Ning Xu Landén

Om mig
Publikationer
CV
Populärvetenskap och samverkan

Om mig

Docent i experimentell dermatologi och venereologi, 2017. Det finns mer
information som presenteras på sidan på engelska och
på http://www.xulandenlab.com [1]
[1] http://www.xulandenlab.com

Forskningsbeskrivning

Både kroniska svårläkta sår och psoriasis är utbredda sjukdomar som
medför stegrande hälso- och ekonomiska bördor över hela världen i brist
på effektiv behandling. Undersökning av rollen av regulatoriska RNA, till
exempel mikroRNA och långa icke-kodande RNA, utgör ett växande koncept och
ett lovande område för farmaceutiskt ingrepp. Målet för vårt
laboratorium är att fastställa hur regulatoriska RNA påverkar huden vid
sårläkning och vid psoriasis. Dessutom strävar vi efter att tillämpa
grundläggande vetenskapliga fynd som terapeutiska ingrepp för patienter.

Utvalda publikationer

Article: CELL STEM CELL. 2024;:S1934-5909(24)00412-0
Spatiotemporal single-cell roadmap of human skin wound healing.
Liu Z; Bian X; Luo L; Björklund ÅK; Li L; Zhang L; Chen Y; Guo L; Gao J; Cao C; Wang J; He W; Xiao Y; Zhu L; Annusver K; Gopee NH; Basurto-Lozada D; Horsfall D; Bennett CL; Kasper M; Haniffa M; Sommar P; Li D; Landén NX
Article: NATURE COMMUNICATIONS. 2024;15(1):9286
Epigenetic memory of radiotherapy in dermal fibroblasts impairs wound repair capacity in cancer survivors
Bian X; Piipponen M; Liu Z; Luo L; Geara J; Chen Y; Sangsuwan T; Maselli M; Diaz C; Bain CA; Eenjes E; Genander M; Crichton M; Cash JL; Archambault L; Haghdoost S; Fradette J; Sommar P; Halle M; Landen NX
Article: BRITISH JOURNAL OF DERMATOLOGY. 2024;:S251
Circular RNA circASH1L(4,5) protects microRNA-129-5p from target-directed microRNA degradation in human skin wound healing
Wang Q; Niu G; Liu Z; Toma MA; Geara J; Bian X; Zhang L; Piipponen M; Li D; Wang A; Sommar P; Xu Landen N
Article: NATURE COMMUNICATIONS. 2024;15(1):8637
The lncRNA SNHG26 drives the inflammatory-to-proliferative state transition of keratinocyte progenitor cells during wound healing.
Li D; Liu Z; Zhang L; Bian X; Wu J; Li L; Chen Y; Luo L; Pan L; Kong L; Xiao Y; Wang J; Zhang X; Wang W; Toma M; Piipponen M; Sommar P; Xu Landén N
Article: CELL DEATH AND DIFFERENTIATION. 2023;30(5):1334-1348
Human skin specific long noncoding RNA HOXC13-AS regulates epidermal differentiation by interfering with Golgi-ER retrograde transport
Zhang L; Piipponen M; Liu Z; Li D; Bian X; Niu G; Geara J; Toma MA; Sommar P; Landen NX
Article: COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY. 2022;14(9):a041230
Beyond the Code: Noncoding RNAs in Skin Wound Healing
Li D; Niu G; Landen NX
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2019;116(19):9443-9452
Human skin long noncoding RNA WAKMAR1 regulates wound healing by enhancing keratinocyte migration
Li D; Kular L; Vij M; Herter EK; Li X; Wang A; Chu T; Toma M-A; Zhang L; Liapi E; Mota A; Blomqvist L; Serezal IG; Rollman O; Wikstrom JD; Bienko M; Berglund D; Stahle M; Sommar P; Jagodic M; Landen NX
Review: CELLULAR AND MOLECULAR LIFE SCIENCES. 2016;73(20):3861-3885
Transition from inflammation to proliferation: a critical step during wound healing
Landen NX; Li D; Stahle M
Article: JOURNAL OF CLINICAL INVESTIGATION. 2015;125(8):3008-3026
MicroRNA-132 enhances transition from inflammation to proliferation during wound healing
Li D; Wang A; Liu X; Meisgen F; Gruenler J; Botusan IR; Narayanan S; Erikci E; Li X; Blomqvist L; Du L; Pivarcsi A; Sonkoly E; Chowdhury K; Catrina S-B; Stahle M; Landen NX

Artiklar

Article: BRITISH JOURNAL OF DERMATOLOGY. 2024;191(4):635-637
