansen P; Johnsen HE; Rosenquist R; Niemann CU; Kern W; Westerman D; Trneny M; Mulligan S; Doubek M; Pospisilova S; Hillmen P; Oscier D; Hallek M; Ghia P; Montserrat E
Article: CLINICAL CANCER RESEARCH. 2017;23(17):5292-5301

Chronic Lymphocytic Leukemia with Mutated IGHV4-34 Receptors: Shared and Distinct Immunogenetic Features and Clinical Outcomes.

Xochelli A; Baliakas P; Kavakiotis I; Agathangelidis A; Sutton L-A; Minga E; Ntoufa S; Tausch E; Yan X-J; Shanafelt T; Plevova K; Boudjogra M; Rossi D; Davis Z; Navarro A; Sandberg Y; Vojdeman FJ; Scarfo L; Stavroyianni N; Sudarikov A; Veronese S; Tzenou T; Karan-Djurasevic T; Catherwood M; Kienle D; Chatzouli M; Facco M; Bahlo J; Pott C; Pedersen LB; Mansouri L; Smedby KE; Chu CC; Giudicelli V; Lefranc M-P; Panagiotidis P; Juliusson G; Anagnostopoulos A; Vlahavas I; Antic D; Trentin L; Montillo M; Niemann C; Döhner H; Langerak AW; Pospisilova S; Hallek M; Campo E; Chiorazzi N; Maglaveras N; Oscier D; Gaidano G; Jelinek DF; Stilgenbauer S; Chouvarda I; Darzentas N; Belessi C; Davi F; Hadzidimitriou A; Rosenquist R; Ghia P; Stamatopoulos K
Article: LEUKEMIA. 2017;31(7):1547-1554

EGR2 mutations define a new clinically aggressive subgroup of chronic lymphocytic leukemia.

Young E; Noerenberg D; Mansouri L; Ljungström V; Frick M; Sutton L-A; Blakemore SJ; Galan-Sousa J; Plevova K; Baliakas P; Rossi D; Clifford R; Roos-Weil D; Navrkalova V; Dörken B; Schmitt CA; Smedby KE; Juliusson G; Giacopelli B; Blachly JS; Belessi C; Panagiotidis P; Chiorazzi N; Davi F; Langerak AW; Oscier D; Schuh A; Gaidano G; Ghia P; Xu W; Fan L; Bernard OA; Nguyen-Khac F; Rassenti L; Li J; Kipps TJ; Stamatopoulos K; Pospisilova S; Zenz T; Oakes CC; Strefford JC; Rosenquist R; Damm F
Article: AMERICAN JOURNAL OF PATHOLOGY. 2017;187(7):1454-1458

Numerous Ontogenetic Roads to Mantle Cell Lymphoma: Immunogenetic and Immunohistochemical Evidence.

Pouliou E; Xochelli A; Kanellis G; Stalika E; Sutton L-A; Navarro A; Agathangelidis A; Dimosthenous K; Anagnostopoulos A; Patsouris E; Korkolopoulou P; Sundstrom C; Ghia P; Ponzoni M; Sander B; Campo E; Rosenquist R; Hadzidimitriou A; Stamatopoulos K; Papadaki T
Article: AMERICAN JOURNAL OF EPIDEMIOLOGY. 2017;185(8):681-687

Possible Interaction Between Cigarette Smoking and HLA-DRB1 Variation in the Risk of Follicular Lymphoma.

Baecklund F; Foo J-N; Askling J; Eloranta S; Glimelius I; Liu J; Hjalgrim H; Rosenquist R; Padyukov L; Smedby KE
Article: SCIENTIFIC REPORTS. 2017;7(1):623

Flow Cytometric Measurement of Blood Cells with BCR-ABL1 Fusion Protein in Chronic Myeloid Leukemia.

Löf L; Arngården L; Olsson-Strömberg U; Siart B; Jansson M; Dahlin JS; Thörn I; Christiansson L; Hermansson M; Larsson A; Ahlstrand E; Wålinder G; Söderberg O; Rosenquist R; Landegren U; Kamali-Moghaddam M
Article: HAEMATOLOGICA. 2017;102(3):562-572

T cells in chronic lymphocytic leukemia display dysregulated expression of immune checkpoints and activation markers.

Palma M; Gentilcore G; Heimersson K; Mozaffari F; Näsman-Glaser B; Young E; Rosenquist R; Hansson L; Österborg A; Mellstedt H
Article: NATURE COMMUNICATIONS. 2017;8:14175

Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.

Law PJ; Berndt SI; Speedy HE; Camp NJ; Sava GP; Skibola CF; Holroyd A; Joseph V; Sunter NJ; Nieters A; Bea S; Monnereau A; Martin-Garcia D; Goldin LR; Clot G; Teras LR; Quintela I; Birmann BM; Jayne S; Cozen W; Majid A; Smedby KE; Lan Q; Dearden C; Brooks-Wilson AR; Hall AG; Purdue MP; Mainou-Fowler T; Vajdic CM; Jackson GH; Cocco P; Marr H; Zhang Y; Zheng T; Giles GG; Lawrence C; Call TG; Liebow M; Melbye M; Glimelius B; Mansouri L; Glenn M; Curtin K; Diver WR; Link BK; Conde L; Bracci PM; Holly EA; Jackson RD; Tinker LF; Benavente Y; Boffetta P; Brennan P; Maynadie M; McKay J; Albanes D; Weinstein S; Wang Z; Caporaso NE; Morton LM; Severson RK; Riboli E; Vineis P; Vermeulen RCH; Southey MC; Milne RL; Clavel J; Topka S; Spinelli JJ; Kraft P; Ennas MG; Summerfield G; Ferri GM; Harris RJ; Miligi L; Pettitt AR; North KE; Allsup DJ; Fraumeni JF; Bailey JR; Offit K; Pratt G; Hjalgrim H; Pepper C; Chanock SJ; Fegan C; Rosenquist R; de Sanjose S; Carracedo A; Dyer MJS; Catovsky D; Campo E; Cerhan JR; Allan JM; Rothman N; Houlston R; Slager S
Article: CLINICAL CANCER RESEARCH. 2016;22(24):6217-6227

Transposon Mutagenesis Reveals Fludarabine Resistance Mechanisms in Chronic Lymphocytic Leukemia.

Pandzic T; Larsson J; He L; Kundu S; Ban K; Akhtar-Ali M; Hellström AR; Schuh A; Clifford R; Blakemore SJ; Strefford JC; Baumann T; Lopez-Guillermo A; Campo E; Ljungström V; Mansouri L; Rosenquist R; Sjöblom T; Hellström M
Article: BLOOD. 2016;128(23):2666-2670

Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma.

Mansouri L; Noerenberg D; Young E; Mylonas E; Abdulla M; Frick M; Asmar F; Ljungström V; Schneider M; Yoshida K; Skaftason A; Pandzic T; Gonzalez B; Tasidou A; Waldhueter N; Rivas-Delgado A; Angelopoulou M; Ziepert M; Arends CM; Couronné L; Lenze D; Baldus CD; Bastard C; Okosun J; Fitzgibbon J; Dörken B; Drexler HG; Roos-Weil D; Schmitt CA; Munch-Petersen HD; Zenz T; Hansmann M-L; Strefford JC; Enblad G; Bernard OA; Ralfkiaer E; Erlanson M; Korkolopoulou P; Hultdin M; Papadaki T; Grønbæk K; Lopez-Guillermo A; Ogawa S; Küppers R; Stamatopoulos K; Stavroyianni N; Kanellis G; Rosenwald A; Campo E; Amini R-M; Ott G; Vassilakopoulos TP; Hummel M; Rosenquist R; Damm F
Article: LEUKEMIA. 2016;30(11):2179-2186

Genomic disruption of the histone methyltransferase SETD2 in chronic lymphocytic leukaemia.

Parker H; Rose-Zerilli MJJ; Larrayoz M; Clifford R; Edelmann J; Blakemore S; Gibson J; Wang J; Ljungström V; Wojdacz TK; Chaplin T; Roghanian A; Davis Z; Parker A; Tausch E; Ntoufa S; Ramos S; Robbe P; Alsolami R; Steele AJ; Packham G; Rodríguez-Vicente AE; Brown L; McNicholl F; Forconi F; Pettitt A; Hillmen P; Dyer M; Cragg MS; Chelala C; Oakes CC; Rosenquist R; Stamatopoulos K; Stilgenbauer S; Knight S; Schuh A; Oscier DG; Strefford JC
Article: NATURE COMMUNICATIONS. 2016;7:13182

Massive and parallel expression profiling using microarrayed single-cell sequencing.

Vickovic S; Ståhl PL; Salmén F; Giatrellis S; Westholm JO; Mollbrink A; Navarro JF; Custodio J; Bienko M; Sutton L-A; Rosenquist R; Frisén J; Lundeberg J
Article: HAEMATOLOGICA. 2016;101(8):959-967

Different spectra of recurrent gene mutations in subsets of chronic lymphocytic leukemia harboring stereotyped B-cell receptors.

Sutton L-A; Young E; Baliakas P; Hadzidimitriou A; Moysiadis T; Plevova K; Rossi D; Kminkova J; Stalika E; Pedersen LB; Malcikova J; Agathangelidis A; Davis Z; Mansouri L; Scarfò L; Boudjoghra M; Navarro A; Muggen AF; Yan X-J; Nguyen-Khac F; Larrayoz M; Panagiotidis P; Chiorazzi N; Niemann CU; Belessi C; Campo E; Strefford JC; Langerak AW; Oscier D; Gaidano G; Pospisilova S; Davi F; Ghia P; Stamatopoulos K; Rosenquist R; ERIC, the European Research Initiative on CLL
Article: ONCOTARGET. 2016;7(25):38180-38190

Genetic heterogeneity in primary and relapsed mantle cell lymphomas: Impact of recurrent CARD11 mutations.

Wu C; de Miranda NF; Chen L; Wasik AM; Mansouri L; Jurczak W; Galazka K; Dlugosz-Danecka M; Machaczka M; Zhang H; Peng R; Morin RD; Rosenquist R; Sander B; Pan-Hammarström Q
Article: ONCOTARGET. 2016;7(24):35946-35959

The histone methyltransferase EZH2 as a novel prosurvival factor in clinically aggressive chronic lymphocytic leukemia.

Papakonstantinou N; Ntoufa S; Chartomatsidou E; Kotta K; Agathangelidis A; Giassafaki L; Karamanli T; Bele P; Moysiadis T; Baliakas P; Sutton LA; Stavroyianni N; Anagnostopoulos A; Makris AM; Ghia P; Rosenquist R; Stamatopoulos K
Article: EPIGENETICS. 2016;11(6):449-455

Prognostic impact of epigenetic classification in chronic lymphocytic leukemia: The case of subset #2.

Bhoi S; Ljungström V; Baliakas P; Mattsson M; Smedby KE; Juliusson G; Rosenquist R; Mansouri L
Article: EPIGENETICS. 2016;11(5):335-343

Epigenetic silencing of miR-26A1 in chronic lymphocytic leukemia and mantle cell lymphoma: Impact on EZH2 expression.

Kopparapu PK; Bhoi S; Mansouri L; Arabanian LS; Plevova K; Pospisilova S; Wasik AM; Croci GA; Sander B; Paulli M; Rosenquist R; Kanduri M
Article: CLINICAL CANCER RESEARCH. 2016;22(8):2032-2040

An Immunogenetic Signature of Ongoing Antigen Interactions in Splenic Marginal Zone Lymphoma Expressing IGHV1-2*04 Receptors.

Bikos V; Karypidou M; Stalika E; Baliakas P; Xochelli A; Sutton L-A; Papadopoulos G; Agathangelidis A; Papadopoulou E; Davis Z; Algara P; Kanellis G; Traverse-Glehen A; Mollejo M; Anagnostopoulos A; Ponzoni M; Gonzalez D; Pospisilova S; Matutes E; Piris MA; Papadaki T; Ghia P; Rosenquist R; Oscier D; Darzentas N; Tzovaras D; Belessi C; Hadzidimitriou A; Stamatopoulos K
Article: BLOOD. 2016;127(8):1007-1016

Whole-exome sequencing in relapsing chronic lymphocytic leukemia: clinical impact of recurrent RPS15 mutations.

Ljungström V; Cortese D; Young E; Pandzic T; Mansouri L; Plevova K; Ntoufa S; Baliakas P; Clifford R; Sutton L-A; Blakemore SJ; Stavroyianni N; Agathangelidis A; Rossi D; Höglund M; Kotaskova J; Juliusson G; Belessi C; Chiorazzi N; Panagiotidis P; Langerak AW; Smedby KE; Oscier D; Gaidano G; Schuh A; Davi F; Pott C; Strefford JC; Trentin L; Pospisilova S; Ghia P; Stamatopoulos K; Sjöblom T; Rosenquist R
Article: CLINICAL CANCER RESEARCH. 2016;22(1):167-174

Antigen Selection Shapes the T-cell Repertoire in Chronic Lymphocytic Leukemia.

Vardi A; Agathangelidis A; Stalika E; Karypidou M; Siorenta A; Anagnostopoulos A; Rosenquist R; Hadzidimitriou A; Ghia P; Sutton L-A; Stamatopoulos K
Journal article: SCIENCE. 2015;350(6266):1397

The impact of new technologies on clinical decision-making in health care

Rosenquist Brandell R; Kallioniemi O; Wedell A
Article: CLINICAL CANCER RESEARCH. 2015;21(18):4174-4183

Genetics and Prognostication in Splenic Marginal Zone Lymphoma: Revelations from Deep Sequencing.

Parry M; Rose-Zerilli MJ; Ljungström V; Gibson J; Wang J; Walewska R; Parker H; Parker A; Davis Z; Gardiner A; McIver-Brown N; Kalpadakis C; Xochelli A; Anagnostopoulos A; Fazi C; de Castro DG; Dearden C; Pratt G; Rosenquist R; Ashton-Key M; Forconi F; Collins A; Ghia P; Matutes E; Pangalis G; Stamatopoulos K; Oscier D; Strefford JC
Article: BLOOD. 2015;126(2):233-241

SF3B1 mutation identifies a distinct subset of myelodysplastic syndrome with ring sideroblasts.

Malcovati L; Karimi M; Papaemmanuil E; Ambaglio I; Jädersten M; Jansson M; Elena C; Gallì A; Walldin G; Della Porta MG; Raaschou-Jensen K; Travaglino E; Kallenbach K; Pietra D; Ljungström V; Conte S; Boveri E; Invernizzi R; Rosenquist R; Campbell PJ; Cazzola M; Hellström Lindberg E
Article: AMERICAN JOURNAL OF PATHOLOGY. 2015;185(6):1740-1748

Molecular evidence for antigen drive in the natural history of mantle cell lymphoma.

Xochelli A; Sutton L-A; Agathangelidis A; Stalika E; Karypidou M; Marantidou F; Lopez AN; Papadopoulos G; Supikova J; Groenen P; Boudjogra M; Sundstrom C; Ponzoni M; Francova HS; Anagnostopoulos A; Pospisilova S; Papadaki T; Tzovaras D; Ghia P; Pott C; Davi F; Campo E; Rosenquist R; Hadzidimitriou A; Belessi C; Stamatopoulos K
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2015;212(6):833-843

Functional loss of IκBε leads to NF-κB deregulation in aggressive chronic lymphocytic leukemia.

