Maria Kippler
Lektor | Docent
E-postadress: maria.kippler@ki.se
Besöksadress: Nobels väg 13, 17177 Stockholm
Postadress: C6 Institutet för miljömedicin, C6 Metaller och hälsa Kippler, 171 77 Stockholm
Om mig
- Docent i miljömedicin vid Karolinska Institutet, Institutet för
Miljömedicin, Enheten för Metaller och Hälsa.
PhD i Medicinsk Vetenskap, Karolinska Institutet, 2009.
MSc i Toxicologi, Karolinska Institutet, 2004.
Forskningsbeskrivning
- Den övergripnade målsättningen med forskningen som utförs i min
forskningsgrupp att öka kunskapen om hur exponering för miljöföreningar,
framför allt metaller, tidigit i livet kan påverka barns hälsa
och utveckling. Vi studerar även betydelsen av essentiella spårelement och
andra näringsämnen (t.ex. selen och jod) och om det förekommer
interaktioner mellan dessa och olika toxiska metaller. Detta uppnås genom
att kombinera epidemiologiska och mekanistiska studier i material från olika
mor-barn kohorter. Metaller och andra spårelement mätts framför allt med
induktivt kopplad plasmamasspektrometri (ICP-MS), vilket möjliggör analys
ett flertal element i låga doser på mycket kort tid. Effektbiomarkörer
mätts med flera olika metoder.
Artiklar
- Article: JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY. 2025;91:127717Akhtar E; Roy AK; Haq MA; Jakarea M; Ara A; Naheed A; Rahman MA; von Ehrenstein OS; Kippler M; Wagatsuma Y; Raqib R
- Article: ENVIRONMENTAL RESEARCH. 2025;278:121653Trask M; Rahman SM; Kampouri M; Raqib R; Ekstrom E-C; Kajantie E; Islam MR; Krais AM; Lindh C; Rahman A; Kippler M
- Article: INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH. 2025;266:114555Muthalagu A; Delsuz MS; Levi M; Kippler M; Frederiksen MW; Hansen BV; Christensen IB; Broberg K; Madsen AM
- Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2025;133(3-4):047008Singh T; Gustin K; Rahman SM; Shiraji S; Tofail F; Vahter M; Kampouri M; Kippler M
- Article: GLOBAL HEALTH ACTION. 2024;17(1):2390269Rahman S; Wallberg L; Rahman A; Ekstrom E-C; Kippler M; Hamadani JD; Rahman SM
- Article: ENVIRONMENTAL RESEARCH. 2024;263(Pt 2):120123Kampouri M; Zander E; Gustin K; Sandin A; Barman M; Sandberg A-S; Wold AE; Bolte S; Kippler M; Vahter M
- Article: ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY. 2024;112:104583Haque F; Akhtar E; Chanda BC; Ara A; Haq MA; Sarker P; Kippler M; Wagatsuma Y; von Ehrenstein OS; Raqib R
- Article: JOURNAL OF EPIDEMIOLOGY AND GLOBAL HEALTH. 2024;14(3):987-1003Islam MR; Nystroem CD; Kippler M; Kajantie E; Loef M; Rahman SM; Ekstroem E-C
- Article: JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY. 2024;85:127486Kampouri M; Margetaki K; Koutra K; Kyriklaki A; Daraki V; Roumeliotaki T; Bempi V; Vafeiadi M; Kogevinas M; Chatzi L; Kippler M
- Article: ATMOSPHERIC RESEARCH. 2024;305:107423Scaramboni C; Farias CN; Vasconcellos PDC; Levi M; Sadiktsis I; Pozza SA; Umbuzeiro GDA; Watanabe T; Rodrigues PCDO; Grandis A; Buckeridge MS; Campos MLAM; Kippler M; Dreij K; Galva MFDO
- Article: CURRENT DEVELOPMENTS IN NUTRITION. 2024;8(7):103799Soderlund F; Gransten J; Patterson E; Lindroos AK; Lignell S; Donat-Vargas C; Barebring L; Larsson SC; Kippler M; Akesson A
- Article: JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY. 2024;34(4):688-698Yim G; Margetaki K; Romano ME; Kippler M; Vafeiadi M; Roumeliotaki T; Bempi V; Farzan SF; Chatzi L; Howe CG
- Article: ENVIRONMENT INTERNATIONAL. 2024;189:108798Igra AM; Trask M; Rahman SM; Dreij K; Lindh C; Krais AM; Persson L-A; Rahman A; Kippler M
- Article: METHODSX. 2024;12:102772Rahman M; Sultana J; Hasan SS; Nurunnahar S; Baker M; Raqib R; Rahman SM; Kippler M; Parvez SM
