Richard Rosenquist Brandell | Karolinska Institutet

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Artiklar

Article: LEUKEMIA. 2025;39(7):1650-1660
ATM aberrations in chronic lymphocytic leukemia: del(11q) rather than ATM mutations is an adverse-prognostic biomarker
Thorvaldsdottir B; Mansouri L; Sutton L-A; Nadeu F; Meggendorfer M; Parker H; Brieghel C; Laidou S; Moia R; Rossi D; Kotaskova J; Delgado J; Rodriguez-Vicente AE; Benito R; Rigolin GM; Bonfiglio S; Scarfo L; Mattsson M; Davis Z; Baliakas P; Rapado I; Miras F; Martinez-Lopez J; de la Serna J; Hernandez Rivas JM; Larrayoz MJ; Calasanz MJ; Smedby KE; Espinet B; Puiggros A; Bullinger L; Bosch F; Tazon-Vega B; Baran-Marszak F; Oscier D; Nguyen-Khac F; Zenz T; Terol MJ; Cuneo A; Hernandez-Sanchez M; Pospisilova S; Gaidano G; Niemann CU; Campo E; Strefford JC; Ghia P; Stamatopoulos K; Rosenquist R
Article: LEUKEMIA. 2025;:1-11
Disease-specific U1 spliceosomal RNA mutations in mature B-cell neoplasms
Nadeu F; Shuai S; Clot G; Hilton LK; Diaz-Navarro A; Martin S; Royo R; Baumann T; Kulis M; Lopez-Oreja I; Cossio M; Lu J; Ljungstroem V; Young E; Plevova K; Knisbacher BA; Lin Z; Hahn CK; Bousquets P; Alcoceba M; Gonzalez M; Colado E; Payer AR; Aymerich M; Terol MJ; Rivas-Delgado A; Enjuanes A; Ruiz-Gaspa S; Chatzikonstantinou T; Haegerstrand D; Jylhae C; Skaftason A; Mansouri L; Stranska K; Doubek M; van Gastel-Mol EJ; Davis Z; Walewska R; Scarfo L; Trentin L; Visentin A; Parikh SA; Rabe KG; Moia R; Armand M; Rossi D; Davi F; Gaidano G; Kay NE; Shanafelt TD; Ghia P; Oscier D; Langerak AW; Bea S; Lopez-Guillermo A; Neuberg D; Wu CJ; Getz G; Pospisilova S; Stamatopoulos K; Rosenquist R; Huber W; Zenz T; Colomer D; Martin-Subero JI; Delgado J; Morin RD; Stein LD; Puente XS; Campo E
Article: HEMASPHERE. 2025;9(1):e70065
Detection of clinically relevant variants in the TP53 gene below 10% allelic frequency: A multicenter study by ERIC, the European Research Initiative on CLL
Pavlova S; Malcikova J; Radova L; Bonfiglio S; Cowland JB; Brieghel C; Andersen MK; Karypidou M; Biderman B; Doubek M; Lazarian G; Rapado I; Vynck M; Porret NA; Andres M; Rosenberg D; Sahar D; Martinez-Laperche C; Buno I; Hindley A; Donaldson D; Sanchez JB; Garcia-Marco JA; Serrano-Alcala A; Ferrer-Lores B; Fernandez-Rodriguez C; Bellosillo B; Stilgenbauer S; Tausch E; Nikdin H; Quinn F; Atkinson E; van de Corput L; Yildiz C; Bilbao-Sieyro C; Florido Y; Thiede C; Schuster C; Stoj A; Czekalska S; Chatzidimitriou A; Laidou S; Bidet A; Dussiau C; Nollet F; Piras G; Monne M; Smirnova S; Nikitin E; Sloma I; Claudel A; Largeaud L; Ysebaert L; Valk PJM; Christian A; Walewska R; Oscier D; Sebastiao M; da Silva MG; Galieni P; Angelini M; Rossi D; Spina V; Matos S; Martins V; Stoklosa T; Pepek M; Baliakas P; Andreu R; Luna I; Kahre T; Murumets U; Pikousova T; Kurucova T; Laird S; Ward D; Alcoceba M; Balanzategui A; Scarfo L; Gandini F; Zapparoli E; Blanco A; Abrisqueta P; Rodriguez-Vicente AE; Benito R; Bravetti C; Davi F; Gameiro P; Martinez-Lopez J; Tazon-Vega B; Baran-Marszak F; Davis Z; Catherwood M; Sudarikov A; Rosenquist R; Niemann CU; Stamatopoulos K; Ghia P; Pospisilova S
Article: JOURNAL OF MEDICAL ECONOMICS. 2024;27(1):1053-1060
Micro-costing of genetic diagnostics in acute leukemia in Sweden: from standard-of-care to whole-genome sequencing
Thangavelu T; Wirta V; Orsmark-Pietras C; Cavelier L; Fioretos T; Barbany G; Olsson-Arvidsson L; Pandzic T; Staffas A; Rosenquist R; Levin L-A
Article: LEUKEMIA. 2024;38(11):2429-2442
The non-canonical BAF chromatin remodeling complex is a novel target of spliceosome dysregulation in SF3B1-mutated chronic lymphocytic leukemia
Hagerstrand D; Oder B; Cortese D; Qu Y; Binzer-Panchal A; Osterholm C; Santos TDP; Rabbani L; Asl HF; Skaftason A; Ljungstrom V; Lundholm A; Koutroumani M; Haider Z; Jylha C; Mollstedt J; Mansouri L; Plevova K; Agathangelidis A; Scarfo L; Armand M; Muggen AF; Kay NE; Shanafelt T; Rossi D; Orre LM; Pospisilova S; Barylyuk K; Davi F; Vesterlund M; Langerak AW; Lehtio J; Ghia P; Stamatopoulos K; Sutton L-A; Rosenquist R
Article: EJHAEM. 2024;5(5):998-1004
Medical history and lifestyle factors have limited impact on time-to-first-treatment in patients with chronic lymphocytic leukemia
Glimelius I; Kleinstern G; Robinson DP; Mansouri L; Rostgaard K; Hjalgrim H; Niemann CU; Mattsson M; Rabe KG; Hampel PJ; Parikh SA; Rosenquist R; Cerhan JR; Slager SL; Smedby KE
Article: HEALTH INFORMATICS JOURNAL. 2024;30(4):14604582241290725
Smart variant filtering - A blueprint solution for massively parallel sequencing-based variant analysis
Brahimllari O; Eloranta S; Georgii-Hemming P; Haider Z; Koch S; Krstic A; Skarp FP; Rosenquist R; Smedby KE; Taylan F; Thorvaldsdottir B; Wirta V; Wasterlid T; Boman M
Article: GENES CHROMOSOMES & CANCER. 2024;63(7):e23257
Precision Diagnostics in Myeloid Malignancies: Development and Validation of a National Capture-Based Gene Panel
Orsmark-Pietras C; Lyander A; Ladenvall C; Hallstrom B; Staffas A; Awier H; Krstic A; Baliakas P; Barbany G; Hakansson CB; Gellerbring A; Hagstrom A; Hellstrom-Lindberg E; Juliusson G; Lazarevic V; Munters A; Pandzic T; Wadelius M; As J; Fogelstrand L; Wirta V; Rosenquist R; Cavelier L; Fioretos T
Article: JOURNAL OF INTERNAL MEDICINE. 2024;295(6):785-803
High-throughput molecular assays for inclusion in personalised oncology trials - State-of-the-art and beyond
Edsjo A; Russnes HG; Lehtio J; Tamborero D; Hovig E; Stenzinger A; Rosenquist R
Article: LEUKEMIA. 2024;38(6):1287-1298
IκBε deficiency accelerates disease development in chronic lymphocytic leukemia
Bordini J; Lenzi C; Frenquelli M; Morabito A; Pseftogas A; Belloni D; Mansouri L; Tsiolas G; Perotta E; Ranghetti P; Gandini F; Genova F; Hagerstrand D; Gavriilidis G; Keisaris S; Pechlivanis N; Davi F; Kay NE; Langerak AW; Pospisilova S; Scarfo L; Makris A; Psomopoulos FE; Stamatopoulos K; Rosenquist R; Campanella A; Ghia P
Article: LANCET REGIONAL HEALTH-EUROPE. 2024;39:100881
Diagnostic yield and clinical impact of germline sequencing in children with CNS and extracranial solid tumors - a nationwide, prospective Swedish study
Tesi B; Robinson KL; Abel F; Stahl TDD; Orrsjoe S; Poluha A; Hellberg M; Wessman S; Samuelsson S; Frisk T; Vogt H; Henning K; Sabel M; Ek T; Pal N; Nyman P; Giraud G; Wille J; Pronk CJ; Noren-Nystroem U; Borssen M; Fili M; Stalhammar G; Herold N; Tettamanti G; Maya-Gonzalez C; Arvidsson L; Rosen A; Ekholm K; Kuchinskaya E; Hallbeck A-L; Nordling M; Palmebaeck P; Kogner P; Smoler GK; Laehteenmaeki P; Fransso S; Martinsson T; Shamik A; Mertens F; Rosenquist R; Wirta V; Tham E; Grillner P; Sandgren J; Ljungman G; Gisselsson D; Taylan F; Nordgren A
Article: JOURNAL OF CLINICAL ONCOLOGY. 2024;42(4):452-466
Genetic Characterization of Primary Mediastinal B-Cell Lymphoma: Pathogenesis and Patient Outcomes
Noerenberg D; Briest F; Hennch C; Yoshida K; Hablesreiter R; Takeuchi Y; Ueno H; Staiger AM; Ziepert M; Asmar F; Locher BN; Toth E; Weber T; Amini R-M; Klapper W; Bouzani M; Poeschel V; Rosenwald A; Held G; Campo E; Ishaque N; Stamatopoulos K; Kanellis G; Anagnostopoulos I; Bullinger L; Goldschmidt N; Zinzani PL; Boedoer C; Rosenquist R; Vassilakopoulos TP; Ott G; Ogawa S; Damm F
Article: LEUKEMIA. 2023;37(11):2237-2249
Frequent ZNF217 mutations lead to transcriptional deregulation of interferon signal transduction via altered chromatin accessibility in B cell lymphoma
Briest F; Noerenberg D; Hennch C; Yoshida K; Hablesreiter R; Nimo J; Sasca D; Kirchner M; Mansouri L; Inoue Y; Wiegand L; Staiger AM; Casadei B; Korkolopoulou P; Weiner J; Lopez-Guillermo A; Warth A; Schneider T; Nagy A; Klapper W; Hummel M; Kanellis G; Anagnostopoulos I; Mertins P; Bullinger L; Rosenquist R; Vassilakopoulos TP; Ott G; Ogawa S; Damm F
Article: HAEMATOLOGICA. 2023;108(10):2664-2676
Subgroup-specific gene expression profiles and mixed epistasis in chronic lymphocytic leukemia.
Lütge A; Lu J; Hüllein J; Walther T; Sellner L; Wu B; Rosenquist R; Oakes CC; Dietrich S; Huber W; Zenz T
Article: GENES CHROMOSOMES & CANCER. 2023;62(9):557-563
Real-world data for precision cancer medicine-A European perspective.
Christopoulos P; Schlenk R; Kazdal D; Blasi M; Lennerz J; Shah R; Budczies J; Malek N; Fröhling S; Rosenquist R; Schirmacher P; Bozorgmehr F; Kuon J; Reck M; Thomas M; Stenzinger A
Article: JOURNAL OF CLINICAL INVESTIGATION. 2023;133(13):e166070
Tumor-activated lymph node fibroblasts suppress T cell function in diffuse large B cell lymphoma
Apollonio B; Spada F; Petrov N; Cozzetto D; Papazoglou D; Jarvis P; Kannambath S; Terranova-Barberio M; Amini R-M; Enblad G; Graham C; Benjamin R; Phillips E; Ellis R; Nuamah R; Saqi M; Calado DP; Rosenquist R; Sutton LA; Salisbury J; Zacharioudakis G; Vardi A; Hagner PR; Gandhi AK; Bacac M; Claus C; Umana P; Jarrett RF; Klein C; Deutsch A; Ramsay AG
Article: CURRENT RESEARCH IN TRANSLATIONAL MEDICINE. 2023;71(3):103401
Establishment and characterization of a novel breast implant-associated anaplastic large cell lymphoma cell line and PDX model (BIA-XR1) with a unique KRAS mutation
Xagoraris I; Stathopoulou K; Aulerio RD; He M; Ketscher A; Jatta K; de Flon FH; Barbany G; Rosenquist R; Westerberg LS; Rassidakis GZ
Article: BLOOD ADVANCES. 2023;7(12):2794-2806
BTK and PLCG2 remain unmutated in one-third of patients with CLL relapsing on ibrutinib
Bonfiglio S; Sutton L-A; Ljungstrom V; Capasso A; Pandzic T; Westrom S; Foroughi-Asl H; Skaftason A; Gellerbring A; Lyander A; Gandini F; Gaidano G; Trentin L; Bonello L; Reda G; Bodor C; Stavroyianni N; Tam CS; Marasca R; Forconi F; Panayiotidis P; Ringshausen I; Jaksic O; Frustaci AM; Iyengar S; Coscia M; Mulligan SP; Ysebaert L; Strugov V; Pavlovsky C; Walewska R; Osterborg A; Cortese D; Ranghetti P; Baliakas P; Stamatopoulos K; Scarfo L; Rosenquist R; Ghia P
Article: JCO PRECISION ONCOLOGY. 2023;7:e2300039
Diagnostic Yield From a Nationwide Implementation of Precision Medicine for all Children With Cancer
Wadensten E; Wessman S; Abel F; De Stahl TD; Tesi B; Pietras CO; Arvidsson L; Taylan F; Fransson S; Vogt H; Poluha A; Pradhananga S; Hellberg M; Lagerstedt-Robinson K; Raj Somarajan P; Samuelsson S; Orrsjo S; Maqbool K; Henning K; Strid T; Ek T; Fagman H; Bontell TO; Martinsson T; Puls F; Kogner P; Wirta V; Pronk CJ; Wille J; Rosenquist R; Nister M; Mertens F; Sabel M; Noren-Nystrom U; Grillner P; Nordgren A; Ljungman G; Sandgren J; Gisselsson D
Article: LAKARTIDNINGEN. 2023;120:22139
Precisionsmedicin kräver samverkan och långsiktighet.
Edsjö A; Fioretos T; Rosenquist R
Article: CANCERS. 2023;15(7):1972
Simultaneous Ultra-Sensitive Detection of Structural and Single Nucleotide Variants Using Multiplex Droplet Digital PCR in Liquid Biopsies from Children with Medulloblastoma
Arthur C; Jylha C; de Stahl TD; Shamikh A; Sandgren J; Rosenquist R; Nordenskjold M; Harila A; Barbany G; Sandvik U; Tham E
Article: LEUKEMIA. 2023;37(2):339-347
Different prognostic impact of recurrent gene mutations in chronic lymphocytic leukemia depending on IGHV gene somatic hypermutation status: a study by ERIC in HARMONY
Mansouri L; Thorvaldsdottir B; Sutton L-A; Karakatsoulis G; Meggendorfer M; Parker H; Nadeu F; Brieghel C; Laidou S; Moia R; Rossi D; Catherwood M; Kotaskova J; Delgado J; Rodriguez-Vicente AE; Benito R; Rigolin GM; Bonfiglio S; Scarfo L; Mattsson M; Davis Z; Gogia A; Rani L; Baliakas P; Foroughi-Asl H; Jylha C; Skaftason A; Rapado I; Miras F; Martinez-Lopez J; de la Serna J; Rivas JMH; Thornton P; Larrayoz MJ; Calasanz MJ; Fesus V; Matrai Z; Bodor C; Smedby KE; Espinet B; Puiggros A; Gupta R; Bullinger L; Bosch F; Tazon-Vega B; Baran-Marszak F; Oscier D; N'Guyen-Khac F; Zenz T; Terol MJ; Cuneo A; Hernandez-Sanchez M; Pospisilova S; Mills K; Gaidano G; Niemann CU; Campo E; Strefford JC; Ghia P; Stamatopoulos K; Rosenquist R
Article: FRONTIERS IN ONCOLOGY. 2023;13:1097942
T cell receptor gene repertoire profiles in subgroups of patients with chronic lymphocytic leukemia bearing distinct genomic aberrations
Vlachonikola E; Pechlivanis N; Karakatsoulis G; Sofou E; Gkoliou G; Jeromin S; Stavroyianni N; Ranghetti P; Scarfo L; Osterholm C; Mansouri L; Notopoulou S; Siorenta A; Anagnostopoulos A; Ghia P; Haferlach C; Rosenquist R; Psomopoulos F; Kouvatsi A; Baliakas P; Stamatopoulos K; Chatzidimitriou A
Article: FRONTIERS IN ONCOLOGY. 2023;13:1217712
Feasibility to use whole-genome sequencing as a sole diagnostic method to detect genomic aberrations in pediatric B-cell acute lymphoblastic leukemia
Rezayee F; Eisfeldt J; Skaftason A; Ofverholm I; Sayyab S; Syvanen AC; Maqbool K; Lilljebjorn H; Johansson B; Olsson-Arvidsson L; Pietras CO; Staffas A; Palmqvist L; Fioretos T; Cavelier L; Fogelstrand L; Nordlund J; Wirta V; Rosenquist R; Barbany G
Article: FRONTIERS IN ONCOLOGY. 2023;13:1176698
Whole-genome informed circulating tumor DNA analysis by multiplex digital PCR for disease monitoring in B-cell lymphomas: a proof-of-concept study
Haider Z; Wasterlid T; Spangberg LD; Rabbani L; Jylha C; Thorvaldsdottir B; Skaftason A; Awier HN; Krstic A; Gellerbring A; Lyander A; Hagglund M; Jeggari A; Rassidakis G; Sonnevi K; Sander B; Rosenquist R; Tham E; Smedby KE
Article: JCO PRECISION ONCOLOGY. 2022;6:e2200245
Implementation of Whole-Genome and Transcriptome Sequencing Into Clinical Cancer Care.
Cuppen E; Elemento O; Rosenquist R; Nikic S; IJzerman M; Zaleski ID; Frederix G; Levin L-Å; Mullighan CG; Buettner R; Pugh TJ; Grimmond S; Caldas C; Andre F; Custers I; Campo E; van Snellenberg H; Schuh A; Nakagawa H; von Kalle C; Haferlach T; Fröhling S; Jobanputra V
Article: BLOOD. 2022;140(21):2193-2227
Genomic profiling for clinical decision making in lymphoid neoplasms
de Leval L; Alizadeh AA; Bergsagel PL; Campo E; Davies A; Dogan A; Fitzgibbon J; Horwitz SM; Melnick AM; Morice WG; Morin RD; Nadel B; Pileri SA; Rosenquist R; Rossi D; Salaverria I; Steidl C; Treon SP; Zelenetz AD; Advani RH; Allen CE; Ansell SM; Chan WC; Cook JR; Cook LB; D'Amore F; Dirnhofer S; Dreyling M; Dunleavy K; Feldman AL; Fend F; Gaulard P; Ghia P; Gribben JG; Hermine O; Hodson DJ; Hsi ED; Inghirami G; Jaffe ES; Karube K; Kataoka K; Klapper W; Kim WS; King RL; Ko YH; LaCasce AS; Lenz G; Martin-Subero JI; Piris MA; Pittaluga S; Pasqualucci L; Quintanilla-Martinez L; Rodig SJ; Rosenwald A; Salles GA; San-Miguel J; Savage KJ; Sehn LH; Semenzato G; Staudt LM; Swerdlow SH; Tam CS; Trotman J; Vose JM; Weigert O; Wilson WH; Winter JN; Wu CJ; Zinzani PL; Zucca E; Bagg A; Scott DW
Article: NATURE COMMUNICATIONS. 2022;13(1):6226
Proteogenomics refines the molecular classification of chronic lymphocytic leukemia
Herbst SA; Vesterlund M; Helmboldt AJ; Jafari R; Siavelis I; Stahl M; Schitter EC; Liebers N; Brinkmann BJ; Czernilofsky F; Roider T; Bruch P-M; Iskar M; Kittai A; Huang Y; Lu J; Richter S; Mermelekas G; Umer HM; Knoll M; Kolb C; Lenze A; Cao X; Osterholm C; Wahnschaffe L; Herling C; Scheinost S; Ganzinger M; Mansouri L; Kriegsmann K; Kriegsmann M; Anders S; Zapatka M; Del Poeta G; Zucchetto A; Bomben R; Gattei V; Dreger P; Woyach J; Herling M; Muller-Tidow C; Rosenquist R; Stilgenbauer S; Zenz T; Huber W; Tausch E; Lehtioe J; Dietrich S
Article: SEMINARS IN CANCER BIOLOGY. 2022;84:242-254
Trailblazing precision medicine in Europe: A joint view by Genomic Medicine Sweden and the Centers for Personalized Medicine, ZPM, in Germany
Stenzinger A; Edsjoe A; Ploeger C; Friedman M; Frohling S; Wirta V; Seufferlein T; Botling J; Duyster J; Akhras M; Thimme R; Fioretos T; Bitzer M; Cavelier L; Schirmacher P; Malek N; Rosenquist R
Article: SEMINARS IN CANCER BIOLOGY. 2022;84:170-183
Precision diagnostics in lymphomas-Recent developments and future directions
Mansouri L; Thorvaldsdottir B; Laidou S; Stamatopoulos K; Rosenquist R
Article: BLOOD. 2022;139(22):3340-3344
Secondary resistance to idelalisib is characterized by upregulation of IGF1R rather than by MAPK/ERK pathway mutations
Tausch E; Ljungstrom V; Agathangelidis A; Zapatka M; Scarfo L; Jebaraj BMC; Yosifov DY; Mueller A; Munugalavadla V; Degenhardt JD; Ghia P; Rosenquist R; Stilgenbauer S
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2022;197(4):431-441
International validation of the EORTC QLQ-CLL17 questionnaire for assessment of health-related quality of life for patients with chronic lymphocytic leukaemia
Oerlemans S; Efficace F; Kieffer JM; Kyriakou C; Xochelli A; Levedahl K; Petranovic D; Borges FC; Bredart A; Shamieh O; Gziskevicius L; Lehmann J; Scholz CW; Caocci G; Molica S; Stamatopoulos K; Panteliadou A-K; Papaioannou M; Alrjoob W; Baliakas P; Rosenquist R; Malak S; Miranda A; Cocks K; van de Poll-Franse L
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2022;108(5):369-378
Identifying patients with chronic lymphocytic leukemia without need of treatment: End of endless watch and wait?
