Richard Rosenquist Brandell | Karolinska Institutet

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About me

Richard Rosenquist Brandell was recently appointed Professor of Clinical Genetics at the Department of Molecular Medicine and Surgery, Karolinska Institutet and Senior Physician in Clinical Genetics at Karolinska University Hospital, Sweden. He received his medical degree (1996) and PhD degree (1998) at Umeå University, Sweden, undertook a postdoctoral period at the Department of Pathology, Frankfurt am Main, Germany, and became specialist in Clinical Genetics 2004. Richard Rosenquist Brandell started his own research group at Uppsala University in 2000, focusing on molecular characterization of lymphoid malignancies, and his group rapidly became internationally renowned. He became Professor of Molecular Hematology in 2007 at the Department of Immunology, Genetics and Pathology, Uppsala University. He has initiated and led the SciLifeLab Clinical Genomics Facility in Uppsala between 2013-2017 and is currently Platform Director for the national Diagnostics Development Platform within SciLifeLab. More recently, he is coordinating the Genomics Medicine Sweden initiative that aims to build a new type of infrastructure within Swedish healthcare that implements precision medicine at a national level.

By employing a translational approach and utilizing cutting‐edge molecular tools, including next-generation sequencing technologies, Richard Rosenquist Brandell has made outstanding contributions to our understanding of the mechanisms behind the development of chronic lymphocytic leukemia (CLL), the most common adult leukemia. His studies have identified novel prognostic and predictive markers, defined new clinically relevant CLL subgroups, as well as provided significantly improved risk stratification at the individual patient level. Even more importantly, Rosenquist Brandell’s team has presented compelling evidence for a role of antigens (both autoantigens and microbial antigens) in the pathogenesis of CLL, which has generated great interest internationally. He has also built competitive networks at the national, European and international level. He is one of five founding members of an eminent European network of CLL researcher with an impressive combined cohort of more than 34, 000 CLL patients from 24 academic institutions.

Research

Research group leader of the group Clinical Genetics

Teaching

Richard Rosenquist Brandell has successfully supervised 23 PhD students as well as seven postdocs, and his research has resulted in more than 200 peer-reviewed papers. He was recently selected as Wallenberg Clinical Scholars 2017 by the Knut and Alice Wallenberg Foundation.

Articles

Article: JOURNAL OF MEDICAL ECONOMICS. 2024;27(1):1053-1060
Micro-costing of genetic diagnostics in acute leukemia in Sweden: from standard-of-care to whole-genome sequencing
Thangavelu T; Wirta V; Orsmark-Pietras C; Cavelier L; Fioretos T; Barbany G; Olsson-Arvidsson L; Pandzic T; Staffas A; Rosenquist R; Levin L-A
Article: LEUKEMIA. 2024;38(11):2429-2442
The non-canonical BAF chromatin remodeling complex is a novel target of spliceosome dysregulation in SF3B1-mutated chronic lymphocytic leukemia
Hagerstrand D; Oder B; Cortese D; Qu Y; Binzer-Panchal A; Osterholm C; Del Peso Santos T; Rabbani L; Asl HF; Skaftason A; Ljungstrom V; Lundholm A; Koutroumani M; Haider Z; Jylha C; Mollstedt J; Mansouri L; Plevova K; Agathangelidis A; Scarfo L; Armand M; Muggen AF; Kay NE; Shanafelt T; Rossi D; Orre LM; Pospisilova S; Barylyuk K; Davi F; Vesterlund M; Langerak AW; Lehtio J; Ghia P; Stamatopoulos K; Sutton L-A; Rosenquist R
Article: NATURE GENETICS. 2024;:2287-2294
Pushing the boundaries of rare disease diagnostics with the help of the first Undiagnosed Hackathon.
Delgado-Vega AM; Cederroth H; Taylan F; Ekholm K; Ek M; Thonberg H; Jemt A; Nilsson D; Eisfeldt J; Bilgrav Saether K; Höijer I; Akgun-Dogan O; Asano Y; Barakat TS; Batkovskyte D; Baynam G; Bodamer O; Chetruengchai W; Corcoran P; Couse M; Danis D; Demidov G; Dohi E; Erhardsson M; Fernandez-Luna L; Fujiwara T; Garg N; Giugliani R; Gonzaga-Jauregui C; Grigelioniene G; Groza T; Gunnarsson C; Hammarsjö A; Hammond CK; Hatirnaz Ng Ö; Hesketh S; Hettiarachchi D; Johansson Soller M; Kirmani UA; Kjellberg M; Kvarnung M; Kvlividze O; Lagerstedt-Robinson K; Lasko P; Lassmann T; Lau LYS; Laurie S; Lim WK; Liu Z; Lysenkova Wiklander M; Makay P; Maiga AB; Maya-González C; Meyn MS; Neethiraj R; Nigro V; Nordgren F; Nordlund J; Orrsjö S; Ottosson J; Ozbek U; Özdemir Ö; Partin C; Pearce DA; Peck R; Pedersen A; Pettersson M; Pongpanich M; Posada de la Paz M; Ramani A; Romero JA; Romero VI; Rosenquist R; Saw AM; Spencer M; Stattin E-L; Srichomthong C; Tapia-Paez I; Taruscio D; Taylor JP; Tkemaladze T; Tully I; Tümer Z; van Zelst-Stams WAG; Verloes A; Västerviga E; Wang S; Yang R; Yamamoto S; Yépez VA; Zhang Q; Shotelersuk V; Wiafe SA; Alanay Y; Botto LD; Kirmani S; Lumaka A; Palmer EE; Puri RD; Wirta V; Lindstrand A; Buske OJ; Cederroth M; Nordgren A
Article: EJHAEM. 2024;5(5):998-1004
Medical history and lifestyle factors have limited impact on time-to-first-treatment in patients with chronic lymphocytic leukemia
Glimelius I; Kleinstern G; Robinson DP; Mansouri L; Rostgaard K; Hjalgrim H; Niemann CU; Mattsson M; Rabe KG; Hampel PJ; Parikh SA; Rosenquist R; Cerhan JR; Slager SL; Smedby KE
Article: HEALTH INFORMATICS JOURNAL. 2024;30(4):14604582241290725
Smart variant filtering - A blueprint solution for massively parallel sequencing-based variant analysis
Brahimllari O; Eloranta S; Georgii-Hemming P; Haider Z; Koch S; Krstic A; Skarp FP; Rosenquist R; Smedby KE; Taylan F; Thorvaldsdottir B; Wirta V; Wasterlid T; Boman M
Article: GENES CHROMOSOMES AND CANCER. 2024;63(7):e23257
Precision Diagnostics in Myeloid Malignancies: Development and Validation of a National Capture-Based Gene Panel
Orsmark-Pietras C; Lyander A; Ladenvall C; Hallstrom B; Staffas A; Awier H; Krstic A; Baliakas P; Barbany G; Hakansson CB; Gellerbring A; Hagstrom A; Hellstrom-Lindberg E; Juliusson G; Lazarevic V; Munters A; Pandzic T; Wadelius M; As J; Fogelstrand L; Wirta V; Rosenquist R; Cavelier L; Fioretos T
Article: JOURNAL OF INTERNAL MEDICINE. 2024;295(6):785-803
High-throughput molecular assays for inclusion in personalised oncology trials - State-of-the-art and beyond
Edsjo A; Russnes HG; Lehtio J; Tamborero D; Hovig E; Stenzinger A; Rosenquist R
Article: LEUKEMIA. 2024;38(6):1287-1298
IκBε deficiency accelerates disease development in chronic lymphocytic leukemia
Bordini J; Lenzi C; Frenquelli M; Morabito A; Pseftogas A; Belloni D; Mansouri L; Tsiolas G; Perotta E; Ranghetti P; Gandini F; Genova F; Hagerstrand D; Gavriilidis G; Keisaris S; Pechlivanis N; Davi F; Kay NE; Langerak AW; Pospisilova S; Scarfo L; Makris A; Psomopoulos FE; Stamatopoulos K; Rosenquist R; Campanella A; Ghia P
Article: NATURE GENETICS. 2024;56(5):733-736
The 1+Million Genomes Minimal Dataset for Cancer
Riba M; Sala C; Culhane AC; Flobak A; Patocs A; Boye K; Plevova K; Pospisilova S; Gandolfi G; Morelli MJ; Bucci G; Edsjo A; Lassen U; Al-Shahrour F; Lopez-Bigas N; Hovland R; Cuppen E; Valencia A; Poirel HA; Rosenquist R; Scollen S; Marquez JA; Belien J; De Nicolo A; De Maria R; Torrents D; Tonon G
Article: THE LANCET REGIONAL HEALTH. EUROPE. 2024;39:100881
Diagnostic yield and clinical impact of germline sequencing in children with CNS and extracranial solid tumors - a nationwide, prospective Swedish study
Tesi B; Robinson KL; Abel F; Stahl TDD; Orrsjoe S; Poluha A; Hellberg M; Wessman S; Samuelsson S; Frisk T; Vogt H; Henning K; Sabel M; Ek T; Pal N; Nyman P; Giraud G; Wille J; Pronk CJ; Noren-Nystroem U; Borssen M; Fili M; Stalhammar G; Herold N; Tettamanti G; Maya-Gonzalez C; Arvidsson L; Rosen A; Ekholm K; Kuchinskaya E; Hallbeck A-L; Nordling M; Palmebaeck P; Kogner P; Smoler GK; Laehteenmaeki P; Fransso S; Martinsson T; Shamik A; Mertens F; Rosenquist R; Wirta V; Tham E; Grillner P; Sandgren J; Ljungman G; Gisselsson D; Taylan F; Nordgren A
Article: JOURNAL OF CLINICAL ONCOLOGY. 2024;42(4):452-466
Genetic Characterization of Primary Mediastinal B-Cell Lymphoma: Pathogenesis and Patient Outcomes
Noerenberg D; Briest F; Hennch C; Yoshida K; Hablesreiter R; Takeuchi Y; Ueno H; Staiger AM; Ziepert M; Asmar F; Locher BN; Toth E; Weber T; Amini R-M; Klapper W; Bouzani M; Poeschel V; Rosenwald A; Held G; Campo E; Ishaque N; Stamatopoulos K; Kanellis G; Anagnostopoulos I; Bullinger L; Goldschmidt N; Zinzani PL; Boedoer C; Rosenquist R; Vassilakopoulos TP; Ott G; Ogawa S; Damm F
Article: LEUKEMIA. 2023;37(11):2237-2249
Frequent ZNF217 mutations lead to transcriptional deregulation of interferon signal transduction via altered chromatin accessibility in B cell lymphoma
Briest F; Noerenberg D; Hennch C; Yoshida K; Hablesreiter R; Nimo J; Sasca D; Kirchner M; Mansouri L; Inoue Y; Wiegand L; Staiger AM; Casadei B; Korkolopoulou P; Weiner J; Lopez-Guillermo A; Warth A; Schneider T; Nagy A; Klapper W; Hummel M; Kanellis G; Anagnostopoulos I; Mertins P; Bullinger L; Rosenquist R; Vassilakopoulos TP; Ott G; Ogawa S; Damm F
Article: HAEMATOLOGICA. 2023;108(10):2664-2676
Subgroup-specific gene expression profiles and mixed epistasis in chronic lymphocytic leukemia.
Lütge A; Lu J; Hüllein J; Walther T; Sellner L; Wu B; Rosenquist R; Oakes CC; Dietrich S; Huber W; Zenz T
Article: GENES CHROMOSOMES AND CANCER. 2023;62(9):557-563
Real-world data for precision cancer medicine-A European perspective.
Christopoulos P; Schlenk R; Kazdal D; Blasi M; Lennerz J; Shah R; Budczies J; Malek N; Fröhling S; Rosenquist R; Schirmacher P; Bozorgmehr F; Kuon J; Reck M; Thomas M; Stenzinger A
Article: JOURNAL OF CLINICAL INVESTIGATION. 2023;133(13):e166070
Tumor-activated lymph node fibroblasts suppress T cell function in diffuse large B cell lymphoma
Apollonio B; Spada F; Petrov N; Cozzetto D; Papazoglou D; Jarvis P; Kannambath S; Terranova-Barberio M; Amini R-M; Enblad G; Graham C; Benjamin R; Phillips E; Ellis R; Nuamah R; Saqi M; Calado DP; Rosenquist R; Sutton LA; Salisbury J; Zacharioudakis G; Vardi A; Hagner PR; Gandhi AK; Bacac M; Claus C; Umana P; Jarrett RF; Klein C; Deutsch A; Ramsay AG
Article: CURRENT RESEARCH IN TRANSLATIONAL MEDICINE. 2023;71(3):103401
Establishment and characterization of a novel breast implant-associated anaplastic large cell lymphoma cell line and PDX model (BIA-XR1) with a unique KRAS mutation
Xagoraris I; Stathopoulou K; Aulerio RD; He M; Ketscher A; Jatta K; de Flon FH; Barbany G; Rosenquist R; Westerberg LS; Rassidakis GZ
Article: BLOOD ADVANCES. 2023;7(12):2794-2806
BTK and PLCG2 remain unmutated in one-third of patients with CLL relapsing on ibrutinib
Bonfiglio S; Sutton L-A; Ljungstrom V; Capasso A; Pandzic T; Westrom S; Foroughi-Asl H; Skaftason A; Gellerbring A; Lyander A; Gandini F; Gaidano G; Trentin L; Bonello L; Reda G; Bodor C; Stavroyianni N; Tam CS; Marasca R; Forconi F; Panayiotidis P; Ringshausen I; Jaksic O; Frustaci AM; Iyengar S; Coscia M; Mulligan SP; Ysebaert L; Strugov V; Pavlovsky C; Walewska R; Osterborg A; Cortese D; Ranghetti P; Baliakas P; Stamatopoulos K; Scarfo L; Rosenquist R; Ghia P
Article: JCO PRECISION ONCOLOGY. 2023;7:e2300039
Diagnostic Yield From a Nationwide Implementation of Precision Medicine for all Children With Cancer
Wadensten E; Wessman S; Abel F; De Stahl TD; Tesi B; Pietras CO; Arvidsson L; Taylan F; Fransson S; Vogt H; Poluha A; Pradhananga S; Hellberg M; Lagerstedt-Robinson K; Raj Somarajan P; Samuelsson S; Orrsjo S; Maqbool K; Henning K; Strid T; Ek T; Fagman H; Bontell TO; Martinsson T; Puls F; Kogner P; Wirta V; Pronk CJ; Wille J; Rosenquist R; Nister M; Mertens F; Sabel M; Noren-Nystrom U; Grillner P; Nordgren A; Ljungman G; Sandgren J; Gisselsson D
Article: LAKARTIDNINGEN. 2023;120:22139
Precisionsmedicin kräver samverkan och långsiktighet.
Edsjö A; Fioretos T; Rosenquist R
Article: CANCERS. 2023;15(7):1972
Simultaneous Ultra-Sensitive Detection of Structural and Single Nucleotide Variants Using Multiplex Droplet Digital PCR in Liquid Biopsies from Children with Medulloblastoma
Arthur C; Jylha C; de Stahl TD; Shamikh A; Sandgren J; Rosenquist R; Nordenskjold M; Harila A; Barbany G; Sandvik U; Tham E
Article: LEUKEMIA. 2023;37(2):339-347
Different prognostic impact of recurrent gene mutations in chronic lymphocytic leukemia depending on IGHV gene somatic hypermutation status: a study by ERIC in HARMONY
Mansouri L; Thorvaldsdottir B; Sutton L-A; Karakatsoulis G; Meggendorfer M; Parker H; Nadeu F; Brieghel C; Laidou S; Moia R; Rossi D; Catherwood M; Kotaskova J; Delgado J; Rodriguez-Vicente AE; Benito R; Rigolin GM; Bonfiglio S; Scarfo L; Mattsson M; Davis Z; Gogia A; Rani L; Baliakas P; Foroughi-Asl H; Jylha C; Skaftason A; Rapado I; Miras F; Martinez-Lopez J; de la Serna J; Rivas JMH; Thornton P; Larrayoz MJ; Calasanz MJ; Fesus V; Matrai Z; Bodor C; Smedby KE; Espinet B; Puiggros A; Gupta R; Bullinger L; Bosch F; Tazon-Vega B; Baran-Marszak F; Oscier D; N'Guyen-Khac F; Zenz T; Terol MJ; Cuneo A; Hernandez-Sanchez M; Pospisilova S; Mills K; Gaidano G; Niemann CU; Campo E; Strefford JC; Ghia P; Stamatopoulos K; Rosenquist R
Article: FRONTIERS IN ONCOLOGY. 2023;13:1097942
T cell receptor gene repertoire profiles in subgroups of patients with chronic lymphocytic leukemia bearing distinct genomic aberrations
Vlachonikola E; Pechlivanis N; Karakatsoulis G; Sofou E; Gkoliou G; Jeromin S; Stavroyianni N; Ranghetti P; Scarfo L; Osterholm C; Mansouri L; Notopoulou S; Siorenta A; Anagnostopoulos A; Ghia P; Haferlach C; Rosenquist R; Psomopoulos F; Kouvatsi A; Baliakas P; Stamatopoulos K; Chatzidimitriou A
Article: FRONTIERS IN ONCOLOGY. 2023;13:1217712
Feasibility to use whole-genome sequencing as a sole diagnostic method to detect genomic aberrations in pediatric B-cell acute lymphoblastic leukemia
Rezayee F; Eisfeldt J; Skaftason A; Ofverholm I; Sayyab S; Syvanen AC; Maqbool K; Lilljebjorn H; Johansson B; Olsson-Arvidsson L; Pietras CO; Staffas A; Palmqvist L; Fioretos T; Cavelier L; Fogelstrand L; Nordlund J; Wirta V; Rosenquist R; Barbany G
Article: FRONTIERS IN ONCOLOGY. 2023;13:1176698
Whole-genome informed circulating tumor DNA analysis by multiplex digital PCR for disease monitoring in B-cell lymphomas: a proof-of-concept study
Haider Z; Wasterlid T; Spangberg LD; Rabbani L; Jylha C; Thorvaldsdottir B; Skaftason A; Awier HN; Krstic A; Gellerbring A; Lyander A; Hagglund M; Jeggari A; Rassidakis G; Sonnevi K; Sander B; Rosenquist R; Tham E; Smedby KE
Article: JCO PRECISION ONCOLOGY. 2022;6:e2200245
Implementation of Whole-Genome and Transcriptome Sequencing Into Clinical Cancer Care.
Cuppen E; Elemento O; Rosenquist R; Nikic S; IJzerman M; Zaleski ID; Frederix G; Levin L-Å; Mullighan CG; Buettner R; Pugh TJ; Grimmond S; Caldas C; Andre F; Custers I; Campo E; van Snellenberg H; Schuh A; Nakagawa H; von Kalle C; Haferlach T; Fröhling S; Jobanputra V
Article: BLOOD. 2022;140(21):2193-2227
Genomic profiling for clinical decision making in lymphoid neoplasms
de Leval L; Alizadeh AA; Bergsagel PL; Campo E; Davies A; Dogan A; Fitzgibbon J; Horwitz SM; Melnick AM; Morice WG; Morin RD; Nadel B; Pileri SA; Rosenquist R; Rossi D; Salaverria I; Steidl C; Treon SP; Zelenetz AD; Advani RH; Allen CE; Ansell SM; Chan WC; Cook JR; Cook LB; D'Amore F; Dirnhofer S; Dreyling M; Dunleavy K; Feldman AL; Fend F; Gaulard P; Ghia P; Gribben JG; Hermine O; Hodson DJ; Hsi ED; Inghirami G; Jaffe ES; Karube K; Kataoka K; Klapper W; Kim WS; King RL; Ko YH; LaCasce AS; Lenz G; Martin-Subero JI; Piris MA; Pittaluga S; Pasqualucci L; Quintanilla-Martinez L; Rodig SJ; Rosenwald A; Salles GA; San-Miguel J; Savage KJ; Sehn LH; Semenzato G; Staudt LM; Swerdlow SH; Tam CS; Trotman J; Vose JM; Weigert O; Wilson WH; Winter JN; Wu CJ; Zinzani PL; Zucca E; Bagg A; Scott DW
Article: NATURE COMMUNICATIONS. 2022;13(1):6226
Proteogenomics refines the molecular classification of chronic lymphocytic leukemia
Herbst SA; Vesterlund M; Helmboldt AJ; Jafari R; Siavelis I; Stahl M; Schitter EC; Liebers N; Brinkmann BJ; Czernilofsky F; Roider T; Bruch P-M; Iskar M; Kittai A; Huang Y; Lu J; Richter S; Mermelekas G; Umer HM; Knoll M; Kolb C; Lenze A; Cao X; Osterholm C; Wahnschaffe L; Herling C; Scheinost S; Ganzinger M; Mansouri L; Kriegsmann K; Kriegsmann M; Anders S; Zapatka M; Del Poeta G; Zucchetto A; Bomben R; Gattei V; Dreger P; Woyach J; Herling M; Muller-Tidow C; Rosenquist R; Stilgenbauer S; Zenz T; Huber W; Tausch E; Lehtioe J; Dietrich S
Article: SEMINARS IN CANCER BIOLOGY. 2022;84:170-183
Precision diagnostics in lymphomas-Recent developments and future directions
Mansouri L; Thorvaldsdottir B; Laidou S; Stamatopoulos K; Rosenquist R
Article: SEMINARS IN CANCER BIOLOGY. 2022;84:242-254
Trailblazing precision medicine in Europe: A joint view by Genomic Medicine Sweden and the Centers for Personalized Medicine, ZPM, in Germany
Stenzinger A; Edsjoe A; Ploeger C; Friedman M; Frohling S; Wirta V; Seufferlein T; Botling J; Duyster J; Akhras M; Thimme R; Fioretos T; Bitzer M; Cavelier L; Schirmacher P; Malek N; Rosenquist R
Article: BLOOD. 2022;139(22):3340-3344
Secondary resistance to idelalisib is characterized by upregulation of IGF1R rather than by MAPK/ERK pathway mutations
Tausch E; Ljungstrom V; Agathangelidis A; Zapatka M; Scarfo L; Jebaraj BMC; Yosifov DY; Mueller A; Munugalavadla V; Degenhardt JD; Ghia P; Rosenquist R; Stilgenbauer S
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2022;108(5):369-378
Identifying patients with chronic lymphocytic leukemia without need of treatment: End of endless watch and wait?
