Laszlo Szekely

Publikationer
Forskningsbidrag
CV
Populärvetenskap och samverkan

Artiklar

Journal article: JOURNAL OF MEDICAL CASE REPORTS. 2023;17(1):529
The D ∼ Sense ex-vivo viability assay application in a patient with stage IV lung adenocarcinoma: a case report
Zhang Y; Wu X; He P; Wu J; Gu X; Bendek M; Otvos R; Szekely L
Article: SCANDINAVIAN CARDIOVASCULAR JOURNAL. 2022;56(1):166-173
Morphological changes without histological myocarditis in hearts of COVID-19 deceased patients
Razaghi A; Szakos A; Al-Shakarji R; Bjornstedt M; Szekely L
Article: BMC BIOINFORMATICS. 2022;23(1):546
AtlasGrabber: a software facilitating the high throughput analysis of the human protein atlas online database
Bozoky B; Szekely L; Ernberg I; Savchenko A
Article: NATURE METABOLISM. 2022;4(12):1674-1683
COVID-19 instigates adipose browning and atrophy through VEGF in small mammals
Jing X; Wu J; Dong C; Gao J; Seki T; Kim C; Urgard E; Hosaka K; Yang Y; Long S; Huang P; Zheng J; Szekely L; Zhang Y; Tao W; Coquet J; Ge M; Chen Y; Adner M; Cao Y
Article: DIAGNOSTICS. 2022;12(11):2789
Proteomic Analysis of Pleural Effusions from COVID-19 Deceased Patients: Enhanced Inflammatory Markers
Razaghi A; Szakos A; Alouda M; Bozoky B; Bjornstedt M; Szekely L
Article: NEOPLASIA: AN INTERNATIONAL JOURNAL FOR ONCOLOGY RESEARCH. 2021;23(12):1300-1306
Stabilization of the classical phenotype upon integration of pancreatic cancer cells into the duodenal epithelium
Bozoky B; Moro CF; Strell C; Geyer N; Heuchel RL; Lohr JM; Ernberg I; Szekely L; Gerling M; Bozoky B
Article: CELL REPORTS. 2021;37(4):109892
Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CL^pro substrate degradome
Pablos I; Machado Y; de Jesus HCR; Mohamud Y; Kappelhoff R; Lindskog C; Vlok M; Bell PA; Butler GS; Grin PM; Cao QT; Nguyen JP; Solis N; Abbina S; Rut W; Vederas JC; Szekely L; Szakos A; Drag M; Kizhakkedathu JN; Mossman K; Hirota JA; Jan E; Luo H; Banerjee A; Overall CM
Article: MALARIA JOURNAL. 2021;20(1):303
Direct contact between Plasmodium falciparum and human B-cells in a novel co-culture increases parasite growth and affects B-cell growth
Reddy SB; Nagy N; Ronnberg C; Chiodi F; Lugaajju A; Heuts F; Szekely L; Wahlgren M; Persson KEM
Article: ISCIENCE. 2021;24(5):102420
Cell-type-resolved quantitative proteomics map of interferon response against SARS-CoV-2
Saccon E; Chen X; Mikaeloff F; Rodriguez JE; Szekely L; Vinhas BS; Krishnan S; Byrareddy SN; Frisan T; Vegvari A; Mirazimi A; Neogi U; Gupta S
Article: HELIYON. 2021;7(5):e07134
Pulmonary stromal expansion and intra-alveolar coagulation are primary causes of COVID-19 death
Szekely L; Bozoky B; Bendek M; Ostad M; Lavignasse P; Haag L; Wu J; Jing X; Gupta S; Saccon E; Sonnerberg A; Cao Y; Bjornstedt M; Szakos A
Article: ONCOGENESIS. 2018;7(11):84
Aberrant ARID5B expression and its association with Ikaros dysfunction in acute lymphoblastic leukemia
Ge Z; Han Q; Gu Y; Ge Q; Ma J; Sloane J; Gao G; Payne KJ; Szekely L; Song C; Dovat S
Article: GASTROENTEROLOGY RESEARCH AND PRACTICE. 2018;2018:7345426-7
Diminished DEFA6 Expression in Paneth Cells Is Associated with Necrotizing Enterocolitis
Markasz L; Wanders A; Szekely L; Lilja HE
Article: SCIENTIFIC REPORTS. 2018;8(1):11014
Cellular-resolution 3D virtual histology of human coronary arteries using x-ray phase tomography
Vagberg W; Persson J; Szekely L; Hertz HM
Article: EXPERIMENTAL HEMATOLOGY. 2016;44(1):38-49.e1
Sensitivity of chronic lymphocytic leukemia cells to small targeted therapeutic molecules: An in vitro comparative study
Sylvan SE; Skribek H; Norin S; Muhari O; Osterborg A; Szekely L
Article: JOURNAL OF EXPERIMENTAL AND CLINICAL CANCER RESEARCH. 2015;34(1):62
Confrontation of fibroblasts with cancer cells in vitro: gene network analysis of transcriptome changes and differential capacity to inhibit tumor growth
Alexeyenko A; Alkasalias T; Pavlova T; Szekely L; Kashuba V; Rundqvist H; Wiklund P; Egevad L; Csermely P; Korcsmaros T; Guven H; Klein G
Article: GENES AND CANCER. 2015;6(3-4):119-128
Drug sensitivity profiling and molecular characteristics of cells from pleural effusions of patients with lung adenocarcinoma.
