Karl Ekwall

Om mig
Publikationer
Forskningsbidrag
CV
Populärvetenskap och samverkan

Om mig

Professor i medicinsk genetik, särskilt epigenetik.

Forskningsbeskrivning

Läs mer på min engelska profilsida.

Artiklar

Journal article: EPIGENOMES. 2024;8(4):39
Epigenome Mapping in Quiescent Cells Reveals a Key Role for H3K4me3 in Regulation of RNA Polymerase II Activity.
Zeng S; Ekwall K
Article: BIOMOLECULES. 2023;13(11):1662
LEO1 Is Required for Efficient Entry into Quiescence, Control of H3K9 Methylation and Gene Expression in Human Fibroblasts
Laurent M; Cordeddu L; Zahedi Y; Ekwall K
Article: CHROMOSOME RESEARCH. 2023;31(2):14
An essential role for the Ino80 chromatin remodeling complex in regulation of gene expression during cellular quiescence
Zahedi Y; Zeng S; Ekwall K
Article: NATURE COMMUNICATIONS. 2021;12(1):4800
Histone H4 lysine 20 mono-methylation directly facilitates chromatin openness and promotes transcription of housekeeping genes
Shoaib M; Chen Q; Shi X; Nair N; Prasanna C; Yang R; Walter D; Frederiksen KS; Einarsson H; Svensson JP; Liu CF; Ekwall K; Lerdrup M; Nordenskiold L; Sorensen CS
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(4):1793
The Role of Non-Catalytic Domains of Hrp3 in Nucleosome Remodeling
Dong W; Prasad P; Lennartsson A; Ekwall K
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2020;21(23):E9022-9022
High-Throughput Flow Cytometry Combined with Genetic Analysis Brings New Insights into the Understanding of Chromatin Regulation of Cellular Quiescence
Zahedi Y; Durand-Dubief M; Ekwall K
Article: BLOOD. 2020;136(3):339-352
AML displays increased CTCF occupancy associated with aberrant gene expression and transcription factor binding
Mujahed H; Miliara S; Neddermeyer A; Bengtzen S; Nilsson C; Deneberg S; Cordeddu L; Ekwall K; Lennartsson A; Lehmann S
Article: CLINICAL EPIGENETICS. 2020;12(1):74
Restoration of KMT2C/MLL3 in human colorectal cancer cells reinforces genome-wide H3K4me1 profiles and influences cell growth and gene expression
Larsson C; Cordeddu L; Siggens L; Pandzic T; Kundu S; He L; Ali MA; Pristovsek N; Hartman K; Ekwall K; Sjoblom T
Article: SCIENTIFIC REPORTS. 2020;10(1):6055
Abo1 is required for the H3K9me2 to H3K9me3 transition in heterochromatin
Dong W; Oya E; Zahedi Y; Prasad P; Svensson JP; Lennartsson A; Ekwall K; Durand-Dubief M
Article: ELIFE. 2020;9:e50556
The CDK Pef1 and protein phosphatase 4 oppose each other for regulating cohesin binding to fission yeast chromosomes
Birot A; Tormos-Perez M; Vaur S; Feytout A; Jaegy J; Gil DA; Vazquez S; Ekwall K; Javerzat J-P
Article: HUMAN GENOMICS. 2019;13(1):54
Copy number of 8q24.3 drives HSF1 expression and patient outcome in cancer: an individual patient data meta-analysis
Brusselaers N; Ekwall K; Durand-Dubief M
Article: EMBO REPORTS. 2019;20(10):e48111
H3K14 ubiquitylation promotes H3K9 methylation for heterochromatin assembly
Oya E; Nakagawa R; Yoshimura Y; Tanaka M; Nishibuchi G; Machida S; Shirai A; Ekwall K; Kurumizaka H; Tagami H; Nakayama J-I
Article: LIFE SCIENCE ALLIANCE. 2019;2(5):e201900433
Chromatin remodeler Fft3 plays a dual role at blocked DNA replication forks
Ait-Saada A; Khorosjutina O; Chen J; Kramarz K; Maksimov V; Svensson JP; Lambert S; Ekwall K
Article: GENETICS. 2019;213(1):161-172
Histone H2B Ubiquitylation Regulates Histone Gene Expression by Suppressing Antisense Transcription in Fission Yeast
Page V; Chen JJ; Durand-Dubief M; Grabowski D; Oya E; Sanso M; Martin RD; Hebert TE; Fisher RP; Ekwall K; Tanny JC
Article: EPIGENETICS AND CHROMATIN. 2019;12(1):45
