Maria Pernemalm

Om mig
Publikationer
CV
Populärvetenskap och samverkan

Om mig

See https://staff.ki.se/people/maria-pernemalm

Artiklar

Article: STEM CELL RESEARCH & THERAPY. 2024;15(1):77
Transcriptomic and proteomic profiles of fetal versus adult mesenchymal stromal cells and mesenchymal stromal cell-derived extracellular vesicles
Gencer EB; Lor YK; Abomaray F; El Andaloussi S; Pernemalm M; Sharma N; Hagey DW; Gorgens A; Gustafsson MO; Le Blanc K; Toonsi MA; Walther-Jallow L; Goetherstrom C
Article: NATURE COMMUNICATIONS. 2023;14(1):5921
Comprehensive proteomics and meta-analysis of COVID-19 host response
Babacic H; Christ W; Araujo JE; Mermelekas G; Sharma N; Tynell J; Garcia M; Varnaite R; Asgeirsson H; Glans H; Lehtioe J; Gredmark-Russ S; Klingstroem J; Pernemalm M
Article: RESPIRATORY RESEARCH. 2023;24(1):62
Targeted plasma proteomics reveals signatures discriminating COVID-19 from sepsis with pneumonia
Palma Medina LM; Babacic H; Dzidic M; Parke A; Garcia M; Maleki KT; Unge C; Lourda M; Kvedaraite E; Chen P; Muvva JR; Cornillet M; Emgard J; Moll K; Michaelsson J; Flodstrom-Tullberg M; Brighenti S; Buggert M; Mjosberg J; Malmberg K-JK; Sandberg J; Gredmark-Russ S; Rooyackers O; Svensson MJ; Chambers BI; Eriksson L; Pernemalm MK; Bjorkstrom N; Aleman S; Ljunggren H-G; Klingstrom J; Stralin K; Norrby-Teglund A
Article: MOLECULAR ONCOLOGY. 2023;17(2):238-260
Glioblastoma stem cells express non-canonical proteins and exclusive mesenchymal-like or non-mesenchymal-like protein signatures
Babacic H; Galardi S; Umer HM; Hellstrom M; Uhrbom L; Maturi N; Cardinali D; Pellegatta S; Michienzi A; Trevisi G; Mangiola A; Lehtio J; Ciafre SA; Pernemalm M
Article: FRONTIERS IN ENDOCRINOLOGY. 2022;13:971313
Proteome profiling of whole plasma and plasma-derived extracellular vesicles facilitates the detection of tissue biomarkers in the non-obese diabetic mouse
Lozano IMD; Sork H; Stone VM; Eldh M; Cao X; Pernemalm M; Gabrielsson S; Flodstrom-Tullberg M
Article: JOURNAL OF PROTEOME RESEARCH. 2021;20(9):4610-4620
Evaluation of Spin Columns for Human Plasma Depletion to Facilitate MS-Based Proteomics Analysis of Plasma
Cao X; Sandberg A; Araujo JE; Cvetkovski F; Berglund E; Eriksson LE; Pernemalm M
Article: NEOPLASIA. 2021;23(8):783-791
Plasma proteome alterations by MAPK inhibitors in BRAF^V600-mutated metastatic cutaneous melanoma
Babacic H; Eriksson H; Pernemalm M
Article: JOURNAL OF EXTRACELLULAR VESICLES. 2021;10(9):e12128
Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin
Veerman RE; Teeuwen L; Czarnewski P; Gucluler Akpinar G; Sandberg A; Cao X; Pernemalm M; Orre LM; Gabrielsson S; Eldh M
Article: MOLECULAR ONCOLOGY. 2021;15(2):429-461
High-throughput proteomics of breast cancer interstitial fluid: identification of tumor subtype-specific serologically relevant biomarkers
Terkelsen T; Pernemalm M; Gromov P; Borresen-Dale A-L; Krogh A; Haakensen VD; Lethio J; Papaleo E; Gromova I
Article: JOURNAL FOR IMMUNOTHERAPY OF CANCER. 2020;8(1):e000204
In-depth plasma proteomics reveals increase in circulating PD-1 during anti-PD-1 immunotherapy in patients with metastatic cutaneous melanoma
Babacic H; Lehtio J; de Coana YP; Pernemalm M; Eriksson H
Article: FRONTIERS IN ONCOLOGY. 2020;10:51
Immunometabolic Network Interactions of the Kynurenine Pathway in Cutaneous Malignant Melanoma
Rad Pour S; Morikawa H; Kiani NA; Gomez-Cabrero D; Hayes A; Zheng X; Pernemalm M; Lehtio J; Mole DJ; Hansson J; Eriksson H; Tegner J
Article: SCIENTIFIC REPORTS. 2019;9(1):16504
