Melody Chemaly

Publikationer
Populärvetenskap och samverkan

Artiklar

Journal article: ATHEROSCLEROSIS. 2024;395:117757

Multi-omics integration from a large human biobank identifies key molecular mechanisms and signatures of atherosclerotic plaque instability

Das V; Zhang X; Djordjevic D; Bergman O; Narayanan S; Shungin D; Chemaly M; Karadimou G; Vuckovic S; Prasad I; Knape KC; Michaelsen NB; Hedin U; Matic L
Journal article: CARDIOVASCULAR RESEARCH. 2024;120(8):811-813

NOT lost in translation: translatome mapping as a novel approach to identify regulators of atherosclerosis

Matic L; Chemaly M; Jorgensen HF
Journal article: CARDIOVASCULAR RESEARCH. 2024;120:cvae088.208

The novel bispecific anti-NLRP3 inflammasome antibody InflamAb inhibits atherosclerosis in apolipoprotein E-deficient mice

Delfos L; Depuydt MAC; Kleijn MNAB; Foks AC; Kuiper J; Chemaly M; Peace A; Mcgilligan V; Bot I
Journal article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2024;44(Suppl_1)

Abstract 143: Multi-omics Integration From A Large Human Biobank Identifies Key Molecular Mechanisms And Signatures Of Atherosclerotic Plaque Instability

Das V; Zhang X; Djordjevic D; Bergman O; Narayanan S; Shungin D; Chemaly M; Karadimou G; Vuckovic S; Prasad I; Conde Knape K; Barascuk Michaelsen1 N; Hedin U; Matic L
Journal article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2024;44(Suppl_1)

Abstract 1155: Symptomatic Low- And High-degree Carotid Stenoses Exhibit Similar Features Of Plaque Instability

Shlemoun P; Hellberg S; Waden K; Bergman O; Lengquist M; Buckler AJ; Matic L; Chemaly M; Marlevi D; Hedin U
Journal article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2024;44(Suppl_1)

Abstract 131: Local Pcsk6 Inhibition Attenuates VSMC Response In Vascular Injury And Restenosis

Chemaly M; Jin H; Vuckovic S; Suur BE; Zhang X; Kronqvist M; Lengquist M; Uryga A; Knape KC; Nyberg M; Hedin U; Matic L; Matic L
Journal article: ATHEROSCLEROSIS. 2023;379:s180

BILIVERDIN REDUCTASE B IS A PLASMA BIOMARKER FOR INTRAPLAQUE HEMORRHAGE AND A PREDICTOR OF ISCHEMIC STROKE IN SYMPTOMATIC CAROTID STENOSIS

Chemaly M; Marlevi D; Iglesias M-J; Lengquist M; Kronqvist M; Bos D; Van Dam-Nolen DHK; Van Der Kolk A; Hendrikse J; Kassem M; Matic L; Odeberg J; De Vries MR; Kooi ME; Hedin U
Journal article: ATHEROSCLEROSIS. 2023;379:s2

NLRP3 INFLAMMASOME INHIBITION BY THE NOVEL BISPECIFIC ANTIBODY INFLAMAB INHIBITS ATHEROSCLEROSIS IN APOLIPOPROTEIN E-DEFICIENT MICE

Delfos L; Depuydt MAC; Foks A; Kleijn MB; Kuiper J; Chemaly M; Peace A; Mcgilligan V; Bot I
Article: BIOMOLECULES. 2023;13(6):882

Biliverdin Reductase B Is a Plasma Biomarker for Intraplaque Hemorrhage and a Predictor of Ischemic Stroke in Patients with Symptomatic Carotid Atherosclerosis

Chemaly M; Marlevi D; Iglesias M-J; Lengquist M; Kronqvist M; Bos D; van Dam-Nolen DHK; van der Kolk A; Hendrikse J; Kassem M; Matic L; Odeberg J; de Vries MR; Kooi ME; Hedin U
Journal article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2023;43

Biliverdin Reductase B Is A Plasma Biomarker For Intraplaque Hemorrhage And A Predictor Of Ischemic Stroke In Symptomatic Carotid Stenosis

Chemaly M; Marlevi D; Mareque MJI; Lengquist M; Kronqvist M; Bos D; van Dam-Nolen DHK; van der Kolk A; Hendrikse J; Kassem M; Matic L; Odeberg J; De Vries MR; Kooi ME; Hedin U
Journal article: JVS - VASCULAR SCIENCE. 2023;4:100142

Biliverdin Reductase B Is a Plasma Biomarker for Intraplaque Hemorrhage and a Predictor of Ischemic Stroke in Symptomatic Carotid Stenosis