Single-cell transcriptomic analysis identifies infiltrating plasmacytoid dendritic cells in psoriasis epidermis
Luo L; Cheng H; Liu Z; Olszewski P; Pasquali L; Xu N; Enge M; Pivarcsi A; Sonkoly E
Article: FRONTIERS IN SURGERY. 2024;11:1349135
Single-cell profiling and functional screening reveal crucial roles for lncRNAs in the epidermal re-epithelialization of human acute wounds
Xiao Y; Zhang C; Liu X; Yang Y; Landen NX; Zhang Z; Li D
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2022;142(10):2793-2804.e26
Circular RNA Signatures of Human Healing and Nonhealing Wounds
Toma MA; Liu Z; Wang Q; Zhang L; Li D; Sommar P; Landen NX
Article: ELIFE. 2022;11:e80322
Integrative small and long RNA omics analysis of human healing and nonhealing wounds discovers cooperating microRNAs as therapeutic targets
Liu Z; Zhang L; Toma MA; Li D; Bian X; Pastar I; Tomic-Canic M; Sommar P; Xu Landen N
Article: SCIENCE. 2022;377(6602):eabg9302
Interleukin-17 governs hypoxic adaptation of injured epithelium
Konieczny P; Xing Y; Sidhu I; Subudhi I; Mansfield KP; Hsieh B; Biancur DE; Larsen SB; Cammer M; Li D; Landen NX; Loomis C; Heguy A; Tikhonova AN; Tsirigos A; Naik S
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2022;142(3 PT A):705-716
Single-Cell Analysis Reveals Major Histocompatibility Complex II-Expressing Keratinocytes in Pressure Ulcers with Worse Healing Outcomes
Li D; Cheng S; Pei Y; Sommar P; Karner J; Herter EK; Toma MA; Zhang L; Pham K; Cheung YT; Liu Z; Chen X; Eidsmo L; Deng Q; Landen NX
Article: CLINICAL EPIGENETICS. 2021;13(1):161
DNA methylome profiling reveals epigenetic regulation of lipoprotein-associated phospholipase A₂ in human vulnerable atherosclerotic plaque
Li J; Zhang X; Yang M; Yang H; Xu N; Fan X; Liu G; Jiang X; Fan J; Zhang L; Zhang H; Zhou Y; Li R; Gao S; Jin J; Jin Z; Zheng J; Tu Q; Ren J
Journal article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2021;141(5):s111
640 Single-cell transcriptomics of human pressure ulcers reveals MHCII expressing keratinocytes in patients with a worse healing outcome
Li D; Cheng S; Deng Q; Landén NX
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2021;141(3):659-671
miR-19a/b and miR-20a Promote Wound Healing by Regulating the Inflammatory Response of Keratinocytes
Li D; Peng H; Qu L; Sommar P; Wang A; Chu T; Li X; Bi X; Liu Q; Serezal IG; Rollman O; Lohcharoenkal W; Zheng X; Angelstig SE; Grunler J; Pivarcsi A; Sonkoly E; Catrina S-B; Xiao C; Stahle M; Mi Q-S; Zhou L; Landen NX
Article: METHODS IN MOLECULAR BIOLOGY. 2021;2193:67-75
Evaluation of MicroRNA Therapeutic Potential Using the Mouse In Vivo and Human Ex Vivo Wound Models.
Li X; Xu Landén N
Article: COMMUNICATIONS BIOLOGY. 2020;3(1):768
HypoxamiR-210 accelerates wound healing in diabetic mice by improving cellular metabolism
Narayanan S; Angelstig SE; Xu C; Grunler J; Zhao A; Zhu W; Landen NX; Stahle M; Zhang J; Ivan M; Maltesen RG; Botusan IR; Ekberg NR; Zheng X; Catrina S-B
Article: ADVANCES IN WOUND CARE. 2020;9(4):145-160
Circular RNA hsa_circ_0084443 Is Upregulated in Diabetic Foot Ulcer and Modulates Keratinocyte Migration and Proliferation
Wang A; Toma MA; Ma J; Li D; Vij M; Chu T; Wang J; Li X; Landen NX
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2020;140(2):465-476.e11
MicroRNA-34 Family Enhances Wound Inflammation by Targeting LGR4
Wu J; Li X; Li D; Ren X; Li Y; Herter EK; Qian M; Toma M-A; Wintler A-M; Serezal IG; Rollman O; Stahle M; Wikstrom JD; Ye X; Landen NX
Article: METHODS IN MOLECULAR BIOLOGY. 2020;2154:239-247
Investigation of Skin Wound Healing Using a Mouse Model.