Brieghel C; Galle V; Agius R; Da Cunha-Bang C; Andersen MA; Vlummens P; Mattsson M; Rosenquist R; Smedby KE; Herling CD; Bahlo J; Hallek M; Lundgren JD; Offner F; Niemann CU
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2022;197(4):431-441
International validation of the EORTC QLQ-CLL17 questionnaire for assessment of health-related quality of life for patients with chronic lymphocytic leukaemia
Oerlemans S; Efficace F; Kieffer JM; Kyriakou C; Xochelli A; Levedahl K; Petranovic D; Borges FC; Bredart A; Shamieh O; Gziskevicius L; Lehmann J; Scholz CW; Caocci G; Molica S; Stamatopoulos K; Panteliadou A-K; Papaioannou M; Alrjoob W; Baliakas P; Rosenquist R; Malak S; Miranda A; Cocks K; van de Poll-Franse L
Article: BLOOD ADVANCES. 2022;6(8):2657-2666
Incidence and time trends of second primary malignancies after non-Hodgkin lymphoma: a Swedish population-based study
Joelsson J; Wasterlid T; Rosenquist R; Jakobsen LH; El-Galaly TC; Smedby KE; Eloranta S
Article: FRONTIERS IN ONCOLOGY. 2022;12:897280
Impact of the Types and Relative Quantities of IGHV Gene Mutations in Predicting Prognosis of Patients With Chronic Lymphocytic Leukemia
Kaufman M; Yan X-J; Li W; Ghia EM; Langerak AW; Rassenti LZ; Belessi C; Kay NE; Davi F; Byrd JC; Pospisilova S; Brown JR; Catherwood M; Davis Z; Oscier D; Montillo M; Trentin L; Rosenquist R; Ghia P; Barrientos JC; Kolitz JE; Allen SL; Rai KR; Stamatopoulos K; Kipps TJ; Neuberg D; Chiorazzi N
Article: FRONTIERS IN ONCOLOGY. 2022;12:899325
Patient-Specific Assays Based on Whole-Genome Sequencing Data to Measure Residual Disease in Children With Acute Lymphoblastic Leukemia: A Proof of Concept Study
Arthur C; Rezayee F; Mogensen N; Saft L; Rosenquist R; Nordenskjold M; Harila-Saari A; Tham E; Barbany G
Article: FRONTIERS IN MEDICINE. 2022;9:842507
A Study Protocol for Validation and Implementation of Whole-Genome and -Transcriptome Sequencing as a Comprehensive Precision Diagnostic Test in Acute Leukemias
Berglund E; Barbany G; Orsmark-Pietras C; Fogelstrand L; Abrahamsson J; Golovleva I; Hallbook H; Hoglund M; Lazarevic V; Levin L-A; Nordlund J; Noren-Nystrom U; Palle J; Thangavelu T; Palmqvist L; Wirta V; Cavelier L; Fioretos T; Rosenquist R; Clinical GPSGMS
Article: GENES CHROMOSOMES AND CANCER. 2022;61(1):27-36
Transcriptome sequencing of archived lymphoma specimens is feasible and clinically relevant using exome capture technology
Skaftason A; Qu Y; Abdulla M; Nordlund J; Berglund M; Ednersson SB; Andersson P-O; Enblad G; Amini R-M; Rosenquist R; Mansouri L
Article: BMJ OPEN. 2021;11(11):e050256
MyPal ADULT study protocol: a randomised clinical trial of the MyPal ePRO-based early palliative care system in adult patients with haematological malignancies
Scarfo L; Karamanidou C; Doubek M; Garani-Papadatos T; Didi J; Pontikoglou C; Ling J; Payne C; Papadaki HA; Rosenquist R; Stavroyianni N; Payne S; Ghia P; Natsiavas P; Maramis C; Stamatopoulos K
Article: BLOOD ADVANCES. 2021;5(13):2788-2792
RPS15 mutations rewire RNA translation in chronic lymphocytic leukemia
Ntoufa S; Gerousi M; Laidou S; Psomopoulos F; Tsiolas G; Moysiadis T; Papakonstantinou N; Mansouri L; Anagnostopoulos A; Stavrogianni N; Pospisilova S; Plevova K; Makris AM; Rosenquist R; Stamatopoulos K
Article: HEMATOLOGICAL ONCOLOGY. 2021;39:73-77
Molecular diagnostics and reporting in lymphoid malignancies: Current status and beyond
Rosenquist R
Article: LAKARTIDNINGEN. 2021;118:21023
[Genomic Medicine Sweden - a national initiative for the broad introduction of precision medicine in Swedish healthcare].
Edsjö A; Friedman M; Rosenquist R
Article: LAKARTIDNINGEN. 2021;118:20186
[Precision diagnostics and therapy in hematological malignancies].
Hellström Lindberg E; Cavelier L; Cammenga J; Andersson P-O; Fioretos T; Rosenquist R
Article: BLOOD. 2021;137(14):1895-1904
Higher-order immunoglobulin repertoire restrictions in CLL: the illustrative case of stereotyped subsets 2 and 169
Gemenetzi K; Psomopoulos F; Carriles AA; Gounari M; Minici C; Plevova K; Sutton L-A; Tsagiopoulou M; Baliakas P; Pasentsis K; Anagnostopoulos A; Sandaltzopoulos R; Rosenquist R; Davi F; Pospisilova S; Ghia P; Stamatopoulos K; Degano M; Chatzidimitriou A
Article: BLOOD. 2021;137(10):1365-1376
Higher-order connections between stereotyped subsets: implications for improved patient classification in CLL
Agathangelidis A; Chatzidimitriou A; Gemenetzi K; Giudicelli V; Karypidou M; Plevova K; Davis Z; Yan X-J; Jeromin S; Schneider C; Pedersen LB; Tschumper RC; Sutton L-A; Baliakas P; Scarfo L; van Gastel EJ; Armand M; Tausch E; Biderman B; Baer C; Bagnara D; Navarro A; de Septenville AL; Guido V; Mitterbauer-Hohendanner G; Dimovski A; Brieghel C; Lawless S; Meggendorfer M; Brazdilova K; Ritgen M; Facco M; Tresoldi C; Visentin A; Patriarca A; Catherwood M; Bonello L; Sudarikov A; Vanura K; Roumelioti M; Francova HS; Moysiadis T; Veronese S; Giannopoulos K; Mansouri L; Karan-Djurasevic T; Sandaltzopoulos R; Bodor C; Fais F; Kater A; Panovska I; Rossi D; Alshemmari S; Panagiotidis P; Costeas P; Espinet B; Antic D; Foroni L; Montillo M; Trentin L; Stavroyianni N; Gaidano G; di Celle PF; Niemann C; Campo E; Anagnostopoulos A; Pott C; Fischer K; Hallek M; Oscier D; Stilgenbauer S; Haferlach C; Jelinek D; Chiorazzi N; Pospisilova S; Lefranc M-P; Kossida S; Langerak AW; Belessi C; Davi F; Rosenquist R; Ghia P; Stamatopoulos K
Article: HAEMATOLOGICA. 2021;106(3):682-691
Comparative analysis of targeted next-generation sequencing panels for the detection of gene mutations in chronic lymphocytic leukemia: an ERIC multi-center study
Sutton L-A; Ljungstrom V; Enjuanes A; Cortese D; Skaftason A; Tausch E; Kozubik KS; Nadeu F; Armand M; Malcikova J; Pandzic T; Forster J; Davis Z; Oscier D; Rossi D; Ghia P; Strefford JC; Pospisilova S; Stilgenbauer S; Davi F; Campo E; Stamatopoulos K; Rosenquist R
Article: FRONTIERS IN ONCOLOGY. 2021;11:740083
Consistent B Cell Receptor Immunoglobulin Features Between Siblings in Familial Chronic Lymphocytic Leukemia
Kolijn PM; Muggen AF; Ljungstrom V; Agathangelidis A; Wolvers-Tettero ILM; Beverloo HB; Pal K; Hengeveld PJ; Darzentas N; Hendriks RW; van Dongen JJM; Rosenquist R; Langerak AW
Article: HAEMATOLOGICA. 2021;106(1):87-97
Genomic arrays identify high-risk chronic lymphocytic leukemia with genomic complexity: a multicenter study
Leeksma AC; Baliakas P; Moysiadis T; Puiggros A; Plevova K; van der Kevie-Kersemaekers A-M; Posthuma H; Rodriguez-Vicente AE; Tran AN; Barbany G; Mansouri L; Gunnarsson R; Parker H; van den Berg E; Bellido M; Davis Z; Wall M; Scarpelli I; Osterborg A; Hansson L; Jarosova M; Ghia P; Poddighe P; Espinet B; Pospisilova S; Tam C; Ysebaert L; Nguyen-Khac F; Oscier D; Haferlach C; Schoumans J; Stevens-Kroef M; Eldering E; Stamatopoulos K; Rosenquist R; Strefford JC; Mellink C; Kater AP
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2020;105(6):779-785
Concordance in survival among first-degree relatives diagnosed with indolent lymphoid malignancies including chronic lymphocytic leukemia
Baecklund F; Ekberg S; Rosenquist R; Askling J; Eloranta S; Smedby KE
Article: HAEMATOLOGICA. 2020;105(11):2598-2607
Prognostic impact of prevalent chronic lymphocytic leukemia stereotyped subsets: analysis within prospective clinical trials of the German CLL Study Group
Jaramillo S; Agathangelidis A; Schneider C; Bahlo J; Robrecht S; Tausch E; Bloehdorn J; Hoechstetter M; Fischer K; Eichhorst B; Goede V; Hallek M; Doehner H; Rosenquist R; Ghia P; Stamatopoulos K; Stilgenbauer S
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2020;191(3):426-432
Risk-adapted bendamustine plus rituximab is a tolerable treatment alternative for elderly patients with chronic lymphocytic leukaemia: a regional real-world report on 141 consecutive Swedish patients
Mattsson A; Sylvan SE; Asklid A; Wiggh J; Winqvist M; Lundin J; Mansouri L; Rosenquist R; Johansson H; Osterborg A; Hansson L
Article: LEUKEMIA. 2020;34(10):2545-2551
Immunoglobulin gene analysis in chronic lymphocytic leukemia in the era of next generation sequencing
Davi F; Langerak AW; de Septenville AL; Kolijn PM; Hengeveld PJ; Chatzidimitriou A; Bonfiglio S; Sutton L-A; Rosenquist R; Ghia P; Stamatopoulos K
Article: BLOOD. 2020;135(21):1859-1869
International prognostic score for asymptomatic early-stage chronic lymphocytic leukemia
Condoluci A; di Bergamo LT; Langerbeins P; Hoechstetter MA; Herling CD; De Paoli L; Delgado J; Rabe KG; Gentile M; Doubek M; Mauro FR; Chiodin G; Mattsson M; Bahlo J; Cutrona G; Kotaskova J; Deambrogi C; Smedby KE; Spina V; Bruscaggin A; Wu W; Moia R; Bianchi E; Gerber B; Zucca E; Gillessen S; Ghielmini M; Cavalli F; Stussi G; Hess MA; Baumann TS; Neri A; Ferrarini M; Rosenquist R; Forconi F; Foa R; Pospisilova S; Morabito F; Stilgenbauer S; Doehner H; Parikh SA; Wierda WG; Montserrat E; Gaidano G; Hallek M; Rossi D
Article: CLINICAL CANCER RESEARCH. 2020;26(6):1507-1515
The Number of Signaling Pathways Altered by Driver Mutations in Chronic Lymphocytic Leukemia Impacts Disease Outcome
Brieghel C; da Cunha-Bang C; Yde CW; Schmidt AY; Kinalis S; Nadeu F; Andersen MA; Jacobsen LO; Andersen MK; Pedersen LB; Delgado J; Baumann T; Mattsson M; Mansouri L; Rosenquist R; Campo E; Nielsen FC; Niemann CU
Article: AMERICAN JOURNAL OF HEMATOLOGY. 2020;95(1):57-67
Cell-of-origin determined by both gene expression profiling and immunohistochemistry is the strongest predictor of survival in patients with diffuse large B-cell lymphoma
Abdulla M; Hollander P; Pandzic T; Mansouri L; Ednersson SB; Andersson P-O; Hultdin M; Fors M; Erlanson M; Degerman S; Petersen HM; Asmar F; Gronbaek K; Enblad G; Cavelier L; Rosenquist R; Amini R-M
Article: CLINICAL EPIGENETICS. 2019;11(1):177
DNA methylation profiles in chronic lymphocytic leukemia patients treated with chemoimmunotherapy
Tsagiopoulou M; Papakonstantinou N; Moysiadis T; Mansouri L; Ljungstrom V; Duran-Ferrer M; Malousi A; Queiros AC; Plevova K; Bhoi S; Kollia P; Oscier D; Anagnostopoulos A; Trentin L; Ritgen M; Pospisilova S; Stavroyianni N; Ghia P; Martin-Subero JI; Pott C; Rosenquist R; Stamatopoulos K
Article: EPIGENETICS. 2019;14(11):1125-1140
EZH2 upregulates the PI3K/AKT pathway through IGF1R and MYC in clinically aggressive chronic lymphocytic leukaemia
Kosalai ST; Morsy MHA; Papakonstantinou N; Mansouri L; Stavroyianni N; Kanduri C; Stamatopoulos K; Rosenquist R; Kanduri M
Article: LEUKEMIA. 2019;33(10):2416-2428
Inhibition of SYK or BTK augments venetoclax sensitivity in SHP1-negative/BCL-2-positive diffuse large B-cell lymphoma
Sasi BK; Martines C; Xerxa E; Porro F; Kalkan H; Fazio R; Turkalj S; Bojnik E; Pyrzynska B; Stachura J; Zerrouqi A; Bobrowicz M; Winiarska M; Priebe V; Bertoni F; Mansouri L; Rosenquist R; Efremov DG
Article: BLOOD ADVANCES. 2019;3(16):2474-2481
Clinical significance of DNA methylation in chronic lymphocytic leukemia patients: results from 3 UK clinical trials
Wojdacz TK; Amarasinghe HE; Kadalayil L; Beattie A; Forster J; Blakemore SJ; Parker H; Bryant D; Larrayoz M; Clifford R; Robbe P; Davis ZA; Else M; Howard DR; Stamatopoulos B; Steele AJ; Rosenquist R; Collins A; Pettitt AR; Hillmen P; Plass C; Schuh A; Catovsky D; Oscier DG; Rose-Zerilli MJJ; Oakes CC; Strefford JC
Article: BLOOD ADVANCES. 2019;3(12):1891-1896
Inhibition of EZH2 and immune signaling exerts synergistic antitumor effects in chronic lymphocytic leukemia
Chartomatsidou E; Ntoufa S; Kotta K; Rovida A; Akritidou MA; Belloni D; Ferrero E; Trangas T; Stavroyianni N; Anagnostopoulos A; Rosenquist R; Ghia P; Papakonstantinou N; Stamatopoulos K
Article: SCIENCE TRANSLATIONAL MEDICINE. 2019;11(497):eaav5599
Targetable genetic alterations of TCF4 (E2-2) drive immunoglobulin expression in diffuse large B cell lymphoma
Jain N; Hartert K; Tadros S; Fiskus W; Havranek O; Ma MCJ; Bouska A; Heavican T; Kumar D; Deng Q; Moore D; Pak C; Liu CL; Gentles AJ; Hartmann E; Kridel R; Smedby KE; Juliusson G; Rosenquist R; Gascoyne RD; Rosenwald A; Giancotti F; Neelapu SS; Westin J; Vose JM; Lunning MA; Greiner T; Rodig S; Iqbal J; Alizadeh AA; Davis RE; Bhalla K; Green MR
Article: INTERNATIONAL JOURNAL OF CANCER. 2019;144(11):2695-2706
Integrated epigenomic and transcriptomic analysis reveals TP63 as a novel player in clinically aggressive chronic lymphocytic leukemia
Papakonstantinou N; Ntoufa S; Tsagiopoulou M; Moysiadis T; Bhoi S; Malousi A; Psomopoulos F; Mansouri L; Laidou S; Papazoglou D; Gounari M; Pasentsis K; Plevova K; Kuci-Emruli V; Duran-Ferrer M; Davis Z; Ek S; Rossi D; Gaidano G; Ritgen M; Oscier D; Stavroyianni N; Pospisilova S; Davi F; Ghia P; Hadzidimitriou A; Belessi C; Martin-Subero JI; Pott C; Rosenquist R; Stamatopoulos K
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2019;185(4):708-712
Expression of GNAZ, encoding the Gα_z protein, predicts survival in mantle cell lymphoma
Mundt F; Merrien M; Nygren L; Sutton LA; Christensson B; Wahlin BE; Rosenquist R; Sander B; Wasik AM
Article: JOURNAL OF PATHOLOGY. 2019;247(4):416-421
Disease-biased and shared characteristics of the immunoglobulin gene repertoires in marginal zone B cell lymphoproliferations
Xochelli A; Bikos V; Polychronidou E; Galigalidou C; Agathangelidis A; Charlotte F; Moschonas P; Davis Z; Colombo M; Roumelioti M; Sutton L-A; Groenen P; van den Brand M; Boudjoghra M; Algara P; Traverse-Glehen A; Ferrer A; Stalika E; Karypidou M; Kanellis G; Kalpadakis C; Mollejo M; Pangalis G; Vlamos P; Amini R-M; Pospisilova S; Gonzalez D; Ponzoni M; Anagnostopoulos A; Giudicelli V; Lefranc M-P; Espinet B; Panagiotidis P; Piris MA; Du M-Q; Rosenquist R; Papadaki T; Belessi C; Ferrarini M; Oscier D; Tzovaras D; Ghia P; Davi F; Hadzidimitriou A; Stamatopoulos K
Article: BLOOD ADVANCES. 2019;3(3):384-396
Genome-wide promoter methylation of hairy cell leukemia
Arribas AJ; Rinaldi A; Chiodin G; Kwee I; Mensah AA; Cascione L; Rossi D; Kanduri M; Rosenquist R; Zucca E; Johnson PW; Gaidano G; Oakes CC; Bertoni F; Forconi F
Article: HAEMATOLOGICA. 2019;104(2):360-369
Tailored approaches grounded on immunogenetic features for refined prognostication in chronic lymphocytic leukemia
Baliakas P; Moysiadis T; Hadzidimitriou A; Xochelli A; Jeromin S; Agathangelidis A; Mattsson M; Sutton L-A; Minga E; Scarfo L; Rossi D; Davis Z; Villamor N; Parker H; Kotaskova J; Stalika E; Plevova K; Mansouri L; Cortese D; Navarro A; Delgado J; Larrayoz M; Young E; Anagnostopoulos A; Smedby KE; Juliusson G; Sheehy O; Catherwood M; Strefford JC; Stavroyianni N; Belessi C; Pospisilova S; Oscier D; Gaidano G; Campo E; Haferlach C; Ghia P; Rosenquist R; Stamatopoulos K
Article: METHODS IN MOLECULAR BIOLOGY. 2019;1881:51-62
Immunoglobulin Gene Analysis in Chronic Lymphocytic Leukemia.