Mansouri L; Sutton L-A; Ljungström V; Bondza S; Arngården L; Bhoi S; Larsson J; Cortese D; Kalushkova A; Plevova K; Young E; Gunnarsson R; Falk-Sörqvist E; Lönn P; Muggen AF; Yan X-J; Sander B; Enblad G; Smedby KE; Juliusson G; Belessi C; Rung J; Chiorazzi N; Strefford JC; Langerak AW; Pospisilova S; Davi F; Hellström M; Jernberg-Wiklund H; Ghia P; Söderberg O; Stamatopoulos K; Nilsson M; Rosenquist R
Article: BREAST CANCER RESEARCH. 2015;17(1):61

An original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriers.

Blein S; Bardel C; Danjean V; McGuffog L; Healey S; Barrowdale D; Lee A; Dennis J; Kuchenbaecker KB; Soucy P; Terry MB; Chung WK; Goldgar DE; Buys SS; Breast Cancer Family Registry; Janavicius R; Tihomirova L; Tung N; Dorfling CM; van Rensburg EJ; Neuhausen SL; Ding YC; Gerdes A-M; Ejlertsen B; Nielsen FC; Hansen TV; Osorio A; Benitez J; Conejero RA; Segota E; Weitzel JN; Thelander M; Peterlongo P; Radice P; Pensotti V; Dolcetti R; Bonanni B; Peissel B; Zaffaroni D; Scuvera G; Manoukian S; Varesco L; Capone GL; Papi L; Ottini L; Yannoukakos D; Konstantopoulou I; Garber J; Hamann U; Donaldson A; Brady A; Brewer C; Foo C; Evans DG; Frost D; Eccles D; EMBRACE; Douglas F; Cook J; Adlard J; Barwell J; Walker L; Izatt L; Side LE; Kennedy MJ; Tischkowitz M; Rogers MT; Porteous ME; Morrison PJ; Platte R; Eeles R; Davidson R; Hodgson S; Cole T; Godwin AK; Isaacs C; Claes K; De Leeneer K; Meindl A; Gehrig A; Wappenschmidt B; Sutter C; Engel C; Niederacher D; Steinemann D; Plendl H; Kast K; Rhiem K; Ditsch N; Arnold N; Varon-Mateeva R; Schmutzler RK; Preisler-Adams S; Markov NB; Wang-Gohrke S; de Pauw A; Lefol C; Lasset C; Leroux D; Rouleau E; Damiola F; GEMO Study Collaborators; Dreyfus H; Barjhoux L; Golmard L; Uhrhammer N; Bonadona V; Sornin V; Bignon Y-J; Carter J; Van Le L; Piedmonte M; DiSilvestro PA; de la Hoya M; Caldes T; Nevanlinna H; Aittomäki K; Jager A; van den Ouweland AM; Kets CM; Aalfs CM; van Leeuwen FE; Hogervorst FB; Meijers-Heijboer HE; HEBON; Oosterwijk JC; van Roozendaal KE; Rookus MA; Devilee P; van der Luijt RB; Olah E; Diez O; Teulé A; Lazaro C; Blanco I; Del Valle J; Jakubowska A; Sukiennicki G; Gronwald J; Lubinski J; Durda K; Jaworska-Bieniek K; Agnarsson BA; Maugard C; Amadori A; Montagna M; Teixeira MR; Spurdle AB; Foulkes W; Olswold C; Lindor NM; Pankratz VS; Szabo CI; Lincoln A; Jacobs L; Corines M; Robson M; Vijai J; Berger A; Fink-Retter A; Singer CF; Rappaport C; Kaulich DG; Pfeiler G; Tea M-K; Greene MH; Mai PL; Rennert G; Imyanitov EN; Mulligan AM; Glendon G; Andrulis IL; Tchatchou S; Toland AE; Pedersen IS; Thomassen M; Kruse TA; Jensen UB; Caligo MA; Friedman E; Zidan J; Laitman Y; Lindblom A; Melin B; Arver B; Loman N; Rosenquist R; Olopade OI; Nussbaum RL; Ramus SJ; Nathanson KL; Domchek SM; Rebbeck TR; Arun BK; Mitchell G; Karlan BY; Lester J; Orsulic S; Stoppa-Lyonnet D; Thomas G; Simard J; Couch FJ; Offit K; Easton DF; Chenevix-Trench G; Antoniou AC; Mazoyer S; Phelan CM; Sinilnikova OM; Cox DG
Article: MOLECULAR MEDICINE. 2015;20(1):720-728

An entity evolving into a community: defining the common ancestor and evolutionary trajectory of chronic lymphocytic leukemia stereotyped subset #4.

Sutton L-A; Papadopoulos G; Hadzidimitriou A; Papadopoulos S; Kostareli E; Rosenquist R; Tzovaras D; Stamatopoulos K
Article: HAEMATOLOGICA. 2015;100(3):370-376

Targeted next-generation sequencing in chronic lymphocytic leukemia: a high-throughput yet tailored approach will facilitate implementation in a clinical setting.

Sutton L-A; Ljungström V; Mansouri L; Young E; Cortese D; Navrkalova V; Malcikova J; Muggen AF; Trbusek M; Panagiotidis P; Davi F; Belessi C; Langerak AW; Ghia P; Pospisilova S; Stamatopoulos K; Rosenquist R
Article: LEUKEMIA. 2015;29(2):329-336

Recurrent mutations refine prognosis in chronic lymphocytic leukemia.

Baliakas P; Hadzidimitriou A; Sutton L-A; Rossi D; Minga E; Villamor N; Larrayoz M; Kminkova J; Agathangelidis A; Davis Z; Tausch E; Stalika E; Kantorova B; Mansouri L; Scarfò L; Cortese D; Navrkalova V; Rose-Zerilli MJJ; Smedby KE; Juliusson G; Anagnostopoulos A; Makris AM; Navarro A; Delgado J; Oscier D; Belessi C; Stilgenbauer S; Ghia P; Pospisilova S; Gaidano G; Campo E; Strefford JC; Stamatopoulos K; Rosenquist R; European Research Initiative on CLL (ERIC)
Article: BLOOD. 2015;125(5):856-859

Not all IGHV3-21 chronic lymphocytic leukemias are equal: prognostic considerations.

Baliakas P; Agathangelidis A; Hadzidimitriou A; Sutton L-A; Minga E; Tsanousa A; Scarfò L; Davis Z; Yan X-J; Shanafelt T; Plevova K; Sandberg Y; Vojdeman FJ; Boudjogra M; Tzenou T; Chatzouli M; Chu CC; Veronese S; Gardiner A; Mansouri L; Smedby KE; Pedersen LB; Moreno D; Van Lom K; Giudicelli V; Francova HS; Nguyen-Khac F; Panagiotidis P; Juliusson G; Angelis L; Anagnostopoulos A; Lefranc M-P; Facco M; Trentin L; Catherwood M; Montillo M; Geisler CH; Langerak AW; Pospisilova S; Chiorazzi N; Oscier D; Jelinek DF; Darzentas N; Belessi C; Davi F; Ghia P; Rosenquist R; Stamatopoulos K
Article: IMMUNOGENETICS. 2015;67(1):61-66

Immunoglobulin heavy variable (IGHV) genes and alleles: new entities, new names and implications for research and prognostication in chronic lymphocytic leukaemia.

Xochelli A; Agathangelidis A; Kavakiotis I; Minga E; Sutton LA; Baliakas P; Chouvarda I; Giudicelli V; Vlahavas I; Maglaveras N; Bonello L; Trentin L; Tedeschi A; Panagiotidis P; Geisler C; Langerak AW; Pospisilova S; Jelinek DF; Oscier D; Chiorazzi N; Darzentas N; Davi F; Ghia P; Rosenquist R; Hadzidimitriou A; Belessi C; Lefranc M-P; Stamatopoulos K
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2014;167(5):671-680

Impact of ABCB1 single nucleotide polymorphisms 1236C>T and 2677G>T on overall survival in FLT3 wild-type de novo AML patients with normal karyotype.

Jakobsen Falk I; Fyrberg A; Paul E; Nahi H; Hermanson M; Rosenquist R; Höglund M; Palmqvist L; Stockelberg D; Wei Y; Gréen H; Lotfi K
Article: HAEMATOLOGICA. 2014;99(11):1722-1730

Silenced B-cell receptor response to autoantigen in a poor-prognostic subset of chronic lymphocytic leukemia.

Bergh A-C; Evaldsson C; Pedersen LB; Geisler C; Stamatopoulos K; Rosenquist R; Rosén A
Article: LANCET HAEMATOLOGY. 2014;1(2):E74-E84

Clinical effect of stereotyped B-cell receptor immunoglobulins in chronic lymphocytic leukaemia: a retrospective multicentre study.

Baliakas P; Hadzidimitriou A; Sutton L-A; Minga E; Agathangelidis A; Nichelatti M; Tsanousa A; Scarfò L; Davis Z; Yan X-J; Shanafelt T; Plevova K; Sandberg Y; Vojdeman FJ; Boudjogra M; Tzenou T; Chatzouli M; Chu CC; Veronese S; Gardiner A; Mansouri L; Smedby KE; Pedersen LB; van Lom K; Giudicelli V; Francova HS; Nguyen-Khac F; Panagiotidis P; Juliusson G; Angelis L; Anagnostopoulos A; Lefranc M-P; Facco M; Trentin L; Catherwood M; Montillo M; Geisler CH; Langerak AW; Pospisilova S; Chiorazzi N; Oscier D; Jelinek DF; Darzentas N; Belessi C; Davi F; Rosenquist R; Ghia P; Stamatopoulos K
Article: BMC MEDICAL GENETICS. 2014;15:113

A comprehensive evaluation of the role of genetic variation in follicular lymphoma survival.

Baecklund F; Foo J-N; Bracci P; Darabi H; Karlsson R; Hjalgrim H; Rosenquist R; Adami H-O; Glimelius B; Melbye M; Conde L; Liu J; Humphreys K; Skibola CF; Smedby KE
Article: HAEMATOLOGICA. 2014;99(8):1285-1291

MDM2 promotor polymorphism and disease characteristics in chronic lymphocytic leukemia: results of an individual patient data-based meta-analysis.

Benner A; Mansouri L; Rossi D; Majid A; Willander K; Parker A; Bond G; Pavlova S; Nückel H; Merkel O; Ghia P; Montserrat E; Kaderi MA; Rosenquist R; Gaidano G; Dyer MJS; Söderkvist P; Linderholm M; Oscier D; Tvaruzkova Z; Pospisilova S; Dührsen U; Greil R; Döhner H; Stilgenbauer S; Zenz T; European Research Initiative on CLL (ERIC)
Article: EPIGENETICS. 2014;9(6):910-917

microRNA-34b/c on chromosome 11q23 is aberrantly methylated in chronic lymphocytic leukemia.

Deneberg S; Kanduri M; Ali D; Bengtzen S; Karimi M; Qu Y; Kimby E; Mansouri L; Rosenquist R; Lennartsson A; Lehmann S
Article: LEUKEMIA RESEARCH. 2014;38(6):682-690

Identification of B-cell lymphoma subsets by plasma protein profiling using recombinant antibody microarrays.

Pauly F; Smedby KE; Jerkeman M; Hjalgrim H; Ohlsson M; Rosenquist R; Borrebaeck CAK; Wingren C
Article: CLINICAL CANCER RESEARCH. 2014;20(2):323-330

IgG-switched CLL has a distinct immunogenetic signature from the common MD variant: ontogenetic implications.

Vardi A; Agathangelidis A; Sutton L-A; Chatzouli M; Scarfò L; Mansouri L; Douka V; Anagnostopoulos A; Darzentas N; Rosenquist R; Ghia P; Belessi C; Stamatopoulos K
Article: NATURE GENETICS. 2014;46(1):56-60

A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.

Speedy HE; Di Bernardo MC; Sava GP; Dyer MJS; Holroyd A; Wang Y; Sunter NJ; Mansouri L; Juliusson G; Smedby KE; Roos G; Jayne S; Majid A; Dearden C; Hall AG; Mainou-Fowler T; Jackson GH; Summerfield G; Harris RJ; Pettitt AR; Allsup DJ; Bailey JR; Pratt G; Pepper C; Fegan C; Rosenquist R; Catovsky D; Allan JM; Houlston RS
Article: EPIGENETICS. 2013;8(12):1280-1288

A key role for EZH2 in epigenetic silencing of HOX genes in mantle cell lymphoma.

Kanduri M; Sander B; Ntoufa S; Papakonstantinou N; Sutton L-A; Stamatopoulos K; Kanduri C; Rosenquist R
Article: AMERICAN JOURNAL OF HEMATOLOGY. 2013;88(12):1001-1006

Decreased survival in normal karyotype AML with single-nucleotide polymorphisms in genes encoding the AraC metabolizing enzymes cytidine deaminase and 5'-nucleotidase.

Falk IJ; Fyrberg A; Paul E; Nahi H; Hermanson M; Rosenquist R; Höglund M; Palmqvist L; Stockelberg D; Wei Y; Gréen H; Lotfi K
Article: LEUKEMIA. 2013;27(11):2196-2199

Distinct patterns of novel gene mutations in poor-prognostic stereotyped subsets of chronic lymphocytic leukemia: the case of SF3B1 and subset #2.

Strefford JC; Sutton L-A; Baliakas P; Agathangelidis A; Malčíková J; Plevova K; Scarfó L; Davis Z; Stalika E; Cortese D; Cahill N; Pedersen LB; di Celle PF; Tzenou T; Geisler C; Panagiotidis P; Langerak AW; Chiorazzi N; Pospisilova S; Oscier D; Davi F; Belessi C; Mansouri L; Ghia P; Stamatopoulos K; Rosenquist R
Article: BLOOD. 2013;122(15):2673-2682

Two main genetic pathways lead to the transformation of chronic lymphocytic leukemia to Richter syndrome.

Chigrinova E; Rinaldi A; Kwee I; Rossi D; Rancoita PMV; Strefford JC; Oscier D; Stamatopoulos K; Papadaki T; Berger F; Young KH; Murray F; Rosenquist R; Greiner TC; Chan WC; Orlandi EM; Lucioni M; Marasca R; Inghirami G; Ladetto M; Forconi F; Cogliatti S; Votavova H; Swerdlow SH; Stilgenbauer S; Piris MA; Matolcsy A; Spagnolo D; Nikitin E; Zamò A; Gattei V; Bhagat G; Ott G; Zucca E; Gaidano G; Bertoni F
Article: MOLECULAR MEDICINE. 2013;19(1):230-236

Temporal dynamics of clonal evolution in chronic lymphocytic leukemia with stereotyped IGHV4-34/IGKV2-30 antigen receptors: longitudinal immunogenetic evidence.

Sutton L-A; Kostareli E; Stalika E; Tsaftaris A; Anagnostopoulos A; Darzentas N; Rosenquist R; Stamatopoulos K
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2013;210(9):1729-1742

DNA repair genes are selectively mutated in diffuse large B cell lymphomas.

de Miranda NFCC; Peng R; Georgiou K; Wu C; Falk Sörqvist E; Berglund M; Chen L; Gao Z; Lagerstedt K; Lisboa S; Roos F; van Wezel T; Teixeira MR; Rosenquist R; Sundström C; Enblad G; Nilsson M; Zeng Y; Kipling D; Pan-Hammarström Q
Article: LEUKEMIA & LYMPHOMA. 2013;54(8):1769-1779

Molecular characterization of neoplastic and normal "sister" lymphoblastoid B-cell lines from chronic lymphocytic leukemia.