Wu J; Landén NX
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2019;139(6):1373-1384
WAKMAR2, a Long Noncoding RNA Downregulated in Human Chronic Wounds, Modulates Keratinocyte Motility and Production of Inflammatory Chemokines
Herter EK; Li D; Toma MA; Vij M; Li X; Visscher D; Wang A; Chu T; Sommar P; Blomqvist L; Berglund D; Stahle M; Wikstrom JD; Landen NX
Article: ACTA DERMATO-VENEREOLOGICA. 2019;99(2):196-205
The Keratinocyte Transcriptome in Psoriasis: Pathways Related to Immune Responses, Cell Cycle and Keratinization
Pasquali L; Srivastava A; Meisgen F; Das Mahapatra K; Xia P; Landen NX; Pivarcsi A; Sonkoly E
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2018;138(8):1754-1763
Resident T Cells in Resolved Psoriasis Steer Tissue Responses that Stratify Clinical Outcome
Serezal IG; Classon C; Cheuk S; Barrientos-Somarribas M; Wadman E; Martini E; Chang D; Landen NX; Ehrstrom M; Nylen S; Eidsmo L
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2018;138(4):882-892
Genome-Wide Screen for MicroRNAs Reveals a Role for miR-203 in Melanoma Metastasis
Lohcharoenkal W; Das Mahapatra K; Pasquali L; Crudden C; Kular L; Ulum YZA; Zhang L; Landen NX; Girnita L; Jagodic M; Stahle M; Sonkoly E; Pivarcsi A
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2017;137(12):2630-2638
MicroRNA-132 with Therapeutic Potential in Chronic Wounds
Li X; Li D; Wang A; Chu T; Lohcharoenkal W; Zheng X; Grunler J; Narayanan S; Eliasson S; Herter EK; Wang Y; Ma Y; Ehrstrom M; Eidsmo L; Kasper M; Pivarcsi A; Sonkoly E; Catrina S-B; Stahle M; Landen NX
Article: SCIENTIFIC REPORTS. 2017;7(1):7797
MicroRNA-132 promotes fibroblast migration via regulating RAS p21 protein activator 1 in skin wound healing
Li X; Li D; Wikstrom JD; Pivarcsi A; Sonkoly E; Stahle M; Landen NX
Journal article: JOURNAL OF BURN CARE & RESEARCH. 2017;38(4):251-259
Intratracheal Instillation of Perfluorohexane Modulates the Pulmonary Immune Microenvironment by Attenuating Early Inflammatory Factors in Patients With Smoke Inhalation Injury: A Randomized Controlled Clinical Trial
Ding H; Lv Q; Wu S; Hou S; Liu Z; Landen NX; Tian P; Yu M; Sun Z; Fan H
Article: BRITISH JOURNAL OF DERMATOLOGY. 2017;176(3):723-731
Ubiquitin-specific peptidase 2 as a potential link between microRNA-125b and psoriasis
Wei T; Folkersen L; Biskup E; Xu N; Manfe V; Niazi O; Gniadecki R
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2017;139(2):550-561
MicroRNA-146a suppresses IL-17-mediated skin inflammation and is genetically associated with psoriasis
Srivastava A; Nikamo P; Lohcharoenkal W; Li D; Meisgen F; Landen NX; Stahle M; Pivarcsi A; Sonkoly E
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2016;136(12):2485-2494
MicroRNA-203 Inversely Correlates with Differentiation Grade, Targets c-MYC, and Functions as a Tumor Suppressor in cSCC
Lohcharoenkal W; Harada M; Loven J; Meisgen F; Landen NX; Zhang L; Lapins J; Das Mahapatra K; Shi H; Nissinen L; Kahari V-M; Stahle M; Sonkoly E; Grander D; Arsenian-Henriksson M; Pivarcsi A
Article: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2016;19(12):pyw069
MicroRNA 101b Is Downregulated in the Prefrontal Cortex of a Genetic Model of Depression and Targets the Glutamate Transporter SLC1A1 (EAAT3) in Vitro
Bin Wei Y; Melas PA; Villaescusa JC; Liu JJ; Xu N; Christiansen SH; Elbrond-Bek H; Woldbye DPD; Wegener G; Mathe AA; Lavebratt C
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2016;136(3):640-648
Psoriasis Skin Inflammation-Induced microRNA-26b Targets NCEH1 in Underlying Subcutaneous Adipose Tissue
Cheung L; Fisher RM; Kuzmina N; Li D; Li X; Werngren O; Blomqvist L; Stahle M; Landen NX
Article: SCIENTIFIC REPORTS. 2015;5:12017
Circulating levels of sphingosine-1-phosphate are elevated in severe, but not mild psoriasis and are unresponsive to anti-TNF-α treatment
Checa A; Xu N; Sar DG; Haeggstrom JZ; Stahle M; Wheelock CE
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2015;135(6):1676-1685
MicroRNA-31 Promotes Skin Wound Healing by Enhancing Keratinocyte Proliferation and Migration
Li D; Li X; Wang A; Meisgen F; Pivarcsi A; Sonkoly E; Stahle M; Landen NX
Article: BMC MEDICAL GENOMICS. 2015;8:12
Effects of statin on circulating microRNAome and predicted function regulatory network in patients with unstable anginad
Li J; Chen H; Ren J; Song J; Zhang F; Zhang J; Lee C; Li S; Geng Q; Cao C; Xu N
