Paweł Kozielewicz

Publikationer
Forskningsbidrag
CV
Populärvetenskap och samverkan

Artiklar

Article: BIOORGANIC CHEMISTRY. 2024;151:107681
New Smoothened ligands based on the purine scaffold as potential agents for treating pancreatic cancer
Espinosa-Bustos C; Bertrand J; Villegas-Menares A; Guerrero S; Di Marcotullio L; Navacci S; Schulte G; Kozielewicz P; Bloch N; Villela V; Paulino M; Kogan MJ; Cantero J; Salas CO
Article: BRITISH JOURNAL OF PHARMACOLOGY. 2024;181(20):3819-3835
NanoBiT- and NanoBiT/BRET-based assays allow the analysis of binding kinetics of Wnt-3a to endogenous Frizzled 7 in a colorectal cancer model
Gratz L; Sajkowska-Kozielewicz JJ; Wesslowski J; Kinsolving J; Bridge LJ; Petzold K; Davidson G; Schulte G; Kozielewicz P
Journal article: BRITISH JOURNAL OF PHARMACOLOGY. 2024
Progress on the development of Class A GPCR-biased ligands
Morales P; Scharf MM; Bermudez M; Egyed A; Franco R; Hansen OK; Jagerovic N; Jakubik J; Keseru GM; Kiss DJ; Kozielewicz P; Larsen O; Majellaro M; Mallo-Abreu A; Navarro G; Prieto-Diaz R; Rosenkilde MM; Sotelo E; Stark H; Werner T; Wingler LM
Journal article: SLAS DISCOVERY. 2024;29(6):100174
Application of FRET- and BRET-based live-cell biosensors in deorphanization and ligand discovery studies on orphan G protein-coupled receptors
Sajkowska JJ; Tsang CH; Kozielewicz P
Article: CELL REPORTS. 2024;43(2):113727
Structural and functional insight into the interaction of Clostridioides difficile toxin B and FZD7
Kinsolving J; Bous J; Kozielewicz P; Kosenina S; Shekhani R; Gratz L; Masuyer G; Wang Y; Stenmark P; Dong M; Schulte G
Article: BRITISH JOURNAL OF PHARMACOLOGY. 2023;180:S23-S144
The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors
Alexander SPH; Christopoulos A; Davenport AP; Kelly E; Mathie AA; Peters JA; Veale EL; Armstrong JF; Faccenda E; Harding SD; Davies JA; Abbracchio MP; Abraham G; Agoulnik A; Alexander W; Al-hosaini K; Back M; Baker JG; Barnes NM; Bathgate R; Beaulieu J-M; Beck-Sickinger AG; Behrens M; Bernstein KE; Bettler B; Birdsall NJM; Blaho V; Boulay F; Bousquet C; Brauner-Osborne H; Burnstock G; Calo G; Castano JP; Catt KJ; Ceruti S; Chazot P; Chiang N; Chini B; Chun J; Cianciulli A; Civelli O; Clapp LH; Couture R; Cox HM; Csaba Z; Dahlgren C; Dent G; Douglas SD; Dournaud P; Eguchi S; Escher E; Filardo EJ; Fong T; Fumagalli M; Gainetdinov RR; Garelja ML; de Gasparo M; Gerard C; Gershengorn M; Gobeil F; Goodfriend TL; Goudet C; Gratz L; Gregory KJ; Gundlach AL; Hamann J; Hanson J; Hauger RL; Hay DL; Heinemann A; Herr D; Hollenberg MD; Holliday ND; Horiuchi M; Hoyer D; Hunyady L; Husain A; Ijzerman AP; Inagami T; Jacobson KA; Jensen RT; Jockers R; Jonnalagadda D; Karnik S; Kaupmann K; Kemp J; Kennedy C; Kihara Y; Kitazawa T; Kozielewicz P; Kreienkamp H-J; Kukkonen JP; Langenhan T; Larhammar D; Leach K; Lecca D; Lee JD; Leeman SE; Leprince J; Li XX; Lolait SJ; Lupp A; Macrae R; Maguire J; Malfacini D; Mazella J; McArdle CA; Melmed S; Michel MC; Miller LJ; Mitolo V; Mouillac B; Mueller CE; Murphy PM; Nahon J-L; Ngo T; Norel