Pernilla Lagergren

Pernilla Lagergren

Professor
Telephone: +46852482758
Visiting address: Blombäcks väg 23, plan 4, 17177 Stockholm
Postal address: K1 Molekylär medicin och kirurgi, K1 MMK Kirurgisk vårdvetenskap, 171 76 Stockholm

About me

  • Research group leader of the group Surgical Care Science

    Pernilla Lagergren (born Viklund) became a registered nurse in 1999 and doctor of medicine (Ph.D.) in 2006 at KI. Thereafter, she conducted a post-doc period during 1 ½ years at the University of Bristol, England, in 2006-2007. She has an associate professorship since 2010 and in 2011 she was appointed a full-time position as a professor at KI. Since March 2018 she has a chair (permanent professor) in surgical care sciences at the Imperial College London, London, United Kingdom on a part-time basis.

Research

  • Pernilla leads her own research group within surgical care science. Her main research area is health-related quality of life (HRQOL), particularly in patients with cancer of the oesophagus. Her research focuses on factors influencing the HRQOL and recovery after surgical treatment for cancer in a short and long-term perspective. Moreover, she evaluates if HRQOL can be used as a prognostic factor. Further, her research involves methodological development of the use and management of HRQOL data with the aim of facilitating the interpretation of patient reported outcomes and improving the evaluation of potential confounding factors. Her future research will continue to focus mainly on patients with oesophageal cancer, and she will develop this area using patient-reported outcome measures where aspects of psychosocial distress, social support and coping are among other. Moreover, her future research aims to include patients family and their need of support. She hopes that the future research in this field will make a major contribution to improving the quality of life of oesophageal cancer patients and their closest family.

