Lena Palmberg

Om mig
Publikationer
Forskningsbidrag
CV
Populärvetenskap och samverkan

Om mig

Jag är läkare, professor och enhetschef för Integrativ toxikologi, på IMM.

Jag är studierektor för forskarutbildningen vid IMM, ordförande i disputat

Utbildning
- Professor i Toxikologi, september 2018 vid Karolinska Institutet
- Docent, mars 2000 vid Karolinska Institutet
- Disputerade, maj 1991, Karolinska Institutet
- Läkarexamen, januari 1988 Karolinska Institutetionskommittén vid Karolinska Institutet och lärarrepersentant i Kommittén för forskarutbildningen vid Karolinska Instittutet.

Forskningsbeskrivning

Målet med min forskning är att skapa en grund för effektiv framtida behandling genom ökad kunskap om bakomliggande mekanismer vid utvecklandet av kronisk bronkit och kroniskt obstruktiv lungsjukdom (KOL).

Undervisning

- Handleder doktorander och masterstudenter
- Undervisar på läkarprogrammet och masterutbildningen i toxikologi
- Föreläser på olika nivåer inom 3R och avancerade lungmodeller

Artiklar

Article: RESPIRATORY RESEARCH. 2024;25(1):49

Assessment of wood smoke induced pulmonary toxicity in normal- and chronic bronchitis-like bronchial and alveolar lung mucosa models at air-liquid interface

Upadhyay S; Rahman M; Rinaldi S; Koelmel J; Lin EZ; Mahesh PA; Beckers J; Johanson G; Pollitt KJG; Palmberg L; Irmler M; Ganguly K
Article: JOURNAL OF INFLAMMATION-LONDON. 2023;20(1):39

Lipid from electronic cigarette-aerosol both with and without nicotine induced pro-inflammatory macrophage polarization and disrupted phagocytosis

Rahman M; Sompa SI; Introna M; Upadhyay S; Ganguly K; Palmberg L
Article: BMJ OPEN. 2023;13(7):e072582

Assessing tobacco use in Swedish young adults from self-report and urinary cotinine: a validation study using the BAMSE birth cohort

Zettergren A; Sompa S; Palmberg L; Ljungman P; Pershagen G; Andersson N; Lindh C; Georgelis A; Kull I; Melen E; Ekstrom S; Bergstrom A
Article: TOXICS. 2023;11(6):532

Comparable Response Following Exposure to Biodiesel and Diesel Exhaust Particles in Advanced Multicellular Human Lung Models

Rahman M; Upadhyay S; Ganguly K; Introna M; Ji J; Boman C; Muala A; Blomberg A; Sandstrom T; Palmberg L
Article: LANCET REGIONAL HEALTH-EUROPE. 2023;28:100608

Ambient air pollution exposure linked to long COVID among young adults: a nested survey in a population-based cohort in Sweden

Yu Z; Ekstrom S; Bellander T; Ljungman P; Pershagen G; Eneroth K; Kull I; Bergstrom A; Georgelis A; Stafoggia M; Gruzieva O; Melen E
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2023;53(2):186-197

Exploring proteomic plasma biomarkers in eosinophilic and neutrophilic asthma

Kere M; Klevebro S; Hernandez-Pacheco N; Odling M; Ekstrom S; Mogensen I; Janson C; Palmberg L; van Hage M; Georgelis A; Bergstrom A; Kull I; Melen E; Bjorkander S
Article: SCIENTIFIC REPORTS. 2022;12(1):16396

Insight into the pulmonary molecular toxicity of heated tobacco products using human bronchial and alveolar mucosa models at air-liquid interface

Rahman M; Irmler M; Introna M; Beckers J; Palmberg L; Johanson G; Upadhyay S; Ganguly K
Article: TOXICS. 2022;10(6):277

Establishment of Repeated In Vitro Exposure System for Evaluating Pulmonary Toxicity of Representative Criteria Air Pollutants Using Advanced Bronchial Mucosa Models

Upadhyay S; Chakraborty A; Thimraj TA; Baldi M; Steneholm A; Ganguly K; Gerde P; Ernstgard L; Palmberg L
Article: ENVIRONMENTAL RESEARCH. 2022;208:112760

Predictors of electronic cigarette use and its association with respiratory health and obesity in young adulthood in Sweden; findings from the population-based birth cohort BAMSE

Sompa SI; Zettergren A; Ekstrom S; Upadhyay S; Ganguly K; Georgelis A; Ljungman P; Pershagen G; Kull I; Melen E; Palmberg L; Bergstrom A
Article: J ALLERGY CLIN IMMUNOL GLOB. 2022;1(2):37-42

Lung function before and after COVID-19 in young adults: A population-based study.

Mogensen I; Hallberg J; Björkander S; Du L; Zuo F; Hammarström L; Pan-Hammarström Q; Ekström S; Georgelis A; Palmberg L; Janson C; Bergström A; Melén E; Kull I; BAMSE COVID-19 Study Group
Article: ERJ OPEN RESEARCH. 2022;8(2):154-2022

Lung function in young adulthood: differences between males and females with asthma

Mogensen I; Hallberg J; Palmberg L; Ekstrom S; Georgelis A; Melen E; Bergstrom A; Kull I
Article: JAMA NETWORK OPEN. 2022;5(4):e228109

Association of Short-term Air Pollution Exposure With SARS-CoV-2 Infection Among Young Adults in Sweden

Yu Z; Bellander T; Bergstrom A; Dillner J; Eneroth K; Engardt M; Georgelis A; Kull I; Ljungman P; Pershagen G; Stafoggia M; Melen E; Gruzieva O
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:1079775

Tartrate resistant acid phosphatase 5 (TRAP5) mediates immune cell recruitment in a murine model of pulmonary bacterial infection

Tanner L; Bergwik J; Bhongir RKV; Puthia M; Lang P; Ali MN; Welinder C; Onnerfjord P; Erjefalt JS; Palmberg L; Andersson G; Egesten A
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2022;17:993-1004