Early symptoms and sensations as predictors of lung cancer: a machine learning multivariate model
Levitsky A; Pernemalm M; Bernhardson B-M; Forshed J; Kolbeck K; Olin M; Henriksson R; Lehtio J; Tishelman C; Eriksson LE
Article: JOURNAL OF PROTEOME RESEARCH. 2019;18(9):3369-3382
Identification of a Biomarker Panel for Early Detection of Lung Cancer Patients
Geary B; Walker MJ; Snow JT; Lee DCH; Pernemalm M; Maleki-Dizaji S; Azadbakht N; Apostolidou S; Barnes J; Krysiak P; Shah R; Booton R; Dive C; Crosbie PA; Whetton AD
Article: NATURE COMMUNICATIONS. 2019;10(1):2331
The viral protein corona directs viral pathogenesis and amyloid aggregation
Ezzat K; Pernemalm M; Palsson S; Roberts TC; Jarver P; Dondalska A; Bestas B; Sobkowiak MJ; Levanen B; Skold M; Thompson EA; Saher O; Kari OK; Lajunen T; Ekstrom ES; Nilsson C; Ishchenko Y; Malm T; Wood MJA; Power UF; Masich S; Linden A; Sandberg JK; Lehtio J; Spetz A-L; EL Andaloussi S
Article: CLINICAL CANCER RESEARCH. 2019;25(10):3115-3127
Ultrasensitive Immunoprofiling of Plasma Extracellular Vesicles Identifies Syndecan-1 as a Potential Tool for Minimally Invasive Diagnosis of Glioma
Chandran VI; Welinder C; Mansson A-S; Offer S; Freyhult E; Pernemalm M; Lund SM; Pedersen S; Lehtio J; Marko-Varga G; Johansson MC; Englund E; Sundgren PC; Belting M
Article: ELIFE. 2019;8:e41608
In-depth human plasma proteome analysis captures tissue proteins and transfer of protein variants across the placenta
Pernemalm M; Sandberg A; Zhu Y; Boekel J; Tamburro D; Schwenk JM; Bjork A; Wahren-Herlenius M; Amark H; Ostenson C-G; Westgren M; Lehtio J
Article: CELL DEATH & DISEASE. 2017;8(8):e3029
Silencing FLI or targeting CD13/ANPEP lead to dephosphorylation of EPHA2, a mediator of BRAF inhibitor resistance, and induce growth arrest or apoptosis in melanoma cells
Azimi A; Tuominen R; Svedman FC; Caramuta S; Pernemalm M; Stolt MF; Kanter L; Kharaziha P; Lehtio J; Johansson CH; Holom V; Hansson J; Brage SE
Article: INTERNATIONAL JOURNAL OF CANCER. 2016;138(12):2984-2992
Protein Z: A putative novel biomarker for early detection of ovarian cancer
Russell MR; Walker MJ; Williamson AJK; Gentry-Maharaj A; Ryan A; Kalsi J; Skates S; D'Amato A; Dive C; Pernemalm M; Humphryes PC; Fourkala E-O; Whetton AD; Menon U; Jacobs I; Graham RLJ
Article: BMJ OPEN RESPIRATORY RESEARCH. 2016;3(1):e000114
ERK and AKT phosphorylation status in lung cancer and emphysema using nanocapillary isoelectric focusing
Crosbie PAJ; Crosbie EJ; Aspinall-O'Dea M; Walker M; Harrison R; Pernemalm M; Shah R; Joseph L; Booton R; Pierce A; Whetton AD
Article: EBIOMEDICINE. 2015;2(8):841-850
Discovery and Validation of Predictive Biomarkers of Survival for Non-small Cell Lung Cancer Patients Undergoing Radical Radiotherapy: Two Proteins With Predictive Value
Walker MJ; Zhou C; Backen A; Pernemalma M; Williamson AJK; Priest LJC; Koh P; Faivre-Finn C; Blackhall FH; Dive C; Whetton AD
Article: PLOS ONE. 2015;10(10):e0129008
Proteomics Analysis Reveals Distinct Corona Composition on Magnetic Nanoparticles with Different Surface Coatings: Implications for Interactions with Primary Human Macrophages
Vogt C; Pernemalm M; Kohonen P; Laurent S; Hultenby K; Vahter M; Lehtio J; Toprak MS; Fadeel B
Article: BIOMED RESEARCH INTERNATIONAL. 2015;2015:462549-13
Identifying and Assessing Interesting Subgroups in a Heterogeneous Population
Lee W; Alexeyenko A; Pernemalm M; Guegan J; Dessen P; Lazar V; Lehtio J; Pawitan Y
Article: PLOS ONE. 2015;10(5):e0126472