Leo1 is essential for the dynamic regulation of heterochromatin and gene expression during cellular quiescence
Oya E; Durand-Dubief M; Cohen A; Maksimov V; Schurra C; Nakayama J-I; Weisman R; Arcangioli B; Ekwall K
Article: NUCLEIC ACIDS RESEARCH (NAR). 2019;47(4):1671-1691
Comprehensive profiling of the fission yeast transcription start site activity during stress and media response
Thodberg M; Thieffry A; Bornholdt J; Boyd M; Holmberg C; Azad A; Workman CT; Chen Y; Ekwall K; Nielsen O; Sandelin A
Article: NUCLEIC ACIDS RESEARCH (NAR). 2018;46(22):e135
Topokaryotyping demonstrates single cell variability and stress dependent variations in nuclear envelope associated domains
Jurisic A; Robin C; Tarlykov P; Siggens L; Schoell B; Jauch A; Ekwall K; Sorensen CS; Lipinski M; Shoaib M; Ogryzko V
Article: CURRENT BIOLOGY. 2018;28(3):383-391.e3
Repression of Cell Differentiation by a cis-Acting lincRNA in Fission Yeast
Fauquenoy S; Migeot V; Finet O; Yague-Sanz C; Khorosjutina O; Ekwall K; Hermand D
Article: PLOS ONE. 2018;13(8):e0201101
The binding of Chp2's chromodomain to methylated H3K9 is essential for Chp2's role in heterochromatin assembly in fission yeast
Maksimov V; Oya E; Tanaka M; Kawaguchi T; Hachisuka A; Ekwall K; Bjerling P; Nakayama J-I
Article: SCIENTIFIC DATA. 2017;4:170112
Data Descriptor: FANTOM5 CAGE profiles of human and mouse samples
Noguchi S; Arakawa T; Fukuda S; Furuno M; Hasegawa A; Hori F; Ishikawa-Kato S; Kaida K; Kaiho A; Kanamori-Katayama M; Kawashima T; Kojima M; Kubosaki A; Manabe R-I; Murata M; Nagao-Sato S; Nakazato K; Ninomiya N; Nishiyori-Sueki H; Noma S; Saijyo E; Saka A; Sakai M; Simon C; Suzuki N; Tagami M; Watanabe S; Yoshida S; Arner P; Axton RA; Babina M; Baillie JK; Barnett TC; Beckhouse AG; Blumenthal A; Bodega B; Bonetti A; Briggs J; Brombacher F; Carlisle AJ; Clevers HC; Davis CA; Detmar M; Dohi T; Edge ASB; Edinger M; Ehrlund A; Ekwall K; Endoh M; Enomoto H; Eslami A; Fagiolini M; Fairbairn L; Farach-Carson MC; Faulkner GJ; Ferrai C; Fisher ME; Forrester LM; Fujita R; Furusawa J-I; Geijtenbeek TB; Gingeras T; Goldowitz D; Guhl S; Guler R; Gustincich S; Ha TJ; Hamaguchi M; Hara M; Hasegawa Y; Herlyn M; Heutink P; Hitchens KJ; Hume DA; Ikawa T; Ishizu Y; Kai C; Kawamoto H; Kawamura YI; Kempfle JS; Kenna TJ; Kere J; Khachigian LM; Kitamura T; Klein S; Klinken SP; Knox AJ; Kojima S; Koseki H; Koyasu S; Lee W; Lennartsson A; Mackay-sim A; Mejhert N; Mizuno Y; Morikawa H; Morimoto M; Moro K; Morris KJ; Motohashi H; Mummery CL; Nakachi Y; Nakahara F; Nakamura T; Nakamura Y; Nozaki T; Ogishima S; Ohkura N; Ohno H; Ohshima M; Okada-Hatakeyama M; Okazaki Y; Orlando V; Ovchinnikov DA; Passier R; Patrikakis M; Pombo A; Pradhan-Bhatt S; Qin X-Y; Rehli M; Rizzu P; Roy S; Sajantila A; Sakaguchi S; Sato H; Satoh H; Savvi S; Saxena A; Schmidl C; Schneider C; Schulze-Tanzil GG; Schwegmann A; Sheng G; Shin JW; Sugiyama D; Sugiyama T; Summers KM; Takahashi N; Takai J; Tanaka H; Tatsukawa H; Tomoiu A; Toyoda H; van de Wetering M; van den Berg LM; Verardo R; Vijayan D; Wells CA; Winteringham LN; Wolvetang E; Yamaguchi Y; Yamamoto M; Yanagi-Mizuochi C; Yoneda M; Yonekura Y; Zhang PG; Zucchelli S; Abugessaisa I; Arner E; Harshbarger J; Kondo A; Lassmann T; Lizio M; Sahin S; Sengstag T; Severin J; Shimoji H; Suzuki M; Suzuki H; Kawai J; Kondo N; Itoh M; Daub CO; Kasukawa T; Kawaji H; Carninci P; Forrest ARR; Hayashizaki Y
Article: COLD SPRING HARBOR PROTOCOLS. 2017;2017(8):pdb.top079772
Genetic Analysis of Schizosaccharomyces pombe.