Brieghel C; Galle V; Agius R; Da Cunha-Bang C; Andersen MA; Vlummens P; Mattsson M; Rosenquist R; Smedby KE; Herling CD; Bahlo J; Hallek M; Lundgren JD; Offner F; Niemann CU
Article: BLOOD ADVANCES. 2022;6(8):2657-2666
Incidence and time trends of second primary malignancies after non-Hodgkin lymphoma: a Swedish population-based study
Joelsson J; Wasterlid T; Rosenquist R; Jakobsen LH; El-Galaly TC; Smedby KE; Eloranta S
Article: FRONTIERS IN ONCOLOGY. 2022;12:897280
Impact of the Types and Relative Quantities of IGHV Gene Mutations in Predicting Prognosis of Patients With Chronic Lymphocytic Leukemia
Kaufman M; Yan X-J; Li W; Ghia EM; Langerak AW; Rassenti LZ; Belessi C; Kay NE; Davi F; Byrd JC; Pospisilova S; Brown JR; Catherwood M; Davis Z; Oscier D; Montillo M; Trentin L; Rosenquist R; Ghia P; Barrientos JC; Kolitz JE; Allen SL; Rai KR; Stamatopoulos K; Kipps TJ; Neuberg D; Chiorazzi N
Article: FRONTIERS IN ONCOLOGY. 2022;12:899325
Patient-Specific Assays Based on Whole-Genome Sequencing Data to Measure Residual Disease in Children With Acute Lymphoblastic Leukemia: A Proof of Concept Study
Arthur C; Rezayee F; Mogensen N; Saft L; Rosenquist R; Nordenskjold M; Harila-Saari A; Tham E; Barbany G
Article: GENES CHROMOSOMES & CANCER. 2022;61(1):27-36
Transcriptome sequencing of archived lymphoma specimens is feasible and clinically relevant using exome capture technology
Skaftason A; Qu Y; Abdulla M; Nordlund J; Berglund M; Ednersson SB; Andersson P-O; Enblad G; Amini R-M; Rosenquist R; Mansouri L
Article: FRONTIERS IN MEDICINE. 2022;9:842507
A Study Protocol for Validation and Implementation of Whole-Genome and -Transcriptome Sequencing as a Comprehensive Precision Diagnostic Test in Acute Leukemias
Berglund E; Barbany G; Orsmark-Pietras C; Fogelstrand L; Abrahamsson J; Golovleva I; Hallbook H; Hoglund M; Lazarevic V; Levin L-A; Nordlund J; Noren-Nystrom U; Palle J; Thangavelu T; Palmqvist L; Wirta V; Cavelier L; Fioretos T; Rosenquist R; Clinical GPSGMS
Article: BMJ OPEN. 2021;11(11):e050256
MyPal ADULT study protocol: a randomised clinical trial of the MyPal ePRO-based early palliative care system in adult patients with haematological malignancies
Scarfo L; Karamanidou C; Doubek M; Garani-Papadatos T; Didi J; Pontikoglou C; Ling J; Payne C; Papadaki HA; Rosenquist R; Stavroyianni N; Payne S; Ghia P; Natsiavas P; Maramis C; Stamatopoulos K
Article: BLOOD ADVANCES. 2021;5(13):2788-2792
RPS15 mutations rewire RNA translation in chronic lymphocytic leukemia
Ntoufa S; Gerousi M; Laidou S; Psomopoulos F; Tsiolas G; Moysiadis T; Papakonstantinou N; Mansouri L; Anagnostopoulos A; Stavrogianni N; Pospisilova S; Plevova K; Makris AM; Rosenquist R; Stamatopoulos K
Article: HEMATOLOGICAL ONCOLOGY. 2021;39:73-77
Molecular diagnostics and reporting in lymphoid malignancies: Current status and beyond
Rosenquist R
Article: LAKARTIDNINGEN. 2021;118:21023
[Genomic Medicine Sweden - a national initiative for the broad introduction of precision medicine in Swedish healthcare].
Edsjö A; Friedman M; Rosenquist R
Article: LAKARTIDNINGEN. 2021;118:20186
[Precision diagnostics and therapy in hematological malignancies].
Hellström Lindberg E; Cavelier L; Cammenga J; Andersson P-O; Fioretos T; Rosenquist R
Article: BLOOD. 2021;137(14):1895-1904
Higher-order immunoglobulin repertoire restrictions in CLL: the illustrative case of stereotyped subsets 2 and 169
Gemenetzi K; Psomopoulos F; Carriles AA; Gounari M; Minici C; Plevova K; Sutton L-A; Tsagiopoulou M; Baliakas P; Pasentsis K; Anagnostopoulos A; Sandaltzopoulos R; Rosenquist R; Davi F; Pospisilova S; Ghia P; Stamatopoulos K; Degano M; Chatzidimitriou A
Article: BLOOD. 2021;137(10):1365-1376
Higher-order connections between stereotyped subsets: implications for improved patient classification in CLL
Agathangelidis A; Chatzidimitriou A; Gemenetzi K; Giudicelli V; Karypidou M; Plevova K; Davis Z; Yan X-J; Jeromin S; Schneider C; Pedersen LB; Tschumper RC; Sutton L-A; Baliakas P; Scarfo L; van Gastel EJ; Armand M; Tausch E; Biderman B; Baer C; Bagnara D; Navarro A; de Septenville AL; Guido V; Mitterbauer-Hohendanner G; Dimovski A; Brieghel C; Lawless S; Meggendorfer M; Brazdilova K; Ritgen M; Facco M; Tresoldi C; Visentin A; Patriarca A; Catherwood M; Bonello L; Sudarikov A; Vanura K; Roumelioti M; Francova HS; Moysiadis T; Veronese S; Giannopoulos K; Mansouri L; Karan-Djurasevic T; Sandaltzopoulos R; Bodor C; Fais F; Kater A; Panovska I; Rossi D; Alshemmari S; Panagiotidis P; Costeas P; Espinet B; Antic D; Foroni L; Montillo M; Trentin L; Stavroyianni N; Gaidano G; di Celle PF; Niemann C; Campo E; Anagnostopoulos A; Pott C; Fischer K; Hallek M; Oscier D; Stilgenbauer S; Haferlach C; Jelinek D; Chiorazzi N; Pospisilova S; Lefranc M-P; Kossida S; Langerak AW; Belessi C; Davi F; Rosenquist R; Ghia P; Stamatopoulos K
Article: HAEMATOLOGICA. 2021;106(3):682-691
Comparative analysis of targeted next-generation sequencing panels for the detection of gene mutations in chronic lymphocytic leukemia: an ERIC multi-center study
Sutton L-A; Ljungstrom V; Enjuanes A; Cortese D; Skaftason A; Tausch E; Kozubik KS; Nadeu F; Armand M; Malcikova J; Pandzic T; Forster J; Davis Z; Oscier D; Rossi D; Ghia P; Strefford JC; Pospisilova S; Stilgenbauer S; Davi F; Campo E; Stamatopoulos K; Rosenquist R
Article: FRONTIERS IN ONCOLOGY. 2021;11:740083
Consistent B Cell Receptor Immunoglobulin Features Between Siblings in Familial Chronic Lymphocytic Leukemia
Kolijn PM; Muggen AF; Ljungstrom V; Agathangelidis A; Wolvers-Tettero ILM; Beverloo HB; Pal K; Hengeveld PJ; Darzentas N; Hendriks RW; van Dongen JJM; Rosenquist R; Langerak AW
Article: HAEMATOLOGICA. 2021;106(1):87-97
Genomic arrays identify high-risk chronic lymphocytic leukemia with genomic complexity: a multicenter study
Leeksma AC; Baliakas P; Moysiadis T; Puiggros A; Plevova K; van der Kevie-Kersemaekers A-M; Posthuma H; Rodriguez-Vicente AE; Tran AN; Barbany G; Mansouri L; Gunnarsson R; Parker H; van den Berg E; Bellido M; Davis Z; Wall M; Scarpelli I; Osterborg A; Hansson L; Jarosova M; Ghia P; Poddighe P; Espinet B; Pospisilova S; Tam C; Ysebaert L; Nguyen-Khac F; Oscier D; Haferlach C; Schoumans J; Stevens-Kroef M; Eldering E; Stamatopoulos K; Rosenquist R; Strefford JC; Mellink C; Kater AP
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2020;105(6):779-785
Concordance in survival among first-degree relatives diagnosed with indolent lymphoid malignancies including chronic lymphocytic leukemia
Baecklund F; Ekberg S; Rosenquist R; Askling J; Eloranta S; Smedby KE
Article: HAEMATOLOGICA. 2020;105(11):2598-2607
Prognostic impact of prevalent chronic lymphocytic leukemia stereotyped subsets: analysis within prospective clinical trials of the German CLL Study Group
Jaramillo S; Agathangelidis A; Schneider C; Bahlo J; Robrecht S; Tausch E; Bloehdorn J; Hoechstetter M; Fischer K; Eichhorst B; Goede V; Hallek M; Doehner H; Rosenquist R; Ghia P; Stamatopoulos K; Stilgenbauer S
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2020;191(3):426-432
Risk-adapted bendamustine plus rituximab is a tolerable treatment alternative for elderly patients with chronic lymphocytic leukaemia: a regional real-world report on 141 consecutive Swedish patients
Mattsson A; Sylvan SE; Asklid A; Wiggh J; Winqvist M; Lundin J; Mansouri L; Rosenquist R; Johansson H; Osterborg A; Hansson L
Article: LEUKEMIA. 2020;34(10):2545-2551
Immunoglobulin gene analysis in chronic lymphocytic leukemia in the era of next generation sequencing
Davi F; Langerak AW; de Septenville AL; Kolijn PM; Hengeveld PJ; Chatzidimitriou A; Bonfiglio S; Sutton L-A; Rosenquist R; Ghia P; Stamatopoulos K
Article: BLOOD. 2020;135(21):1859-1869
International prognostic score for asymptomatic early-stage chronic lymphocytic leukemia
Condoluci A; di Bergamo LT; Langerbeins P; Hoechstetter MA; Herling CD; De Paoli L; Delgado J; Rabe KG; Gentile M; Doubek M; Mauro FR; Chiodin G; Mattsson M; Bahlo J; Cutrona G; Kotaskova J; Deambrogi C; Smedby KE; Spina V; Bruscaggin A; Wu W; Moia R; Bianchi E; Gerber B; Zucca E; Gillessen S; Ghielmini M; Cavalli F; Stussi G; Hess MA; Baumann TS; Neri A; Ferrarini M; Rosenquist R; Forconi F; Foa R; Pospisilova S; Morabito F; Stilgenbauer S; Doehner H; Parikh SA; Wierda WG; Montserrat E; Gaidano G; Hallek M; Rossi D
Article: CLINICAL CANCER RESEARCH. 2020;26(6):1507-1515
The Number of Signaling Pathways Altered by Driver Mutations in Chronic Lymphocytic Leukemia Impacts Disease Outcome
Brieghel C; da Cunha-Bang C; Yde CW; Schmidt AY; Kinalis S; Nadeu F; Andersen MA; Jacobsen LO; Andersen MK; Pedersen LB; Delgado J; Baumann T; Mattsson M; Mansouri L; Rosenquist R; Campo E; Nielsen FC; Niemann CU
Article: AMERICAN JOURNAL OF HEMATOLOGY. 2020;95(1):57-67
Cell-of-origin determined by both gene expression profiling and immunohistochemistry is the strongest predictor of survival in patients with diffuse large B-cell lymphoma
Abdulla M; Hollander P; Pandzic T; Mansouri L; Ednersson SB; Andersson P-O; Hultdin M; Fors M; Erlanson M; Degerman S; Petersen HM; Asmar F; Gronbaek K; Enblad G; Cavelier L; Rosenquist R; Amini R-M
Article: CLINICAL EPIGENETICS. 2019;11(1):177
DNA methylation profiles in chronic lymphocytic leukemia patients treated with chemoimmunotherapy
Tsagiopoulou M; Papakonstantinou N; Moysiadis T; Mansouri L; Ljungstrom V; Duran-Ferrer M; Malousi A; Queiros AC; Plevova K; Bhoi S; Kollia P; Oscier D; Anagnostopoulos A; Trentin L; Ritgen M; Pospisilova S; Stavroyianni N; Ghia P; Martin-Subero JI; Pott C; Rosenquist R; Stamatopoulos K
Article: EPIGENETICS. 2019;14(11):1125-1140
EZH2 upregulates the PI3K/AKT pathway through IGF1R and MYC in clinically aggressive chronic lymphocytic leukaemia
Kosalai ST; Morsy MHA; Papakonstantinou N; Mansouri L; Stavroyianni N; Kanduri C; Stamatopoulos K; Rosenquist R; Kanduri M
Article: LEUKEMIA. 2019;33(10):2416-2428
Inhibition of SYK or BTK augments venetoclax sensitivity in SHP1-negative/BCL-2-positive diffuse large B-cell lymphoma
Sasi BK; Martines C; Xerxa E; Porro F; Kalkan H; Fazio R; Turkalj S; Bojnik E; Pyrzynska B; Stachura J; Zerrouqi A; Bobrowicz M; Winiarska M; Priebe V; Bertoni F; Mansouri L; Rosenquist R; Efremov DG
Article: BLOOD ADVANCES. 2019;3(16):2474-2481
Clinical significance of DNA methylation in chronic lymphocytic leukemia patients: results from 3 UK clinical trials
Wojdacz TK; Amarasinghe HE; Kadalayil L; Beattie A; Forster J; Blakemore SJ; Parker H; Bryant D; Larrayoz M; Clifford R; Robbe P; Davis ZA; Else M; Howard DR; Stamatopoulos B; Steele AJ; Rosenquist R; Collins A; Pettitt AR; Hillmen P; Plass C; Schuh A; Catovsky D; Oscier DG; Rose-Zerilli MJJ; Oakes CC; Strefford JC
Article: BLOOD ADVANCES. 2019;3(12):1891-1896
Inhibition of EZH2 and immune signaling exerts synergistic antitumor effects in chronic lymphocytic leukemia
Chartomatsidou E; Ntoufa S; Kotta K; Rovida A; Akritidou MA; Belloni D; Ferrero E; Trangas T; Stavroyianni N; Anagnostopoulos A; Rosenquist R; Ghia P; Papakonstantinou N; Stamatopoulos K
Article: SCIENCE TRANSLATIONAL MEDICINE. 2019;11(497):eaav5599
Targetable genetic alterations of TCF4 (E2-2) drive immunoglobulin expression in diffuse large B cell lymphoma
Jain N; Hartert K; Tadros S; Fiskus W; Havranek O; Ma MCJ; Bouska A; Heavican T; Kumar D; Deng Q; Moore D; Pak C; Liu CL; Gentles AJ; Hartmann E; Kridel R; Smedby KE; Juliusson G; Rosenquist R; Gascoyne RD; Rosenwald A; Giancotti F; Neelapu SS; Westin J; Vose JM; Lunning MA; Greiner T; Rodig S; Iqbal J; Alizadeh AA; Davis RE; Bhalla K; Green MR
Article: INTERNATIONAL JOURNAL OF CANCER. 2019;144(11):2695-2706
Integrated epigenomic and transcriptomic analysis reveals TP63 as a novel player in clinically aggressive chronic lymphocytic leukemia
Papakonstantinou N; Ntoufa S; Tsagiopoulou M; Moysiadis T; Bhoi S; Malousi A; Psomopoulos F; Mansouri L; Laidou S; Papazoglou D; Gounari M; Pasentsis K; Plevova K; Kuci-Emruli V; Duran-Ferrer M; Davis Z; Ek S; Rossi D; Gaidano G; Ritgen M; Oscier D; Stavroyianni N; Pospisilova S; Davi F; Ghia P; Hadzidimitriou A; Belessi C; Martin-Subero JI; Pott C; Rosenquist R; Stamatopoulos K
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2019;185(4):708-712
Expression of GNAZ, encoding the Gα_z protein, predicts survival in mantle cell lymphoma
Mundt F; Merrien M; Nygren L; Sutton LA; Christensson B; Wahlin BE; Rosenquist R; Sander B; Wasik AM
Article: JOURNAL OF PATHOLOGY. 2019;247(4):416-421
Disease-biased and shared characteristics of the immunoglobulin gene repertoires in marginal zone B cell lymphoproliferations
Xochelli A; Bikos V; Polychronidou E; Galigalidou C; Agathangelidis A; Charlotte F; Moschonas P; Davis Z; Colombo M; Roumelioti M; Sutton L-A; Groenen P; van den Brand M; Boudjoghra M; Algara P; Traverse-Glehen A; Ferrer A; Stalika E; Karypidou M; Kanellis G; Kalpadakis C; Mollejo M; Pangalis G; Vlamos P; Amini R-M; Pospisilova S; Gonzalez D; Ponzoni M; Anagnostopoulos A; Giudicelli V; Lefranc M-P; Espinet B; Panagiotidis P; Piris MA; Du M-Q; Rosenquist R; Papadaki T; Belessi C; Ferrarini M; Oscier D; Tzovaras D; Ghia P; Davi F; Hadzidimitriou A; Stamatopoulos K
Article: BLOOD ADVANCES. 2019;3(3):384-396
Genome-wide promoter methylation of hairy cell leukemia
Arribas AJ; Rinaldi A; Chiodin G; Kwee I; Mensah AA; Cascione L; Rossi D; Kanduri M; Rosenquist R; Zucca E; Johnson PW; Gaidano G; Oakes CC; Bertoni F; Forconi F
Article: HAEMATOLOGICA. 2019;104(2):360-369
Tailored approaches grounded on immunogenetic features for refined prognostication in chronic lymphocytic leukemia
Baliakas P; Moysiadis T; Hadzidimitriou A; Xochelli A; Jeromin S; Agathangelidis A; Mattsson M; Sutton L-A; Minga E; Scarfo L; Rossi D; Davis Z; Villamor N; Parker H; Kotaskova J; Stalika E; Plevova K; Mansouri L; Cortese D; Navarro A; Delgado J; Larrayoz M; Young E; Anagnostopoulos A; Smedby KE; Juliusson G; Sheehy O; Catherwood M; Strefford JC; Stavroyianni N; Belessi C; Pospisilova S; Oscier D; Gaidano G; Campo E; Haferlach C; Ghia P; Rosenquist R; Stamatopoulos K
Article: METHODS IN MOLECULAR BIOLOGY. 2019;1881:51-62
Immunoglobulin Gene Analysis in Chronic Lymphocytic Leukemia.