X; Nyimanu D; O'Carroll A-M; Offermanns S; Panaro MA; Parmentier M; Pertwee RG; Pin J-P; Prossnitz ER; Quinn M; Ramachandran R; Ray M; Reinscheid RK; Rondard P; Rovati GE; Ruzza C; Sanger GJ; Schoeneberg T; Schulte G; Schulz S; Segaloff DL; Serhan CN; Singh KD; Smith CM; Stoddart LA; Sugimoto Y; Summers R; Tan VP; Thal D; Thomas WW; Timmermans PBMWM; Tirupula K; Toll L; Tulipano G; Unal H; Unger T; Valant C; Vanderheyden P; Vaudry D; Vaudry H; Vilardaga J-P; Walker CS; Wang JM; Ward DT; Wester H-J; Willars GB; Williams TL; Woodruff TM; Yao C; Ye RD
Article: NATURE COMMUNICATIONS. 2023;14(1):4573
Pathway selectivity in Frizzleds is achieved by conserved micro-switches defining pathway-determining, active conformations
Gratz L; Kowalski-Jahn M; Scharf MM; Kozielewicz P; Jahn M; Bous J; Lambert NA; Gloriam DE; Schulte G
Journal article: IUPHAR/BPS GUIDE TO PHARMACOLOGY CITE. 2023;2023(1)
Class Frizzled GPCRs in GtoPdb v.2023.1
Arthofer E; Dijksterhuis J; Grätz L; Hot B; Kozielewicz P; Lauth M; Olofsson J; Petersen J; Polonio T; Schulte G; Strakova K; Valnohova J; Wright S
Article: SCIENCE SIGNALING. 2023;16(779):eabo4974
WNT stimulation induces dynamic conformational changes in the Frizzled-Dishevelled interaction
Bowin C-F; Kozielewicz P; Gratz L; Kowalski-Jahn M; Schihada H; Schulte G
Article: METHODS IN MOLECULAR BIOLOGY. 2022;2374:195-204
NanoBRET and NanoBiT/BRET-Based Ligand Binding Assays Permit Quantitative Assessment of Small Molecule Ligand Binding to Smoothened.
Kozielewicz P; Schulte G
Article: BRITISH JOURNAL OF PHARMACOLOGY. 2021;178:S27-S156
THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors
Alexander SPH; Christopoulos A; Davenport AP; Kelly E; Mathie A; Peters JA; Veale EL; Armstrong JF; Faccenda E; Harding SD; Pawson AJ; Southan C; Davies JA; Abbracchio MP; Alexander W; Al-hosaini K; Baeck M; Barnes NM; Bathgate R; Beaulieu J-M; Bernstein KE; Bettler B; Birdsall NJM; Blaho V; Boulay F; Bousquet C; Braeuner-Osborne H; Burnstock G; Calo G; Castano JP; Catt K; Ceruti S; Chazot P; Chiang N; Chini B; Chun J; Cianciulli A; Civelli O; Clapp LH; Couture R; Csaba Z; Dahlgren C; Dent G; Singh KD; Douglas SD; Dournaud P; Eguchi S; Escher E; Filardo EJ; Fong T; Fumagalli M; Gainetdinov RR; de Gasparo M; Gerard C; Gershengorn M; Gobeil F; Goodfriend TL; Goudet C; Gregory KJ; Gundlach AL; Hamann J; Hanson J; Hauger RL; Hay DL; Heinemann A; Hollenberg MD; Holliday ND; Horiuchi M; Hoyer D; Hunyady L; Husain A; IJzerman AP; Inagami T; Jacobson KA; Jensen RT; Jockers R; Jonnalagadda D; Karnik S; Kaupmann K; Kemp J; Kennedy C; Kihara Y; Kitazawa T; Kozielewicz P; Kreienkamp H-J; Kukkonen JP; Langenhan T; Leach K; Lecca D; Lee JD; Leeman SE; Leprince J; Li XX; Williams TL; Lolait SJ; Lupp A; Macrae R; Maguire J; Mazella J; McArdle CA; Melmed S; Michel MC; Miller LJ; Mitolo V; Mouillac B; Mueller CE; Murphy P; Nahon J-L; Ngo T; Norel X; Nyimanu D; Ocarroll A-M; Offermanns S; Panaro MA; Parmentier M; Pertwee RG; Pin J-P; Prossnitz ER; Quinn M; Ramachandran R; Ray M; Reinscheid RK; Rondard P; Rovati GE; Ruzza C; Sanger GJ; Schoeneberg T; Schulte G; Schulz S; Segaloff DL; Serhan CN; Stoddart LA; Sugimoto Y; Summers R; Tan VP; Thal D; Thomas WW; Timmermans PMWM; Tirupula K; Tulipano G; Unal H; Unger T; Valant C; Vanderheyden P; Vaudry D; Vaudry H; Vilardaga J-P; Walker CS; Wang JM; Ward DT; Wester H-J; Willars GB; Woodruff TM; Yao C; Ye RD