Ötvös R; Szulkin A; Hillerdal C-O; Celep A; Yousef-Fadhel E; Skribek H; Hjerpe A; Székely L; Dobra K
Article: CELLULAR SIGNALLING. 2015;27(2):363-372
Inhibition of protein phosphatase-1 and -2A decreases the chemosensitivity of leukemic cells to chemotherapeutic drugs
Dedinszki D; Kiss A; Markasz L; Marton A; Toth E; Szekely L; Erdodi F
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2014;111(48):17188-17193
Inhibition of tumor cell proliferation and motility by fibroblasts is both contact and soluble factor dependent
Alkasalias T; Flaberg E; Kashuba V; Alexeyenko A; Pavlova T; Savchenko A; Szekely L; Klein G; Guven H
Article: BMC CANCER. 2014;14:709
Characterization and drug sensitivity profiling of primary malignant mesothelioma cells from pleural effusions
Szulkin A; Otvos R; Hillerdal C-O; Celep A; Yousef-Fadhel E; Skribek H; Hjerpe A; Szekely L; Dobra K
Article: CANCER MEDICINE. 2014;3(3):485-491
Decreased decorin expression in the tumor microenvironment
Bozoky B; Savchenko A; Guven H; Ponten F; Klein G; Szekely L
Article: ANTICANCER RESEARCH. 2014;34(2):893-898
Molecular Typing of Human Herpesvirus 8 Isolates from Patients with Kaposi's Sarcoma in Hungary
Oetvoes R; Juhasz A; Szalai E; Ujvari D; Oetvoes K; Szabo K; Remenyik E; Szekely L; Gergely L; Konya J
Article: INTERNATIONAL JOURNAL OF CANCER. 2013;133(2):286-293
Novel signatures of cancer-associated fibroblasts
Bozoky B; Savchenko A; Csermely P; Korcsmaros T; Dul Z; Ponten F; Szekely L; Klein G
Article: PLOS ONE. 2013;8(7):e69781
Improved In Vitro Culture of Plasmodium falciparum Permits Establishment of Clinical Isolates with Preserved Multiplication, Invasion and Rosetting Phenotypes
Ribacke U; Moll K; Albrecht L; Ismail HA; Normark J; Flaberg E; Szekely L; Hultenby K; Persson KEM; Egwang TG; Wahlgren M
Article: INTERNATIONAL JOURNAL OF CANCER. 2012;131(10):2274-2283
The architecture of fibroblast monolayers of different origin differentially influences tumor cell growth
Flaberg E; Guven H; Savchenko A; Pavlova T; Kashuba V; Szekely L; Klein G
Article: APMIS. 2012;120(10):786-793
Protective immunization against Staphylococcus aureus infection in a novel experimental wound model in mice
Schennings T; Farnebo F; Szekely L; Flock J-I
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2012;109(33):13231-13236
Control of cyclooxygenase-2 expression and tumorigenesis by endogenous 5-methoxytryptophan
Cheng H-H; Kuo C-C; Yan J-L; Chen H-L; Lin W-C; Wang K-H; Tsai KK-C; Guven H; Flaberg E; Szekely L; Klein G; Wu KK
Article: BREAST CANCER RESEARCH. 2012;14(4):R114
High-throughput mammographic-density measurement: a tool for risk prediction of breast cancer
Li J; Szekely L; Eriksson L; Heddson B; Sundbom A; Czene K; Hall P; Humphreys K
Journal article: PLOS ONE. 2012;7(7):10.1371/annotation/3ac2b8
Correction: Symbionts as Major Modulators of Insect Health: Lactic Acid Bacteria and Honeybees
VÃ¡squez A; Forsgren E; Fries I; Paxton RJ; Flaberg E; Szekely L; Olofsson TC
Article: THE FASEB JOURNAL. 2012;26(6):2374-2382
Rho GTPases link cellular contractile force to the density and distribution of nanoscale adhesions
Gad AKB; Ronnlund D; Spaar A; Savchenko AA; Petranyi G; Blom H; Szekely L; Widengren J; Aspenstrom P
Article: PLOS ONE. 2012;7(3):e33188
Symbionts as Major Modulators of Insect Health: Lactic Acid Bacteria and Honeybees
Vasquez A; Forsgren E; Fries I; Paxton RJ; Flaberg E; Szekely L; Olofsson TC
Article: BMC CANCER. 2011;11:441
Drug sensitivity patterns of HHV8 carrying body cavity lymphoma cell lines
Otvos R; Skribek H; Kis LL; Gloghini A; Markasz L; Flaberg E; Eksborg S; Konya J; Gergely L; Carbone A; Szekely L
Article: CELL CYCLE. 2011;10(19):3346-3358
Pharmacological activation of p53 triggers anticancer innate immune response through induction of ULBP2
Li H; Lakshmikanth T; Garofalo C; Enge M; Spinnler C; Anichini A; Szekely L; Karre K; Carbone E; Selivanova G
Article: INTERNATIONAL JOURNAL OF CANCER. 2011;128(12):2793-2802
High-throughput live-cell imaging reveals differential inhibition of tumor cell proliferation by human fibroblasts
Flaberg E; Markasz L; Petranyi G; Stuber G; Dicso F; Alchihabi N; Olah E; Csizy I; Jozsa T; Andren O; Johansson J-E; Andersson S-O; Klein G; Szekely L
Article: INTERNATIONAL JOURNAL OF CANCER. 2011;128(4):817-825
Epstein-Barr virus-encoded EBNA-5 forms trimolecular protein complexes with MDM2 and p53 and inhibits the transactivating function of p53
Kashuba E; Yurchenko M; Yenamandra SP; Snopok B; Szekely L; Bercovich B; Ciechanover A; Klein G
Article: EXPERIMENTAL HEMATOLOGY. 2010;38(12):1219-1230
Chronic lymphoid leukemia cells are highly sensitive to the combination of prednisolone and daunorubicin, but much less to doxorubicin or epirubicin
Skribek H; Otvos R; Flaberg E; Nagy N; Markasz L; Eksborg S; Masszi T; Kozma A; Adam E; Miseta A; Klein E; Szekely L
Article: CANCER RESEARCH. 2010;70(8):3372-3381
Rescue of p53 Function by Small-Molecule RITA in Cervical Carcinoma by Blocking E6-Mediated Degradation
Zhao CY; Szekely L; Bao W; Selivanova G
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2009;47(11):1661-1671
High levels of thioredoxin reductase 1 modulate drug-specific cytotoxic efficacy
Eriksson SE; Prast-Nielsen S; Flaberg E; Szekely L; Arner ESJ
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009;106(47):19866-19871
MRPS18-2 protein immortalizes primary rat embryonic fibroblasts and endows them with stem cell-like properties
Kashuba E; Yenamandra SP; Darekar SD; Yurchenko M; Kashuba V; Klein G; Szekely L
Article: BIOMEDICINE & PHARMACOTHERAPY. 2009;63(6):413-420
NK cell-mediated lysis is essential to kill Epstein-Barr virus transformed lymphoblastoid B cells when using rituximab
Markasz L; Vanherberghen B; Flaberg E; Otvos R; Stuber G; Jernberg AG; Olah E; Skribek H; Szekely L
Article: MOLECULAR CANCER. 2009;8:23
PRIMA-1^MET induces nucleolar translocation of Epstein-Barr virus-encoded EBNA-5 protein
Stuber G; Flaberg E; Petranyi G; Otvos R; Rokaeus N; Kashuba E; Wiman KG; Klein G; Szekely L
Article: EXPERIMENTAL ONCOLOGY. 2008;30(4):327-329
Immunofluorescence staining of paraffin sections: creating DAB staining like virtual digital images using CMYK color conversion.
