Maria Pernemalm

Maria Pernemalm

Principal Researcher | Docent
Visiting address: SciLifeLab, Tomtebodavägen 23A, 17121 Solna
Postal address: K7 Onkologi-Patologi, K7 Forskning Lehtiö, 171 77 Stockholm

About me

  • The analysis of human blood plasma with modern -omics technologies holds an
    enormous potential to reveal biomarkers for diagnosis and treatment
    selection, as well as studying complex systemic signalling events that are
    involved in immune modulation, metastatic spread and disease progression.
    My primary research interest is exploring how events on tissue and cellular
    level are reflected on the molecular level in human blood plasma and how
    these can be monitored using -omics methods. I have a long-standing interest
    and expertise in method development for mass spectrometry (MS) based plasma
    proteomics and in combining different analytical approaches and data sources
    with the aim to improve the understanding of the dynamics in the plasma
    proteome, in particularly related to biomarker discovery in lung cancer and
    malignant melanoma.
    The plasma team works both on method development and applied projects
    involving expanded applications of plasma proteome analysis such as plasma
    protein interaction with viruses and nanoparticles, proteogenomics biomarker
    discovery, and approaches to combine biochemical plasma markers with symptoms
    clusters for improved accuracy and sensitivity in precision medicine.
    *2022* Associate professor in Medical Proteomics, KI, Dept. Oncology
    Pathology
    *2009* PhD KI, Dept. Oncology Pathology
    *2010-2011* KI, Dept. Oncology Pathology, Post Doc
    *2011-2012* Scilifelab/KI/Dept. Oncology Pathology, Post Doc
    *2012-2013* The University of Manchester, Stem cell & leukemia proteomics
    lab, Post Doc
    *2013-2014* Scilifelab/KI/Dept. Oncology Pathology, Post Doc
    *2014-* Scilifelab/KI/Dept. Oncology Pathology, Assistant professor

Articles

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Employments

  • Principal Researcher, Department of Oncology-Pathology, Karolinska Institutet, 2022-

Degrees and Education

  • Docent, Karolinska Institutet, 2022
  • Degree Of Doctor Of Philosophy, Department of Oncology-Pathology, Karolinska Institutet, 2009
  • Master Of Medical Science, Karolinska Institutet, 2005

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