- Article: ENVIRONMENTAL RESEARCH. 2024;248:118355Grundeken M; Gustin K; Vahter M; Delaval M; Barman M; Sandin A; Sandberg A-S; Wold AE; Broberg K; Kippler M
- Article: EXPOSURE AND HEALTH. 2024;16(2):357-368Gustin K; Ekvall KO; Barman M; Jacobsson B; Sandin A; Sandberg A-S; Wold AE; Vahter M; Kippler M
- Article: REDOX BIOCHEM CHEM. 2023;5-6:100015Cheff DM; Skröder H; Akhtar E; Cheng Q; Hall MD; Raqib R; Kippler M; Vahter M; Arnér ESJ
- Article: MOVEMENT DISORDERS. 2023;38(12):2302-2307Zhao Y; Ray A; Broberg K; Kippler M; Lill CM; Vineis P; Katzke VA; Rodriguez-Barranco M; Chirlaque M-D; Guevara M; Gomez J-H; Hansen J; Panico S; Middleton LT; Masala G; Pala V; Vinagre-Aragon A; Zibetti M; Vermeulen R; Peters S
- Article: JOURNAL OF INTERNAL MEDICINE. 2023;294(3):358-369Donat-Vargas C; Guallar-Castillon P; Nystrom J; Larsson SC; Kippler M; Vahter M; Faxen-Irving G; Michaelsson K; Wolk A; Stenvinkel P; Akesson A
- Article: ENVIRONMENT INTERNATIONAL. 2023;178:108071Kampouri M; Gustin K; Stravik M; Barman M; Sandin A; Sandberg A-S; Wold AE; Vahter M; Kippler M
- Article: ENVIRONMENTAL RESEARCH. 2023;227:115787Rahman SM; Igra AM; Essig JY; Ekstrom E-C; Dreij K; Trask M; Lindh C; El Arifeen S; Rahman A; Krais AM; Kippler M
- Article: ENVIRONMENTAL RESEARCH. 2023;225:115576Stravik M; Gustin K; Barman M; Levi M; Sandin A; Wold AE; Sandberg A-S; Kippler M; Vahter M
- Article: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 2023;52(1):144-155Kampouri M; Tofail F; Rahman SM; Gustin K; Vahter M; Kippler M
- Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2023;131(2):27003Igra AM; Rahman A; Johansson ALV; Pervin J; Svefors P; El Arifeen S; Vahter M; Persson L-A; Kippler M
- Journal article: FRONTIERS IN NUTRITION. 2023;10:1142959Naser AM; Rahman SM; Kippler M
- Article: FRONTIERS IN NUTRITION. 2023;10:1058965Islam MR; Rahman SM; Selling K; Nasanen-Gilmore P; Kippler M; Kajantie E; Rahman A; Pervin J; Ekstrom E-C
- Article: JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE. 2022;35(25):9014-9022Ogge LE; Murray F; Modzelewska D; Lundqvist R; Nilsson S; Carre H; Kippler M; Wold AE; Sandberg A-S; Sandin A; Jacobsson B; Barman M
- Article: ENVIRONMENTAL RESEARCH. 2022;214(Pt 4):114129Kampouri M; Gustin K; Stravik M; Barman M; Levi M; Daraki V; Jacobsson B; Sandin A; Sandberg A-S; Wold AE; Vahter M; Kippler M
- Journal article: ISEE CONFERENCE ABSTRACTS. 2022;2022(1)Kampouri M; Gustin K; Stråvik M; Barman M; Levi M; Daraki V; Jacobsson B; Sandin A; Sandberg A-S; Wold A; Vahter M; Kippler M
- Article: JOURNAL OF NUTRITION. 2022;152(7):1737-1746Gustin K; Vahter M; Barman M; Jacobsson B; Skroder H; Filipsson Nystrom H; Sandin A; Sandberg A-S; Wold AE; Kippler M
- Article: ENVIRONMENT INTERNATIONAL. 2022;163:107188Gliga AR; Igra AM; Hellberg A; Engstrom K; Raqib R; Rahman A; Vahter M; Kippler M; Broberg K
- Article: ENVIRONMENT INTERNATIONAL. 2022;161:107114Tagt J; Helte E; Donat-Vargas C; Larsson SC; Michaelsson K; Wolk A; Vahter M; Kippler M; Akesson A
- Article: FRONTIERS IN NUTRITION. 2021;8:733602Stravik M; Gustin K; Barman M; Skroder H; Sandin A; Wold AE; Sandberg A-S; Kippler M; Vahter M
- Article: ENVIRONMENT INTERNATIONAL. 2021;157:106869Gustin K; Barman M; Skroder H; Jacobsson B; Sandin A; Sandberg A-S; Wold AE; Vahter M; Kippler M
- Article: ENVIRONMENTAL POLLUTION. 2021;289:117905Margetaki K; Vafeiadi M; Kampouri M; Roumeliotaki T; Karakosta P; Daraki V; Kogevinas M; Hu H; Kippler M; Chatzi L
- Article: ENVIRONMENT INTERNATIONAL. 2021;156:106738Malin Igra A; Warnqvist A; Rahman SM; Ekström E-C; Rahman A; Vahter M; Kippler M