Journal article: IUPHAR/BPS GUIDE TO PHARMACOLOGY CITE. 2021;2021(3)
Class Frizzled GPCRs in GtoPdb v.2021.3
Arthofer E; Dijksterhuis J; Hot B; Kozielewicz P; Lauth M; Olofsson J; Petersen J; Polonio T; Schulte G; Strakova K; Valnohova J; Wright S
Article: NATURE COMMUNICATIONS. 2021;12(1):3919
Residue 6.43 defines receptor function in class F GPCRs
Turku A; Schihada H; Kozielewicz P; Bowin C-F; Schulte G
Article: ACS PHARMACOLOGY AND TRANSLATIONAL SCIENCE. 2021;4(3):1235-1245
Quantitative Profiling of WNT-3A Binding to All Human Frizzled Paralogues in HEK293 Cells by NanoBiT/BRET Assessments
Kozielewicz P; Shekhani R; Moser S; Bowin C-F; Wesslowski J; Davidson G; Schulte G
Article: HANDBOOK OF EXPERIMENTAL PHARMACOLOGY. 2021;269:101-115
Employing Genetically Encoded, Biophysical Sensors to Understand WNT/Frizzled Interaction and Receptor Complex Activation.
Kozielewicz P; Schihada H; Schulte G
Article: MOLECULES. 2020;26(1):E143-143
Geissospermiculatine, a New Alkaloid from Geissospermum reticulatum Bark
Sajkowska-Kozielewicz JJ; Kozielewicz P; Makarova K; Stocki M; Barnes NM; Paradowska K
Journal article: FARMACJA POLSKA. 2020;76(10):592-599
Review of drugs currently used to treat pain in osteoarthritis
Kwas K; Mostowy M; Kozielewicz P; Sajkowska-Kozielewicz J
Article: EMBO REPORTS. 2020;21(8):e48882
Mitochondrial protein biogenesis in the synapse is supported by local translation
Kuzniewska B; Cysewski D; Wasilewski M; Sakowska P; Milek J; Kulinski TM; Winiarski M; Kozielewicz P; Knapska E; Dadlez M; Chacinska A; Dziembowski A; Dziembowska M
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2020;295(26):8759-8774
eGFP-tagged Wnt-3a enables functional analysis of Wnt trafficking and signaling and kinetic assessment of Wnt binding to full-length Frizzled
Wesslowski J; Kozielewicz P; Wang X; Cui H; Schihada H; Kranz D; Karuna PM; Levkin P; Gross JC; Boutros M; Schulte G; Davidson G
Article: NATURE COMMUNICATIONS. 2020;11(1):414
Structural insight into small molecule action on Frizzleds
Kozielewicz P; Turku A; Bowin C-F; Petersen J; Valnohova J; Canizal MCA; Ono Y; Inoue A; Hoffmann C; Schulte G
Article: MOLECULAR PHARMACOLOGY. 2020;97(1):23-34
A NanoBRET-Based Binding Assay for Smoothened Allows Real-time Analysis of Ligand Binding and Distinction of Two Binding Sites for BODIPY-cyclopamine
Kozielewicz P; Bowin C-F; Turku A; Schulte G
Article: BRITISH JOURNAL OF PHARMACOLOGY. 2019;176(Suppl 1):S21-S141
THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: G protein-coupled receptors