Buchynska L; Kashuba E; Szekely L
Article: BMC MEDICAL IMAGING. 2008;8:13
Extended Field Laser Confocal Microscopy (EFLCM): combining automated Gigapixel image capture with in silico virtual microscopy.
Flaberg E; Sabelström P; Strandh C; Szekely L
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2008;105(14):5489-5494
EBV-encoded EBNA-6 binds and targets MRS18-2 to the nucleus, resulting in the disruption of pRb-E2F1 complexes
Kashuba E; Yurchenko M; Yenamandra SP; Snopok B; Isaguliants M; Szekely L; Klein G
Article: JOURNAL OF IMMUNOTHERAPY. 2008;31(3):283-293
Effect of frequently used chemotherapeutic drugs on cytotoxic activity of human cytotoxic T-lymphocytes
Markasz L; Skribek H; Uhlin M; Otvos R; Flaberg E; Eksborg S; Olah E; Stuber G; Szekely L
Article: LEUKEMIA AND LYMPHOMA. 2007;48(9):1835-1845
Hodgkin-lymphoma-derived cells show high sensitivity to dactinomycin and paclitaxel
Markasz L; Kis LL; Stuber G; Flaberg E; Otvos R; Eksborg S; Skribek H; Olah E; Szekely L
Article: MOLECULAR CANCER. 2007;6:28
HHV-8 encoded LANA-I alters the higher organization of the cell nucleus
Stuber G; Mattsson K; Flaberg E; Kati E; Markasz L; Sheldon JA; Klein G; Schulz TF; Szekely L
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2007;104(10):3919-3924
Filamin B deficiency in mice results in skeletal malformations and impaired microvascular development
Zhou X; Tian F; Sandzen J; Cao R; Flaberg E; Szekely L; Cao Y; Ohlsson C; Bergo MO; Boren J; Akyurek LM
Article: ONCOGENE. 2007;26(7):982-992
PRIMA-1^MET induces nucleolar accumulation of mutant p53 and PML nuclear body-associated proteins
Rokaeus N; Klein G; Wiman KG; Szekely L; Mattsson K
Article: MOLECULAR CANCER THERAPEUTICS. 2007;6(2):644-654
Effect of frequently used chemotherapeutic drugs on the cytotoxic activity of human natural killer cells
Markasz L; Stuber G; Vanherberghen B; Flaberg E; Olah E; Carbone E; Eksborg S; Klein E; Skribek H; Szekely L
Article: ANALYTICAL AND BIOANALYTICAL CHEMISTRY. 2006;386(7-8):2063-2073
SPR-based immunocapture approach to creating an interfacial sensing architecture: mapping of the MRS18-2 binding site on retinoblastoma protein
Snopok B; Yurchenko M; Szekely L; Klein G; Kashuba E
Article: BMC CANCER. 2006;6:265
Cytotoxic drug sensitivity of Epstein-Barr virus transformed lymphoblastoid B-cells
Markasz L; Stuber G; Flaberg E; Jernberg AG; Eksborg S; Olah E; Skribek H; Szekely L
Article: ACTA HISTOCHEMICA ET CYTOCHEMICA. 2006;39(4):103-106
Multi-dimensional laser confocal microscopy on live cells in submicroliter volumes using glass capillaries
Flaberg E; Stuber G; Szekely L
Article: GENES CHROMOSOMES AND CANCER. 2006;45(5):470-481
Molecular classification of mucoepidermoid carcinomas -: Prognostic significance of the MECT1-MAML2 fusion oncogene
Behboudi A; Enlund F; Winnes M; Andrén Y; Nordkvist A; Leivo I; Flaberg E; Szekely L; Mäkitie A; Grenman R; Mark J; Stenman G
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2006;281(2):1215-1223
Regulation of transactivation function of the aryl hydrocarbon receptor by the Epstein-Barr virus-encoded EBNA-3 protein
Kashuba EV; Gradin K; Isaguliants M; Szekely L; Poellinger L; Klein G; Kazlauskas A
Article: EXPERIMENTAL CELL RESEARCH. 2005;303(1):47-55
Epstein-Barr virus-encoded EBNA-5 binds to Epstein-Barr virus-induced Fte1/S3a protein
Kashuba E; Yurchenko M; Szirak K; Stahl J; Klein G; Szekely L
Article: INTERNATIONAL JOURNAL OF CANCER. 2003;107(4):597-602
Upregulation of the truncated basic hair keratin 1(hHb1-ΔN) in carcinoma cells by Epstein-Barr virus (EBV)
Nishikawa J; Kiss C; Imai S; Takada K; Okita K; Klein G; Szekely L
Article: INTERNATIONAL JOURNAL OF CANCER. 2003;105(5):644-653
EBV-encoded EBNA-5 associates with P14ARF in extranucleolar inclusions and prolongs the survival of P14ARF-expressing cells
Kashuba E; Mattsson K; Pokrovskaja K; Kiss C; Protopopova M; Ehlin-Henriksson B; Klein G; Szekely L
Article: JOURNAL OF VIROLOGY. 2003;77(12):7093-7100
A domain in the C-terminal region of latency-associated nuclear antigen 1 of Kaposi's sarcoma-associated herpesvirus affects transcriptional activation and binding to nuclear heterochromatin
Viejo-Borbolla A; Kati E; Sheldon JA; Nathan K; Mattsson K; Szekely L; Schulz TF
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2003;100(8):4813-4818
T cell leukemia 1 oncogene expression depends on the presence of Epstein-Barr virus in the virus-carrying Burkitt lymphoma lines
Kiss C; Nishikawa J; Takada K; Trivedi P; Klein G; Szekely L
Article: BMC MICROBIOLOGY. 2003;3:6
Ebola virus infection inversely correlates with the overall expression levels of promyelocytic leukaemia (PML) protein in cultured cells -: art. no. 6
Björndal AS; Szekely L; Elgh F
Article: MOLECULAR CANCER. 2003;2:18
p14ARF induces the relocation of HDM2 and p53 to extranucleolar sites that are targeted by PML bodies and proteasomes.