Ekwall K; Thon G
Article: COLD SPRING HARBOR PROTOCOLS. 2017;2017(8):pdb.prot091736
Ethyl Methanesulfonate Mutagenesis in Schizosaccharomyces pombe.
Ekwall K; Thon G
Article: COLD SPRING HARBOR PROTOCOLS. 2017;2017(8):pdb.prot091728
Mating-Type Determination in Schizosaccharomyces pombe.
Ekwall K; Thon G
Article: COLD SPRING HARBOR PROTOCOLS. 2017;2017(7):pdb.prot091710
Spore Analysis and Tetrad Dissection of Schizosaccharomyces pombe.
Ekwall K; Thon G
Article: COLD SPRING HARBOR PROTOCOLS. 2017;2017(7):pdb.prot091702
Selecting Schizosaccharomyces pombe Diploids.
Ekwall K; Thon G
Article: COLD SPRING HARBOR PROTOCOLS. 2017;2017(7):pdb.prot091694
Setting up Schizosaccharomyces pombe Crosses/Matings.
Ekwall K; Thon G
Article: NUCLEIC ACIDS RESEARCH (NAR). 2017;45(9):5153-5169
CTG repeat-targeting oligonucleotides for down-regulating Huntingtin expression
Zaghloul EM; Gissberg O; Moreno PMD; Siggens L; Hallbrink M; Jorgensen AS; Ekwall K; Zain R; Wengel J; Lundin KE; Smith CIE
Article: EMBO JOURNAL. 2017;36(10):1364-1378
A second Wpl1 anti-cohesion pathway requires dephosphorylation of fission yeast kleisin Rad21 by PP4
Birot A; Eguienta K; Vazquez S; Claverol S; Bonneu M; Ekwall K; Javerzat J-P; Vaur S
Article: ONCOTARGET. 2017;8(17):28812-28825
Comprehensive mapping of the effects of azacitidine on DNA methylation, repressive/permissive histone marks and gene expression in primary cells from patients with MDS and MDS-related disease
Tobiasson M; Abdulkadir H; Lennartsson A; Katayama S; Marabita F; De Paepe A; Karimi M; Krjutskov K; Einarsdottir E; Grovdal M; Jansson M; Ben Azenkoud A; Corddedu L; Lehmann S; Ekwall K; Kere J; Hellstrom-Lindberg E; Ungerstedt J
Article: BLOOD. 2017;129(7):e13-e25
Cancer-specific changes in DNA methylation reveal aberrant silencing and activation of enhancers in leukemia
Qu Y; Siggens L; Cordeddu L; Gaidzik VI; Karlsson K; Bullinger L; Doehner K; Ekwall K; Lehmann S; Lennartsson A
Article: EMBO REPORTS. 2016;17(5):753-768
Regulating retrotransposon activity through the use of alternative transcription start sites
Persson J; Steglich B; Smialowska A; Boyd M; Bornholdt J; Andersson R; Schurra C; Arcangioli B; Sandelin A; Nielsen O; Ekwall K
Article: ONCOTARGET. 2016;7(16):22103-22115
Mutations in histone modulators are associated with prolonged survival during azacitidine therapy
Tobiasson M; McLornan DP; Karimi M; Dimitriou M; Jansson M; Ben Azenkoud A; Jadersten M; Lindberg G; Abdulkadir H; Kulasekararaj A; Ungerstedt J; Lennartsson A; Ekwall K; Mufti GJ; Hellstrom-Lindberg E
Article: EMBO REPORTS. 2015;16(12):1673-1687
The Paf1 complex factors Leo1 and Paf1 promote local histone turnover to modulate chromatin states in fission yeast
Sadeghi L; Prasad P; Ekwall K; Cohen A; Svensson JP
Article: PLOS BIOLOGY. 2015;13(12):e1002315
The Constrained Maximal Expression Level Owing to Haploidy Shapes Gene Content on the Mammalian X Chromosome
Hurst LD; Ghanbarian AT; Forrest ARR; Huminiecki L
Article: COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY. 2015;7(7):a018770