Agathangelidis A; Rosenquist R; Davi F; Ghia P; Belessi C; Hadzidimitriou A; Stamatopoulos K
Article: BLOOD CANCER JOURNAL. 2018;9(1):1
Genetic correlation between multiple myeloma and chronic lymphocytic leukaemia provides evidence for shared aetiology
Went M; Sud A; Speedy H; Sunter NJ; Foersti A; Law PJ; Johnson DC; Mirabella F; Holroyd A; Li N; Orlando G; Weinhold N; van Duin M; Chen B; Mitchell JS; Mansouri L; Juliusson G; Smedby KE; Jayne S; Majid A; Dearden C; Allsup DJ; Bailey JR; Pratt G; Pepper C; Fegan C; Rosenquist R; Kuiper R; Stephens OW; Bertsch U; Broderick P; Einsele H; Gregory WM; Hillengass J; Hoffmann P; Jackson GH; Joeckel K-H; Nickel J; Noethen MM; da Silva Filho MI; Thomsen H; Walker BA; Broyl A; Davies FE; Hansson M; Goldschmidt H; Dyer MJS; Kaiser M; Sonneveld P; Morgan GJ; Hemminki K; Nilsson B; Catovsky D; Allan JM; Houlston RS
Article: JOURNAL OF VISUALIZED EXPERIMENTS. 2018;(141)
Immunoglobulin Gene Sequence Analysis In Chronic Lymphocytic Leukemia: From Patient Material To Sequence Interpretation
Agathangelidis A; Sutton LA; Hadzidimitriou A; Tresoldi C; Langerak AW; Belessi C; Davi F; Rosenquist R; Stamatopoulos K; Ghia P
Article: BMC BIOINFORMATICS. 2018;19(Suppl 14):414
Automated shape-based clustering of 3D immunoglobulin protein structures in chronic lymphocytic leukemia
Polychronidou E; Kalamaras I; Agathangelidis A; Sutton L-A; Yan X-J; Bikos V; Vardi A; Mochament K; Chiorazzi N; Belessi C; Rosenquist R; Ghia P; Stamatopoulos K; Vlamos P; Chailyan A; Overby N; Marcatili P; Hatzidimitriou A; Tzovaras D
Article: SEMINARS IN CANCER BIOLOGY. 2018;51:1-11
Epigenetic deregulation in chronic lymphocytic leukemia: Clinical and biological impact
Mansouri L; Wierzbinska JA; Plass C; Rosenquist R
Article: ONCOTARGET. 2018;9(40):26019-26031
A novel ex vivo high-throughput assay reveals antiproliferative effects of idelalisib and ibrutinib in chronic lymphocytic leukemia.
Primo D; Scarfò L; Xochelli A; Mattsson M; Ranghetti P; Espinosa AB; Robles A; Gorrochategui J; Martínez-López J; de la Serna J; González M; Gil AC; Anguita E; Iraheta S; Munugalavadla V; Quéva C; Tannheimer S; Rosenquist R; Stamatopoulos K; Ballesteros J; Ghia P
Article: HAEMATOLOGICA. 2018;103(5):865-873
Highly similar genomic landscapes in monoclonal B-cell lymphocytosis and ultra-stable chronic lymphocytic leukemia with low frequency of driver mutations
Agathangelidis A; Ljungstrom V; Scarfo L; Fazi C; Gounari M; Pandzic T; Sutton L-A; Stamatopoulos K; Tonon G; Rosenquist R; Ghia P
Article: BLOOD ADVANCES. 2018;2(6):621-625
Clinical and functional impact of recurrent S1PR1 mutations in mantle cell lymphoma
Wasik AM; Wu C; Mansouri L; Rosenquist R; Pan-Hammarstrom Q; Sander B
Article: ACTA ONCOLOGICA. 2018;57(2):187-194
U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden
Glimelius B; Melin B; Enblad G; Alafuzoff I; Beskow A; Ahlstrom H; Bill-Axelson A; Birgisson H; Bjor O; Edqvist P-H; Hansson T; Helleday T; Hellman P; Henriksson K; Hesselager G; Hultdin M; Haggman M; Hoglund M; Jonsson H; Larsson C; Lindman H; Ljuslinder I; Mindus S; Nygren P; Ponten F; Riklund K; Rosenquist R; Sandin F; Schwenk JM; Stenling R; Stalberg K; Stalberg P; Sundstrom C; Karlsson CT; Westermark B; Bergh A; Claesson-Welsh L; Palmqvist R; Sjoblom T
Article: JOURNAL OF CLINICAL INVESTIGATION. 2018;128(1):427-445
Drug-perturbation-based stratification of blood cancer
Dietrich S; Oles M; Lu J; Sellner L; Anders S; Velten B; Wu B; Huellein J; Liberio MDS; Walther T; Wagner L; Rabe S; Ghidelli-Disse S; Bantscheff M; Oles AK; Slabicki M; Mock A; Oakes CC; Wang S; Oppermann S; Lukas M; Kim V; Sill M; Benner A; Jauch A; Sutton LA; Young E; Rosenquist R; Liu X; Jethwa A; Lee KS; Lewis J; Putzker K; Lutz C; Rossi D; Mokhir A; Oellerich T; Zirlik K; Herling M; Nguyen-Khac F; Plass C; Andersson E; Mustjoki S; von Kalle C; Ho AD; Hensel M; Duerig J; Ringshausen I; Zapatka M; Huber W; Zenz T
Article: CYTOMETRY. PART A : THE JOURNAL OF THE INTERNATIONAL SOCIETY FOR ANALYTICAL CYTOLOGY. 2018;94(1):121-128
Reproducible diagnosis of chronic lymphocytic leukemia by flow cytometry: An European Research Initiative on CLL (ERIC) & European Society for Clinical Cell Analysis (ESCCA) Harmonisation project.
Rawstron AC; Kreuzer K-A; Soosapilla A; Spacek M; Stehlikova O; Gambell P; McIver-Brown N; Villamor N; Psarra K; Arroz M; Milani R; de la Serna J; Cedena MT; Jaksic O; Nomdedeu J; Moreno C; Rigolin GM; Cuneo A; Johansen P; Johnsen HE; Rosenquist R; Niemann CU; Kern W; Westerman D; Trneny M; Mulligan S; Doubek M; Pospisilova S; Hillmen P; Oscier D; Hallek M; Ghia P; Montserrat E
Article: CLINICAL CANCER RESEARCH. 2017;23(17):5292-5301
Chronic Lymphocytic Leukemia with Mutated IGHV4-34 Receptors: Shared and Distinct Immunogenetic Features and Clinical Outcomes
Xochelli A; Baliakas P; Kavakiotis I; Agathangelidis A; Sutton L-A; Minga E; Ntoufa S; Tausch E; Yan X-J; Shanafelt T; Plevova K; Boudjogra M; Rossi D; Davis Z; Navarro A; Sandberg Y; Vojdeman FJ; Scarfo L; Stavroyianni N; Sudarikov A; Veronese S; Tzenou T; Karan-Djurasevic T; Catherwood M; Kienle D; Chatzouli M; Facco M; Bahlo J; Pott C; Pedersen LB; Mansouri L; Smedby KE; Chu CC; Giudicelli V; Lefranc M-P; Panagiotidis P; Juliusson G; Anagnostopoulos A; Vlahavas I; Antic D; Trentin L; Montillo M; Niemann C; Doehner H; Langerak AW; Pospisilova S; Hallek M; Campo E; Chiorazzi N; Maglaveras N; Oscier D; Gaidano G; Jelinek DF; Stilgenbauer S; Chouvarda I; Darzentas N; Belessi C; Davi F; Hadzidimitriou A; Rosenquist R; Ghia P; Stamatopoulos K
Article: LEUKEMIA. 2017;31(7):1547-1554
EGR2 mutations define a new clinically aggressive subgroup of chronic lymphocytic leukemia
Young E; Noerenberg D; Mansouri L; Ljungstrom V; Frick M; Sutton L-A; Blakemore SJ; Galan-Sousa J; Plevova K; Baliakas P; Rossi D; Clifford R; Roos-Weil D; Navrkalova V; Doerken B; Schmitt CA; Smedby KE; Juliusson G; Giacopelli B; Blachly JS; Belessi C; Panagiotidis P; Chiorazzi N; Davi F; Langerak AW; Oscier D; Schuh A; Gaidano G; Ghia P; Xu W; Fan L; Bernard OA; Nguyen-Khac F; Rassenti L; Li J; Kipps TJ; Stamatopoulos K; Pospisilova S; Zenz T; Oakes CC; Strefford JC; Rosenquist R; Damm F
Article: AMERICAN JOURNAL OF PATHOLOGY. 2017;187(7):1454-1458
Numerous Ontogenetic Roads to Mantle Cell Lymphoma Immunogenetic and Immunohistochemical Evidence
Pouliou E; Xochelli A; Kanellis G; Stalika E; Sutton L-A; Navarro A; Agathangelidis A; Dimosthenous K; Anagnostopoulos A; Patsouris E; Korkolopoulou P; Sundstrom C; Ghia P; Ponzoni M; Sander B; Campo E; Rosenquist R; Hadzidimitriou A; Stamatopoulos K; Papadaki T
Article: AMERICAN JOURNAL OF EPIDEMIOLOGY. 2017;185(8):681-687
Possible Interaction Between Cigarette Smoking and HLA-DRB1 Variation in the Risk of Follicular Lymphoma
Baecklund F; Foo J-N; Askling J; Eloranta S; Glimelius I; Liu J; Hjalgrim H; Rosenquist R; Padyukov L; Smedby KE
Article: SCIENTIFIC REPORTS. 2017;7(1):623
Flow Cytometric Measurement of Blood Cells with BCR-ABL1 Fusion Protein in Chronic Myeloid Leukemia
Lof L; Arngarden L; Olsson-Stromberg U; Siart B; Jansson M; Dahlin JS; Thorn I; Christiansson L; Hermansson M; Larsson A; Ahlstrand E; Walinder G; Soderberg O; Rosenquist R; Landegren U; Kamali-Moghaddam M
Article: HAEMATOLOGICA. 2017;102(3):562-572
T cells in chronic lymphocytic leukemia display dysregulated expression of immune checkpoints and activation markers
Palma M; Gentilcore G; Heimersson K; Mozaffari F; Nasman-Glaser B; Young E; Rosenquist R; Hansson L; Osterborg A; Mellstedt H
Article: NATURE COMMUNICATIONS. 2017;8:14175
Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia
Law PJ; Berndt SI; Speedy HE; Camp NJ; Sava GP; Skibola CF; Holroyd A; Joseph V; Sunter NJ; Nieters A; Bea S; Monnereau A; Martin-Garcia D; Goldin LR; Clot G; Teras LR; Quintela I; Birmann BM; Jayne S; Cozen W; Majid A; Smedby KE; Lan Q; Dearden C; Brooks-Wilson AR; Hall AG; Purdue MP; Mainou-Fowler T; Vajdic CM; Jackson GH; Cocco P; Marr H; Zhang Y; Zheng T; Giles GG; Lawrence C; Call TG; Liebow M; Melbye M; Glimelius B; Mansouri L; Glenn M; Curtin K; Diver WR; Link BK; Conde L; Bracci PM; Holly EA; Jackson RD; Tinker LF; Benavente Y; Boffetta P; Brennan P; Maynadie M; McKay J; Albanes D; Weinstein S; Wang Z; Caporaso NE; Morton LM; Severson RK; Riboli E; Vineis P; Vermeulen RCH; Southey MC; Milne RL; Clavel J; Topka S; Spinelli JJ; Kraft P; Ennas MG; Summerfield G; Ferri GM; Harris RJ; Miligi L; Pettitt AR; North KE; Allsup DJ; Fraumeni JFJ; Bailey JR; Offit K; Pratt G; Hjalgrim H; Pepper C; Chanock SJ; Fegan C; Rosenquist R; de Sanjose S; Carracedo A; Dyer MJS; Catovsky D; Campo E; Cerhan JR; Allan JM; Rothman N; Houlston R; Slager SL
Article: CLINICAL CANCER RESEARCH. 2016;22(24):6217-6227
Transposon Mutagenesis Reveals Fludarabine Resistance Mechanisms in Chronic Lymphocytic Leukemia
Pandzic T; Larsson J; He L; Kundu S; Ban K; Akhtar-Ali M; Hellstrom AR; Schuh A; Clifford R; Blakemore SJ; Strefford JC; Baumann T; Lopez-Guillermo A; Campo E; Ljungstrom V; Mansouri L; Rosenquist R; Sjoblom T; Hellstrom M
Article: BLOOD. 2016;128(23):2666-2670
Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma
Mansouri L; Noerenberg D; Young E; Mylonas E; Abdulla M; Frick M; Asmar F; Ljungstroem V; Schneider M; Yoshida K; Skaftason A; Pandzic T; Gonzalez B; Tasidou A; Waldhueter N; Rivas-Delgado A; Angelopoulou M; Ziepert M; Arends CM; Couronne L; Lenze D; Baldus CD; Bastard C; Okosun J; Fitzgibbon J; Doerken B; Drexler HG; Roos-Weil D; Schmitt CA; Munch-Petersen HD; Zenz T; Hansmann M-L; Strefford JC; Enblad G; Bernard OA; Ralfkiaer E; Erlanson M; Korkolopoulou P; Hultdin M; Papadaki T; Gronbaek K; Lopez-Guillermo A; Ogawa S; Kuppers R; Stamatopoulos K; Stavroyianni N; Kanellis G; Rosenwald A; Campo E; Amini R-M; Ott G; Vassilakopoulos TP; Hummel M; Rosenquist R; Damm F
Article: LEUKEMIA. 2016;30(11):2179-2186
Genomic disruption of the histone methyltransferase SETD2 in chronic lymphocytic leukaemia
Parker H; Rose-Zerilli MJJ; Larrayoz M; Clifford R; Edelmann J; Blakemore S; Gibson J; Wang J; Ljungstrom V; Wojdacz TK; Chaplin T; Roghanian A; Davis Z; Parker A; Tausch E; Ntoufa S; Ramos S; Robbe P; Alsolami R; Steele AJ; Packham G; Rodriguez-Vicente AE; Brown L; McNicholl F; Forconi F; Pettitt A; Hillmen P; Dyer M; Cragg MS; Chelala C; Oakes CC; Rosenquist R; Stamatopoulos K; Stilgenbauer S; Knight S; Schuh A; Oscier DG; Strefford JC
Article: NATURE COMMUNICATIONS. 2016;7:13182
Massive and parallel expression profiling using microarrayed single-cell sequencing
Vickovic S; Stahl PL; Salmen F; Giatrellis S; Westholm JO; Mollbrink A; Navarro JF; Custodio J; Bienko M; Sutton L-A; Rosenquist R; Frisen J; Lundeberg J
Article: HAEMATOLOGICA. 2016;101(8):959-967
Different spectra of recurrent gene mutations in subsets of chronic lymphocytic leukemia harboring stereotyped B-cell receptors
Sutton L-A; Young E; Baliakas P; Hadzidimitriou A; Moysiadis T; Plevova K; Rossi D; Kminkova J; Stalika E; Pedersen LB; Malcikova J; Agathangelidis A; Davis Z; Mansouri L; Scarfo L; Boudjoghra M; Navarro A; Muggen AF; Yan X-J; Nguyen-Khac F; Larrayoz M; Panagiotidis P; Chiorazzi N; Niemann CU; Belessi C; Campo E; Strefford JC; Langerak AW; Oscier D; Gaidano G; Pospisilova S; Davi F; Ghia P; Stamatopoulos K; Rosenquist R
Article: ONCOTARGET. 2016;7(25):38180-38190
Genetic heterogeneity in primary and relapsed mantle cell lymphomas: Impact of recurrent CARD11 mutations
Wu C; de Miranda NFCC; Chen L; Wasik AM; Mansouri L; Jurczak W; Galazka K; Dlugosz-Danecka M; Machaczka M; Zhang H; Peng R; Morin RD; Rosenquist R; Sander B; Pan-Hammarstrom Q
Article: ONCOTARGET. 2016;7(24):35946-35959
The histone methyltransferase EZH2 as a novel prosurvival factor in clinically aggressive chronic lymphocytic leukemia
Papakonstantinou N; Ntoufa S; Chartomatsidou E; Kotta K; Agathangelidis A; Giassafaki L; Karamanli T; Bele P; Moysiadis T; Baliakas P; Sutton LA; Stavroyianni N; Anagnostopoulos A; Makris AM; Ghia P; Rosenquist R; Stamatopoulos K
Article: EPIGENETICS. 2016;11(6):449-455
Prognostic impact of epigenetic classification in chronic lymphocytic leukemia: The case of subset #2
Bhoi S; Ljungstrom V; Baliakas P; Mattsson M; Smedby KE; Juliusson G; Rosenquist R; Mansouri L
Article: EPIGENETICS. 2016;11(5):335-343
Epigenetic silencing of miR-26A1 in chronic lymphocytic leukemia and mantle cell lymphoma: Impact on EZH2 expression
Kopparapu PK; Bhoi S; Mansouri L; Arabanian LS; Plevova K; Pospisilova S; Wasik AM; Croci GA; Sander B; Paulli M; Rosenquist R; Kanduri M
Article: CLINICAL CANCER RESEARCH. 2016;22(8):2032-2040
An Immunogenetic Signature of Ongoing Antigen Interactions in Splenic Marginal Zone Lymphoma Expressing IGHV1-2*04 Receptors
Bikos V; Karypidou M; Stalika E; Baliakas P; Xochelli A; Sutton L-A; Papadopoulos G; Agathangelidis A; Papadopoulou E; Davis Z; Algara P; Kanellis G; Traverse-Glehen A; Mollejo M; Anagnostopoulos A; Ponzoni M; Gonzalez D; Pospisilova S; Matutes E; Angel Piris M; Papadaki T; Ghia P; Rosenquist R; Oscier D; Darzentas N; Tzovaras D; Belessi C; Hadzidimitriou A; Stamatopoulos K
Article: BLOOD. 2016;127(8):1007-1016
Whole-exome sequencing in relapsing chronic lymphocytic leukemia: clinical impact of recurrent RPS15 mutations