Kashuba E; Mattsson K; Klein G; Szekely L
Article: JOURNAL OF VIROLOGICAL METHODS. 2003;107(2):195-203
Improved subtractive suppression hybridization combined with high density cDNA array screening identifies differentially expressed viral and cellular genes
Kiss C; Nishikawa J; Dieckmann A; Takada K; Klein G; Szekely L
Article: BMC CELL BIOLOGY. 2002;3:23
Epstein-Barr virus encoded nuclear protein EBNA-3 binds a novel human uridine kinase/uracil phosphoribosyltransferase
Kashuba E; Kashuba V; Sandalova T; Klein G; Szekely L
Article: INTERNATIONAL JOURNAL OF CANCER. 2002;99(5):705-712
CD40 ligation downregulates EBNA-2 and LMP-1 expression in EBV-transformed lymphoblastoid cell lines
Pokrovskaja K; Ehlin-Henriksson B; Kiss C; Challa A; Gordon J; Gogolak P; Klein G; Szekely L
Article: NEW BIOTECHNOLOGY. 2002;19(1):31-34
Optimisation of the degenerate oligonucleotide primed PCR (DOP-PCR) for capillary thermocycler
Kiss C; Kost-Alimova M; Klein G; Szekely L
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2002;277(19):17009-17015
Identification of ERp29, an endoplasmic reticulum lumenal protein, as a new member of the thyroglobulin folding complex
Sargsyan E; Baryshev M; Szekely L; Sharipo A; Mkrtchian S
Article: JOURNAL OF GENERAL VIROLOGY. 2002;83(Pt 1):179-188
Latent nuclear antigen of Kaposi's sarcoma herpesvirus/human herpesvirus-8 induces and relocates RING3 to nuclear heterochromatin regions
Mattsson K; Kiss C; Platt GM; Simpson GR; Kashuba E; Klein G; Schulz TF; Szekely L
Article: VIROLOGY. 2001;288(2):275-282
Intranuclear localization of the transcription coadaptor CBP/p300 and the transcription factor RBP-Jk in relation to EBNA-2 and-5 in B lymphocytes
Bandobashi K; Maeda A; Teramoto N; Nagy N; Székely L; Taguchi H; Miyoshi I; Klein G; Klein E
Article: JOURNAL OF HUMAN VIROLOGY. 2001;4(5):227-237
Epstein-Barr virus can infect B-chronic lymphocytic leukemia cells but it does not orchestrate the cell cycle regulatory proteins
Maeda A; Bandobashi K; Nagy N; Teramoto N; Gogolák P; Pokrovskaja K; Székely L; Björkholm M; Klein G; Klein E
Article: INTERNATIONAL JOURNAL OF CANCER. 2001;93(5):714-719
EBNA promoter usage in EBV-negative Burkitt lymphoma cell lines converted with a neomycin-resistant EBV strain
Maeda A; Kiss C; Chen F; Ehlin-Henriksson B; Nagy N; Szekely L; Takada K; Klein E; Klein G
Article: JOURNAL OF GENERAL VIROLOGY. 2001;82(Pt 2):345-358
Proteasome inhibitor induces nucleolar translocation of Epstein-Barr virus-encoded EBNA-5
Pokrovskaja K; Mattsson K; Kashuba E; Klein G; Szekely L
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2001;98(3):1012-1017
Proteins associated with the promyelocytic leukemia gene product (PML)-containing nuclear body move to the nucleolus upon inhibition of proteasome-dependent protein degradation
Mattsson K; Pokrovskaja K; Kiss C; Klein G; Szekely L
Article: BRITISH JOURNAL OF CANCER. 2001;84(1):122-125
A prospective seroepidemiological study of human herpesvirus-8 infection and the risk of multiple myeloma
Tedeschi R; Kvarnung M; Knekt P; Schulz TF; Szekely L; De Paoli P; Aromaa A; Teppo L; Dillner J
Article: INTERNATIONAL JOURNAL OF CANCER. 2000;88(3):439-447
SH2D1A and SLAM protein expression in human lymphocytes and derived cell lines
Nagy N; Cerboni C; Mattsson K; Maeda A; Gogolák P; Sümegi J; Lányi A; Székely L; Carbone E; Klein G; Klein E
Article: ONCOGENE. 2000;19(14):1801-1806
Epstein-Barr virus encoded nuclear protein EBNA-3 binds XAP-2, a protein associated with Hepatitis B virus X antigen
Kashuba E; Kashuba V; Pokrovskaja K; Klein G; Szekely L
Article: JOURNAL OF GENERAL VIROLOGY. 1999;80:2889-2900
Human herpesvirus-8-encoded LNA-1 accumulates in heterochromatin-associated nuclear bodies
Szekely L; Kiss C; Mattsson K; Kashuba E; Pokrovskaja K; Juhasz A; Holmvall P; Klein G
Article: APPLIED IMMUNOHISTOCHEMISTRY AND MOLECULAR MORPHOLOGY. 1999;7(3):226-236
Computer programs that allow fast acquisition, visualization and overlap quantitation of fluorescent 3D microscopic objects by using nearest-neighbor deconvolution algorithm
Holmvall P; Szekely L
Journal article: APPLIED IMMUNOHISTOCHEMISTRY AND MOLECULAR MORPHOLOGY. 1999;7(3):226