- Article: ENVIRONMENT INTERNATIONAL. 2021;154:106562Rahman A; Kippler M; Pervin J; Tarafder C; Lucy IJ; Svefors P; El Arifeen S; Persson LA
- Journal article: ISEE CONFERENCE ABSTRACTS. 2021;2021(1)Howe CG; Margetaki K; Vafeiadi M; Roumeliotaki T; Karachaliou M; Kogevinas M; McConnell R; Eckel SP; Conti DV; Kippler M; Farzan SF; Chatzi L
- Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2021;129(4):47005Helte E; Vargas CD; Kippler M; Wolk A; Michaelsson K; Akesson A
- Article: ENVIRONMENTAL POLLUTION. 2021;271:116333Akhtar E; Roy AK; Haq MA; von Ehrenstein OS; Ahmed S; Vahter M; Ekstrom E-C; Kippler M; Wagatsuma Y; Raqib R
- Article: ENVIRONMENTAL HEALTH. 2021;20(1):1Howe CG; Margetaki K; Vafeiadi M; Roumeliotaki T; Karachaliou M; Kogevinas M; McConnell R; Eckel SP; Conti DV; Kippler M; Farzan SF; Chatzi L
- Article: ANNALS OF NEUROLOGY. 2021;89(1):125-133Peters S; Broberg K; Gallo V; Levi M; Kippler M; Vineis P; Veldink J; van den Berg L; Middleton L; Travis RC; Bergmann MM; Palli D; Grioni S; Tumino R; Elbaz A; Vlaar T; Mancini F; Kuehn T; Katzke V; Agudo A; Goni F; Gomez J-H; Rodriguez-Barranco M; Merino S; Barricarte A; Trichopoulou A; Jenab M; Weiderpass E; Vermeulen R
- Article: ENVIRONMENTAL POLLUTION. 2021;268(Pt A):115712Kippler M; Gyllenhammar I; Glynn A; Levi M; Lignell S; Berglund M
- Journal article: ISEE CONFERENCE ABSTRACTS. 2020;2020(1)Margetaki K; Stratakis N; Vafeiadi M; Roumeliotaki T; Vahter M; Kogevinas M; Kippler M; Chatzi L
- Journal article: ISEE CONFERENCE ABSTRACTS. 2020;2020(1)Gustin K; Barman M; Stråvik M; Levi M; Englund-Ögge L; Murray F; Jacobsson B; Sandberg A; Sandin A; Wold AE; Vahter M; Kippler M
- Journal article: ISEE CONFERENCE ABSTRACTS. 2020;2020(1)Helte E; Donat Vargas C; Kippler M; Wolk A; Michaëlsson K; Åkesson A
- Article: ENVIRONMENTAL POLLUTION. 2020;265(Pt B):114986Gustin K; Barman M; Stravik M; Levi M; Englund-Ogge L; Murray F; Jacobsson B; Sandberg A-S; Sandin A; Wold AE; Vahter M; Kippler M
- Article: ENVIRONMENT INTERNATIONAL. 2020;139:105723Vahter M; Skroder H; Rahman SM; Levi M; Hamadani JD; Kippler M
- Article: NANOMATERIALS. 2020;10(4):E618-618Cappellini F; Di Bucchianico S; Karri V; Latvala S; Malmlof M; Kippler M; Elihn K; Hedberg J; Wallinder IO; Gerde P; Karlsson HL
- Journal article: ENVIRONMENTAL EPIDEMIOLOGY. 2019;3(Supplement 1):260K M; M V; T R; P K; V D; G C; M V; M K; M K; L C
- Article: ENVIRONMENT INTERNATIONAL. 2019;126:1-6Akesson A; Donat-Vargas C; Berglund M; Glynn A; Wolk A; Kippler M
- Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2019;127(3):37003Igra AM; Vahter M; Raqib R; Kippler M
- Article: AMERICAN JOURNAL OF EPIDEMIOLOGY. 2019;188(1):141-150Chatzi L; Ierodiakonou D; Margetaki K; Vafeiadi M; Chalkiadaki G; Roumeliotaki T; Fthenou E; Pentheroudaki E; McConnell R; Kogevinas M; Kippler M
- Article: ENVIRONMENT INTERNATIONAL. 2018;121(Pt 1):842-851Skroder H; Kippler M; De Loma J; Raqib R; Vahter M
- Article: BMJ OPEN. 2018;8(10):e022013Barman M; Murray F; Bernardi AI; Broberg K; Bolte S; Hesselmar B; Jacobsson B; Jonsson K; Kippler M; Rabe H; Ross AB; Sjoberg F; Stromberg N; Vahter M; Wold AE; Sandberg A-S; Sandin A
- Article: ARCHIVES OF TOXICOLOGY. 2018;92(8):2487-2500Gliga AR; Engstrom K; Kippler M; Skroder H; Ahmed S; Vahter M; Raqib R; Broberg K
- Article: TOXICOLOGICAL SCIENCES. 2018;164(2):539-549Mannan T; Ahmed S; Akhtar E; Bin Ahsan K; Haq A; Kippler M; Vahter M; Raqib R
- Article: ENVIRONMENT INTERNATIONAL. 2018;113:259-268Cadmium exposure and cognitive abilities and behavior at 10 years of age: A prospective cohort studyGustin K; Tofail F; Vahter M; Kippler M