Alexander SPH; Christopoulos A; Davenport AP; Kelly E; Mathie A; Peters JA; Veale EL; Armstrong JF; Faccenda E; Harding SD; Pawson AJ; Sharman JL; Southan C; Davies JA; Arumugam TV; Bennett A; Sjogren B; Sobey C; Wong SS; Abbracchio MP; Alexander W; Al-hosaini K; Back M; Beaulieu J-M; Bernstein KE; Bettler B; Birdsall NJM; Blaho V; Bousquet C; Brauner-Osborne H; Burnstock G; Calo G; Castano JP; Catt KJ; Ceruti S; Chazot P; Chiang N; Chun J; Cianciulli A; Clapp LH; Couture R; Csaba Z; Dent G; Singh KD; Douglas SD; Dournaud P; Eguchi S; Escher E; Filardo E; Fong TM; Fumagalli M; Gainetdinov RR; de Gasparo M; Gershengorn M; Gobeil F; Goodfriend TL; Goudet C; Gregory KJ; Gundlach AL; Hamann J; Hanson J; Hauger RL; Hay D; Heinemann A; Hollenberg MD; Holliday ND; Horiuchi M; Hoyer D; Hunyady L; Husain A; Ijzerman AP; Inagami T; Jacobson KA; Jensen RT; Jockers R; Jonnalagadda D; Karnik S; Kaupmann K; Kemp J; Kennedy C; Kihara Y; Kozielewicz P; Kreienkamp H-J; Kukkonen JP; Langenhan T; Leach K; Lecca D; Lee JD; Leeman SE; Leprince J; Lolait SJ; Lupp A; Macrae R; Maguire J; Mazella J; McArdle CA; Melmed S; Michel MC; Miller L; Mitolo V; Mouillac B; Murphy PM; Nahon J-L; Norel X; Nyimanu D; O'Carroll A-M; Offermanns S; Panaro MA; Pertwee RG; Pin J-P; Prossnitz E; Ramachandran R; Reinscheid RK; Rondard P; Rovati GE; Ruzza C; Sanger G; Schoeneberg T; Schulte G; Schulz S; Segaloff DL; Serhan CN; Stoddart LA; Sugimoto Y; Summers R; Tan V; Thomas W; Timmermans PBMWM; Tirupula K; Tulipano G; Unal H; Unger T; Vanderheyden P; Vaudry D; Vaudry H; Vilardaga J-P; Walker CS; Ward DT; Wester H-J; Willars GB; Williams TL; Woodruff TM; Yao C; Aldrich RW; Becirovic E; Biel M; Catterall WA; Conner AC; Davies P; Delling M; Di Virgilio F; Falzoni S; George C; Goldstein SAN; Grissmer S; Ha K; Hammelmann V; Hanukoglu I; Jarvis M; Jensen AA; Kaczmarek LK; Kellenberger S; Kennedy C; King B; Lynch JW; Perez-Reyes E; Plant LD; Rash LD; Ren D; Sivilotti LG; Smart TG; Snutch TP; Tian J; Van den Eynde C; Vriens J; Wei AD; Winn BT; Wulff H; Xu H; Yue L; Zhang X; Zhu M; Coons L; Fuller P; Korach KS; Young M; Bryant C; Farndale RW; Hobbs A; Jarvis GE; MacEwan D; Monie TP; Waldman S; Beuve A; Boison D; Brouckaert P; Burnett JC; Burns K; Dessauer C; Friebe A; Garthwaite J; Gertsch J; Helsby N; Izzo AA; Koesling D; Kuhn M; Ostrom R; Papapetropoulos A; Potter LR; Pyne NJ; Pyne S; Russwurm M; Schmidt HHHW; Seifert R; Stasch J-P; Szabo C; van der Stelt M; van der Vliet A; Watts V; Anderson CMH; Broer S; Dawson P; Hagenbuch B; Hammond JR; Hancox J; Inui K-I; Kanai Y; Kemp S; Thwaites DT; Verri T
Journal article: IUPHAR/BPS GUIDE TO PHARMACOLOGY CITE. 2019;2019(4)
Class Frizzled GPCRs (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database
Arthofer E; Dijksterhuis J; Hot B; Kozielewicz PL; Lauth M; Olofsson J; Petersen J; Polonio T; Schulte G; Strakova K; Valnohova J; Wright S
Journal article: FARMACJA POLSKA. 2019;75(8):451-456
Class F GPCR – activation mechanism and pharmacology
Kozielewicz P; Owczarek K; Sajkowska-Kozielewicz JJ
Article: NATURE COMMUNICATIONS. 2019;10(1):667
A conserved molecular switch in Class F receptors regulates receptor activation and pathway selection