Lanemo Myhrinder A; Hellqvist E; Bergh A-C; Jansson M; Nilsson K; Hultman P; Jonasson J; Buhl AM; Bredo Pedersen L; Jurlander J; Klein E; Weit N; Herling M; Rosenquist R; Rosén A
Article: AMERICAN JOURNAL OF HEMATOLOGY. 2013;88(8):647-651

Short telomere length is associated with NOTCH1/SF3B1/TP53 aberrations and poor outcome in newly diagnosed chronic lymphocytic leukemia patients.

Mansouri L; Grabowski P; Degerman S; Svenson U; Gunnarsson R; Cahill N; Smedby KE; Geisler C; Juliusson G; Roos G; Rosenquist R
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2013;162(2):221-228

rs2072135, a low-penetrance variant for chronic lymphocytic leukaemia?

Sava GP; Speedy HE; Di Bernardo MC; Deaglio S; Karabon L; Frydecka I; Woszczyk D; Rossi D; Gaidano G; Mansouri L; Smedby KE; Juliusson G; Rosenquist R; Catovsky D; Houlston RS
Article: EPIGENETICS. 2013;8(7):720-729

ANGPT2 promoter methylation is strongly associated with gene expression and prognosis in chronic lymphocytic leukemia.

Martinelli S; Kanduri M; Maffei R; Fiorcari S; Bulgarelli J; Marasca R; Rosenquist R
Article: PLOS GENETICS. 2013;9(3):e1003212

Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk.

Couch FJ; Wang X; McGuffog L; Lee A; Olswold C; Kuchenbaecker KB; Soucy P; Fredericksen Z; Barrowdale D; Dennis J; Gaudet MM; Dicks E; Kosel M; Healey S; Sinilnikova OM; Lee A; Bacot F; Vincent D; Hogervorst FBL; Peock S; Stoppa-Lyonnet D; Jakubowska A; kConFab Investigators; Radice P; Schmutzler RK; SWE-BRCA; Domchek SM; Piedmonte M; Singer CF; Friedman E; Thomassen M; Ontario Cancer Genetics Network; Hansen TVO; Neuhausen SL; Szabo CI; Blanco I; Greene MH; Karlan BY; Garber J; Phelan CM; Weitzel JN; Montagna M; Olah E; Andrulis IL; Godwin AK; Yannoukakos D; Goldgar DE; Caldes T; Nevanlinna H; Osorio A; Terry MB; Daly MB; van Rensburg EJ; Hamann U; Ramus SJ; Toland AE; Caligo MA; Olopade OI; Tung N; Claes K; Beattie MS; Southey MC; Imyanitov EN; Tischkowitz M; Janavicius R; John EM; Kwong A; Diez O; Balmaña J; Barkardottir RB; Arun BK; Rennert G; Teo S-H; Ganz PA; Campbell I; van der Hout AH; van Deurzen CHM; Seynaeve C; Gómez Garcia EB; van Leeuwen FE; Meijers-Heijboer HEJ; Gille JJP; Ausems MGEM; Blok MJ; Ligtenberg MJL; Rookus MA; Devilee P; Verhoef S; van Os TAM; Wijnen JT; HEBON; EMBRACE; Frost D; Ellis S; Fineberg E; Platte R; Evans DG; Izatt L; Eeles RA; Adlard J; Eccles DM; Cook J; Brewer C; Douglas F; Hodgson S; Morrison PJ; Side LE; Donaldson A; Houghton C; Rogers MT; Dorkins H; Eason J; Gregory H; McCann E; Murray A; Calender A; Hardouin A; Berthet P; Delnatte C; Nogues C; Lasset C; Houdayer C; Leroux D; Rouleau E; Prieur F; Damiola F; Sobol H; Coupier I; Venat-Bouvet L; Castera L; Gauthier-Villars M; Léoné M; Pujol P; Mazoyer S; Bignon Y-J; GEMO Study Collaborators; Złowocka-Perłowska E; Gronwald J; Lubinski J; Durda K; Jaworska K; Huzarski T; Spurdle AB; Viel A; Peissel B; Bonanni B; Melloni G; Ottini L; Papi L; Varesco L; Tibiletti MG; Peterlongo P; Volorio S; Manoukian S; Pensotti V; Arnold N; Engel C; Deissler H; Gadzicki D; Gehrig A; Kast K; Rhiem K; Meindl A; Niederacher D; Ditsch N; Plendl H; Preisler-Adams S; Engert S; Sutter C; Varon-Mateeva R; Wappenschmidt B; Weber BHF; Arver B; Stenmark-Askmalm M; Loman N; Rosenquist R; Einbeigi Z; Nathanson KL; Rebbeck TR; Blank SV; Cohn DE; Rodriguez GC; Small L; Friedlander M; Bae-Jump VL; Fink-Retter A; Rappaport C; Gschwantler-Kaulich D; Pfeiler G; Tea M-K; Lindor NM; Kaufman B; Shimon Paluch S; Laitman Y; Skytte A-B; Gerdes A-M; Pedersen IS; Moeller ST; Kruse TA; Jensen UB; Vijai J; Sarrel K; Robson M; Kauff N; Mulligan AM; Glendon G; Ozcelik H; Ejlertsen B; Nielsen FC; Jønson L; Andersen MK; Ding YC; Steele L; Foretova L; Teulé A; Lazaro C; Brunet J; Pujana MA; Mai PL; Loud JT; Walsh C; Lester J; Orsulic S; Narod SA; Herzog J; Sand SR; Tognazzo S; Agata S; Vaszko T; Weaver J; Stavropoulou AV; Buys SS; Romero A; de la Hoya M; Aittomäki K; Muranen TA; Duran M; Chung WK; Lasa A; Dorfling CM; Miron A; BCFR; Benitez J; Senter L; Huo D; Chan SB; Sokolenko AP; Chiquette J; Tihomirova L; Friebel TM; Agnarsson BA; Lu KH; Lejbkowicz F; James PA; Hall P; Dunning AM; Tessier D; Cunningham J; Slager SL; Wang C; Hart S; Stevens K; Simard J; Pastinen T; Pankratz VS; Offit K; Easton DF; Chenevix-Trench G; Antoniou AC; CIMBA
Article: LEUKEMIA. 2013;27(1):150-158

450K-array analysis of chronic lymphocytic leukemia cells reveals global DNA methylation to be relatively stable over time and similar in resting and proliferative compartments.

Cahill N; Bergh A-C; Kanduri M; Göransson-Kultima H; Mansouri L; Isaksson A; Ryan F; Smedby KE; Juliusson G; Sundström C; Rosén A; Rosenquist R
Article: EPIGENETICS. 2012;7(12):1435-1442

Distinct transcriptional control in major immunogenetic subsets of chronic lymphocytic leukemia exhibiting subset-biased global DNA methylation profiles.

Kanduri M; Marincevic M; Halldórsdóttir AM; Mansouri L; Junevik K; Ntoufa S; Kultima HG; Isaksson A; Juliusson G; Andersson P-O; Ehrencrona H; Stamatopoulos K; Rosenquist R
Article: ANTICANCER RESEARCH. 2012;32(8):3125-3136

Screening for cytotoxic compounds in poor-prognostic chronic lymphocytic leukemia.

Norberg M; Lindhagen E; Kanduri M; Rickardson L; Sundström C; Stamatopoulos K; Rosenquist R; Åleskog A
Article: JOURNAL OF GENETIC COUNSELING. 2012;21(4):510-526

What information do cancer genetic counselees prioritize?

Hayat Roshanai A; Lampic C; Ingvoldstad C; Askmalm MS; Bjorvatn C; Rosenquist R; Nordin K
Article: AMERICAN JOURNAL OF HEMATOLOGY. 2012;87(7):737-740

Next generation RNA-sequencing in prognostic subsets of chronic lymphocytic leukemia.

Mansouri L; Gunnarsson R; Sutton L-A; Ameur A; Hooper SD; Mayrhofer M; Juliusson G; Isaksson A; Gyllensten U; Rosenquist R
Article: BRITISH JOURNAL OF CANCER. 2012;106(12):2016-2024

Association of PHB 1630 C>T and MTHFR 677 C>T polymorphisms with breast and ovarian cancer risk in BRCA1/2 mutation carriers: results from a multicenter study.

Jakubowska A; Rozkrut D; Antoniou A; Hamann U; Scott RJ; McGuffog L; Healy S; Sinilnikova OM; Rennert G; Lejbkowicz F; Flugelman A; Andrulis IL; Glendon G; Ozcelik H; OCGN; Thomassen M; Paligo M; Aretini P; SWE-BRCA; Kantala J; Aroer B; von Wachenfeldt A; Liljegren A; Loman N; Herbst K; Kristoffersson U; Rosenquist R; Karlsson P; Stenmark-Askmalm M; Melin B; Nathanson KL; Domchek SM; Byrski T; Huzarski T; Gronwald J; Menkiszak J; Cybulski C; Serrano P; Osorio A; Cajal TR; Tsitlaidou M; Benítez J; Gilbert M; HEBON; Rookus M; Aalfs CM; Kluijt I; Boessenkool-Pape JL; Meijers-Heijboer HEJ; Oosterwijk JC; van Asperen CJ; Blok MJ; Nelen MR; van den Ouweland AMW; Seynaeve C; van der Luijt RB; Devilee P; EMBRACE; Easton DF; Peock S; Frost D; Platte R; Ellis SD; Fineberg E; Evans DG; Lalloo F; Eeles R; Jacobs C; Adlard J; Davidson R; Eccles D; Cole T; Cook J; Godwin A; Bove B; GEMO Study Collaborators; Stoppa-Lyonnet D; Caux-Moncoutier V; Belotti M; Tirapo C; Mazoyer S; Barjhoux L; Boutry-Kryza N; Pujol P; Coupier I; Peyrat J-P; Vennin P; Muller D; Fricker J-P; Venat-Bouvet L; Johannsson OT; Isaacs C; Schmutzler R; Wappenschmidt B; Meindl A; Arnold N; Varon-Mateeva R; Niederacher D; Sutter C; Deissler H; Preisler-Adams S; Simard J; Soucy P; Durocher F; Chenevix-Trench G; Beesley J; Chen X; KConFab; Rebbeck T; Couch F; Wang X; Lindor N; Fredericksen Z; Pankratz VS; Peterlongo P; Bonanni B; Fortuzzi S; Peissel B; Szabo C; Mai PL; Loud JT; Lubinski J; CIMBA, the Consortium of Investigators of Modifier
Article: CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2012;12(3):201-206

IGHV3-21 gene frequency in a Swedish cohort of patients with newly diagnosed chronic lymphocytic leukemia.

Cahill N; Sutton L-A; Jansson M; Murray F; Mansouri L; Gunnarsson R; Ryan F; Smedby KE; Geisler C; Juliusson G; Rosenquist R
Article: BLOOD. 2012;119(19):4467-4475

Stereotyped B-cell receptors in one-third of chronic lymphocytic leukemia: a molecular classification with implications for targeted therapies.

Agathangelidis A; Darzentas N; Hadzidimitriou A; Brochet X; Murray F; Yan X-J; Davis Z; van Gastel-Mol EJ; Tresoldi C; Chu CC; Cahill N; Giudicelli V; Tichy B; Pedersen LB; Foroni L; Bonello L; Janus A; Smedby K; Anagnostopoulos A; Merle-Beral H; Laoutaris N; Juliusson G; di Celle PF; Pospisilova S; Jurlander J; Geisler C; Tsaftaris A; Lefranc M-P; Langerak AW; Oscier DG; Chiorazzi N; Belessi C; Davi F; Rosenquist R; Ghia P; Stamatopoulos K
Article: AMERICAN JOURNAL OF HEMATOLOGY. 2012;87(4):361-367

Mantle cell lymphoma displays a homogenous methylation profile: a comparative analysis with chronic lymphocytic leukemia.

Halldórsdóttir AM; Kanduri M; Marincevic M; Mansouri L; Isaksson A; Göransson H; Axelsson T; Agarwal P; Jernberg-Wiklund H; Stamatopoulos K; Sander B; Ehrencrona H; Rosenquist R
Article: PHARMACOGENOMICS JOURNAL. 2012;12(2):111-118

Association of ABCB1 polymorphisms with survival and in vitro cytotoxicty in de novo acute myeloid leukemia with normal karyotype.

Gréen H; Falk IJ; Lotfi K; Paul E; Hermansson M; Rosenquist R; Paul C; Nahi H
Article: BREAST CANCER RESEARCH. 2012;14(1):R33

Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers.

Antoniou AC; Kuchenbaecker KB; Soucy P; Beesley J; Chen X; McGuffog L; Lee A; Barrowdale D; Healey S; Sinilnikova OM; Caligo MA; Loman N; Harbst K; Lindblom A; Arver B; Rosenquist R; Karlsson P; Nathanson K; Domchek S; Rebbeck T; Jakubowska A; Lubinski J; Jaworska K; Durda K; Złowowcka-Perłowska E; Osorio A; Durán M; Andrés R; Benítez J; Hamann U; Hogervorst FB; van Os TA; Verhoef S; Meijers-Heijboer HEJ; Wijnen J; Gómez Garcia EB; Ligtenberg MJ; Kriege M; Collée JM; Ausems MGEM; Oosterwijk JC; Peock S; Frost D; Ellis SD; Platte R; Fineberg E; Evans DG; Lalloo F; Jacobs C; Eeles R; Adlard J; Davidson R; Cole T; Cook J; Paterson J; Douglas F; Brewer C; Hodgson S; Morrison PJ; Walker L; Rogers MT; Donaldson A; Dorkins H; Godwin AK; Bove B; Stoppa-Lyonnet D; Houdayer C; Buecher B; de Pauw A; Mazoyer S; Calender A; Léoné M; Bressac-de Paillerets B; Caron O; Sobol H; Frenay M; Prieur F; Ferrer SU; Mortemousque I; Buys S; Daly M; Miron A; Terry MU; Hopper JL; John EM; Southey M; Goldgar D; Singer CF; Fink-Retter A; Tea M-K; Kaulich DU; Hansen TV; Nielsen FC; Barkardottir RB; Gaudet M; Kirchhoff T; Joseph V; Dutra-Clarke A; Offit K; Piedmonte M; Kirk J; Cohn D; Hurteau J; Byron J; Fiorica J; Toland AE; Montagna M; Oliani C; Imyanitov E; Isaacs C; Tihomirova L; Blanco I; Lazaro C; Teulé A; Valle JD; Gayther SA; Odunsi K; Gross J; Karlan BY; Olah E; Teo S-H; Ganz PA; Beattie MS; Dorfling CM; van Rensburg EU; Diez O; Kwong A; Schmutzler RK; Wappenschmidt B; Engel C; Meindl A; Ditsch N; Arnold N; Heidemann S; Niederacher D; Preisler-Adams S; Gadzicki D; Varon-Mateeva R; Deissler H; Gehrig A; Sutter C; Kast K; Fiebig B; Schäfer D; Caldes T; de la Hoya M; Nevanlinna H; Muranen TA; Lespérance B; Spurdle AB; Neuhausen SL; Ding YC; Wang X; Fredericksen Z; Pankratz VS; Lindor NM; Peterlongo P; Manoukian S; Peissel B; Zaffaroni D; Bonanni B; Bernard L; Dolcetti R; Papi L; Ottini L; Radice P; Greene MH; Loud JT; Andrulis IL; Ozcelik H; Mulligan AU; Glendon G; Thomassen M; Gerdes A-M; Jensen UB; Skytte A-B; Kruse TA; Chenevix-Trench G; Couch FJ; Simard J; Easton DF; CIMBA, SWE-BRCA; HEBON; EMBRACE; GEMO Collaborators Study; kConFab Investigators
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2012;209(2):291-305

Cernunnos influences human immunoglobulin class switch recombination and may be associated with B cell lymphomagenesis.