Chemaly M; Marlevi D; Mareque MJI; Lengquist M; Kronqvist M; Bos D; van Dam-Nolen DHK; van der Kolk A; Hendrikse J; Kassem M; Matic L; Odeberg J; De Vries MR; Kooi ME; Hedin U
Article: ATHEROSCLEROSIS PLUS. 2022;50:40-49

TACE/ADAM17 substrates associate with ACS (Ep-CAM, HB-EGF) and follow-up MACE (TNFR1 and TNFR2)

Chemaly M; McAllister R; Peace A; Bjourson AJ; Watterson S; Parton A; Clauss M; McGilligan V
Journal article: ATHEROSCLEROSIS. 2022;355:24

Novel roles of PCSK6 in adipose tissue homeostasis

Chemaly M; Suur B; Schipper R; Jin H; Hagberg C; Matic LP
Journal article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2022;42:a419

Therapeutic Potential Of The Proprotein Convertase Subtilisin/Kexin ( PCSK) Family In Vascular Disease

Suur BE; Chemaly M; Liljeqvist ML; Djordjevic D; Stenemo M; Bergman O; Karlof E; Lengquist M; Odeberg J
Journal article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2022;42:a420

Proprotein Convertase Subtilisin/Kexin 6 Is Involved In Lipid Metabolism In Liver

Suur B; Chemaly M; Karadimou G; Jin H; Kronqvist M; Lengquist M; van der Laan SW; Lleal MS; Malarstig A
Journal article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2022;42:a105

Proprotein Convertase Subtilisin/kexin Type 6 (Pcsk6) Plays A Role In Angiogenesis Regulation

Chemaly M; Dong X; Suur BE; Jin H; Malarstig A; Matic L
Article: FRONTIERS IN PHARMACOLOGY. 2022;13:988561

Therapeutic potential of the Proprotein Convertase Subtilisin/Kexin family in vascular disease

Suur BE; Chemaly M; Liljeqvist ML; Djordjevic D; Stenemo M; Bergman O; Karlof E; Lengquist M; Odeberg J; Hurt-Camejo E; Eriksson P; Ketelhuth DFJ; Roy J; Hedin U; Nyberg M; Matic L
Journal article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2021;41

Proprotein Convertase Subtilisin/kexin Type 6 (PCSK6) Is Involved In Regulation Of Vasculogenesis

Chemaly M; Suur BE; Jin H; Malarstig A; Matic L
Journal article: JOURNAL OF ELECTROCARDIOLOGY. 2019;57:S92-S97

An exploratory analysis investigating blood protein biomarkers to augment ECG diagnosis of ACS

McGilligan V; Watterson S; Rjoob K; Chemaly M; Bond R; Iftikhar A; Knoery C; Leslie SJ; McShane A; Bjourson A; Peace A
Journal article: BIOINFORMATICS. 2019;35(14):2449-2457

New models of atherosclerosis and multi-drug therapeutic interventions

Parton A; McGilligan V; Chemaly M; O'Kane M; Watterson S
Journal article: MEDIATORS OF INFLAMMATION. 2019;2019:2363460-11

Exploring the Involvement of NLRP3 and IL-1β in Osteoarthritis of the Hand: Results from a Pilot Study

Fioravanti A; Tenti S; McAllister M; Chemaly M; Eakin A; McLaughlin J; Bjourson AJ; Frati E; McGilligan V; Cheleschi S; Gibson DS
Journal article: OSTEOARTHRITIS AND CARTILAGE. 2018;26(5):612-619

NLRP3 as a potentially novel biomarker for the management of osteoarthritis

McAllister MJ; Chemaly M; Eakin AJ; Gibson DS; McGilligan VE
Journal article: ARCHIVES OF CARDIOVASCULAR DISEASES. 2017;110(12):700-711

Role of tumour necrosis factor alpha converting enzyme (TACE/ADAM17) and associated proteins in coronary artery disease and cardiac events

Chemaly M; McGilligan V; Gibson M; Clauss M; Watterson S; Alexander HD; Bjourson AJ; Peace A
Journal article: EUROPEAN HEART JOURNAL. 2017;38(suppl_1):ehx493.p6229

P6229TACE gene expression and soluble receptors TNFRI and TNFRII levels identifies very high risk cardiovascular patients

Chemaly M; Gibson M; Watterson S; Bjourson T; McGilligan V; Peace A
Journal article: CURRENT ATHEROSCLEROSIS REPORTS. 2014;16(9):439

Living the PCSK9 Adventure: from the Identification of a New Gene in Familial Hypercholesterolemia Towards a Potential New Class of Anticholesterol Drugs