Epigenetic Regulation of Chromatin States in Schizosaccharomyces pombe
Allshire RC; Ekwall K
Article: GENOME RESEARCH. 2015;25(6):872-883
A nucleosome turnover map reveals that the stability of histone H4 Lys20 methylation depends on histone recycling in transcribed chromatin
Svensson JP; Shukla M; Menendez-Benito V; Norman-Axelsson U; Audergon P; Sinha I; Tanny JC; Allshire RC; Ekwall K
Article: PLOS GENETICS. 2015;11(3):e1005101
The Fun30 Chromatin Remodeler Fft3 Controls Nuclear Organization and Chromatin Structure of Insulators and Subtelomeres in Fission Yeast
Steglich B; Stralfors A; Khorosjutina O; Persson J; Smialowska A; Javerzat J-P; Ekwall K
Article: MOLECULAR AND CELLULAR BIOLOGY. 2015;35(4):662-674
Panspecies Small-Molecule Disruptors of Heterochromatin-Mediated Transcriptional Gene Silencing
Castonguay E; White SA; Kagansky A; St-Cyr DJ; Castillo AG; Brugger C; White R; Bonilla C; Spitzer M; Earnshaw WC; Schalch T; Ekwall K; Tyers M; Allshire RC
Article: NATURE COMMUNICATIONS. 2015;6:6066
The statistical geometry of transcriptome divergence in cell-type evolution and cancer
Liang C; Forrest ARR; Wagner GP
Article: PLOS ONE. 2015;10(2):e0116702
ABCE1 Is a Highly Conserved RNA Silencing Suppressor
Kaerblane K; Gerassimenko J; Nigul L; Piirsoo A; Smialowska A; Vinkel K; Kylsten P; Ekwall K; Swoboda P; Truve E; Sarmiento C
Article: PLOS ONE. 2015;10(3):e0117581
Discovery of Molecular Markers to Discriminate Corneal Endothelial Cells in the Human Body
Yoshihara M; Ohmiya H; Hara S; Kawasaki S; Hayashizaki Y; Itoh M; Kawaji H; Tsujikawa M; Nishida K
Article: EPIGENETICS AND CHROMATIN. 2015;8(1):4
Transcription-coupled recruitment of human CHD1 and CHD2 influences chromatin accessibility and histone H3 and H3.3 occupancy at active chromatin regions
Siggens L; Cordeddu L; Rnnerblad M; Lennartsson A; Ekwall K
Article: BLOOD. 2014;123(17):e79-e89
Analysis of the DNA methylome and transcriptome in granulopoiesis reveals timed changes and dynamic enhancer methylation
Ronnerblad M; Andersson R; Olofsson T; Douagi I; Karimi M; Lehmann S; Hoof I; de Hoon M; Itoh M; Nagao-Sato S; Kawaji H; Lassmann T; Carninci P; Hayashizaki Y; Forrest ARR; Sandelin A; Ekwall K; Arner E; Lennartsson A
Article: BLOOD. 2014;123(17):e46-e57
High-throughput transcription profiling identifies putative epigenetic regulators of hematopoiesis
Prasad P; Ronnerblad M; Arner E; Itoh M; Kawaji H; Lassmann T; Daub CO; Forrest ARR; Lennartsson A; Ekwall K
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2014;111(14):5289-5294
Differential roles of epigenetic changes and Foxp3 expression in regulatory T cell-specific transcriptional regulation
Morikawa H; Ohkura N; Vandenbon A; Itoh M; Nagao-Sato S; Kawaji H; Lassmann T; Carninci P; Hayashizaki Y; Forrest ARR; Standley DM; Date H; Sakaguchi S
Article: NATURE. 2014;507(7493):462-470
A promoter-level mammalian expression atlas