- Journal article: CIRCULATION. 2018;137(suppl_1)Kippler M; Donat Vargas C; Berglund M; Glynn A; Wolk A; Åkesson A
- Journal article: ISEE CONFERENCE ABSTRACTS. 2018;2017(1)Skröder H; Kippler M; Nermell B; Tofail F; Levi M; Rahman SM; Raqib R; Vahter M
- Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2018;126(2):027001Skroder H; Engstrom K; Kuehnelt D; Kippler M; Francesconi K; Nermell B; Tofail F; Broberg K; Vahter M
- Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2017;125(11):117003Skroder H; Kippler M; Tofail F; Vahter M
- Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2017;125(6):067021Skroder H; Rippler M; Nermell B; Tofail F; Levi M; Rahman SM; Raqib R; Vahter M
- Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2017;125(6):067006Raqib R; Ahmed S; Bin Ahsan K; Kippler M; Akhtar E; Roy AK; Lu Y; El Arifeen S; Wagatsuma Y; Vahter M
- Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2017;125(5):057003Rahman SM; Kippler M; Tofail F; Bolte S; Hamadani JD; Vahter M
- Article: ENVIRONMENT INTERNATIONAL. 2017;102:97-105Gustin K; Tofail F; Mehrin F; Levi M; Vahter M; Kippler M
- Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY. 2016;31(11):1123-1134Kippler M; Bottai M; Georgiou V; Koutra K; Chalkiadaki G; Kampouri M; Kyriklaki A; Vafeiadi M; Fthenou E; Vassilaki M; Kogevinas M; Vahter M; Chatzi L
- Article: AMERICAN JOURNAL OF CLINICAL NUTRITION. 2016;104(5):1318-1326Bouhouch RR; El-Fadeli S; Andersson M; Aboussad A; Chabaa L; Zeder C; Kippler M; Baumgartner J; Sedki A; Zimmermann MB
- Article: ENVIRONMENTAL RESEARCH. 2016;151:628-634Skroder H; Hawkesworth S; Moore SE; Wagatsuma Y; Kippler M; Vahter M
- Article: BRITISH JOURNAL OF CANCER. 2016;115(9):1113-1121Donat-Vargas C; Akesson A; Berglund M; Glynn A; Wolk A; Kippler M
- Journal article: REPRODUCTIVE TOXICOLOGY. 2016;64:16Broberg K; Kippler M
- Article: ENVIRONMENT INTERNATIONAL. 2016;94:706-711Kippler M; Larsson SC; Berglund M; Glynn A; Wolk A; Akesson A
- Article: PLOS ONE. 2016;11(8):e0161294Mannan T; Ahmed S; Akhtar E; Roy AK; Haq MA; Roy A; Kippler M; Ekstrom E-C; Wagatsuma Y; Raqib R
- Journal article: ISEE CONFERENCE ABSTRACTS. 2016;2016(1)Chatzi* L; Kippler M; Vafeiadi M; Pentheroudaki E; Roumeliotaki T; Chalkiadaki G; Fthenou E; Sarri K; Vassilaki M; Kogevinas M; Vahter M
- Journal article: ISEE CONFERENCE ABSTRACTS. 2016;2016(1)Löveborn* HS; Kippler M; Tofail F; Vahter M
- Journal article: ISEE CONFERENCE ABSTRACTS. 2016;2016(1)Vilahur* N; Malin* A; Ruiz C; Harari F; Runze L; Amaya E; Bustamante M; Kippler M; Fernandez MF; Olea N; Sunyer J; Broberg K
- Journal article: ISEE CONFERENCE ABSTRACTS. 2016;2016(1)Åkesson* A; Kippler M; Larsson S; Berglund M; Glynn A; Wolk A
- Journal article: ISEE CONFERENCE ABSTRACTS. 2016;2016(1)Donat-Vargas* C; Åkesson A; Berglund M; Glynn A; Wolk A; Kippler M
- Article: CELL BIOLOGY AND TOXICOLOGY. 2016;32(4):275-284Pournara A; Kippler M; Holmlund T; Ceder R; Grafstrom R; Vahter M; Broberg K; Wallberg AE
- Article: TOXICOLOGICAL SCIENCES. 2016;152(1):29-39Loveborn HS; Kippler M; Lu Y; Ahmed S; Kuehnelt D; Raqib R; Vahter M
- Article: TOXICOLOGICAL SCIENCES. 2016;149(2):473-483Wahlberg K; Kippler M; Alhamdow A; Rahman SM; Smith DR; Vahter M; Lucchini RG; Broberg K
- Article: ENVIRONMENT INTERNATIONAL. 2016;86:119-125Kippler M; Skroder H; Rahman SM; Tofail F; Vahter M
- Article: AMERICAN JOURNAL OF CLINICAL NUTRITION. 2015;102(6):1406-1415Kuehnelt D; Engstrom K; Skroder H; Kokarnig S; Schlebusch C; Kippler M; Alhamdow A; Nermell B; Francesconi K; Broberg K; Vahter M