Article: JOURNAL OF PROTEOME RESEARCH. 2015;14(1):557-566
LC-MS Metabolomics of Psoriasis Patients Reveals Disease Severity-Dependent Increases in Circulating Amino Acids That Are Ameliorated by Anti-TNFα Treatment
Kamleh MA; Snowden SG; Grapov D; Blackburn GJ; Watson DG; Xu N; Stahle M; Wheelock CE
Article: ATHEROSCLEROSIS. 2014;237(2):514-520
MicroRNA-223 inhibits tissue factor expression in vascular endothelial cells
Li S; Chen H; Ren J; Geng Q; Song J; Lee C; Cao C; Zhang J; Xu N
Article: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY. 2014;75:49-57
MicroRNA-19b functions as potential anti-thrombotic protector in patients with unstable angina by targeting tissue factor
Li S; Ren J; Xu N; Zhang J; Geng Q; Cao C; Lee C; Song J; Li J; Chen H
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2014;134(7):1931-1940
MiR-146a Negatively Regulates TLR2-Induced Inflammatory Responses in Keratinocytes
Meisgen F; Landen NX; Wang A; Rethi B; Bouez C; Zuccolo M; Gueniche A; Stahle M; Sonkoly E; Breton L; Pivarcsi A
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2014;134(6):1535-1541
Genetic Variants of the IL22 Promoter Associate to Onset of Psoriasis before Puberty and Increased IL-22 Production in T Cells
Nikamo P; Cheuk S; Lysell J; Enerback C; Bergh K; Landen NX; Eidsmo L; Stahle M
Article: CARCINOGENESIS. 2014;35(5):1110-1120
miR-193b/365a cluster controls progression of epidermal squamous cell carcinoma
Gastaldi C; Bertero T; Xu N; Bourget-Ponzio I; Lebrigand K; Fourre S; Popa A; Cardot-Leccia N; Meneguzzi G; Sonkoly E; Pivarcsi A; Mari B; Barbry P; Ponzio G; Rezzonico R
Article: EXPERIMENTAL DERMATOLOGY. 2014;23(4):281-283
Activation of Toll-like receptors alters the microRNA expression profile of keratinocytes
Meisgen F; Landen NX; Bouez C; Zuccolo M; Gueniche A; Stahle M; Sonkoly E; Breton L; Pivarcsi A
Article: PLOS ONE. 2014;9(7):e103206
MicroRNA-31 Is Overexpressed in Cutaneous Squamous Cell Carcinoma and Regulates Cell Motility and Colony Formation Ability of Tumor Cells
Wang A; Landen NX; Meisgen F; Lohcharoenkal W; Stahle M; Sonkoly E; Pivarcsi A
Article: PLOS ONE. 2014;9(1):e87826
Therapeutic Effect of Intravenous Infusion of Perfluorocarbon Emulsion on LPS-Induced Acute Lung Injury in Rats
Hou S; Ding H; Lv Q; Yin X; Song J; Landen NX; Fan H
Article: BRITISH JOURNAL OF DERMATOLOGY. 2013;169(3):563-570
Changes in the level of serum microRNAs in patients with psoriasis after antitumour necrosis factor- therapy
Pivarcsi A; Meisgen F; Xu N; Stahle M; Sonkoly E
Article: JOURNAL OF IMMUNOLOGY. 2013;190(2):678-688
MicroRNA-31 Is Overexpressed in Psoriasis and Modulates Inflammatory Cytokine and Chemokine Production in Keratinocytes via Targeting Serine/Threonine Kinase 40
Xu N; Meisgen F; Butler LM; Han G; Wang X-J; Soderberg-Naucler C; Stahle M; Pivarcsi A; Sonkoly E
Article: PLOS ONE. 2013;8(12):e80738
Signature of Circulating MicroRNAs as Potential Biomarkers in Vulnerable Coronary Artery Disease
Ren J; Zhang J; Xu N; Han G; Geng Q; Song J; Li S; Zhao J; Chen H
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2012;287(35):29899-29908
MicroRNA-125b Down-regulates Matrix Metallopeptidase 13 and Inhibits Cutaneous Squamous Cell Carcinoma Cell Proliferation, Migration, and Invasion
Xu N; Zhang L; Meisgen F; Harada M; Heilborn J; Homey B; Grander D; Stahle M; Sonkoly E; Pivarcsi A
Article: EXPERIMENTAL DERMATOLOGY. 2012;21(4):312-314
MiR-21 is uip-regulated n psoriasis and suppresses T cell apoptosis
Meisgen F; Xu N; Wei T; Janson PC; Obad S; Broom O; Nagy N; Kauppinen S; Kemeny L; Stahle M; Pivarcsi A; Sonkoly E
Article: ONCOGENESIS. 2012;1(3):e3
MicroRNA-203 functions as a tumor suppressor in basal cell carcinoma
Sonkoly E; Loven J; Xu N; Meisgen F; Wei T; Brodin P; Jaks V; Kasper M; Shimokawa T; Harada M; Heilborn J; Hedblad M-A; Hippe A; Grander D; Homey B; Zaphiropoulos PG; Arsenian-Henriksson M; Stahle M; Pivarcsi A
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2011;131(7):1521-1529
MiR-125b, a MicroRNA Downregulated in Psoriasis, Modulates Keratinocyte Proliferation by Targeting FGFR2
Xu N; Brodin P; Wei T; Meisgen F; Eidsmo L; Nagy N; Kemeny L; Stahle M; Sonkoly E; Pivarcsi A
Article: METHODS IN MOLECULAR BIOLOGY. 2011;721:183-198
Characterization of RISC-associated adenoviral small RNAs.