Biomarkers, Clinical Course, and Individual Needs in COPD Patients in Primary Care: The Study Protocol of the Stockholm COPD Inflammation Cohort (SCOPIC)

Lundh L; Larsson K; Linden A; Montgomery S; Palmberg L; Sandelowsky H
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2022;149(1):65-75.e8

SARS-CoV-2-specific B- and T-cell immunity in a population-based study of young Swedish adults

Bjorkander S; Du L; Zuo F; Ekstrom S; Wang Y; Wan H; Sherina N; Schoutens L; Andrell J; Andersson N; Georgelis A; Bergstrom A; Marcotte H; Kull I; Hammarstrom L; Melen E; Pan-Hammarstrom Q
Article: VIRUSES-BASEL. 2021;13(12):2537

Differential Effect of SARS-CoV-2 Spike Glycoprotein 1 on Human Bronchial and Alveolar Lung Mucosa Models: Implications for Pathogenicity

Rahman M; Irmler M; Keshavan S; Introna M; Beckers J; Palmberg L; Johanson G; Ganguly K; Upadhyay S
Article: TOXICS. 2021;9(9):208

Circulating Secretoglobin Family 1A Member 1 (SCGB1A1) Levels as a Marker of Biomass Smoke Induced Chronic Obstructive Pulmonary Disease

Veerapaneni VV; Upadhyay S; Thimraj TA; Siddaiah JB; Krishnarao CS; Lokesh KS; Thimmulappa R; Palmberg L; Ganguly K; Anand MP
Article: SCIENTIFIC REPORTS. 2020;10(1):20460

Addressing the challenges of E-cigarette safety profiling by assessment of pulmonary toxicological response in bronchial and alveolar mucosa models

Ganguly K; Nordstrom A; Thimraj TA; Rahman M; Ramstrom M; Sompa SI; Lin EZ; O'Brien F; Koelmel J; Ernstgard L; Johanson G; Pollitt KJG; Palmberg L; Upadhyay S
Article: BIOMED RESEARCH INTERNATIONAL. 2020;2020:3259723-13

Analysis of Acrolein Exposure Induced Pulmonary Response in Seven Inbred Mouse Strains and Human Primary Bronchial Epithelial Cells Cultured at Air-Liquid Interface

Johanson G; Dwivedi AM; Ernstgard L; Palmberg L; Ganguly K; Chen LC; Galdanes K; Gordon T; Upadhyay S
Article: TOXICS. 2020;8(3):E68-68

Clinical, Epidemiological and Experimental Approaches to Assess Adverse Health Outcomes of Indoor Biomass Smoke Exposure: Conclusions from An Indo-Swedish Workshop in Mysuru, January 2020

Anand MP; Larsson K; Johanson G; Phuleria HC; Ravindra PV; Ernstgard L; Mabalirajan U; Krishna M; Palmberg L; Pollitt KJG; Upadhyay S; Ganguly K
Article: CLINICAL SCIENCE. 2020;134(10):1107-1125

Increased MUC1 plus a larger quantity and complex size for MUC5AC in the peripheral airway lumen of long-term tobacco smokers

Padra M; Andersson A; Levanen B; Premaratne P; Asgeirsdottir H; Tengvall S; Christenson K; Stockfelt M; Bozinovski S; Yoshihara S; Lantz A-S; Palmberg L; Dahlen B; Larsson K; Qvarfordt I; Linden SK; Linden A
Article: TOXICOLOGY IN VITRO. 2019;61:104617

Evaluation of diacetyl mediated pulmonary effects in physiologically relevant air-liquid interface models of human primary bronchial epithelial cells

Thimraj TA; Sompa SI; Ganguly K; Ernstgard L; Johanson G; Palmberg L; Upadhyay S
Article: NANOTOXICOLOGY. 2019;13(10):1362-1379

Exposure of normal and chronic bronchitis-like mucosa models to aerosolized carbon nanoparticles: comparison of pro-inflammatory oxidative stress and tissue injury/repair responses

Ji J; Ganguly K; Mihai X; Sun J; Malmlof M; Gerde P; Upadhyay S; Palmberg L
Article: MUCOSAL IMMUNOLOGY. 2019;12(1):39-50

Osteopontin protects against lung injury caused by extracellular histones

Kasetty G; Papareddy P; Bhongir RKV; Ali MN; Mori M; Wygrecka M; Erjefalt JS; Hultgardh-Nilsson A; Palmberg L; Herwald H; Egesten A
Article: DISEASE MARKERS. 2018;2018:4949175-11

Putative Systemic Biomarkers of Biomass Smoke-Induced Chronic Obstructive Pulmonary Disease among Women in a Rural South Indian Population

Vishweswaraiah S; Thimraj TA; George L; Krishnarao CS; Lokesh KS; Siddaiah JB; Larsson K; Upadhyay S; Palmberg L; Anand MP; Ganguly K
Article: PARTICLE AND FIBRE TOXICOLOGY. 2018;15(1):19

Multi-cellular human bronchial models exposed to diesel exhaust particles: assessment of inflammation, oxidative stress and macrophage polarization

Ji J; Upadhyay S; Xiong X; Malmlof M; Sandstrom T; Gerde P; Palmberg L
Article: TOXICOLOGY IN VITRO. 2018;46:219-228

Inflammatory effects of acrolein, crotonaldehyde and hexanal vapors on human primary bronchial epithelial cells cultured at air-liquid interface

Dwivedi AM; Upadhyay S; Johanson G; Ernstgard L; Palmberg L
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2018;13:3611-3624

Cholinergic mechanisms in an organic dust mode l simulating an acute exacerbation in patients with COPD

Palmberg L; Sundblad B-M; Ji J; Karen J; Larsson K
Article: MOLECULAR MEDICINE. 2017;23:247-257

Interleukin-26 Production in Human Primary Bronchial Epithelial Cells in Response to Viral Stimulation: Modulation by Th17 cytokines