Agathangelidis A; Rosenquist R; Davi F; Ghia P; Belessi C; Hadzidimitriou A; Stamatopoulos K
Article: BLOOD CANCER JOURNAL. 2018;9(1):1
Genetic correlation between multiple myeloma and chronic lymphocytic leukaemia provides evidence for shared aetiology
Went M; Sud A; Speedy H; Sunter NJ; Foersti A; Law PJ; Johnson DC; Mirabella F; Holroyd A; Li N; Orlando G; Weinhold N; van Duin M; Chen B; Mitchell JS; Mansouri L; Juliusson G; Smedby KE; Jayne S; Majid A; Dearden C; Allsup DJ; Bailey JR; Pratt G; Pepper C; Fegan C; Rosenquist R; Kuiper R; Stephens OW; Bertsch U; Broderick P; Einsele H; Gregory WM; Hillengass J; Hoffmann P; Jackson GH; Joeckel K-H; Nickel J; Noethen MM; da Silva Filho MI; Thomsen H; Walker BA; Broyl A; Davies FE; Hansson M; Goldschmidt H; Dyer MJS; Kaiser M; Sonneveld P; Morgan GJ; Hemminki K; Nilsson B; Catovsky D; Allan JM; Houlston RS
Article: JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. 2018;(141)
Immunoglobulin Gene Sequence Analysis In Chronic Lymphocytic Leukemia: From Patient Material To Sequence Interpretation
Agathangelidis A; Sutton LA; Hadzidimitriou A; Tresoldi C; Langerak AW; Belessi C; Davi F; Rosenquist R; Stamatopoulos K; Ghia P
Article: BMC BIOINFORMATICS. 2018;19(Suppl 14):414
Automated shape-based clustering of 3D immunoglobulin protein structures in chronic lymphocytic leukemia
Polychronidou E; Kalamaras I; Agathangelidis A; Sutton L-A; Yan X-J; Bikos V; Vardi A; Mochament K; Chiorazzi N; Belessi C; Rosenquist R; Ghia P; Stamatopoulos K; Vlamos P; Chailyan A; Overby N; Marcatili P; Hatzidimitriou A; Tzovaras D
Article: SEMINARS IN CANCER BIOLOGY. 2018;51:1-11
Epigenetic deregulation in chronic lymphocytic leukemia: Clinical and biological impact
Mansouri L; Wierzbinska JA; Plass C; Rosenquist R
Article: ONCOTARGET. 2018;9(40):26019-26031
A novel ex vivo high-throughput assay reveals antiproliferative effects of idelalisib and ibrutinib in chronic lymphocytic leukemia.
Primo D; Scarfò L; Xochelli A; Mattsson M; Ranghetti P; Espinosa AB; Robles A; Gorrochategui J; Martínez-López J; de la Serna J; González M; Gil AC; Anguita E; Iraheta S; Munugalavadla V; Quéva C; Tannheimer S; Rosenquist R; Stamatopoulos K; Ballesteros J; Ghia P
Article: HAEMATOLOGICA. 2018;103(5):865-873
Highly similar genomic landscapes in monoclonal B-cell lymphocytosis and ultra-stable chronic lymphocytic leukemia with low frequency of driver mutations
Agathangelidis A; Ljungstrom V; Scarfo L; Fazi C; Gounari M; Pandzic T; Sutton L-A; Stamatopoulos K; Tonon G; Rosenquist R; Ghia P
Article: BLOOD ADVANCES. 2018;2(6):621-625
Clinical and functional impact of recurrent S1PR1 mutations in mantle cell lymphoma
Wasik AM; Wu C; Mansouri L; Rosenquist R; Pan-Hammarstrom Q; Sander B
Article: ACTA ONCOLOGICA. 2018;57(2):187-194
U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden
Glimelius B; Melin B; Enblad G; Alafuzoff I; Beskow A; Ahlstrom H; Bill-Axelson A; Birgisson H; Bjor O; Edqvist P-H; Hansson T; Helleday T; Hellman P; Henriksson K; Hesselager G; Hultdin M; Haggman M; Hoglund M; Jonsson H; Larsson C; Lindman H; Ljuslinder I; Mindus S; Nygren P; Ponten F; Riklund K; Rosenquist R; Sandin F; Schwenk JM; Stenling R; Stalberg K; Stalberg P; Sundstrom C; Karlsson CT; Westermark B; Bergh A; Claesson-Welsh L; Palmqvist R; Sjoblom T
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Drug-perturbation-based stratification of blood cancer
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Article: CYTOMETRY PART B-CLINICAL CYTOMETRY. 2018;94(1):121-128
Reproducible diagnosis of chronic lymphocytic leukemia by flow cytometry: An European Research Initiative on CLL (ERIC) & European Society for Clinical Cell Analysis (ESCCA) Harmonisation project.
Rawstron AC; Kreuzer K-A; Soosapilla A; Spacek M; Stehlikova O; Gambell P; McIver-Brown N; Villamor N; Psarra K; Arroz M; Milani R; de la Serna J; Cedena MT; Jaksic O; Nomdedeu J; Moreno C; Rigolin GM; Cuneo A; Johansen P; Johnsen HE; Rosenquist R; Niemann CU; Kern W; Westerman D; Trneny M; Mulligan S; Doubek M; Pospisilova S; Hillmen P; Oscier D; Hallek M; Ghia P; Montserrat E
Article: CLINICAL CANCER RESEARCH. 2017;23(17):5292-5301
Chronic Lymphocytic Leukemia with Mutated IGHV4-34 Receptors: Shared and Distinct Immunogenetic Features and Clinical Outcomes
Xochelli A; Baliakas P; Kavakiotis I; Agathangelidis A; Sutton L-A; Minga E; Ntoufa S; Tausch E; Yan X-J; Shanafelt T; Plevova K; Boudjogra M; Rossi D; Davis Z; Navarro A; Sandberg Y; Vojdeman FJ; Scarfo L; Stavroyianni N; Sudarikov A; Veronese S; Tzenou T; Karan-Djurasevic T; Catherwood M; Kienle D; Chatzouli M; Facco M; Bahlo J; Pott C; Pedersen LB; Mansouri L; Smedby KE; Chu CC; Giudicelli V; Lefranc M-P; Panagiotidis P; Juliusson G; Anagnostopoulos A; Vlahavas I; Antic D; Trentin L; Montillo M; Niemann C; Doehner H; Langerak AW; Pospisilova S; Hallek M; Campo E; Chiorazzi N; Maglaveras N; Oscier D; Gaidano G; Jelinek DF; Stilgenbauer S; Chouvarda I; Darzentas N; Belessi C; Davi F; Hadzidimitriou A; Rosenquist R; Ghia P; Stamatopoulos K
Article: LEUKEMIA. 2017;31(7):1547-1554
EGR2 mutations define a new clinically aggressive subgroup of chronic lymphocytic leukemia
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Article: AMERICAN JOURNAL OF PATHOLOGY. 2017;187(7):1454-1458
Numerous Ontogenetic Roads to Mantle Cell Lymphoma Immunogenetic and Immunohistochemical Evidence
Pouliou E; Xochelli A; Kanellis G; Stalika E; Sutton L-A; Navarro A; Agathangelidis A; Dimosthenous K; Anagnostopoulos A; Patsouris E; Korkolopoulou P; Sundstrom C; Ghia P; Ponzoni M; Sander B; Campo E; Rosenquist R; Hadzidimitriou A; Stamatopoulos K; Papadaki T
Article: AMERICAN JOURNAL OF EPIDEMIOLOGY. 2017;185(8):681-687
Possible Interaction Between Cigarette Smoking and HLA-DRB1 Variation in the Risk of Follicular Lymphoma
Baecklund F; Foo J-N; Askling J; Eloranta S; Glimelius I; Liu J; Hjalgrim H; Rosenquist R; Padyukov L; Smedby KE
Article: SCIENTIFIC REPORTS. 2017;7(1):623
Flow Cytometric Measurement of Blood Cells with BCR-ABL1 Fusion Protein in Chronic Myeloid Leukemia
Lof L; Arngarden L; Olsson-Stromberg U; Siart B; Jansson M; Dahlin JS; Thorn I; Christiansson L; Hermansson M; Larsson A; Ahlstrand E; Walinder G; Soderberg O; Rosenquist R; Landegren U; Kamali-Moghaddam M
Article: HAEMATOLOGICA. 2017;102(3):562-572
T cells in chronic lymphocytic leukemia display dysregulated expression of immune checkpoints and activation markers
Palma M; Gentilcore G; Heimersson K; Mozaffari F; Nasman-Glaser B; Young E; Rosenquist R; Hansson L; Osterborg A; Mellstedt H
Article: NATURE COMMUNICATIONS. 2017;8:14175
Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia
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Article: CLINICAL CANCER RESEARCH. 2016;22(24):6217-6227
Transposon Mutagenesis Reveals Fludarabine Resistance Mechanisms in Chronic Lymphocytic Leukemia
Pandzic T; Larsson J; He L; Kundu S; Ban K; Akhtar-Ali M; Hellstrom AR; Schuh A; Clifford R; Blakemore SJ; Strefford JC; Baumann T; Lopez-Guillermo A; Campo E; Ljungstrom V; Mansouri L; Rosenquist R; Sjoblom T; Hellstrom M
Article: BLOOD. 2016;128(23):2666-2670
Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma
Mansouri L; Noerenberg D; Young E; Mylonas E; Abdulla M; Frick M; Asmar F; Ljungstroem V; Schneider M; Yoshida K; Skaftason A; Pandzic T; Gonzalez B; Tasidou A; Waldhueter N; Rivas-Delgado A; Angelopoulou M; Ziepert M; Arends CM; Couronne L; Lenze D; Baldus CD; Bastard C; Okosun J; Fitzgibbon J; Doerken B; Drexler HG; Roos-Weil D; Schmitt CA; Munch-Petersen HD; Zenz T; Hansmann M-L; Strefford JC; Enblad G; Bernard OA; Ralfkiaer E; Erlanson M; Korkolopoulou P; Hultdin M; Papadaki T; Gronbaek K; Lopez-Guillermo A; Ogawa S; Kuppers R; Stamatopoulos K; Stavroyianni N; Kanellis G; Rosenwald A; Campo E; Amini R-M; Ott G; Vassilakopoulos TP; Hummel M; Rosenquist R; Damm F
Article: LEUKEMIA. 2016;30(11):2179-2186
Genomic disruption of the histone methyltransferase SETD2 in chronic lymphocytic leukaemia
Parker H; Rose-Zerilli MJJ; Larrayoz M; Clifford R; Edelmann J; Blakemore S; Gibson J; Wang J; Ljungstrom V; Wojdacz TK; Chaplin T; Roghanian A; Davis Z; Parker A; Tausch E; Ntoufa S; Ramos S; Robbe P; Alsolami R; Steele AJ; Packham G; Rodriguez-Vicente AE; Brown L; McNicholl F; Forconi F; Pettitt A; Hillmen P; Dyer M; Cragg MS; Chelala C; Oakes CC; Rosenquist R; Stamatopoulos K; Stilgenbauer S; Knight S; Schuh A; Oscier DG; Strefford JC
Article: NATURE COMMUNICATIONS. 2016;7:13182
Massive and parallel expression profiling using microarrayed single-cell sequencing
Vickovic S; Stahl PL; Salmen F; Giatrellis S; Westholm JO; Mollbrink A; Navarro JF; Custodio J; Bienko M; Sutton L-A; Rosenquist R; Frisen J; Lundeberg J
Article: HAEMATOLOGICA. 2016;101(8):959-967
Different spectra of recurrent gene mutations in subsets of chronic lymphocytic leukemia harboring stereotyped B-cell receptors
Sutton L-A; Young E; Baliakas P; Hadzidimitriou A; Moysiadis T; Plevova K; Rossi D; Kminkova J; Stalika E; Pedersen LB; Malcikova J; Agathangelidis A; Davis Z; Mansouri L; Scarfo L; Boudjoghra M; Navarro A; Muggen AF; Yan X-J; Nguyen-Khac F; Larrayoz M; Panagiotidis P; Chiorazzi N; Niemann CU; Belessi C; Campo E; Strefford JC; Langerak AW; Oscier D; Gaidano G; Pospisilova S; Davi F; Ghia P; Stamatopoulos K; Rosenquist R
Article: ONCOTARGET. 2016;7(25):38180-38190
Genetic heterogeneity in primary and relapsed mantle cell lymphomas: Impact of recurrent CARD11 mutations
Wu C; de Miranda NFCC; Chen L; Wasik AM; Mansouri L; Jurczak W; Galazka K; Dlugosz-Danecka M; Machaczka M; Zhang H; Peng R; Morin RD; Rosenquist R; Sander B; Pan-Hammarstrom Q
Article: ONCOTARGET. 2016;7(24):35946-35959
The histone methyltransferase EZH2 as a novel prosurvival factor in clinically aggressive chronic lymphocytic leukemia
Papakonstantinou N; Ntoufa S; Chartomatsidou E; Kotta K; Agathangelidis A; Giassafaki L; Karamanli T; Bele P; Moysiadis T; Baliakas P; Sutton LA; Stavroyianni N; Anagnostopoulos A; Makris AM; Ghia P; Rosenquist R; Stamatopoulos K
Article: EPIGENETICS. 2016;11(6):449-455
Prognostic impact of epigenetic classification in chronic lymphocytic leukemia: The case of subset #2
Bhoi S; Ljungstrom V; Baliakas P; Mattsson M; Smedby KE; Juliusson G; Rosenquist R; Mansouri L
Article: EPIGENETICS. 2016;11(5):335-343
Epigenetic silencing of miR-26A1 in chronic lymphocytic leukemia and mantle cell lymphoma: Impact on EZH2 expression
Kopparapu PK; Bhoi S; Mansouri L; Arabanian LS; Plevova K; Pospisilova S; Wasik AM; Croci GA; Sander B; Paulli M; Rosenquist R; Kanduri M
Article: CLINICAL CANCER RESEARCH. 2016;22(8):2032-2040
An Immunogenetic Signature of Ongoing Antigen Interactions in Splenic Marginal Zone Lymphoma Expressing IGHV1-2*04 Receptors
Bikos V; Karypidou M; Stalika E; Baliakas P; Xochelli A; Sutton L-A; Papadopoulos G; Agathangelidis A; Papadopoulou E; Davis Z; Algara P; Kanellis G; Traverse-Glehen A; Mollejo M; Anagnostopoulos A; Ponzoni M; Gonzalez D; Pospisilova S; Matutes E; Angel Piris M; Papadaki T; Ghia P; Rosenquist R; Oscier D; Darzentas N; Tzovaras D; Belessi C; Hadzidimitriou A; Stamatopoulos K
Article: BLOOD. 2016;127(8):1007-1016
Whole-exome sequencing in relapsing chronic lymphocytic leukemia: clinical impact of recurrent RPS15 mutations
Ljungstrom V; Cortese D; Young E; Pandzic T; Mansouri L; Plevova K; Ntoufa S; Baliakas P; Clifford R; Sutton L-A; Blakemore SJ; Stavroyianni N; Agathangelidis A; Rossi D; Hoglund M; Kotaskova J; Juliusson G; Belessi C; Chiorazzi N; Panagiotidis P; Langerak AW; Smedby KE; Oscier D; Gaidano G; Schuh A; Davi F; Pott C; Strefford JC; Trentin L; Pospisilova S; Ghia P; Stamatopoulos K; Sjoblom T; Rosenquist R
Article: CLINICAL CANCER RESEARCH. 2016;22(1):167-174
Antigen Selection Shapes the T-cell Repertoire in Chronic Lymphocytic Leukemia
Vardi A; Agathangelidis A; Stalika E; Karypidou M; Siorenta A; Anagnostopoulos A; Rosenquist R; Hadzidimitriou A; Ghia P; Sutton L-A; Stamatopoulos K
Journal article: SCIENCE. 2015;350(6266):1397
The impact of new technologies on clinical decision-making in health care
Rosenquist Brandell R; Kallioniemi O; Wedell A
Article: CLINICAL CANCER RESEARCH. 2015;21(18):4174-4183
Genetics and Prognostication in Splenic Marginal Zone Lymphoma: Revelations from Deep Sequencing
Parry M; Rose-Zerilli MJJ; Ljungstrom V; Gibson J; Wang J; Walewska R; Parker H; Parker A; Davis Z; Gardiner A; McIver-Brown N; Kalpadakis C; Xochelli A; Anagnostopoulos A; Fazi C; de Castro DG; Dearden C; Pratt G; Rosenquist R; Ashton-Key M; Forconi F; Collins A; Ghia P; Matutes E; Pangalis G; Stamatopoulos K; Oscier D; Strefford JC
Article: BLOOD. 2015;126(2):233-241
SF3B1 mutation identifies a distinct subset of myelodysplastic syndrome with ring sideroblasts
Malcovati L; Karimi M; Papaemmanuil E; Ambaglio I; Jadersten M; Jansson M; Elena C; Galli A; Walldin G; Della Porta MG; Raaschou-Jensen K; Travaglino E; Kallenbach K; Pietra D; Ljungstrom V; Conte S; Boveri E; Invernizzi R; Rosenquist R; Campbell PJ; Cazzola M; Lindberg EH
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2015;212(6):833-843
Functional loss of IκBε leads to NF-κB deregulation in aggressive chronic lymphocytic leukemia
Mansouri L; Sutton L-A; Ljungstrom V; Bondza S; Arngarden L; Bhoi S; Larsson J; Cortese D; Kalushkova A; Plevova K; Young E; Gunnarsson R; Falk-Sorqvist E; Lonn P; Muggen AF; Yan X-J; Sander B; Enblad G; Smedby KE; Juliusson G; Belessi C; Rung J; Chiorazzi N; Strefford JC; Langerak AW; Pospisilova S; Davi F; Hellstrom M; Jernberg-Wiklund H; Ghia P; Soderberg O; Stamatopoulos K; Nilsson M; Rosenquist R
Article: AMERICAN JOURNAL OF PATHOLOGY. 2015;185(6):1740-1748
Molecular Evidence for Antigen Drive in the Natural History of Mantle Cell Lymphoma
Xochelli A; Sutton L-A; Agathangelidis A; Stalika E; Karypidou M; Marantidou F; Navarro Lopez A; Papadopoulos G; Supikova J; Groenen P; Boudjogra M; Sundstrom C; Ponzoni M; Francova HS; Anagnostopoulos A; Pospisilova S; Papadaki T; Tzovaras D; Ghia P; Pott C; Davi F; Campo E; Rosenquist R; Hadzidimitriou A; Belessi C; Stamatopoulos K
Article: BREAST CANCER RESEARCH. 2015;17(1):61
An original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriers
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Article: MOLECULAR MEDICINE. 2015;20(1):720-728
An Entity Evolving into a Community: Defining the Common Ancestor and Evolutionary Trajectory of Chronic Lymphocytic Leukemia Stereotyped Subset #4
Sutton L-A; Papadopoulos G; Hadzidimitriou A; Papadopoulos S; Kostareli E; Rosenquist R; Tzovaras D; Stamatopoulos K
Article: HAEMATOLOGICA. 2015;100(3):370-376
Targeted next-generation sequencing in chronic lymphocytic leukemia: a high-throughput yet tailored approach will facilitate implementation in a clinical setting
Sutton L-A; Ljungstrom V; Mansouri L; Young E; Cortese D; Navrkalova V; Malcikova J; Muggen AF; Trbusek M; Panagiotidis P; Davi F; Belessi C; Langerak AW; Ghia P; Pospisilova S; Stamatopoulos K; Rosenquist R
Article: LEUKEMIA. 2015;29(2):329-336
Recurrent mutations refine prognosis in chronic lymphocytic leukemia
Baliakas P; Hadzidimitriou A; Sutton L-A; Rossi D; Minga E; Villamor N; Larrayoz M; Kminkova J; Agathangelidis A; Davis Z; Tausch E; Stalika E; Kantorova B; Mansouri L; Scarfo L; Cortese D; Navrkalova V; Rose-Zerilli MJJ; Smedby KE; Juliusson G; Anagnostopoulos A; Makris AM; Navarro A; Delgado J; Oscier D; Belessi C; Stilgenbauer S; Ghia P; Pospisilova S; Gaidano G; Campo E; Strefford JC; Stamatopoulos K; Rosenquist R
Article: BLOOD. 2015;125(5):856-859
Not all IGHV3-21 chronic lymphocytic leukemias are equal: prognostic considerations
Baliakas P; Agathangelidis A; Hadzidimitriou A; Sutton L-A; Minga E; Tsanousa A; Scarfo L; Davis Z; Yan X-J; Shanafelt T; Plevova K; Sandberg Y; Vojdeman FJ; Boudjogra M; Tzenou T; Chatzouli M; Chu CC; Veronese S; Gardiner A; Mansouri L; Smedby KE; Pedersen LB; Moreno D; Van Lom K; Giudicelli V; Francova HS; Nguyen-Khac F; Panagiotidis P; Juliusson G; Angelis L; Anagnostopoulos A; Lefranc M-P; Facco M; Trentin L; Catherwood M; Montillo M; Geisler CH; Langerak AW; Pospisilova S; Chiorazzi N; Oscier D; Jelinek DF; Darzentas N; Belessi C; Davi F; Ghia P; Rosenquist R; Stamatopoulos K
Article: IMMUNOGENETICS. 2015;67(1):61-66
Immunoglobulin heavy variable (IGHV) genes and alleles: new entities, new names and implications for research and prognostication in chronic lymphocytic leukaemia