Wright SC; Kozielewicz P; Kowalski-Jahn M; Petersen J; Bowin C-F; Slodkowicz G; Marti-Solano M; Rodriguez D; Hot B; Okashah N; Strakova K; Valnohova J; Babu MM; Lambert NA; Carlsson J; Schulte G
Article: PHARMACOLOGY. 2019;104(5-6):377-382
Overexpression of Orphan Receptor GPR61 Increases cAMP Levels upon Forskolin Stimulation in HEK293 Cells: in vitro and in silico Validation of 5-(Nonyloxy)Tryptamine as a Low-Affinity Inverse Agonist
Kozielewicz P; Grafton G; Sajkowska-Kozielewicz JJ; Barnes NM
Article: CHEMISTRYSELECT. 2018;3(33):9743-9752
Naphthalene Peri Annelated N,N- and N,O-Heterocycles: The Effect of Heteroatom-Guided Peri-Fusion on Their Structure and Reactivity Profiles-A Theoretical Endoscopy
Tzeli D; Kozielewicz P; Zloh M; Antonow D; Tsoungas PG; Petsalakis ID
Article: FEBS OPEN BIO. 2017;7(12):1982-1993
N-glycosylation and expression in human tissues of the orphan GPR61 receptor
Kozielewicz P; Alomar H; Yusof S; Grafton G; Cooper AJ; Curnow SJ; Ironside JW; Pall H; Barnes NM
Article: STRUCTURAL CHEMISTRY. 2017;28(4):925-943
Intramolecular single H bonding vs bifurcation in tuning the conformation of 2,2'-dihydroxybenzophenone and its derivatives: a DFT insight
Tzeli D; Tsoungas PG; Petsalakis ID; Kozielewicz P
Article: CHEMISTRYSELECT. 2016;1(10):2426-2438
2, 2′-Dihydroxybenzophenones and Derivatives. Efficient Synthesis and Structure Endoscopy by DFT and NMR. Credentials as Potent Antiinflammatory Agents
Tzeli D; Kozielewicz P; Zervou M; Potamitis C; Kokkotou K; Rak B; Petrou A; Tsolaki E; Gavalas A; Geronikaki A; Petsalakis ID; Tsoungas PG
Article: OXIDATIVE MEDICINE AND CELLULAR LONGEVITY. 2016;2016:2573580
Antioxidant, Cytotoxic, and Antiproliferative Activities and Total Polyphenol Contents of the Extracts of Geissospermum reticulatum Bark
Sajkowska-Kozielewicz JJ; Kozielewicz P; Barnes NM; Wawer I; Paradowska K
Article: TETRAHEDRON. 2015;71(2):359-369
Intramolecular cyclization of β-nitroso-o-quinone methides. A theoretical endoscopy of a potentially useful innate 'reclusive' reaction
Tzeli D; Tsoungas PG; Petsalakis ID; Kozielewicz P; Zloh M
Article: STRUCTURAL CHEMISTRY. 2014;25(6):1837-1846
Arene-fused 1,2-oxazole N-oxides and derivatives. The impact of the N-O dipole and substitution on their aromatic character and reactivity profile. Can it be a useful structure in synthesis? A theoretical insight
Kozielewicz P; Tzeli D; Tsoungas PG; Zloh M
Article: STRUCTURAL CHEMISTRY. 2014;25(6):1711-1723
β-Nitroso-o-quinone methides: potent intermediates in organic chemistry and biology. The impact of the NO group on their structure and reactivity profile: a theoretical insight
Kozielewicz P; Tsoungas PG; Tzeli D; Petsalakis ID; Zloh M
Article: MONATSHEFTE FUR CHEMIE. 2014;145(7):1201-1211
Insights into mechanism of anticancer activity of pentacyclic oxindole alkaloids of Uncaria tomentosa by means of a computational reverse virtual screening and molecular docking approach
Kozielewicz P; Paradowska K; Eric S; Wawer I; Zloh M
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Alla övriga publikationer