Du L; Peng R; Björkman A; Filipe de Miranda N; Rosner C; Kotnis A; Berglund M; Liu C; Rosenquist R; Enblad G; Sundström C; Hojjat-Farsangi M; Rabbani H; Teixeira MR; Revy P; Durandy A; Zeng Y; Gennery AR; de Villartay J-P; Pan-Hammarström Q
Article: ONCOIMMUNOLOGY. 2012;1(1):18-27

Lymphoblastoid cell line with B1 cell characteristics established from a chronic lymphocytic leukemia clone by in vitro EBV infection.

Rosén A; Bergh A-C; Gogok P; Evaldsson C; Myhrinder AL; Hellqvist E; Rasul A; Björkholm M; Jansson M; Mansouri L; Liu A; Teh BT; Rosenquist R; Klein E
Article: BLOOD. 2011;118(22):5905-5913

Presence of FLT3-ITD and high BAALC expression are independent prognostic markers in childhood acute myeloid leukemia.

Staffas A; Kanduri M; Hovland R; Rosenquist R; Ommen HB; Abrahamsson J; Forestier E; Jahnukainen K; Jónsson ÓG; Zeller B; Palle J; Lönnerholm G; Hasle H; Palmqvist L; Ehrencrona H; Nordic Society of Pediatric Hematology and Oncolog
Article: BLOOD. 2011;118(11):3088-3095

Is there a role for antigen selection in mantle cell lymphoma? Immunogenetic support from a series of 807 cases.

Hadzidimitriou A; Agathangelidis A; Darzentas N; Murray F; Delfau-Larue M-H; Pedersen LB; Lopez AN; Dagklis A; Rombout P; Beldjord K; Kolstad A; Dreyling MH; Anagnostopoulos A; Tsaftaris A; Mavragani-Tsipidou P; Rosenwald A; Ponzoni M; Groenen P; Ghia P; Sander B; Papadaki T; Campo E; Geisler C; Rosenquist R; Davi F; Pott C; Stamatopoulos K
Article: HAEMATOLOGICA. 2011;96(8):1161-1169

Array-based genomic screening at diagnosis and during follow-up in chronic lymphocytic leukemia.

Gunnarsson R; Mansouri L; Isaksson A; Göransson H; Cahill N; Jansson M; Rasmussen M; Lundin J; Norin S; Buhl AM; Smedby KE; Hjalgrim H; Karlsson K; Jurlander J; Geisler C; Juliusson G; Rosenquist R
Article: HAEMATOLOGICA. 2011;96(8):1153-1160

LPL is the strongest prognostic factor in a comparative analysis of RNA-based markers in early chronic lymphocytic leukemia.

Kaderi MA; Kanduri M; Buhl AM; Sevov M; Cahill N; Gunnarsson R; Jansson M; Smedby KE; Hjalgrim H; Jurlander J; Juliusson G; Mansouri L; Rosenquist R
Article: LEUKEMIA. 2011;25(6):979-984

Immunoglobulin sequence analysis and prognostication in CLL: guidelines from the ERIC review board for reliable interpretation of problematic cases.

Langerak AW; Davi F; Ghia P; Hadzidimitriou A; Murray F; Potter KN; Rosenquist R; Stamatopoulos K; Belessi C; European Research Initiative on CLL (ERIC)
Article: LEUKEMIA RESEARCH. 2011;35(4):438-443

Quantitative evaluation of p16(INK4a) promoter methylation using pyrosequencing in de novo diffuse large B-cell lymphoma.

Zainuddin N; Kanduri M; Berglund M; Lindell M; Amini R-M; Roos G; Sundström C; Enblad G; Rosenquist R
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2011;152(6):743-753

Minimal residual disease assessment in childhood acute lymphoblastic leukaemia: a Swedish multi-centre study comparing real-time polymerase chain reaction and multicolour flow cytometry.

Thörn I; Forestier E; Botling J; Thuresson B; Wasslavik C; Björklund E; Li A; Lindström-Eriksson E; Malec M; Grönlund E; Torikka K; Heldrup J; Abrahamsson J; Behrendtz M; Söderhäll S; Jacobsson S; Olofsson T; Porwit A; Lönnerholm G; Rosenquist R; Sundström C
Article: BLOOD CANCER JOURNAL. 2011;1(3):e12

The novel NF-κB inhibitor IMD-0354 induces apoptosis in chronic lymphocytic leukemia.

Kanduri M; Tobin G; Aleskog A; Nilsson K; Rosenquist R
Article: GENES CHROMOSOMES & CANCER. 2011;50(2):113-121

High-resolution genomic screening in mantle cell lymphoma--specific changes correlate with genomic complexity, the proliferation signature and survival.

Halldórsdóttir AM; Sander B; Göransson H; Isaksson A; Kimby E; Mansouri M; Rosenquist R; Ehrencrona H
Article: LEUKEMIA RESEARCH. 2011;35(2):272-274

TP53 Mutations are infrequent in newly diagnosed chronic lymphocytic leukemia.

Zainuddin N; Murray F; Kanduri M; Gunnarsson R; Smedby KE; Enblad G; Jurlander J; Juliusson G; Rosenquist R
Article: HAEMATOLOGICA. 2010;95(12):2072-2079

Distinct gene expression profiles in subsets of chronic lymphocytic leukemia expressing stereotyped IGHV4-34 B-cell receptors.

Marincevic M; Mansouri M; Kanduri M; Isaksson A; Göransson H; Smedby KE; Jurlander J; Juliusson G; Davi F; Stamatopoulos K; Rosenquist R
Article: FAMILIAL CANCER. 2010;9(4):669-679

Disclosing cancer genetic information within families: perspectives of counselees and their at-risk relatives.

Hayat Roshanai A; Lampic C; Rosenquist R; Nordin K
Article: HAEMATOLOGICA. 2010;95(9):1519-1525

High-density screening reveals a different spectrum of genomic aberrations in chronic lymphocytic leukemia patients with 'stereotyped' IGHV3-21 and IGHV4-34 B-cell receptors.

Marincevic M; Cahill N; Gunnarsson R; Isaksson A; Mansouri M; Göransson H; Rasmussen M; Jansson M; Ryan F; Karlsson K; Adami H-O; Davi F; Jurlander J; Juliusson G; Stamatopoulos K; Rosenquist R
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2010;150(4):473-479

Verification that common variation at 2q37.1, 6p25.3, 11q24.1, 15q23, and 19q13.32 influences chronic lymphocytic leukaemia risk.

Crowther-Swanepoel D; Mansouri M; Enjuanes A; Vega A; Smedby KE; Ruiz-Ponte C; Jurlander J; Juliusson G; Montserrat E; Catovsky D; Campo E; Carracedo A; Rosenquist R; Houlston RS
Article: LEUKEMIA. 2010;24(7):1317-1324

Intraclonal diversification of immunoglobulin light chains in a subset of chronic lymphocytic leukemia alludes to antigen-driven clonal evolution.

Kostareli E; Sutton L-A; Hadzidimitriou A; Darzentas N; Kouvatsi A; Tsaftaris A; Anagnostopoulos A; Rosenquist R; Stamatopoulos K
Article: AMERICAN JOURNAL OF HEMATOLOGY. 2010;85(6):418-425

Identification of uniquely expressed transcription factors in highly purified B-cell lymphoma samples.

Andréasson U; Edén P; Peterson C; Högerkorp C-M; Jerkeman M; Andersen N; Berglund M; Sundström C; Rosenquist R; Borrebaeck CAK; Ek S
Article: LEUKEMIA. 2010;24(5):924-931

Relapsed childhood high hyperdiploid acute lymphoblastic leukemia: presence of preleukemic ancestral clones and the secondary nature of microdeletions and RTK-RAS mutations.

Davidsson J; Paulsson K; Lindgren D; Lilljebjörn H; Chaplin T; Forestier E; Andersen MK; Nordgren A; Rosenquist R; Fioretos T; Young BD; Johansson B
Article: ANNALS OF THE RHEUMATIC DISEASES. 2010;69(4):654-659

Rheumatoid arthritis, treatment with corticosteroids and risk of malignant lymphomas: results from a case-control study.

Hellgren K; Iliadou A; Rosenquist R; Feltelius N; Backlin C; Enblad G; Askling J; Baecklund E
Article: LEUKEMIA RESEARCH. 2010;34(3):301-306

Lipoprotein lipase is differentially expressed in prognostic subsets of chronic lymphocytic leukemia but displays invariably low catalytical activity.

Mansouri M; Sevov M; Fahlgren E; Tobin G; Jondal M; Osorio L; Roos G; Olivecrona G; Rosenquist R
Article: LEUKEMIA RESEARCH. 2010;34(3):335-339

Lack of association between the MDM2 promoter polymorphism SNP309 and clinical outcome in chronic lymphocytic leukemia.

Kaderi MA; Mansouri M; Zainuddin N; Cahill N; Gunnarsson R; Jansson M; Kimby E; Aleskog A; Lundin J; Glimelius B; Melbye M; Juliusson G; Jurlander J; Rosenquist R
Article: NATURE GENETICS. 2010;42(2):132-136

Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk.

Crowther-Swanepoel D; Broderick P; Di Bernardo MC; Dobbins SE; Torres M; Mansouri M; Ruiz-Ponte C; Enjuanes A; Rosenquist R; Carracedo A; Jurlander J; Campo E; Juliusson G; Montserrat E; Smedby KE; Dyer MJS; Matutes E; Dearden C; Sunter NJ; Hall AG; Mainou-Fowler T; Jackson GH; Summerfield G; Harris RJ; Pettitt AR; Allsup DJ; Bailey JR; Pratt G; Pepper C; Fegan C; Parker A; Oscier D; Allan JM; Catovsky D; Houlston RS
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2010;84(2):117-127

Applicability of IG/TCR gene rearrangements as targets for minimal residual disease assessment in a population-based cohort of Swedish childhood acute lymphoblastic leukaemia diagnosed 2002-2006.

Thörn I; Forestier E; Thuresson B; Wasslavik C; Malec M; Li A; Lindström-Eriksson E; Botling J; Barbany G; Jacobsson S; Olofsson T; Porwit A; Sundström C; Rosenquist R
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2010;84(2):109-116

IGHV3-21 gene usage is associated with high TCL1 expression in chronic lymphocytic leukemia.

Mansouri MR; Sevov M; Aleskog A; Jondal M; Merup M; Sundström C; Osorio L; Rosenquist R
Article: BLOOD. 2010;115(2):296-305

Differential genome-wide array-based methylation profiles in prognostic subsets of chronic lymphocytic leukemia.

Kanduri M; Cahill N; Göransson H; Enström C; Ryan F; Isaksson A; Rosenquist R
Article: LEUKEMIA. 2010;24(1):125-132

A different ontogenesis for chronic lymphocytic leukemia cases carrying stereotyped antigen receptors: molecular and computational evidence.

Darzentas N; Hadzidimitriou A; Murray F; Hatzi K; Josefsson P; Laoutaris N; Moreno C; Anagnostopoulos A; Jurlander J; Tsaftaris A; Chiorazzi N; Belessi C; Ghia P; Rosenquist R; Davi F; Stamatopoulos K
Article: AMERICAN JOURNAL OF HEMATOLOGY. 2009;84(12):803-808

Identification of molecular targets associated with transformed diffuse large B cell lymphoma using highly purified tumor cells.

Andréasson U; Dictor M; Jerkeman M; Berglund M; Sundström C; Linderoth J; Rosenquist R; Borrebaeck CAK; Ek S
Article: BLOOD. 2009;114(20):4460-4468

Extensive intraclonal diversification in a subgroup of chronic lymphocytic leukemia patients with stereotyped IGHV4-34 receptors: implications for ongoing interactions with antigen.

Sutton L-A; Kostareli E; Hadzidimitriou A; Darzentas N; Tsaftaris A; Anagnostopoulos A; Rosenquist R; Stamatopoulos K
Article: LEUKEMIA & LYMPHOMA. 2009;50(9):1528-1534

Genome-wide microarray-based comparative genomic hybridization analysis of lymphoplasmacytic lymphomas reveals heterogeneous aberrations.

Buckley PG; Walsh SH; Laurell A; Sundström C; Roos G; Langford CF; Dumanski JP; Rosenquist R
Article: LEUKEMIA & LYMPHOMA. 2009;50(9):1512-1518

Low p14ARF expression in de novo acute myeloid leukemia with normal karyotype is associated with poor survival.

Paul E; Paul E; Uggla B; Deneberg S; Bengtzen S; Hermansson M; Dahlman I; Rosenquist R; Wiman KG; Nahi H
Article: LEUKEMIA RESEARCH. 2009;33(8):1047-1054

Monitoring minimal residual disease with flow cytometry, antigen-receptor gene rearrangements and fusion transcript quantification in Philadelphia-positive childhood acute lymphoblastic leukemia.

Thörn I; Botling J; Hermansson M; Lönnerholm G; Sundström C; Rosenquist R; Barbany G
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2009;83(1):22-34

In vitro activity of 20 agents in different prognostic subgroups of chronic lymphocytic leukemia--rolipram and prednisolone active in cells from patients with poor prognosis.

Lindhagen E; Norberg M; Kanduri M; Tobin G; Säisänen L; Aberg M; Gustafsson MG; Sundström C; Rosenquist R; Aleskog A
Article: PLOS ONE. 2009;4(6):e6057

Quantification of normal cell fraction and copy number neutral LOH in clinical lung cancer samples using SNP array data.

Göransson H; Edlund K; Rydåker M; Rasmussen M; Winquist J; Ekman S; Bergqvist M; Thomas A; Lambe M; Rosenquist R; Holmberg L; Micke P; Botling J; Isaksson A
Article: JOURNAL OF GENETIC COUNSELING. 2009;18(2):185-194

Cancer genetic counselees' self-reported psychological distress, changes in life, and adherence to recommended surveillance programs 3-7 years post counseling.

Hayat Roshanai A; Rosenquist R; Lampic C; Nordin K
Article: MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS. 2009;660(1-2):1-11

Analysis of a set of missense, frameshift, and in-frame deletion variants of BRCA1.

Carvalho M; Pino MA; Karchin R; Beddor J; Godinho-Netto M; Mesquita RD; Rodarte RS; Vaz DC; Monteiro VA; Manoukian S; Colombo M; Ripamonti CB; Rosenquist R; Suthers G; Borg A; Radice P; Grist SA; Monteiro ANA; Billack B
Article: BLOOD. 2009;113(2):403-411

Evidence for the significant role of immunoglobulin light chains in antigen recognition and selection in chronic lymphocytic leukemia.

Hadzidimitriou A; Darzentas N; Murray F; Smilevska T; Arvaniti E; Tresoldi C; Tsaftaris A; Laoutaris N; Anagnostopoulos A; Davi F; Ghia P; Rosenquist R; Stamatopoulos K; Belessi C
Article: LEUKEMIA RESEARCH. 2009;33(1):60-66

TP53 mutations predict for poor survival in de novo diffuse large B-cell lymphoma of germinal center subtype.

Zainuddin N; Berglund M; Wanders A; Ren Z-P; Amini R-M; Lindell M; Kanduri M; Roos G; Rosenquist R; Enblad G
Article: ACTA ONCOLOGICA. 2009;48(7):999-1009

Does enhanced information at cancer genetic counseling improve counselees' knowledge, risk perception, satisfaction and negotiation of information to at-risk relatives?--a randomized study.