Abifadel M; Elbitar S; El Khoury P; Ghaleb Y; Chemaly M; Moussalli M-L; Rabes J-P; Varret M; Boileau C
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Preprint: PREPRINTS.ORG. 2024

Senescence Biomarkers CKAP4 and PTX3 Stratify Severe Kidney Disease Patients

McCallion S; McLarnon T; Cooper E; English A; Watterson S; Chemaly M; McGeough CM; Eakin A; Ahmed T; Gardiner P; Pendleton A; Wright G; McGuigan D; O'Kane M; Peace A; Kuan Y; Gibson DS; McClean PL; Kelly C; McGilligan VE; Murray EK; McCarroll F; Bjourson AJ; Rai TS
Preprint: BIORXIV. 2024;BIORXIV

Multiomics unveils extracellular vesicle-driven mechanisms of endothelial communication in human carotid atherosclerosis.

Raju S; Turner ME; Cao C; Abdul-Samad M; Punwasi N; Blaser MC; Cahalane RM; Botts SR; Prajapati K; Patel S; Wu R; Gustafson D; Galant NJ; Fiddes L; Chemaly M; Hedin U; Matic L; Seidman M; Subasri V; Singh SA; Aikawa E; Fish JE; Howe KL
Editorial comment: ATHEROSCLEROSIS. 2023;387:117365

The more the merrier: Severe vascular injury increases engagement of smooth muscle cell clones in intimal repair

Hedin U; Chemaly M; Matic L
Editorial comment: CARDIOVASCULAR RESEARCH. 2023;119(5):1100-1102

Smooth muscle cell oligoclonality in vascular disease: same origin, different destinies

Matic L; Chemaly M; Hedin U
Conference publication: BRITISH JOURNAL OF PHARMACOLOGY. 2023;180:790-791

NLRP3 Inflammasome associated proteins are predictive of COVID19 patient hospitalisation

Donnelly S; Bond R; Peace A; Rai TS; Lynch S; McDaid D; McLaughlin J; English A; Walsh C; Shulka P; Murray E; Zhang S-D; Chemaly M; O'Kane M; Kelly M; Bhavsar M; Gibson D; Bjourson T; McGilligan V
Conference publication: DIABETOLOGIA. 2023;66(SUPPL 1):S129-S130

Application of multiomics to identify novel molecular mechanisms of atherosclerotic plaque instability in type 2 diabetes patients

Das V; Zhang X; Djordjevic D; Bergman O; Chemaly M; Shungin D; Michaelsen N; Knape K; Hedin U; Matic L
Conference publication: ATHEROSCLEROSIS. 2022;355:E54-E55

NOVEL ROLES OF PCSK6 IN ADIPOSE TISSUE HOMEOSTASIS

Chemaly M; Suur B; Schipper R; Jin H; Hagberg C; Matic LP
Review: BIOMOLECULES. 2021;11(8):1239

Targeting the NLRP3 Inflammasome in Glaucoma

Coyle S; Khan MN; Chemaly M; Callaghan B; Doyle C; Willoughby CE; Atkinson SD; Gregory-Ksander M; McGilligan V
Conference publication: ATHEROSCLEROSIS. 2021;331:E4

PROPROTEIN CONVERTASE SUBTILISIN/KEXIN 6 IS INVOLVED IN LIPID METABOLISM IN LIVER AND ADIPOSE TISSUE

Suur BE; Chemaly M; Jin H; Kronqvist M; Lengquist M; Van der Laan SW; Lleal MS; Malarstig A; Pasterkamp G; Eriksson P; Hedin U; Ketelhuth DFJ; Hurt-Camejo E; Matic L
Conference publication: HEART. 2020;106(Suppl 1):a8

P8 A freely available, simple-to-use, computational model of atherosclerosis

Watterson S; Parton A; McGilligan V; Chemaly M; O’Kane M
Conference publication: COMPUTING IN CARDIOLOGY. 2020;00:1-4

Improving the Detection of Acute Coronary Syndrome Using Machine Learning of Blood Biomarkers

Rjoob K; McGilligan V; Bond R; Watterson S; Chemaly M; McAlister R; De Melo Malaquias T; Leslie SJ; Knoery C; Iftikhar A; McShane A; Bjourson A; Peace A
Conference publication: HEART. 2017;103(Suppl 6):a31-A32

54 The nlrp3 inflammasome and other related receptors as potential biomarkers in coronary artery disease (cad) and major adverse cardiac events (mace)

Gallagher L; McCusker M; Chemaly M; Peace A; Gibson M; Bjourson A; Kelly C; McGilligan V

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