Che KF; Kaarteenaho R; Lappi-Blanco E; Levanen B; Sun J; Wheelock A; Palmberg L; Skold CM; Linden A
Article: PLOS ONE. 2017;12(1):e0170428

Development of Combining of Human Bronchial Mucosa Models with XposeALI® for Exposure of Air Pollution Nanoparticles

Ji J; Hedelin A; Malmlof M; Kessler V; Seisenbaeva G; Gerde P; Palmberg L
Article: OCCUPATIONAL AND ENVIRONMENTAL MEDICINE. 2016;73(10):648-655

Comparing human respiratory adverse effects after acute exposure to particulate matter in conventional and particle-reduced swine building environments

Hedelin AS; Sundblad B-M; Sahlander K; Wilkinson K; Seisenbaeva G; Kessler V; Larsson K; Palmberg L
Article: JOURNAL OF LIPID RESEARCH. 2016;57(9):1659-1669

Pulmonary epithelial cancer cells and their exosomes metabolize myeloid cell-derived leukotriene C₄ to leukotriene D₄

Lukic A; Ji J; Idborg H; Samuelsson B; Palmberg L; Gabrielsson S; Radmark O
Article: EUROPEAN RESPIRATORY JOURNAL. 2016;47(6):1645-1656

Linoleic acid-derived lipid mediators increase in a female-dominated subphenotype of COPD

Balgoma D; Yang M; Sjodin M; Snowden S; Karimi R; Levanen B; Merikallio H; Kaarteenaho R; Palmberg L; Larsson K; Erle DJ; Dahlen S-E; Dahlen B; Skold CM; Wheelock AM; Wheelock CE
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2016;11:2109-2116

Impact of tobacco smoking on cytokine signaling via interleukin-17A in the peripheral airways

Levanen B; Glader P; Dahlen B; Billing B; Qvarfordt I; Palmberg L; Larsson K; Linden A
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2016;11:1035-1043

Effects of budesonide on toll-like receptor expression in alveolar macrophages from smokers with and without COPD

Ji J; von Scheele I; Billing B; Dahlen B; Lantz A-S; Larsson K; Palmberg L
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2016;11:1005-1013

Extracellular cadmium in the bronchoalveolar space of long-term tobacco smokers with and without COPD and its association with inflammation

Sundblad B-M; Ji J; Levanen B; Midander K; Julander A; Larsson K; Palmberg L; Linden A
Article: INHALATION TOXICOLOGY. 2015;27(14):810-821

Acute effects of acrolein in human volunteers during controlled exposure

Dwivedi AM; Johanson G; Lorentzen JC; Palmberg L; Sjogren B; Ernstgard L
Article: RESPIRATORY MEDICINE. 2015;109(9):1164-1173

Long term effect and allergic sensitization in newly employed workers in laboratory animal facilities

Palmberg L; Sundblad B-M; Lindberg A; Kupczyk M; Sahlander K; Larsson K
Article: ACS NANO. 2015;9(1):146-163

Next-Generation Sequencing Reveals Low-Dose Effects of Cationic Dendrimers in Primary Human Bronchial Epithelial Cells

Feliu N; Kohonen P; Ji J; Zhang Y; Karlsson HL; Palmberg L; Nystrom A; Fadeel B
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2014;190(9):1022-1031

Interleukin-26 in Antibacterial Host Defense of Human Lungs Effects on Neutrophil Mobilization

Che KF; Tengvall S; Levanen B; Silverpil E; Smith ME; Awad M; Vikstrom M; Palmberg L; Qvarfordt I; Skold M; Linden A
Article: RESPIRATORY RESEARCH. 2014;15(1):104

Compartment differences of inflammatory activity in chronic obstructive pulmonary disease

Ji J; von Scheele I; Bergstrom J; Billing B; Dahlen B; Lantz A-S; Larsson K; Palmberg L
Article: EUROPEAN CLINICAL RESPIRATORY JOURNAL. 2014;1:24545

Interactions between alveolar epithelial cells and neutrophils under pro-inflammatory conditions.

von Schéele I; Larsson K; Palmberg L
Article: RESPIRATORY RESEARCH. 2013;14(1):47

Adhesion molecules in subjects with COPD and healthy non-smokers: a cross sectional parallel group study

Blidberg K; Palmberg L; James A; Billing B; Henriksson E; Lantz A-S; Larsson K; Dahlen B
Article: PLOS ONE. 2013;8(3):e59492

Dental Health in Smokers with and without COPD

Bergstrom J; Cederlund K; Dahlen B; Lantz A-S; Skedinger M; Palmberg L; Sundblad B-M; Larsson K
Article: RESPIROLOGY. 2012;17(5):854-860

Increased neutrophil migration in smokers with or without chronic obstructive pulmonary disease

Blidberg K; Palmberg L; Dahlen B; Lantz A-S; Larsson K
Article: INNATE IMMUNITY. 2012;18(3):503-510

Chemokine release by neutrophils in chronic obstructive pulmonary disease

Blidberg K; Palmberg L; Dahlen B; Lantz A-S; Larsson K
Article: PLOS ONE. 2012;7(2):e31646

Daily Exposure to Dust Alters Innate Immunity

Sahlander K; Larsson K; Palmberg L
Article: RESPIRATORY MEDICINE. 2011;105(8):1222-1230

Toll-like receptor expression in smokers with and without COPD

von Scheele I; Larsson K; Dahlen B; Billing B; Skedinger M; Lantz A-S; Palmberg L
Article: ACS NANO. 2011;5(7):5312-5324

Solution-Engineered Palladium Nanoparticles: Model for Health Effect Studies of Automotive Particulate Pollution

Wilkinson KE; Palmberg L; Witasp E; Kupczyk M; Feliu N; Gerde P; Seisenbaeva GA; Fadeel B; Dahlen S-E; Kessler VG
Article: PULMONARY PHARMACOLOGY & THERAPEUTICS. 2010;23(4):316-323