Forrest ARR; Kawaji H; Rehli M; Baillie JK; de Hoon MJL; Haberle V; Lassmann T; Kulakovskiy IV; Lizio M; Itoh M; Andersson R; Mungall CJ; Meehan TF; Schmeier S; Bertin N; Jorgensen M; Dimont E; Arner E; Schmidl C; Schaefer U; Medvedeva YA; Plessy C; Vitezic M; Severin J; Semple CA; Ishizu Y; Young RS; Francescatto M; Alam I; Albanese D; Altschuler GM; Arakawa T; Archer JAC; Arner P; Babina M; Rennie S; Balwierz PJ; Beckhouse AG; Pradhan-Bhatt S; Blake JA; Blumenthal A; Bodega B; Bonetti A; Briggs J; Brombacher F; Burroughs AM; Califano A; Cannistraci CV; Carbajo D; Chen Y; Chierici M; Ciani Y; Clevers HC; Dalla E; Davis CA; Detmar M; Diehl AD; Dohi T; Drablos F; Edge ASB; Edinger M; Ekwall K; Endoh M; Enomoto H; Fagiolini M; Fairbairn L; Fang H; Farach-Carson MC; Faulkner GJ; Favorov AV; Fisher ME; Frith MC; Fujita R; Fukuda S; Furlanello C; Furuno M; Furusawa J-I; Geijtenbeek TB; Gibson AP; Gingeras T; Goldowitz D; Gough J; Guhl S; Guler R; Gustincich S; Ha TJ; Hamaguchi M; Hara M; Harbers M; Harshbarger J; Hasegawa A; Hasegawa Y; Hashimoto T; Herlyn M; Hitchens KJ; Sui SJH; Hofmann OM; Hoof I; Hori F; Huminiecki L; Iida K; Ikawa T; Jankovic BR; Jia H; Joshi A; Jurman G; Kaczkowski B; Kai C; Kaida K; Kaiho A; Kajiyama K; Kanamori-Katayama M; Kasianov A; Kasukawa T; Katayama S; Kato S; Kawaguchi S; Kawamoto H; Kawamura YI; Kawashima T; Kempfle JS; Kenna TJ; Kere J; Khachigian LM; Kitamura T; Klinken SP; Knox AJ; Kojima M; Kojima S; Kondo N; Koseki H; Koyasu S; Krampitz S; Kubosaki A; Kwon AT; Laros JFJ; Lee W; Lennartsson A; Li K; Lilje B; Lipovich L; Mackay-sim A; Manabe R-I; Mar JC; Marchand B; Mathelier A; Mejhert N; Meynert A; Mizuno Y; Morais DADL; Morikawa H; Morimoto M; Moro K; Motakis E; Motohashi H; Mummery CL; Murata M; Nagao-Sato S; Nakachi Y; Nakahara F; Nakamura T; Nakamura Y; Nakazato K; Van Nimwegen E; Ninomiya N; Nishiyori H; Noma S; Nozaki T; Ogishima S; Ohkura N; Ohmiya H; Ohno H; Ohshima M; Okada-Hatakeyama M; Okazaki Y; Orlando V; Ovchinnikov DA; Pain A; Passier R; Patrikakis M; Persson H; Piazza S; Prendergast JGD; Rackham OJL; Ramilowski JA; Rashid M; Ravasi T; Rizzu P; Roncador M; Roy S; Rye MB; Saijyo E; Sajantila A; Saka A; Sakaguchi S; Sakai M; Sato H; Satoh H; Savvi S; Saxena A; Schneider C; Schultes EA; Schulze-Tanzil GG; Schwegmann A; Sengstag T; Sheng G; Shimoji H; Shimoni Y; Shin JW; Simon C; Sugiyama D; Sugiyama T; Suzuki M; Suzuki N; Swoboda RK; 't Hoen PAC; Tagami M; Takahashi N; Takai J; Tanaka H; Tatsukawa H; Tatum Z; Thompson M; Toyoda H; Toyoda T; Valen E; van de Wetering M; van den Berg LM; Verardo R; Vijayan D; Vorontsov IE; Wasserman WW; Watanabe S; Wells CA; Winteringham LN; Wolvetang E; Wood EJ; Yamaguchi Y; Yamamoto M; Yoneda M; Yonekura Y; Yoshida S; Zabierowski SE; Zhang PG; Zhao X; Zucchelli S; Summers KM; Suzuki H; Daub CO; Kawai J; Heutink P; Hide W; Freeman TC; Lenhard B; Bajic VB; Taylor MS; Makeev VJ; Sandelin A; Hume DA; Carninci P; Hayashizaki Y
Article: NATURE. 2014;507(7493):455-461
An atlas of active enhancers across human cell types and tissues