Differential Protein Expression Profiles of Cyst Fluid from Papillary Thyroid Carcinoma and Benign Thyroid Lesions
Dinets A; Pernemalm M; Kjellin H; Sviatoha V; Sofiadis A; Juhlin CC; Zedenius J; Larsson C; Lehtio J; Hoog A
Article: BRITISH JOURNAL OF CANCER. 2014;110(10):2489-2495
Proteomics analysis of melanoma metastases: association between S100A13 expression and chemotherapy resistance
Azimi A; Pernemalm M; Stolt MF; Hansson J; Lehtio J; Brage SE; Johansson CH
Article: JOURNAL OF PROTEOME RESEARCH. 2013;12(9):3934-3943
Quantitative Proteomics Profiling of Primary Lung Adenocarcinoma Tumors Reveals Functional Perturbations in Tumor Metabolism
Pernemalm M; De Petris L; Branca RM; Forshed J; Kanter L; Soria J-C; Girard P; Validire P; Pawitan Y; van den Oord J; Lazar V; Pahlman S; Lewensohn R; Lehtio J
Article: JOURNAL OF PROTEOME RESEARCH. 2013;12(2):1014-1019
A Novel Prefractionation Method Combining Protein and Peptide Isoelectric Focusing in Immobilized pH Gradient Strips
Pernemalm M; Lehtio J
Article: METHODS IN MOLECULAR BIOLOGY. 2013;1023:3-11
Narrow-range peptide isoelectric focusing as peptide prefractionation method prior to tandem mass spectrometry analysis.
Pernemalm M
Article: BMC BIOINFORMATICS. 2012;13:226
Network enrichment analysis: extension of gene-set enrichment analysis to gene networks
Alexeyenko A; Lee W; Pernemalm M; Guegan J; Dessen P; Lazar V; Lehtio J; Pawitan Y
Article: MOLECULAR & CELLULAR PROTEOMICS. 2011;10(10):M111.010264
Enhanced Information Output From Shotgun Proteomics Data by Protein Quantification and Peptide Quality Control (PQPQ)
Forshed J; Johansson HJ; Pernemalm M; Branca RMM; Sandberg A; Lehtio J
Article: PROTEOME SCIENCE. 2010;8:9
A novel method for sample preparation of fresh lung cancer tissue for proteomics analysis by tumor cell enrichment and removal of blood contaminants
De Petris L; Pernemalm M; Elmberger G; Bergman P; Orre L; Lewensohn R; Lehtio J
Article: PROTEOMICS. 2009;9(13):3414-3424
Use of narrow-range peptide IEF to improve detection of lung adenocarcinoma markers in plasma and pleural effusion
Pernemalm M; De Petris L; Eriksson H; Branden E; Koyi H; Kanter L; Lewensohn R; Lehtio J
Article: LUNG CANCER. 2009;63(3):410-417
Tumor expression of S100A6 correlates with survival of patients with stage I non-small-cell lung cancer
De Petris L; Orre LM; Kanter L; Pernemalm M; Koyi H; Lewensohn R; Lehtio J
Article: JOURNAL OF PROTEOME RESEARCH. 2008;7(7):2712-2722
Evaluation of three principally different intact protein prefractionation methods for plasma biomarker discovery
Pernemalm M; Orre LM; Lengqvist J; Wikstrom P; Lewensohn R; Lehtio J
Article: JOURNAL OF PROTEOME RESEARCH. 2008;7(6):2332-2341
Proteomic data analysis workflow for discovery of candidate biomarker peaks predictive of clinical outcome for patients with acute myeloid leukemia
Forshed J; Pernemalm M; Tan CS; Lindberg M; Kanter L; Pawitan Y; Lewensohn R; Stenke L; Lehtio J
Article: MOLECULAR & CELLULAR PROTEOMICS. 2007;6(12):2122-2131
Up-regulation, modification, and translocation of S100A6 induced by exposure to ionizing radiation revealed by proteomics profiling
Orre LM; Pernemalm M; Lengqvist J; Lewensohn R; Lehtio J
Article: PROTEOMICS. 2006;6(23):6124-6133
Annotated regions of significance of SELDI-TOF-MS spectra for detecting protein biornarkers
Tan CS; Ploner A; Quandt A; Lehtio J; Pernemalm M; Lewensohn R; Pawitan Y
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Alla övriga publikationer