- Article: CLINICAL NUTRITION. 2015;34(5):923-930Skroder HM; Hamadani JD; Tofail F; Persson TA; Vahter ME; Kippler MJ
- Article: ENVIRONMENTAL RESEARCH. 2015;140:205-213Skroder H; Hawkesworth S; Kippler M; El Arifeen S; Wagatsuma Y; Moore SE; Vahter M
- Article: REPRODUCTIVE TOXICOLOGY. 2015;53:68-74Rahman SM; Kippler M; Ahmed S; Palm B; El Arifeen S; Vahter M
- Article: CLINICAL BIOCHEMISTRY. 2015;48(3):140-147Lu Y; Kippler M; Harari F; Grander M; Palm B; Nordqvist H; Vahter M
- Article: ENVIRONMENTAL EPIGENETICS. 2015;1(1):dvv007Engstrom K; Rydbeck F; Kippler M; Wojdacz TK; Arifeen S; Vahter M; Broberg K
- Article: ENVIRONMENTAL RESEARCH. 2015;136:88-96Fagerstedt S; Kippler M; Scheynius A; Gutzeit C; Mie A; Alm J; Vahter M
- Article: JOURNAL OF INTERNAL MEDICINE. 2014;276(3):248-259Bergkvist C; Kippler M; Larsson SC; Berglund M; Glynn A; Wolk A; Akesson A
- Article: JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY. 2014;24(5):504-509Rydbeck F; Bottai M; Tofail F; Persson L-A; Kippler M
- Article: JOURNAL OF NUTRITION. 2014;144(9):1438-1444Rydbeck F; Rahman A; Grander M; Ekstrom E-C; Vahter M; Kippler M
- Article: TOXICOLOGICAL SCIENCES. 2014;141(1):166-175Ahmed S; Moore SE; Kippler M; Gardner R; Hawlader MDH; Wagatsuma Y; Raqib R; Vahter M
- Article: METALLOMICS. 2014;6(4):885-891Rentschler G; Kippler M; Axmon A; Raqib R; Skerfving S; Vahter M; Broberg K
- Article: PLOS ONE. 2013;8(9):e74119Rahman SM; Akesson A; Kippler M; Grander M; Hamadani JD; Streatfield PK; Persson L-A; El Arifeen S; Vahter M
- Article: AMERICAN JOURNAL OF EPIDEMIOLOGY. 2013;177(12):1356-1367Gardner RM; Kippler M; Tofail F; Bottai M; Hamadani J; Grander M; Nermell B; Palm B; Rasmussen KM; Vahter M
- Article: EPIGENETICS. 2013;8(5):494-503Kippler M; Engstrom K; Mlakar SJ; Bottai M; Ahmed S; Hossain MB; Raqib R; Vahter M; Broberg K
- Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2013;121(4):467-472Rentschler G; Kippler M; Axmon A; Raqib R; Ekstrom E-C; Skerfving S; Vahter M; Broberg K
- Article: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 2013;42(1):176-185Hawkesworth S; Wagatsuma Y; Kippler M; Fulford AJC; Arifeen SE; Persson L-A; Moore SE; Vahter M
- Article: REPRODUCTIVE TOXICOLOGY. 2012;34(4):504-511Kippler M; Wagatsuma Y; Rahman A; Nermell B; Persson L-A; Raqib R; Vahter M
- Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2012;120(10):1462-1468Kippler M; Tofail F; Hamadani JD; Gardner RM; Grantham-McGregor SM; Bottai M; Vahter M
- Article: TOXICOLOGICAL SCIENCES. 2012;129(2):305-314Ahmed S; Bin Ahsan K; Kippler M; Mily A; Wagatsuma Y; Hoque AMW; Ngom PT; El Arifeen S; Raqib R; Vahter M
- Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2012;120(2):284-289Kippler M; Tofail F; Gardner R; Rahman A; Hamadani JD; Bottai M; Vahter M
- Article: ENVIRONMENTAL RESEARCH. 2012;112:164-170Kippler M; Hossain MB; Lindh C; Moore SE; Kabir I; Vahter M; Broberg K
- Article: AMERICAN JOURNAL OF PUBLIC HEALTH. 2011;101(Suppl 1):S333-S338Gardner R; Hamadani J; Grander M; Tofail F; Nermell B; Palm B; Kippler M; Vahter M
- Journal article: ISEE CONFERENCE ABSTRACTS. 2011;2011(1)Kippler M; Tofail F; Gardner R; Hamadani J; Rahman A; Vahter M
- Article: REPRODUCTIVE TOXICOLOGY. 2011;31(2):210-218Gardner RM; Nermell B; Kippler M; Grander M; Li L; Ekstrom E-C; Rahman A; Loennerdal B; Hoque AMW; Vahter M
- Article: ENVIRONMENTAL RESEARCH. 2010;110(7):718-724Bergkvist C; Kippler M; Hamadani JD; Grander M; Tofail F; Berglund M; Vahter M