Andersson R; Gebhard C; Miguel-Escalada I; Hoof I; Bornholdt J; Boyd M; Chen Y; Zhao X; Schmidl C; Suzuki T; Ntini E; Arner E; Valen E; Li K; Schwarzfischer L; Glatz D; Raithel J; Lilje B; Rapin N; Bagger FO; Jorgensen M; Andersen PR; Bertin N; Rackham O; Burroughs AM; Baillie JK; Ishizu Y; Shimizu Y; Furuhata E; Maeda S; Negishi Y; Mungall CJ; Meehan TF; Lassmann T; Itoh M; Kawaji H; Kondo N; Kawai J; Lennartsson A; Daub CO; Heutink P; Hume DA; Jensen TH; Suzuki H; Hayashizaki Y; Mueller F; Forrest ARR; Carninci P; Rehli M; Sandelin A
Article: NATURE STRUCTURAL & MOLECULAR BIOLOGY. 2014;21(3):236-243
Centromeric histone H2B monoubiquitination promotes noncoding transcription and chromatin integrity
Sadeghi L; Siggens L; Svensson JP; Ekwall K
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2014;444(2):254-259
RNAi mediates post-transcriptional repression of gene expression in fission yeast Schizosaccharomyces pombe
Smialowska A; Djupedal I; Wang J; Kylsten P; Swoboda P; Ekwall K
Article: BIOCHEMICAL SOCIETY TRANSACTIONS. 2013;41(6):1640-1647
A snapshot of Snf2 enzymes in fission yeast
Prasad P; Ekwall K
Journal article: PLOS ONE. 2013;8(10):10.1371/annotation/c6430c
Correction: Telomeric Repeats Facilitate CENP-ACnp1 Incorporation via Telomere Binding Proteins
Article: PLOS ONE. 2013;8(7):e69673
Telomeric Repeats Facilitate CENP-A^Cnp1 Incorporation via Telomere Binding Proteins
Castillo AG; Pidoux AL; Catania S; Durand-Dubief M; Choi ES; Hamilton G; Ekwall K; Allshire RC
Article: PLOS GENETICS. 2013;9(3):e1003371
DNA Topoisomerase III Localizes to Centromeres and Affects Centromeric CENP-A Levels in Fission Yeast
Norman-Axelsson U; Durand-Dubief M; Prasad P; Ekwall K
Article: EMBO JOURNAL. 2012;31(23):4388-4403
CHD1 remodelers regulate nucleosome spacing in vitro and align nucleosomal arrays over gene coding regions in S. pombe
Pointner J; Persson J; Prasad P; Norman-Axelsson U; Stralfors A; Khorosjutina O; Krietenstein N; Svensson JP; Ekwall K; Korber P
Article: MOLECULAR AND CELLULAR BIOLOGY. 2012;32(19):4035-4043
Mediator Promotes CENP-A Incorporation at Fission Yeast Centromeres
Carlsten JO; Szilagyi Z; Liu B; Lopez MD; Szaszi E; Djupedal I; Nystrom T; Ekwall K; Gustafsson CM; Zhu X
Article: PLOS GENETICS. 2012;8(9):e1002985
Factors That Promote H3 Chromatin Integrity during Transcription Prevent Promiscuous Deposition of CENP-A^Cnp1 in Fission Yeast
Choi ES; Stralfors A; Catania S; Castillo AG; Svensson JP; Pidoux AL; Ekwall K; Allshire RC
Article: NUCLEUS. 2012;3(1):77-87
The inner nuclear membrane proteins Man1 and Ima1 link to two different types of chromatin at the nuclear periphery in S. pombe
Steglich B; Filion GJ; van Steensel B; Ekwall K
Article: BLOOD. 2011;118(20):5573-5582
Prognostic DNA methylation patterns in cytogenetically normal acute myeloid leukemia are predefined by stem cell chromatin marks
Deneberg S; Guardiola P; Lennartsson A; Qu Y; Gaidzik V; Blanchet O; Karimi M; Bengtzen S; Nahi H; Uggla B; Tidefelt U; Hoglund M; Paul C; Ekwall K; Doehner K; Lehmann S