Effect of formoterol and budesonide on chemokine release, chemokine receptor expression and chemotaxis in human neutrophils

Strandberg K; Blidberg K; Sahlander K; Palmberg L; Larsson K
Article: INHALATION TOXICOLOGY. 2010;22(6):493-499

Budesonide enhances Toll-like receptor 2 expression in activated bronchial epithelial cells

von Scheele I; Larsson K; Palmberg L
Article: JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE. 2010;52(2):214-218

Increased Serum Levels of Soluble ST2 in Birch Pollen Atopics and Individuals Working in Laboratory Animal Facilities

Sahlander K; Larsson K; Palmberg L
Article: INNATE IMMUNITY. 2010;16(1):27-38

Altered innate immune response in farmers and smokers

Sahlander K; Larsson K; Palmberg L
Article: SCANDINAVIAN JOURNAL OF WORK ENVIRONMENT & HEALTH. 2009;35(5):376-383

Evaluation of respiratory effects related to high-pressure cleaning in a piggery with and without robot pre-cleaning

Hiel D; von Scheele I; Sundblad B-M; Larsson K; Palmberg L
Article: EUROPEAN RESPIRATORY JOURNAL. 2009;34(1):80-88

Repeated exposure to organic material alters inflammatory and physiological airway responses

Sundblad B-M; von Scheele I; Palmberg L; Olsson M; Larsson K
Article: JOURNAL OF INTERNAL MEDICINE. 2008;264(1):83-94

Fluticasone and ibuprofen do not add to the effect of salmeterol on organic dust-induced airway inflammation and bronchial hyper-responsiveness

Strandberg K; Ek A; Palmberg L; Larsson K
Article: JOURNAL OF ASTHMA. 2008;45(3):201-203

Effect of budesonide and formoterol on Il-6 and Il-8 release from primary bronchial epithelial cells

Strandberg K; Palmberg L; Larsson K
Article: RESPIRATORY MEDICINE. 2007;101(6):1132-1139

Effect of formoterol and salmeterol on IL-6 and IL-8 release in airway epithelial cells

Strandberg K; Palmberg L; Larsson K
Article: LIFE SCIENCES. 2007;80(17):1598-1607

Organic dust-induced activation, adhesion to substrate and expression of intercellular adhesion molecules in THP-1 monocytes

Burvall K; Palmberg L; Larsson K
Article: JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE. 2007;49(2):131-138

Differential pattern of human blood neutrophil activation after stimulation with organic dust in vitro and in vivo

Jonsson EW; Palmberg L
Article: ALLERGY. 2006;61(12):1473-1479

Release of prostaglandin D₂ and leukotriene C₄ in response to hyperosmolar stimulation of mast cells

Gulliksson M; Palmberg L; Nilsson G; Ahlstedt S; Kumlin M
Article: EUROPEAN RESPIRATORY JOURNAL. 2006;28(6):1229-1235

Saliva is one likely source of leukotriene B₄ in exhaled breath condensate

Gaber F; Acevedo F; Delin I; Sundblad B-M; Palmberg L; Larsson K; Kumlin M; Dahlen S-E
Article: SCANDINAVIAN JOURNAL OF WORK ENVIRONMENT & HEALTH. 2006;32(2):145-153

Effect of respirators equipped with particle or particle-and-gas filters during exposure in a pig confinement building

Sundblad B-M; Sahlander K; Ek A; Kumlin M; Olsson M; Larsson K; Palmberg L
Article: RESPIRATORY MEDICINE. 2006;100(2):226-237

Effects of 5-lipoxygenase inhibitor zileuton on airway responses to inhaled swine house dust in healthy subjects

Larsson BM; Kumlin M; Sundblad BM; Larsson K; Dahlén SE; Palmberg L
Article: CHEST. 2005;128(4):3038-3047

Salmeterol does not alter increased bronchial responsiveness caused by organic dust exposure

Ek A; Palmberg L; Sundblad BM; Larsson K
Article: INFLAMMATION RESEARCH. 2005;54(7):281-288

Expression of TNFalpha and its receptors R1 and R2 in human alveolar epithelial cells exposed to organic dust and the effects of 8-bromo-cAMP and protein kinase A modulation

Burvall K; Palmberg L; Larsson K
Article: RESPIRATORY RESEARCH. 2005;6(1):44

Interleukin-17A mRNA and protein expression within cells from the human bronchoalveolar space after exposure to organic dust -: art. no. 44

Ivanov S; Palmberg L; Venge P; Larsson K; Lindén A
Article: INFLAMMATION. 2005;29(1):39-45

Exposure to organic dust causes activation of human plasma complement factors C3 and B and the synthesis of factor C3 by lung epithelial cells in vitro

Acevedo F; Palmberg L; Larsson K
Article: LIFE SCIENCES. 2004;75(23):2733-2749

Influence of 8-bromo-cyclicAMP on interleukin-6 and-8 mRNA levels in A549 human lung epithelial cells exposed to organic dust: A time-kinetic study

Burvall K; Palmberg L; Larsson K
Article: EUROPEAN RESPIRATORY JOURNAL. 2004;24(4):587-593

The effect of fluticasone on the airway inflammatory response to organic dust

Ek A; Palmberg L; Larsson K
Article: SCANDINAVIAN JOURNAL OF WORK ENVIRONMENT & HEALTH. 2004;30(4):313-321

Acute respiratory effects of exposure to ammonia on healthy persons

Sundblad BM; Larsson BM; Acevedo F; Ernstgård L; Johanson G; Larsson K; Palmberg L
Article: RESPIRATORY MEDICINE. 2003;97(8):882-892

Organic dust activates NF-κB in lung epithelial cells

Lidén J; Ek A; Palmberg L; Okret S; Larsson K
Article: INFLAMMATION. 2003;27(2):71-78