- Article: FREE RADICAL BIOLOGY AND MEDICINE. 2010;48(9):1211-1217Engstrom KS; Vahter M; Johansson G; Lindh CH; Teichert F; Singh R; Kippler M; Nermell B; Raqib R; Stromberg U; Broberg K
- Article: TOXICOLOGY LETTERS. 2010;192(2):162-168Kippler M; Hoque AMW; Raqib R; Ohrvik H; Ekstrom E-C; Vahter M
- Article: ENVIRONMENTAL RESEARCH. 2009;109(7):914-921Kippler M; Goessler W; Nermell B; Ekstrom EC; Lonnerdal B; El Arifeen S; Vahter M
- Article: ENVIRONMENTAL SCIENCE & TECHNOLOGY. 2009;43(7):2595-2601Ljung KS; Kippler MJ; Goessler W; Grander GM; Nermell BM; Vahter ME
- Article: TOXICOLOGY. 2009;257(1-2):64-69Kippler M; Loennerdal B; Goessler W; Ekstroem E-C; El Arifeen S; Vahter M
- Article: TOXICOLOGY AND APPLIED PHARMACOLOGY. 2007;222(2):221-226Kippler M; Ekstrom E-C; Lonnerdal B; Goessler W; Akesson A; El Arifeen S; Persson L-A; Vahter M
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Alla övriga publikationer
- Review: FOOD & NUTRITION RESEARCH. 2024;68Kippler M; Oskarsson A
- Review: FOOD & NUTRITION RESEARCH. 2023;67Kjellevold M; Kippler M
- Review: FOOD & NUTRITION RESEARCH. 2023;67Oskarsson A; Kippler M
- Conference publication: ISEE CONFERENCE ABSTRACTS. 2022;2022(1)Malin Igra A; Rahman A; Johansson ALV; Pervin J; Svefors P; El Arifeen S; Vahter M; Persson L-Å; Kippler M
- Book chapter: WHOLE GRAINS AND HEALTH. 2021;p. 337-350Kamal‐Eldin A; Åkesson A; Kippler M; Hellenäs K; Scheers N; Sandberg A
- Book chapter: A HANDBOOK OF ENVIRONMENTAL TOXICOLOGY: HUMAN DISORDERS AND ECOTOXICOLOGY. 2020;p. 384-393Åkesson A; Kippler M
- Conference publication: CIRCULATION. 2018;137Kippler M; Vargas CD; Berglund M; Glynn A; Wolk A; Akesson A
- Conference publication: ALLERGY. 2014;69:197Fagerstedt SA; Kippler M; Scheynius A; Mie A; Alm J; Vahter M
- Book chapter: ONE CENTURY OF THE DISCOVERY OF ARSENICOSIS IN LATIN AMERICA (1914-2014) AS2014: ARSENIC IN THE ENVIRONMENT - PROCEEDINGS. 2014;p. 8-12Vahter M; Ahmed S; Kippler M; Raqib R; Broberg K
- Conference publication: TOXICOLOGY LETTERS. 2012;211:S2Vahter M; Kippler M; Tofail F; Gardner R; Ahmed S; Broberg K; Hamadani J; Raqib R
- Conference publication: TOXICOLOGY LETTERS. 2012;211:S143Kippler M; Tofail F; Wagatsuma Y; Gardner R; Hamadani J; Rahman A; Vahter M
- Conference publication: TOXICOLOGY LETTERS. 2012;211:S133Ahmed S; Kippler M; Wagatsuma Y; Al-Arifeen S; Raqib R; Vahter M
- Published conference paper: TOXICOLOGY LETTERS. 2010;198(1):20-25Burden of cadmium in early childhood: Longitudinal assessment of urinary cadmium in rural BangladeshKippler M; Nermell B; Hamadani J; Tofail F; Moore S; Vahter M
- Doctoral thesis: 2009Kippler M
- Meeting abstract: TOXICOLOGY LETTERS. 2006;164:S200-S201Kippler M; Ekstrom E-C; Rahman A; Lonnerdal B; El Arifeen S; Persson L-A; Vahter M
Forskningsbidrag
- Swiss National Science Foundation1 April 2024 - 31 March 2028Global food production systems are under pressure to produce about double the current amount of food for about ten billion people by 2050 and are challenged by multiple stressors (e.g., emerging contamination with mycotoxins or pesticides, climate change, pest, and antibiotic residence, COVID-19 pandemic or wars). To tackle these challenges, the United Nations’ Sustainable Development Goals (SDG) foresee rethinking food production systems to safeguard environmental and public health and well-being. However, real-world evidence of trade-offs and impacts, particularly for food safety and security, is rare.Our proposal aims to advance human biomonitoring of food toxins (pesticides and mycotoxins) and several food quality biomarkers based on established cohorts with children, the most vulnerable