Ljungstrom V; Cortese D; Young E; Pandzic T; Mansouri L; Plevova K; Ntoufa S; Baliakas P; Clifford R; Sutton L-A; Blakemore SJ; Stavroyianni N; Agathangelidis A; Rossi D; Hoglund M; Kotaskova J; Juliusson G; Belessi C; Chiorazzi N; Panagiotidis P; Langerak AW; Smedby KE; Oscier D; Gaidano G; Schuh A; Davi F; Pott C; Strefford JC; Trentin L; Pospisilova S; Ghia P; Stamatopoulos K; Sjoblom T; Rosenquist R
Article: CLINICAL CANCER RESEARCH. 2016;22(1):167-174
Antigen Selection Shapes the T-cell Repertoire in Chronic Lymphocytic Leukemia
Vardi A; Agathangelidis A; Stalika E; Karypidou M; Siorenta A; Anagnostopoulos A; Rosenquist R; Hadzidimitriou A; Ghia P; Sutton L-A; Stamatopoulos K
Journal article: SCIENCE. 2015;350(6266):1397
The impact of new technologies on clinical decision-making in health care
Rosenquist Brandell R; Kallioniemi O; Wedell A
Article: CLINICAL CANCER RESEARCH. 2015;21(18):4174-4183
Genetics and Prognostication in Splenic Marginal Zone Lymphoma: Revelations from Deep Sequencing
Parry M; Rose-Zerilli MJJ; Ljungstrom V; Gibson J; Wang J; Walewska R; Parker H; Parker A; Davis Z; Gardiner A; McIver-Brown N; Kalpadakis C; Xochelli A; Anagnostopoulos A; Fazi C; de Castro DG; Dearden C; Pratt G; Rosenquist R; Ashton-Key M; Forconi F; Collins A; Ghia P; Matutes E; Pangalis G; Stamatopoulos K; Oscier D; Strefford JC
Article: BLOOD. 2015;126(2):233-241
SF3B1 mutation identifies a distinct subset of myelodysplastic syndrome with ring sideroblasts
Malcovati L; Karimi M; Papaemmanuil E; Ambaglio I; Jadersten M; Jansson M; Elena C; Galli A; Walldin G; Della Porta MG; Raaschou-Jensen K; Travaglino E; Kallenbach K; Pietra D; Ljungstrom V; Conte S; Boveri E; Invernizzi R; Rosenquist R; Campbell PJ; Cazzola M; Lindberg EH
Article: AMERICAN JOURNAL OF PATHOLOGY. 2015;185(6):1740-1748
Molecular Evidence for Antigen Drive in the Natural History of Mantle Cell Lymphoma
Xochelli A; Sutton L-A; Agathangelidis A; Stalika E; Karypidou M; Marantidou F; Navarro Lopez A; Papadopoulos G; Supikova J; Groenen P; Boudjogra M; Sundstrom C; Ponzoni M; Francova HS; Anagnostopoulos A; Pospisilova S; Papadaki T; Tzovaras D; Ghia P; Pott C; Davi F; Campo E; Rosenquist R; Hadzidimitriou A; Belessi C; Stamatopoulos K
Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2015;212(6):833-843
Functional loss of IκBε leads to NF-κB deregulation in aggressive chronic lymphocytic leukemia
Mansouri L; Sutton L-A; Ljungstrom V; Bondza S; Arngarden L; Bhoi S; Larsson J; Cortese D; Kalushkova A; Plevova K; Young E; Gunnarsson R; Falk-Sorqvist E; Lonn P; Muggen AF; Yan X-J; Sander B; Enblad G; Smedby KE; Juliusson G; Belessi C; Rung J; Chiorazzi N; Strefford JC; Langerak AW; Pospisilova S; Davi F; Hellstrom M; Jernberg-Wiklund H; Ghia P; Soderberg O; Stamatopoulos K; Nilsson M; Rosenquist R
Article: BREAST CANCER RESEARCH. 2015;17(1):61
An original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriers
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Article: MOLECULAR MEDICINE. 2015;20(1):720-728
An Entity Evolving into a Community: Defining the Common Ancestor and Evolutionary Trajectory of Chronic Lymphocytic Leukemia Stereotyped Subset #4
Sutton L-A; Papadopoulos G; Hadzidimitriou A; Papadopoulos S; Kostareli E; Rosenquist R; Tzovaras D; Stamatopoulos K
Article: HAEMATOLOGICA. 2015;100(3):370-376
Targeted next-generation sequencing in chronic lymphocytic leukemia: a high-throughput yet tailored approach will facilitate implementation in a clinical setting
Sutton L-A; Ljungstrom V; Mansouri L; Young E; Cortese D; Navrkalova V; Malcikova J; Muggen AF; Trbusek M; Panagiotidis P; Davi F; Belessi C; Langerak AW; Ghia P; Pospisilova S; Stamatopoulos K; Rosenquist R
Article: LEUKEMIA. 2015;29(2):329-336
Recurrent mutations refine prognosis in chronic lymphocytic leukemia
Baliakas P; Hadzidimitriou A; Sutton L-A; Rossi D; Minga E; Villamor N; Larrayoz M; Kminkova J; Agathangelidis A; Davis Z; Tausch E; Stalika E; Kantorova B; Mansouri L; Scarfo L; Cortese D; Navrkalova V; Rose-Zerilli MJJ; Smedby KE; Juliusson G; Anagnostopoulos A; Makris AM; Navarro A; Delgado J; Oscier D; Belessi C; Stilgenbauer S; Ghia P; Pospisilova S; Gaidano G; Campo E; Strefford JC; Stamatopoulos K; Rosenquist R
Article: BLOOD. 2015;125(5):856-859
Not all IGHV3-21 chronic lymphocytic leukemias are equal: prognostic considerations
Baliakas P; Agathangelidis A; Hadzidimitriou A; Sutton L-A; Minga E; Tsanousa A; Scarfo L; Davis Z; Yan X-J; Shanafelt T; Plevova K; Sandberg Y; Vojdeman FJ; Boudjogra M; Tzenou T; Chatzouli M; Chu CC; Veronese S; Gardiner A; Mansouri L; Smedby KE; Pedersen LB; Moreno D; Van Lom K; Giudicelli V; Francova HS; Nguyen-Khac F; Panagiotidis P; Juliusson G; Angelis L; Anagnostopoulos A; Lefranc M-P; Facco M; Trentin L; Catherwood M; Montillo M; Geisler CH; Langerak AW; Pospisilova S; Chiorazzi N; Oscier D; Jelinek DF; Darzentas N; Belessi C; Davi F; Ghia P; Rosenquist R; Stamatopoulos K
Article: IMMUNOGENETICS. 2015;67(1):61-66
Immunoglobulin heavy variable (IGHV) genes and alleles: new entities, new names and implications for research and prognostication in chronic lymphocytic leukaemia
Xochelli A; Agathangelidis A; Kavakiotis I; Minga E; Sutton LA; Baliakas P; Chouvarda I; Giudicelli V; Vlahavas I; Maglaveras N; Bonello L; Trentin L; Tedeschi A; Panagiotidis P; Geisler C; Langerak AW; Pospisilova S; Jelinek DF; Oscier D; Chiorazzi N; Darzentas N; Davi F; Ghia P; Rosenquist R; Hadzidimitriou A; Belessi C; Lefranc M-P; Stamatopoulos K
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2014;167(5):671-680
Impact of ABCB1 single nucleotide polymorphisms 1236C>T and 2677G>T on overall survival in FLT3 wild-type de novo AML patients with normal karyotype
Falk IJ; Fyrberg A; Paul E; Nahi H; Hermanson M; Rosenquist R; Hoglund M; Palmqvist L; Stockelberg D; Wei Y; Green H; Lotfi K
Article: HAEMATOLOGICA. 2014;99(11):1722-1730
Silenced B-cell receptor response to autoantigen in a poor-prognostic subset of chronic lymphocytic leukemia
Bergh A-C; Evaldsson C; Pedersen LB; Geisler C; Stamatopoulos K; Rosenquist R; Rosen A
Article: THE LANCET HAEMATOLOGY. 2014;1(2):e74-e84
Clinical effect of stereotyped B-cell receptor immunoglobulins in chronic lymphocytic leukaemia: a retrospective multicentre study
Baliakas P; Hadzidimitriou A; Sutton L-A; Minga E; Agathangelidis A; Nichelatti M; Tsanousa A; Scarfo L; Davis Z; Yan X-J; Shanafelt T; Plevova K; Sandberg Y; Vojdeman FJ; Boudjogra M; Tzenou T; Chatzouli M; Chu CC; Veronese S; Gardiner A; Mansouri L; Smedby KE; Pedersen LB; van Lom K; Giudicelli V; Francova HS; Nguyen-Khac F; Panagiotidis P; Juliusson G; Angelis L; Anagnostopoulos A; Lefranc M-P; Facco M; Trentin L; Catherwood M; Montillo M; Geisler CH; Langerak AW; Pospisilova S; Chiorazzi N; Oscier D; Jelinek DF; Darzentas N; Belessi C; Davi F; Rosenquist R; Ghia P; Stamatopoulos K
Article: BMC MEDICAL GENETICS. 2014;15:113
A comprehensive evaluation of the role of genetic variation in follicular lymphoma survival
Baecklund F; Foo J-N; Bracci P; Darabi H; Karlsson R; Hjalgrim H; Rosenquist R; Adami H-O; Glimelius B; Melbye M; Conde L; Liu J; Humphreys K; Skibola CF; Smedby KE
Article: HAEMATOLOGICA. 2014;99(8):1285-1291
MDM2 promotor polymorphism and disease characteristics in chronic lymphocytic leukemia: results of an individual patient data-based meta-analysis
Benner A; Mansouri L; Rossi D; Majid A; Willander K; Parker A; Bond G; Pavlova S; Nueckel H; Merkel O; Ghia P; Montserrat E; Kaderi MA; Rosenquist R; Gaidano G; Dyer MJS; Soederkvist P; Linderholm M; Oscier D; Tvaruzkova Z; Pospisilova S; Duehrsen U; Greil R; Doehner H; Stilgenbauer S; Zenz T
Article: EPIGENETICS. 2014;9(6):910-917
microRNA-34b/c on chromosome 11q23 is aberrantly methylated in chronic lymphocytic leukemia
Deneberg S; Kanduri M; Ali D; Bengtzen S; Karimi M; Qu Y; Kimby E; Mansouri L; Rosenquist R; Lennartsson A; Lehmann S
Article: LEUKEMIA RESEARCH. 2014;38(6):682-690
Identification of B-cell lymphoma subsets by plasma protein profiling using recombinant antibody microarrays
Pauly F; Smedby KE; Jerkeman M; Hjalgrim H; Ohlsson M; Rosenquist R; Borrebaeck CAK; Wingren C
Article: CLINICAL CANCER RESEARCH. 2014;20(2):323-330
IgG-Switched CLL Has a Distinct Immunogenetic Signature from the Common MD Variant: Ontogenetic Implications
Vardi A; Agathangelidis A; Sutton L-A; Chatzouli M; Scarfo L; Mansouri L; Douka V; Anagnostopoulos A; Darzentas N; Rosenquist R; Ghia P; Belessi C; Stamatopoulos K
Article: NATURE GENETICS. 2014;46(1):56-60
A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia
Speedy HE; Di Bernardo MC; Sava GP; Dyer MJS; Holroyd A; Wang Y; Sunter NJ; Mansouri L; Juliusson G; Smedby KE; Roos G; Jayne S; Majid A; Dearden C; Hall AG; Mainou-Fowler T; Jackson GH; Summerfield G; Harris RJ; Pettitt AR; Allsup DJ; Bailey JR; Pratt G; Pepper C; Fegan C; Rosenquist R; Catovsky D; Allan JM; Houlston RS
Article: AMERICAN JOURNAL OF HEMATOLOGY. 2013;88(12):1001-1006
Decreased survival in normal karyotype AML with single-nucleotide polymorphisms in genes encoding the AraC metabolizing enzymes cytidine deaminase and 5′-nucleotidase
Falk IJ; Fyrberg A; Paul E; Nahi H; Hermanson M; Rosenquist R; Hoglund M; Palmqvist L; Stockelberg D; Wei Y; Green H; Lotfi K
Article: EPIGENETICS. 2013;8(12):1280-1288
A key role for EZH2 in epigenetic silencing of HOX genes in mantle cell lymphoma
Kanduri M; Sander B; Ntoufa S; Papakonstantinou N; Sutton L; Stamatopoulos K; Kanduri C; Rosenquist R
Article: LEUKEMIA. 2013;27(11):2196-2199
Distinct patterns of novel gene mutations in poor-prognostic stereotyped subsets of chronic lymphocytic leukemia: the case of SF3B1 and subset #2
Strefford JC; Sutton L-A; Baliakas P; Agathangelidis A; Malcikova J; Plevova K; Scarfo L; Davis Z; Stalika E; Cortese D; Cahill N; Pedersen LB; di Celle PF; Tzenou T; Geisler C; Panagiotidis P; Langerak AW; Chiorazzi N; Pospisilova S; Oscier D; Davi F; Belessi C; Mansouri L; Ghia P; Stamatopoulos K; Rosenquist R
Article: BLOOD. 2013;122(15):2673-2682
Two main genetic pathways lead to the transformation of chronic lymphocytic leukemia to Richter syndrome
Chigrinova E; Rinaldi A; Kwee I; Rossi D; Rancoita PMV; Strefford JC; Oscier D; Stamatopoulos K; Papadaki T; Berger F; Young KH; Murray F; Rosenquist R; Greiner TC; Chan WC; Orlandi EM; Lucioni M; Marasca R; Inghirami G; Ladetto M; Forconi F; Cogliatti S; Votavova H; Swerdlow SH; Stilgenbauer S; Piris MA; Matolcsy A; Spagnolo D; Nikitin E; Zamo A; Gattei V; Bhagat G; Ott G; Zucca E; Gaidano G; Bertoni F
Article: MOLECULAR MEDICINE. 2013;19(1):230-236
Temporal Dynamics of Clonal Evolution in Chronic Lymphocytic Leukemia with Stereotyped IGHV4-34/IGKV2-30 Antigen Receptors: Longitudinal Immunogenetic Evidence
Sutton L-A; Kostareli E; Stalika E; Tsaftaris A; Anagnostopoulos A; Darzentas N; Rosenquist R; Stamatopoulos K
Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2013;210(9):1729-1742
DNA repair genes are selectively mutated in diffuse large B cell lymphomas
de Miranda NFCC; Peng R; Georgiou K; Wu C; Sorqvist EF; Berglund M; Chen L; Gao Z; Lagerstedt K; Lisboa S; Roos F; van Wezel T; Teixeira MR; Rosenquist R; Sundstrom C; Enblad G; Nilsson M; Zeng Y; Kipling D; Pan-Hammarstrom Q
Article: AMERICAN JOURNAL OF HEMATOLOGY. 2013;88(8):647-651
Short telomere length is associated with NOTCH1/SF3B1/TP53 aberrations and poor outcome in newly diagnosed chronic lymphocytic leukemia patients
Mansouri L; Grabowski P; Degerman S; Svenson U; Gunnarsson R; Cahill N; Smedby KE; Geisler C; Juliusson G; Roos G; Rosenquist R
Article: LEUKEMIA AND LYMPHOMA. 2013;54(8):1769-1779
Molecular characterization of neoplastic and normal "sister" lymphoblastoid B-cell lines from chronic lymphocytic leukemia
Myhrinder AL; Hellqvist E; Bergh A-C; Jansson M; Nilsson K; Hultman P; Jonasson J; Buhl AM; Pedersen LB; Jurlander J; Klein E; Weit N; Herling M; Rosenquist R; Rosen A
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2013;162(2):221-228
rs2072135, a low-penetrance variant for chronic lymphocytic leukaemia?
Sava GP; Speedy HE; Di Bernardo MC; Deaglio S; Karabon L; Frydecka I; Woszczyk D; Rossi D; Gaidano G; Mansouri L; Smedby KE; Juliusson G; Rosenquist R; Catovsky D; Houlston RS
Article: EPIGENETICS. 2013;8(7):720-729
ANGPT2 promoter methylation is strongly associated with gene expression and prognosis in chronic lymphocytic leukemia
Martinelli S; Kanduri M; Maffei R; Fiorcari S; Bulgarelli J; Marasca R; Rosenquist R
Article: PLOS GENETICS. 2013;9(3):e1003212
Genome-Wide Association Study in BRCA1 Mutation Carriers Identifies Novel Loci Associated with Breast and Ovarian Cancer Risk
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Article: LEUKEMIA. 2013;27(1):150-158
450K-array analysis of chronic lymphocytic leukemia cells reveals global DNA methylation to be relatively stable over time and similar in resting and proliferative compartments
Cahill N; Bergh A-C; Kanduri M; Goransson-Kultima H; Mansouri L; Isaksson A; Ryan F; Smedby KE; Juliusson G; Sundstrom C; Rosen A; Rosenquist R
Article: EPIGENETICS. 2012;7(12):1435-1442
Distinct transcriptional control in major immunogenetic subsets of chronic lymphocytic leukemia exhibiting subset-biased global DNA methylation profiles
Kanduri M; Marincevic M; Halldorsdottir AM; Mansouri L; Junevik K; Ntoufa S; Kultima HG; Isaksson A; Juliusson G; Andersson P-O; Ehrencrona H; Stamatopoulos K; Rosenquist R
Article: JOURNAL OF GENETIC COUNSELING. 2012;21(4):510-526
What Information Do Cancer Genetic Counselees Prioritize?