Roshanai AH; Rosenquist R; Lampic C; Nordin K
Article: LEUKEMIA & LYMPHOMA. 2008;49(12):2333-2343

Rapamycin shows anticancer activity in primary chronic lymphocytic leukemia cells in vitro, as single agent and in drug combination.

Aleskog A; Norberg M; Nygren P; Rickardson L; Kanduri M; Tobin G; Aberg M; Gustafsson MG; Rosenquist R; Lindhagen E
Article: BMC BIOINFORMATICS. 2008;9:409

Normalization of Illumina Infinium whole-genome SNP data improves copy number estimates and allelic intensity ratios.

Staaf J; Vallon-Christersson J; Lindgren D; Juliusson G; Rosenquist R; Höglund M; Borg A; Ringnér M
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2008;81(3):218-225

U-2973, a novel B-cell line established from a patient with a mature B-cell leukemia displaying concurrent t(14;18) and MYC translocation to a non-IG gene partner.

Boström H; Leuchowius K-J; Hallböök H; Nordgren A; Thörn I; Thorselius M; Rosenquist R; Söderberg O; Sundström C
Article: GENES CHROMOSOMES & CANCER. 2008;47(8):697-711

Screening for copy-number alterations and loss of heterozygosity in chronic lymphocytic leukemia--a comparative study of four differently designed, high resolution microarray platforms.

Gunnarsson R; Staaf J; Jansson M; Ottesen AM; Göransson H; Liljedahl U; Ralfkiaer U; Mansouri M; Buhl AM; Smedby KE; Hjalgrim H; Syvänen A-C; Borg A; Isaksson A; Jurlander J; Juliusson G; Rosenquist R
Article: CANCER LETTERS. 2008;265(1):98-106

Phenotypic protein profiling of different B cell sub-populations using antibody CD-microarrays.

Ellmark P; Högerkorp CM; Ek S; Belov L; Berglund M; Rosenquist R; Christopherson RI; Borrebaeck CAK
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2008;141(1):69-72

Expression of the human germinal-centre-associated lymphoma protein in diffuse large B-cell lymphomas in patients with rheumatoid arthritis.

Baecklund E; Natkunam Y; Backlin C; Iliadou A; Askling J; Ekbom A; Feltelius N; Klareskog L; Enblad G; Lossos IS; Levy R; Sundström C; Rosenquist R
Article: BLOOD. 2008;111(7):3838-3848

A new perspective: molecular motifs on oxidized LDL, apoptotic cells, and bacteria are targets for chronic lymphocytic leukemia antibodies.

Lanemo Myhrinder A; Hellqvist E; Sidorova E; Söderberg A; Baxendale H; Dahle C; Willander K; Tobin G; Bäckman E; Söderberg O; Rosenquist R; Hörkkö S; Rosén A
Article: LEUKEMIA & LYMPHOMA. 2008;49(3):477-487

Characterization of 6q deletions in mature B cell lymphomas and childhood acute lymphoblastic leukemia.

Thelander EF; Ichimura K; Corcoran M; Barbany G; Nordgren A; Heyman M; Berglund M; Mungall A; Rosenquist R; Collins VP; Grandér D; Larsson C; Lagercrantz S
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2008;140(6):665-672

Outcome of ETV6/RUNX1-positive childhood acute lymphoblastic leukaemia in the NOPHO-ALL-1992 protocol: frequent late relapses but good overall survival.

Forestier E; Heyman M; Andersen MK; Autio K; Blennow E; Borgström G; Golovleva I; Heim S; Heinonen K; Hovland R; Johannsson JH; Kerndrup G; Nordgren A; Rosenquist R; Swolin B; Johansson B; Nordic Society of Paediatric Haematology, Oncology; Swedish Cytogenetic Leukaemia Study Group (SCLSG); NOPHO Leukaemia Cytogenetic Study Group (NLCSG)
Article: BLOOD. 2008;111(4):2246-2252

Short telomeres are associated with genetic complexity, high-risk genomic aberrations, and short survival in chronic lymphocytic leukemia.

Roos G; Kröber A; Grabowski P; Kienle D; Bühler A; Döhner H; Rosenquist R; Stilgenbauer S
Article: CANCER LETTERS. 2008;259(2):138-145

B cell lymphomas express CX3CR1 a non-B cell lineage adhesion molecule.

Andréasson U; Ek S; Merz H; Rosenquist R; Andersen N; Jerkeman M; Dictor M; Borrebaeck CAK
Article: BLOOD. 2008;111(3):1524-1533

Stereotyped patterns of somatic hypermutation in subsets of patients with chronic lymphocytic leukemia: implications for the role of antigen selection in leukemogenesis.

Murray F; Darzentas N; Hadzidimitriou A; Tobin G; Boudjogra M; Scielzo C; Laoutaris N; Karlsson K; Baran-Marzsak F; Tsaftaris A; Moreno C; Anagnostopoulos A; Caligaris-Cappio F; Vaur D; Ouzounis C; Belessi C; Ghia P; Davi F; Rosenquist R; Stamatopoulos K
Article: LEUKEMIA. 2008;22(2):339-343

The BCL-2 promoter (-938C>A) polymorphism does not predict clinical outcome in chronic lymphocytic leukemia.

Kaderi MA; Norberg M; Murray F; Merup M; Sundström C; Roos G; Aleskog A; Karlsson K; Axelsson T; Tobin G; Rosenquist R
Article: GENOME BIOLOGY. 2008;9(9):R136

Segmentation-based detection of allelic imbalance and loss-of-heterozygosity in cancer cells using whole genome SNP arrays.

Staaf J; Lindgren D; Vallon-Christersson J; Isaksson A; Göransson H; Juliusson G; Rosenquist R; Höglund M; Borg A; Ringnér M
Article: HAEMATOLOGICA. 2007;92(11):1495-1504

Thioredoxin, produced by stromal cells retrieved from the lymph node microenvironment, rescues chronic lymphocytic leukemia cells from apoptosis in vitro.

Bäckman E; Bergh A-C; Lagerdahl I; Rydberg B; Sundström C; Tobin G; Rosenquist R; Linderholm M; Rosén A
Article: BRITISH JOURNAL OF CANCER. 2007;97(6):769-777

Upregulation of bfl-1 is a potential mechanism of chemoresistance in B-cell chronic lymphocytic leukaemia.

Olsson A; Norberg M; Okvist A; Derkow K; Choudhury A; Tobin G; Celsing F; Osterborg A; Rosenquist R; Jondal M; Osorio LM
Article: LEUKEMIA RESEARCH. 2007;31(9):1219-1230

Detailed assessment of copy number alterations revealing homozygous deletions in 1p and 13q in mantle cell lymphoma.

Flordal Thelander E; Ichimura K; Collins VP; Walsh SH; Barbany G; Hagberg A; Laurell A; Rosenquist R; Larsson C; Lagercrantz S
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2007;138(1):68-71

Mast cell infiltration is a favourable prognostic factor in diffuse large B-cell lymphoma.

Hedström G; Berglund M; Molin D; Fischer M; Nilsson G; Thunberg U; Book M; Sundström C; Rosenquist R; Roos G; Erlanson M; Amini R-M; Enblad G
Article: CELL. 2007;129(5):879-890

Downregulation of death-associated protein kinase 1 (DAPK1) in chronic lymphocytic leukemia.

Raval A; Tanner SM; Byrd JC; Angerman EB; Perko JD; Chen S-S; Hackanson B; Grever MR; Lucas DM; Matkovic JJ; Lin TS; Kipps TJ; Murray F; Weisenburger D; Sanger W; Lynch J; Watson P; Jansen M; Yoshinaga Y; Rosenquist R; de Jong PJ; Coggill P; Beck S; Lynch H; de la Chapelle A; Plass C
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2007;78(4):283-289

Telomere length and correlation with histopathogenesis in B-cell leukemias/lymphomas.

Walsh SH; Grabowski P; Berglund M; Thunberg U; Thorsélius M; Tobin G; Aleskog A; Karlsson K; Sundström C; Laurell A; Enblad G; Rosenquist R; Roos G
Article: BLOOD. 2007;109(7):2989-2998

Comprehensive characterization of IGHV3-21-expressing B-cell chronic lymphocytic leukemia: an Italian multicenter study.

Bomben R; Dal Bo M; Capello D; Benedetti D; Marconi D; Zucchetto A; Forconi F; Maffei R; Ghia EM; Laurenti L; Bulian P; Del Principe MI; Palermo G; Thorsélius M; Degan M; Campanini R; Guarini A; Del Poeta G; Rosenquist R; Efremov DG; Marasca R; Foà R; Gaidano G; Gattei V
Article: HEREDITARY CANCER IN CLINICAL PRACTICE. 2007;5(1):17-24

A hypothesis-generating search for new genetic breast cancer syndromes--a national study in 803 Swedish families.

von Wachenfeldt A; Lindblom A; South Swedish Oncogenetic Study Group; Grönberg H; Einbeigi Z; Rosenquist R; Gardman C; Iselius L
Article: MODERN PATHOLOGY. 2007;20(1):63-75

Genomic imbalances during transformation from follicular lymphoma to diffuse large B-cell lymphoma.

Berglund M; Enblad G; Thunberg U; Amini R-M; Sundström C; Roos G; Erlanson M; Rosenquist R; Larsson C; Lagercrantz S
Article: ARTHRITIS & RHEUMATOLOGY. 2006;54(12):3774-3781

Characteristics of diffuse large B cell lymphomas in rheumatoid arthritis.

Baecklund E; Backlin C; Iliadou A; Granath F; Ekbom A; Amini R-M; Feltelius N; Enblad G; Sundström C; Klareskog L; Askling J; Rosenquist R
Article: BLOOD. 2006;107(7):2889-2894

Strikingly homologous immunoglobulin gene rearrangements and poor outcome in VH3-21-using chronic lymphocytic leukemia patients independent of geographic origin and mutational status.

Thorsélius M; Kröber A; Murray F; Thunberg U; Tobin G; Bühler A; Kienle D; Albesiano E; Maffei R; Dao-Ung L-P; Wiley J; Vilpo J; Laurell A; Merup M; Roos G; Karlsson K; Chiorazzi N; Marasca R; Döhner H; Stilgenbauer S; Rosenquist R
Article: ARTHRITIS & RHEUMATOLOGY. 2006;54(3):692-701

Association of chronic inflammation, not its treatment, with increased lymphoma risk in rheumatoid arthritis.

Baecklund E; Iliadou A; Askling J; Ekbom A; Backlin C; Granath F; Catrina AI; Rosenquist R; Feltelius N; Sundström C; Klareskog L
Article: LEUKEMIA. 2006;20(1):77-81

The G(-248)A polymorphism in the promoter region of the Bax gene does not correlate with prognostic markers or overall survival in chronic lymphocytic leukemia.

Skogsberg S; Tobin G; Kröber A; Kienle D; Thunberg U; Aleskog A; Karlsson K; Laurell A; Merup M; Vilpo J; Sundström C; Roos G; Jernberg-Wiklund H; Döhner H; Nilsson K; Stilgenbauer S; Rosenquist R
Article: LEUKEMIA. 2005;19(8):1452-1458

Insights into the multistep transformation process of lymphomas: IgH-associated translocations and tumor suppressor gene mutations in clonally related composite Hodgkin's and non-Hodgkin's lymphomas.

Schmitz R; Renné C; Rosenquist R; Tinguely M; Distler V; Menestrina F; Lestani M; Stankovic T; Austen B; Bräuninger A; Hansmann M-L; Küppers R
Article: MODERN PATHOLOGY. 2005;18(8):1113-1120

Evaluation of immunophenotype in diffuse large B-cell lymphoma and its impact on prognosis.

Berglund M; Thunberg U; Amini R-M; Book M; Roos G; Erlanson M; Linderoth J; Dictor M; Jerkeman M; Cavallin-Ståhl E; Sundström C; Rehn-Eriksson S; Backlin C; Hagberg H; Rosenquist R; Enblad G
Article: BLOOD. 2005;106(2):681-689

Distinctive gene expression pattern in VH3-21 utilizing B-cell chronic lymphocytic leukemia.

Fält S; Merup M; Tobin G; Thunberg U; Gahrton G; Rosenquist R; Wennborg A
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2005;75(1):34-40

Mitogen induced activation, proliferation and surface antigen expression patterns in unmutated and hypermutated chronic lymphocytic leukemia cells.

Vilpo J; Tobin G; Hulkkonen J; Hurme M; Thunberg U; Sundström C; Vilpo L; Rosenquist R
Article: LEUKEMIA RESEARCH. 2005;29(7):729-734

Lymphoplasmacytic lymphoma/Waldenström's macroglobulinemia derives from an extensively hypermutated B cell that lacks ongoing somatic hypermutation.

Walsh SH; Laurell A; Sundström G; Roos G; Sundström C; Rosenquist R
Article: BLOOD. 2005;105(12):4807-4812

Telomere length as a prognostic parameter in chronic lymphocytic leukemia with special reference to VH gene mutation status.

Grabowski P; Hultdin M; Karlsson K; Tobin G; Aleskog A; Thunberg U; Laurell A; Sundström C; Rosenquist R; Roos G
Article: HAEMATOLOGICA. 2005;90(4):465-469

Patients with chronic lymphocytic leukemia with mutated VH genes presenting with Binet stage B or C form a subgroup with a poor outcome.

Tobin G; Thunberg U; Laurell A; Karlsson K; Aleskog A; Willander K; Söderberg O; Merup M; Vilpo J; Hultdin M; Sundström C; Roos G; Rosenquist R
Article: MODERN PATHOLOGY. 2005;18(3):331-339

Mantle cell lymphomas with clonal immunoglobulin V(H)3-21 gene rearrangements exhibit fewer genomic imbalances than mantle cell lymphomas utilizing other immunoglobulin V(H) genes.

Thelander EF; Walsh SH; Thorsélius M; Laurell A; Landgren O; Larsson C; Rosenquist R; Lagercrantz S
Article: LEUKEMIA RESEARCH. 2005;29(2):153-158

Heterogeneous somatic hypermutation status confounds the cell of origin in hairy cell leukemia.

Thorsélius M; Walsh SH; Thunberg U; Hagberg H; Sundström C; Rosenquist R
Article: LEUKEMIA & LYMPHOMA. 2004;45(12):2451-2454

Similar humoral immunity parameters in chronic lymphocytic leukemia patients independent of VH gene mutation status.

Sinisalo M; Aittoniemi J; Koski T; Tobin G; Thunberg U; Sundström C; Rosenquist R; Käyhty H; Vilpo J
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2004;73(6):407-411

VH gene mutation status and cellular drug resistance in chronic lymphocytic leukaemia.

Aleskog A; Tobin G; Laurell A; Thunberg U; Lindhagen E; Roos G; Nilsson K; Nygren P; Sundström C; Höglund M; Larsson R; Rosenquist R
Article: BLOOD. 2004;104(9):2879-2885

Subsets with restricted immunoglobulin gene rearrangement features indicate a role for antigen selection in the development of chronic lymphocytic leukemia.

Tobin G; Thunberg U; Karlsson K; Murray F; Laurell A; Willander K; Enblad G; Merup M; Vilpo J; Juliusson G; Sundström C; Söderberg O; Roos G; Rosenquist R
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2004;73(3):210-214

Clonally related splenic marginal zone lymphoma and Hodgkin lymphoma with unmutated V gene rearrangements and a 15-yr time gap between diagnoses.

