Pernilla Lagergren

Pernilla Lagergren

Professor
Telefon: +46852482758
Besöksadress: Blombäcks väg 23, plan 4, 17177 Stockholm
Postadress: K1 Molekylär medicin och kirurgi, K1 MMK Kirurgisk vårdvetenskap, 171 76 Stockholm

Om mig

  • Forskargruppsledare för gruppen Kirurgisk vårdvetenskap

    Pernilla Lagergren (f Viklund) blev legitimerad sjuksköterska 1999 och medicine doktor 2006 på KI. Därefter genomförde hon en post-doc period under 1½ år vid University of Bristol, England 2006-2007. Hon blev docent 2010 och innehar sedan 2011 en heltidstjänst som professor vid KI. I mars 2018 tillträdde Lagergren en tjänst som professor vid Imperial College London i England på deltidsbasis.

Forskningsbeskrivning

  • Pernilla leder en egen forskargrupp kirurgisk vårdvetenskap. Hennes huvudsakliga forskningsområde är hälsorelaterad livskvalitet (HRQOL), främst hos patienter med cancer i matstrupen. Forskningen fokuserar bland annat på att hitta faktorer som påverkar HRQOL och återhämtningen efter behandling för cancer på kort och lång sikt och om mått på HRQOL kan användas som en prognostisk faktor. Vidare fokuserar forskningen på att utveckla användandet och bearbetningen av livskvalitetsdata för att underlätta tolkning av patientrapporterade mått. I sin framtida forskning kommer hon att studera situationen för patienter med matstrupscancer ut ett bredare perspektiv där flertalet aspekter som psykosociala faktorer, emotionell påverkan, coping, och stödbehov är några. Vidare kommer den fortsatta forskningen även inkludera patientens närstående och dess behov. Genom sin forskning hoppas hon att patienter som opereras för matstrupscancer ska få den hjälp de behöver för att deras livskvalitet och anpassning till livet efter operation ska kunna förbättras och att även deras närstående ges det stöd de behöver.