Xu N; Akusjärvi G
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2010;126(3):581-9.e1-20-U306
MiR-155 is overexpressed in patients with atopic dermatitis and modulates T-cell proliferative responses by targeting cytotoxic T lymphocyte-associated antigen 4
Sonkoly E; Janson P; Majuri M-L; Savinko T; Fyhrquist N; Eidsmo L; Xu N; Meisgen F; Wei T; Bradley M; Stenvang J; Kauppinen S; Alenius H; Lauerma A; Homey B; Winqvist O; Stahle M; Pivarcsi A
Article: NUCLEIC ACIDS RESEARCH. 2009;37(20):6950-6959
The 5'-end heterogeneity of adenovirus virus-associated RNAI contributes to the asymmetric guide strand incorporation into the RNA-induced silencing complex
Xu N; Gkountela S; Saeed K; Akusjarvi G
Article: JOURNAL OF VIROLOGY. 2007;81(19):10540-10549
Adenovirus virus-associated RNAII-Derived small RNAs are efficiently incorporated into the RNA-Induced silencing complex and associate with polyribosomes
Xu N; Segerman B; Zhou X; Akusjarvi G
Article: METHODS IN MOLECULAR MEDICINE. 2007;131:47-61
In vitro methods to study RNA interference during an adenovirus infection.
Andersson G; Xu N; Akusjärvi G
Article: JOURNAL OF VIROLOGY. 2005;79(15):9556-9565
Suppression of RNA interference by adenovirus virus-associated RNA
Andersson MG; Haasnoot PCJ; Xu N; Berenjian S; Berkhout B; Akusjärvi G
Visa fler

Alla övriga publikationer

Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2024;144(12):s321
538 Spatiotemporal Single-Cell Roadmap of Human Skin Wound Healing
Liu Z; Li D; Landén NX
Preprint: BIORXIV. 2024
Spatiotemporal Single-Cell Roadmap of Human Skin Wound Healing
Liu Z; Li D; Bian X; Luo L; Björklund ÅK; Li L; Zhang L; Chen Y; Guo L; Gao J; Cao C; Wang J; He W; Xiao Y; Zhu L; Annusver K; Gopee H; Bennett CL; Kasper M; Haniffa M; Sommar P; Landén NX
Preprint: BIORXIV. 2024
Circular RNA circASH1L(4,5) protects microRNA-129-5p from target-directed microRNA degradation in human skin wound healing
Wang Q; Niu G; Liu Z; Toma MA; Geara J; Bian X; Zhang L; Piipponen M; Li D; Sommar P; Landén NX
Review: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2023;143(9):1667-1677
A Roadmap for a Consensus Human Skin Cell Atlas and Single-Cell Data Standardization
Almet AA; Yuan H; Annusver K; Ramos R; Liu Y; Wiedemann J; Sorkin DH; Landen NX; Sonkoly E; Haniffa M; Nie Q; Lichtenberger BM; Luecken MD; Andersen B; Tsoi LC; Watt FM; Gudjonsson JE; Plikus MV; Kasper M
Preprint: RESEARCH SQUARE. 2023
Epigenetic memory of radiotherapy in dermal fibroblasts impairs wound repair capacity in cancer survivors
Landén NX; Piipponen M; Bian X; Liu Z; Sangsuwan T; Maselli M; Diaz C; Luo L; Archambault L; Haghdoost S; Fradette J; Sommar P; Halle M
Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2023;143(5):s251
1465 Circular RNA circASH1L protects miRNA-129-5p from target-directed miRNA degradation in human skin wound healing
Wang Q; Landén NX
Thesis / dissertation: 2023
Understanding the role of regulatory RNAs in human skin wound healing
Zhang, Letian
Preprint: BIORXIV. 2022
The injury-induced circular RNA circGLIS3 activates dermal fibroblasts to promote wound healing
Toma MA; Wang Q; Li D; Xiao Y; Niu G; Geara J; Vij M; Piipponen M; Liu Z; Zhang L; Bian X; Wang A; Sommar P; Landén NX
Preprint: RESEARCH SQUARE. 2022
Human skin specific long noncoding RNA HOXC13-AS regulates epidermal differentiation by interfering with Golgi-ER retrograde transport
Zhang L; Piipponen M; Liu Z; Li D; Bian X; Toma M; Sommar P; Landén NX
Preprint: BIORXIV. 2022
Human skin specific long noncoding RNA HOXC13-AS regulates epidermal differentiation by interfering with Golgi-ER retrograde transport
Zhang L; Piipponen M; Liu Z; Li D; Bian X; Toma M; Sommar P; Xu Landén N
Thesis / dissertation: 2022
Regulatory roles for long noncoding RNAs and circular RNAs in human skin wound repair
Toma, Maria-Alexandra
Preprint: BIORXIV. 2021
Integrative small and long RNA-omics analysis of human healing and non-healing wounds discovers cooperating microRNAs as therapeutic targets
Liu Z; Zhang L; Toma M; Li D; Bian X; Pastar I; Tomic-Canic M; Sommar P; Landén NX
Review: HEALTH SCIENCE REPORTS. 2021;4(4):e374