Article: PLOS COMPUTATIONAL BIOLOGY. 2011;7(8):e1002163
Podbat: A Novel Genomic Tool Reveals Swr1-Independent H2A.Z Incorporation at Gene Coding Sequences through Epigenetic Meta-Analysis
Sadeghi L; Bonilla C; Stralfors A; Ekwall K; Svensson JP
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2011;286(26):23600-23607
Identification of Noncoding Transcripts from within CENP-A Chromatin at Fission Yeast Centromeres
Choi ES; Stralfors A; Castillo AG; Durand-Dubief M; Ekwall K; Allshire RC
Article: SCIENCE. 2011;332(6032):930-936
Comparative Functional Genomics of the Fission Yeasts
Rhind N; Chen Z; Yassour M; Thompson DA; Haas BJ; Habib N; Wapinski I; Roy S; Lin MF; Heiman DI; Young SK; Furuya K; Guo Y; Pidoux A; Chen HM; Robbertse B; Goldberg JM; Aoki K; Bayne EH; Berlin AM; Desjardins CA; Dobbs E; Dukaj L; Fan L; FitzGerald MG; French C; Gujja S; Hansen K; Keifenheim D; Levin JZ; Mosher RA; Mueller CA; Pfiffner J; Priest M; Russ C; Smialowska A; Swoboda P; Sykes SM; Vaughn M; Vengrova S; Yoder R; Zeng Q; Allshire R; Baulcombe D; Birren BW; Brown W; Ekwall K; Kellis M; Leatherwood J; Levin H; Margalit H; Martienssen R; Nieduszynski CA; Spatafora JW; Friedman N; Dalgaard JZ; Baumann P; Niki H; Regev A; Nusbaum C
Article: TRANSCRIPTION. 2011;2(2):66-70
Topoisomerases, chromatin and transcription termination.
Durand-Dubief M; Svensson JP; Persson J; Ekwall K
Article: PLOS GENETICS. 2011;7(3):e1001334
The FUN30 Chromatin Remodeler, Fft3, Protects Centromeric and Subtelomeric Domains from Euchromatin Formation
Stralfors A; Walfridsson J; Bhuiyan H; Ekwall K
Article: JOURNAL OF MOLECULAR BIOLOGY. 2011;405(3):653-665
The Role of MutY Homolog (Myh1) in Controlling the Histone Deacetylase Hst4 in the Fission Yeast Schizosaccharomyces pombe
Chang D-Y; Shi G; Durand-Dubief M; Ekwall K; Lu A-L
Journal article: BLOOD. 2010;116(21):231
Global and HOX Gene DNA Methylation In Normal Karyotype Acute Myeloid Leukemia: Clinical Implications and Molecular Correlations
Deneberg S; Lennartsson A; Uggla B; Gaidzik V; Corbacioglu A; Nahi H; Dohner K; Ekwall K; Tidefelt U; Hoglund M; Lehmann S
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2010;285(39):29729-29737
A Chromatin-remodeling Protein Is a Component of Fission Yeast Mediator
Khorosjutina O; Wanrooij PH; Walfridsson J; Szilagyi Z; Zhu X; Baraznenok V; Ekwall K; Gustafsson CM
Article: EMBO JOURNAL. 2010;29(13):2126-2134
Topoisomerase I regulates open chromatin and controls gene expression in vivo
Durand-Dubief M; Persson J; Norman U; Hartsuiker E; Ekwall K
Article: EPIGENOMICS. 2010;2(3):377-393
Genome-wide mapping of histone modifications and mass spectrometry reveal H4 acetylation bias and H3K36 methylation at gene promoters in fission yeast
Sinha I; Buchanan L; Roennerblad M; Bonilla C; Durand-Dubief M; Shevchenko A; Grunstein M; Stewart AF; Ekwall K
Article: NATURE STRUCTURAL & MOLECULAR BIOLOGY. 2010;17(2):251-257
Schizosaccharomyces pombe genome-wide nucleosome mapping reveals positioning mechanisms distinct from those of Saccharomyces cerevisiae
