Marie Meeths

Publikationer
CV
Populärvetenskap och samverkan

Utvalda publikationer

Article: BLOOD. 2024;143(3):233-242

Malignancy-associated hemophagocytic lymphohistiocytosis in Sweden: incidence, clinical characteristics, and survival

Lofstedt A; Jadersten M; Meeths M; Henter J-I
Article: CANCER. 2019;125(11):1848-1854

Haploinsufficiency of UNC13D increases the risk of lymphoma

Lofstedt A; Ahlm C; Tesi B; Bergdahl IA; Nordenskjold M; Bryceson YT; Henter J-I; Meeths M
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2018;142(1):317-321.e8

A RAB27A 5′ untranslated region structural variant associated with late-onset hemophagocytic lympho-histiocytosis and normal pigmentation

Tesi B; Rascon J; Chiang SCC; Burnyte B; Lofstedt A; Fasth A; Heizmann M; Juozapaite S; Kiudeliene R; Kvedaraite E; Miseviciene V; Muleviciene A; Mueller M-L; Nordenskjold M; Matuzeviciene R; Samaitiene R; Speckmann C; Stankeviciene S; Zekas V; Voss M; Ehl S; Vaiciene-Magistris N; Henter J-I; Meeths M; Bryceson YT
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2016;36(5):480-489

Successful Hematopoietic Stem Cell Transplantation in a Patient with LPS-Responsive Beige-Like Anchor (LRBA) Gene Mutation

Tesi B; Priftakis P; Lindgren F; Chiang SCC; Kartalis N; Lofstedt A; Lorinc E; Henter J-I; Winiarski J; Bryceson YT; Meeths M
Article: PEDIATRIC BLOOD & CANCER. 2015;62(12):2094-2100

Spectrum of Atypical Clinical Presentations in Patients With Biallelic PRF1 Missense Mutations

Tesi B; Chiang SCC; El-Ghoneimy D; Hussein AA; Langenskiold C; Wali R; Fadoo Z; Silva JP; Lecumberri R; Unal S; Nordenskjold M; Bryceson YT; Henter J-I; Meeths M
Article: LANCET HAEMATOLOGY. 2015;2(12):e536-e542

Cancer risk in relatives of patients with a primary disorder of lymphocyte cytotoxicity: a retrospective cohort study

Lofstedt A; Chiang SCC; Oneloev E; Bryceson YT; Meeths M; Henter J-I
Article: BLOOD. 2011;118(22):5783-5793

Familial hemophagocytic lymphohistiocytosis type 3 (FHL3) caused by deep intronic mutation and inversion in UNC13D

Meeths M; Chiang SCC; Wood SM; Entesarian M; Schlums H; Bang B; Nordenskjold E; Bjorklund C; Jakovljevic G; Jazbec J; Hasle H; Holmqvist B-M; Rajic L; Pfeifer S; Rosthoj S; Sabel M; Salmi TT; Stokland T; Winiarski J; Ljunggren H-G; Fadeel B; Nordenskjold M; Henter J-I; Bryceson YT
Article: BLOOD. 2010;116(15):2635-2643

Spectrum of clinical presentations in familial hemophagocytic lymphohistiocytosis type 5 patients with mutations in STXBP2

Meeths M; Entesarian M; Al-Herz W; Chiang SCC; Wood SM; Al-Ateeqi W; Almazan F; Boelens JJ; Hasle H; Ifversen M; Lund B; van den Berg JM; Gustafsson B; Hjelmqvist H; Nordenskjold M; Bryceson YT; Henter J-I

Artiklar

Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2022;149(1):388-399.e4

Rubella vaccine-induced granulomas are a novel phenotype with incomplete penetrance of genetic defects in cytotoxicity

Gross M; Speckmann C; May A; Gajardo-Carrasco T; Wustrau K; Maier SL; Panning M; Huzly D; Agaimy A; Bryceson YT; Choo S; Chow CW; Dueckers G; Fasth A; Fraitag S; Graewe K; Haxelmans S; Holzinger D; Hudowenz O; Huebschen JM; Khurana C; Kienle K; Klifa R; Korn K; Kutzner H; Laemmermann T; Ledig S; Lipsker D; Meeths M; Naumann-Bartsch N; Rascon J; Schaenzer A; Seidl M; Tesi B; Vauloup-Fellous C; Vollmer-Kary B; Warnatz K; Wehr C; Neven B; Vargas P; Sepulveda FE; Lehmberg K; Schmitt-Graeff A; Ehl S
Article: JOURNAL OF RHEUMATOLOGY. 2021;48(10):1596-1602