Targeting microRNA for improved skin health
Li X; Ponandai-Srinivasan S; Nandakumar KS; Fabre S; Landen NX; Mavon A; Khmaladze I
Preprint: BIORXIV. 2021
Circular RNA signatures of human healing and non-healing wounds
Toma M; Liu Z; Wang Q; Zhang L; Li D; Sommar P; Landén NX
Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2021;141(10):S209
Identification of a novel skin-specific long non-coding RNA regulating keratinocyte differentiation
Zhang L; Piipponen MM; Landen NX
Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2021;141(10):S210
The circular RNA circGLIS3 activates dermal fibroblasts and increases ECM production to improve wound healing
Toma MA; Wang Q; Vij M; Liu Z; Piipponen MM; Bian X; Li D; Wang A; Sommar P; Landen NX
Conference publication: WOUND REPAIR AND REGENERATION. 2021;29(3):A16-A17
Single-cell Transcriptomics Of Human Pressure Ulcers Reveals Mhcii Expressing Keratinocytes In Patients With A Worse Healing Outcome
Landen NX; Li D; Cheng S; Deng Q; Sommar P; Pei Y; Karner J; Herter E; Toma M; Zhang L; Pham K; Chen X; Eidsmo L
Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2021;141(5):S111
Single-cell transcriptomics of human pressure ulcers reveals MHCII expressing keratinocytes in patients with a worse healing outcome
Li D; Cheng S; Deng Q; Landen NX
Review: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2020;21(22):E8790-8790
The Immune Functions of Keratinocytes in Skin Wound Healing
Piipponen M; Li D; Landen NX
Letter: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2019;139(12):2547-2550.e12
Next-Generation Sequencing Identifies the Keratinocyte-Specific miRNA Signature of Psoriasis
Srivastava A; Meisgen F; Pasquali L; Munkhammar S; Xia P; Stahle M; Landen NX; Pivarcsi A; Sonkoly E
Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2019;139(9):S323
Human skin long noncoding RNA WAKMAR1 regulates wound healing by enhancing keratinocyte migration
Li D; Kular L; Vij M; Li X; Wang A; Toma M; Zhang L; Blomqvist L; Serezal I; Bienko M; Berglund D; Stahle M; Sommar P; Jagodic M; Landen NX
Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2019;139(9):S277
MiR-1307 is upregulated in psoriasis keratinocytes and promotes keratinocyte inflammatory response
Srivastava A; Meisgen F; Pasquali L; Munkhammar S; Xia P; Stahle M; Landen NX; Pivarcsi A; Sonkoly E
Thesis / dissertation: 2019
The roles of microRNAs in skin wound healing
Li, Xi
Conference publication: WOUND REPAIR AND REGENERATION. 2019;27(3):A37
HUMAN SKIN LONG NON-CODING RNA WAKMAR1 REGULATES WOUND HEALING BY ENHANCING KERATINOCYTE MIGRATION
Li D; Kular L; Vij M; Herter EK; Li X; Wang A; Chu T; Toma M-A; Zhang L; Liapi E; Blomqvist L; Serezal IG; Rollman O; Wikstrom JD; Berglund D; Stahle M; Sommar P; Jagodic M; Landen NX
Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2018;138(5):S246
The role of microRNA-34 in skin wound healing
Wu J; Li X; Li D; Herter E; Qian M; Wikstrom J; Ye X; Landen NX
Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2018;138(5):S67
Next-generation sequencing identifies epidermal miRNAs deregulated in psoriasis skin
Srivastava A; Meisgen F; Pasquali L; Stahle M; Landen NX; Pivarcsi A; Sonkoly E
Conference publication: EXPERIMENTAL DERMATOLOGY. 2018;27:27
Next generation sequencing identifies the keratinocyte-specific miRNA signature of psoriasis
Srivastava A; Meisgen F; Pasquali L; Munkhammar S; Xia P; Stahle M; Landen NX; Pivarcsi A; Sonkoly E
Conference publication: EXPERIMENTAL DERMATOLOGY. 2018;27:19-20
The keratinocyte transcriptome in psoriasis: pathways related to immune responses, cell cycle and keratinization
Pasquali L; Srivastava A; Meisgen F; Mahapatra KD; Xia P; Landen NX; Pivarcsi A; Sonkoly E
Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2017;137(10):s306
660 Comparison of microRNAome of human normal and chronic wounds reveals microRNA-17∼92 is critical for wound repair
Li D; Wikstrom J; Herter E; Li X; Pivarcsi A; Sonkoly E; Ståhle M; Mi Q; Zhou L; Landén NX
Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2017;137(10):S253
Identification of the epidermal miRNome in psoriasis skin