Undervisning

  • Docent i vårdvetenskap 2010

Artiklar

Alla övriga publikationer

Forskningsbidrag

  • Swedish Research Council
    1 January 2021 - 31 December 2023
  • The way forward after surgery for esophageal cancer
    Swedish Cancer Society
    1 January 2018
    Esophageal cancer has a worse prognosis than most tumor diseases and it often requires a very extensive surgery for chance of cure. The recovery after surgery is often long, troublesome and incomplete. It is important to identify influential factors that have a negative effect on the patient's quality of life after the operation. Weight loss and eating difficulties are central problems of the patients after surgery that need to be counteracted. Esophageal cancer is also a "family disease" and it is of great importance to examine the needs of relatives. The project is based on three nation-wide Swedish data collections on patients who are operated on for esophageal cancer. A group of patients participate in the planning of the studies. In a clinical trial, a 12-week physical exercise program is tested to counter muscle loss and improve quality of life. Several patient-reported measures such as quality of life, stress, anxiety, depression and weight are collected / measured from repeatedly after surgery. Furthermore, data on the patient, tumor, treatment, care time and survival are collected. The patient's relatives participate by answering several questions in order to improve their situation as well. Through studies of high scientific quality about important issues for patients, we want to demonstrate ways to how the healthcare system can provide the opportunity for better recovery in patients undergoing surgery for esophageal cancer and support for their relatives. Factors that affect the recovery should be identifiable at an early stage and guide an individual follow-up with targeted measures, including physical activity. This project can lead to patients who are operated for esophageal cancer receiving the support and help they need to optimize their quality of life and adaptation to post-operative life.
  • Swedish Research Council
    1 January 2018 - 31 December 2020
  • Swedish Research Council for Health Working Life and Welfare
    1 January 2018 - 31 December 2020
  • For a better life after surgery for esophageal cancer
    Swedish Cancer Society
    1 January 2017
    Esophageal cancer has a worse prognosis than most tumor diseases, and it often requires a very extensive surgery for cure and recovery after surgery is often long, cumbersome and incomplete. Weight loss and eating difficulties are central problems after the operation and therefore important to counteract. It is important to identify factors that have a negative effect on the patient's quality of life after surgery. Cancer is also a "family disease" and it is of great importance to examine the needs of relatives. The project is based on three nation-wide Swedish data collections as well as a data collection at a large center for esophageal cancer in London on patients undergoing surgery for esophageal cancer. We shall In a clinical trial test whether a physical exercise program can counter muscle loss. Data on several patient-reported measures such as quality of life, stress, anxiety, depression and weight are available from repeatedly after surgery. Furthermore, data on the patient, tumor, treatment, care time and survival are collected. The patient's relatives are invited to answer several questions in order to improve their situation as well. Through studies of high scientific quality about important issues for patients, we want to demonstrate ways to how the healthcare system can provide the opportunity for better recovery in patients undergoing surgery for esophageal cancer and support for their relatives. Factors that affect the recovery should be identifiable at an early stage and guide an individualized follow-up with targeted measures, among other things. physical activity. This project can lead to patients who are operated for esophageal cancer receiving the support and help they need to optimize their quality of life and adaptation to post-operative life.
  • For a better life after surgery for esophageal cancer
    Swedish Cancer Society
    1 January 2016
    Esophageal cancer has a worse prognosis than most tumor diseases, and it often requires a very extensive surgery for cure and recovery after surgery is often long, cumbersome and incomplete. Weight loss and eating difficulties are central problems after the operation and therefore important to counteract. It is important to identify factors that have a negative effect on the patient's quality of life after surgery. Cancer is also a "family disease" and it is of great importance to examine the needs of relatives. The project is based on three nation-wide Swedish data collections as well as a data collection at a large center for esophageal cancer in London on patients undergoing surgery for esophageal cancer. We shall In a clinical trial test whether a physical exercise program can counter muscle loss. Data on several patient-reported measures such as quality of life, stress, anxiety, depression and weight are available from repeatedly after surgery. Furthermore, data on the patient, tumor, treatment, care time and survival are collected. The patient's relatives are invited to answer several questions in order to improve their situation as well. Through studies of high scientific quality about important issues for patients, we want to demonstrate ways to how the healthcare system can provide the opportunity for better recovery in patients undergoing surgery for esophageal cancer and support for their relatives. Factors that affect the recovery should be identifiable at an early stage and guide an individualized follow-up with targeted measures, among other things. physical activity. This project can lead to patients who are operated for esophageal cancer receiving the support and help they need to optimize their quality of life and adaptation to post-operative life.
  • For a better life after surgery for esophageal cancer
    Swedish Cancer Society
    1 January 2015
    Esophageal cancer has a worse prognosis than most tumor diseases, and it often requires a very extensive surgery for cure and recovery after surgery is often long, cumbersome and incomplete. Weight loss and eating difficulties are central problems after the operation and therefore important to counteract. It is important to identify factors that have a negative effect on the patient's quality of life after surgery. Cancer is also a "family disease" and it is of great importance to examine the needs of relatives. The project is based on three nation-wide Swedish data collections as well as a data collection at a large center for esophageal cancer in London on patients undergoing surgery for esophageal cancer. We shall In a clinical trial test whether a physical exercise program can counter muscle loss. Data on several patient-reported measures such as quality of life, stress, anxiety, depression and weight are available from repeatedly after surgery. Furthermore, data on the patient, tumor, treatment, care time and survival are collected. The patient's relatives are invited to answer several questions in order to improve their situation as well. Through studies of high scientific quality about important issues for patients, we want to demonstrate ways to how the healthcare system can provide the opportunity for better recovery in patients undergoing surgery for esophageal cancer and support for their relatives. Factors that affect the recovery should be identifiable at an early stage and guide an individualized follow-up with targeted measures, among other things. physical activity. This project can lead to patients who are operated for esophageal cancer receiving the support and help they need to optimize their quality of life and adaptation to post-operative life.
  • Swedish Research Council
    1 January 2013 - 31 December 2015
  • Swedish Research Council
    1 January 2009 - 31 December 2012
  • Swedish Research Council
    1 January 2009 - 31 December 2012

Anställningar

  • Professor på deltid, Imperial College London, 2018-
  • Professor, Molekylär medicin och kirurgi, Karolinska Institutet, 2011-

Examina och utbildning

  • Docent, Vårdvetenskap, Karolinska Institutet, 2010
  • MEDICINE DOKTORSEXAMEN, Institutionen för molekylär medicin och kirurgi, Karolinska Institutet, 2006
  • Sjuksköterskeexamen, Hälsohögskolan, Umeå, 1999

Priser och utmärkelser

  • Hilda och Alfred Erikssons pris, Royal Swedish Academy of Sciences, 2020
  • Eric K. Fernströms pris för yngre, särskilt lovande och framgångsrika forskare vid Karolinska Institutet, Fernströms Foundation, 2018
  • Anders Jahres medicinska forskningspris för unga forskare (nordiskt pris), University of Oslo, 2015
  • Sven och Ebba-Christina Hagbergs forskningspris vid Karolinska Institutet, Sven och Ebba-Christina Hagbergs Stiftelse, 2012
  • Postdoktoralt stipendium från Svenska Sällskapet för Medicinsk Forskning, Swedish Society for Medical Research, 2007

Uppdrag i kommitté

  • Medlem, European Academy of Cancer Sciences, 2012-
  • Medlem, European Collaborative Group on Cancer Survivorship, European Collaborative Group on Cancer Survivorship, 2012-

Gästforskning och resestipendier

  • Gästprofessor vid King's College London, England, King's College London, 2013-2019
  • Post-doc, University of Bristol, 2006-2007

Nyheter från KI

Kalenderhändelser från KI