Rosenquist R; Roos G; Erlanson M; Küppers R; Bräuninger A; Hansmann M-L
Article: CANCER GENETICS. 2004;153(1):69-72

Different gene expression in immunoglobulin-mutated and immunoglobulin-unmutated forms of chronic lymphocytic leukemia.

Ferrer A; Ollila J; Tobin G; Nagy B; Thunberg U; Aalto Y; Vihinen M; Vilpo J; Rosenquist R; Knuutila S
Article: LEUKEMIA & LYMPHOMA. 2004;45(2):221-228

V(H)3-21 gene usage in chronic lymphocytic leukemia--characterization of a new subgroup with distinct molecular features and poor survival.

Tobin G; Söderberg O; Thunberg U; Rosenquist R
Article: AMERICAN JOURNAL OF SURGICAL PATHOLOGY. 2003;27(11):1483-1488

Analysis of a clonally related mantle cell and Hodgkin lymphoma indicates Epstein-Barr virus infection of a Hodgkin/Reed-Sternberg cell precursor in a germinal center.

Tinguely M; Rosenquist R; Sundström C; Amini R-M; Küppers R; Hansmann M-L; Bräuninger A
Article: GENES CHROMOSOMES & CANCER. 2003;37(4):417-420

More extensive genetic alterations in unmutated than in hypermutated cases of chronic lymphocytic leukemia.

Karhu R; Tobin G; Thunberg U; Vilpo L; Sundström C; Knuutila S; Rosenquist R; Vilpo J
Article: BLOOD. 2003;101(12):4952-4957

Chronic lymphocytic leukemias utilizing the VH3-21 gene display highly restricted Vlambda2-14 gene use and homologous CDR3s: implicating recognition of a common antigen epitope.

Tobin G; Thunberg U; Johnson A; Eriksson I; Söderberg O; Karlsson K; Merup M; Juliusson G; Vilpo J; Enblad G; Sundström C; Roos G; Rosenquist R
Article: BLOOD. 2003;101(10):4047-4054

Mutated VH genes and preferential VH3-21 use define new subsets of mantle cell lymphoma.

Walsh SH; Thorsélius M; Johnson A; Söderberg O; Jerkeman M; Björck E; Eriksson I; Thunberg U; Landgren O; Ehinger M; Löfvenberg E; Wallman K; Enblad G; Sander B; Porwit-MacDonald A; Dictor M; Olofsson T; Sundström C; Roos G; Rosenquist R
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2003;121(4):566-577

Cytogenetic abnormalities in childhood acute myeloid leukaemia: a Nordic series comprising all children enrolled in the NOPHO-93-AML trial between 1993 and 2001.

Forestier E; Heim S; Blennow E; Borgström G; Holmgren G; Heinonen K; Johannsson J; Kerndrup G; Andersen MK; Lundin C; Nordgren A; Rosenquist R; Swolin B; Johansson B; Nordic Society of Paediatric Haematology and Oncol; Swedish Cytogenetic Leukaemia Study Group (SCLSG); NOPHO Leukaemia Cytogenetic Study Group (NLCSG)
Article: LEUKEMIA RESEARCH. 2003;27(4):337-341

Ex vivo drug and irradiation sensitivities in hypermutated and unmutated forms of chronic lymphocytic leukemia cells.

Kivekäs I; Tobin G; Thunberg U; Vilpo L; Sundström C; Rosenquist R; Vilpo J
Article: BRITISH JOURNAL OF CANCER. 2003;88(4):593-598

Association between telomere length and V(H) gene mutation status in chronic lymphocytic leukaemia: clinical and biological implications.

Hultdin M; Rosenquist R; Thunberg U; Tobin G; Norrback K-F; Johnson A; Sundström C; Roos G
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2003;70(1):53-59

Surface antigen expression and correlation with variable heavy-chain gene mutation status in chronic lymphocytic leukemia.

Vilpo J; Tobin G; Hulkkonen J; Hurme M; Thunberg U; Sundström C; Vilpo L; Rosenquist R
Article: ACTA ONCOLOGICA. 2003;42(7):726-734

Genetic counselling for cancer and risk perception.

Lidén A; Berglund G; Hansson MG; Rosenquist R; Sjödén PO; Nordin K
Article: LANCET. 2002;360(9349):1935-1939

Polymorphism in the P2X7 receptor gene and survival in chronic lymphocytic leukaemia.

Thunberg U; Tobin G; Johnson A; Söderberg O; Padyukov L; Hultdin M; Klareskog L; Enblad G; Sundström C; Roos G; Rosenquist R
Article: CANCER GENETICS. 2002;139(1):38-43

Clonal development of a blastoid mantle cell lymphoma studied with comparative genomic hybridization.

Flordal E; Berglund M; Rosenquist R; Erlanson M; Enblad G; Roos G; Larsson C; Lagercrantz S
Article: LEUKEMIA & LYMPHOMA. 2002;43(11):2179-2189

A novel B-cell line (U-2932) established from a patient with diffuse large B-cell lymphoma following Hodgkin lymphoma.

Amini R-M; Berglund M; Rosenquist R; Von Heideman A; Lagercrantz S; Thunberg U; Bergh J; Sundström C; Glimelius B; Enblad G
Article: EXPERIMENTAL HEMATOLOGY. 2002;30(10):1170-1177

Minimal residual disease quantification in childhood acute lymphoblastic leukemia by real-time polymerase chain reaction using the SYBR green dye.

Li A-H; Forestier E; Rosenquist R; Roos G
Article: JOURNAL OF MEDICAL GENETICS. 2002;39(9):689-694

Coping style, psychological distress, risk perception, and satisfaction in subjects attending genetic counselling for hereditary cancer.

Nordin K; Lidén A; Hansson M; Rosenquist R; Berglund G
Article: MODERN PATHOLOGY. 2002;15(8):807-816

Chromosomal imbalances in diffuse large B-cell lymphoma detected by comparative genomic hybridization.

Berglund M; Enblad G; Flordal E; Lui W-O; Backlin C; Thunberg U; Sundström C; Roos G; Allander SV; Erlanson M; Rosenquist R; Larsson C; Lagercrantz S
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2002;68(4):217-224

Somatic hypermutation and V(H) gene usage in mantle cell lymphoma.

Thorsélius M; Walsh S; Eriksson I; Thunberg U; Johnson A; Backlin C; Enblad G; Sundström C; Roos G; Rosenquist R
Article: BLOOD. 2002;99(6):2262-2264

Somatically mutated Ig V(H)3-21 genes characterize a new subset of chronic lymphocytic leukemia.

Tobin G; Thunberg U; Johnson A; Thörn I; Söderberg O; Hultdin M; Botling J; Enblad G; Sällström J; Sundström C; Roos G; Rosenquist R
Article: LEUKEMIA RESEARCH. 2001;25(12):1033-1045

Detailed clonality analysis of relapsing precursor B acute lymphoblastic leukemia: implications for minimal residual disease detection.

Li AH; Rosenquist R; Forestier E; Lindh J; Roos G
Article: BRITISH JOURNAL OF CANCER. 2000;82(3):601-607

Telomere length and telomerase activity in malignant lymphomas at diagnosis and relapse.

Remes K; Norrback KF; Rosenquist R; Mehle C; Lindh J; Roos G
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 1999;63(4):211-218

Clonal rearrangements in childhood and adult precursor B acute lymphoblastic leukemia: a comparative polymerase chain reaction study using multiple sets of primers.

Li AH; Rosenquist R; Forestier E; Holmberg D; Lindh J; Löfvenberg E; Roos G
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 1999;63(3):171-179

Clonal evolution as judged by immunoglobulin heavy chain gene rearrangements in relapsing precursor-B acute lymphoblastic leukemia.

Rosenquist R; Thunberg U; Li AH; Forestier E; Lönnerholm G; Lindh J; Sundström C; Sällström J; Holmberg D; Roos G
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 1999;62(2):123-128

V(H) gene family utilization in different B-cell lymphoma subgroups.

Rosenquist R; Lindström A; Holmberg D; Lindh J; Roos G
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 1998;61(3):164-172

Low rate of somatic hypermutations characterize progressive B-cell lymphomas.

Rosenquist R; Lindström A; Li AH; Roos G; Lindh J; Holmberg D
Article: ACTA ONCOLOGICA. 1998;37(2):193-200

Alterations of the immunoglobulin heavy chain locus in progressive B-cell lymphomas.

Rosenquist R; Linderholm B; Lindström A; Hagberg H; Sundström C; Roos G; Holmberg D; Lindh J
Article: DIAGNOSTIC MOLECULAR PATHOLOGY. 1997;6(3):140-146

Comparative analysis of detection systems for evaluation of PCR amplified immunoglobulin heavy-chain gene rearrangements.

Thunberg U; Rosenquist R; Lindström A; Lindh J; Sundström C; Roos G; Sällström J
Article: MOLECULAR IMMUNOLOGY. 1997;34(4):305-313

Immunoglobulin VH gene replacements in a T-cell lymphoblastic lymphoma.

Rosenquist R; Lindh J; Roos G; Holmberg D
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Alla övriga publikationer

Review: LEUKEMIA. 2024;38(7):1455-1468

ERIC recommendations for TP53 mutation analysis in chronic lymphocytic leukemia-2024 update.

Malcikova J; Pavlova S; Baliakas P; Chatzikonstantinou T; Tausch E; Catherwood M; Rossi D; Soussi T; Tichy B; Kater AP; Niemann CU; Davi F; Gaidano G; Stilgenbauer S; Rosenquist R; Stamatopoulos K; Ghia P; Pospisilova S
Editorial comment: BLOOD. 2024;143(17):1682-1684

New signature predicts MBL-to-CLL progression.

Rosenquist R
Review: MOLECULAR ASPECTS OF MEDICINE. 2024;96:101250

Current and emerging sequencing-based tools for precision cancer medicine.

Edsjö A; Gisselsson D; Staaf J; Holmquist L; Fioretos T; Cavelier L; Rosenquist R
Letter: LEUKEMIA. 2024;38(3):679-680

Updates of the ERIC recommendations on how to report the results from immunoglobulin heavy variable gene analysis in chronic lymphocytic leukemia.

Chatzikonstantinou T; Agathangelidis A; Chatzidimitriou A; Tresoldi C; Davis Z; Giudicelli V; Kossida S; Belessi C; Rosenquist R; Ghia P; Langerak AW; Davi F; Stamatopoulos K; ERIC, the European Research Initiative on CLL
Review: BLOOD ADVANCES. 2023;7(23):7382-7383

Time to include IGLV3-21R110 status in CLL prognostication?

Rosenquist R
Review: JOURNAL OF INTERNAL MEDICINE. 2023;294(4):437-454

Implementation of precision medicine in healthcare-A European perspective.

Stenzinger A; Moltzen EK; Winkler E; Molnar-Gabor F; Malek N; Costescu A; Jensen BN; Nowak F; Pinto C; Ottersen OP; Schirmacher P; Nordborg J; Seufferlein T; Fröhling S; Edsjö A; Garcia-Foncillas J; Normanno N; Lundgren B; Friedman M; Bolanos N; Tatton-Brown K; Hill S; Rosenquist R
Review: JOURNAL OF INTERNAL MEDICINE. 2023;294(4):413-436

Novel precision medicine approaches and treatment strategies in hematological malignancies.

Rosenquist R; Bernard E; Erkers T; Scott DW; Itzykson R; Rousselot P; Soulier J; Hutchings M; Östling P; Cavelier L; Fioretos T; Smedby KE
Corrigendum: LEUKEMIA. 2023;37(9):1944-1951

Correction: "The 5th edition of The World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms" Leukemia. 2022 Jul;36(7):1720-1748.

Alaggio R; Amador C; Anagnostopoulos I; Attygalle AD; de Oliveira Araujo IB; Berti E; Bhagat G; Borges AM; Boyer D; Calaminici M; Chadburn A; Chan JKC; Cheuk W; Chng W-J; Choi JK; Chuang S-S; Coupland SE; Czader M; Dave SS; de Jong D; Di Napoli A; Du M-Q; Elenitoba-Johnson KS; Ferry J; Geyer J; Gratzinger D; Guitart J; Gujral S; Harris M; Harrison CJ; Hartmann S; Hochhaus A; Jansen PM; Karube K; Kempf W; Khoury J; Kimura H; Klapper W; Kovach AE; Kumar S; Lazar AJ; Lazzi S; Leoncini L; Leung N; Leventaki V; Li X-Q; Lim MS; Liu W-P; Louissaint A; Marcogliese A; Medeiros LJ; Michal M; Miranda RN; Mitteldorf C; Montes-Moreno S; Morice W; Nardi V; Naresh KN; Natkunam Y; Ng S-B; Oschlies I; Ott G; Parrens M; Pulitzer M; Rajkumar SV; Rawstron AC; Rech K; Rosenwald A; Said J; Sarkozy C; Sayed S; Saygin C; Schuh A; Sewell W; Siebert R; Sohani AR; Suzuki R; Tooze R; Traverse-Glehen A; Vega F; Vergier B; Wechalekar AD; Wood B; Xerri L; Xiao W; International Agency for Research on Cancer/World
Letter: ACTA ONCOLOGICA. 2023;62(6):560-564

The BioLymph study - implementing precision medicine approaches in lymphoma diagnostics, treatment and follow-up: feasibility and first results.

Smedby KE; Wästerlid T; Tham E; Haider Z; Joelsson J; Thorvaldsdottir B; Krstic A; Wahlin BE; Foroughi-Asl H; Karlsson C; Eloranta S; Saft L; Palma M; Kwiecinska A; Hansson L; Österborg A; Wirta V; Rassidakis G; Sander B; Sonnevi K; Rosenquist R
Corrigendum: LEUKEMIA. 2023;37(2):504

Correction: Different prognostic impact of recurrent gene mutations in chronic lymphocytic leukemia depending on IGHV gene somatic hypermutation status: a study by ERIC in HARMONY.

Mansouri L; Thorvaldsdottir B; Sutton L-A; Karakatsoulis G; Meggendorfer M; Parker H; Nadeu F; Brieghel C; Laidou S; Moia R; Rossi D; Catherwood M; Kotaskova J; Delgado J; Rodríguez-Vicente AE; Benito R; Rigolin GM; Bonfiglio S; Scarfo L; Mattsson M; Davis Z; Gogia A; Rani L; Baliakas P; Foroughi-Asl H; Jylhä C; Skaftason A; Rapado I; Miras F; Martinez-Lopez J; de la Serna J; Rivas JMH; Thornton P; Larráyoz MJ; Calasanz MJ; Fésüs V; Mátrai Z; Bödör C; Smedby KE; Espinet B; Puiggros A; Gupta R; Bullinger L; Bosch F; Tazón-Vega B; Baran-Marszak F; Oscier D; Nguyen-Khac F; Zenz T; Terol MJ; Cuneo A; Hernández-Sánchez M; Pospisilova S; Mills K; Gaidano G; Niemann CU; Campo E; Strefford JC; Ghia P; Stamatopoulos K; Rosenquist R
Review: FRONTIERS IN ONCOLOGY. 2023;13:1143811

Recent revelations and future directions using single-cell technologies in chronic lymphocytic leukemia.

Oder B; Chatzidimitriou A; Langerak AW; Rosenquist R; Österholm C
Editorial comment: FRONTIERS IN ONCOLOGY. 2023;13:1252189

Editorial: The promise of immunogenetics for precision oncology.

Vlachonikola E; Langerak AW; Rosenquist R; Chatzidimitriou A
Review: CAMB PRISM PRECIS MED. 2023;1:e15

Building a precision medicine infrastructure at a national level: The Swedish experience.