Roshanai AH; Lampic C; Ingvoldstad C; Askmalm MS; Bjorvatn C; Rosenquist R; Nordin K
Article: ANTICANCER RESEARCH. 2012;32(8):3125-3136
Screening for Cytotoxic Compounds in Poor-prognostic Chronic Lymphocytic Leukemia
Norberg M; Lindhagen E; Kanduri M; Rickardson L; Sundstrom C; Stamatopoulos K; Rosenquist R; Aleskog A
Article: AMERICAN JOURNAL OF HEMATOLOGY. 2012;87(7):737-740
Next generation RNA-sequencing in prognostic subsets of chronic lymphocytic leukemia
Mansouri L; Gunnarsson R; Sutton L-A; Ameur A; Hooper SD; Mayrhofer M; Juliusson G; Isaksson A; Gyllensten U; Rosenquist R
Article: BRITISH JOURNAL OF CANCER. 2012;106(12):2016-2024
Association of PHB 1630 C>T and MTHFR 677 C>T polymorphisms with breast and ovarian cancer risk in BRCA1/2 mutation carriers: results from a multicenter study
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Article: CLINICAL LYMPHOMA, MYELOMA AND LEUKEMIA. 2012;12(3):201-206
IGHV3-21 Gene Frequency in a Swedish Cohort of Patients With Newly Diagnosed Chronic Lymphocytic Leukemia
Cahill N; Sutton L-A; Jansson M; Murray F; Mansouri L; Gunnarsson R; Ryan F; Smedby KE; Geisler C; Juliusson G; Rosenquist R
Article: BLOOD. 2012;119(19):4467-4475
Stereotyped B-cell receptors in one-third of chronic lymphocytic leukemia: a molecular classification with implications for targeted therapies
Agathangelidis A; Darzentas N; Hadzidimitriou A; Brochet X; Murray F; Yan X-J; Davis Z; van Gastel-Mol EJ; Tresoldi C; Chu CC; Cahill N; Giudicelli V; Tichy B; Pedersen LB; Foroni L; Bonello L; Janus A; Smedby K; Anagnostopoulos A; Merle-Beral H; Laoutaris N; Juliusson G; di Celle PF; Pospisilova S; Jurlander J; Geisler C; Tsaftaris A; Lefranc M-P; Langerak AW; Oscier DG; Chiorazzi N; Belessi C; Davi F; Rosenquist R; Ghia P; Stamatopoulos K
Article: PHARMACOGENOMICS JOURNAL. 2012;12(2):111-118
Association of ABCB1 polymorphisms with survival and in vitro cytotoxicty in de novo acute myeloid leukemia with normal karyotype
Green H; Falk IJ; Lotfi K; Paul E; Hermansson M; Rosenquist R; Paul C; Nahi H
Article: AMERICAN JOURNAL OF HEMATOLOGY. 2012;87(4):361-367
Mantle cell lymphoma displays a homogenous methylation profile: A comparative analysis with chronic lymphocytic leukemia
Halldorsdottir AM; Kanduri M; Marincevic M; Mansouri L; Isaksson A; Goransson H; Axelsson T; Agarwal P; Jernberg-Wiklund H; Stamatopoulos K; Sander B; Ehrencrona H; Rosenquist R
Article: BREAST CANCER RESEARCH. 2012;14(1):R33
Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers
Antoniou AC; Kuchenbaecker KB; Soucy P; Beesley J; Chen X; McGuffog L; Lee A; Barrowdale D; Healey S; Sinilnikova OM; Caligo MA; Loman N; Harbst K; Lindblom A; Arver B; Rosenquist R; Karlsson P; Nathanson K; Domchek S; Rebbeck T; Jakubowska A; Lubinski J; Jaworska K; Durda K; Zlowowcka-Perlowska E; Osorio A; Duran M; Andres R; Benitez J; Hamann U; Hogervorst FB; van Os TA; Verhoef S; Meijers-Heijboer HEJ; Wijnen J; Garcia EBG; Ligtenberg MJ; Kriege M; Collee M; Ausems MGEM; Oosterwijk JC; Peock S; Frost D; Ellis SD; Platte R; Fineberg E; Evans DG; Lalloo F; Jacobs C; Eeles R; Adlard J; Davidson R; Cole T; Cook J; Paterson J; Douglas F; Brewer C; Hodgson S; Morrison PJ; Walker L; Rogers MT; Donaldson A; Dorkins H; Godwin AK; Bove B; Stoppa-Lyonnet D; Houdayer C; Buecher B; de Pauw A; Mazoyer S; Calender A; Leone M; Bressac-de Paillerets B; Caron O; Sobol H; Frenay M; Prieur F; Ferrer SF; Mortemousque I; Buys S; Daly M; Miron A; Terry MB; Hopper JL; John EM; Southey M; Goldgar D; Singer CF; Fink-Retter A; Tea M-K; Kaulich DG; Hansen TVO; Nielsen FC; Barkardottir RB; Gaudet M; Kirchhoff T; Joseph V; Dutra-Clarke A; Offit K; Piedmonte M; Kirk J; Cohn D; Hurteau J; Byron J; Fiorica J; Toland AE; Montagna M; Oliani C; Imyanitov E; Isaacs C; Tihomirova L; Blanco I; Lazaro C; Teule A; Del Valle J; Gayther SA; Odunsi K; Gross J; Karlan BY; Olah E; Teo S-H; Ganz PA; Beattie MS; Dorfling CM; van Rensburg EJ; Diez O; Kwong A; Schmutzler RK; Wappenschmidt B; Engel C; Meindl A; Ditsch N; Arnold N; Heidemann S; Niederacher D; Preisler-Adams S; Gadzicki D; Varon-Mateeva R; Deissler H; Gehrig A; Sutter C; Kast K; Fiebig B; Schaefer D; Caldes T; de la Hoya M; Nevanlinna H; Muranen TA; Lesperance B; Spurdle AB; Neuhausen SL; Ding YC; Wang X; Fredericksen Z; Pankratz VS; Lindor NM; Peterlongo P; Manoukian S; Peissel B; Zaffaroni D; Bonanni B; Bernard L; Dolcetti R; Papi L; Ottini L; Radice P; Greene MH; Loud JT; Andrulis IL; Ozcelik H; Mulligan AM; Glendon G; Thomassen M; Gerdes A-M; Jensen UB; Skytte A-B; Kruse TA; Chenevix-Trench G; Couch FJ; Simard J; Easton DF
Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2012;209(2):291-305
Cernunnos influences human immunoglobulin class switch recombination and may be associated with B cell lymphomagenesis
Du L; Peng R; Bjorkman A; de Miranda NF; Rosner C; Kotnis A; Berglund M; Liu C; Rosenquist R; Enblad G; Sundstrom C; Hojjat-Farsangi M; Rabbani H; Teixeira MR; Revy P; Durandy A; Zeng Y; Gennery AR; de Villartay J-P; Pan-Hammarstrom Q
Article: ONCOIMMUNOLOGY. 2012;1(1):18-27
Lymphoblastoid cell line with B1 cell characteristics established from a chronic lymphocytic leukemia clone by in vitro EBV infection
Rosen A; Bergh A-C; Gogolak P; Evaldsson C; Myhrinder AL; Hellqvist E; Rasul A; Bjorkholm M; Jansson M; Mansouri L; Liu A; Teh BT; Rosenquist R; Klein E
Article: BLOOD. 2011;118(22):5905-5913
Presence of FLT3-ITD and high BAALC expression are independent prognostic markers in childhood acute myeloid leukemia
Staffas A; Kanduri M; Hovland R; Rosenquist R; Ommen HB; Abrahamsson J; Forestier E; Jahnukainen K; Jonsson OG; Zeller B; Palle J; Lonnerholm G; Hasle H; Palmqvist L; Ehrencrona H
Article: BLOOD. 2011;118(11):3088-3095
Is there a role for antigen selection in mantle cell lymphoma? Immunogenetic support from a series of 807 cases
Hadzidimitriou A; Agathangelidis A; Darzentas N; Murray F; Delfau-Larue M-H; Pedersen LB; Navarro Lopez A; Dagklis A; Rombout P; Beldjord K; Kolstad A; Dreyling MH; Anagnostopoulos A; Tsaftaris A; Mavragani-Tsipidou P; Rosenwald A; Ponzoni M; Groenen P; Ghia P; Sander B; Papadaki T; Campo E; Geisler C; Rosenquist R; Davi F; Pott C; Stamatopoulos K
Article: HAEMATOLOGICA. 2011;96(8):1161-1169
Array-based genomic screening at diagnosis and during follow-up in chronic lymphocytic leukemia
Gunnarsson R; Mansouri L; Isaksson A; Goransson H; Cahill N; Jansson M; Rasmussen M; Lundin J; Norin S; Buhl AM; Smedby KE; Hjalgrim H; Karlsson K; Jurlander J; Geisler C; Juliusson G; Rosenquist R
Article: HAEMATOLOGICA. 2011;96(8):1153-1160
LPL is the strongest prognostic factor in a comparative analysis of RNA-based markers in early chronic lymphocytic leukemia
Kaderi MA; Kanduri M; Buhl AM; Sevov M; Cahill N; Gunnarsson R; Jansson M; Smedby KE; Hjalgrim H; Jurlander J; Juliusson G; Mansouri L; Rosenquist R
Article: LEUKEMIA. 2011;25(6):979-984
Immunoglobulin sequence analysis and prognostication in CLL: guidelines from the ERIC review board for reliable interpretation of problematic cases
Langerak AW; Davi F; Ghia P; Hadzidimitriou A; Murray F; Potter KN; Rosenquist R; Stamatopoulos K; Belessi C
Article: LEUKEMIA RESEARCH. 2011;35(4):438-443
Quantitative evaluation of p16^INK4a promoter methylation using pyrosequencing in de novo diffuse large B-cell lymphoma
Zainuddin N; Kanduri M; Berglund M; Lindell M; Amini R-M; Roos G; Sundstrom C; Enblad G; Rosenquist R
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2011;152(6):743-753
Minimal residual disease assessment in childhood acute lymphoblastic leukaemia: a Swedish multi-centre study comparing real-time polymerase chain reaction and multicolour flow cytometry
Thorn I; Forestier E; Botling J; Thuresson B; Wasslavik C; Bjorklund E; Li A; Lindstrom-Eriksson E; Malec M; Gronlund E; Torikka K; Heldrup J; Abrahamsson J; Behrendtz M; Soderhall S; Jacobsson S; Olofsson T; Porwit A; Lonnerholm G; Rosenquist R; Sundstrom C
Article: BLOOD CANCER JOURNAL. 2011;1(3):e12
The novel NF-κB inhibitor IMD-0354 induces apoptosis in chronic lymphocytic leukemia
Kanduri M; Tobin G; Aleskog A; Nilsson K; Rosenquist R
Article: LEUKEMIA RESEARCH. 2011;35(2):272-274
TP53 Mutations are infrequent in newly diagnosed chronic lymphocytic leukemia
Zainuddin N; Murray F; Kanduri M; Gunnarsson R; Smedby KE; Enblad G; Jurlander J; Juliusson G; Rosenquist R
Article: GENES CHROMOSOMES AND CANCER. 2011;50(2):113-121
High-Resolution Genomic Screening in Mantle Cell Lymphoma-Specific Changes Correlate with Genomic Complexity, the Proliferation Signature and Survival
Halldorsdottir AM; Sander B; Goransson H; Isaksson A; Kimby E; Mansouri M; Rosenquist R; Ehrencrona H
Article: HAEMATOLOGICA. 2010;95(12):2072-2079
Distinct gene expression profiles in subsets of chronic lymphocytic leukemia expressing stereotyped IGHV4-34 B-cell receptors
Marincevic M; Mansouri M; Kanduri M; Isaksson A; Goransson H; Smedby KE; Jurlander J; Juliusson G; Davi F; Stamatopoulos K; Rosenquist R
Article: FAMILIAL CANCER. 2010;9(4):669-679
Disclosing cancer genetic information within families: perspectives of counselees and their at-risk relatives
Roshanai AH; Lampic C; Rosenquist R; Nordin K
Article: HAEMATOLOGICA. 2010;95(9):1519-1525
High-density screening reveals a different spectrum of genomic aberrations in chronic lymphocytic leukemia patients with 'stereotyped' IGHV3-21 and IGHV4-34 B-cell receptors
Marincevic M; Cahill N; Gunnarsson R; Isaksson A; Mansouri M; Goransson H; Rasmussen M; Jansson M; Ryan F; Karlsson K; Adami H-O; Davi F; Jurlander J; Juliusson G; Stamatopoulos K; Rosenquist R
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2010;150(4):473-479
Verification that common variation at 2q37.1, 6p25.3, 11q24.1, 15q23, and 19q13.32 influences chronic lymphocytic leukaemia risk
Crowther-Swanepoel D; Mansouri M; Enjuanes A; Vega A; Smedby KE; Ruiz-Ponte C; Jurlander J; Juliusson G; Montserrat E; Catovsky D; Campo E; Carracedo A; Rosenquist R; Houlston RS
Article: LEUKEMIA. 2010;24(7):1317-1324
Intraclonal diversification of immunoglobulin light chains in a subset of chronic lymphocytic leukemia alludes to antigen-driven clonal evolution
Kostareli E; Sutton L-A; Hadzidimitriou A; Darzentas N; Kouvatsi A; Tsaftaris A; Anagnostopoulos A; Rosenquist R; Stamatopoulos K
Article: AMERICAN JOURNAL OF HEMATOLOGY. 2010;85(6):418-425
Identification of uniquely expressed transcription factors in highly purified B-cell lymphoma samples
Andreasson U; Eden P; Peterson C; Hogerkorp C-M; Jerkeman M; Andersen N; Berglund M; Sundstrom C; Rosenquist R; Borrebaeck CAK; Ek S
Article: LEUKEMIA. 2010;24(5):924-931
Relapsed childhood high hyperdiploid acute lymphoblastic leukemia: presence of preleukemic ancestral clones and the secondary nature of microdeletions and RTK-RAS mutations
Davidsson J; Paulsson K; Lindgren D; Lilljebjorn H; Chaplin T; Forestier E; Andersen MK; Nordgren A; Rosenquist R; Fioretos T; Young BD; Johansson B
Article: ANNALS OF THE RHEUMATIC DISEASES. 2010;69(4):654-659
Rheumatoid arthritis, treatment with corticosteroids and risk of malignant lymphomas: results from a case-control study
Hellgren K; Iliadou A; Rosenquist R; Feltelius N; Backlin C; Enblad G; Askling J; Baecklund E
Article: LEUKEMIA RESEARCH. 2010;34(3):301-306
Lipoprotein lipase is differentially expressed in prognostic subsets of chronic lymphocytic leukemia but displays invariably low catalytical activity
Mansouri M; Sevov M; Fahlgren E; Tobin G; Jondal M; Osorio L; Roos G; Olivecrona G; Rosenquist R
Article: LEUKEMIA RESEARCH. 2010;34(3):335-339
Lack of association between the MDM2 promoter polymorphism SNP309 and clinical outcome in chronic lymphocytic leukemia
Kaderi MA; Mansouri M; Zainuddin N; Cahill N; Gunnarsson R; Jansson M; Kimby E; Aleskog A; Lundin J; Glimelius B; Melbye M; Juliusson G; Jurlander J; Rosenquist R
Article: NATURE GENETICS. 2010;42(2):132-136
Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk
Crowther-Swanepoel D; Broderick P; Di Bernardo MC; Dobbins SE; Torres M; Mansouri M; Ruiz-Ponte C; Enjuanes A; Rosenquist R; Carracedo A; Jurlander J; Campo E; Juliusson G; Montserrat E; Smedby KE; Dyer MJS; Matutes E; Dearden C; Sunter NJ; Hall AG; Mainou-Fowler T; Jackson GH; Summerfield G; Harris RJ; Pettitt AR; Allsup DJ; Bailey JR; Pratt G; Pepper C; Fegan C; Parker A; Oscier D; Allan JM; Catovsky D; Houlston RS
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2010;84(2):117-127
Applicability of IG/TCR gene rearrangements as targets for minimal residual disease assessment in a population-based cohort of Swedish childhood acute lymphoblastic leukaemia diagnosed 2002-2006
Thorn I; Forestier E; Thuresson B; Wasslavik C; Malec M; Li A; Lindstrom-Eriksson E; Botling J; Barbany G; Jacobsson S; Olofsson T; Porwit A; Sundstrom C; Rosenquist R
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2010;84(2):109-116
IGHV3-21 gene usage is associated with high TCL1 expression in chronic lymphocytic leukemia
Mansouri MR; Sevov M; Aleskog A; Jondal M; Merup M; Sundstrom C; Osorio L; Rosenquist R
Article: BLOOD. 2010;115(2):296-305
Differential genome-wide array-based methylation profiles in prognostic subsets of chronic lymphocytic leukemia
Kanduri M; Cahill N; Goransson H; Enstrom C; Ryan F; Isaksson A; Rosenquist R
Article: LEUKEMIA. 2010;24(1):125-132
A different ontogenesis for chronic lymphocytic leukemia cases carrying stereotyped antigen receptors: molecular and computational evidence
Darzentas N; Hadzidimitriou A; Murray F; Hatzi K; Josefsson P; Laoutaris N; Moreno C; Anagnostopoulos A; Jurlander J; Tsaftaris A; Chiorazzi N; Belessi C; Ghia P; Rosenquist R; Davi F; Stamatopoulos K
Article: AMERICAN JOURNAL OF HEMATOLOGY. 2009;84(12):803-808
Identification of molecular targets associated with transformed diffuse large B cell lymphoma using highly purified tumor cells
Andreasson U; Dictor M; Jerkeman M; Berglund M; Sundstrom C; Linderoth J; Rosenquist R; Borrebaeck CAK; Ek S
Article: BLOOD. 2009;114(20):4460-4468
Extensive intraclonal diversification in a subgroup of chronic lymphocytic leukemia patients with stereotyped IGHV4-34 receptors: implications for ongoing interactions with antigen
Sutton L-A; Kostareli E; Hadzidimitriou A; Darzentas N; Tsaftaris A; Anagnostopoulos A; Rosenquist R; Stamatopoulos K
Article: LEUKEMIA AND LYMPHOMA. 2009;50(9):1528-1534
Genome-wide microarray-based comparative genomic hybridization analysis of lymphoplasmacytic lymphomas reveals heterogeneous aberrations
Buckley PG; Walsh SH; Laurell A; Sundstrom C; Roos G; Langford CF; Dumanski JP; Rosenquist R
Article: LEUKEMIA AND LYMPHOMA. 2009;50(9):1512-1518
Low p14ARF expression in de novo acute myeloid leukemia with normal karyotype is associated with poor survival
Paul E; Uggla B; Deneberg S; Bengtzen S; Hermansson M; Dahlman I; Rosenquist R; Wiman KG; Nahi H
Article: LEUKEMIA RESEARCH. 2009;33(8):1047-1054
Monitoring minimal residual disease with flow cytometry, antigen-receptor gene rearrangements and fusion transcript quantification in Philadelphia-positive childhood acute lymphoblastic leukemia
Thorn I; Botling J; Hermansson M; Lonnerholm G; Sundstrom C; Rosenquist R; Barbany G
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2009;83(1):22-34
In vitro activity of 20 agents in different prognostic subgroups of chronic lymphocytic leukemia - rolipram and prednisolone active in cells from patients with poor prognosis
Lindhagen E; Norberg M; Kanduri M; Tobin G; Saisanen L; Aberg M; Gustafsson MG; Sundstrom C; Rosenquist R; Aleskog A
Article: PLOS ONE. 2009;4(6):e6057
Quantification of Normal Cell Fraction and Copy Number Neutral LOH in Clinical Lung Cancer Samples Using SNP Array Data
Goransson H; Edlund K; Rydaker M; Rasmussen M; Winquist J; Ekman S; Bergqvist M; Thomas A; Lambe M; Rosenquist R; Holmberg L; Micke P; Botling J; Isaksson A
Article: JOURNAL OF GENETIC COUNSELING. 2009;18(2):185-194
Cancer Genetic Counselees' Self-Reported Psychological Distress, Changes in Life, and Adherence to Recommended Surveillance Programs 3-7 Years Post Counseling
Roshanai AH; Rosenquist R; Lampic C; Nordin K
Article: MUTATION RESEARCH - FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS. 2009;660(1-2):1-11
Analysis of a set of missense, frameshift, and in-frame deletion variants of BRCA1
Carvalho M; Pino MA; Karchin R; Beddor J; Godinho-Netto M; Mesquita RD; Rodarte RS; Vaz DC; Monteiro VA; Manoukian S; Colombo M; Ripamonti CB; Rosenquist R; Suthers G; Borg A; Radice P; Grist SA; Monteiro ANA; Billack B
Article: BLOOD. 2009;113(2):403-411
Evidence for the significant role of immunoglobulin light chains in antigen recognition and selection in chronic lymphocytic leukemia
Hadzidimitriou A; Darzentas N; Murray F; Smilevska T; Arvaniti E; Tresoldi C; Tsaftaris A; Laoutaris N; Anagnostopoulos A; Davi F; Ghia P; Rosenquist R; Stamatopoulos K; Belessi C
Article: LEUKEMIA RESEARCH. 2009;33(1):60-66
TP53 mutations predict for poor survival in de novo diffuse large B-cell lymphoma of germinal center subtype
Zainuddin N; Berglund M; Wanders A; Ren Z-P; Amini R-M; Lindell M; Kanduri M; Roos G; Rosenquist R; Enblad G
Article: ACTA ONCOLOGICA. 2009;48(7):999-1009
Does enhanced information at cancer genetic counseling improve counselees' knowledge, risk perception, satisfaction and negotiation of information to at-risk relatives? - a randomized study
Roshanai AH; Rosenquist R; Lampic C; Nordin K
Article: LEUKEMIA AND LYMPHOMA. 2008;49(12):2333-2343
Rapamycin shows anticancer activity in primary chronic lymphocytic leukemia cells in vitro, as single agent and in drug combination
Aleskog A; Norberg M; Nygren P; Rickardson L; Kanduri M; Tobin G; Aberg M; Gustafsson MG; Rosenquist R; Lindhagen E
Article: BMC BIOINFORMATICS. 2008;9:409
Normalization of Illumina Infinium whole-genome SNP data improves copy number estimates and allelic intensity ratios
Staaf J; Vallon-Christersson J; Lindgren D; Juliusson G; Rosenquist R; Hoglund M; Borg A; Ringner M
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2008;81(3):218-225
U-2973, a novel B-cell line established from a patient with a mature B-cell leukemia displaying concurrent t(14;18) and MYC translocation to a non-IG gene partner
Bostrom H; Leuchowius K-J; Hallbook H; Nordgren A; Thorn I; Thorselius M; Rosenquist R; Soderberg O; Sundstrom C
Article: GENES CHROMOSOMES AND CANCER. 2008;47(8):697-711
Screening for copy-number alterations and loss of heterozygosity in chronic lymphocytic leukemia -: A comparative study of four differently designed, high resolution Microarray platforms
Gunnarsson R; Staaf J; Jansson M; Ottesen AM; Goransson H; Liljedahl U; Ralfkiaer U; Mansouri M; Buhl AM; Smedby KE; Hialgrim H; Syvanen A-C; Borg A; Isaksson A; Jurlander J; Juliusson G; Rosenquist R
Article: CANCER LETTERS. 2008;265(1):98-106
Phenotypic protein profiling of different B cell sub-populations using antibody CD-microarrays
Ellmark P; Hogerkorp CM; Ek S; Belov L; Berglund M; Rosenquist R; Christopherson RI; Borrebaeck CAK
Article: BLOOD. 2008;111(7):3838-3848
A new perspective:: molecular motifs on oxidized LDL, apoptotic cells, and bacteria are targets for chronic lymphocytic leukemia antibodies