Teaching

  • Associate professor in care sciences 2010

Articles

All other publications

Grants

  • Swedish Research Council
    1 January 2021 - 31 December 2023
  • The way forward after surgery for esophageal cancer
    Swedish Cancer Society
    1 January 2018
    Esophageal cancer has a worse prognosis than most tumor diseases and it often requires a very extensive surgery for chance of cure. The recovery after surgery is often long, troublesome and incomplete. It is important to identify influential factors that have a negative effect on the patient's quality of life after the operation. Weight loss and eating difficulties are central problems of the patients after surgery that need to be counteracted. Esophageal cancer is also a "family disease" and it is of great importance to examine the needs of relatives. The project is based on three nation-wide Swedish data collections on patients who are operated on for esophageal cancer. A group of patients participate in the planning of the studies. In a clinical trial, a 12-week physical exercise program is tested to counter muscle loss and improve quality of life. Several patient-reported measures such as quality of life, stress, anxiety, depression and weight are collected / measured from repeatedly after surgery. Furthermore, data on the patient, tumor, treatment, care time and survival are collected. The patient's relatives participate by answering several questions in order to improve their situation as well. Through studies of high scientific quality about important issues for patients, we want to demonstrate ways to how the healthcare system can provide the opportunity for better recovery in patients undergoing surgery for esophageal cancer and support for their relatives. Factors that affect the recovery should be identifiable at an early stage and guide an individual follow-up with targeted measures, including physical activity. This project can lead to patients who are operated for esophageal cancer receiving the support and help they need to optimize their quality of life and adaptation to post-operative life.
  • Swedish Research Council
    1 January 2018 - 31 December 2020
  • Swedish Research Council for Health Working Life and Welfare
    1 January 2018 - 31 December 2020
  • For a better life after surgery for esophageal cancer
    Swedish Cancer Society
    1 January 2017
    Esophageal cancer has a worse prognosis than most tumor diseases, and it often requires a very extensive surgery for cure and recovery after surgery is often long, cumbersome and incomplete. Weight loss and eating difficulties are central problems after the operation and therefore important to counteract. It is important to identify factors that have a negative effect on the patient's quality of life after surgery. Cancer is also a "family disease" and it is of great importance to examine the needs of relatives. The project is based on three nation-wide Swedish data collections as well as a data collection at a large center for esophageal cancer in London on patients undergoing surgery for esophageal cancer. We shall In a clinical trial test whether a physical exercise program can counter muscle loss. Data on several patient-reported measures such as quality of life, stress, anxiety, depression and weight are available from repeatedly after surgery. Furthermore, data on the patient, tumor, treatment, care time and survival are collected. The patient's relatives are invited to answer several questions in order to improve their situation as well. Through studies of high scientific quality about important issues for patients, we want to demonstrate ways to how the healthcare system can provide the opportunity for better recovery in patients undergoing surgery for esophageal cancer and support for their relatives. Factors that affect the recovery should be identifiable at an early stage and guide an individualized follow-up with targeted measures, among other things. physical activity. This project can lead to patients who are operated for esophageal cancer receiving the support and help they need to optimize their quality of life and adaptation to post-operative life.
  • For a better life after surgery for esophageal cancer
    Swedish Cancer Society
    1 January 2016
    Esophageal cancer has a worse prognosis than most tumor diseases, and it often requires a very extensive surgery for cure and recovery after surgery is often long, cumbersome and incomplete. Weight loss and eating difficulties are central problems after the operation and therefore important to counteract. It is important to identify factors that have a negative effect on the patient's quality of life after surgery. Cancer is also a "family disease" and it is of great importance to examine the needs of relatives. The project is based on three nation-wide Swedish data collections as well as a data collection at a large center for esophageal cancer in London on patients undergoing surgery for esophageal cancer. We shall In a clinical trial test whether a physical exercise program can counter muscle loss. Data on several patient-reported measures such as quality of life, stress, anxiety, depression and weight are available from repeatedly after surgery. Furthermore, data on the patient, tumor, treatment, care time and survival are collected. The patient's relatives are invited to answer several questions in order to improve their situation as well. Through studies of high scientific quality about important issues for patients, we want to demonstrate ways to how the healthcare system can provide the opportunity for better recovery in patients undergoing surgery for esophageal cancer and support for their relatives. Factors that affect the recovery should be identifiable at an early stage and guide an individualized follow-up with targeted measures, among other things. physical activity. This project can lead to patients who are operated for esophageal cancer receiving the support and help they need to optimize their quality of life and adaptation to post-operative life.
  • For a better life after surgery for esophageal cancer
    Swedish Cancer Society
    1 January 2015
    Esophageal cancer has a worse prognosis than most tumor diseases, and it often requires a very extensive surgery for cure and recovery after surgery is often long, cumbersome and incomplete. Weight loss and eating difficulties are central problems after the operation and therefore important to counteract. It is important to identify factors that have a negative effect on the patient's quality of life after surgery. Cancer is also a "family disease" and it is of great importance to examine the needs of relatives. The project is based on three nation-wide Swedish data collections as well as a data collection at a large center for esophageal cancer in London on patients undergoing surgery for esophageal cancer. We shall In a clinical trial test whether a physical exercise program can counter muscle loss. Data on several patient-reported measures such as quality of life, stress, anxiety, depression and weight are available from repeatedly after surgery. Furthermore, data on the patient, tumor, treatment, care time and survival are collected. The patient's relatives are invited to answer several questions in order to improve their situation as well. Through studies of high scientific quality about important issues for patients, we want to demonstrate ways to how the healthcare system can provide the opportunity for better recovery in patients undergoing surgery for esophageal cancer and support for their relatives. Factors that affect the recovery should be identifiable at an early stage and guide an individualized follow-up with targeted measures, among other things. physical activity. This project can lead to patients who are operated for esophageal cancer receiving the support and help they need to optimize their quality of life and adaptation to post-operative life.
  • Swedish Research Council
    1 January 2013 - 31 December 2015
  • Swedish Research Council
    1 January 2009 - 31 December 2012
  • Swedish Research Council
    1 January 2009 - 31 December 2012

Employments

  • Professor on a part-time basis, Imperial College London, 2018-
  • Professor, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2011-

Degrees and Education

  • Docent, Karolinska Institutet, 2010
  • Doctor Of Philosophy, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2006
  • Registered nurse, Hälsohögskolan, Umeå, 1999

Distinction and awards

  • Hilda och Alfred Erikssons research prize, Royal Swedish Academy of Sciences, 2020
  • Recipient of Eric K. Fernströms research prize in medicine for young scientists at Karolinska Institutet, Fernströms Foundation, 2018
  • Anders Jahre's research prize in medicine for young scientists, University of Oslo, 2015
  • Sven and Ebba-Christina Hagbergs research prize, Sven och Ebba-Christina Hagberg's Foundation, 2012
  • Postdoctoral Stipend Award from the Swedish Society for Medical Research, Swedish Society for Medical Research, 2007

Committee work

  • Member, European Academy of Cancer Sciences, 2012-
  • Member, European Collaborative Group on Cancer Survivorship, European Collaborative Group on Cancer Survivorship, 2012-

Visiting research fellowships

  • Visiting professor at King's College, London, UK, King's College London, 2013-2019
  • Post-doc, University of Bristol, 2006-2007

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