Efficacy of Moderately Dosed Etoposide in Macrophage Activation Syndrome-Hemophagocytic Lymphohistiocytosis

Horne A; Greenwood TVB; Chiang SCC; Meeths M; Bjorklund C; Ekelund M; Erensjo P; Berg S; Hagelberg S; Bryceson YT; Andersson U; Henter J-I
Article: AMERICAN JOURNAL OF MEDICAL GENETICS PART A. 2021;185(2):517-527

Chondrodysplasia and growth failure in children after early hematopoietic stem cell transplantation for non-oncologic disorders

Botto LD; Meeths M; Campos-Xavier B; Bergamaschi R; Mazzanti L; Scarano E; Finocchi A; Cancrini C; Zirn B; Kuehnle I; Kramm CM; Alanay Y; Jones WD; Irving M; Sabir A; Henter J-I; Borgstrom B; Nordgren A; Hammarsjo A; Putti C; Mozzato C; Zuccarello D; Nishimura G; Bonafe L; Grigelioniene G; Unger S; Superti-Furga A
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2020;145(5):1452-1463

Long-term outcome of LRBA deficiency in 76 patients after various treatment modalities as evaluated by the immune deficiency and dysregulation activity (IDDA) score

Tesch VK; Abolhassani H; Shadur B; Zobel J; Mareika Y; Sharapova S; Karakoc-Aydiner E; Riviere JG; Garcia-Prat M; Moes N; Haerynck F; Gonzales-Granado LI; Santos Perez JL; Mukhina A; Shcherbina A; Aghamohammadi A; Hammarstrom L; Dogu F; Haskologlu S; Ikinciogullari AI; Bal SK; Baris S; Kilic SS; Karaca NE; Kutukculer N; Girschick H; Kolios A; Keles S; Uygun V; Stepensky P; Worth A; van Montfrans JM; Peters AMJ; Meyts I; Adeli M; Marzollo A; Padem N; Khojah AM; Chavoshzadeh Z; Stefanija MA; Bakhtiar S; Florkin B; Meeths M; Gamez L; Grimbacher B; Seppanen MRJ; Lankester A; Gennery AR; Seidel MG
Article: PEDIATRIC BLOOD & CANCER. 2020;67(4):e28184

Diagnostic challenges for a novel SH2D1A mutation associated with X-linked lymphoproliferative disease

Torralba-Raga L; Tesi B; Chiang SCC; Schlums H; Nordenskjoeld M; Horne A; Henter J-I; Meeths M; Abdelhaleem M; Weitzman S; Bryceson Y
Article: NATURE COMMUNICATIONS. 2019;10(1):3106

Human DEF6 deficiency underlies an immunodeficiency syndrome with systemic autoimmunity and aberrant CTLA-4 homeostasis

Serwas NK; Hoeger B; Ardy RC; Stulz SV; Sui Z; Memaran N; Meeths M; Krolo A; Petronczki OY; Pfajfer L; Hou TZ; Halliday N; Santos-Valente E; Kalinichenko A; Kennedy A; Mace EM; Mukherjee M; Tesi B; Schrempf A; Loizou JI; Kain R; Bidmon-Fliegenschnee B; Schickel J-N; Glauzy S; Huemer J; Garncarz W; Salzer E; Pierides I; Bilic I; Thiel J; Priftakis P; Banerjee PP; Foerster-Waldl E; Medgyesi D; Huber W-D; Orange JS; Meffre E; Sansom DM; Bryceson YT; Altman A; Boztug K
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2018;141(2):770-775.e1

Treatment of severe forms of LPS-responsive beige-like anchor protein deficiency with allogeneic hematopoietic stem cell transplantation

Seidel MG; Boehm K; Dogu F; Worth A; Thrasher A; Florkin B; Ikinciogullari A; Peters A; Bakhtiar S; Meeths M; Stepensky P; Meyts I; Sharapova SO; Gamez-Diaz L; Hammarstroem L; Ehl S; Grimbacher B; Gennery AR
Article: FRONTIERS IN IMMUNOLOGY. 2017;8:426

Differences in Granule Morphology yet Equally Impaired Exocytosis among Cytotoxic T Cells and NK Cells from Chediak-Higashi Syndrome Patients

Chiang SCC; Wood SM; Tesi B; Akar HH; Al-Herz W; Ammann S; Belen FB; Caliskan U; Kaya Z; Lehmberg K; Patiroglu T; Tokgoz H; Unuvar A; Introne WJ; Henter J-I; Nordenskjold M; Ljunggren H-G; Meeths M; Ehl S; Krzewski K; Bryceson YT
Article: GENOME MEDICINE. 2015;7:130