Edsjö A; Lindstrand A; Gisselsson D; Mölling P; Friedman M; Cavelier L; Johansson M; Ehrencrona H; Fagerqvist T; Strid T; Lovmar L; Jacobsson B; Johansson Å; Engstrand L; Wheelock CE; Sikora P; Wirta V; Fioretos T; Rosenquist R; Genomic Medicine Sweden (GMS)
Review: FRONTIERS IN ONCOLOGY. 2023;13:1146486

Precision diagnostics in chronic lymphocytic leukemia: Past, present and future.

Mollstedt J; Mansouri L; Rosenquist R
Letter: NATURE MEDICINE. 2022;28(10):1980-1982

Implementing precision medicine in a regionally organized healthcare system in Sweden.

Fioretos T; Wirta V; Cavelier L; Berglund E; Friedman M; Akhras M; Botling J; Ehrencrona H; Engstrand L; Helenius G; Fagerqvist T; Gisselsson D; Gruvberger-Saal S; Gyllensten U; Heidenblad M; Höglund K; Jacobsson B; Johansson M; Johansson Å; Soller MJ; Landström M; Larsson P; Levin L-Å; Lindstrand A; Lovmar L; Lyander A; Melin M; Nordgren A; Nordmark G; Mölling P; Palmqvist L; Palmqvist R; Repsilber D; Sikora P; Stenmark B; Söderkvist P; Stranneheim H; Strid T; Wheelock CE; Wadelius M; Wedell A; Edsjö A; Rosenquist R
Review: SEMINARS IN CANCER BIOLOGY. 2022;84:32-39

Clinical utility of whole-genome sequencing in precision oncology.

Rosenquist R; Cuppen E; Buettner R; Caldas C; Dreau H; Elemento O; Frederix G; Grimmond S; Haferlach T; Jobanputra V; Meggendorfer M; Mullighan CG; Wordsworth S; Schuh A
Review: SEMINARS IN CANCER BIOLOGY. 2022;84:16-22

Analytical demands to use whole-genome sequencing in precision oncology.

Meggendorfer M; Jobanputra V; Wrzeszczynski KO; Roepman P; de Bruijn E; Cuppen E; Buttner R; Caldas C; Grimmond S; Mullighan CG; Elemento O; Rosenquist R; Schuh A; Haferlach T
Editorial comment: SEMINARS IN CANCER BIOLOGY. 2022;84:1-2

Precision medicine in cancer: A paradigm shift.

Rosenquist R; Fröhling S; Stamatopoulos K
Review: JOURNAL OF INTERNAL MEDICINE. 2022;292(2):221-242

Towards precision medicine in lymphoid malignancies.

Bühler MM; Martin-Subero JI; Pan-Hammarström Q; Campo E; Rosenquist R
Review: LEUKEMIA. 2022;36(8):1961-1968

Immunoglobulin gene sequence analysis in chronic lymphocytic leukemia: the 2022 update of the recommendations by ERIC, the European Research Initiative on CLL.

Agathangelidis A; Chatzidimitriou A; Chatzikonstantinou T; Tresoldi C; Davis Z; Giudicelli V; Kossida S; Belessi C; Rosenquist R; Ghia P; Langerak AW; Davi F; Stamatopoulos K; ERIC, the European Research Initiative on CLL
Editorial comment: BLOOD. 2021;138(23):2305-2307

The more complex, the worse outcome in CLL.

Rosenquist R
Meeting abstract: BLOOD. 2021;138:3515

Mutations of the Novel Tumor Suppressor Gene SAMHD1 Are Frequent and Correlate with Decreased Protein Expression in Peripheral T-Cell Lymphomas (PTCL)

Kokaraki G; Xagoraris I; Da Silva PFN; Sutton LA; Falcao RM; de Souza JES; Osterborg A; Wirta V; Brandell RR; Rassidakis GZ
Editorial comment: JCO PRECISION ONCOLOGY. 2021;5:974-980

Discordant Reporting of a Previously Undescribed Pathogenic Germline BRCA2 Variant in Blood and Tumor Tissue in a Patient With Pancreatic Adenocarcinoma.

Kordes M; Tamborero D; Lagerstedt-Robinson K; Yachnin J; Rosenquist R; Löhr J-M; Gustafsson Liljefors M
Letter: LEUKEMIA & LYMPHOMA. 2021;62(11):2808-2811

Mutations known from B-cell lymphoid malignancies are not found in CD34+ stem cells from patients with lymphoma.

Husby S; Favero F; Rodriguez-Gonzalez FG; Sutton LA; Haastrup EK; Ørskov AD; Hansen JW; Arboe B; Aslan D; Clasen-Linde E; Rahbek Gjerdrum LM; Gørlev JS; Brown P; Fischer-Nielsen A; Rosenquist R; Weischenfeldt J; Grønbæk K
Review: JOURNAL OF INTERNAL MEDICINE. 2021;290(3):602-620

Technological readiness and implementation of genomic-driven precision medicine for complex diseases.

Franks PW; Melén E; Friedman M; Sundström J; Kockum I; Klareskog L; Almqvist C; Bergen SE; Czene K; Hägg S; Hall P; Johnell K; Malarstig A; Catrina A; Hagström H; Benson M; Gustav Smith J; Gomez MF; Orho-Melander M; Jacobsson B; Halfvarson J; Repsilber D; Oresic M; Jern C; Melin B; Ohlsson C; Fall T; Rönnblom L; Wadelius M; Nordmark G; Johansson Å; Rosenquist R; Sullivan PF
Letter: HEMASPHERE. 2021;5(3):e546

Assessing Patients' Knowledge on Chronic Lymphocytic Leukemia: Validation of the ERIC CLL Knowledge Questionnaire in Greece.

Karamanidou C; Xochelli A; Papaioannou M; Moysiadis T; Scarfo L; Mattsson M; Stavroyianni N; Rosenquist R; Ghia P; Stamatopoulos K
Published conference paper: BLOOD. 2021;137(2):216-231

Triggering interferon signaling in T cells with avadomide sensitizes CLL to anti-PD-L1/PD-1 immunotherapy.

Ioannou N; Hagner PR; Stokes M; Gandhi AK; Apollonio B; Fanous M; Papazoglou D; Sutton L-A; Rosenquist R; Amini R-M; Chiu H; Lopez-Girona A; Janardhanan P; Awan FT; Jones J; Kay NE; Shanafelt TD; Tallman MS; Stamatopoulos K; Patten PEM; Vardi A; Ramsay AG
Editorial comment: HAEMATOLOGICA. 2019;104(10):1914-1916

p66Shc deficiency sets the scene for clinically aggressive chronic lymphocytic leukemia.

Rosenquist R
Review: JOURNAL OF INTERNAL MEDICINE. 2019;286(2):118-136

Cell-free tumour DNA testing for early detection of cancer - a potential future tool.

Barbany G; Arthur C; Liedén A; Nordenskjöld M; Rosenquist R; Tesi B; Wallander K; Tham E
Letter: LEUKEMIA. 2019;33(7):1801-1805

Different time-dependent changes of risk for evolution in chronic lymphocytic leukemia with mutated or unmutated antigen B cell receptors.

Moysiadis T; Baliakas P; Rossi D; Catherwood M; Strefford JC; Delgado J; Anagnostopoulos A; Belessi C; Stavroyianni N; Pospisilova S; Oscier D; Gaidano G; Campo E; Rosenquist R; Ghia P; Stamatopoulos K
Letter: HAEMATOLOGICA. 2019;104(5):e208-e210

Long-term real-world results of ibrutinib therapy in patients with relapsed or refractory chronic lymphocytic leukemia: 30-month follow up of the Swedish compassionate use cohort.

Winqvist M; Andersson P-O; Asklid A; Karlsson K; Karlsson C; Lauri B; Lundin J; Mattsson M; Norin S; Sandstedt A; Rosenquist R; Späth F; Hansson L; Österborg A; Swedish CLL Group
Review: HAEMATOLOGICA. 2018;103(12):1956-1968

TP53 aberrations in chronic lymphocytic leukemia: an overview of the clinical implications of improved diagnostics.

Campo E; Cymbalista F; Ghia P; Jäger U; Pospisilova S; Rosenquist R; Schuh A; Stilgenbauer S
Editorial comment: BLOOD. 2018;132(22):2317-2319

Not so lost in translation: RPS15 mutations in CLL.

Ljungström V; Rosenquist R
Editorial comment: SEMINARS IN CANCER BIOLOGY. 2018;51:iv-v

Introduction: Epigenetics in cancer.

Rosenquist R; Esteller M; Plass C
Review: LEUKEMIA. 2018;32(5):1070-1080

ERIC recommendations for TP53 mutation analysis in chronic lymphocytic leukemia-update on methodological approaches and results interpretation.

Malcikova J; Tausch E; Rossi D; Sutton LA; Soussi T; Zenz T; Kater AP; Niemann CU; Gonzalez D; Davi F; Gonzalez Diaz M; Moreno C; Gaidano G; Stamatopoulos K; Rosenquist R; Stilgenbauer S; Ghia P; Pospisilova S; European Research Initiative on Chronic Lymphocyti
Letter: HAEMATOLOGICA. 2018;103(4):E158-E161

No improvement in long-term survival over time for chronic lymphocytic leukemia patients in stereotyped subsets #1 and #2 treated with chemo(immuno)therapy.

Baliakas P; Mattsson M; Hadzidimitriou A; Minga E; Agathangelidis A; Sutton L-A; Scarfo L; Davis Z; Yan X-J; Plevova K; Sandberg Y; Vojdeman FJ; Tzenou T; Chu CC; Veronese S; Mansouri L; Smedby KE; Giudicelli V; Nguyen-Khac F; Panagiotidis P; Juliusson G; Anagnostopoulos A; Lefranc M-P; Trentin L; Catherwood M; Montillo M; Niemann CU; Langerak AW; Pospisilova S; Stavroyianni N; Chiorazzi N; Oscier D; Jelinek DF; Shanafelt T; Darzentas N; Belessi C; Davi F; Ghia P; Rosenquist R; Stamatopoulos K
Editorial comment: JOURNAL OF INTERNAL MEDICINE. 2017;282(5):358-359

Introduction to the symposium 'Targeted therapy in B-cell malignancies'.

Smedby KE; Rosenquist R
Published conference paper: JOURNAL OF INTERNAL MEDICINE. 2017;282(5):371-394

Genetic landscape and deregulated pathways in B-cell lymphoid malignancies.

Rosenquist R; Beà S; Du M-Q; Nadel B; Pan-Hammarström Q
Editorial comment: LEUKEMIA. 2017;31(7):1477-1481

Immunoglobulin gene sequence analysis in chronic lymphocytic leukemia: updated ERIC recommendations.

Rosenquist R; Ghia P; Hadzidimitriou A; Sutton L-A; Agathangelidis A; Baliakas P; Darzentas N; Giudicelli V; Lefranc M-P; Langerak AW; Belessi C; Davi F; Stamatopoulos K
Editorial comment: HAEMATOLOGICA. 2017;102(6):968-971

Immunoglobulin genes in chronic lymphocytic leukemia: key to understanding the disease and improving risk stratification.

Sutton L-A; Hadzidimitriou A; Baliakas P; Agathangelidis A; Langerak AW; Stilgenbauer S; Pospisilova S; Davis Z; Forconi F; Davi F; Ghia P; Rosenquist R; Stamatopoulos K; European Research Initiative on CLL (ERIC)
Review: LEUKEMIA. 2017;31(2):282-291

Antigen receptor stereotypy in chronic lymphocytic leukemia.

Stamatopoulos K; Agathangelidis A; Rosenquist R; Ghia P
Editorial comment: CANCER CELL. 2016;30(5):665-667

Unraveling the DNA Methylome in Mantle Cell Lymphoma: New Insights into the Cellular Origin.

Mansouri L; Rosenquist R
Letter: HAEMATOLOGICA. 2016;101(9):e369-e373

ATM mutations in major stereotyped subsets of chronic lymphocytic leukemia: enrichment in subset #2 is associated with markedly short telomeres.

Navrkalova V; Young E; Baliakas P; Radova L; Sutton L-A; Plevova K; Mansouri L; Ljungström V; Ntoufa S; Davis Z; Juliusson G; Smedby KE; Belessi C; Panagiotidis P; Touloumenidou T; Davi F; Langerak AW; Ghia P; Strefford JC; Oscier D; Mayer J; Stamatopoulos K; Pospisilova S; Rosenquist R; Trbusek M
Review: HAEMATOLOGICA. 2016;101(9):1002-1009

Clinical impact of recurrently mutated genes on lymphoma diagnostics: state-of-the-art and beyond.

Rosenquist R; Rosenwald A; Du M-Q; Gaidano G; Groenen P; Wotherspoon A; Ghia P; Gaulard P; Campo E; Stamatopoulos K; European Research Initiative on CLL (ERIC) and the
Editorial comment: SEMINARS IN CANCER BIOLOGY. 2016;39:1-2

B-cell malignancies: All roads lead to NF-κB activation.

Rosenquist R; Stamatopoulos K
Review: SEMINARS IN CANCER BIOLOGY. 2016;39:40-48

NF-κB activation in chronic lymphocytic leukemia: A point of convergence of external triggers and intrinsic lesions.

Mansouri L; Papakonstantinou N; Ntoufa S; Stamatopoulos K; Rosenquist R
Letter: HAEMATOLOGICA. 2016;101(7):e299-e302

Additional trisomies amongst patients with chronic lymphocytic leukemia carrying trisomy 12: the accompanying chromosome makes a difference.

Baliakas P; Puiggros A; Xochelli A; Sutton L-A; Nguyen-Khac F; Gardiner A; Plevova K; Minga E; Hadzidimitriou A; Walewska R; McCarthy H; Ortega M; Collado R; González T; Granada I; Luño E; Kotašková J; Moysiadis T; Davis Z; Stavroyianni N; Anagnostopoulos A; Strefford JC; Pospisilova S; Davi F; Athanasiadou A; Rosenquist R; Oscier D; Espinet B; Stamatopoulos K
Editorial comment: BLOOD. 2016;127(17):2052-2054

Not all subclones matter in CLL.

Sutton L-A; Rosenquist R
Review: JOURNAL OF INTERNAL MEDICINE. 2016;279(4):347-357

Prognostic indices in chronic lymphocytic leukaemia: where do we stand how do we proceed?

Baliakas P; Mattsson M; Stamatopoulos K; Rosenquist R
Editorial comment: HAEMATOLOGICA. 2016;101(3):263-265

Innovation in the prognostication of chronic lymphocytic leukemia: how far beyond TP53 gene analysis can we go?

Pospisilova S; Sutton L-A; Malcikova J; Tausch E; Rossi D; Montserrat E; Moreno C; Stamatopoulos K; Gaidano G; Rosenquist R; Ghia P; European Research Initiative on CLL (ERIC)
Editorial comment: LEUKEMIA & LYMPHOMA. 2015;56(11):3008-3009

A new piece to the stereotypy "puzzle" in chronic lymphocytic leukemia.

Rosenquist R
Review: SEMINARS IN CANCER BIOLOGY. 2015;34:22-35

The complex interplay between cell-intrinsic and cell-extrinsic factors driving the evolution of chronic lymphocytic leukemia.

Sutton L-A; Rosenquist R
Letter: BLOOD. 2015;126(8):1043-1044

Prognostic relevance of MYD88 mutations in CLL: the jury is still out.