Preprint: MEDRXIV. 2024
Identification and molecular characterization of missense mutations in orphan GPCR GPR61 occurring in severe obesity
Tsang CH; De Rosa A; Kozielewicz P
Review: TRENDS IN PHARMACOLOGICAL SCIENCES. 2024;45(5):419-429
Frizzleds act as dynamic pharmacological entities
Schulte G; Scharf MM; Bous J; Voss JH; Gratz L; Kozielewicz P
Preprint: RESEARCH SQUARE. 2024
SAG1.3-derived Frizzled-targeting negative allosteric modulators
Schulte G; Grätz L; Turku A; Kozielewicz P; Bowin C-F; Scharf M; Voss J; Kinsolving J; Shekhani R; Oliva-Vilarnau N; Koolmeister T; Körber M; Lauschke V; Löber S; Gmeiner P
Conference publication: BRITISH JOURNAL OF PHARMACOLOGY. 2023;180(4):479-480
NanoBiT/BRET assessment of eGFP-WNT-3A binding to FZD₇ in SW480 cells under endogenous promotion
Kozielewicz P; Gratz L; Sajkowska-Kozielewicz J; Moser S; Davidson G; Schulte G
Preprint: BIORXIV. 2022
WNT stimulation induced conformational dynamics in the Frizzled-Dishevelled interaction
Bowin C-F; Kozielewicz P; Grätz L; Kowalski-Jahn M; Schihada H; Schulte G
Preprint: BIORXIV. 2022
Receptor levels determine binding affinity of WNT-3A to Frizzled 7 in a colorectal cancer model
Grätz L; Sajkowska-Kozielewicz J; Wesslowski J; Petzold K; Davidson G; Schulte G; Kozielewicz P
Letter: CELL RESEARCH. 2021;31(12):1311-1314
Cryo-EM structure of constitutively active human Frizzled 7 in complex with heterotrimeric G_s
Xu L; Chen B; Schihada H; Wright SC; Turku A; Wu Y; Han G-W; Kowalski-Jahn M; Kozielewicz P; Bowin C-F; Zhang X; Li C; Bouvier M; Schulte G; Xu F
Review: BASIC AND CLINICAL PHARMACOLOGY AND TOXICOLOGY. 2020;126:17-24
Structural insight into Class F receptors - What have we learnt regarding agonist-induced activation?
Schulte G; Kozielewicz P
Review: MOLECULAR PHARMACOLOGY. 2020;97(2):62-71
Molecular Pharmacology of Class F Receptor Activation
Kozielewicz P; Turku A; Schulte G
Preprint: BIORXIV. 2019
Mitochondria biogenesis in the synapse is supported by local translation
Kuzniewska B; Cysewski D; Wasilewski M; Sakowska P; Milek J; Kulinski TM; Kozielewicz P; Dadlez M; Chacinska A; Dziembowski A; Dziembowska M
Preprint: BIORXIV. 2019
A NanoBRET-based binding assay for Smoothened allows real time analysis of small-molecule ligand binding and distinction of two separate ligand binding sites for BODIPY-cyclopamine
Kozielewicz P; Bowin C-F; Schulte G
Editorial comment: LIFE SCIENCES. 2019;225:132
Comment on: Triazoles bind the C-terminal domain of SMO: Illustration by docking and molecular dynamics simulations the binding between SMO and triazoles
Kozielewicz P
Conference publication: FEBS OPEN BIO. 2019;9:28-29
Mitochondria biogenesis in the synapse is supported by local translation
Kuzniewska B; Cysewski D; Sakowska P; Milek J; Wasilewski M; Winiarski M; Kulinski TM; Kozielewicz P; Knapska E; Chacinska A; Dziembowski A; Dziembowska M
Published conference paper: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2016;164:98-105
Novel vitamin D analogues; cytotoxic and anti-proliferative activity against a diffuse large B-cell lymphoma cell line and B-cells from healthy donors
Kozielewicz P; Grafton G; Kutner A; Curnow SJ; Gordon J; Barnes NM
Meeting abstract: PLANTA MEDICA. 2016;82:s1-s381
Analysis of impact of cytotoxic and antioxidant activities of the Jerusalem Balsams using chemometric methods
Sajkowska-Kozielewicz JJ; Kozielewicz P; Makarova K; Wawer I; Paradowska K
Meeting abstract: PLANTA MEDICA. 2016;82:s1-s381
Cytotoxic, anti-radical and reducing properties of ethanol bark extracts of Geissospermum reticulatum
Sajkowska-Kozielewicz JJ; Kozielewicz P; Barnes NM; Wawer I; Paradowska K

Forskningsbidrag

Targeting G protein-coupled receptors in cancers
Karolinska Institutet
10 October 2024 - 9 October 2027
GPR34, GPR65 och GPR183 som terapeutiska mĺl i blodcancer
Jeanssons Stiftelser
13 December 2023 - 12 December 2024
Defining the role of GPR34, GPR65 and GPR183 as therapeutic targets in blood cancers
Swedish Research Council
1 January 2023 - 31 December 2026

Anställningar

Biträdande Lektor, Fysiologi och farmakologi, Karolinska Institutet, 2023-2029
Researcher, Department of Physiology and Pharmacology, Karolinska Institutet, 2022-2023
Post-doctoral researcher, Department of Physiology and Pharmacology, Karolinska Institutet, 2017-2022

Examina och utbildning

Habilitation in Medical Sciences, Medical University of Lublin, 2022
PhD in Clinical and Experimental Medicine, University of Birmingham, 2017
Master's of Pharmacy, Medical University of Warsaw, 2013

Artiklar

Alla övriga publikationer

Forskningsbidrag

Anställningar

Examina och utbildning

Nyheter från KI

Kalenderhändelser från KI