Computer Programs That Allow Fast Acquisition, Visualization and Overlap Quantitation of Fluorescent 3D Microscopic Objects by Using Nearest-Neighbor Deconvolution Algorithm
Holmvall P; Szekely L
Article: INTERNATIONAL JOURNAL OF CANCER. 1999;81(4):543-550
Expression of cyclin D2 and D3 in lymphoid lesions
Teramoto N; Pokrovskaja K; Szekely L; Polack A; Yoshino T; Akagi T; Klein G
Article: JOURNAL OF GENERAL VIROLOGY. 1999;80:987-995
Epstein-Barr virus infection and mitogen stimulation of normal B cells induces wild-type p53 without subsequent growth arrest or apoptosis
Pokrovskaja K; Okan I; Kashuba E; Löwbeer M; Klein G; Szekely L
Article: JOURNAL OF HUMAN VIROLOGY. 1999;2(1):33-37
Epstein-Barr virus-encoded nuclear protein EBNA-3 interacts with the ε-subunit of the T-complex protein 1 chaperonin complex
Kashuba E; Pokrovskaja K; Klein G; Szekely L
Article: JOURNAL OF HUMAN VIROLOGY. 1998;1(5):307-313
Differential expression and localization of EBER-1 and EBER-2 in Epstein-Barr virus-carrying cells.
Teramoto N; Szekely L; Klein G
Article: JOURNAL OF VIROLOGICAL METHODS. 1998;73(1):89-97
Simultaneous detection of two independent antigens by double staining with two mouse monoclonal antibodies
Teramoto N; Szekely L; Pokrovskaja K; Hu LF; Yoshino T; Akagi T; Klein G
Article: JOURNAL OF GENERAL VIROLOGY. 1998;79:1445-1452
Restricted expression of Epstein-Barr virus (EBV)-encoded, growth transformation-associated antigens in an EBV- and human herpesvirus type 8-carrying body cavity lymphoma line
Szekely L; Chen F; Teramoto N; Ehlin-Henriksson B; Pokrovskaja K; Szeles A; Manneborg-Sandlund A; Löwbeer M; Lennette ET; Klein G
Article: JOURNAL OF VIROLOGY. 1998;72(4):2969-2974
Specific methylation patterns in two control regions of Epstein-Barr virus latency: the LMP-1-coding upstream regulatory region and an origin of DNA replication (oriP)
Falk KI; Szekely L; Aleman A; Ernberg I
Article: MOLECULAR AND CELLULAR BIOLOGY. 1998;18(2):1084-1093
The promyelocytic leukemia gene product (PML) forms stable complexes with the retinoblastoma protein
Alcalay M; Tomassoni L; Colombo E; Stoldt S; Grignani F; Fagioli M; Szekely L; Helin K; Pelicci PG
Article: TRENDS IN MICROBIOLOGY. 1997;5(11):424-425
Multiple myeloma and Kaposi's sarcoma-associated herpesvirus - a paracrine model of tumorigenesis?
Szekely L; Klein G
Article: JOURNAL OF GENERAL VIROLOGY. 1997;78:2031-2040
Epstein-Barr virus-encoded LMP1 protein upregulates the pNDCF group of nucleoskeleton-cytoskeleton-associated proteins
Pokrovskaja K; Trivedi P; Klein G; Szekely L
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1997;45(6):678-682
Conversion of in vitro cultured human monocytes into effective presenters of an HER2/neu-encoded CTL peptide epitope
Wasserman K; Corsi MM; Szekely L; Kono K; Maes HH; Kiessling R
Article: EXPERIMENTAL CELL RESEARCH. 1997;233(1):25-32
Endogenous fibronectin of blood polymorphonuclear leukocytes: Immunochemical characterization and subcellular localization
Salcedo R; Segura C; Szekely L; deMesquita R; Biberfeld P; Patarroyo M
Article: MOLECULAR CANCER RESEARCH. 1997;8(5):599-609
Differential expression of nucleoskeleton- and cytoskeleton-associated proteins in Burkitt lymphoma-derived and Epstein-Barr virus-immortalized lymphoblastoid cell lines
Szekely L; Pokrovskaja K; Klein G
Article: MOLECULAR CANCER RESEARCH. 1996;7(12):1723-1732
Phenotype-related differences in the expression of D-type cyclins in human B cell-derived lines
Pokrovskaja K; EhlinHenriksson B; Bartkova J; Bartek J; Scuderi R; Szekely L; Wiman KG; Klein G
Article: JOURNAL OF VIROLOGY. 1996;70(4):2562-2568
The Epstein-Barr virus-encoded nuclear antigen EBNA-5 accumulates in PML-containing bodies
Szekely L; Pokrovskaja K; Jiang WQ; deThe H; Ringertz N; Klein G
Article: JOURNAL OF GENERAL VIROLOGY. 1995;76:2423-2432
REVERSIBLE NUCLEOLAR TRANSLOCATION OF EPSTEIN-BARR VIRUS-ENCODED EBNA-5 AND HSP70 PROTEINS AFTER EXPOSURE TO HEAT-SHOCK OR CELL-DENSITY CONGESTION
SZEKELY L; JIANG WQ; POKROVSKAJA K; WIMAN KG; KLEIN G; RINGERTZ N
Article: MOLECULAR CANCER RESEARCH. 1995;6(9):1071-1075
BCL-2 INHIBITS WILD-TYPE P53-TRIGGERED APOPTOSIS BUT NOT G(1) CELL-CYCLE ARREST AND TRANSACTIVATION OF WAF1 AND BAX