Targeted high-throughput sequencing for genetic diagnostics of hemophagocytic lymphohistiocytosis

Tesi B; Lagerstedt-Robinson K; Chiang SCC; Ben Bdira E; Abboud M; Belen B; Devecioglu O; Fadoo Z; Yeoh AEJ; Erichsen HC; Mottonen M; Akar HH; Hastbacka J; Kaya Z; Nunes S; Patiroglu T; Sabel M; Saribeyoglu ET; Tvedt TH; Unal E; Unal S; Unuvar A; Meeths M; Henter J-I; Nordenskjold M; Bryceson YT
Article: PEDIATRIC BLOOD & CANCER. 2015;62(2):346-352

Incidence and Clinical Presentation of Primary Hemophagocytic Lymphohistiocytosis in Sweden

Meeths M; Horne A; Sabel M; Bryceson YT; Henter J-I
Article: PEDIATRIC BLOOD & CANCER. 2014;61(12):2313-2315

Hematopoietic Stem Cell Transplantation of an Adolescent With Neurological Manifestations of Homozygous Missense PRF1 Mutation

Hussein AA; Hamadah T; Qandeel M; Sughayer M; Amarin R; Mansour A; Chiang SC; Al-Zaben A; Meeths M; Bryceson YT
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2014;211(6):1079-1091

Transcriptional regulation of Munc13-4 expression in cytotoxic lymphocytes is disrupted by an intronic mutation associated with a primary immunodeficiency

Cichocki F; Schlums H; Li H; Stache V; Holmes T; Lenvik TR; Chiang SCC; Miller JS; Meeths M; Anderson SK; Bryceson YT
Article: FRONTIERS IN IMMUNOLOGY. 2014;4:515

An N-terminal missense mutation in STX11 causative of FHLA abrogates syntaxin-11 binding to Munc18-2

Muller M-L; Chiang SCC; Meeths M; Tesi B; Entesarian M; Nilsson D; Wood SM; Nordenskjold M; Henter J-I; Naqvi A; Bryceson YT
Article: HAEMATOLOGICA. 2013;98(5):760-764

Development of classical Hodgkin's lymphoma in an adult with biallelic STXBP2 mutations

Machaczka M; Klimkowska M; Chiang SCC; Meeths M; Muller M-L; Gustafsson B; Henter J-I; Bryceson YT
Article: BLOOD. 2013;121(8):1345-1356

Comparison of primary human cytotoxic T-cell and natural killer cell responses reveal similar molecular requirements for lytic granule exocytosis but differences in cytokine production

Chiang SCC; Theorell J; Entesarian M; Meeths M; Mastafa M; Al-Herz W; Frisk P; Gilmour KC; Ifversen M; Langenskiold C; Machaczka M; Naqvi A; Payne J; Perez-Martinez A; Sabel M; Unal E; Unal S; Winiarski J; Nordenskjold M; Ljunggren H-G; Henter J-I; Bryceson YT
Article: JOURNAL OF MEDICAL GENETICS. 2011;48(5):343-352

Genotype-phenotype study of familial haemophagocytic lymphohistiocytosis type 3

Sieni E; Cetica V; Santoro A; Beutel K; Mastrodicasa E; Meeths M; Ciambotti B; Brugnolo F; zur Stadt U; Pende D; Moretta L; Griffiths GM; Henter J-I; Janka G; Arico M
Article: PEDIATRIC BLOOD & CANCER. 2011;56(4):654-657

Unusual Functional Manifestations of a Novel STX11 Frameshift Mutation in Two Infants With Familial Hemophagocytic Lymphohistiocytosis Type 4 (FHL4)

Macartney CA; Weitzman S; Wood SM; Bansal D; Steele M; Meeths M; Abdelhaleem M; Bryceson YT
Article: PEDIATRIC BLOOD & CANCER. 2010;54(4):563-572

Clinical Presentation of Griscelli Syndrome Type 2 and Spectrum of RAB27A Mutations

Meeths M; Bryceson YT; Rudd E; Zheng C; Wood SM; Ramme K; Beutel K; Hasle H; Heilmann C; Hultenby K; Ljunggren H-G; Fadeel B; Nordenskjold M; Henter J-I
Article: BLOOD. 2009;114(19):4117-4127

Different NK cell-activating receptors preferentially recruit Rab27a or Munc13-4 to perforin-containing granules for cytotoxicity