Myhrinder AL; Hellqvist E; Sidorova E; Soederberg A; Baxendale H; Dahle C; Willander K; Tobin G; Baeckman E; Soederberg O; Rosenquist R; Hoerkkoe S; Rosen A
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2008;141(1):69-72
Expression of the human germinal-centre-associated lymphoma protein in diffuse large B-cell lymphomas in patients with rheumatoid arthritis
Baecklund E; Natkunam Y; Backlin C; Iliadou A; Askling J; Ekbom A; Feltelius N; Klareskog L; Enblad G; Lossos IS; Levy R; Sundstroem C; Rosenquist R
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2008;140(6):665-672
Outcome of ETV6/RUNX1-positive childhood acute lymphoblastic leukaemia in the NOPHO-ALL-1992 protocol:: frequent late relapses but good overall survival
Forestier E; Heyman M; Andersen MK; Autio K; Blennow E; Borgstrom G; Golovleva I; Heim S; Heinonen K; Hovland R; Johannsson JH; Kerndrup G; Nordgren A; Rosenquist R; Swolin B; Johansson B
Article: LEUKEMIA AND LYMPHOMA. 2008;49(3):477-487
Characterization of 6q deletions in mature B cell lymphomas and childhood acute lymphoblastic leukemia
Thelander EF; Ichimura K; Corcoran M; Barbany G; Nordgren A; Heyman M; Berglund M; Mungall A; Rosenquist R; Collins VP; Grander D; Larsson C; Lagercrantz S
Article: BLOOD. 2008;111(4):2246-2252
Short telomeres are associated with genetic complexity, high-risk genomic aberrations, and short survival in chronic lymphocytic leukemia
Roos G; Kroeber A; Grabowski P; Kienle D; Buehler A; Doehner H; Rosenquist R; Stilgenbauer S
Article: CANCER LETTERS. 2008;259(2):138-145
B cell lymphomas express CX₃CR1 a non-B cell lineage adhesion molecule
Andreasson U; Ek S; Merz H; Rosenquist R; Andersen N; Jerkeman M; Dictor M; Borrebaeck CAK
Article: LEUKEMIA. 2008;22(2):339-343
The BCL-2 promoter (-938C>A) polymorphism does not predict clinical outcome in chronic lymphocytic leukemia
Kaderi MA; Norberg M; Murray F; Merup M; Sundstrom C; Roos G; Aleskog A; Karlsson K; Axelsson T; Tobin G; Rosenquist R
Article: BLOOD. 2008;111(3):1524-1533
Stereotyped patterns of somatic hypermutation in subsets of patients with chronic lymphocytic leukemia: implications for the role of antigen selection in leukemogenesis
Murray F; Darzentas N; Hadzidimitriou A; Tobin G; Boudjogra M; Scielzo C; Laoutaris N; Karlsson K; Baran-Marzsak F; Tsaftaris A; Moreno C; Anagnostopoulos A; Caligaris-Cappio F; Vaur D; Ouzounis C; Belessi C; Ghia P; Davi F; Rosenquist R; Stamatopoulos K
Article: GENOME BIOLOGY. 2008;9(9):R136
Segmentation-based detection of allelic imbalance and loss-of-heterozygosity in cancer cells using whole genome SNP arrays
Staaf J; Lindgren D; Vallon-Christersson J; Isaksson A; Goransson H; Juliusson G; Rosenquist R; Hoglund M; Borg A; Ringner M
Article: HAEMATOLOGICA. 2007;92(11):1495-1504
Thioredoxin, produced by stromal cells retrieved from the lymph node microenvironment, rescues chronic lymphocytic leukemia cells from apoptosis in vitro
Backman E; Bergh A-C; Lagerdahl I; Rydberg B; Sundstrom C; Tobin G; Rosenquist R; Linderholm M; Rosen A
Article: BRITISH JOURNAL OF CANCER. 2007;97(6):769-777
Upregulation of bfl-1 is a potential mechanism of chemoresistance in B-cell chronic lymphocytic leukaemia
Olsson A; Norberg M; Okvist A; Derkow K; Choudhury A; Tobin G; Celsing F; Osterborg A; Rosenquist R; Jondal M; Osorio LM
Article: LEUKEMIA RESEARCH. 2007;31(9):1219-1230
Detailed assessment of copy number alterations revealing homozygous deletions in 1p and 13q in mantle cell lymphoma
Thelander EF; Ichimura K; Collins VP; Walsh SH; Barbany G; Hagberg A; Laurell A; Rosenquist R; Larsson C; Lagercrantz S
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2007;138(1):68-71
Mast cell infiltration is a favourable prognostic factor in diffuse large B-cell lymphoma
Hedstrom G; Berglund M; Molin D; Fischer M; Nilsson G; Thunberg U; Book M; Sundstrom C; Rosenquist R; Roos G; Erlanson M; Amini R-M; Enblad G
Article: CELL. 2007;129(5):879-890
Downregulation of death-associated protein kinase 1 (DAPK1) in chronic lymphocytic leukemia
Raval A; Tanner SM; Byrd JC; Angerman EB; Perko JD; Chen S-S; Hackanson B; Grever MR; Lucas DM; MatkoviC JJ; Lin TS; Kipps TJ; Murray F; Weisenburger D; Sanger W; Lynch J; Watson P; Jansen M; Yoshinaga Y; Rosenquist R; de Jong PJ; Coggill P; Beck S; Lynch H; de la Chapelle A; Plass C
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2007;78(4):283-289
Telomere length and correlation with histopathogenesis in B-cell leukemias/lymphomas
Walsh SH; Grabowski P; Berglund M; Thunberg U; Thorselius M; Tobin G; Aleskog A; Karlsson K; Sundstrom C; Laurell A; Enblad G; Rosenquist R; Roos G
Article: BLOOD. 2007;109(7):2989-2998
Comprehensive characterization of IGHV3-21-expressing B-cell chronic lymphocytic leukemia:: an Italian multicenter study
Bomben R; Dal Bo M; Capello D; Benedetti D; Marconi D; Zucchetto A; Forconi F; Maffei R; Ghia EM; Laurenti L; Bulian P; Del Principe MI; Palermo G; Thorselius M; Degan M; Campanini R; Guarini A; Del Poeta G; Rosenquist R; Efremov DG; Marasca R; Foa R; Gaidano G; Gattei V
Article: HEREDITARY CANCER IN CLINICAL PRACTICE. 2007;5(1):17-24
A hypothesis-generating search for new genetic breast cancer syndromes -: a national study in 803 Swedish families
von Wachenfeldt A; Lindblom A; Gronberg H; Einbeigi Z; Rosenquist R; Gardman C; Iselius L
Article: MODERN PATHOLOGY. 2007;20(1):63-75
Genomic imbalances during transformation from follicular lymphoma to diffuse large B-cell lymphoma
Berglund M; Enblad G; Thunberg U; Amini R-M; Sundstrom C; Roos G; Erlanson M; Rosenquist R; Larsson C; Lagercrantz S
Article: ARTHRITIS & RHEUMATOLOGY. 2006;54(12):3774-3781
Characteristics of diffuse large B cell lymphomas in rheumatoid arthritis
Baecklund E; Backlin C; Iliadou A; Granath F; Ekbom A; Amini R-M; Feltelius N; Enblad G; Sundstrom C; Klareskog L; Askling J; Rosenquist R
Article: BLOOD. 2006;107(7):2889-2894
Strikingly homologous immunoglobulin gene rearrangements and poor outcome inV_H3-21-using chronic lymphocytic leukemia patients independent of geographic origin and mutational status
Thorsélius M; Kröber A; Murray F; Thunberg U; Tobin G; Bühler A; Kienle D; Albesiano E; Maffei R; Dao-Ung LP; Wiley J; Vilpo J; Laurell A; Merup M; Roos G; Karlsson K; Chiorazzi N; Marasca R; Döhner H; Stilgenbauer S; Rosenquist R
Article: ARTHRITIS & RHEUMATOLOGY. 2006;54(3):692-701
Association of chronic inflammation, not its treatment, with increased lymphoma risk in rheumatoid arthritis
Baecklund E; Iliadou A; Askling J; Ekborn A; Backlin C; Granath F; Catrina AT; Rosenquist R; Feltelius N; Sundström C; Klareskog L
Article: LEUKEMIA. 2006;20(1):77-81
The G(-248)A polymorphism in the promoter region of the Bax gene does not correlate with prognostic markers or overall survival in chronic lymphocytic leukemia
Skogsberg Å; Tobin G; Kröber A; Kienle D; Thunberg U; Åleskog A; Karlsson K; Laurell A; Merup M; Vilpo J; Sundström C; Roos G; Jernerg-Wiklund H; Döhner H; Nilsson K; Stilgenbauer S; Rosenquist R
Article: LEUKEMIA. 2005;19(8):1452-1458
Insights into the multistep transformation process of lymphomas:: IgH-associated translocations and tumor suppressor gene mutations in clonally related composite Hodgkin's and non-Hodgkin's lymphomas
Schmitz R; Renné C; Rosenquist R; Tinguely M; Distler V; Menestrina F; Lestani M; Stankovic T; Austen B; Bräuninger A; Hansmann ML; Küppers R
Article: MODERN PATHOLOGY. 2005;18(8):1113-1120
Evaluation of immunophenotype in diffuse large B-cell lymphoma and its impact on prognosis
Berglund M; Thunberg U; Amini RM; Book M; Roos G; Erlanson M; Linderoth J; Dictor M; Jerkeman M; Cavallin-Ståhl E; Sundström C; Rehn-Eriksson S; Backlin C; Hagberg H; Rosenquist R; Enblad G
Article: BLOOD. 2005;106(2):681-689
Distinctive gene expression pattern in V_H3-21 utilizing B-cell chronic lymphocytic leukemia
Fält S; Merup M; Tobin G; Thunberg U; Gahrton G; Rosenquist R; Wennborg A
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2005;75(1):34-40
Mitogen induced activation, proliferation and surface antigen expression patterns in unmutated and hypermutated chronic lymphocytic leukemia cells
Vilpo J; Tobin G; Hulkkonen J; Hurme M; Thunberg U; Sundström C; Vilpo L; Rosenquist R
Article: LEUKEMIA RESEARCH. 2005;29(7):729-734
Lymphoplasmacytic lymphoma/Waldenstrom's macroglobulinemia derives from an extensively hypermutated B cell that lacks ongoing somatic hypermutation
Walsh SH; Laurell A; Sundström G; Roos L; Sundström C; Rosenquist R
Article: BLOOD. 2005;105(12):4807-4812
Telomere length as a prognostic parameter in chronic lymphocytic leukemia with special reference to V_H gene mutation status
Grabowski P; Hultdin M; Karlsson K; Tobin G; Åleskog A; Thunberg U; Laurell A; Sundström C; Rosenquist R; Roos G
Article: HAEMATOLOGICA. 2005;90(4):465-469
Patients with chronic lymphocytic leukemia with mutated V_H genes presenting with Binet stage B or C form a subgroup with a poor outcome
Tobin G; Thunberg U; Laurell A; Karlsson K; Aleskog A; Willander K; Soderberg O; Merup M; Vilpo J; Hultdin M; Sundstrom C; Roos G; Rosenquist R
Article: MODERN PATHOLOGY. 2005;18(3):331-339
Mantle cell lymphomas with clonal immunoglobulin V_H3-21 gene rearrangements exhibit fewer genomic imbalances than mantle cell lymphomas utilizing other immunoglobulin V_H genes
Thelander EF; Walsh SH; Thorsélius M; Laurell A; Landgren O; Larsson C; Rosenquist R; Lagercrantz S
Article: LEUKEMIA RESEARCH. 2005;29(2):153-158
Heterogeneous somatic hypermutation status confounds the cell of origin in hairy cell leukemia
Thorsélius M; Walsh SH; Thunberg U; Hagberg H; Sundström C; Rosenquist R
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2004;73(6):407-411
V_H gene mutation status and cellular drug resistance in chronic lymphocytic leukaemia
Åleskog A; Tobin G; Laurell A; Thunberg U; Lindhagen E; Roos G; Nilsson K; Nygren P; Sundström C; Höglund M; Larsson R; Rosenquist R
Article: LEUKEMIA AND LYMPHOMA. 2004;45(12):2451-2454
Similar humoral immunity parameters in chronic lymphocytic leukemia patients independent of V_H gene mutation status
Sinisalo M; Aittoniemi J; Koski T; Tobin G; Thunberg U; Sundström C; Rosenquist R; Käyhty H; Vilpo J
Article: BLOOD. 2004;104(9):2879-2885
Subsets with restricted immunoglobulin gene rearrangement features indicate a role for antigen selection in the development of chronic lymphocytic leukemia
Tobin G; Thunberg U; Karlsson K; Murray F; Laurell A; Willander K; Enblad G; Merup M; Vilpo J; Juliusson G; Sundström C; Söderberg O; Roos G; Rosenquist R
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2004;73(3):210-214
Clonally related splenic marginal zone lymphoma and Hodgkin lymphoma with unmutated V gene rearrangements and a 15-yr time gap between diagnoses
Rosenquist R; Roos G; Erlanson M; Küppers R; Bräuninger A; Hansmann ML
Article: CANCER GENETICS. 2004;153(1):69-72
Different gene expression in immunoglobulin-mutated and immunoglobulin-unmutated forms of chronic lymphocytic leukemia
Ferrer A; Ollila J; Tobin G; Nagy B; Thunberg U; Aalto Y; Vihinen M; Vilpo J; Rosenquist R; Knuutila S
Article: LEUKEMIA AND LYMPHOMA. 2004;45(2):221-228
V_H3-21 gene usage in chronic lymphocytic leukemia -: Characterization of a new subgroup with distinct molecular features and poor survival
Tobin G; Söderberg O; Thunberg U; Rosenquist R
Article: AMERICAN JOURNAL OF SURGICAL PATHOLOGY. 2003;27(11):1483-1488
Analysis of a clonally related mantle cell and Hodgkin lymphoma indicates Epstein-Barr virus infection of a Hodgkin/Reed-Sternberg cell precursor in a germinal center
Tinguely M; Rosenquist R; Sundström C; Amini RM; Küppers R; Hansmann ML; Bräuninger A
Article: GENES CHROMOSOMES AND CANCER. 2003;37(4):417-420
More extensive genetic alterations in unmutated than in hypermutated cases of chronic lymphocytic leukemia
Karhu R; Tobin G; Thunberg U; Vilpo L; Sundström C; Knuutila S; Rosenquist R; Vilpo J
Article: BLOOD. 2003;101(12):4952-4957
Chronic lymphocytic leukemias utilizing the V_H3-21 gene display highly restricted V_λ2-14 gene use and homologous CDR3s:: implicating recognition of a common antigen epitope
Tobin G; Thunberg U; Johnson A; Eriksson I; Söderberg O; Karlsson K; Merup M; Juliusson G; Vilpo J; Enblad G; Sundström C; Roos G; Rosenquist R
Article: BLOOD. 2003;101(10):4047-4054
Mutated V_H genes and preferential V_H3-21 use define new subsets of mantle cell lymphoma
Walsh SH; Thorsélius M; Johnson A; Söderberg O; Jerkernan M; Björck E; Eriksson I; Thunberg U; Landgren O; Ehinger M; Löfvenberg E; Wallman K; Enblad G; Sander B; Porwit-MacDonald A; Dictor M; Olofsson T; Sundström C; Roos G; Rosenquist R
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2003;121(4):566-577
Cytogenetic abnormalities in childhood acute myeloid leukaemia:: a Nordic series comprising all children enrolled in the NOPHO-93-AML trial between 1993 and 2001
Forestier E; Heim S; Blennow E; Borgström G; Holmgren G; Heinonen K; Johannsson J; Kerndrup G; Andersen MK; Lundin C; Nordgren A; Rosenquist R; Swolin B; Johansson B
Article: LEUKEMIA RESEARCH. 2003;27(4):337-341
Ex vivo drug and irradiation sensitivities in hypermutated and unmutated forms of chronic lymphocytic leukemia cells
Kivekäs I; Tobin G; Thunberg U; Vilpo L; Sundström C; Rosenquist R; Vilpo J
Article: BRITISH JOURNAL OF CANCER. 2003;88(4):593-598
Association between telomere length and V_H gene mutation status in chronic lymphocytic leukaemia:: clinical and biological implications
Hultdin M; Rosenquist R; Thunberg U; Tobin G; Norrback KF; Johnson A; Sundström C; Roos G
Article: ACTA ONCOLOGICA. 2003;42(7):726-734
Genetic counselling for cancer and risk perception
Lidén A; Berglund G; Hansson MG; Rosenquist R; Sjödén PO; Nordin K
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2003;70(1):53-59
Surface antigen expression and correlation with variable heavy-chain gene mutation status in chronic lymphocytic leukemia
Vilpo J; Tobin G; Hulkkonen J; Hurme M; Thunberg U; Sundström C; Vilpo L; Rosenquist R
Article: THE LANCET. 2002;360(9349):1935-1939
Polymorphism in the P2X7 receptor gene and survival in chronic lymphocytic leukaemia
Thunberg U; Tobin G; Johnson A; Söderberg O; Padyukov L; Hultdin M; Klareskog L; Enblad G; Sundström C; Roos G; Rosenquist R
Article: CANCER GENETICS. 2002;139(1):38-43
Clonal development of a blastoid mantle cell lymphoma studied with comparative genomic hybridization
Flordal E; Berglund M; Rosenquist R; Erlanson M; Enblad G; Roos G; Larsson C; Lagercrantz S
Article: LEUKEMIA AND LYMPHOMA. 2002;43(11):2179-2189
A novel B-cell line (U-2932) established from a patient with diffuse large B-cell lymphoma following Hodgkin lymphoma
Amini RM; Berglund M; Rosenquist R; Von Heideman A; Lagercrantz S; Thunberg U; Bergh J; Sundström C; Glimelius B; Enblad G
Article: EXPERIMENTAL HEMATOLOGY. 2002;30(10):1170-1177
Minimal residual disease quantification in childhood acute lymphoblastic leukemia by real-time polymerase chain reaction using the SYBR green dye
Li AH; Forestier E; Rosenquist R; Roos G
Article: JOURNAL OF MEDICAL GENETICS. 2002;39(9):689-694
Coping style, psychological distress, risk perception, and satisfaction in subjects attending genetic counselling for hereditary cancer
Nordin K; Lidén A; Hansson M; Rosenquist R; Berglund G
Article: MODERN PATHOLOGY. 2002;15(8):807-816
Chromosomal imbalances in diffuse large B-cell lymphoma detected by comparative genomic hybridization
Berglund M; Enblad G; Flordal E; Lui WO; Backlin C; Thunberg U; Sundström C; Roos G; Allander SV; Erlanson M; Rosenquist R; Larsson C; Lagercrantz S
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2002;68(4):217-224
Somatic hypermutation and V_H gene usage in mantle cell lymphoma
Thorsélius M; Walsh S; Eriksson I; Thunberg U; Johnson A; Backlin C; Enblad G; Sundström C; Roos G; Rosenquist R
Article: BLOOD. 2002;99(6):2262-2264
Somatically mutated Ig V_H3-21 genes characterize a new subset of chronic lymphocytic leukemia
Tobin G; Thunberg U; Johnson A; Thörn I; Söderberg O; Hultdin M; Botling J; Enblad G; Sällström J; Sundström C; Roos G; Rosenquist R
Article: LEUKEMIA RESEARCH. 2001;25(12):1033-1045
Detailed clonality analysis of relapsing precursor B acute lymphoblastic leukemia: implications for minimal residual disease detection
Li AH; Rosenquist R; Forestier E; Lindh J; Roos G
Article: BRITISH JOURNAL OF CANCER. 2000;82(3):601-607
Telomere length and telomerase activity in malignant lymphomas at diagnosis and relapse
Remes K; Norrback KF; Rosenquist R; Mehle C; Lindh J; Roos G
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 1999;63(4):211-218
Clonal rearrangements in childhood and adult precursor B acute lymphoblastic leukemia:: a comparative polymerase chain reaction study using multiple sets of primers
Li AH; Rosenquist R; Forestier E; Holmberg D; Lindh J; Löfvenberg E; Roos G
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 1999;63(3):171-179
Clonal evolution as judged by immunoglobulin heavy chain gene rearrangements in relapsing precursor-B acute lymphoblastic leukemia
Rosenquist R; Thunberg U; Li AH; Forestier E; Lönnerholm G; Lindh J; Sundström C; Sällstrom J; Holmberg D; Roos G
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 1999;62(2):123-128
V_H gene family utilization in different B-cell lymphoma subgroups
Rosenquist R; Lindström A; Holmberg D; Lindh J; Roos G
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 1998;61(3):164-172
Low rate of somatic hypermutations characterize progressive B-cell lymphomas
Rosenquist R; Lindström A; Li AH; Roos G; Lindh J; Holmberg D
Article: ACTA ONCOLOGICA. 1998;37(2):193-200
Alterations of the immunoglobulin heavy chain locus in progressive B-cell lymphomas
Rosenquist R; Linderholm B; Lindström A; Hagberg H; Sundström C; Roos G; Holmberg D; Lindh J
Article: DIAGNOSTIC MOLECULAR PATHOLOGY. 1997;6(3):140-146
Comparative analysis of detection systems for evaluation of PCR amplified immunoglobulin heavy-chain gene rearrangements
Thunberg U; Rosenquist R; Lindstrom A; Lindh J; Sundstrom C; Roos G; Sallstrom J
Article: MOLECULAR IMMUNOLOGY. 1997;34(4):305-313
Immunoglobulin V-H gene replacements in a T-cell lymphoblastic lymphoma
Rosenquist R; Lindh J; Roos G; Holmberg D
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All other publications

Review: LEUKEMIA. 2024;38(7):1455-1468
ERIC recommendations for TP53 mutation analysis in chronic lymphocytic leukemia-2024 update
Malcikova J; Pavlova S; Baliakas P; Chatzikonstantinou T; Tausch E; Catherwood M; Rossi D; Soussi T; Tichy B; Kater AP; Niemann CU; Davi F; Gaidano G; Stilgenbauer S; Rosenquist R; Stamatopoulos K; Ghia P; Pospisilova S
Review: HEMASPHERE. 2024;8(7):e113
Realizing precision medicine in chronic lymphocytic leukemia: Remaining challenges and potential opportunities
Stamatopoulos K; Pavlova S; Al-Sawaf O; Chatzikonstantinou T; Karamanidou C; Gaidano G; Cymbalista F; Kater AP; Rawstron A; Scarfo L; Ghia P; Rosenquist R
Editorial comment: BLOOD. 2024;143(17):1682-1684
New signature predicts MBL-to-CLL progression.