Red blood cells stimulate human lung fibroblasts to secrete interleukin-8

Fredriksson K; Lundahl J; Palmberg L; Romberger DJ; Liu XD; Rennard SI; Skold CM
Article: RESPIRATORY MEDICINE. 2003;97(1):46-50

Effects by 8-bromo-cyclicAMP on basal and organic dust-induced release of interleukin-6 and interleukin-8 in A549 human airway epithelial cells

Burvall K; Palmberg L; Larsson K
Article: INFLAMMATION. 2002;26(6):291-296

Modulation of plasma levels of soluble adhesion molecules and nitric oxide in healthy volunteers by exposure to swine dust

Kölbeck KG; Sardh E; Gyllenhammar H; Palmberg L; Larsson K; Palmblad J
Article: MOLECULAR AND CELLULAR BIOCHEMISTRY. 2002;240(1-2):131-133

The tyrosine kinase inhibitor genistein increases basal cAMP and potentiates forskolin-induced cAMP accumulation in A549 human airway epithelial cells

Burvall KM; Palmberg L; Larsson K
Article: EUROPEAN RESPIRATORY JOURNAL. 2002;20(2):426-431

Exhaled nitric oxide and bronchial responsiveness in healthy subjects exposed to organic dust

Sundblad BM; Larsson BM; Palmberg L; Larsson K
Article: SCANDINAVIAN JOURNAL OF WORK ENVIRONMENT & HEALTH. 2002;28(4):256-263

Airway responses of healthy farmers and nonfarmers to exposure in a swine confinement building

Palmberg L; Larssson BM; Malmberg P; Larsson K
Article: CHEST. 2002;122(1):363-368

Bronchial responsiveness to eucapnic hyperventilation and methacholine following exposure to organic dust.

Sundblad B-M; Palmberg L; Larsson K
Article: LIFE SCIENCES. 2002;71(3):299-309

Metabolic activation of A549 human airway epithelial cells by organic dust: A study based on microphysiometry

Burvall K; Palmberg L; Larsson K
Article: AMERICAN JOURNAL OF INDUSTRIAL MEDICINE. 2002;41(4):250-258

Airways inflammation after exposure in a swine confinement building during cleaning procedure.

Larsson B-M; Larsson K; Malmberg P; Palmberg L
Article: EUROPEAN RESPIRATORY JOURNAL. 2002;19(3):534-537

Free, soluble interleukin-17 protein during severe inflammation in human airways

Laan M; Palmberg L; Larsson K; Lindén A
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2001;115(1):6-12

Swine dust induces cytokine secretion from human epithelial cells and alveolar macrophages.

Wang Z; Malmberg P; Ek A; Larsson K; Palmberg L
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2001;121(1):11-16

Influence of fluticasone and salmeterol on airway effects of inhaled organic dust;an in vivo and ex vivo study.

Ek A; Palmberg L; Larsson K
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2001;31(9):1356-1368

Sodium cromoglycate attenuates pulmonary inflammation without influencing bronchial responsiveness in healthy subjects exposed to organic dust.

Larsson K; Larsson BM; Sandström T; Sundblad BM; Palmberg L
Article: INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH. 2001;74(4):249-254

Albumin, transferrin and alpha2-macroglobulin in bronchoalveolar lavage fluid following exposure to organic dust in healthy subjects.

Vesterberg O; Palmberg L; Larsson K
Article: RESPIRATORY MEDICINE. 2000;94(11):1065-1072

Airway reactivity and exhaled NO following swine dust exposure in healthy volunteers

Kölbeck KG; Ehnhage A; Juto JE; Forsberg S; Gyllenhammar H; Palmberg L; Larsson K
Article: INDOOR AIR. 1999;9(4):219-225

House dust induces IL-6 and IL-8 response in A549 epithelial cells.

Saraf A; Larsson L; Larsson BM; Larsson K; Palmberg L
Article: ALLERGY. 1999;54(7):691-699

Fluticasone and budesonide inhibit cytokine release in human lung epithelial cells and alveolar macrophages.

Ek A; Larsson K; Siljerud S; Palmberg L
Article: INFLAMMATION. 1999;23(3):217-230

Gram positive bacteria induce IL-6 and IL-8 production in human alveolar macrophages and epithelial cells.

Larsson BM; Larsson K; Malmberg P; Palmberg L
Article: AMERICAN JOURNAL OF INDUSTRIAL MEDICINE. 1999;35(2):142-149

Airway responses in naive subjects to exposure in poultry houses: comparison between cage rearing system and alternative rearing system for laying hens.

Larsson BM; Larsson K; Malmberg P; Mártensson L; Palmberg L
Article: THORAX. 1998;53(12):1041-1046

Exposure of healthy volunteers to swine house dust increases formation of leukotrienes, prostaglandin D₂, and bronchial responsiveness to methacholine

O'Sullivan S; Dahlen SE; Larsson K; Larsson BM; Malmberg P; Kumlin M; Palmberg L
Article: EUROPEAN RESPIRATORY JOURNAL. 1998;12(4):825-830

Inhalation of cold air increases the number of inflammatory cells in the lungs in healthy subjects

Larsson K; Tornling G; Gavhed D; Muller-Suur C; Palmberg L
Article: THORAX. 1998;53(4):260-264

Induction of IL-8 production in human alveolar macrophages and human bronchial epithelial cells in vitro by swine dust.

Palmberg L; Larsson BM; Malmberg P; Larsson K
Article: RESPIRATORY MEDICINE. 1998;92(2):162-166

Budesonide but not terbutaline decreases phagocytosis in alveolar macrophages

Zetterlund A; Larsson PH; Muller-Suur C; Palmberg L; Larsson K
Article: ENVIRONMENTAL RESEARCH. 1997;75(2):141-148

Reaction of human alveolar macrophages to exposure to Aspergillus fumigatus and inert particles

Nessa K; Palmberg L; Johard U; Malmberg P; Jarstrand C; Camner P
Article: CARCINOGENESIS. 1997;18(11):2205-2208

DNA adducts in human nasal mucosa and white blood cells from smokers and non-smokers

Zhao CY; Georgellis A; Flato S; Palmberg L; Thunberg E; Hemminki K
Article: THORAX. 1997;52(7):638-642

Effect of exposure to swine dust on levels of IL-8 in airway lavage fluid.

