Paweł Kozielewicz

I graduated with a Master’s of Pharmacy degree from the Medical University of Warsaw, Poland. Next, I did my PhD as a Marie Curie Fellow with Prof. Nicholas M. Barnes at the University of Birmingham and Celentyx Ltd., UK (immunological and neuropharmacological studies on therapeutical drugs and targets, including orphan G protein-coupled receptors, GPCRs).

I had my first post-doctoral stay in the lab of Prof. Agnieszka Chacinska at the IIMCB, Warsaw, Poland (protein biogenesis in synaptoneurosomes). In August 2017, I joined Prof. Gunnar Schulte's lab for my second post-doc (pharmacology of class F Frizzleds GPCRs).

In February 2022, I received a habilitation/higher doctorate, equivalent to docentur, in medical sciences from the Medical University of Lublin, Poland. 

In December 2023, I was appointed Assistant Professor, and since May 2024, I have been a team leader: please see Molecular pharmacology of GPCRs and external lab website.

In my post-doctoral research in the Schulte lab, I focused on exploring the pharmacology of class F (Frizzleds) GPCRs by employing structural-functional analysis. It can be argued that, given certain ambiguities which exist about the molecular mechanism of action of these proteins, Frizzleds are similar to another class of the seven transmembrane-spanning receptors: orphan GPCRs. As such, in my current research, I investigate the role of orphan GPCRs in health and disease. For several diseases, some previous findings about a few orphan GPCRs have not been followed up by more thorough reports. Hence, the precise nature of orphan GPCRs' signalling and its association with a diseased state at a molecular level remain largely unknown. I aim to address these gaps in knowledge to push novel opportunities for therapies.

Please check Molecular pharmacology of GPCRs website for more information.

Vacant positions

If you are a prospective postdoc with skills in GPCRs pharmacology, I am happy to support joint fellowship applications (e.g. Wenner-Gren, DFG - Deutsche Forschungsgemeinschaft), whether based on several developed projects or project ideas in my group, or centered around your concepts.

Administration and organisation at Karolinska Institutet:

2025 – present: Deputy Programme Director, The Master’s Programme in Translational Physiology and Pharmacology (4FF22)

2023 – present: Director of the Advanced Receptor Pharmacology course (4 hp); The Master’s Programme in Translational Physiology and Pharmacology (4FF22)

Teaching:

Currently:

1. The Bachelor's Programme in Biomedicine (1BI17) at Karolinska Institutet, Pharmacology and Toxicology course (1BI045) – seminars in a) receptor 
pharmacology and pharmacokinetics, and b) cardiovascular pharmacology, for the 2nd year students

2. The Medical Programme (2LA21) at Karolinska Institutet, Basic Science 1 (VetK):  Basic Science, the Medical Profession and Learning course (2LA000) – supervisor for a scientific literature work for the 1st year students

3. The Master’s Programme in Translational Physiology and Pharmacology (4FF22) at Karolinska Institutet: 
- Integrated Physiology and Pharmacology course (4FF000), the 1st semester – lecturer and instructor at a workshop in pharmacokinetics, pharmacogenetics, and pharmacodynamics 
- Bioinformatics from a physiological and pharmacological perspective course  (4FF004), the 2nd semester – instructor during GPCRmd database workshop 
- Physiological and Pharmacological Mechanisms and Experimental  Approaches course (4FF002), the 2nd semester – lecturer in ligand-receptor binding,   instructor for the laboratory-based activities, evaluator of the laboratory group report, evaluator of the written exam 
- Advanced Receptor Pharmacology course (4FF008) for the 2nd year students – lecturer, instructor at seminars, workshops and laboratory-based activities, and examiner for the oral presentations and group reports

4. PhD course H9F3049 Cellular Signalling at Karolinska Institutet - lecturer in G protein-coupled receptors in cancer

5. PhD course in Biomolecular Sciences at the University of Campania Luigi Vanvitelli, Caserta, Italy - lecturer in Targeting understudied G protein-coupled receptors in therapy

In the past:

The old Medical Programme (2LK13) at Karolinska Institutet (2019-2022), BSc (Hons) Biomedical Science programme (B900) at the University of Birmingham (2014-2016).

Teaching and supervision/research management training:

At Karolinska Institutet:

2025 – completion of Two2Tango course (2 weeks)

2023 – completion of Introductory Doctoral Supervision course (1 week)

2022 – completion of a Teaching and Learning in Higher Education, distance course (Grundläggande högskolepedagogik, distant, 5 weeks)

Completion of KI Canvas courses: GOTeacher!, Bias in Assessment, Designing Assessments.

At the University of Nottingham: 2025 – completion of Blended and Hybrid Learning Design in Higher Education course

At the University of Colorado: 2021 – completion of Researcher Management and Leadership Training course

At the University of Birmingham: 2015 – completion of ILT001: Introduction to Learning and Teaching in Higher Education for Postgraduates course