Rosenquist R
Review: MOLECULAR ASPECTS OF MEDICINE. 2024;96:101250
Current and emerging sequencing-based tools for precision cancer medicine.
Edsjö A; Gisselsson D; Staaf J; Holmquist L; Fioretos T; Cavelier L; Rosenquist R
Letter: LEUKEMIA. 2024;38(3):679-680
Updates of the ERIC recommendations on how to report the results from immunoglobulin heavy variable gene analysis in chronic lymphocytic leukemia
Chatzikonstantinou T; Agathangelidis A; Chatzidimitriou A; Tresoldi C; Davis Z; Giudicelli V; Kossida S; Belessi C; Rosenquist R; Ghia P; Langerak AW; Davi F; Stamatopoulos K
Review: BLOOD ADVANCES. 2023;7(23):7382-7383
Time to include IGLV3-21R110 status in CLL prognostication?
Rosenquist R
Review: JOURNAL OF INTERNAL MEDICINE. 2023;294(4):437-454
Implementation of precision medicine in healthcare-A European perspective
Stenzinger A; Moltzen EK; Winkler E; Molnar-Gabor F; Malek N; Costescu A; Jensen BN; Nowak F; Pinto C; Ottersen OP; Schirmacher P; Nordborg J; Seufferlein T; Froehling S; Edsjoe A; Garcia-Foncillas J; Normanno N; Lundgren B; Friedman M; Bolanos N; Tatton-Brown K; Hill S; Rosenquist R
Review: JOURNAL OF INTERNAL MEDICINE. 2023;294(4):413-436
Novel precision medicine approaches and treatment strategies in hematological malignancies
Rosenquist R; Bernard E; Erkers T; Scott DW; Itzykson R; Rousselot P; Soulier J; Hutchings M; Ostling P; Cavelier L; Fioretos T; Smedby KE
Corrigendum: LEUKEMIA. 2023;37(9):1944-1951
The 5th edition of The World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms (vol 36, pg 1720, 2022)
Alaggio R; Amador C; Anagnostopoulos I; Attygalle AD; de Oliveira Araujo IB; Berti E; Bhagat G; Borges AM; Boyer D; Calaminici M; Chadburn A; Chan JKC; Cheuk W; Chng W-J; Choi JK; Chuang S-S; Coupland SE; Czader M; Dave SS; de Jong D; Di Napoli A; Du M-Q; Elenitoba-Johnson KS; Ferry J; Geyer J; Gratzinger D; Guitart J; Gujral S; Harris M; Harrison CJ; Hartmann S; Hochhaus A; Jansen PM; Karube K; Kempf W; Khoury J; Kimura H; Klapper W; Kovach AE; Kumar S; Lazar AJ; Lazzi S; Leoncini L; Leung N; Leventaki V; Li X-Q; Lim MS; Liu W-P; Louissaint AJ; Marcogliese A; Medeiros LJ; Michal M; Miranda RN; Mitteldorf C; Montes-Moreno S; Morice W; Nardi V; Naresh KN; Natkunam Y; Ng S-B; Oschlies I; Ott G; Parrens M; Pulitzer M; Rajkumar SV; Rawstron AC; Rech K; Rosenwald A; Said J; Sarkozy C; Sayed S; Saygin C; Schuh A; Sewell W; Siebert R; Sohani AR; Suzuki R; Tooze R; Traverse-Glehen A; Vega F; Vergier B; Wechalekar AD; Wood B; Xerri L; Xiao W; Akinola NO; Akkari Y; Allende LM; Aozasa K; Araujo I; Arcaini L; Ardeshna KM; Asano N; Attarbaschi A; Bacon CM; Barrans SL; Batchelor T; Battistella M; Baughn LB; Behdad A; Berentsen S; Bianchi G; Bledsoe J; Borchmann P; Bower M; Buldini B; Burger JA; Burkhardt B; Cassaday RD; Cazzaniga G; Cerf-Bensussan N; Cesarman E; Chandy M; Chapman JR; Chapuy B; Chen X; Cheng CL; Chiattone C; Chiorazzi N; Cook LB; Cooper WA; Corboy GP; Cowan AJ; Cozzolino I; Cree IA; d'Amore ESG; Davies AJ; Deckert M; Delabie J; Demicco EG; Deshpande V; Diepstra A; Dierickx D; Dunleavy K; Eichhorst B; Ennishi D; Fajgenbaum DC; Farinha P; Fernandez de Larrea C; Fisher KE; Fitzgibbon J; Flanagan M; Fromm J; Garcia JF; Geddie WR; Gertz M; Gopal A; Gopal S; Greipp PT; Gru A; Gupta R; Hansmann M-L; Hebeda KM; Herfarth K; Herling M; Hermine O; Khe H-X; Hodge J; Hu S; Huang Y; Hung YP; Hunger S; Inaba H; Inagaki H; Iqbal J; Ishitsuka K; Iwaki N; Iwatsuki K; Jain N; Jeon YK; Kadin M; Kaji S; Kakkar A; Karadimitris A; Kataoka K; Kato S; Kersten MJ; Ketterling RP; Kim JE; Kratz CP; Kridel R; Kristinsson S; Kuppers R; Kuzu I; Yok-Lam; Lacasce A; Lamant-Rochaix L; Lamy T; Landgren O; Laskar S; Laskin WB; Lenz G; Li S; Di Li G; Lin P; Locatelli F; Lorsbach RB; Lossos I; Loughran TPJ; Macon WR; Maleszewski JJ; Malhotra P; Marafioti T; Maruyama D; Marx A; Mbulaiteye SM; Meignin V; Mejstrikova E; Michelow P; Miettinen M; Miles RR; Miyoshi H; Molina TJ; Mollejo M; Momose S; Mori T; Morice WG; Nadel B; Nagai H; Nagane M; Nair R; Nakamura N; Nakazawa A; Nasr S; Nicholson AG; Nicolae A; Ohgami RS; Oishi N; Olson TS; Ortonne N; Paiva B; Pan-Hammarstrom Q; Parihar M; Paulli M; Petersen A; Picarsic J; Pileri A; Pimpinelli N; Plaza JA; Rabin KR; Raderer M; Rai K; Randen U; Rao H; Robson A; Rochford R; Rosenquist R; Rossi D; Rossi ED; Rule S; Rymkiewicz G; Sabattini E; Saha V; Sakata-Yanagimoto M; Sander CA; Sangueza JM; Sangueza OP; Santucci M; Sato Y; Satou A; Schafernak KT; Schmitt F; Semenzato G; Sengar M; Shanafelt T; Shimada K; Slack GW; Slager S; Soffietti R; Solomon DA; Stamatopoulos K; Steidl C; Stilgenbauer S; Sukswai N; Takeuchi K; Tallini G; Tamaru J; Tan S-Y; Tembhare P; Tiacci E; Tokura Y; Tournilhac O; Treon S; Truemper L; Tsukasaki K; van Rhee F; Varghese A; Vermeer MH; Vielh P; Walker B; Wang M; Wang H-Y; Wang Z; Watanabe T; Weigert O; Wein-Stock D; Whittaker SJ; Willemze R; Woessmann W; Wu CJ; Yamaguchi M; Yamamoto H; Yamashita D; Yang S; Yang DT; Yasuda T; Yin W-H; Zen Y; Zhao S; Zhao W-L
Letter: ACTA ONCOLOGICA. 2023;62(6):560-564
The BioLymph study - implementing precision medicine approaches in lymphoma diagnostics, treatment and follow-up: feasibility and first results
Smedby KE; Waesterlid T; Tham E; Haider Z; Joelsson J; Thorvaldsdottir B; Krstic A; Wahlin BE; Foroughi-Asl H; Karlsson C; Eloranta S; Saft L; Palma M; Kwiecinska A; Hansson L; Osterborg A; Wirta V; Rassidakis G; Sander B; Sonnevi K; Rosenquist R
Corrigendum: LEUKEMIA. 2023;37(2):504
Different prognostic impact of recurrent gene mutations in chronic lymphocytic leukemia depending on IGHV gene somatic hypermutation status: a study by ERIC in HARMONY (Dec, 10.1038/s41375-022-01802-y, 2022)
Mansouri L; Thorvaldsdottir B; Sutton L-A; Karakatsoulis G; Meggendorfer M; Parker H; Nadeu F; Brieghel C; Laidou S; Moia R; Rossi D; Catherwood M; Kotaskova J; Delgado J; Rodriguez-Vicente AE; Benito R; Rigolin GM; Bonfiglio S; Scarfo L; Mattsson M; Davis Z; Gogia A; Rani L; Baliakas P; Foroughi-Asl H; Jylha C; Skaftason A; Rapado I; Miras F; Martinez-Lopez J; de la Serna J; Rivas JMH; Thornton P; Larrayoz MJ; Calasanz MJ; Fesus V; Matrai Z; Bodor C; Smedby KE; Espinet B; Puiggros A; Gupta R; Bullinger L; Bosch F; Tazon-Vega B; Baran-Marszak F; Oscier D; Nguyen-Khac F; Zenz T; Terol MJ; Cuneo A; Hernandez-Sanchez M; Pospisilova S; Mills K; Gaidano G; Niemann CU; Campo E; Strefford JC; Ghia P; Stamatopoulos K; Rosenquist R
Editorial comment: FRONTIERS IN ONCOLOGY. 2023;13:1252189
Editorial: The promise of immunogenetics for precision oncology
Vlachonikola E; Langerak AW; Rosenquist R; Chatzidimitriou A
Review: FRONTIERS IN ONCOLOGY. 2023;13:1143811
Recent revelations and future directions using single-cell technologies in chronic lymphocytic leukemia
Oder B; Chatzidimitriou A; Langerak AW; Rosenquist R; Osterholm C
Review: CAMBRIDGE PRISMS: PRECISION MEDICINE. 2023;1:e15
Building a precision medicine infrastructure at a national level: The Swedish experience.
Edsjö A; Lindstrand A; Gisselsson D; Mölling P; Friedman M; Cavelier L; Johansson M; Ehrencrona H; Fagerqvist T; Strid T; Lovmar L; Jacobsson B; Johansson Å; Engstrand L; Wheelock CE; Sikora P; Wirta V; Fioretos T; Rosenquist R; Genomic Medicine Sweden (GMS)
Review: FRONTIERS IN ONCOLOGY. 2023;13:1146486
Precision diagnostics in chronic lymphocytic leukemia: Past, present and future
Mollstedt J; Mansouri L; Rosenquist R
Letter: NATURE MEDICINE. 2022;28(10):1980-1982
Implementing precision medicine in a regionally organized healthcare system in Sweden
Fioretos T; Wirta V; Cavelier L; Berglund E; Friedman M; Akhras M; Botling J; Ehrencrona H; Engstrand L; Helenius G; Fagerqvist T; Gisselsson D; Gruvberger-Saal S; Gyllensten U; Heidenblad M; Hoglund K; Jacobsson B; Johansson M; Johansson A; Soller MJ; Landstrom M; Larsson P; Levin L-A; Lindstrand A; Lovmar L; Lyander A; Melin M; Nordgren A; Nordmark G; Molling P; Palmqvist L; Palmqvist R; Repsilber D; Sikora P; Stenmark B; Soderkvist P; Stranneheim H; Strid T; Wheelock CE; Wadelius M; Wedell A; Edsjo A; Rosenquist R
Editorial comment: SEMINARS IN CANCER BIOLOGY. 2022;84:1-2
Precision medicine in cancer: A paradigm shift
Rosenquist R; Frohling S; Stamatopoulos K
Review: SEMINARS IN CANCER BIOLOGY. 2022;84:32-39
Clinical utility of whole-genome sequencing in precision oncology
Rosenquist R; Cuppen E; Buettner R; Caldas C; Dreau H; Elemento O; Frederix G; Grimmond S; Haferlach T; Jobanputra V; Meggendorfer M; Mullighan CG; Wordsworth S; Schuh A
Review: SEMINARS IN CANCER BIOLOGY. 2022;84:16-22
Analytical demands to use whole-genome sequencing in precision oncology
Meggendorfer M; Jobanputra V; Wrzeszczynski KO; Roepman P; de Bruijn E; Cuppen E; Buttner R; Caldas C; Grimmond S; Mullighan CG; Elemento O; Rosenquist R; Schuh A; Haferlach T
Review: LEUKEMIA. 2022;36(8):1961-1968
Immunoglobulin gene sequence analysis in chronic lymphocytic leukemia: the 2022 update of the recommendations by ERIC, the European Research Initiative on CLL
Agathangelidis A; Chatzidimitriou A; Chatzikonstantinou T; Tresoldi C; Davis Z; Giudicelli V; Kossida S; Belessi C; Rosenquist R; Ghia P; Langerak AW; Davi F; Stamatopoulos K
Review: JOURNAL OF INTERNAL MEDICINE. 2022;292(2):221-242
Towards precision medicine in lymphoid malignancies
Buhler MM; Martin-Subero JI; Pan-Hammarstrom Q; Campo E; Rosenquist R
Editorial comment: BLOOD. 2021;138(23):2305-2307
The more complex, the worse outcome in CLL
Rosenquist R
Meeting abstract: BLOOD. 2021;138:3515
Mutations of the Novel Tumor Suppressor Gene SAMHD1 Are Frequent and Correlate with Decreased Protein Expression in Peripheral T-Cell Lymphomas (PTCL)
Kokaraki G; Xagoraris I; Da Silva PFN; Sutton LA; Falcao RM; de Souza JES; Osterborg A; Wirta V; Brandell RR; Rassidakis GZ
Editorial comment: JCO PRECISION ONCOLOGY. 2021;5:974-980
Discordant Reporting of a Previously CD Undescribed Pathogenic Germline BRCA2 Variant in Blood and Tumor Tissue in a Patient With Pancreatic Adenocarcinoma
Kordes M; Tamborero D; Lagerstedt-Robinson K; Yachnin J; Rosenquist R; Lohr J-M; Liljefors MG
Letter: LEUKEMIA AND LYMPHOMA. 2021;62(11):2808-2811
Mutations known from B-cell lymphoid malignancies are not found in CD34⁺ stem cells from patients with lymphoma
Husby S; Favero F; Rodriguez-Gonzalez FG; Sutton LA; Haastrup EK; Orskov AD; Hansen JW; Arboe B; Aslan D; Clasen-Linde E; Rahbek Gjerdrum LM; Gorlev JS; Brown P; Fischer-Nielsen A; Rosenquist R; Weischenfeldt J; Gronbaek K
Review: JOURNAL OF INTERNAL MEDICINE. 2021;290(3):602-620
Technological readiness and implementation of genomic-driven precision medicine for complex diseases
Franks PW; Melen E; Friedman M; Sundstrom J; Kockum I; Klareskog L; Almqvist C; Bergen SE; Czene K; Hagg S; Hall P; Johnell K; Malarstig A; Catrina A; Hagstrom H; Benson M; Smith JG; Gomez MF; Orho-Melander M; Jacobsson B; Halfvarson J; Repsilber D; Oresic M; Jern C; Melin B; Ohlsson C; Fall T; Ronnblom L; Wadelius M; Nordmark G; Johansson A; Rosenquist R; Sullivan PF
Letter: HEMASPHERE. 2021;5(3):e546
Assessing Patients' Knowledge on Chronic Lymphocytic Leukemia: Validation of the ERIC CLL Knowledge Questionnaire in Greece
Karamanidou C; Xochelli A; Papaioannou M; Moysiadis T; Scarfo L; Mattsson M; Stavroyianni N; Rosenquist R; Ghia P; Stamatopoulos K
Published conference paper: BLOOD. 2021;137(2):216-231
Triggering interferon signaling in T cells with avadomide sensitizes CLL to anti-PD-L1 /PD-1 immunotherapy
Ioannou N; Hagner PR; Stokes M; Gandhi AK; Apollonio B; Fanous M; Papazoglou D; Sutton L-A; Rosenquist R; Amini R-M; Chiu H; Lopez-Girona A; Janardhanan P; Awan FT; Jones J; Kay NE; Shanafelt TD; Tallman MS; Stamatopoulos K; Patten PEM; Vardi A; Ramsay AG
Editorial comment: HAEMATOLOGICA. 2019;104(10):1914-1916
p66Shc deficiency sets the scene for clinically aggressive chronic lymphocytic leukemia
Rosenquist R
Review: JOURNAL OF INTERNAL MEDICINE. 2019;286(2):118-136
Cell-free tumour DNA testing for early detection of cancer - a potential future tool
Barbany G; Arthur C; Lieden A; Nordenskjold M; Rosenquist R; Tesi B; Wallander K; Tham E
Letter: LEUKEMIA. 2019;33(7):1801-1805
Different time-dependent changes of risk for evolution in chronic lymphocytic leukemia with mutated or unmutated antigen B cell receptors
Moysiadis T; Baliakas P; Rossi D; Catherwood M; Strefford JC; Delgado J; Anagnostopoulos A; Belessi C; Stavroyianni N; Pospisilova S; Oscier D; Gaidano G; Campo E; Rosenquist R; Ghia P; Stamatopoulos K
Letter: HAEMATOLOGICA. 2019;104(5):e208-e210
Long-term real-world results of ibrutinib therapy in patients with relapsed or refractory chronic lymphocytic leukemia: 30-month follow up of the Swedish compassionate use cohort
Winqvist M; Andersson P-O; Asklid A; Karlsson K; Karlsson C; Lauri B; Lundin J; Mattsson M; Norin S; Sandstedt A; Rosenquist R; Spath F; Hansson L; Osterborg A
Review: HAEMATOLOGICA. 2018;103(12):1956-1968
TP53 aberrations in chronic lymphocytic leukemia: an overview of the clinical implications of improved diagnostics
Campo E; Cymbalista F; Ghia P; Jaeger U; Pospisilova S; Rosenquist R; Schuh A; Stilgenbauer S
Editorial comment: BLOOD. 2018;132(22):2317-2319
Not so lost in translation: RPS15 mutations in CLL
Ljungstrom V; Rosenquist R
Editorial comment: SEMINARS IN CANCER BIOLOGY. 2018;51:iv-v
Introduction: Epigenetics in cancer
Rosenquist R; Esteller M; Plass C
Review: LEUKEMIA. 2018;32(5):1070-1080
ERIC recommendations for TP53 mutation analysis in chronic lymphocytic leukemia-update on methodological approaches and results interpretation
Malcikova J; Tausch E; Rossi D; Sutton LA; Soussi T; Zenz T; Kater AP; Niemann CU; Gonzalez D; Davi F; Gonzalez Diaz M; Moreno C; Gaidano G; Stamatopoulos K; Rosenquist R; Stilgenbauer S; Ghia P; Pospisilova S
Letter: HAEMATOLOGICA. 2018;103(4):e158-e161
No improvement in long-term survival over time for chronic lymphocytic leukemia patients in stereotyped subsets #1 and #2 treated with chemo(immuno)therapy
Baliakas P; Mattsson M; Hadzidimitriou A; Minga E; Agathangelidis A; Sutton L-A; Scarfo L; Davis Z; Yan X-J; Plevova K; Sandberg Y; Vojdeman FJ; Tzenou T; Chu CC; Veronese S; Mansouri L; Smedby KE; Giudicelli V; Nguyen-Khac F; Panagiotidis P; Juliusson G; Anagnostopoulos A; Lefranc M-P; Trentin L; Catherwood M; Montillo M; Niemann CU; Langerak AW; Pospisilova S; Stavroyianni N; Chiorazzi N; Oscier D; Jelinek DF; Shanafelt T; Darzentas N; Belessi C; Davi F; Ghia P; Rosenquist R; Stamatopoulos K
Editorial comment: JOURNAL OF INTERNAL MEDICINE. 2017;282(5):358-359
Introduction to the symposium 'Targeted therapy in B-cell malignancies'
Smedby KE; Rosenquist R
Published conference paper: JOURNAL OF INTERNAL MEDICINE. 2017;282(5):371-394
Genetic landscape and deregulated pathways in B-cell lymphoid malignancies
Rosenquist R; Bea S; Du M-Q; Nadel B; Pan-Hammarstrom Q
Editorial comment: LEUKEMIA. 2017;31(7):1477-1481
Immunoglobulin gene sequence analysis in chronic lymphocytic leukemia: updated ERIC recommendations
Rosenquist R; Ghia P; Hadzidimitriou A; Sutton L-A; Agathangelidis A; Baliakas P; Darzentas N; Giudicelli V; Lefranc M-P; Langerak AW; Belessi C; Davi F; Stamatopoulos K
Editorial comment: HAEMATOLOGICA. 2017;102(6):968-971
Immunoglobulin genes in chronic lymphocytic leukemia: key to understanding the disease and improving risk stratification
Sutton L-A; Hadzidimitriou A; Baliakas P; Agathangelidis A; Langerak AW; Stilgenbauer S; Pospisilova S; Davis Z; Forconi F; Davi F; Ghia P; Rosenquist R; Stamatopoulos K
Review: LEUKEMIA. 2017;31(2):282-291
Antigen receptor stereotypy in chronic lymphocytic leukemia
Stamatopoulos K; Agathangelidis A; Rosenquist R; Ghia P
Editorial comment: CANCER CELL. 2016;30(5):665-667
Unraveling the DNA Methylome in Mantle Cell Lymphoma: New Insights into the Cellular Origin
Mansouri L; Rosenquist R
Review: HAEMATOLOGICA. 2016;101(9):1002-1009
Clinical impact of recurrently mutated genes on lymphoma diagnostics: state-of-the-art and beyond
Rosenquist R; Rosenwald A; Du M-Q; Gaidano G; Groenen P; Wotherspoon A; Ghia P; Gaulard P; Campo E; Stamatopoulos K
Letter: HAEMATOLOGICA. 2016;101(9):e369-e373
ATM mutations in major stereotyped subsets of chronic lymphocytic leukemia: enrichment in subset #2 is associated with markedly short telomeres
Navrkalova V; Young E; Baliakas P; Radova L; Sutton L-A; Plevova K; Mansouri L; Ljungstrom V; Ntoufa S; Davis Z; Juliusson G; Smedby KE; Belessi C; Panagiotidis P; Touloumenidou T; Davi F; Langerak AW; Ghia P; Strefford JC; Oscier D; Mayer J; Stamatopoulos K; Pospisilova S; Rosenquist R; Trbusek M
Editorial comment: SEMINARS IN CANCER BIOLOGY. 2016;39:1-2
B-cell malignancies: All roads lead to NF-κB activation
Rosenquist R; Stamatopoulos K
Review: SEMINARS IN CANCER BIOLOGY. 2016;39:40-48
NF-κB activation in chronic lymphocytic leukemia: A point of convergence of external triggers and intrinsic lesions
Mansouri L; Papakonstantinou N; Ntoufa S; Stamatopoulos K; Rosenquist R
Letter: HAEMATOLOGICA. 2016;101(7):e299-e302
Additional trisomies amongst patients with chronic lymphocytic leukemia carrying trisomy 12: the accompanying chromosome makes a difference
Baliakas P; Puiggros A; Xochelli A; Sutton L-A; Nguyen-Khac F; Gardiner A; Plevova K; Minga E; Hadzidimitriou A; Walewska R; McCarthy H; Ortega M; Collado R; Gonzalez T; Granada I; Luno E; Kotaskova J; Moysiadis T; Davis Z; Stavroyianni N; Anagnostopoulos A; Strefford JC; Pospisilova S; Davi F; Athanasiadou A; Rosenquist R; Oscier D; Espinet B; Stamatopoulos K
Editorial comment: BLOOD. 2016;127(17):2052-2054
Not all subclones matter in CLL
Sutton L-A; Rosenquist R
Review: JOURNAL OF INTERNAL MEDICINE. 2016;279(4):347-357
Prognostic indices in chronic lymphocytic leukaemia: where do we stand how do we proceed?