Larsson BM; Palmberg L; Malmberg PO; Larsson K
Article: EUROPEAN RESPIRATORY JOURNAL. 1997;10(2):381-387

Inhalation of swine dust induces cytokine release in the upper and lower airways.

Wang Z; Larsson K; Palmberg L; Malmberg P; Larsson P; Larsson L
Article: OCCUPATIONAL AND ENVIRONMENTAL MEDICINE. 1996;53(9):586-590

Acute effects of exposure to air contaminants in a sawmill on healthy volunteers.

Dahlqvist M; Palmberg L; Malmberg P; Sundblad BM; Ulfvarson U; Zhiping W
Journal article: JOURNAL OF CELL SCIENCE. 1991;98:141-149

ON THE MECHANISM OF INDUCTION OF DNA-SYNTHESIS IN CULTURED ARTERIAL SMOOTH-MUSCLE CELLS BY LEUKOTRIENES - POSSIBLE ROLE OF PROSTAGLANDIN ENDOPEROXIDE SYNTHASE PRODUCTS AND PLATELET-DERIVED GROWTH-FACTOR

PALMBERG L; LINDGREN JA; THYBERG J; CLAESSON HE
Journal article: ARTERIOSCLEROSIS. 1990;10(6):966-990

REGULATION OF DIFFERENTIATED PROPERTIES AND PROLIFERATION OF ARTERIAL SMOOTH-MUSCLE CELLS

THYBERG J; HEDIN U; SJOLUND M; PALMBERG L; BOTTGER BA
Journal article: JOURNAL OF CELL SCIENCE. 1989;94 ( Pt 3):381-387

New insights into the evolutionary growth of tumors revealed by Southern gel analysis of tumors genetically tagged with plasmid or proviral DNA insertions.

Kerbel RS; Cornil I; Korczak B
Journal article: JOURNAL OF CELL SCIENCE. 1989;93:403-408

EFFECTS OF LEUKOTRIENES ON PHENOTYPIC PROPERTIES AND GROWTH OF ARTERIAL SMOOTH-MUSCLE CELLS IN PRIMARY CULTURE

PALMBERG L; CLAESSON HE; THYBERG J
Journal article: JOURNAL OF CELL SCIENCE. 1987;88:151-159

LEUKOTRIENES STIMULATE INITIATION OF DNA-SYNTHESIS IN CULTURED ARTERIAL SMOOTH-MUSCLE CELLS

PALMBERG L; CLAESSON HE; THYBERG J
Journal article: BIOLOGY OF THE CELL. 1987;60(2):125-132

THE CALCIUM-ANTAGONIST NISOLDIPINE AND THE CALMODULIN ANTAGONIST W-7 SYNERGISTICALLY INHIBIT INITIATION OF DNA-SYNTHESIS IN CULTURED ARTERIAL SMOOTH-MUSCLE CELLS

THYBERG J; PALMBERG L
Journal article: CELL AND TISSUE RESEARCH. 1986;246(2):253-262

UTERINE SMOOTH-MUSCLE CELLS IN PRIMARY CULTURE - ALTERATIONS IN FINE-STRUCTURE, CYTOSKELETAL ORGANIZATION AND GROWTH-CHARACTERISTICS

PALMBERG L; THYBERG J
Journal article: ATHEROSCLEROSIS. 1985;58(1-3):109-122

THE CALCIUM-ANTAGONIST NIFEDIPINE INHIBITS ARTERIAL SMOOTH-MUSCLE CELL-PROLIFERATION

NILSSON J; SJOLUND M; PALMBERG L; VONEULER AM; JONZON B; THYBERG J
Journal article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1985;82(13):4418-4422

ARTERIAL SMOOTH-MUSCLE CELLS IN PRIMARY CULTURE PRODUCE A PLATELET-DERIVED GROWTH FACTOR-LIKE PROTEIN

NILSSON J; SJOLUND M; PALMBERG L; THYBERG J; HELDIN CH
Journal article: DIFFERENTIATION. 1985;29(3):275-283

PHENOTYPE MODULATION IN PRIMARY CULTURES OF ARTERIAL SMOOTH-MUSCLE CELLS - REORGANIZATION OF THE CYTOSKELETON AND ACTIVATION OF SYNTHETIC ACTIVITIES

PALMBERG L; SJOLUND M; THYBERG J
Journal article: CELL AND TISSUE RESEARCH. 1985;239(1):69-74

ADULT HUMAN ARTERIAL SMOOTH-MUSCLE CELLS IN PRIMARY CULTURE - MODULATION FROM CONTRACTILE TO SYNTHETIC PHENOTYPE

THYBERG J; NILSSON J; PALMBERG L; SJOLUND M
Journal article: DIFFERENTIATION. 1984;27(2):158-162

PHENOTYPE MODULATION IN PRIMARY CULTURES OF ARTERIAL SMOOTH-MUSCLE CELLS - DUAL EFFECT OF PROSTAGLANDIN-E1

SJOLUND M; NILSSON J; PALMBERG L; THYBERG J
Journal article: HISTOCHEMISTRY. 1983;78(4):435-449

APPLICATION OF OPTICAL DIFFRACTOMETRY IN STUDIES OF CELL FINE-STRUCTURE - COMPARISON OF ARTERIAL SMOOTH-MUSCLE CELLS IN CONTRACTILE AND SYNTHETIC STATE

OSTROWSKI K; THYBERG J; DZIEDZICGOCLAWSKA A; ROZYCKA M; LENCZOWSKI S; KSIAZEK T; NILSSON J; PALMBERG L; SJOLUND M
Journal article: DIFFERENTIATION. 1983;25(2):156-167