WANG YS; OKAN I; SZEKELY L; KLEIN G; WIMAN KG
Article: INTERNATIONAL JOURNAL OF CANCER. 1995;61(5):683-691
RB-RECONSTITUTED HUMAN RETINOBLASTOMA CELLS FORM RB-POSITIVE INTRAOCULAR AND INTRACEREBRAL BUT NOT SUBCUTANEOUS TUMORS IN SCID MICE
SZEKELY L; WANG YS; KLEIN G; WIMAN KG
Article: INTERNATIONAL IMMUNOLOGY. 1995;7(4):653-663
HLA-A0201 AND HLA-B7 BINDING PEPTIDES IN THE EBV-ENCODED EBNA-1, EBNA-2 AND BZLF-1 PROTEINS DETECTED IN THE MHC CLASS-I STABILIZATION ASSAY - LOW PROPORTION OF BINDING MOTIFS FOR SEVERAL HLA CLASS-I ALLELES IN EBNA-1
STUBER G; DILLNER J; MODROW S; WOLF H; SZEKELY L; KLEIN G; KLEIN E
Article: NUCLEIC ACIDS RESEARCH (NAR). 1995;23(3):362-369
P53 BINDS SINGLE-STRANDED-DNA ENDS THROUGH THE C-TERMINAL DOMAIN AND INTERNAL DNA SEGMENTS VIA THE MIDDLE DOMAIN
BAKALKIN G; SELIVANOVA G; YAKOVLEVA T; KISELEVA E; KASHUBA E; MAGNUSSON KP; SZEKELY L; KLEIN G; TERENIUS L; WIMAN KG
Journal article: INTERNATIONAL JOURNAL OF CANCER. 1994;58(5):663-667
MOLECULAR ANALYSIS OF THE RETINOBLASTOMA GENE IN PRIMARY OVARIAN-CANCER CELLS
LIU Y; HEYMAN M; WANG YS; FALKMER U; HISING C; SZEKELY L; EINHORN S
Journal article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1994;24(3):765-768
IDENTIFICATION OF WILD-TYPE AND MUTANT P53 PEPTIDES BINDING TO HLA-A2 ASSESSED BY A PEPTIDE LOADING-DEFICIENT CELL-LINE ASSAY AND A NOVEL MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-I PEPTIDE BINDING ASSAY
STUBER G; LEDER GH; STORKUS WJ; LOTZE MT; MODROW S; SZEKELY L; WOLF H; KLEIN E; KARRE K; KLEIN G
Journal article: ONCOGENE. 1994;9(3):809-818
CONTRASTING PATTERNS OF RETINOBLASTOMA PROTEIN EXPRESSION IN MOUSE EMBRYONIC STEM-CELLS AND EMBRYONIC FIBROBLASTS
SAVATIER P; HUANG S; SZEKELY L; WIMAN KG; SAMARUT J
Journal article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1994;91(1):413-417
P53 BINDS SINGLE-STRANDED-DNA ENDS AND CATALYZES DNA RENATURATION AND STRAND TRANSFER
BAKALKIN G; YAKOVLEVA T; SELIVANOVA G; MAGNUSSON KP; SZEKELY L; KISELEVA E; KLEIN G; TERENIUS L; WIMAN KG
Journal article: ONCOGENE. 1993;8(12):3427-3431
WILD-TYPE P53-TRIGGERED APOPTOSIS IS INHIBITED BY BCL-2 IN A V-MYC-INDUCED T-CELL LYMPHOMA LINE
WANG YS; SZEKELY L; OKAN I; KLEIN G; WIMAN KG
Journal article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1993;90(18):8697-8701
CHRONIC LYMPHOCYTIC-LEUKEMIA CELLS WITH ALLELIC DELETIONS AT 13Q14 COMMONLY HAVE ONE INTACT RB1 GENE - EVIDENCE FOR A ROLE OF AN ADJACENT LOCUS
LIU Y; SZEKELY L; GRANDER D; SODERHALL S; JULIUSSON G; GAHRTON G; LINDER S; EINHORN S
Journal article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1993;90(12):5455-5459
EBNA-5, AN EPSTEIN-BARR VIRUS-ENCODED NUCLEAR ANTIGEN, BINDS TO THE RETINOBLASTOMA AND P53 PROTEINS
SZEKELY L; SELIVANOVA G; MAGNUSSON KP; KLEIN G; WIMAN KG
Journal article: ONCOGENE. 1993;8(6):1495-1500
WILD-TYPE P53 INDUCED APOPTOSIS IN A BURKITT-LYMPHOMA (BL) LINE THAT CARRIES MUTANT P53
RAMQVIST T; MAGNUSSON KP; WANG YS; SZEKELY L; KLEIN G; WIMAN KG
Journal article: MOLECULAR CANCER RESEARCH. 1993;4(6):467-473
RECONSTITUTION OF WILD-TYPE P53 EXPRESSION TRIGGERS APOPTOSIS IN A P53-NEGATIVE V-MYC RETROVIRUS-INDUCED T-CELL LYMPHOMA LINE
WANG YS; RAMQVIST T; SZEKELY L; AXELSON H; KLEIN G; WIMAN KG
Journal article: JOURNAL OF CELLULAR PHYSIOLOGY. 1993;155(2):313-322
POSITION-DEPENDENT NUCLEAR ACCUMULATION OF THE RETINOBLASTOMA (RB) PROTEIN DURING INVITRO MYOGENESIS
SZEKELY L; JIN P; JIANG WQ; ROSEN A; WIMAN KG; KLEIN G; RINGERTZ N
Journal article: MOLECULAR CANCER RESEARCH. 1992;3(3):149-156
CELL TYPE AND DIFFERENTIATION DEPENDENT HETEROGENEITY IN RETINOBLASTOMA PROTEIN EXPRESSION IN SCID MOUSE FETUSES
SZEKELY L; JIANG WQ; BULICJAKUS F; ROSEN A; RINGERTZ N; KLEIN G; WIMAN KG
Journal article: BIOMEDICINE & PHARMACOTHERAPY. 1992;46(5-7):257
39. Involvement of the retinoblastoma (Rb) protein in the regulation of ceil differentiation
Szekely L; Jiang W; Savatier P; Bulic-Jakus F; Wendel-Hansen V; Rosen A; Ringertz N; Klein G; Wiman K
Journal article: BIOLOGY OF THE CELL. 1992;76(2):215
Absence of detectable RB protein in mouse embryonic stem (ES) cells contributes to E1A‐like activity
Huang S; Savatier P; Szekely L; Wiman KG; Samarut J