Xochelli A; Agathangelidis A; Kavakiotis I; Minga E; Sutton LA; Baliakas P; Chouvarda I; Giudicelli V; Vlahavas I; Maglaveras N; Bonello L; Trentin L; Tedeschi A; Panagiotidis P; Geisler C; Langerak AW; Pospisilova S; Jelinek DF; Oscier D; Chiorazzi N; Darzentas N; Davi F; Ghia P; Rosenquist R; Hadzidimitriou A; Belessi C; Lefranc M-P; Stamatopoulos K
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2014;167(5):671-680
Impact of ABCB1 single nucleotide polymorphisms 1236C>T and 2677G>T on overall survival in FLT3 wild-type de novo AML patients with normal karyotype
Falk IJ; Fyrberg A; Paul E; Nahi H; Hermanson M; Rosenquist R; Hoglund M; Palmqvist L; Stockelberg D; Wei Y; Green H; Lotfi K
Article: LANCET HAEMATOLOGY. 2014;1(2):e74-e84
Clinical effect of stereotyped B-cell receptor immunoglobulins in chronic lymphocytic leukaemia: a retrospective multicentre study
Baliakas P; Hadzidimitriou A; Sutton L-A; Minga E; Agathangelidis A; Nichelatti M; Tsanousa A; Scarfo L; Davis Z; Yan X-J; Shanafelt T; Plevova K; Sandberg Y; Vojdeman FJ; Boudjogra M; Tzenou T; Chatzouli M; Chu CC; Veronese S; Gardiner A; Mansouri L; Smedby KE; Pedersen LB; van Lom K; Giudicelli V; Francova HS; Nguyen-Khac F; Panagiotidis P; Juliusson G; Angelis L; Anagnostopoulos A; Lefranc M-P; Facco M; Trentin L; Catherwood M; Montillo M; Geisler CH; Langerak AW; Pospisilova S; Chiorazzi N; Oscier D; Jelinek DF; Darzentas N; Belessi C; Davi F; Rosenquist R; Ghia P; Stamatopoulos K
Article: HAEMATOLOGICA. 2014;99(11):1722-1730
Silenced B-cell receptor response to autoantigen in a poor-prognostic subset of chronic lymphocytic leukemia
Bergh A-C; Evaldsson C; Pedersen LB; Geisler C; Stamatopoulos K; Rosenquist R; Rosen A
Article: BMC MEDICAL GENETICS. 2014;15:113
A comprehensive evaluation of the role of genetic variation in follicular lymphoma survival
Baecklund F; Foo J-N; Bracci P; Darabi H; Karlsson R; Hjalgrim H; Rosenquist R; Adami H-O; Glimelius B; Melbye M; Conde L; Liu J; Humphreys K; Skibola CF; Smedby KE
Article: HAEMATOLOGICA. 2014;99(8):1285-1291
MDM2 promotor polymorphism and disease characteristics in chronic lymphocytic leukemia: results of an individual patient data-based meta-analysis
Benner A; Mansouri L; Rossi D; Majid A; Willander K; Parker A; Bond G; Pavlova S; Nueckel H; Merkel O; Ghia P; Montserrat E; Kaderi MA; Rosenquist R; Gaidano G; Dyer MJS; Soederkvist P; Linderholm M; Oscier D; Tvaruzkova Z; Pospisilova S; Duehrsen U; Greil R; Doehner H; Stilgenbauer S; Zenz T
Article: EPIGENETICS. 2014;9(6):910-917
microRNA-34b/c on chromosome 11q23 is aberrantly methylated in chronic lymphocytic leukemia
Deneberg S; Kanduri M; Ali D; Bengtzen S; Karimi M; Qu Y; Kimby E; Mansouri L; Rosenquist R; Lennartsson A; Lehmann S
Article: LEUKEMIA RESEARCH. 2014;38(6):682-690
Identification of B-cell lymphoma subsets by plasma protein profiling using recombinant antibody microarrays
Pauly F; Smedby KE; Jerkeman M; Hjalgrim H; Ohlsson M; Rosenquist R; Borrebaeck CAK; Wingren C
Article: CLINICAL CANCER RESEARCH. 2014;20(2):323-330
IgG-Switched CLL Has a Distinct Immunogenetic Signature from the Common MD Variant: Ontogenetic Implications
Vardi A; Agathangelidis A; Sutton L-A; Chatzouli M; Scarfo L; Mansouri L; Douka V; Anagnostopoulos A; Darzentas N; Rosenquist R; Ghia P; Belessi C; Stamatopoulos K
Article: NATURE GENETICS. 2014;46(1):56-60
A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia
Speedy HE; Di Bernardo MC; Sava GP; Dyer MJS; Holroyd A; Wang Y; Sunter NJ; Mansouri L; Juliusson G; Smedby KE; Roos G; Jayne S; Majid A; Dearden C; Hall AG; Mainou-Fowler T; Jackson GH; Summerfield G; Harris RJ; Pettitt AR; Allsup DJ; Bailey JR; Pratt G; Pepper C; Fegan C; Rosenquist R; Catovsky D; Allan JM; Houlston RS
Article: EPIGENETICS. 2013;8(12):1280-1288
A key role for EZH2 in epigenetic silencing of HOX genes in mantle cell lymphoma
Kanduri M; Sander B; Ntoufa S; Papakonstantinou N; Sutton L; Stamatopoulos K; Kanduri C; Rosenquist R
Article: AMERICAN JOURNAL OF HEMATOLOGY. 2013;88(12):1001-1006
Decreased survival in normal karyotype AML with single-nucleotide polymorphisms in genes encoding the AraC metabolizing enzymes cytidine deaminase and 5′-nucleotidase
Falk IJ; Fyrberg A; Paul E; Nahi H; Hermanson M; Rosenquist R; Hoglund M; Palmqvist L; Stockelberg D; Wei Y; Green H; Lotfi K
Article: LEUKEMIA. 2013;27(11):2196-2199
Distinct patterns of novel gene mutations in poor-prognostic stereotyped subsets of chronic lymphocytic leukemia: the case of SF3B1 and subset #2
Strefford JC; Sutton L-A; Baliakas P; Agathangelidis A; Malcikova J; Plevova K; Scarfo L; Davis Z; Stalika E; Cortese D; Cahill N; Pedersen LB; di Celle PF; Tzenou T; Geisler C; Panagiotidis P; Langerak AW; Chiorazzi N; Pospisilova S; Oscier D; Davi F; Belessi C; Mansouri L; Ghia P; Stamatopoulos K; Rosenquist R
Article: BLOOD. 2013;122(15):2673-2682
Two main genetic pathways lead to the transformation of chronic lymphocytic leukemia to Richter syndrome
Chigrinova E; Rinaldi A; Kwee I; Rossi D; Rancoita PMV; Strefford JC; Oscier D; Stamatopoulos K; Papadaki T; Berger F; Young KH; Murray F; Rosenquist R; Greiner TC; Chan WC; Orlandi EM; Lucioni M; Marasca R; Inghirami G; Ladetto M; Forconi F; Cogliatti S; Votavova H; Swerdlow SH; Stilgenbauer S; Piris MA; Matolcsy A; Spagnolo D; Nikitin E; Zamo A; Gattei V; Bhagat G; Ott G; Zucca E; Gaidano G; Bertoni F
Article: MOLECULAR MEDICINE. 2013;19(1):230-236
Temporal Dynamics of Clonal Evolution in Chronic Lymphocytic Leukemia with Stereotyped IGHV4-34/IGKV2-30 Antigen Receptors: Longitudinal Immunogenetic Evidence
Sutton L-A; Kostareli E; Stalika E; Tsaftaris A; Anagnostopoulos A; Darzentas N; Rosenquist R; Stamatopoulos K
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2013;210(9):1729-1742
DNA repair genes are selectively mutated in diffuse large B cell lymphomas
de Miranda NFCC; Peng R; Georgiou K; Wu C; Sorqvist EF; Berglund M; Chen L; Gao Z; Lagerstedt K; Lisboa S; Roos F; van Wezel T; Teixeira MR; Rosenquist R; Sundstrom C; Enblad G; Nilsson M; Zeng Y; Kipling D; Pan-Hammarstrom Q
Article: AMERICAN JOURNAL OF HEMATOLOGY. 2013;88(8):647-651
Short telomere length is associated with NOTCH1/SF3B1/TP53 aberrations and poor outcome in newly diagnosed chronic lymphocytic leukemia patients
Mansouri L; Grabowski P; Degerman S; Svenson U; Gunnarsson R; Cahill N; Smedby KE; Geisler C; Juliusson G; Roos G; Rosenquist R
Article: LEUKEMIA & LYMPHOMA. 2013;54(8):1769-1779
Molecular characterization of neoplastic and normal "sister" lymphoblastoid B-cell lines from chronic lymphocytic leukemia
Myhrinder AL; Hellqvist E; Bergh A-C; Jansson M; Nilsson K; Hultman P; Jonasson J; Buhl AM; Pedersen LB; Jurlander J; Klein E; Weit N; Herling M; Rosenquist R; Rosen A
Article: EPIGENETICS. 2013;8(7):720-729
ANGPT2 promoter methylation is strongly associated with gene expression and prognosis in chronic lymphocytic leukemia
Martinelli S; Kanduri M; Maffei R; Fiorcari S; Bulgarelli J; Marasca R; Rosenquist R
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2013;162(2):221-228
rs2072135, a low-penetrance variant for chronic lymphocytic leukaemia?
Sava GP; Speedy HE; Di Bernardo MC; Deaglio S; Karabon L; Frydecka I; Woszczyk D; Rossi D; Gaidano G; Mansouri L; Smedby KE; Juliusson G; Rosenquist R; Catovsky D; Houlston RS
Article: PLOS GENETICS. 2013;9(3):e1003212
Genome-Wide Association Study in BRCA1 Mutation Carriers Identifies Novel Loci Associated with Breast and Ovarian Cancer Risk
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Article: LEUKEMIA. 2013;27(1):150-158
450K-array analysis of chronic lymphocytic leukemia cells reveals global DNA methylation to be relatively stable over time and similar in resting and proliferative compartments
Cahill N; Bergh A-C; Kanduri M; Goransson-Kultima H; Mansouri L; Isaksson A; Ryan F; Smedby KE; Juliusson G; Sundstrom C; Rosen A; Rosenquist R
Article: EPIGENETICS. 2012;7(12):1435-1442
Distinct transcriptional control in major immunogenetic subsets of chronic lymphocytic leukemia exhibiting subset-biased global DNA methylation profiles
Kanduri M; Marincevic M; Halldorsdottir AM; Mansouri L; Junevik K; Ntoufa S; Kultima HG; Isaksson A; Juliusson G; Andersson P-O; Ehrencrona H; Stamatopoulos K; Rosenquist R
Article: ANTICANCER RESEARCH. 2012;32(8):3125-3136
Screening for Cytotoxic Compounds in Poor-prognostic Chronic Lymphocytic Leukemia
Norberg M; Lindhagen E; Kanduri M; Rickardson L; Sundstrom C; Stamatopoulos K; Rosenquist R; Aleskog A
Article: JOURNAL OF GENETIC COUNSELING. 2012;21(4):510-526
What Information Do Cancer Genetic Counselees Prioritize?
Roshanai AH; Lampic C; Ingvoldstad C; Askmalm MS; Bjorvatn C; Rosenquist R; Nordin K
Article: AMERICAN JOURNAL OF HEMATOLOGY. 2012;87(7):737-740
Next generation RNA-sequencing in prognostic subsets of chronic lymphocytic leukemia
Mansouri L; Gunnarsson R; Sutton L-A; Ameur A; Hooper SD; Mayrhofer M; Juliusson G; Isaksson A; Gyllensten U; Rosenquist R
Article: BRITISH JOURNAL OF CANCER. 2012;106(12):2016-2024
Association of PHB 1630 C>T and MTHFR 677 C>T polymorphisms with breast and ovarian cancer risk in BRCA1/2 mutation carriers: results from a multicenter study
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Article: CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2012;12(3):201-206
IGHV3-21 Gene Frequency in a Swedish Cohort of Patients With Newly Diagnosed Chronic Lymphocytic Leukemia
Cahill N; Sutton L-A; Jansson M; Murray F; Mansouri L; Gunnarsson R; Ryan F; Smedby KE; Geisler C; Juliusson G; Rosenquist R
Article: BLOOD. 2012;119(19):4467-4475
Stereotyped B-cell receptors in one-third of chronic lymphocytic leukemia: a molecular classification with implications for targeted therapies
Agathangelidis A; Darzentas N; Hadzidimitriou A; Brochet X; Murray F; Yan X-J; Davis Z; van Gastel-Mol EJ; Tresoldi C; Chu CC; Cahill N; Giudicelli V; Tichy B; Pedersen LB; Foroni L; Bonello L; Janus A; Smedby K; Anagnostopoulos A; Merle-Beral H; Laoutaris N; Juliusson G; di Celle PF; Pospisilova S; Jurlander J; Geisler C; Tsaftaris A; Lefranc M-P; Langerak AW; Oscier DG; Chiorazzi N; Belessi C; Davi F; Rosenquist R; Ghia P; Stamatopoulos K
Article: AMERICAN JOURNAL OF HEMATOLOGY. 2012;87(4):361-367
Mantle cell lymphoma displays a homogenous methylation profile: A comparative analysis with chronic lymphocytic leukemia
Halldorsdottir AM; Kanduri M; Marincevic M; Mansouri L; Isaksson A; Goransson H; Axelsson T; Agarwal P; Jernberg-Wiklund H; Stamatopoulos K; Sander B; Ehrencrona H; Rosenquist R
Article: PHARMACOGENOMICS JOURNAL. 2012;12(2):111-118
Association of ABCB1 polymorphisms with survival and in vitro cytotoxicty in de novo acute myeloid leukemia with normal karyotype
Green H; Falk IJ; Lotfi K; Paul E; Hermansson M; Rosenquist R; Paul C; Nahi H
Article: BREAST CANCER RESEARCH. 2012;14(1):R33
Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers
Antoniou AC; Kuchenbaecker KB; Soucy P; Beesley J; Chen X; McGuffog L; Lee A; Barrowdale D; Healey S; Sinilnikova OM; Caligo MA; Loman N; Harbst K; Lindblom A; Arver B; Rosenquist R; Karlsson P; Nathanson K; Domchek S; Rebbeck T; Jakubowska A; Lubinski J; Jaworska K; Durda K; Zlowowcka-Perlowska E; Osorio A; Duran M; Andres R; Benitez J; Hamann U; Hogervorst FB; van Os TA; Verhoef S; Meijers-Heijboer HEJ; Wijnen J; Garcia EBG; Ligtenberg MJ; Kriege M; Collee M; Ausems MGEM; Oosterwijk JC; Peock S; Frost D; Ellis SD; Platte R; Fineberg E; Evans DG; Lalloo F; Jacobs C; Eeles R; Adlard J; Davidson R; Cole T; Cook J; Paterson J; Douglas F; Brewer C; Hodgson S; Morrison PJ; Walker L; Rogers MT; Donaldson A; Dorkins H; Godwin AK; Bove B; Stoppa-Lyonnet D; Houdayer C; Buecher B; de Pauw A; Mazoyer S; Calender A; Leone M; Bressac-de Paillerets B; Caron O; Sobol H; Frenay M; Prieur F; Ferrer SF; Mortemousque I; Buys S; Daly M; Miron A; Terry MB; Hopper JL; John EM; Southey M; Goldgar D; Singer CF; Fink-Retter A; Tea M-K; Kaulich DG; Hansen TVO; Nielsen FC; Barkardottir RB; Gaudet M; Kirchhoff T; Joseph V; Dutra-Clarke A; Offit K; Piedmonte M; Kirk J; Cohn D; Hurteau J; Byron J; Fiorica J; Toland AE; Montagna M; Oliani C; Imyanitov E; Isaacs C; Tihomirova L; Blanco I; Lazaro C; Teule A; Del Valle J; Gayther SA; Odunsi K; Gross J; Karlan BY; Olah E; Teo S-H; Ganz PA; Beattie MS; Dorfling CM; van Rensburg EJ; Diez O; Kwong A; Schmutzler RK; Wappenschmidt B; Engel C; Meindl A; Ditsch N; Arnold N; Heidemann S; Niederacher D; Preisler-Adams S; Gadzicki D; Varon-Mateeva R; Deissler H; Gehrig A; Sutter C; Kast K; Fiebig B; Schaefer D; Caldes T; de la Hoya M; Nevanlinna H; Muranen TA; Lesperance B; Spurdle AB; Neuhausen SL; Ding YC; Wang X; Fredericksen Z; Pankratz VS; Lindor NM; Peterlongo P; Manoukian S; Peissel B; Zaffaroni D; Bonanni B; Bernard L; Dolcetti R; Papi L; Ottini L; Radice P; Greene MH; Loud JT; Andrulis IL; Ozcelik H; Mulligan AM; Glendon G; Thomassen M; Gerdes A-M; Jensen UB; Skytte A-B; Kruse TA; Chenevix-Trench G; Couch FJ; Simard J; Easton DF
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2012;209(2):291-305
Cernunnos influences human immunoglobulin class switch recombination and may be associated with B cell lymphomagenesis
Du L; Peng R; Bjorkman A; de Miranda NF; Rosner C; Kotnis A; Berglund M; Liu C; Rosenquist R; Enblad G; Sundstrom C; Hojjat-Farsangi M; Rabbani H; Teixeira MR; Revy P; Durandy A; Zeng Y; Gennery AR; de Villartay J-P; Pan-Hammarstrom Q
Article: ONCOIMMUNOLOGY. 2012;1(1):18-27
Lymphoblastoid cell line with B1 cell characteristics established from a chronic lymphocytic leukemia clone by in vitro EBV infection
Rosen A; Bergh A-C; Gogolak P; Evaldsson C; Myhrinder AL; Hellqvist E; Rasul A; Bjorkholm M; Jansson M; Mansouri L; Liu A; Teh BT; Rosenquist R; Klein E
Article: BLOOD. 2011;118(22):5905-5913
Presence of FLT3-ITD and high BAALC expression are independent prognostic markers in childhood acute myeloid leukemia
Staffas A; Kanduri M; Hovland R; Rosenquist R; Ommen HB; Abrahamsson J; Forestier E; Jahnukainen K; Jonsson OG; Zeller B; Palle J; Lonnerholm G; Hasle H; Palmqvist L; Ehrencrona H
Article: BLOOD. 2011;118(11):3088-3095
Is there a role for antigen selection in mantle cell lymphoma? Immunogenetic support from a series of 807 cases
Hadzidimitriou A; Agathangelidis A; Darzentas N; Murray F; Delfau-Larue M-H; Pedersen LB; Navarro Lopez A; Dagklis A; Rombout P; Beldjord K; Kolstad A; Dreyling MH; Anagnostopoulos A; Tsaftaris A; Mavragani-Tsipidou P; Rosenwald A; Ponzoni M; Groenen P; Ghia P; Sander B; Papadaki T; Campo E; Geisler C; Rosenquist R; Davi F; Pott C; Stamatopoulos K
Article: HAEMATOLOGICA. 2011;96(8):1161-1169
Array-based genomic screening at diagnosis and during follow-up in chronic lymphocytic leukemia
Gunnarsson R; Mansouri L; Isaksson A; Goransson H; Cahill N; Jansson M; Rasmussen M; Lundin J; Norin S; Buhl AM; Smedby KE; Hjalgrim H; Karlsson K; Jurlander J; Geisler C; Juliusson G; Rosenquist R
Article: HAEMATOLOGICA. 2011;96(8):1153-1160
LPL is the strongest prognostic factor in a comparative analysis of RNA-based markers in early chronic lymphocytic leukemia
Kaderi MA; Kanduri M; Buhl AM; Sevov M; Cahill N; Gunnarsson R; Jansson M; Smedby KE; Hjalgrim H; Jurlander J; Juliusson G; Mansouri L; Rosenquist R
Article: LEUKEMIA. 2011;25(6):979-984
Immunoglobulin sequence analysis and prognostication in CLL: guidelines from the ERIC review board for reliable interpretation of problematic cases
Langerak AW; Davi F; Ghia P; Hadzidimitriou A; Murray F; Potter KN; Rosenquist R; Stamatopoulos K; Belessi C
Article: LEUKEMIA RESEARCH. 2011;35(4):438-443
Quantitative evaluation of p16^INK4a promoter methylation using pyrosequencing in de novo diffuse large B-cell lymphoma
Zainuddin N; Kanduri M; Berglund M; Lindell M; Amini R-M; Roos G; Sundstrom C; Enblad G; Rosenquist R
Article: BLOOD CANCER JOURNAL. 2011;1(3):e12
The novel NF-κB inhibitor IMD-0354 induces apoptosis in chronic lymphocytic leukemia
Kanduri M; Tobin G; Aleskog A; Nilsson K; Rosenquist R
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2011;152(6):743-753
Minimal residual disease assessment in childhood acute lymphoblastic leukaemia: a Swedish multi-centre study comparing real-time polymerase chain reaction and multicolour flow cytometry
Thorn I; Forestier E; Botling J; Thuresson B; Wasslavik C; Bjorklund E; Li A; Lindstrom-Eriksson E; Malec M; Gronlund E; Torikka K; Heldrup J; Abrahamsson J; Behrendtz M; Soderhall S; Jacobsson S; Olofsson T; Porwit A; Lonnerholm G; Rosenquist R; Sundstrom C