PHENOTYPE MODULATION IN PRIMARY CULTURES OF ARTERIAL SMOOTH-MUSCLE CELLS - ON THE ROLE OF PLATELET-DERIVED GROWTH-FACTOR

THYBERG J; PALMBERG L; NILSSON J; KSIAZEK T; SJOLUND M
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Review: TOXICS. 2023;11(8):667

Heated Tobacco Products: Insights into Composition and Toxicity

Upadhyay S; Rahman M; Johanson G; Palmberg L; Ganguly K
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2023;207:a5707

Lipid Peroxidation and Ferroptosis as Candidate Pathways of Heated Tobacco Product Toxicity in the Lung

Ganguly K; Rahman M; Irmler M; Introna M; Beckers J; Palmberg L; Johanson G; Upadhyay S
Preprint: RESEARCH SQUARE. 2022

Lipid from electronic cigarette smoke both with and without nicotine induced pro- inflammatory macrophage polarization and disrupted phagocytosis

Rahman M; Sompa SI; Introna M; Upadhyay S; Ganguly K; Palmberg L
Preprint: RESEARCH SQUARE. 2022

Lipid from electronic cigarette smoke both with and without nicotine induced pro- inflammatory macrophage polarization and disrupted phagocytosis

Rahman M; Sompa SI; Introna M; Upadhyay S; Ganguly K; Palmberg L
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2022;60:2374

Predictors of electronic cigarette use and its association with respiratory health and obesity in young adulthood in Sweden

Sompa S; Zettergren A; Ekstrom S; Upadhyay S; Ganguly K; Georgelis A; Ljungman P; Pershagen G; Kull I; Melen E; Palmberg L; Bergstrom A
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2022;60:1771

Genome-wide exploration of inflammation-related proteins and Type 2 asthma

Hernandez-Pacheco N; Bjorkander S; Klevebro S; Merid SK; Kumar A; Mogensen I; Janson C; Palmberg L; Van Hage M; Georgellis A; Bergstrom A; Kull I; Melen E
Meeting abstract: EUROPEAN RESPIRATORY JOURNAL. 2022;60:3474

Potential toxic effects in the lung of planetary dust

Ji J; Corazzari I; Turci F; Gerde P; Karlsson L; Linnarsson D; Loftus DJ; Prisk GK; Staufer U; Tranfield EM; Westrenen WV; Palmberg L
Preprint: RESEARCH SQUARE. 2022

Comparable oxidative stress, inflammatory response, and impaired phagocytosis against biodiesel and diesel exhaust particles in advanced multicellular human lung mucosa models

Rahman M; Upadhyay S; Ganguly K; Introna M; Ji J; Boman C; Muala A; Blomberg A; Sandström T; Palmberg L
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2021;58:oa4053

Late Breaking Abstract - Lung function before and after COVID-19 infection in young adults

Mogensen I; Hallberg J; Bjorkander S; Pan-Hammarstrom Q; Palmberg L; Janson C; Bergstrom A; Melen E; Kull I
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2020;201:a2768

Flavor, Nicotine Content, Vaping Regime, and Lung Region Matter: Alarm Anti-Proteases and Anti-Microbial Defensins Are Important for Electronic Cigarette Related Pulmonary Response

Ganguly K; Thimraj TA; Nordstrom A; Ramstrom M; Lin E; O'Brien F; Koelmel J; Ernstgard L; Johanson G; Pollitt K; Palmberg L; Upadhyay S
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2020;201:a2889

Assessment of Biomass Smoke Induced Pulmonary Response and the Protective Effect of Magnolol Using Physiologically Relevant Normal- and Chronic Bronchitis-Like Bronchial Mucosa Models

Upadhyay S; Rinaldi S; Thimraj TA; Lin E; O'Brien F; Koelmel J; Ernstgard L; Johanson G; Mahesh P; Pollitt K; Palmberg L; Ganguly K
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2019;199:a2487

Homeostatic Chemokines May Play an Important Role in Biomass Smoke Induced Chronic Obstructive Pulmonary Disease Among Women

Ganguly K; Vishweswaraiah S; Thimraj TA; George L; Krishnarao CS; Lokesh KS; Siddaiah JB; Larsson K; Upadhyay S; Palmberg L; Anand MP
Conference publication: 2018;:pa4293

OSTEOPONTIN PROTECTS AGAINST LUNG INJURY CAUSED BY EXTRACELLULAR HISTONES

Kasetty G; Papareddy P; Bhongir RK; Ali M; Mori M; Wygrecka M; Erjefält JS; Palmberg L; Hultgardh A; Herwald H; Egesten A
Review: TOXICOLOGICAL SCIENCES. 2018;164(1):21-30

Air-Liquid Interface: Relevant In Vitro Models for Investigating Air Pollutant-Induced Pulmonary Toxicity

Upadhyay S; Palmberg L
Review: EUROPEAN RESPIRATORY REVIEW. 2018;27(147):170122

Cadmium in tobacco smokers: a neglected link to lung disease?

Ganguly K; Levanen B; Palmberg L; Akesson A; Linden A
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2016;193

Impact Of Tobacco Smoking On Extracellular Il-17a Protein In The Peripheral Airways

Levanen B; Glader P; Dahlen B; Billing B; Palmberg L; Qvarfordt I; Larsson K; Linden A
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2016;193

Cadmium In The Peripheral Airways Of Tobacco Smokers With And Without COPD

Levanen B; Sundblad B-M; Ji J; Midander K; Julander A; Che KF; Larsson K; Palmberg L; Linden A
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2016;193

Modulation Of Tlr3-Stimulated Release Of Il-26 By Il-17a And Il-22 In Bronchial Epithelial Cells

Che KF; Palmberg L; Linden A
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2015;46:pa5110

LSC Abstract - Interleukin-26 in antibacterial host defense of human lungs: Effects on neutrophil mobilization