Srivastava A; Pasquali L; Meisgen F; Stahle MM; Landen NX; Pivarcsi A; Sonkoly E
Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2017;137(10):S283
MicroRNA-130a (miR-130a) regulates self-renewal capacity and tumor growth in cutaneous squamous cell carcinoma
Lohcharoenkal W; Das Mahapatra K; Landen NX; Sonkoly E; Pivarcsi A
Review: EUROPEAN JOURNAL OF DERMATOLOGY. 2017;27(S1):12-14
MicroRNAs in skin wound healing
Li D; Landen NX
Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2017;137(5):S161
MicroRNA-132 with therapeutic potential in chronic wound
Li X; Li D; Wang A; Chu T; Lohcharoenkal W; Herter E; Ehrstrom M; Eidsmo L; Pivarcsi A; Sonkoly E; Catrina S; Stahle M; Landen NX
Review: ADVANCES IN WOUND CARE. 2017;6(3):93-107
Non-Coding RNAs: New Players in Skin Wound Healing
Herter EK; Landen NX
Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2017;137(10):S306
Comparison of microRNAome of human normal and chronic wounds reveals microRNA-17 ∼92 is critical for wound repair
Li D; Wikstrom J; Herter E; Li X; Pivarcsi A; Sonkoly E; Stahle M; Mi Q; Zhou L; Landen NX
Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2017;137(10):S306
Long non-coding RNA WANCR1 regulates skin wound healing by enhancing keratinocytes migration
Li D; Herter E; Li X; Wang A; Wikstrom J; Sonkoly E; Pivarcsi A; Stahle M; Landen NX
Conference publication: BRITISH JOURNAL OF DERMATOLOGY. 2017;177(5):E253
Next-generation sequencing identifies epidermal microRNAs deregulated in psoriasis skin
Srivastava A; Pasquali L; Meisgen F; Stahle M; Landen NX; Pivarcsi A; Sonkoly E
Conference publication: BRITISH JOURNAL OF DERMATOLOGY. 2017;177(5):E243
Activation of resident T cells in resolved psoriasis reveals tissue responses that stratify clinical outcome
Serezal IG; Classon C; Nylen S; Landen NX; Martini E; Cheuk S; Eidsmo L
Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2016;136(9):S256
MicroRNA-132, a promising target for wound therapy
Li X; Li D; Wang A; Lohcharoenkal W; Gruenler J; Narayanan S; Sonkoly E; Pivarcsi A; Sergiu-Bogdan C; Stahle M; Landen NX
Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2016;136(9):S226
MicroRNA-146a suppresses IL-17-mediated skin inflammation and is genetically associated with psoriasis
Srivastava A; Nikamo P; Lohcharoenkal W; Li D; Meisgen F; Landen N; Stahle MM; Pivarcsi A; Sonkoly E
Meeting abstract: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2016;136(9):S254
MicroRNA-17-92 promotes wound healing by regulating inflammatory response in keratinocytes
Li D; Li X; Herter E; Wang A; Pivarcsi A; Sonkoly E; Stahle MM; Landen N
Conference publication: CANCER RESEARCH. 2016;76:1098
MiR-203 suppresses cutaneous squamous cell carcinoma growth and targets the myc oncogene
Lohcharoenkal W; Harada M; Loven J; Meisgen F; Landen NX; Zhang L; Nissinen L; Kahari V-M; Stahle M; Sonkoly E; Grander D; Arsenian-Henriksson M; Pivarcsi A
Conference publication: MELANOMA RESEARCH. 2016;26:E116
MicroRNA-203 inversely correlates with differentiation grade and suppresses cutaneous squamous cell carcinoma growth via targeting c-myc oncogene
Lohcharoenkal W; Harada M; Loven J; Meisgen F; Landen NX; Zhang L; Lapins J; Das Mahapatra K; Shi H; Nissinen L; Kahari V-M; Stahle M; Sonkoly E; Grander D; Arsenian-Henriksson M; Pivarcsi A
Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2016;136(9):S245
MicroRNA-203 inhibits SLUG and suppresses melanoma cell motility, tumor growth and lung-metastasis
Lohcharoenkal W; Das Mahapatra K; Zhang L; Landen N; Girnita L; Stahle MM; Sonkoly E; Pivarcsi A
Review: IUBMB LIFE. 2015;67(8):601-610
New insights into T cells and their signature cytokines in atopic dermatitis
Wang A-X; Landen NX
Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2015;135:S20
Anti-tumor effect of an epithelial microRNA, miR-203, in melanoma
Lohcharoenkal W; Zhang L; Landen NX; Stahle M; Girnita L; Sonkoly E; Pivarcsi A
Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2015;135:S4
Psoriasis skin inflammation modulates microRNA expression of subcutaneous adipose tissue - a missing link between psoriasis and co-morbidities?