Baliakas P; Hadzidimitriou A; Agathangelidis A; Rossi D; Sutton L-A; Kminkova J; Scarfo L; Pospisilova S; Gaidano G; Stamatopoulos K; Ghia P; Rosenquist R
Letter: LEUKEMIA. 2015;29(3):748-751

Common variation at 12q24.13 (OAS3) influences chronic lymphocytic leukemia risk.

Sava GP; Speedy HE; Di Bernardo MC; Dyer MJS; Holroyd A; Sunter NJ; Marr H; Mansouri L; Deaglio S; Karabon L; Frydecka I; Jamroziak K; Woszczyk D; Juliusson G; Smedby KE; Jayne S; Majid A; Wang Y; Dearden C; Hall AG; Mainou-Fowler T; Jackson GH; Summerfield G; Harris RJ; Pettitt AR; Allsup DJ; Bailey JR; Pratt G; Pepper C; Fegan C; Rosenquist R; Catovsky D; Allan JM; Houlston RS
Review: EXPERT REVIEW OF HEMATOLOGY. 2015;8(1):71-78

Clonal evolution in chronic lymphocytic leukemia: impact of subclonality on disease progression.

Sutton L-A; Rosenquist R
Review: HAEMATOLOGICA. 2015;100(1):7-16

Deciphering the molecular landscape in chronic lymphocytic leukemia: time frame of disease evolution.

Sutton L-A; Rosenquist R
Review: CANCER RESEARCH. 2014;74(16):4211-4216

Immunogenetic studies of chronic lymphocytic leukemia: revelations and speculations about ontogeny and clinical evolution.

Vardi A; Agathangelidis A; Sutton L-A; Ghia P; Rosenquist R; Stamatopoulos K
Letter: BRITISH JOURNAL OF HAEMATOLOGY. 2014;166(4):621-625

The frequency of TP53 gene defects differs between chronic lymphocytic leukaemia subgroups harbouring distinct antigen receptors.

Malcikova J; Stalika E; Davis Z; Plevova K; Trbusek M; Mansouri L; Scarfò L; Baliakas P; Gardiner A; Sutton L-A; Francova HS; Agathangelidis A; Anagnostopoulos A; Tracy I; Makris A; Smardova J; Ghia P; Belessi C; Gonzalez D; Rosenquist R; Oscier D; Pospisilova S; Stamatopoulos K
Letter: LEUKEMIA. 2014;28(3):710-713

On the way towards a 'CLL prognostic index': focus on TP53, BIRC3, SF3B1, NOTCH1 and MYD88 in a population-based cohort.

Cortese D; Sutton L-A; Cahill N; Smedby KE; Geisler C; Gunnarsson R; Juliusson G; Mansouri L; Rosenquist R
Letter: LEUKEMIA. 2014;28(3):694-696

Feasibility of targeted next-generation sequencing of the TP53 and ATM genes in chronic lymphocytic leukemia.

Mansouri L; Sutton L-A; Ljungström V; Sörqvist EF; Gunnarsson R; Smedby KE; Juliusson G; Stamatopoulos K; Nilsson M; Rosenquist R
Editorial comment: SEMINARS IN CANCER BIOLOGY. 2014;24:1-2

The microenvironment in lymphomas--dissecting the complex crosstalk between tumor cells and 'by-stander' cells.

Rosenquist R; Davi F; Ghia P
Review: SEMINARS IN CANCER BIOLOGY. 2014;24:61-70

Lymphoma development in patients with autoimmune and inflammatory disorders--what are the driving forces?

Baecklund E; Smedby KE; Sutton L-A; Askling J; Rosenquist R
Editorial comment: SEMINARS IN CANCER BIOLOGY. 2013;23(6):397-398

Antigens in lymphoma development--current knowledge and future directions.

Rosenquist R; Davi F; Stamatopoulos K
Review: SEMINARS IN CANCER BIOLOGY. 2013;23(6):399-409

Antigen selection in B-cell lymphomas--tracing the evidence.

Sutton L-A; Agathangelidis A; Belessi C; Darzentas N; Davi F; Ghia P; Rosenquist R; Stamatopoulos K
Review: LEUKEMIA & LYMPHOMA. 2013;54(11):2351-2364

Prognostic markers and their clinical applicability in chronic lymphocytic leukemia: where do we stand?

Rosenquist R; Cortese D; Bhoi S; Mansouri L; Gunnarsson R
Review: LEUKEMIA & LYMPHOMA. 2013;54(8):1583-1590

Exploring the genetic landscape in chronic lymphocytic leukemia using high-resolution technologies.

Gunnarsson R; Mansouri L; Rosenquist R
Letter: LEUKEMIA. 2013;27(2):512-514

NOTCH1 and SF3B1 mutations can be added to the hierarchical prognostic classification in chronic lymphocytic leukemia.

Mansouri L; Cahill N; Gunnarsson R; Smedby KE; Tjönnfjord E; Hjalgrim H; Juliusson G; Geisler C; Rosenquist R
Letter: LEUKEMIA. 2013;27(2):510-512

Whole-genome-amplified DNA as a source for mutational analysis underestimates the frequency of mutations in pediatric acute myeloid leukemia.

Rosenquist R; Ehrencrona H; Hasle H; Palle J; Kanduri M
Review: EPIGENETICS. 2013;8(2):138-148

Uncovering the DNA methylome in chronic lymphocytic leukemia.

Cahill N; Rosenquist R
Letter: LEUKEMIA. 2012;26(5):1127-1131

Antigen receptor stereotypy across B-cell lymphoproliferations: the case of IGHV4-59/IGKV3-20 receptors with rheumatoid factor activity.

Kostareli E; Gounari M; Janus A; Murray F; Brochet X; Giudicelli V; Pospisilova S; Oscier D; Foroni L; di Celle PF; Tichy B; Pedersen LB; Jurlander J; Ponzoni M; Kouvatsi A; Anagnostopoulos A; Thompson K; Darzentas N; Lefranc M-P; Belessi C; Rosenquist R; Davi F; Ghia P; Stamatopoulos K
Review: EXPERT REVIEW OF HEMATOLOGY. 2012;5(1):69-79

RNA-based markers as prognostic factors in chronic lymphocytic leukemia.

Sevov M; Rosenquist R; Mansouri L
Letter: BLOOD. 2012;119(4):1087-1088

High ERG gene expression is an unfavorable prognostic marker in pediatric acute myeloid leukemia Response

Staffas A; Kanduri M; Hovland R; Rosenquist R; Ommen HB; Abrahamsson J; Forestier E; Jahnukainen K; Jonsson OG; Zeller B; Palle J; Lonnerholm G; Hasle H; Ehrencrona H; Palmqvist L
Letter: LEUKEMIA. 2012;26(1):170-172

Coexistence of trisomies of chromosomes 12 and 19 in chronic lymphocytic leukemia occurs exclusively in the rare IgG-positive variant.

Ibbotson R; Athanasiadou A; Sutton L-A; Davis Z; Gardiner A; Baliakas P; Gunnarsson R; Anagnostopoulos A; Juliusson G; Rosenquist R; Oscier D; Stamatopoulos K
Letter: LEUKEMIA. 2011;25(12):1904-1908

Impact of TP53 mutation and 17p deletion in mantle cell lymphoma.

Halldórsdóttir AM; Lundin A; Murray F; Mansouri L; Knuutila S; Sundström C; Laurell A; Ehrencrona H; Sander B; Rosenquist R
Review: SEMINARS IN CANCER BIOLOGY. 2011;21(5):299-307

Unlocking the secrets of immunoglobulin receptors in mantle cell lymphoma: implications for the origin and selection of the malignant cells.

Agathangelidis A; Hadzidimitriou A; Rosenquist R; Stamatopoulos K
Letter: LEUKEMIA & LYMPHOMA. 2011;52(6):1146-1149

LMO2 protein expression predicts survival in patients with rheumatoid arthritis and diffuse large B-cell lymphoma.

Baecklund E; Backlin C; Mansouri M; Klareskog L; Askling J; Iliadou AN; Enblad G; Lossos IS; Natkunam Y; Rosenquist R
Review: SEMINARS IN CANCER BIOLOGY. 2010;20(6):400-409

Antigens in chronic lymphocytic leukemia--implications for cell origin and leukemogenesis.

Rosén A; Murray F; Evaldsson C; Rosenquist R
Letter: LEUKEMIA. 2010;24(1):211-215

Large but not small copy-number alterations correlate to high-risk genomic aberrations and survival in chronic lymphocytic leukemia: a high-resolution genomic screening of newly diagnosed patients.

Gunnarsson R; Isaksson A; Mansouri M; Göransson H; Jansson M; Cahill N; Rasmussen M; Staaf J; Lundin J; Norin S; Buhl AM; Smedby KE; Hjalgrim H; Karlsson K; Jurlander J; Juliusson G; Rosenquist R
Letter: LEUKEMIA & LYMPHOMA. 2009;50(5):829-830

Infrequent occurrence of PIK3CA mutations in chronic lymphocytic leukemia.

Marincevic M; Tobin G; Rosenquist R
Editorial comment: JOURNAL OF INTERNAL MEDICINE. 2008;264(6):512-513

Introduction: The role of inflammation, autoimmune disease and infectious agents in development of leukaemia and lymphoma.

Rosenquist R
Letter: BLOOD. 2008;111(12):5756-5757

Response: Or both?

Roos G; Rosenquist R; Stilgenbauer S
Review: LEUKEMIA & LYMPHOMA. 2008;49(6):1042-1049

Molecular genetic characterization reveals new subsets of mantle cell lymphoma.

Thelander EF; Rosenquist R
Review: GENES CHROMOSOMES & CANCER. 2008;47(2):149-158

Clinical and cytogenetic features of pediatric dic(9;20)(p13.2;q11.2)-positive B-cell precursor acute lymphoblastic leukemias: a Nordic series of 24 cases and review of the literature.

Forestier E; Gauffin F; Andersen MK; Autio K; Borgström G; Golovleva I; Gustafsson B; Heim S; Heinonen K; Heyman M; Hovland R; Johannsson JH; Kerndrup G; Rosenquist R; Schoumans J; Swolin B; Johansson B; Nordgren A; Nordic Society of Pediatric Hematology and Oncolog; Swedish Cytogenetic Leukemia Study Group; NOPHO Leukemia Cytogenetic Study Group
Letter: LEUKEMIA. 2008;22(1):212-214

Determination of IGHV gene mutational status in chronic lymphocytic leukemia: bioinformatics advances meet clinical needs.

Davi F; Rosenquist R; Ghia P; Belessi C; Stamatopoulos K
Letter: LEUKEMIA. 2007;21(12):2539-2540

Reply to 'Male preponderance in chronic lymphocytic leukemia utilizing IGHV1-69.' When size of the sample matters.

Ghia P; Belessi C; Daví F; Rosenquist R; Stamatopoulos K
Review: GENES CHROMOSOMES & CANCER. 2007;46(5):440-450

Cytogenetic patterns in ETV6/RUNX1-positive pediatric B-cell precursor acute lymphoblastic leukemia: A Nordic series of 245 cases and review of the literature.

Forestier E; Andersen MK; Autio K; Blennow E; Borgström G; Golovleva I; Heim S; Heinonen K; Hovland R; Johannsson JH; Kerndrup G; Nordgren A; Rosenquist R; Swolin B; Johansson B; Nordic Society of Pediatric Hematology and Oncolog; Swedish Cytogenetic Leukemia Study Group (SCLSG); NOPHO Leukemia Cytogenetic Study Group (NLCSG)
Editorial comment: LEUKEMIA. 2007;21(1):1-3

ERIC recommendations on IGHV gene mutational status analysis in chronic lymphocytic leukemia.

Ghia P; Stamatopoulos K; Belessi C; Moreno C; Stilgenbauer S; Stevenson F; Davi F; Rosenquist R; European Research Initiative on CLL
Letter: BLOOD. 2006;108(10):3623-3624

Subtype preference of the BCL6397G/C polymorphism in germinal-center and non-germinal-center subtypes of diffuse large B-cell lymphoma.

Berglund M; Amini R-M; Book M; Rosenquist R; Roos G; Thunberg U
Review: HEMATOLOGICAL ONCOLOGY. 2006;24(1):7-13

What is the current evidence for antigen involvement in the development of chronic lymphocytic leukemia?

Tobin G; Rosén A; Rosenquist R
Letter: BLOOD. 2005;105(12):4894-4895

The interleukin-10 gene promoter polymorphism (-1082) does not correlate with clinical outcome in diffuse large B-cell lymphoma.

Berglund M; Thunberg U; Roos G; Rosenquist R; Enblad G
Letter: LEUKEMIA. 2005;19(5):871-873

Mcl-1 gene promoter insertions do not correlate with disease outcome, stage or VH gene mutation status in chronic lymphocytic leukaemia.

Tobin G; Skogsberg A; Thunberg U; Laurell A; Aleskog A; Merup M; Sundström C; Roos G; Nilsson K; Rosenquist R
Letter: LEUKEMIA. 2005;19(3):464

Absence of H2AX gene mutations in B-cell leukemias and lymphomas.

Walsh SH; Rosenquist R
Review: MEDICAL ONCOLOGY. 2005;22(3):217-228

Prognostic usage of V(H) gene mutation status and its surrogate markers and the role of antigen selection in chronic lymphocytic leukemia.

Tobin G; Rosenquist R
Review: MEDICAL ONCOLOGY. 2005;22(4):327-341

Immunoglobulin gene analysis of mature B-cell malignancies: reconsideration of cellular origin and potential antigen involvement in pathogenesis.

Walsh SH; Rosenquist R
Letter: BRITISH JOURNAL OF HAEMATOLOGY. 2004;125(6):815-817

Association of the 1513C polymorphism in the P2X7 gene with familial forms of chronic lymphocytic leukaemia.

Dao-Ung L-P; Fuller SJ; Sluyter R; SkarRatt KK; Thunberg U; Tobin G; Byth K; Ban M; Rosenquist R; Stewart GJ; Wiley JS
Review: CURRENT OPINION IN RHEUMATOLOGY. 2004;16(3):254-261

Rheumatoid arthritis and malignant lymphomas.

Baecklund E; Askling J; Rosenquist R; Ekbom A; Klareskog L
Letter: LANCET. 2003;361(9367):1478-1479

P2X7 polymorphism and chronic lymphocytic leukaemia -: Reply

Thunberg U; Tobin G; Johnson A; Enblad G; Rosenquist R
Letter: BLOOD. 2002;100(3):1098-1099

IgV_H3-21 gene usage in chronic lymphocytic leukemia

Tobin G; Thunberg U; Johnson A; Söderberg O; Botling J; Enblad G; Sällström J; Sundström C; Roos G; Rosenquist R
Letter: BLOOD. 2001;97(6):1892-1894

CD38 expression is a poor predictor for VH gene mutational status and prognosis in chronic lymphocytic leukemia.

Thunberg U; Johnson A; Roos G; Thörn I; Tobin G; Sällström J; Sundström C; Rosenquist R
Visa fler

Forskningsbidrag

The molecular landscape of chronic lymphocytic leukemia

Swedish Cancer Society

1 January 2018
The molecular landscape of chronic lymphocytic leukemia

Swedish Cancer Society

1 January 2017
The molecular landscape of chronic lymphocytic leukemia

Swedish Cancer Society

1 January 2016
Characterization of the molecular landscape in chronic lymphocytic leukemia

Swedish Cancer Society

1 January 2015
Characterization of the molecular landscape in chronic lymphocytic leukemia

Swedish Cancer Society

1 January 2014

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KNUT OCH ALICE WALLENBERGS STIFTELSE. 2018

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