Che KF; Tengvall S; Levanen B; Silverpil E; Smith M; Awad M; Vikstrom M; Palmberg L; Qvarfordt I; Skold M; Linden A
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2015;46:pa851

LATE-BREAKING ABSTRACT: Linoleic acid-derived lipid mediators increase in a female-dominated subphenotype of COPD

Balgoma D; Yang M; Sjodin M; Snowden S; Karimi R; Levanen B; Merikallio H; Kaarteenaho R; Palmberg L; Larsson K; Erle D; Dahlen S-E; Dahlen B; Skold M; Wheelock A; Wheelock C
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2015;191

Signaling Mechanisms And Release Of Il-26 In Human Structural Lung Cells In Response To Pathogen Associated Molecular Patterns

Che KF; Ji J; Palmberg L; Skold M; Linden A
Conference publication: ACS NATIONAL MEETING BOOK OF ABSTRACTS. 2014;248

Systems biology approaches reveal low-dose effects of dendrimers

Feliu N; Kohonen P; Palmberg L; Nystrom AM; Fadeel B
Conference publication: CANCER RESEARCH. 2013;73(8):5657

Polyamidoamine dendrimers induce epigenetic changes in cultured normal and malignant human lung epithelial cells.

Kohonen PJ; Feliu NT; Palmberg L; Karlsson HL; Wallberg AE; Grafstrom RC; Fadeel B
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2013;42

Local and systemic inflammation in chronic obstructive pulmonary disease (COPD)

Ji J; von Scheele I; Dahlen B; Bergstrom J; Billing B; Lantz A-S; Larsson K; Palmberg L
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2012;40

Reduction of particles by using a particle separator in pig barn environment reduces inflammatory response in healthy volunteers

Hedelin A; Sundblad B-M; Larsson K; Palmberg L
Conference publication: PROSTAGLANDINS & OTHER LIPID MEDIATORS. 2006;79(1-2):174

Prostaglandin D2 release from mast cells after anti-IgE and/or IL-1βstimulation

Gulliksson M; Palmberg L; Nilsson G; Kumlin M
Published conference paper: AMERICAN JOURNAL OF INDUSTRIAL MEDICINE. 2004;46(4):410-413

Working group report 1:: Tools for the diagnosis of organic dusts-induced disease

Wouters IM; Sigsgaard T; Góra A; Nowak D; Palmberg L; Sundblad BM; Tutluoglu B
Published conference paper: AMERICAN JOURNAL OF INDUSTRIAL MEDICINE. 2004;46(4):363-370

Partial protection by respirators on airways responses following exposure in a swine house

Palmberg L; Larsson BM; Sundblad BM; Larsson K
Corrigendum: RESPIRATORY MEDICINE. 2003;97(5):588

Effects by 8-bromo-cyclicAMP on basal and organic dust-induced release of interleukin-6 and -8 in A549 human airway epithelial cells (vol 97, pg 46, 2003)

Burvall K; Palmberg L; Larsson K
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2003;22:42S

De novo synthesis of IL-17 in human airways following exposure to organic dust

Ivanov S; Prause O; Palmberg L; Larsson K; Lindén A
Conference publication: JOURNAL OF STRUCTURAL BIOLOGY. 1985;91(3):259

PHENOTYPE MODULATION IN PRIMARY CULTURES OF ARTERIAL SMOOTH-MUSCLE CELLS - REORGANIZATION OF THE CYTOSKELETON AND FORMATION OF A SECRETORY APPARATUS

THYBERG J; PALMBERG L; SJOLUND M
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Forskningsbidrag

Cleaning agents and occupational airway disease: a translational perspective of mixture effects from in vitro to regulation

Swedish Research Council for Health Working Life and Welfare

1 January 2024 - 31 December 2026
Lung toxicity of particles derived from combustion of novel renewable fuels

Swedish Research Council for Environment Agricultural Sciences and Spatial Planning

1 January 2022 - 31 December 2025
Exploring immunologic and genetic factors in COVID-19 with relevance for respiratory disease; a new BAMSE follow-up

Swedish Heart-Lung Foundation

1 January 2021 - 31 December 2021
Stockholm Chronic Obstructive Lung Disease Inflammation Cohort (SCOPIC)

Swedish Heart-Lung Foundation

1 January 2021 - 31 December 2021
Molecular patho-mechanism of biomass smoke induced chronic obstructive pulmonary disease among women: Population based- and in vitro exposure studies

Swedish Heart-Lung Foundation

1 January 2021 - 31 December 2022
Understanding the role of lung microbiome in biomass smoke exposure related chronic obstructive pulmonary disease

Swedish Research Council

1 December 2020 - 31 December 2022
Molecular patho-mechanism of biomass smoke induced chronic obstructive pulmonary disease among women: Population based- and in vitro exposure studies

Swedish Heart-Lung Foundation

1 January 2019 - 31 December 2020
E-cigarettrökning ett potentiellt hälsohot särskilt bland unga.

Swedish Heart-Lung Foundation

1 January 2019 - 31 December 2021
Metallic nanoparticle – cell interactions from an inhalation toxicity perspective

Swedish Research Council

1 January 2018 - 31 December 2021
Development of multi-cellular lung mucosa models for air pollutant mediated toxicity testing and assessing treatment strategies for chronic obstructive pulmonary disease (COPD) and chronic bronchitis

Swedish Research Council

1 January 2018 - 31 December 2021
Interleukin-26 och andra Th17-cytokiner i humana lungors medfödda immunitet

Swedish Research Council

1 January 2017 - 31 December 2020
New systems for exposing human 3D-models of airway mucosa in health and disease to particulate- and gaseous air pollutants

Swedish Research Council

1 January 2015 - 31 December 2017
Molecular precursors and molecular models of nanoporous materials

Swedish Research Council

1 January 2012 - 31 December 2014
Reducing the use of laboratory animals by combining an in vitro model of the airway wall based on primary human cells with controlled nanoparticle aerosol exposures.

Swedish Research Council

1 January 2011 - 31 December 2013

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