Cheung L; Fisher R; Kuzmina N; Li D; Li X; Werngren O; Blomqvist L; Stahle M; Landen NX
Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2015;135:S18
MiR-203 is suppressed in poorly but not well-differentiated cutaneous squamous cell carcinomas and regulates the expression of MYC oncogene
Lohcharoenkal W; Harada M; Loven J; Landen NX; Stahle M; Sonkoly E; Arsenian-Henriksson M; Grander D; Pivarcsi A
Conference publication: EXPERIMENTAL DERMATOLOGY. 2015;24(12):986
MiR-146a, a MicroRNA overexpressed in psoriasis, is a potent regulator of inflammatory responses in keratinocytes
Srivastava A; Lohcharoenkal W; Li D; Meisgen F; Landen NX; Stahle M; Pivarcsi A; Sonkoly E
Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2015;135:S24
MiR-146a, a microRNA overexpressed in psoriasis, is a potent regulator of IL-1β - induced inflammatory responses in keratinocytes
Meisgen F; Srivastava A; Landen NX; Stahle M; Pivarcsi A; Sonkoly E
Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2015;135:S74
MicroRNA-146a is up-regulated in psoriasis keratinocytes and is induced by IL-36α
Srivastava A; Meisgen F; Landen NX; Stahle M; Pivarcsi A; Sonkoly E
Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2015;135:S64
MicroRNA-132 supports wound healing by enhancing inflammatory-proliferative phase transition
Li D; Wang A; Meisgen F; Grunler J; Catrina S; Stahle M; Landen NX
Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2015;135:S6
MiR-146a, a microRNA overexpressed in psoriasis, regulates IL1β-induced production of inflammatory mediators in keratinocytes
Meisgen F; Srivastava A; Landen NX; Stahle M; Pivarcsi A; Sonkoly E
Conference publication: BRITISH JOURNAL OF DERMATOLOGY. 2014;171(6):E155
miR-146a, a microRNA overexpressed in psoriasis, is a potent regulator of interleukin-1β-induced inflammatory responses in keratinocytes
Meisgen F; Landen NX; Stahle M; Pivarcsi A; Sonkoly E
Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2014;134:S77
Activation of Toll-like receptors alters microRNA expression in keratinocytes
Meisgen F; Landen NX; Bouez C; Zuccolo M; Gueniche A; Stahle M; Sonkoly E; Breton L; Pivarcsi A
Letter: ACTA DERMATO-VENEREOLOGICA. 2013;93(3):366-367
Are BIC (miR-155) Polymorphisms Associated with Eczema Susceptibility?
Saaf A; Kockum I; Wahlgren C-F; Xu N; Sonkoly E; Stahle M; Nordenskjold M; Bradley M; Pivarcsi A
Published conference paper: EUROPEAN JOURNAL OF DERMATOLOGY. 2013;23:66-71
Interleukin-8 is regulated by miR-203 at the posttranscriptional level in primary human keratinocytes
Wei T; Xu N; Meisgen F; Stahle M; Sonkoly E; Pivarcsi A
Review: YI CHUAN = HEREDITAS / ZHONGGUO YI CHUAN XUE HUI BIAN JI.. 2012;34(6):784-792
[Application of next generation sequencing in microRNA detection].
Tang H-M; Chen H; Zhang J; Ren J-Y; Xu N
Letter: EXPERIMENTAL DERMATOLOGY. 2010;19(9):854-856
The expression of microRNA-203 during human skin morphogenesis
Wei T; Orfanidis K; Xu N; Janson P; Stahle M; Pivarcsi A; Sonkoly E
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Lektor, Medicin, Solna, Karolinska Institutet, 2022-

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Docent, Experimentell dermatologi och venereologi, Karolinska Institutet, 2017
PhD, Institutionen för medicinsk biokemi och mikrobiologi, Uppsala University, 2008

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