Review: JOURNAL OF PROTEOME RESEARCH. 2021;20(12):5241-5263
Advances and Utility of the Human Plasma Proteome
Deutsch EW; Omenn GS; Sun Z; Maes M; Pernemalm M; Palaniappan KK; Letunica N; Vandenbrouck Y; Brun V; Tao S-C; Yu X; Geyer PE; Ignjatovic V; Moritz RL; Schwenk JM
Review: CANCER TREATMENT REVIEWS. 2015;41(4):361-375
Molecular histology of lung cancer: From targets to treatments
Wood SL; Pernemalm M; Crosbie PA; Whetton AD
Review: EXPERT REVIEW OF PROTEOMICS. 2014;11(4):431-448
Mass spectrometry-based plasma proteomics: state of the art and future outlook
Pernemalm M; Lehtio J
Review: CANCER TREATMENT REVIEWS. 2014;40(4):558-566
The role of the tumor-microenvironment in lung cancer-metastasis and its relationship to potential therapeutic targets
Wood SL; Pernemalm M; Crosbie PA; Whetton AD
Thesis / dissertation: 2009
Cancer proteomics : method development for mass spectrometry based analysis of clinical materials
Pernemalm, Maria
Review: PROTEOMICS. 2009;9(6):1420-1427
Affinity prefractionation for MS-based plasma proteomics
Pernemalm M; Lewensohn R; Lehtio J
Meeting abstract: JOURNAL OF THORACIC ONCOLOGY. 2007;2(8):S356-S357
Mass spectrometry profiling of low molecular weight platelet Proteome for the detection of lung cancer specific biomarkers
De Petris L; Pernemalm M; Branden E; Koyi H; Forshed J; Sundelin B; Lewensohn R; Lehtio J

Anställningar

Senior Forskare, Onkologi-Patologi, Karolinska Institutet, 2022-

Examina och utbildning

Docent, Medicinsk proteomik, Karolinska Institutet, 2022
Medicine Doktorsexamen, Institutionen för onkologi-patologi, Karolinska Institutet, 2009
Medicine Magisterexamen, Karolinska Institutet, 2005

Om mig

Artiklar

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Anställningar

Examina och utbildning

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