Journal article: EXPERIMENTAL CELL RESEARCH. 1991;197(2):314-318
COLOCALIZATION OF THE RETINOBLASTOMA PROTEIN AND THE EPSTEIN-BARR VIRUS-ENCODED NUCLEAR ANTIGEN EBNA-5
JIANG WQ; SZEKELY L; WENDELHANSEN V; RINGERTZ N; KLEIN G; ROSEN A
Journal article: GENES CHROMOSOMES AND CANCER. 1991;3(5):403-406
INVOLVEMENT OF 3P DELETIONS IN SPORADIC AND HEREDITARY FORMS OF RENAL-CELL CARCINOMA
BOLDOG F; ARHEDEN K; IMREH S; STROMBECK B; SZEKELY L; ERLANDSSON R; MARCSEK Z; SUMEGI J; MITELMAN F; KLEIN G
Journal article: MOLECULAR CANCER RESEARCH. 1991;2(6):297-303
REINTRODUCTION OF A NORMAL RETINOBLASTOMA GENE INTO RETINOBLASTOMA AND OSTEOSARCOMA CELLS INHIBITS THE REPLICATION ASSOCIATED FUNCTION OF SV40 LARGE T-ANTIGEN
UZVOLGYI E; CLASSON M; HENRIKSSON M; HUANG HJS; SZEKELY L; LEE WH; KLEIN G; SUMEGI J
Journal article: MOLECULAR CANCER RESEARCH. 1991;2(6):287-295
SUBCELLULAR-LOCALIZATION OF THE RETINOBLASTOMA PROTEIN
SZEKELY L; UZVOLGYI E; JIANG WQ; DURKO M; WIMAN KG; KLEIN G; SUMEGI J
Journal article: EXPERIMENTAL CELL RESEARCH. 1991;193(2):420-424
INOSITOL DERIVATIVES DOWN-REGULATE C-MYC INDUCING GROWTH ARREST WITHOUT DIFFERENTIATION
SZABO G; SZEKELY L; SCHABLIK M; KLEIN G; SUMEGI J; SZABO G
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Alla övriga publikationer

Letter: BLOOD CANCER JOURNAL. 2022;12(10):145
High efficacy of Azacitidine plus HAG in acute myeloid leukemia: an open-label, single-arm, multi-center, phase 2 study
Li J; Han Q; Huang Y; Wei Y; Zi J; Zhao L; Cai Z; Lu X; Xiao R; Zhang Y; Yang X; Xu H; Sun N; Zhuang W; Wu Z; Xia Y; Xu Y; He B; Zhu W; Min F; Chen Y; Ding B; Shi P; Xie J; Tang H; Liu Z; Li B; Sun Y; Qiu H; Duan L; Dovat E; Song C; SzeKely L; Dovat S; Ge Z
Corrigendum: MALARIA JOURNAL. 2021;20(1):323
Direct contact between Plasmodium falciparum and human B-cells in a novel co-culture increases parasite growth and affects B-cell growth (vol 20, 303, 2021)
Reddy SB; Nagy N; Ronnberg C; Chiodi F; Lugaajju A; Heuts F; Szekely L; Wahlgren M; Persson KEM
Preprint: BIORXIV. 2021
Basal-to-classical phenotypic switch of pancreatic cancer cells upon integration into the duodenal epithelium
Bozóky B; Moro CF; Strell C; Ernberg I; Szekely L; Gerling M; Bozóky B
Preprint: BIORXIV. 2020
Pulmonary stromal expansion and intra-alveolar coagulation are primary causes of Covid-19 death
Szekely L; Bozoky B; Bendek M; Ostad M; Lavignasse P; Haag L; Wu J; Jing X; Gupta S; Saccon E; Sönnerborg A; Cao Y; Björnstedt M; Szakos A
Preprint: BIORXIV. 2020
Tropism of SARS-CoV-2 in commonly used laboratory cell lines and their proteomic landscape during infection
Saccon E; Chen X; Mikaeloff F; Rodriguez JE; Szekely L; Vinhas BS; Krishnan S; Byrareddy SN; Frisan T; Végvári Á; Mirazimi A; Neogi U; Gupta S
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):308
Perforin deficiency within CD8⁺ T cells in sentinel lymph nodes of urothelial bladder cancer
Hartana CA; Rosenblatt R; Zirakzadeh AA; Bergman EA; Krantz D; Winerdal ME; Szekely L; Glise H; Sherif A; Winqvist O
Conference publication: HAEMATOLOGICA. 2014;99:326
IN VITRO COMPARATIVE STUDY ON DIRECT KILLING OF CLL CELLS BY SMALL TARGETED THERAPEUTIC MOLECULES
Sylvan SE; Skribek H; Norin S; Otvos R; Muhari O; Szekely L; Osterborg A
Conference publication: FREE RADICAL RESEARCH. 2009;43:63
Drug-specific responses to cytotoxic agents mediated by high levels of thioredoxin reductase 1 in human A549 cancer cells
Eriksson S; Prast-Nielsen S; Flaberg E; Szekely L; Arner E
Meeting abstract: BLOOD REVIEWS. 2007;21:S98-S99
Cytotoxic drug sensitivity of Epstein-Barr virus transformed lymphoblastoid B-cells
Markasz L; Stuber G; Flaberg E; Jernberg AG; Eksborg S; Olah E; Skribek H; Szekely L
Published conference paper: IMMUNOLOGY LETTERS. 2002;82(1-2):141-147
The X-linked lymphoproliferative disease gene product SAP is expressed in activated T and NK cells
Nagy N; Mattsson K; Maeda A; Liu AQ; Székely L; Klein E
Book chapter: ONCOGENES AND TUMOUR SUPPRESSORS. 1997;p. 3-32
Mechanisms of oncogene perturbation
Imreh S; Szekely L; Wiman KG; Klein G
Published conference paper: EXPERIMENTAL CELL RESEARCH. 1996;229(2):289-300