Article: LEUKEMIA RESEARCH. 2011;35(2):272-274
TP53 Mutations are infrequent in newly diagnosed chronic lymphocytic leukemia
Zainuddin N; Murray F; Kanduri M; Gunnarsson R; Smedby KE; Enblad G; Jurlander J; Juliusson G; Rosenquist R
Article: GENES CHROMOSOMES & CANCER. 2011;50(2):113-121
High-Resolution Genomic Screening in Mantle Cell Lymphoma-Specific Changes Correlate with Genomic Complexity, the Proliferation Signature and Survival
Halldorsdottir AM; Sander B; Goransson H; Isaksson A; Kimby E; Mansouri M; Rosenquist R; Ehrencrona H
Article: HAEMATOLOGICA. 2010;95(12):2072-2079
Distinct gene expression profiles in subsets of chronic lymphocytic leukemia expressing stereotyped IGHV4-34 B-cell receptors
Marincevic M; Mansouri M; Kanduri M; Isaksson A; Goransson H; Smedby KE; Jurlander J; Juliusson G; Davi F; Stamatopoulos K; Rosenquist R
Article: FAMILIAL CANCER. 2010;9(4):669-679
Disclosing cancer genetic information within families: perspectives of counselees and their at-risk relatives
Roshanai AH; Lampic C; Rosenquist R; Nordin K
Article: HAEMATOLOGICA. 2010;95(9):1519-1525
High-density screening reveals a different spectrum of genomic aberrations in chronic lymphocytic leukemia patients with 'stereotyped' IGHV3-21 and IGHV4-34 B-cell receptors
Marincevic M; Cahill N; Gunnarsson R; Isaksson A; Mansouri M; Goransson H; Rasmussen M; Jansson M; Ryan F; Karlsson K; Adami H-O; Davi F; Jurlander J; Juliusson G; Stamatopoulos K; Rosenquist R
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2010;150(4):473-479
Verification that common variation at 2q37.1, 6p25.3, 11q24.1, 15q23, and 19q13.32 influences chronic lymphocytic leukaemia risk
Crowther-Swanepoel D; Mansouri M; Enjuanes A; Vega A; Smedby KE; Ruiz-Ponte C; Jurlander J; Juliusson G; Montserrat E; Catovsky D; Campo E; Carracedo A; Rosenquist R; Houlston RS
Article: LEUKEMIA. 2010;24(7):1317-1324
Intraclonal diversification of immunoglobulin light chains in a subset of chronic lymphocytic leukemia alludes to antigen-driven clonal evolution
Kostareli E; Sutton L-A; Hadzidimitriou A; Darzentas N; Kouvatsi A; Tsaftaris A; Anagnostopoulos A; Rosenquist R; Stamatopoulos K
Article: AMERICAN JOURNAL OF HEMATOLOGY. 2010;85(6):418-425
Identification of uniquely expressed transcription factors in highly purified B-cell lymphoma samples
Andreasson U; Eden P; Peterson C; Hogerkorp C-M; Jerkeman M; Andersen N; Berglund M; Sundstrom C; Rosenquist R; Borrebaeck CAK; Ek S
Article: LEUKEMIA. 2010;24(5):924-931
Relapsed childhood high hyperdiploid acute lymphoblastic leukemia: presence of preleukemic ancestral clones and the secondary nature of microdeletions and RTK-RAS mutations
Davidsson J; Paulsson K; Lindgren D; Lilljebjorn H; Chaplin T; Forestier E; Andersen MK; Nordgren A; Rosenquist R; Fioretos T; Young BD; Johansson B
Article: ANNALS OF THE RHEUMATIC DISEASES. 2010;69(4):654-659
Rheumatoid arthritis, treatment with corticosteroids and risk of malignant lymphomas: results from a case-control study
Hellgren K; Iliadou A; Rosenquist R; Feltelius N; Backlin C; Enblad G; Askling J; Baecklund E
Article: LEUKEMIA RESEARCH. 2010;34(3):301-306
Lipoprotein lipase is differentially expressed in prognostic subsets of chronic lymphocytic leukemia but displays invariably low catalytical activity
Mansouri M; Sevov M; Fahlgren E; Tobin G; Jondal M; Osorio L; Roos G; Olivecrona G; Rosenquist R
Article: LEUKEMIA RESEARCH. 2010;34(3):335-339
Lack of association between the MDM2 promoter polymorphism SNP309 and clinical outcome in chronic lymphocytic leukemia
Kaderi MA; Mansouri M; Zainuddin N; Cahill N; Gunnarsson R; Jansson M; Kimby E; Aleskog A; Lundin J; Glimelius B; Melbye M; Juliusson G; Jurlander J; Rosenquist R
Article: NATURE GENETICS. 2010;42(2):132-136
Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk
Crowther-Swanepoel D; Broderick P; Di Bernardo MC; Dobbins SE; Torres M; Mansouri M; Ruiz-Ponte C; Enjuanes A; Rosenquist R; Carracedo A; Jurlander J; Campo E; Juliusson G; Montserrat E; Smedby KE; Dyer MJS; Matutes E; Dearden C; Sunter NJ; Hall AG; Mainou-Fowler T; Jackson GH; Summerfield G; Harris RJ; Pettitt AR; Allsup DJ; Bailey JR; Pratt G; Pepper C; Fegan C; Parker A; Oscier D; Allan JM; Catovsky D; Houlston RS
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2010;84(2):117-127
Applicability of IG/TCR gene rearrangements as targets for minimal residual disease assessment in a population-based cohort of Swedish childhood acute lymphoblastic leukaemia diagnosed 2002-2006
Thorn I; Forestier E; Thuresson B; Wasslavik C; Malec M; Li A; Lindstrom-Eriksson E; Botling J; Barbany G; Jacobsson S; Olofsson T; Porwit A; Sundstrom C; Rosenquist R
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2010;84(2):109-116
IGHV3-21 gene usage is associated with high TCL1 expression in chronic lymphocytic leukemia
Mansouri MR; Sevov M; Aleskog A; Jondal M; Merup M; Sundstrom C; Osorio L; Rosenquist R
Article: BLOOD. 2010;115(2):296-305
Differential genome-wide array-based methylation profiles in prognostic subsets of chronic lymphocytic leukemia
Kanduri M; Cahill N; Goransson H; Enstrom C; Ryan F; Isaksson A; Rosenquist R
Article: LEUKEMIA. 2010;24(1):125-132
A different ontogenesis for chronic lymphocytic leukemia cases carrying stereotyped antigen receptors: molecular and computational evidence
Darzentas N; Hadzidimitriou A; Murray F; Hatzi K; Josefsson P; Laoutaris N; Moreno C; Anagnostopoulos A; Jurlander J; Tsaftaris A; Chiorazzi N; Belessi C; Ghia P; Rosenquist R; Davi F; Stamatopoulos K
Article: AMERICAN JOURNAL OF HEMATOLOGY. 2009;84(12):803-808
Identification of molecular targets associated with transformed diffuse large B cell lymphoma using highly purified tumor cells
Andreasson U; Dictor M; Jerkeman M; Berglund M; Sundstrom C; Linderoth J; Rosenquist R; Borrebaeck CAK; Ek S
Article: BLOOD. 2009;114(20):4460-4468
Extensive intraclonal diversification in a subgroup of chronic lymphocytic leukemia patients with stereotyped IGHV4-34 receptors: implications for ongoing interactions with antigen
Sutton L-A; Kostareli E; Hadzidimitriou A; Darzentas N; Tsaftaris A; Anagnostopoulos A; Rosenquist R; Stamatopoulos K
Article: LEUKEMIA & LYMPHOMA. 2009;50(9):1528-1534
Genome-wide microarray-based comparative genomic hybridization analysis of lymphoplasmacytic lymphomas reveals heterogeneous aberrations
Buckley PG; Walsh SH; Laurell A; Sundstrom C; Roos G; Langford CF; Dumanski JP; Rosenquist R
Article: LEUKEMIA & LYMPHOMA. 2009;50(9):1512-1518
Low p14ARF expression in de novo acute myeloid leukemia with normal karyotype is associated with poor survival
Paul E; Uggla B; Deneberg S; Bengtzen S; Hermansson M; Dahlman I; Rosenquist R; Wiman KG; Nahi H
Article: LEUKEMIA RESEARCH. 2009;33(8):1047-1054
Monitoring minimal residual disease with flow cytometry, antigen-receptor gene rearrangements and fusion transcript quantification in Philadelphia-positive childhood acute lymphoblastic leukemia
Thorn I; Botling J; Hermansson M; Lonnerholm G; Sundstrom C; Rosenquist R; Barbany G
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2009;83(1):22-34
In vitro activity of 20 agents in different prognostic subgroups of chronic lymphocytic leukemia - rolipram and prednisolone active in cells from patients with poor prognosis
Lindhagen E; Norberg M; Kanduri M; Tobin G; Saisanen L; Aberg M; Gustafsson MG; Sundstrom C; Rosenquist R; Aleskog A
Article: PLOS ONE. 2009;4(6):e6057
Quantification of Normal Cell Fraction and Copy Number Neutral LOH in Clinical Lung Cancer Samples Using SNP Array Data
Goransson H; Edlund K; Rydaker M; Rasmussen M; Winquist J; Ekman S; Bergqvist M; Thomas A; Lambe M; Rosenquist R; Holmberg L; Micke P; Botling J; Isaksson A
Article: JOURNAL OF GENETIC COUNSELING. 2009;18(2):185-194
Cancer Genetic Counselees' Self-Reported Psychological Distress, Changes in Life, and Adherence to Recommended Surveillance Programs 3-7 Years Post Counseling
Roshanai AH; Rosenquist R; Lampic C; Nordin K
Article: MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS. 2009;660(1-2):1-11
Analysis of a set of missense, frameshift, and in-frame deletion variants of BRCA1
Carvalho M; Pino MA; Karchin R; Beddor J; Godinho-Netto M; Mesquita RD; Rodarte RS; Vaz DC; Monteiro VA; Manoukian S; Colombo M; Ripamonti CB; Rosenquist R; Suthers G; Borg A; Radice P; Grist SA; Monteiro ANA; Billack B
Article: BLOOD. 2009;113(2):403-411
Evidence for the significant role of immunoglobulin light chains in antigen recognition and selection in chronic lymphocytic leukemia
Hadzidimitriou A; Darzentas N; Murray F; Smilevska T; Arvaniti E; Tresoldi C; Tsaftaris A; Laoutaris N; Anagnostopoulos A; Davi F; Ghia P; Rosenquist R; Stamatopoulos K; Belessi C
Article: LEUKEMIA RESEARCH. 2009;33(1):60-66
TP53 mutations predict for poor survival in de novo diffuse large B-cell lymphoma of germinal center subtype
Zainuddin N; Berglund M; Wanders A; Ren Z-P; Amini R-M; Lindell M; Kanduri M; Roos G; Rosenquist R; Enblad G
Article: ACTA ONCOLOGICA. 2009;48(7):999-1009
Does enhanced information at cancer genetic counseling improve counselees' knowledge, risk perception, satisfaction and negotiation of information to at-risk relatives? - a randomized study
Roshanai AH; Rosenquist R; Lampic C; Nordin K
Article: LEUKEMIA & LYMPHOMA. 2008;49(12):2333-2343
Rapamycin shows anticancer activity in primary chronic lymphocytic leukemia cells in vitro, as single agent and in drug combination
Aleskog A; Norberg M; Nygren P; Rickardson L; Kanduri M; Tobin G; Aberg M; Gustafsson MG; Rosenquist R; Lindhagen E
Article: BMC BIOINFORMATICS. 2008;9:409
Normalization of Illumina Infinium whole-genome SNP data improves copy number estimates and allelic intensity ratios
Staaf J; Vallon-Christersson J; Lindgren D; Juliusson G; Rosenquist R; Hoglund M; Borg A; Ringner M
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2008;81(3):218-225
U-2973, a novel B-cell line established from a patient with a mature B-cell leukemia displaying concurrent t(14;18) and MYC translocation to a non-IG gene partner
Bostrom H; Leuchowius K-J; Hallbook H; Nordgren A; Thorn I; Thorselius M; Rosenquist R; Soderberg O; Sundstrom C
Article: GENES CHROMOSOMES & CANCER. 2008;47(8):697-711
Screening for copy-number alterations and loss of heterozygosity in chronic lymphocytic leukemia -: A comparative study of four differently designed, high resolution Microarray platforms
Gunnarsson R; Staaf J; Jansson M; Ottesen AM; Goransson H; Liljedahl U; Ralfkiaer U; Mansouri M; Buhl AM; Smedby KE; Hialgrim H; Syvanen A-C; Borg A; Isaksson A; Jurlander J; Juliusson G; Rosenquist R
Article: CANCER LETTERS. 2008;265(1):98-106
Phenotypic protein profiling of different B cell sub-populations using antibody CD-microarrays
Ellmark P; Hogerkorp CM; Ek S; Belov L; Berglund M; Rosenquist R; Christopherson RI; Borrebaeck CAK
Article: BLOOD. 2008;111(7):3838-3848
A new perspective:: molecular motifs on oxidized LDL, apoptotic cells, and bacteria are targets for chronic lymphocytic leukemia antibodies
Myhrinder AL; Hellqvist E; Sidorova E; Soederberg A; Baxendale H; Dahle C; Willander K; Tobin G; Baeckman E; Soederberg O; Rosenquist R; Hoerkkoe S; Rosen A
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2008;141(1):69-72
Expression of the human germinal-centre-associated lymphoma protein in diffuse large B-cell lymphomas in patients with rheumatoid arthritis
Baecklund E; Natkunam Y; Backlin C; Iliadou A; Askling J; Ekbom A; Feltelius N; Klareskog L; Enblad G; Lossos IS; Levy R; Sundstroem C; Rosenquist R
Article: LEUKEMIA & LYMPHOMA. 2008;49(3):477-487
Characterization of 6q deletions in mature B cell lymphomas and childhood acute lymphoblastic leukemia
Thelander EF; Ichimura K; Corcoran M; Barbany G; Nordgren A; Heyman M; Berglund M; Mungall A; Rosenquist R; Collins VP; Grander D; Larsson C; Lagercrantz S
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2008;140(6):665-672
Outcome of ETV6/RUNX1-positive childhood acute lymphoblastic leukaemia in the NOPHO-ALL-1992 protocol:: frequent late relapses but good overall survival
Forestier E; Heyman M; Andersen MK; Autio K; Blennow E; Borgstrom G; Golovleva I; Heim S; Heinonen K; Hovland R; Johannsson JH; Kerndrup G; Nordgren A; Rosenquist R; Swolin B; Johansson B
Article: BLOOD. 2008;111(4):2246-2252
Short telomeres are associated with genetic complexity, high-risk genomic aberrations, and short survival in chronic lymphocytic leukemia
Roos G; Kroeber A; Grabowski P; Kienle D; Buehler A; Doehner H; Rosenquist R; Stilgenbauer S
Article: CANCER LETTERS. 2008;259(2):138-145
B cell lymphomas express CX₃CR1 a non-B cell lineage adhesion molecule
Andreasson U; Ek S; Merz H; Rosenquist R; Andersen N; Jerkeman M; Dictor M; Borrebaeck CAK
Article: LEUKEMIA. 2008;22(2):339-343
The BCL-2 promoter (-938C>A) polymorphism does not predict clinical outcome in chronic lymphocytic leukemia
Kaderi MA; Norberg M; Murray F; Merup M; Sundstrom C; Roos G; Aleskog A; Karlsson K; Axelsson T; Tobin G; Rosenquist R
Article: BLOOD. 2008;111(3):1524-1533
Stereotyped patterns of somatic hypermutation in subsets of patients with chronic lymphocytic leukemia: implications for the role of antigen selection in leukemogenesis
Murray F; Darzentas N; Hadzidimitriou A; Tobin G; Boudjogra M; Scielzo C; Laoutaris N; Karlsson K; Baran-Marzsak F; Tsaftaris A; Moreno C; Anagnostopoulos A; Caligaris-Cappio F; Vaur D; Ouzounis C; Belessi C; Ghia P; Davi F; Rosenquist R; Stamatopoulos K
Article: GENOME BIOLOGY. 2008;9(9):R136
Segmentation-based detection of allelic imbalance and loss-of-heterozygosity in cancer cells using whole genome SNP arrays
Staaf J; Lindgren D; Vallon-Christersson J; Isaksson A; Goransson H; Juliusson G; Rosenquist R; Hoglund M; Borg A; Ringner M
Article: HAEMATOLOGICA. 2007;92(11):1495-1504
Thioredoxin, produced by stromal cells retrieved from the lymph node microenvironment, rescues chronic lymphocytic leukemia cells from apoptosis in vitro
Backman E; Bergh A-C; Lagerdahl I; Rydberg B; Sundstrom C; Tobin G; Rosenquist R; Linderholm M; Rosen A
Article: BRITISH JOURNAL OF CANCER. 2007;97(6):769-777
Upregulation of bfl-1 is a potential mechanism of chemoresistance in B-cell chronic lymphocytic leukaemia
Olsson A; Norberg M; Okvist A; Derkow K; Choudhury A; Tobin G; Celsing F; Osterborg A; Rosenquist R; Jondal M; Osorio LM
Article: LEUKEMIA RESEARCH. 2007;31(9):1219-1230
Detailed assessment of copy number alterations revealing homozygous deletions in 1p and 13q in mantle cell lymphoma
Thelander EF; Ichimura K; Collins VP; Walsh SH; Barbany G; Hagberg A; Laurell A; Rosenquist R; Larsson C; Lagercrantz S
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2007;138(1):68-71
Mast cell infiltration is a favourable prognostic factor in diffuse large B-cell lymphoma
Hedstrom G; Berglund M; Molin D; Fischer M; Nilsson G; Thunberg U; Book M; Sundstrom C; Rosenquist R; Roos G; Erlanson M; Amini R-M; Enblad G
Article: CELL. 2007;129(5):879-890
Downregulation of death-associated protein kinase 1 (DAPK1) in chronic lymphocytic leukemia
Raval A; Tanner SM; Byrd JC; Angerman EB; Perko JD; Chen S-S; Hackanson B; Grever MR; Lucas DM; MatkoviC JJ; Lin TS; Kipps TJ; Murray F; Weisenburger D; Sanger W; Lynch J; Watson P; Jansen M; Yoshinaga Y; Rosenquist R; de Jong PJ; Coggill P; Beck S; Lynch H; de la Chapelle A; Plass C
Article: BLOOD. 2007;109(7):2989-2998
Comprehensive characterization of IGHV3-21-expressing B-cell chronic lymphocytic leukemia: an Italian multicenter study
Bomben R; Dal Bo M; Capello D; Benedetti D; Marconi D; Zucchetto A; Forconi F; Maffei R; Ghia EM; Laurenti L; Bulian P; Del Principe MI; Palermo G; Thorselius M; Degan M; Campanini R; Guarini A; Del Poeta G; Rosenquist R; Efremov DG; Marasca R; Foa R; Gaidano G; Gattei V
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2007;78(4):283-289
Telomere length and correlation with histopathogenesis in B-cell leukemias/lymphomas
Walsh SH; Grabowski P; Berglund M; Thunberg U; Thorselius M; Tobin G; Aleskog A; Karlsson K; Sundstrom C; Laurell A; Enblad G; Rosenquist R; Roos G
Article: HEREDITARY CANCER IN CLINICAL PRACTICE. 2007;5(1):17-24
A hypothesis-generating search for new genetic breast cancer syndromes -: a national study in 803 Swedish families
von Wachenfeldt A; Lindblom A; Gronberg H; Einbeigi Z; Rosenquist R; Gardman C; Iselius L
Article: MODERN PATHOLOGY. 2007;20(1):63-75