Baliakas P; Mattsson M; Stamatopoulos K; Rosenquist R
Editorial comment: HAEMATOLOGICA. 2016;101(3):263-265
Innovation In the prognostication of chronic lymphocytic leukemia: how far beyond TP53 gene analysis can we go?
Pospisilova S; Sutton L-A; Malcikova J; Tausch E; Rossi D; Montserrat E; Moreno C; Stamatopoulos K; Gaidano G; Rosenquist R; Ghia P
Editorial comment: LEUKEMIA AND LYMPHOMA. 2015;56(11):3008-3009
A new piece to the stereotypy "puzzle" in chronic lymphocytic leukemia
Rosenquist R
Review: SEMINARS IN CANCER BIOLOGY. 2015;34:22-35
The complex interplay between cell-intrinsic and cell-extrinsic factors driving the evolution of chronic lymphocytic leukemia
Sutton L-A; Rosenquist R
Letter: BLOOD. 2015;126(8):1043-1044
Prognostic relevance of MYD88 mutations in CLL: the jury is still out
Baliakas P; Hadzidimitriou A; Agathangelidis A; Rossi D; Sutton L-A; Kminkova J; Scarfo L; Pospisilova S; Gaidano G; Stamatopoulos K; Ghia P; Rosenquist R
Letter: LEUKEMIA. 2015;29(3):748-751
Common variation at 12q24.13 (OAS3) influences chronic lymphocytic leukemia risk
Sava GP; Speedy HE; Di Bernardo MC; Dyer MJS; Holroyd A; Sunter NJ; Marr H; Mansouri L; Deaglios S; Karabon L; Frydecka I; Jamroziak K; Woszczyk D; Juliusson G; Smedby KE; Jayne S; Majid A; Wang Y; Dearden C; Hall AG; Mainou-Fowler T; Jackson GH; Summerfield G; Harris RJ; Pettitt AR; Allsup DJ; Bailey JR; Pratt G; Pepper C; Fegan C; Rosenquist R; Catovsky D; Allan JM; Houlston RS
Review: EXPERT REVIEW OF HEMATOLOGY. 2015;8(1):71-78
Clonal evolution in chronic lymphocytic leukemia: impact of subclonality on disease progression
Sutton L-A; Rosenquist R
Review: HAEMATOLOGICA. 2015;100(1):7-16
Deciphering the molecular landscape in chronic lymphocytic leukemia: time frame of disease evolution
Sutton L-A; Rosenquist R
Review: CANCER RESEARCH. 2014;74(16):4211-4216
Immunogenetic Studies of Chronic Lymphocytic Leukemia: Revelations and Speculations about Ontogeny and Clinical Evolution
Vardi A; Agathangelidis A; Sutton L-A; Ghia P; Rosenquist R; Stamatopoulos K
Letter: BRITISH JOURNAL OF HAEMATOLOGY. 2014;166(4):621-625
The frequency of TP53 gene defects differs between chronic lymphocytic leukaemia subgroups harbouring distinct antigen receptors
Malcikova J; Stalika E; Davis Z; Plevova K; Trbusek M; Mansouri L; Scarfo L; Baliakas P; Gardiner A; Sutton L-A; Francova HS; Agathangelidis A; Anagnostopoulos A; Tracy I; Makris A; Smardova J; Ghia P; Belessi C; Gonzalez D; Rosenquist R; Oscier D; Pospisilova S; Stamatopoulos K
Letter: LEUKEMIA. 2014;28(3):710-713
On the way towards a 'CLL prognostic index': focus on TP53, BIRC3, SF3B1, NOTCH1 and MYD88 in a population-based cohort
Cortese D; Sutton L-A; Cahill N; Smedby KE; Geisler C; Gunnarsson R; Juliusson G; Mansouri L; Rosenquist R
Letter: LEUKEMIA. 2014;28(3):694-696
Feasibility of targeted next-generation sequencing of the TP53 and ATM genes in chronic lymphocytic leukemia
Mansouri L; Sutton L-A; Ljungstrom V; Sorqvist EF; Gunnarsson R; Smedby KE; Juliusson G; Stamatopoulos K; Nilsson M; Rosenquist R
Editorial comment: SEMINARS IN CANCER BIOLOGY. 2014;24:1-2
The microenvironment in lymphomas - Dissecting the complex crosstalk between tumor cells and 'by-stander' cells
Rosenquist R; Davi F; Ghia P
Review: SEMINARS IN CANCER BIOLOGY. 2014;24:61-70
Lymphoma development in patients with autoimmune and inflammatory disorders - What are the driving forces?
Baecklund E; Smedby KE; Sutton L-A; Askling J; Rosenquist R
Editorial comment: SEMINARS IN CANCER BIOLOGY. 2013;23(6):397-398
Antigens in lymphoma development-Current knowledge and future directions Introduction
Rosenquist R; Davi F; Stamatopoulos K
Review: SEMINARS IN CANCER BIOLOGY. 2013;23(6):399-409
Antigen selection in B-cell lymphomas-Tracing the evidence
Sutton L-A; Agathangelidis A; Belessi C; Darzentas N; Davi F; Ghia P; Rosenquist R; Stamatopoulos K
Review: LEUKEMIA AND LYMPHOMA. 2013;54(11):2351-2364
Prognostic markers and their clinical applicability in chronic lymphocytic leukemia: where do we stand?
Rosenquist R; Cortese D; Bhoi S; Mansouri L; Gunnarsson R
Review: LEUKEMIA AND LYMPHOMA. 2013;54(8):1583-1590
Exploring the genetic landscape in chronic lymphocytic leukemia using high-resolution technologies
Gunnarsson R; Mansouri L; Rosenquist R
Review: EPIGENETICS. 2013;8(2):138-148
Uncovering the DNA methylome in chronic lymphocytic leukemia
Cahill N; Rosenquist R
Letter: LEUKEMIA. 2013;27(2):512-514
NOTCH1 and SF3B1 mutations can be added to the hierarchical prognostic classification in chronic lymphocytic leukemia
Mansouri L; Cahill N; Gunnarsson R; Smedby KE; Tjonnfjord E; Hjalgrim H; Juliusson G; Geisler C; Rosenquist R
Letter: LEUKEMIA. 2013;27(2):510-512
Whole-genome-amplified DNA as a source for mutational analysis underestimates the frequency of mutations in pediatric acute myeloid leukemia
Rosenquist R; Ehrencrona H; Hasle H; Palle J; Kanduri M
Letter: LEUKEMIA. 2012;26(5):1127-1131
Antigen receptor stereotypy across B-cell lymphoproliferations: the case of IGHV4-59/IGKV3-20 receptors with rheumatoid factor activity
Kostareli E; Gounari M; Janus A; Murray F; Brochet X; Giudicelli V; Pospisilova S; Oscier D; Foroni L; di Celle PF; Tichy B; Pedersen LB; Jurlander J; Ponzoni M; Kouvatsi A; Anagnostopoulos A; Thompson K; Darzentas N; Lefranc M-P; Belessi C; Rosenquist R; Davi F; Ghia P; Stamatopoulos K
Review: EXPERT REVIEW OF HEMATOLOGY. 2012;5(1):69-79
RNA-based markers as prognostic factors in chronic lymphocytic leukemia
Sevov M; Rosenquist R; Mansouri L
Letter: BLOOD. 2012;119(4):1087-1088
High ERG gene expression is an unfavorable prognostic marker in pediatric acute myeloid leukemia Response
Staffas A; Kanduri M; Hovland R; Rosenquist R; Ommen HB; Abrahamsson J; Forestier E; Jahnukainen K; Jonsson OG; Zeller B; Palle J; Lonnerholm G; Hasle H; Ehrencrona H; Palmqvist L
Letter: LEUKEMIA. 2012;26(1):170-172
Coexistence of trisomies of chromosomes 12 and 19 in chronic lymphocytic leukemia occurs exclusively in the rare IgG-positive variant
Ibbotson R; Athanasiadou A; Sutton L-A; Davis Z; Gardiner A; Baliakas P; Gunnarsson R; Anagnostopoulos A; Juliusson G; Rosenquist R; Oscier D; Stamatopoulos K
Letter: LEUKEMIA. 2011;25(12):1904-1908
Impact of TP53 mutation and 17p deletion in mantle cell lymphoma
Halldorsdottir AM; Lundin A; Murray F; Mansouri L; Knuutila S; Sundstrom C; Laurell A; Ehrencrona H; Sander B; Rosenquist R
Review: SEMINARS IN CANCER BIOLOGY. 2011;21(5):299-307
Unlocking the secrets of immunoglobulin receptors in mantle cell lymphoma: Implications for the origin and selection of the malignant cells
Agathangelidis A; Hadzidimitriou A; Rosenquist R; Stamatopoulos K
Letter: LEUKEMIA AND LYMPHOMA. 2011;52(6):1146-1149
LMO2 protein expression predicts survival in patients with rheumatoid arthritis and diffuse large B-cell lymphoma
Baecklund E; Backlin C; Mansouri M; Klareskog L; Askling J; Iliadou AN; Enblad G; Lossos IS; Natkunam Y; Rosenquist R
Review: SEMINARS IN CANCER BIOLOGY. 2010;20(6):400-409
Antigens in chronic lymphocytic leukemia-Implications for cell origin and leukemogenesis
Rosen A; Murray F; Evaldsson C; Rosenquist R
Letter: LEUKEMIA. 2010;24(1):211-215
Large but not small copy-number alterations correlate to high-risk genomic aberrations and survival in chronic lymphocytic leukemia: a high-resolution genomic screening of newly diagnosed patients
Gunnarsson R; Isaksson A; Mansouri M; Goransson H; Jansson M; Cahill N; Rasmussen M; Staaf J; Lundin J; Norin S; Buhl AM; Smedby KE; Hjalgrim H; Karlsson K; Jurlander J; Juliusson G; Rosenquist R
Letter: LEUKEMIA AND LYMPHOMA. 2009;50(5):829-830
Infrequent occurrence of PIK3CA mutations in chronic lymphocytic leukemia
Marincevic M; Tobin G; Rosenquist R
Editorial comment: JOURNAL OF INTERNAL MEDICINE. 2008;264(6):512-513
Introduction: the role of inflammation, autoimmune disease and infectious agents in development of leukaemia and lymphoma
Rosenquist R
Letter: BLOOD. 2008;111(12):5756-5757
Or both? Response
Roos G; Rosenquist R; Stilgenbauer S
Review: LEUKEMIA AND LYMPHOMA. 2008;49(6):1042-1049
Molecular genetic characterization reveals new subsets of mantle cell lymphoma
Thelander EF; Rosenquist R
Review: GENES CHROMOSOMES AND CANCER. 2008;47(2):149-158
Clinical and cytogenetic features of pediatric dic(9;20)(p13.2;q11.2)-positive B-Cell precursor acute lymphoblastic leukemias:: A nordic series of 24 cases and review of the literature
Forestier E; Gauffin F; Andersen MK; Autio K; Borgstrom G; Golovleva I; Gustafsson B; Heim S; Heinonen K; Heyman M; Hovland R; Johannsson JH; Kerndrup G; Rosenquist R; Schoumans J; Swolin B; Johansson B; Nordgren A
Letter: LEUKEMIA. 2008;22(1):212-214
Determination of IGHV gene mutational status in chronic lymphocytic leukemia: bioinformatics advances meet clinical needs
Davi F; Rosenquist R; Ghia P; Belessi C; Stamatopoulos K
Letter: LEUKEMIA. 2007;21(12):2539-2540
Reply to 'Male preponderance in chronic lymphocytic leukemia utilizing IGHV1-69' When size of the sample matters
Ghia P; Belessi C; Davi F; Rosenquist R; Stamatopoulos K
Review: GENES CHROMOSOMES AND CANCER. 2007;46(5):440-450
Cytogenetic patterns in ETV6/RUNXI-positive pediatric B-cell precursor acute lymphoblastic leukemia:: A Nordic series of 245 cases and review of the literature
Forestier E; Andersen MK; Autio K; Blennow E; Borgstrom G; Golovleva I; Heim S; Heinonen K; Hovland R; Johannsson JH; Kerndrup G; Nordgren A; Rosenquist R; Swolin B; Johansson B
Editorial comment: LEUKEMIA. 2007;21(1):1-3
ERIC recommendations on IGHV gene mutational status analysis in chronic lymphocytic leukemia
Ghia P; Stamatopoulos K; Belessi C; Moreno C; Stilgenbauer S; Stevenson F; Davi F; Rosenquist R
Letter: BLOOD. 2006;108(10):3623-3624
Subtype preference of the BCL6_397G/C polymorphism in germinal-center and non-germinal-center subtypes of diffuse large B-cell lymphoma
Berglund M; Amini R-M; Book M; Rosenquist R; Roos G; Thunberg U
Review: HEMATOLOGICAL ONCOLOGY. 2006;24(1):7-13
What is the current evidence for antigen involvement in the development of chronic lymphocytic leukemia?
Tobin G; Rosén A; Rosenquist R
Letter: BLOOD. 2005;105(12):4894-4895
The interleukin-10 gene promoter polymorphism (-1082) does not correlate with clinical outcome in diffuse large B-cell lymphoma
Berglund M; Thunberg U; Roos G; Rosenquist R; Enblad G
Letter: LEUKEMIA. 2005;19(5):871-873
Mcl-1 gene promoter insertions do not correlate with disease outcome, stage or V_H gene mutation status in chronic lymphocytic leukaemia
Tobin G; Skogsberg Å; Thunberg U; Laurell A; Åleskog A; Merup M; Sundström C; Roos G; Nilsson K; Rosenquist R
Letter: LEUKEMIA. 2005;19(3):464
Absence of H2AX gene mutations in B-cell leukemias and lymphomas
Walsh SH; Rosenquist R
Review: MEDICAL ONCOLOGY. 2005;22(4):327-341
Immunoglobulin gene analysis of mature B-cell malignancies
Walsh SH; Rosenquist R
Review: MEDICAL ONCOLOGY. 2005;22(3):217-228
Prognostic usage of V_H gene mutation status and its surrogate markers and the role of antigen selection in chronic lymphocytic leukemia
Tobin G; Rosenquist R
Letter: BRITISH JOURNAL OF HAEMATOLOGY. 2004;125(6):815-817
Association of the 1513C polymorphism in the P2X7 gene with familial forms of chronic lymphocytic leukaemia
Dao-Ung LP; Fuller SJ; Sluyter R; SkarRatt KK; Thunberg U; Tobin G; Byth K; Ban M; Rosenquist R; Stewart GJ; Wiley JS
Review: CURRENT OPINION IN RHEUMATOLOGY. 2004;16(3):254-261
Rheumatoid arthritis and malignant lymphomas
Baecklund E; Askling J; Rosenquist R; Ekbom A; Klareskog L
Letter: THE LANCET. 2003;361(9367):1478-1479
P2X7 polymorphism and chronic lymphocytic leukaemia -: Reply
Thunberg U; Tobin G; Johnson A; Enblad G; Rosenquist R
Letter: BLOOD. 2002;100(3):1098-1099
IgV_H3-21 gene usage in chronic lymphocytic leukemia
Tobin G; Thunberg U; Johnson A; Söderberg O; Botling J; Enblad G; Sällström J; Sundström C; Roos G; Rosenquist R
Letter: BLOOD. 2001;97(6):1892-1894
CD38 expression is a poor predictor for V_H gene mutational status and prognosis in chronic lymphocytic leukemia
Thunberg U; Johnson A; Roos G; Thöm I; Tobin G; Sällström J; Sundström C; Rosenquist R
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Grants

The molecular landscape of chronic lymphocytic leukemia
Swedish Cancer Society
1 January 2018
The molecular landscape of chronic lymphocytic leukemia
Swedish Cancer Society
1 January 2017
The molecular landscape of chronic lymphocytic leukemia
Swedish Cancer Society
1 January 2016
Characterization of the molecular landscape in chronic lymphocytic leukemia
Swedish Cancer Society
1 January 2015
Characterization of the molecular landscape in chronic lymphocytic leukemia
Swedish Cancer Society
1 January 2014

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KNUT OCH ALICE WALLENBERGS STIFTELSE. 2018
Förfinar kunskapen om leukemi