Intranuclear redistribution of SV40T, p53, and PML in a conditionally SV40T-immortalized cell line
Jiang WQ; Szekely L; Klein G; Ringertz N
Other: ONCOGENE. 1995;10(9):1869-1874
RESTING B-CELLS, EBV-INFECTED B-BLASTS AND ESTABLISHED LYMPHOBLASTOID CELL-LINES DIFFER IN THEIR RB, P53 AND EBNA-5 EXPRESSION PATTERNS
SZEKELY L; POKROVSKAJA K; JIANG WQ; SELIVANOVA G; LOWBEER M; RINGERTZ N; WIMAN KG; KLEIN G
Conference publication: JOURNAL OF CELLULAR BIOCHEMISTRY. 1995;:325
P53 BINDS SINGLE-STRANDED-DNA ENDS THROUGH C-TERMINAL DOMAIN AND INTERNAL DNA SEGMENTS VIA THE MIDDLE DOMAIN
SELIVANOVA G; BAKALKIN G; YAKOVLEVA T; KISELEVA E; SZEKELY L; TERENIUS L; WIMAN KG
Conference publication: BLOOD. 1995;86(10):645
Physical interaction between the retinoblastoma (RB) and promyelocytic leukemia (PML) gene products
Alcalay M; Tomassoni L; Fagioli M; Grignani F; Helin K; Szekely L; Pelicci PG
Conference publication: JOURNAL OF CELLULAR BIOCHEMISTRY. 1995;:77
P53 BINDS SINGLE-STRANDED-DNA ENDS THROUGH C-TERMINAL DOMAIN AND INTERNAL DNA SEGMENTS VIA THE MIDDLE DOMAIN
SELIVANOVA G; BAKALKIN G; YAKOVLEVA T; KISELEVA E; SZEKELY L; TERENIUS L; WIMAN KG
Conference publication: JOURNAL OF CELLULAR BIOCHEMISTRY. 1994;:181
CONTRASTING PATTERNS OF RETINOBLASTOMA PROTEIN EXPRESSION IN MOUSE EMBRYONIC STEM-CELLS AND EMBRYONIC FIBROBLASTS
SAVATIER P; SZEKELY L; WIMAN KG; SAMARUT J
Conference publication: JOURNAL OF CELLULAR BIOCHEMISTRY. 1994;:181
P53 BINDS SINGLE-STRANDED-DNA ENDS AND CATALYZES DNA RENATURATION AND STRAND TRANSFER
SELIVANOVA G; BAKALKIN G; YAKOVLEVA T; MAGNUSSON KP; SZEKELY L; KISELEVA E; KLEIN G; TERENIUS L; WIMAN KG

Forskningsbidrag

Therapeutically targetable pathophysiological changes in the bodies of Covid-19 victims and post-Covid patients identified by BSL3 autopsies
Swedish Research Council
1 December 2021 - 30 November 2025
Therapeutically targetable pathophysiological changes in the lungs and hearts of Covid-19 victims and post-Covid patients identified by BSL3 autopsies
Swedish Heart-Lung Foundation
1 January 2021 - 31 December 2021
Identification of mechanisms that control the growth of tumor cells in tissue and the development of methods that enable large-scale search of drugs targeting such control functions
Swedish Cancer Society
1 January 2015
Clinical biomarkers for ROS-based anticancer therapy
Swedish Foundation for Strategic Research
1 January 2015 - 31 December 2019
Identification of mechanisms that control the growth of tumor cells in tissue and the development of methods that enable large-scale search of drugs targeting such control functions
Swedish Cancer Society
1 January 2014
Do normal fibroblasts from patients with high and low cancer propensity differ in their ability to inhibit the growth of cancer cells?
Swedish Research Council
1 January 2013 - 31 December 2015
Determination of the drug sensitivity pattern of primary human tumor cells using automated microscopy to aid assay guided individualized therapy of cancer patients
Swedish Research Council
1 January 2011 - 31 December 2013
Do normal fibroblasts from patients with high and low cancer propensity differ in their ability to inhibit the growth of cancer cells?
Swedish Research Council
1 January 2010 - 31 December 2012

Anställningar

Anknuten till Undervisning/Handledning, Laboratoriemedicin, Karolinska Institutet, 2023-2025
Professor, Institutionen för mikrobiologi, tumör- och cellbiologi, Karolinska Institutet, 2010-2014
Universitetslektor, Institutionen för mikrobiologi, tumör- och cellbiologi, Karolinska Institutet, 2010-2010
Rådsforskare, Institutionen för mikrobiologi, tumör- och cellbiologi, Karolinska Institutet, 2007-2009
Forskare, Institutionen för mikrobiologi, tumör- och cellbiologi, Karolinska Institutet, 1996-2007
Doktorand, Institutionen för mikrobiologi, tumör- och cellbiologi, Karolinska Institutet, 1995-1995

Examina och utbildning

Docent, Inriktning: tumörbiologi, Karolinska Institutet, 2000
Läkarexamen, medicine, Production of monoclonal antibodies against vimentin (in Hungarian), Medicinsk Biologi, DOTE, 1988

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Examina och utbildning

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