Genomic imbalances during transformation from follicular lymphoma to diffuse large B-cell lymphoma
Berglund M; Enblad G; Thunberg U; Amini R-M; Sundstrom C; Roos G; Erlanson M; Rosenquist R; Larsson C; Lagercrantz S
Article: ARTHRITIS & RHEUMATOLOGY. 2006;54(12):3774-3781
Characteristics of diffuse large B cell lymphomas in rheumatoid arthritis
Baecklund E; Backlin C; Iliadou A; Granath F; Ekbom A; Amini R-M; Feltelius N; Enblad G; Sundstrom C; Klareskog L; Askling J; Rosenquist R
Article: BLOOD. 2006;107(7):2889-2894
Strikingly homologous immunoglobulin gene rearrangements and poor outcome inV_H3-21-using chronic lymphocytic leukemia patients independent of geographic origin and mutational status
Thorsélius M; Kröber A; Murray F; Thunberg U; Tobin G; Bühler A; Kienle D; Albesiano E; Maffei R; Dao-Ung LP; Wiley J; Vilpo J; Laurell A; Merup M; Roos G; Karlsson K; Chiorazzi N; Marasca R; Döhner H; Stilgenbauer S; Rosenquist R
Article: ARTHRITIS & RHEUMATOLOGY. 2006;54(3):692-701
Association of chronic inflammation, not its treatment, with increased lymphoma risk in rheumatoid arthritis
Baecklund E; Iliadou A; Askling J; Ekborn A; Backlin C; Granath F; Catrina AT; Rosenquist R; Feltelius N; Sundström C; Klareskog L
Article: LEUKEMIA. 2006;20(1):77-81
The G(-248)A polymorphism in the promoter region of the Bax gene does not correlate with prognostic markers or overall survival in chronic lymphocytic leukemia
Skogsberg Å; Tobin G; Kröber A; Kienle D; Thunberg U; Åleskog A; Karlsson K; Laurell A; Merup M; Vilpo J; Sundström C; Roos G; Jernerg-Wiklund H; Döhner H; Nilsson K; Stilgenbauer S; Rosenquist R
Article: LEUKEMIA. 2005;19(8):1452-1458
Insights into the multistep transformation process of lymphomas:: IgH-associated translocations and tumor suppressor gene mutations in clonally related composite Hodgkin's and non-Hodgkin's lymphomas
Schmitz R; Renné C; Rosenquist R; Tinguely M; Distler V; Menestrina F; Lestani M; Stankovic T; Austen B; Bräuninger A; Hansmann ML; Küppers R
Article: MODERN PATHOLOGY. 2005;18(8):1113-1120
Evaluation of immunophenotype in diffuse large B-cell lymphoma and its impact on prognosis
Berglund M; Thunberg U; Amini RM; Book M; Roos G; Erlanson M; Linderoth J; Dictor M; Jerkeman M; Cavallin-Ståhl E; Sundström C; Rehn-Eriksson S; Backlin C; Hagberg H; Rosenquist R; Enblad G
Article: BLOOD. 2005;106(2):681-689
Distinctive gene expression pattern in V_H3-21 utilizing B-cell chronic lymphocytic leukemia
Fält S; Merup M; Tobin G; Thunberg U; Gahrton G; Rosenquist R; Wennborg A
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2005;75(1):34-40
Mitogen induced activation, proliferation and surface antigen expression patterns in unmutated and hypermutated chronic lymphocytic leukemia cells
Vilpo J; Tobin G; Hulkkonen J; Hurme M; Thunberg U; Sundström C; Vilpo L; Rosenquist R
Article: LEUKEMIA RESEARCH. 2005;29(7):729-734
Lymphoplasmacytic lymphoma/Waldenstrom's macroglobulinemia derives from an extensively hypermutated B cell that lacks ongoing somatic hypermutation
Walsh SH; Laurell A; Sundström G; Roos L; Sundström C; Rosenquist R
Article: BLOOD. 2005;105(12):4807-4812
Telomere length as a prognostic parameter in chronic lymphocytic leukemia with special reference to V_H gene mutation status
Grabowski P; Hultdin M; Karlsson K; Tobin G; Åleskog A; Thunberg U; Laurell A; Sundström C; Rosenquist R; Roos G
Article: HAEMATOLOGICA. 2005;90(4):465-469
Patients with chronic lymphocytic leukemia with mutated V_H genes presenting with Binet stage B or C form a subgroup with a poor outcome
Tobin G; Thunberg U; Laurell A; Karlsson K; Aleskog A; Willander K; Soderberg O; Merup M; Vilpo J; Hultdin M; Sundstrom C; Roos G; Rosenquist R
Article: MODERN PATHOLOGY. 2005;18(3):331-339
Mantle cell lymphomas with clonal immunoglobulin V_H3-21 gene rearrangements exhibit fewer genomic imbalances than mantle cell lymphomas utilizing other immunoglobulin V_H genes
Thelander EF; Walsh SH; Thorsélius M; Laurell A; Landgren O; Larsson C; Rosenquist R; Lagercrantz S
Article: LEUKEMIA RESEARCH. 2005;29(2):153-158
Heterogeneous somatic hypermutation status confounds the cell of origin in hairy cell leukemia
Thorsélius M; Walsh SH; Thunberg U; Hagberg H; Sundström C; Rosenquist R
Article: LEUKEMIA & LYMPHOMA. 2004;45(12):2451-2454
Similar humoral immunity parameters in chronic lymphocytic leukemia patients independent of V_H gene mutation status
Sinisalo M; Aittoniemi J; Koski T; Tobin G; Thunberg U; Sundström C; Rosenquist R; Käyhty H; Vilpo J
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2004;73(6):407-411
V_H gene mutation status and cellular drug resistance in chronic lymphocytic leukaemia
Åleskog A; Tobin G; Laurell A; Thunberg U; Lindhagen E; Roos G; Nilsson K; Nygren P; Sundström C; Höglund M; Larsson R; Rosenquist R
Article: BLOOD. 2004;104(9):2879-2885
Subsets with restricted immunoglobulin gene rearrangement features indicate a role for antigen selection in the development of chronic lymphocytic leukemia
Tobin G; Thunberg U; Karlsson K; Murray F; Laurell A; Willander K; Enblad G; Merup M; Vilpo J; Juliusson G; Sundström C; Söderberg O; Roos G; Rosenquist R
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2004;73(3):210-214
Clonally related splenic marginal zone lymphoma and Hodgkin lymphoma with unmutated V gene rearrangements and a 15-yr time gap between diagnoses
Rosenquist R; Roos G; Erlanson M; Küppers R; Bräuninger A; Hansmann ML
Article: CANCER GENETICS. 2004;153(1):69-72
Different gene expression in immunoglobulin-mutated and immunoglobulin-unmutated forms of chronic lymphocytic leukemia
Ferrer A; Ollila J; Tobin G; Nagy B; Thunberg U; Aalto Y; Vihinen M; Vilpo J; Rosenquist R; Knuutila S
Article: LEUKEMIA & LYMPHOMA. 2004;45(2):221-228
V_H3-21 gene usage in chronic lymphocytic leukemia -: Characterization of a new subgroup with distinct molecular features and poor survival
Tobin G; Söderberg O; Thunberg U; Rosenquist R
Article: AMERICAN JOURNAL OF SURGICAL PATHOLOGY. 2003;27(11):1483-1488
Analysis of a clonally related mantle cell and Hodgkin lymphoma indicates Epstein-Barr virus infection of a Hodgkin/Reed-Sternberg cell precursor in a germinal center
Tinguely M; Rosenquist R; Sundström C; Amini RM; Küppers R; Hansmann ML; Bräuninger A
Article: GENES CHROMOSOMES & CANCER. 2003;37(4):417-420
More extensive genetic alterations in unmutated than in hypermutated cases of chronic lymphocytic leukemia
Karhu R; Tobin G; Thunberg U; Vilpo L; Sundström C; Knuutila S; Rosenquist R; Vilpo J
Article: BLOOD. 2003;101(12):4952-4957
Chronic lymphocytic leukemias utilizing the V_H3-21 gene display highly restricted V_λ2-14 gene use and homologous CDR3s:: implicating recognition of a common antigen epitope
Tobin G; Thunberg U; Johnson A; Eriksson I; Söderberg O; Karlsson K; Merup M; Juliusson G; Vilpo J; Enblad G; Sundström C; Roos G; Rosenquist R
Article: BLOOD. 2003;101(10):4047-4054
Mutated V_H genes and preferential V_H3-21 use define new subsets of mantle cell lymphoma
Walsh SH; Thorsélius M; Johnson A; Söderberg O; Jerkernan M; Björck E; Eriksson I; Thunberg U; Landgren O; Ehinger M; Löfvenberg E; Wallman K; Enblad G; Sander B; Porwit-MacDonald A; Dictor M; Olofsson T; Sundström C; Roos G; Rosenquist R
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2003;121(4):566-577
Cytogenetic abnormalities in childhood acute myeloid leukaemia:: a Nordic series comprising all children enrolled in the NOPHO-93-AML trial between 1993 and 2001
Forestier E; Heim S; Blennow E; Borgström G; Holmgren G; Heinonen K; Johannsson J; Kerndrup G; Andersen MK; Lundin C; Nordgren A; Rosenquist R; Swolin B; Johansson B
Article: LEUKEMIA RESEARCH. 2003;27(4):337-341
Ex vivo drug and irradiation sensitivities in hypermutated and unmutated forms of chronic lymphocytic leukemia cells
Kivekäs I; Tobin G; Thunberg U; Vilpo L; Sundström C; Rosenquist R; Vilpo J
Article: BRITISH JOURNAL OF CANCER. 2003;88(4):593-598
Association between telomere length and V_H gene mutation status in chronic lymphocytic leukaemia:: clinical and biological implications
Hultdin M; Rosenquist R; Thunberg U; Tobin G; Norrback KF; Johnson A; Sundström C; Roos G
Article: ACTA ONCOLOGICA. 2003;42(7):726-734
Genetic counselling for cancer and risk perception
Lidén A; Berglund G; Hansson MG; Rosenquist R; Sjödén PO; Nordin K
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2003;70(1):53-59
Surface antigen expression and correlation with variable heavy-chain gene mutation status in chronic lymphocytic leukemia
Vilpo J; Tobin G; Hulkkonen J; Hurme M; Thunberg U; Sundström C; Vilpo L; Rosenquist R
Article: LANCET. 2002;360(9349):1935-1939
Polymorphism in the P2X7 receptor gene and survival in chronic lymphocytic leukaemia
Thunberg U; Tobin G; Johnson A; Söderberg O; Padyukov L; Hultdin M; Klareskog L; Enblad G; Sundström C; Roos G; Rosenquist R
Article: CANCER GENETICS. 2002;139(1):38-43
Clonal development of a blastoid mantle cell lymphoma studied with comparative genomic hybridization
Flordal E; Berglund M; Rosenquist R; Erlanson M; Enblad G; Roos G; Larsson C; Lagercrantz S
Article: LEUKEMIA & LYMPHOMA. 2002;43(11):2179-2189
A novel B-cell line (U-2932) established from a patient with diffuse large B-cell lymphoma following Hodgkin lymphoma
Amini RM; Berglund M; Rosenquist R; Von Heideman A; Lagercrantz S; Thunberg U; Bergh J; Sundström C; Glimelius B; Enblad G
Article: EXPERIMENTAL HEMATOLOGY. 2002;30(10):1170-1177
Minimal residual disease quantification in childhood acute lymphoblastic leukemia by real-time polymerase chain reaction using the SYBR green dye
Li AH; Forestier E; Rosenquist R; Roos G
Article: JOURNAL OF MEDICAL GENETICS. 2002;39(9):689-694
Coping style, psychological distress, risk perception, and satisfaction in subjects attending genetic counselling for hereditary cancer
Nordin K; Lidén A; Hansson M; Rosenquist R; Berglund G
Article: MODERN PATHOLOGY. 2002;15(8):807-816
Chromosomal imbalances in diffuse large B-cell lymphoma detected by comparative genomic hybridization
Berglund M; Enblad G; Flordal E; Lui WO; Backlin C; Thunberg U; Sundström C; Roos G; Allander SV; Erlanson M; Rosenquist R; Larsson C; Lagercrantz S
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2002;68(4):217-224
Somatic hypermutation and V_H gene usage in mantle cell lymphoma
Thorsélius M; Walsh S; Eriksson I; Thunberg U; Johnson A; Backlin C; Enblad G; Sundström C; Roos G; Rosenquist R
Article: BLOOD. 2002;99(6):2262-2264
Somatically mutated Ig V_H3-21 genes characterize a new subset of chronic lymphocytic leukemia
Tobin G; Thunberg U; Johnson A; Thörn I; Söderberg O; Hultdin M; Botling J; Enblad G; Sällström J; Sundström C; Roos G; Rosenquist R
Article: LEUKEMIA RESEARCH. 2001;25(12):1033-1045
Detailed clonality analysis of relapsing precursor B acute lymphoblastic leukemia: implications for minimal residual disease detection
Li AH; Rosenquist R; Forestier E; Lindh J; Roos G
Article: BRITISH JOURNAL OF CANCER. 2000;82(3):601-607
Telomere length and telomerase activity in malignant lymphomas at diagnosis and relapse
Remes K; Norrback KF; Rosenquist R; Mehle C; Lindh J; Roos G
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 1999;63(4):211-218
Clonal rearrangements in childhood and adult precursor B acute lymphoblastic leukemia:: a comparative polymerase chain reaction study using multiple sets of primers
Li AH; Rosenquist R; Forestier E; Holmberg D; Lindh J; Löfvenberg E; Roos G
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 1999;63(3):171-179
Clonal evolution as judged by immunoglobulin heavy chain gene rearrangements in relapsing precursor-B acute lymphoblastic leukemia
Rosenquist R; Thunberg U; Li AH; Forestier E; Lönnerholm G; Lindh J; Sundström C; Sällstrom J; Holmberg D; Roos G
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 1999;62(2):123-128
V_H gene family utilization in different B-cell lymphoma subgroups
Rosenquist R; Lindström A; Holmberg D; Lindh J; Roos G
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 1998;61(3):164-172
Low rate of somatic hypermutations characterize progressive B-cell lymphomas
Rosenquist R; Lindström A; Li AH; Roos G; Lindh J; Holmberg D
Article: ACTA ONCOLOGICA. 1998;37(2):193-200
Alterations of the immunoglobulin heavy chain locus in progressive B-cell lymphomas
Rosenquist R; Linderholm B; Lindström A; Hagberg H; Sundström C; Roos G; Holmberg D; Lindh J
Article: DIAGNOSTIC MOLECULAR PATHOLOGY. 1997;6(3):140-146
Comparative analysis of detection systems for evaluation of PCR amplified immunoglobulin heavy-chain gene rearrangements
Thunberg U; Rosenquist R; Lindstrom A; Lindh J; Sundstrom C; Roos G; Sallstrom J
Article: MOLECULAR IMMUNOLOGY. 1997;34(4):305-313
Immunoglobulin V-H gene replacements in a T-cell lymphoblastic lymphoma
Rosenquist R; Lindh J; Roos G; Holmberg D
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Review: LEUKEMIA. 2025;:1-12
Resistance to targeted therapies in chronic lymphocytic leukemia: Current status and perspectives for clinical and diagnostic practice
Blombery P; Chatzikonstantinou T; Gerousi M; Rosenquist R; Gaidano G; Pospisilova S; Roberts AW; Birkinshaw RW; Rossi D; Scarfo L; Seymour JF; Stilgenbauer S; Wiestner A; Woyach JA; Brown JR; Ghia P; Stamatopoulos K
Letter: NATURE MEDICINE. 2025;31(6):1730-1732
Precision Omics Initiative Sweden (PROMISE) will integrate research with healthcare
Kampe A; Gudmundsson S; Walsh CP; Lindblad-Toh K; Johansson A; Clareborn A; Ameur A; Edsjo A; Fioretos T; Ehrencrona H; Eriksson D; Fall T; Franks PW; Gyllensten U; Haag M; Hagwall A; Johansson Soller M; Lehtio J; Lu Y; Magnusson PKE; Melen E; Melin B; Michaelsson K; Nordgren A; Nordlund J; Saal LH; Schwenk JM; Sikora P; Sundstrom J; Taylan F; Van Guelpen B; Wadelius M; Wedell A; Wirta V; Ostling P; Jacobsson B; Sjoblom T; Persson B; Rosenquist R; Lindstrand A; Lappalainen T
Editorial comment: BLOOD. 2025;145(21):2403-2405
Chromatin dynamics in CLL: a matter of balance.
Rosenquist R
Editorial comment: NATURE GENETICS. 2024;56(11):2287-2294
Pushing the boundaries of rare disease diagnostics with the help of the first Undiagnosed Hackathon
Delgado-Vega AM; Cederroth H; Taylan F; Ekholm K; Ek M; Thonberg H; Jemt A; Nilsson D; Eisfeldt J; Saether KB; Hoijer I; Akgun-Dogan O; Asano Y; Barakat TS; Batkovskyte D; Baynam G; Bodamer O; Chetruengchai W; Corcoran P; Couse M; Danis D; Demidov G; Dohi E; Erhardsson M; Fernandez-Luna L; Fujiwara T; Garg N; Giugliani R; Gonzaga-Jauregui C; Grigelioniene G; Groza T; Gunnarsson C; Hammarsjo A; Hammond CK; Ng OH; Hesketh S; Hettiarachchi D; Soller MJ; Kirmani UA; Kjellberg M; Kvarnung M; Kvlividze O; Lagerstedt-Robinson K; Lasko P; Lassmann T; Lau LYS; Laurie S; Lim WK; Liu Z; Wiklander ML; Makay P; Maiga AB; Maya-Gonzalez C; Meyn MS; Neethiraj R; Nigro V; Nordgren F; Nordlund J; Orrsjo S; Ottosson J; Ozbek U; Ozdemir O; Partin C; Pearce DA; Peck R; Pedersen A; Pettersson M; Pongpanich M; de la Paz MP; Ramani A; Romero JA; Romero VI; Rosenquist R; Saw AM; Spencer M; Stattin E-L; Srichomthong C; Tapia-Paez I; Taruscio D; Taylor JP; Tkemaladze T; Tully I; Tumer Z; van Zelst-Stams WAG; Verloes A; Vasterviga E; Wang S; Yang R; Yamamoto S; Yepez VA; Zhang Q; Shotelersuk V; Wiafe SA; Alanay Y; Botto LD; Kirmani S; Lumaka A; Palmer EE; Puri RD; Wirta V; Lindstrand A; Buske OJ; Cederroth M; Nordgren A
Review: HEMASPHERE. 2024;8(7):e113
Realizing precision medicine in chronic lymphocytic leukemia: Remaining challenges and potential opportunities
Stamatopoulos K; Pavlova S; Al-Sawaf O; Chatzikonstantinou T; Karamanidou C; Gaidano G; Cymbalista F; Kater AP; Rawstron A; Scarfo L; Ghia P; Rosenquist R
Review: LEUKEMIA. 2024;38(7):1455-1468
ERIC recommendations for TP53 mutation analysis in chronic lymphocytic leukemia-2024 update
Malcikova J; Pavlova S; Baliakas P; Chatzikonstantinou T; Tausch E; Catherwood M; Rossi D; Soussi T; Tichy B; Kater AP; Niemann CU; Davi F; Gaidano G; Stilgenbauer S; Rosenquist R; Stamatopoulos K; Ghia P; Pospisilova S
Editorial comment: NATURE GENETICS. 2024;56(5):733-736
The 1+Million Genomes Minimal Dataset for Cancer
Riba M; Sala C; Culhane AC; Flobak A; Patocs A; Boye K; Plevova K; Pospisilova S; Gandolfi G; Morelli MJ; Bucci G; Edsjo A; Lassen U; Al-Shahrour F; Lopez-Bigas N; Hovland R; Cuppen E; Valencia A; Poirel HA; Rosenquist R; Scollen S; Marquez JA; Belien J; De Nicolo A; De Maria R; Torrents D; Tonon G
Editorial comment: BLOOD. 2024;143(17):1682-1684
New signature predicts MBL-to-CLL progression.