population, from rural areas in South Africa, Switzerland and Sweden. On a broader scale, we will determine the impacts of food toxins and quality for the SDG key entry point, “food systems and nutrition patterns” and co-create with different national and international stakeholders collaborative actions to accelerate progress towards achieving the SDGs and bringing about the necessary transformations. We will develop our work along three work packages (WP) and objectives on well-established long-term collaborations between the University of Cape Town (UCT)Swiss Tropical and Public Health Institute (Swiss TPH), and Lund University as follows: WP1: To develop a large panel of laboratory methods to measure multiple pesticides, mycotoxins and food quality markers in existing urine samples from children in South Africa, Switzerland and Sweden (Objective 1: Quantitative analysis of pesticide, mycotoxin and food quality biomarkers)WP2: To study spatial and temporal patterns of food toxin mixtures and food quality markers and estimate potential risks using reversed dosimetry for children in South Africa, Switzerland and Sweden (Objective 2: Exposure and risk assessment of mycotoxins, pesticides and food quality)and Objective WP3: To semi-quantitatively evaluate trade-offs and the impacts for food safety and security towards the SDGs of food toxins and food quality for SDG 2, 3 and 12 and co-create selected risk mitigation scenarios with stakeholders in each country (Objective 3: Impacts towards SDGs and development of selected mitigation scenarios).Our transdisciplinary work will generate evidence on trade-offs and impacts for a vulnerable group (children) living in South Africa, Switzerland and Sweden. Next to peer-reviewed publications, our work co-creates mitigation scenarios, resulting in policy briefs for each country with recommendations for collaborative actions to accelerate progress towards achieving the SDGs and launch necessary transformations.
- Swedish Research Council for Environment Agricultural Sciences and Spatial Planning1 January 2023 - 31 December 2025Infants and children are particularly vulnerable in terms of food safety. The overall purpose of this 3-year project is to establish a scientific basis for a Swedish action plan to reduce toxic metals in food towards background levels. Like recently proposed by the US food and drug administration in their Closer to zero action plan, we prioritize arsenic, cadmium, lead, and mercury, but also fluoride and manganese, all of which have been detected in food and/or water and associated with impaired child development at fairly low exposure levels. This will be accomplished by measurements of metals in foods directed towards infants on the Swedish market, in combination with measuring well establish biomarkers of metal exposures and identifying major dietary sources in infants and young children (1, 1.5 and 4-year old’s) in the NICE cohort (n≈ 550) in northern Sweden and in Riksmaten young children (n=300) in middle and southern Sweden. Detailed dietary data is collected via food frequency questionnaires and food diaries. The exposure to metal mixtures at 4 years will also be related to data on child growth obtained from pediatric records using statistical models for mixtures, and we will conduct a scoping review on early childhood metal exposure and child growth. This will provide a strong scientific foundation for authorities in their work towards minimizing the exposure to metals via food through improved guidelines and policies to ensure the health of future generations.