Wood SM; Meeths M; Chiang SCC; Bechensteen AG; Boelens JJ; Heilmann C; Horiuchi H; Rosthoj S; Rutynowska O; Winiarski J; Stow JL; Nordenskjold M; Henter J-I; Ljunggren H-G; Bryceson YT
Article: PEDIATRIC BLOOD & CANCER. 2009;52(2):268-272

Treatment of the X-Linked Lymphoproliferative, Griscelli and Chediak-Higashi Syndromes by HLH Directed Therapy

Trottestam H; Beutel K; Meeths M; Carlsen N; Heilmann C; Pasic S; Webb D; Hasle H; Henter J-I
Journal article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009;106(2):468-473

Mice lacking asparaginyl endopeptidase develop disorders resembling hemophagocytic syndrome

Chan C-B; Abe M; Hashimoto N; Hao C; Williams IR; Liu X; Nakao S; Yamamoto A; Li S-Y; Hara-Nishimura I; Asano M; Ye K
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Alla övriga publikationer

Review: ACTA PAEDIATRICA. 2021;110(11):2903-2911

Genetics and pathophysiology of haemophagocytic lymphohistiocytosis

Meeths M; Bryceson YT
Corrigendum: NATURE COMMUNICATIONS. 2019;10(1):4555

Human DEF6 deficiency underlies an immunodeficiency syndrome with systemic autoimmunity and aberrant CTLA-4 homeostasis (vol 10, pg 3106, 2019)

Serwas NK; Hoeger B; Ardy RC; Stulz SV; Sui Z; Memaran N; Meeths M; Krolo A; Petronczki OY; Pfajfer L; Hou TZ; Halliday N; Santos-Valente E; Kalinichenko A; Kennedy A; Mace EM; Mukherjee M; Tesi B; Schrempf A; Pickl WF; Loizou JI; Kain R; Bidmon-Fliegenschnee B; Schickel J-N; Glauzy S; Huemer J; Garncarz W; Salzer E; Pierides I; Bilic I; Thiel J; Priftakis P; Banerjee PP; Foerster-Waldl E; Medgyesi D; Huber W-D; Orange JS; Meffre E; Sansom DM; Bryceson YT; Altman A; Boztug K
Editorial comment: BLOOD. 2016;127(17):2051-2052

HLH susceptibility: genetic lesions add up

Meeths M; Bryceson YT
Review: EXPERIMENTAL CELL RESEARCH. 2014;325(1):10-17

Pathophysiology and spectrum of diseases caused by defects in lymphocyte cytotoxicity

Meeths M; Chiang SCC; Lofstedt A; Muller M-L; Tesi B; Henter J-I; Bryceson YT
Letter: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2014;134(1):226-228

Combined newborn screening for familial hemophagocytic lymphohistiocytosis and severe T- and B-cell immunodeficiencies

Borte S; Meeths M; Liebscher I; Krist K; Nordenskjold M; Hammarstrom L; von Dobeln U; Henter J-I; Bryceson YT
Letter: BRITISH JOURNAL OF HAEMATOLOGY. 2013;162(3):415-418

Novel deep intronic and missense UNC13D mutations in familial haemophagocytic lymphohistiocytosis type 3

Entesarian M; Chiang SCC; Schlums H; Meeths M; Chan M-Y; Mya S-N; Soh S-Y; Nordenskjold M; Henter J-I; Bryceson YT
Thesis / dissertation: 2012

Genetic, cellular and clinical studies of hemophagocytic lymphohistiocytosis

Meeths, Marie
Letter: BRITISH JOURNAL OF HAEMATOLOGY. 2009;146(2):218-220

Multiple inherited sequence variations in two disease-causing genes in familial haemophagocytic lymphohistiocytosis

Rudd E; Meeths M; Uysal Z; Nordenskjoeld M; Henter J-I; Fadeel B
Corrigendum: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009;106(14):6023

Mice lacking asparaginyl endopeptidase develop disorders resembling hemophagocytic syndrome (vol 106, pg 468, 2008)

Chan C-B; Abe M; Hashimoto N; Hao C; Williams IR; Liu X; Nakao S; Yamamoto A; Zheng C; Henter J-I; Meeths M; Nordenskjold M; Li S-Y; Hara-Nishimura I; Asano M; Ye K

Anställningar

Anknuten till Forskning, Medicin, Huddinge, Karolinska Institutet, 2023-2026

Examina och utbildning

Medicine Doktorsexamen, Institutionen för kvinnors och barns hälsa, Karolinska Institutet, 2012
Läkarexamen, Karolinska Institutet, 2008

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Examina och utbildning

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