Rosenquist R
Review: MOLECULAR ASPECTS OF MEDICINE. 2024;96:101250
Current and emerging sequencing-based tools for precision cancer medicine.
Edsjö A; Gisselsson D; Staaf J; Holmquist L; Fioretos T; Cavelier L; Rosenquist R
Letter: LEUKEMIA. 2024;38(3):679-680
Updates of the ERIC recommendations on how to report the results from immunoglobulin heavy variable gene analysis in chronic lymphocytic leukemia
Chatzikonstantinou T; Agathangelidis A; Chatzidimitriou A; Tresoldi C; Davis Z; Giudicelli V; Kossida S; Belessi C; Rosenquist R; Ghia P; Langerak AW; Davi F; Stamatopoulos K
Review: BLOOD ADVANCES. 2023;7(23):7382-7383
Time to include IGLV3-21R110 status in CLL prognostication?
Rosenquist R
Review: JOURNAL OF INTERNAL MEDICINE. 2023;294(4):437-454
Implementation of precision medicine in healthcare-A European perspective
Stenzinger A; Moltzen EK; Winkler E; Molnar-Gabor F; Malek N; Costescu A; Jensen BN; Nowak F; Pinto C; Ottersen OP; Schirmacher P; Nordborg J; Seufferlein T; Froehling S; Edsjoe A; Garcia-Foncillas J; Normanno N; Lundgren B; Friedman M; Bolanos N; Tatton-Brown K; Hill S; Rosenquist R
Review: JOURNAL OF INTERNAL MEDICINE. 2023;294(4):413-436
Novel precision medicine approaches and treatment strategies in hematological malignancies
Rosenquist R; Bernard E; Erkers T; Scott DW; Itzykson R; Rousselot P; Soulier J; Hutchings M; Ostling P; Cavelier L; Fioretos T; Smedby KE
Corrigendum: LEUKEMIA. 2023;37(9):1944-1951
The 5th edition of The World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms (vol 36, pg 1720, 2022)
Alaggio R; Amador C; Anagnostopoulos I; Attygalle AD; de Oliveira Araujo IB; Berti E; Bhagat G; Borges AM; Boyer D; Calaminici M; Chadburn A; Chan JKC; Cheuk W; Chng W-J; Choi JK; Chuang S-S; Coupland SE; Czader M; Dave SS; de Jong D; Di Napoli A; Du M-Q; Elenitoba-Johnson KS; Ferry J; Geyer J; Gratzinger D; Guitart J; Gujral S; Harris M; Harrison CJ; Hartmann S; Hochhaus A; Jansen PM; Karube K; Kempf W; Khoury J; Kimura H; Klapper W; Kovach AE; Kumar S; Lazar AJ; Lazzi S; Leoncini L; Leung N; Leventaki V; Li X-Q; Lim MS; Liu W-P; Louissaint AJ; Marcogliese A; Medeiros LJ; Michal M; Miranda RN; Mitteldorf C; Montes-Moreno S; Morice W; Nardi V; Naresh KN; Natkunam Y; Ng S-B; Oschlies I; Ott G; Parrens M; Pulitzer M; Rajkumar SV; Rawstron AC; Rech K; Rosenwald A; Said J; Sarkozy C; Sayed S; Saygin C; Schuh A; Sewell W; Siebert R; Sohani AR; Suzuki R; Tooze R; Traverse-Glehen A; Vega F; Vergier B; Wechalekar AD; Wood B; Xerri L; Xiao W; Akinola NO; Akkari Y; Allende LM; Aozasa K; Araujo I; Arcaini L; Ardeshna KM; Asano N; Attarbaschi A; Bacon CM; Barrans SL; Batchelor T; Battistella M; Baughn LB; Behdad A; Berentsen S; Bianchi G; Bledsoe J; Borchmann P; Bower M; Buldini B; Burger JA; Burkhardt B; Cassaday RD; Cazzaniga G; Cerf-Bensussan N; Cesarman E; Chandy M; Chapman JR; Chapuy B; Chen X; Cheng CL; Chiattone C; Chiorazzi N; Cook LB; Cooper WA; Corboy GP; Cowan AJ; Cozzolino I; Cree IA; d'Amore ESG; Davies AJ; Deckert M; Delabie J; Demicco EG; Deshpande V; Diepstra A; Dierickx D; Dunleavy K; Eichhorst B; Ennishi D; Fajgenbaum DC; Farinha P; Fernandez de Larrea C; Fisher KE; Fitzgibbon J; Flanagan M; Fromm J; Garcia JF; Geddie WR; Gertz M; Gopal A; Gopal S; Greipp PT; Gru A; Gupta R; Hansmann M-L; Hebeda KM; Herfarth K; Herling M; Hermine O; Khe H-X; Hodge J; Hu S; Huang Y; Hung YP; Hunger S; Inaba H; Inagaki H; Iqbal J; Ishitsuka K; Iwaki N; Iwatsuki K; Jain N; Jeon YK; Kadin M; Kaji S; Kakkar A; Karadimitris A; Kataoka K; Kato S; Kersten MJ; Ketterling RP; Kim JE; Kratz CP; Kridel R; Kristinsson S; Kuppers R; Kuzu I; Yok-Lam; Lacasce A; Lamant-Rochaix L; Lamy T; Landgren O; Laskar S; Laskin WB; Lenz G; Li S; Di Li G; Lin P; Locatelli F; Lorsbach RB; Lossos I; Loughran TPJ; Macon WR; Maleszewski JJ; Malhotra P; Marafioti T; Maruyama D; Marx A; Mbulaiteye SM; Meignin V; Mejstrikova E; Michelow P; Miettinen M; Miles RR; Miyoshi H; Molina TJ; Mollejo M; Momose S; Mori T; Morice WG; Nadel B; Nagai H; Nagane M; Nair R; Nakamura N; Nakazawa A; Nasr S; Nicholson AG; Nicolae A; Ohgami RS; Oishi N; Olson TS; Ortonne N; Paiva B; Pan-Hammarstrom Q; Parihar M; Paulli M; Petersen A; Picarsic J; Pileri A; Pimpinelli N; Plaza JA; Rabin KR; Raderer M; Rai K; Randen U; Rao H; Robson A; Rochford R; Rosenquist R; Rossi D; Rossi ED; Rule S; Rymkiewicz G; Sabattini E; Saha V; Sakata-Yanagimoto M; Sander CA; Sangueza JM; Sangueza OP; Santucci M; Sato Y; Satou A; Schafernak KT; Schmitt F; Semenzato G; Sengar M; Shanafelt T; Shimada K; Slack GW; Slager S; Soffietti R; Solomon DA; Stamatopoulos K; Steidl C; Stilgenbauer S; Sukswai N; Takeuchi K; Tallini G; Tamaru J; Tan S-Y; Tembhare P; Tiacci E; Tokura Y; Tournilhac O; Treon S; Truemper L; Tsukasaki K; van Rhee F; Varghese A; Vermeer MH; Vielh P; Walker B; Wang M; Wang H-Y; Wang Z; Watanabe T; Weigert O; Wein-Stock D; Whittaker SJ; Willemze R; Woessmann W; Wu CJ; Yamaguchi M; Yamamoto H; Yamashita D; Yang S; Yang DT; Yasuda T; Yin W-H; Zen Y; Zhao S; Zhao W-L
Letter: ACTA ONCOLOGICA. 2023;62(6):560-564
The BioLymph study - implementing precision medicine approaches in lymphoma diagnostics, treatment and follow-up: feasibility and first results
Smedby KE; Waesterlid T; Tham E; Haider Z; Joelsson J; Thorvaldsdottir B; Krstic A; Wahlin BE; Foroughi-Asl H; Karlsson C; Eloranta S; Saft L; Palma M; Kwiecinska A; Hansson L; Osterborg A; Wirta V; Rassidakis G; Sander B; Sonnevi K; Rosenquist R
Corrigendum: LEUKEMIA. 2023;37(2):504
Different prognostic impact of recurrent gene mutations in chronic lymphocytic leukemia depending on IGHV gene somatic hypermutation status: a study by ERIC in HARMONY (Dec, 10.1038/s41375-022-01802-y, 2022)
Mansouri L; Thorvaldsdottir B; Sutton L-A; Karakatsoulis G; Meggendorfer M; Parker H; Nadeu F; Brieghel C; Laidou S; Moia R; Rossi D; Catherwood M; Kotaskova J; Delgado J; Rodriguez-Vicente AE; Benito R; Rigolin GM; Bonfiglio S; Scarfo L; Mattsson M; Davis Z; Gogia A; Rani L; Baliakas P; Foroughi-Asl H; Jylha C; Skaftason A; Rapado I; Miras F; Martinez-Lopez J; de la Serna J; Rivas JMH; Thornton P; Larrayoz MJ; Calasanz MJ; Fesus V; Matrai Z; Bodor C; Smedby KE; Espinet B; Puiggros A; Gupta R; Bullinger L; Bosch F; Tazon-Vega B; Baran-Marszak F; Oscier D; Nguyen-Khac F; Zenz T; Terol MJ; Cuneo A; Hernandez-Sanchez M; Pospisilova S; Mills K; Gaidano G; Niemann CU; Campo E; Strefford JC; Ghia P; Stamatopoulos K; Rosenquist R
Editorial comment: FRONTIERS IN ONCOLOGY. 2023;13:1252189
Editorial: The promise of immunogenetics for precision oncology
Vlachonikola E; Langerak AW; Rosenquist R; Chatzidimitriou A
Review: FRONTIERS IN ONCOLOGY. 2023;13:1143811
Recent revelations and future directions using single-cell technologies in chronic lymphocytic leukemia
Oder B; Chatzidimitriou A; Langerak AW; Rosenquist R; Osterholm C
Review: FRONTIERS IN ONCOLOGY. 2023;13:1146486
Precision diagnostics in chronic lymphocytic leukemia: Past, present and future
Mollstedt J; Mansouri L; Rosenquist R
Review: CAMBRIDGE PRISMS: PRECISION MEDICINE. 2023;1:e15
Building a precision medicine infrastructure at a national level: The Swedish experience.
Edsjö A; Lindstrand A; Gisselsson D; Mölling P; Friedman M; Cavelier L; Johansson M; Ehrencrona H; Fagerqvist T; Strid T; Lovmar L; Jacobsson B; Johansson Å; Engstrand L; Wheelock CE; Sikora P; Wirta V; Fioretos T; Rosenquist R; Genomic Medicine Sweden (GMS)
Letter: NATURE MEDICINE. 2022;28(10):1980-1982
Implementing precision medicine in a regionally organized healthcare system in Sweden
Fioretos T; Wirta V; Cavelier L; Berglund E; Friedman M; Akhras M; Botling J; Ehrencrona H; Engstrand L; Helenius G; Fagerqvist T; Gisselsson D; Gruvberger-Saal S; Gyllensten U; Heidenblad M; Hoglund K; Jacobsson B; Johansson M; Johansson A; Soller MJ; Landstrom M; Larsson P; Levin L-A; Lindstrand A; Lovmar L; Lyander A; Melin M; Nordgren A; Nordmark G; Molling P; Palmqvist L; Palmqvist R; Repsilber D; Sikora P; Stenmark B; Soderkvist P; Stranneheim H; Strid T; Wheelock CE; Wadelius M; Wedell A; Edsjo A; Rosenquist R
Editorial comment: SEMINARS IN CANCER BIOLOGY. 2022;84:1-2
Precision medicine in cancer: A paradigm shift
Rosenquist R; Frohling S; Stamatopoulos K
Review: SEMINARS IN CANCER BIOLOGY. 2022;84:16-22
Analytical demands to use whole-genome sequencing in precision oncology
Meggendorfer M; Jobanputra V; Wrzeszczynski KO; Roepman P; de Bruijn E; Cuppen E; Buttner R; Caldas C; Grimmond S; Mullighan CG; Elemento O; Rosenquist R; Schuh A; Haferlach T
Review: SEMINARS IN CANCER BIOLOGY. 2022;84:32-39
Clinical utility of whole-genome sequencing in precision oncology
Rosenquist R; Cuppen E; Buettner R; Caldas C; Dreau H; Elemento O; Frederix G; Grimmond S; Haferlach T; Jobanputra V; Meggendorfer M; Mullighan CG; Wordsworth S; Schuh A
Review: JOURNAL OF INTERNAL MEDICINE. 2022;292(2):221-242
Towards precision medicine in lymphoid malignancies
Buhler MM; Martin-Subero JI; Pan-Hammarstrom Q; Campo E; Rosenquist R
Review: LEUKEMIA. 2022;36(8):1961-1968
Immunoglobulin gene sequence analysis in chronic lymphocytic leukemia: the 2022 update of the recommendations by ERIC, the European Research Initiative on CLL
Agathangelidis A; Chatzidimitriou A; Chatzikonstantinou T; Tresoldi C; Davis Z; Giudicelli V; Kossida S; Belessi C; Rosenquist R; Ghia P; Langerak AW; Davi F; Stamatopoulos K
Editorial comment: BLOOD. 2021;138(23):2305-2307
The more complex, the worse outcome in CLL
Rosenquist R
Meeting abstract: BLOOD. 2021;138:3515
Mutations of the Novel Tumor Suppressor Gene SAMHD1 Are Frequent and Correlate with Decreased Protein Expression in Peripheral T-Cell Lymphomas (PTCL)
Kokaraki G; Xagoraris I; Da Silva PFN; Sutton LA; Falcao RM; de Souza JES; Osterborg A; Wirta V; Brandell RR; Rassidakis GZ
Editorial comment: JCO PRECISION ONCOLOGY. 2021;5:974-980
Discordant Reporting of a Previously CD Undescribed Pathogenic Germline BRCA2 Variant in Blood and Tumor Tissue in a Patient With Pancreatic Adenocarcinoma
Kordes M; Tamborero D; Lagerstedt-Robinson K; Yachnin J; Rosenquist R; Lohr J-M; Liljefors MG
Letter: LEUKEMIA & LYMPHOMA. 2021;62(11):2808-2811
Mutations known from B-cell lymphoid malignancies are not found in CD34⁺ stem cells from patients with lymphoma
Husby S; Favero F; Rodriguez-Gonzalez FG; Sutton LA; Haastrup EK; Orskov AD; Hansen JW; Arboe B; Aslan D; Clasen-Linde E; Rahbek Gjerdrum LM; Gorlev JS; Brown P; Fischer-Nielsen A; Rosenquist R; Weischenfeldt J; Gronbaek K
Review: JOURNAL OF INTERNAL MEDICINE. 2021;290(3):602-620
Technological readiness and implementation of genomic-driven precision medicine for complex diseases
Franks PW; Melen E; Friedman M; Sundstrom J; Kockum I; Klareskog L; Almqvist C; Bergen SE; Czene K; Hagg S; Hall P; Johnell K; Malarstig A; Catrina A; Hagstrom H; Benson M; Smith JG; Gomez MF; Orho-Melander M; Jacobsson B; Halfvarson J; Repsilber D; Oresic M; Jern C; Melin B; Ohlsson C; Fall T; Ronnblom L; Wadelius M; Nordmark G; Johansson A; Rosenquist R; Sullivan PF
Letter: HEMASPHERE. 2021;5(3):e546
Assessing Patients' Knowledge on Chronic Lymphocytic Leukemia: Validation of the ERIC CLL Knowledge Questionnaire in Greece
Karamanidou C; Xochelli A; Papaioannou M; Moysiadis T; Scarfo L; Mattsson M; Stavroyianni N; Rosenquist R; Ghia P; Stamatopoulos K
Published conference paper: BLOOD. 2021;137(2):216-231
Triggering interferon signaling in T cells with avadomide sensitizes CLL to anti-PD-L1 /PD-1 immunotherapy
Ioannou N; Hagner PR; Stokes M; Gandhi AK; Apollonio B; Fanous M; Papazoglou D; Sutton L-A; Rosenquist R; Amini R-M; Chiu H; Lopez-Girona A; Janardhanan P; Awan FT; Jones J; Kay NE; Shanafelt TD; Tallman MS; Stamatopoulos K; Patten PEM; Vardi A; Ramsay AG
Editorial comment: HAEMATOLOGICA. 2019;104(10):1914-1916
p66Shc deficiency sets the scene for clinically aggressive chronic lymphocytic leukemia
Rosenquist R
Review: JOURNAL OF INTERNAL MEDICINE. 2019;286(2):118-136
Cell-free tumour DNA testing for early detection of cancer - a potential future tool
Barbany G; Arthur C; Lieden A; Nordenskjold M; Rosenquist R; Tesi B; Wallander K; Tham E
Letter: LEUKEMIA. 2019;33(7):1801-1805
Different time-dependent changes of risk for evolution in chronic lymphocytic leukemia with mutated or unmutated antigen B cell receptors
Moysiadis T; Baliakas P; Rossi D; Catherwood M; Strefford JC; Delgado J; Anagnostopoulos A; Belessi C; Stavroyianni N; Pospisilova S; Oscier D; Gaidano G; Campo E; Rosenquist R; Ghia P; Stamatopoulos K
Letter: HAEMATOLOGICA. 2019;104(5):e208-e210
Long-term real-world results of ibrutinib therapy in patients with relapsed or refractory chronic lymphocytic leukemia: 30-month follow up of the Swedish compassionate use cohort
Winqvist M; Andersson P-O; Asklid A; Karlsson K; Karlsson C; Lauri B; Lundin J; Mattsson M; Norin S; Sandstedt A; Rosenquist R; Spath F; Hansson L; Osterborg A
Review: HAEMATOLOGICA. 2018;103(12):1956-1968
TP53 aberrations in chronic lymphocytic leukemia: an overview of the clinical implications of improved diagnostics
Campo E; Cymbalista F; Ghia P; Jaeger U; Pospisilova S; Rosenquist R; Schuh A; Stilgenbauer S
Editorial comment: BLOOD. 2018;132(22):2317-2319
Not so lost in translation: RPS15 mutations in CLL
Ljungstrom V; Rosenquist R
Editorial comment: SEMINARS IN CANCER BIOLOGY. 2018;51:iv-v
Introduction: Epigenetics in cancer
Rosenquist R; Esteller M; Plass C
Review: LEUKEMIA. 2018;32(5):1070-1080
ERIC recommendations for TP53 mutation analysis in chronic lymphocytic leukemia-update on methodological approaches and results interpretation
Malcikova J; Tausch E; Rossi D; Sutton LA; Soussi T; Zenz T; Kater AP; Niemann CU; Gonzalez D; Davi F; Gonzalez Diaz M; Moreno C; Gaidano G; Stamatopoulos K; Rosenquist R; Stilgenbauer S; Ghia P; Pospisilova S
Letter: HAEMATOLOGICA. 2018;103(4):e158-e161
No improvement in long-term survival over time for chronic lymphocytic leukemia patients in stereotyped subsets #1 and #2 treated with chemo(immuno)therapy
Baliakas P; Mattsson M; Hadzidimitriou A; Minga E; Agathangelidis A; Sutton L-A; Scarfo L; Davis Z; Yan X-J; Plevova K; Sandberg Y; Vojdeman FJ; Tzenou T; Chu CC; Veronese S; Mansouri L; Smedby KE; Giudicelli V; Nguyen-Khac F; Panagiotidis P; Juliusson G; Anagnostopoulos A; Lefranc M-P; Trentin L; Catherwood M; Montillo M; Niemann CU; Langerak AW; Pospisilova S; Stavroyianni N; Chiorazzi N; Oscier D; Jelinek DF; Shanafelt T; Darzentas N; Belessi C; Davi F; Ghia P; Rosenquist R; Stamatopoulos K
Editorial comment: JOURNAL OF INTERNAL MEDICINE. 2017;282(5):358-359
Introduction to the symposium 'Targeted therapy in B-cell malignancies'
Smedby KE; Rosenquist R
Published conference paper: JOURNAL OF INTERNAL MEDICINE. 2017;282(5):371-394
Genetic landscape and deregulated pathways in B-cell lymphoid malignancies
Rosenquist R; Bea S; Du M-Q; Nadel B; Pan-Hammarstrom Q
Editorial comment: LEUKEMIA. 2017;31(7):1477-1481
Immunoglobulin gene sequence analysis in chronic lymphocytic leukemia: updated ERIC recommendations
Rosenquist R; Ghia P; Hadzidimitriou A; Sutton L-A; Agathangelidis A; Baliakas P; Darzentas N; Giudicelli V; Lefranc M-P; Langerak AW; Belessi C; Davi F; Stamatopoulos K
Editorial comment: HAEMATOLOGICA. 2017;102(6):968-971
Immunoglobulin genes in chronic lymphocytic leukemia: key to understanding the disease and improving risk stratification
Sutton L-A; Hadzidimitriou A; Baliakas P; Agathangelidis A; Langerak AW; Stilgenbauer S; Pospisilova S; Davis Z; Forconi F; Davi F; Ghia P; Rosenquist R; Stamatopoulos K
Review: LEUKEMIA. 2017;31(2):282-291
Antigen receptor stereotypy in chronic lymphocytic leukemia
Stamatopoulos K; Agathangelidis A; Rosenquist R; Ghia P
Editorial comment: CANCER CELL. 2016;30(5):665-667
Unraveling the DNA Methylome in Mantle Cell Lymphoma: New Insights into the Cellular Origin
Mansouri L; Rosenquist R
Review: HAEMATOLOGICA. 2016;101(9):1002-1009
Clinical impact of recurrently mutated genes on lymphoma diagnostics: state-of-the-art and beyond
Rosenquist R; Rosenwald A; Du M-Q; Gaidano G; Groenen P; Wotherspoon A; Ghia P; Gaulard P; Campo E; Stamatopoulos K
Letter: HAEMATOLOGICA. 2016;101(9):e369-e373
ATM mutations in major stereotyped subsets of chronic lymphocytic leukemia: enrichment in subset #2 is associated with markedly short telomeres
Navrkalova V; Young E; Baliakas P; Radova L; Sutton L-A; Plevova K; Mansouri L; Ljungstrom V; Ntoufa S; Davis Z; Juliusson G; Smedby KE; Belessi C; Panagiotidis P; Touloumenidou T; Davi F; Langerak AW; Ghia P; Strefford JC; Oscier D; Mayer J; Stamatopoulos K; Pospisilova S; Rosenquist R; Trbusek M
Editorial comment: SEMINARS IN CANCER BIOLOGY. 2016;39:1-2
B-cell malignancies: All roads lead to NF-κB activation
Rosenquist R; Stamatopoulos K
Review: SEMINARS IN CANCER BIOLOGY. 2016;39:40-48
NF-κB activation in chronic lymphocytic leukemia: A point of convergence of external triggers and intrinsic lesions
Mansouri L; Papakonstantinou N; Ntoufa S; Stamatopoulos K; Rosenquist R
Letter: HAEMATOLOGICA. 2016;101(7):e299-e302
Additional trisomies amongst patients with chronic lymphocytic leukemia carrying trisomy 12: the accompanying chromosome makes a difference
Baliakas P; Puiggros A; Xochelli A; Sutton L-A; Nguyen-Khac F; Gardiner A; Plevova K; Minga E; Hadzidimitriou A; Walewska R; McCarthy H; Ortega M; Collado R; Gonzalez T; Granada I; Luno E; Kotaskova J; Moysiadis T; Davis Z; Stavroyianni N; Anagnostopoulos A; Strefford JC; Pospisilova S; Davi F; Athanasiadou A; Rosenquist R; Oscier D; Espinet B; Stamatopoulos K
Editorial comment: BLOOD. 2016;127(17):2052-2054
Not all subclones matter in CLL
Sutton L-A; Rosenquist R
Review: JOURNAL OF INTERNAL MEDICINE. 2016;279(4):347-357
Prognostic indices in chronic lymphocytic leukaemia: where do we stand how do we proceed?