- Swedish Research Council1 January 2023 - 31 December 2026Early life development is highly dependent on adequate nutrition, but also susceptible to toxic insult. Toxic metals, such as arsenic, cadmium, lead, manganese, and methylmercury (a toxic form of mercury), are commonly present in food, e.g., cereals, vegetables and fish, and drinking water. Lead and methylmercury are known to impair cognitive development at very low exposure levels, but little is known of the impact of the other metals with similar effects at the molecular level. Our research aims at closing the immense knowledge gap concerning effects of early-life exposure to metal mixtures on child growth, cognition, and behavior, i.e., health effects of major current concern in modern society.We are developing a toxicity arm in a newly established mother-child cohort, NICE, at Sunderby hospital, Norrbotten. We have discovered unexpectedly wide variations in the dietary exposure to cadmium, lead, methylmercury, and fluoride (mainly drinking water) during pregnancy, and identified adverse associations with pregnancy outcomes and thyroid function, independent of the identified prevalent deficiency of iodine and selenium in both mothers and young infants. We now seek funding to evaluate the impact of the toxic metals on growth (0-4 years), thyroid, cognition, and behavior at 4 years. At the end of 2022, we have about 600 children tested by Wechsler Preschool and Primary Scale of Intelligence, parents-completed questionnaires (CBCL, ABAS-2, SRS-2), and blood and urine sampled.
- Swedish Research Council1 January 2023 - 31 December 2025Emerging epidemiological data suggest that early-life exposure to metals and metal mixtures is associated with altered fetal and child growth, but underlying modes of action (MoAs) are largely unknown. The overall purpose of this 4-year project is to delineate underlying mechanisms of metal mixture toxicity by targeted and non-targeted approaches, combining data from a Swedish birth cohort (n=600) with an established developmental toxicity model. Metal mixtures (cadmium, lead, methylmercury, fluoride) have been measured during pregnancy, and in the children at 4 months and 4 years using well-established exposure biomarkers. These measurements will be related to several growth/bone-related hormones and bone remodeling markers at 4 years using statistical models designed for mixtures [Weighted Quantile Sum regression (WQS) and Bayesian Kernel Machine Regression (BKMR)]. In parallel, we will study morphological, functional and molecular effects of the metal’s mixtures on zebrafish development and growth, combining a targeted (morphometrics, hormone levels) and untargeted approach (RNAseq, metabolomics). Altogether, this will increase our understanding of MoAs for metal-induced adverse effects on child growth and critical windows of exposure, enable us to identify novel molecular markers for key events in these MoAs, and thereby strengthen causality in epidemiological data, all which can serve as tools for future health risk monitoring and preventive actions.
- Swedish Research Council1 January 2022 - 31 December 2024
- Swedish Research Council for Environment Agricultural Sciences and Spatial Planning1 January 2021 - 31 December 2024
- Swedish Research Council for Environment Agricultural Sciences and Spatial Planning1 January 2020 - 31 December 2022
- Swedish Research Council for Environment Agricultural Sciences and Spatial Planning1 January 2020 - 31 December 2022
- Swedish Research Council1 January 2019 - 31 December 2021
- Swedish Research Council for Environment Agricultural Sciences and Spatial Planning1 December 2018 - 30 November 2022
- Swedish Research Council1 January 2018 - 31 December 2020
- Swedish Research Council for Environment Agricultural Sciences and Spatial Planning1 January 2016 - 31 December 2018
- Swedish Research Council1 January 2016 - 31 December 2018
- Swedish Research Council1 January 2016 - 31 December 2018
- Swedish Research Council for Environment Agricultural Sciences and Spatial Planning1 January 2014 - 31 December 2016
Anställningar
- Lektor, Institutet för miljömedicin, Karolinska Institutet, 2020-
Examina och utbildning
- Docent, Miljömedicin, Karolinska Institutet, 2020
- Medicine Doktorsexamen, Institutet för miljömedicin, Karolinska Institutet, 2009
- Medicine Magisterexamen, Karolinska Institutet, 2004