Baliakas P; Mattsson M; Stamatopoulos K; Rosenquist R
Editorial comment: HAEMATOLOGICA. 2016;101(3):263-265
Innovation In the prognostication of chronic lymphocytic leukemia: how far beyond TP53 gene analysis can we go?
Pospisilova S; Sutton L-A; Malcikova J; Tausch E; Rossi D; Montserrat E; Moreno C; Stamatopoulos K; Gaidano G; Rosenquist R; Ghia P
Editorial comment: LEUKEMIA & LYMPHOMA. 2015;56(11):3008-3009
A new piece to the stereotypy "puzzle" in chronic lymphocytic leukemia
Rosenquist R
Review: SEMINARS IN CANCER BIOLOGY. 2015;34:22-35
The complex interplay between cell-intrinsic and cell-extrinsic factors driving the evolution of chronic lymphocytic leukemia
Sutton L-A; Rosenquist R
Letter: BLOOD. 2015;126(8):1043-1044
Prognostic relevance of MYD88 mutations in CLL: the jury is still out
Baliakas P; Hadzidimitriou A; Agathangelidis A; Rossi D; Sutton L-A; Kminkova J; Scarfo L; Pospisilova S; Gaidano G; Stamatopoulos K; Ghia P; Rosenquist R
Letter: LEUKEMIA. 2015;29(3):748-751
Common variation at 12q24.13 (OAS3) influences chronic lymphocytic leukemia risk
Sava GP; Speedy HE; Di Bernardo MC; Dyer MJS; Holroyd A; Sunter NJ; Marr H; Mansouri L; Deaglios S; Karabon L; Frydecka I; Jamroziak K; Woszczyk D; Juliusson G; Smedby KE; Jayne S; Majid A; Wang Y; Dearden C; Hall AG; Mainou-Fowler T; Jackson GH; Summerfield G; Harris RJ; Pettitt AR; Allsup DJ; Bailey JR; Pratt G; Pepper C; Fegan C; Rosenquist R; Catovsky D; Allan JM; Houlston RS
Review: EXPERT REVIEW OF HEMATOLOGY. 2015;8(1):71-78
Clonal evolution in chronic lymphocytic leukemia: impact of subclonality on disease progression
Sutton L-A; Rosenquist R
Review: HAEMATOLOGICA. 2015;100(1):7-16
Deciphering the molecular landscape in chronic lymphocytic leukemia: time frame of disease evolution
Sutton L-A; Rosenquist R
Review: CANCER RESEARCH. 2014;74(16):4211-4216
Immunogenetic Studies of Chronic Lymphocytic Leukemia: Revelations and Speculations about Ontogeny and Clinical Evolution
Vardi A; Agathangelidis A; Sutton L-A; Ghia P; Rosenquist R; Stamatopoulos K
Letter: BRITISH JOURNAL OF HAEMATOLOGY. 2014;166(4):621-625
The frequency of TP53 gene defects differs between chronic lymphocytic leukaemia subgroups harbouring distinct antigen receptors
Malcikova J; Stalika E; Davis Z; Plevova K; Trbusek M; Mansouri L; Scarfo L; Baliakas P; Gardiner A; Sutton L-A; Francova HS; Agathangelidis A; Anagnostopoulos A; Tracy I; Makris A; Smardova J; Ghia P; Belessi C; Gonzalez D; Rosenquist R; Oscier D; Pospisilova S; Stamatopoulos K
Letter: LEUKEMIA. 2014;28(3):710-713
On the way towards a 'CLL prognostic index': focus on TP53, BIRC3, SF3B1, NOTCH1 and MYD88 in a population-based cohort
Cortese D; Sutton L-A; Cahill N; Smedby KE; Geisler C; Gunnarsson R; Juliusson G; Mansouri L; Rosenquist R
Letter: LEUKEMIA. 2014;28(3):694-696
Feasibility of targeted next-generation sequencing of the TP53 and ATM genes in chronic lymphocytic leukemia
Mansouri L; Sutton L-A; Ljungstrom V; Sorqvist EF; Gunnarsson R; Smedby KE; Juliusson G; Stamatopoulos K; Nilsson M; Rosenquist R
Editorial comment: SEMINARS IN CANCER BIOLOGY. 2014;24:1-2
The microenvironment in lymphomas - Dissecting the complex crosstalk between tumor cells and 'by-stander' cells
Rosenquist R; Davi F; Ghia P
Review: SEMINARS IN CANCER BIOLOGY. 2014;24:61-70
Lymphoma development in patients with autoimmune and inflammatory disorders - What are the driving forces?
Baecklund E; Smedby KE; Sutton L-A; Askling J; Rosenquist R
Editorial comment: SEMINARS IN CANCER BIOLOGY. 2013;23(6):397-398
Antigens in lymphoma development-Current knowledge and future directions Introduction
Rosenquist R; Davi F; Stamatopoulos K
Review: SEMINARS IN CANCER BIOLOGY. 2013;23(6):399-409
Antigen selection in B-cell lymphomas-Tracing the evidence
Sutton L-A; Agathangelidis A; Belessi C; Darzentas N; Davi F; Ghia P; Rosenquist R; Stamatopoulos K
Review: LEUKEMIA & LYMPHOMA. 2013;54(11):2351-2364
Prognostic markers and their clinical applicability in chronic lymphocytic leukemia: where do we stand?
Rosenquist R; Cortese D; Bhoi S; Mansouri L; Gunnarsson R
Review: LEUKEMIA & LYMPHOMA. 2013;54(8):1583-1590
Exploring the genetic landscape in chronic lymphocytic leukemia using high-resolution technologies
Gunnarsson R; Mansouri L; Rosenquist R
Review: EPIGENETICS. 2013;8(2):138-148
Uncovering the DNA methylome in chronic lymphocytic leukemia
Cahill N; Rosenquist R
Letter: LEUKEMIA. 2013;27(2):510-512
Whole-genome-amplified DNA as a source for mutational analysis underestimates the frequency of mutations in pediatric acute myeloid leukemia
Rosenquist R; Ehrencrona H; Hasle H; Palle J; Kanduri M
Letter: LEUKEMIA. 2013;27(2):512-514
NOTCH1 and SF3B1 mutations can be added to the hierarchical prognostic classification in chronic lymphocytic leukemia
Mansouri L; Cahill N; Gunnarsson R; Smedby KE; Tjonnfjord E; Hjalgrim H; Juliusson G; Geisler C; Rosenquist R
Letter: LEUKEMIA. 2012;26(5):1127-1131
Antigen receptor stereotypy across B-cell lymphoproliferations: the case of IGHV4-59/IGKV3-20 receptors with rheumatoid factor activity
Kostareli E; Gounari M; Janus A; Murray F; Brochet X; Giudicelli V; Pospisilova S; Oscier D; Foroni L; di Celle PF; Tichy B; Pedersen LB; Jurlander J; Ponzoni M; Kouvatsi A; Anagnostopoulos A; Thompson K; Darzentas N; Lefranc M-P; Belessi C; Rosenquist R; Davi F; Ghia P; Stamatopoulos K
Review: EXPERT REVIEW OF HEMATOLOGY. 2012;5(1):69-79
RNA-based markers as prognostic factors in chronic lymphocytic leukemia
Sevov M; Rosenquist R; Mansouri L
Letter: BLOOD. 2012;119(4):1087-1088
High ERG gene expression is an unfavorable prognostic marker in pediatric acute myeloid leukemia Response
Staffas A; Kanduri M; Hovland R; Rosenquist R; Ommen HB; Abrahamsson J; Forestier E; Jahnukainen K; Jonsson OG; Zeller B; Palle J; Lonnerholm G; Hasle H; Ehrencrona H; Palmqvist L
Letter: LEUKEMIA. 2012;26(1):170-172
Coexistence of trisomies of chromosomes 12 and 19 in chronic lymphocytic leukemia occurs exclusively in the rare IgG-positive variant
Ibbotson R; Athanasiadou A; Sutton L-A; Davis Z; Gardiner A; Baliakas P; Gunnarsson R; Anagnostopoulos A; Juliusson G; Rosenquist R; Oscier D; Stamatopoulos K
Letter: LEUKEMIA. 2011;25(12):1904-1908
Impact of TP53 mutation and 17p deletion in mantle cell lymphoma
Halldorsdottir AM; Lundin A; Murray F; Mansouri L; Knuutila S; Sundstrom C; Laurell A; Ehrencrona H; Sander B; Rosenquist R
Review: SEMINARS IN CANCER BIOLOGY. 2011;21(5):299-307
Unlocking the secrets of immunoglobulin receptors in mantle cell lymphoma: Implications for the origin and selection of the malignant cells
Agathangelidis A; Hadzidimitriou A; Rosenquist R; Stamatopoulos K
Letter: LEUKEMIA & LYMPHOMA. 2011;52(6):1146-1149
LMO2 protein expression predicts survival in patients with rheumatoid arthritis and diffuse large B-cell lymphoma
Baecklund E; Backlin C; Mansouri M; Klareskog L; Askling J; Iliadou AN; Enblad G; Lossos IS; Natkunam Y; Rosenquist R
Review: SEMINARS IN CANCER BIOLOGY. 2010;20(6):400-409
Antigens in chronic lymphocytic leukemia-Implications for cell origin and leukemogenesis
Rosen A; Murray F; Evaldsson C; Rosenquist R
Letter: LEUKEMIA. 2010;24(1):211-215
Large but not small copy-number alterations correlate to high-risk genomic aberrations and survival in chronic lymphocytic leukemia: a high-resolution genomic screening of newly diagnosed patients
Gunnarsson R; Isaksson A; Mansouri M; Goransson H; Jansson M; Cahill N; Rasmussen M; Staaf J; Lundin J; Norin S; Buhl AM; Smedby KE; Hjalgrim H; Karlsson K; Jurlander J; Juliusson G; Rosenquist R
Letter: LEUKEMIA & LYMPHOMA. 2009;50(5):829-830
Infrequent occurrence of PIK3CA mutations in chronic lymphocytic leukemia
Marincevic M; Tobin G; Rosenquist R
Editorial comment: JOURNAL OF INTERNAL MEDICINE. 2008;264(6):512-513
Introduction: the role of inflammation, autoimmune disease and infectious agents in development of leukaemia and lymphoma
Rosenquist R
Letter: BLOOD. 2008;111(12):5756-5757
Or both? Response
Roos G; Rosenquist R; Stilgenbauer S
Review: LEUKEMIA & LYMPHOMA. 2008;49(6):1042-1049
Molecular genetic characterization reveals new subsets of mantle cell lymphoma
Thelander EF; Rosenquist R
Review: GENES CHROMOSOMES & CANCER. 2008;47(2):149-158
Clinical and cytogenetic features of pediatric dic(9;20)(p13.2;q11.2)-positive B-Cell precursor acute lymphoblastic leukemias:: A nordic series of 24 cases and review of the literature
Forestier E; Gauffin F; Andersen MK; Autio K; Borgstrom G; Golovleva I; Gustafsson B; Heim S; Heinonen K; Heyman M; Hovland R; Johannsson JH; Kerndrup G; Rosenquist R; Schoumans J; Swolin B; Johansson B; Nordgren A
Letter: LEUKEMIA. 2008;22(1):212-214
Determination of IGHV gene mutational status in chronic lymphocytic leukemia: bioinformatics advances meet clinical needs
Davi F; Rosenquist R; Ghia P; Belessi C; Stamatopoulos K
Letter: LEUKEMIA. 2007;21(12):2539-2540
Reply to 'Male preponderance in chronic lymphocytic leukemia utilizing IGHV1-69' When size of the sample matters
Ghia P; Belessi C; Davi F; Rosenquist R; Stamatopoulos K
Review: GENES CHROMOSOMES & CANCER. 2007;46(5):440-450
Cytogenetic patterns in ETV6/RUNXI-positive pediatric B-cell precursor acute lymphoblastic leukemia:: A Nordic series of 245 cases and review of the literature
Forestier E; Andersen MK; Autio K; Blennow E; Borgstrom G; Golovleva I; Heim S; Heinonen K; Hovland R; Johannsson JH; Kerndrup G; Nordgren A; Rosenquist R; Swolin B; Johansson B
Editorial comment: LEUKEMIA. 2007;21(1):1-3
ERIC recommendations on IGHV gene mutational status analysis in chronic lymphocytic leukemia
Ghia P; Stamatopoulos K; Belessi C; Moreno C; Stilgenbauer S; Stevenson F; Davi F; Rosenquist R
Letter: BLOOD. 2006;108(10):3623-3624
Subtype preference of the BCL6_397G/C polymorphism in germinal-center and non-germinal-center subtypes of diffuse large B-cell lymphoma
Berglund M; Amini R-M; Book M; Rosenquist R; Roos G; Thunberg U
Review: HEMATOLOGICAL ONCOLOGY. 2006;24(1):7-13
What is the current evidence for antigen involvement in the development of chronic lymphocytic leukemia?
Tobin G; Rosén A; Rosenquist R
Letter: BLOOD. 2005;105(12):4894-4895
The interleukin-10 gene promoter polymorphism (-1082) does not correlate with clinical outcome in diffuse large B-cell lymphoma
Berglund M; Thunberg U; Roos G; Rosenquist R; Enblad G
Letter: LEUKEMIA. 2005;19(5):871-873
Mcl-1 gene promoter insertions do not correlate with disease outcome, stage or V_H gene mutation status in chronic lymphocytic leukaemia
Tobin G; Skogsberg Å; Thunberg U; Laurell A; Åleskog A; Merup M; Sundström C; Roos G; Nilsson K; Rosenquist R
Letter: LEUKEMIA. 2005;19(3):464
Absence of H2AX gene mutations in B-cell leukemias and lymphomas
Walsh SH; Rosenquist R
Review: MEDICAL ONCOLOGY. 2005;22(4):327-341
Immunoglobulin gene analysis of mature B-cell malignancies
Walsh SH; Rosenquist R
Review: MEDICAL ONCOLOGY. 2005;22(3):217-228
Prognostic usage of V_H gene mutation status and its surrogate markers and the role of antigen selection in chronic lymphocytic leukemia
Tobin G; Rosenquist R
Letter: BRITISH JOURNAL OF HAEMATOLOGY. 2004;125(6):815-817
Association of the 1513C polymorphism in the P2X7 gene with familial forms of chronic lymphocytic leukaemia
Dao-Ung LP; Fuller SJ; Sluyter R; SkarRatt KK; Thunberg U; Tobin G; Byth K; Ban M; Rosenquist R; Stewart GJ; Wiley JS
Review: CURRENT OPINION IN RHEUMATOLOGY. 2004;16(3):254-261
Rheumatoid arthritis and malignant lymphomas
Baecklund E; Askling J; Rosenquist R; Ekbom A; Klareskog L
Letter: LANCET. 2003;361(9367):1478-1479
P2X7 polymorphism and chronic lymphocytic leukaemia -: Reply
Thunberg U; Tobin G; Johnson A; Enblad G; Rosenquist R
Letter: BLOOD. 2002;100(3):1098-1099
IgV_H3-21 gene usage in chronic lymphocytic leukemia
Tobin G; Thunberg U; Johnson A; Söderberg O; Botling J; Enblad G; Sällström J; Sundström C; Roos G; Rosenquist R
Letter: BLOOD. 2001;97(6):1892-1894
CD38 expression is a poor predictor for V_H gene mutational status and prognosis in chronic lymphocytic leukemia
Thunberg U; Johnson A; Roos G; Thöm I; Tobin G; Sällström J; Sundström C; Rosenquist R
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Forskningsbidrag

The molecular landscape of chronic lymphocytic leukemia
Swedish Cancer Society
1 January 2018
The molecular landscape of chronic lymphocytic leukemia
Swedish Cancer Society
1 January 2017
The molecular landscape of chronic lymphocytic leukemia
Swedish Cancer Society
1 January 2016
Characterization of the molecular landscape in chronic lymphocytic leukemia
Swedish Cancer Society
1 January 2015
Characterization of the molecular landscape in chronic lymphocytic leukemia
Swedish Cancer Society
1 January 2014

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Nyheter från externa medier

KNUT OCH ALICE WALLENBERGS STIFTELSE. 2018
Förfinar kunskapen om leukemi