Lantermann AB; Straub T; Stralfors A; Yuan G-C; Ekwall K; Korber P
Article: MOLECULAR AND CELLULAR BIOLOGY. 2010;30(3):657-674
Fission Yeast Iec1-Ino80-Mediated Nucleosome Eviction Regulates Nucleotide and Phosphate Metabolism
Hogan CJ; Aligianni S; Durand-Dubief M; Persson J; Will WR; Webster J; Wheeler L; Mathews CK; Elderkin S; Oxley D; Ekwall K; Varga-Weisz PD
Article: EMBO JOURNAL. 2009;28(24):3832-3844
Analysis of small RNA in fission yeast; centromeric siRNAs are potentially generated through a structured RNA
Djupedal I; Kos-Braun IC; Mosher RA; Soderholm N; Simmer F; Hardcastle TJ; Fender A; Heidrich N; Kagansky A; Bayne E; Wagner EGH; Baulcombe DC; Allshire RC; Ekwall K
Article: PLOS GENETICS. 2009;5(11):e1000726
The Schizosaccharomyces pombe JmjC-Protein, Msc1, Prevents H2A.Z Localization in Centromeric and Subtelomeric Chromatin Domains
Buchanan L; Durand-Dubief M; Roguev A; Sakalar C; Wilhelm B; Stralfors A; Shevchenko A; Aasland R; Shevchenko A; Ekwall K; Stewart AF
Article: EMBO REPORTS. 2009;10(9):1009-1014
HAT-HDAC interplay modulates global histone H3K14 acetylation in gene-coding regions during stress
Johnsson A; Durand-Dubief M; Xue-Franzen Y; Ronnerblad M; Ekwall K; Wright A
Article: METHODS. 2009;48(3):218-225
Genome-wide mapping of nucleosome positions in Schizosaccharomyces pombe
Lantermann A; Stralfors A; Fagerstrom-Billai F; Korber P; Ekwall K
Article: METHODS IN MOLECULAR BIOLOGY. 2009;529:279-295
Chromatin immunoprecipitation using microarrays.
Durand-Dubief M; Ekwall K
Article: SCIENCE. 2008;322(5901):602-606
Splicing factors facilitate RNAi-directed silencing in fission yeast
Bayne EH; Portoso M; Kagansky A; Kos-Braun IC; Urano T; Ekwall K; Alves F; Rappsilber J; Allshire RC
Article: BIOESSAYS. 2008;30(6):526-529
Heterochromatin tells CENP-A where to go
Durand-Dubief M; Ekwall K
Article: EMBO JOURNAL. 2008;27(1):111-121
Cell-cycle regulation of cohesin stability along fission yeast chromosomes
Bernard P; Schmidt CK; Vaur S; Dheur S; Drogat J; Genier S; Ekwall K; Uhlmann F; Javerzat J-P
Article: MOLECULAR CELL. 2007;28(6):1029-1044
A NASP (N1/N2)-related protein, Sim3, binds CENP-A and is required for its deposition at fission yeast Centromeres
Dunleavy EM; Pidoux AL; Monet M; Bonilla C; Richardson W; Hamilton GL; Ekwall K; McLaughlin PJ; Allshire RC
Article: CURRENT BIOLOGY. 2007;17(14):1219-1224
The chromatin-remodeling factor FACT contributes to centromeric heterochromatin independently of RNAi
Lejeune E; Bortfeld M; White SA; Pidoux AL; Ekwall K; Allshire RC; Ladurner AG
Article: EMBO JOURNAL. 2007;26(12):2868-2879
A genome-wide role for CHD remodelling factors and Nap1 in nucleosome disassembly
Walfridsson J; Khorosjutina O; Matikainen P; Gustafsson CM; Ekwall K
Article: EMBO JOURNAL. 2007;26(10):2477-2488
Specific functions for the fission yeast Sirtuins Hst2 and Hst4 in gene regulation and retrotransposon silencing
Durand-Dubief M; Sinha I; Fagerstroem-Billai F; Bonilla C; Wright A; Grunstein M; Ekwall K
Article: PLOS ONE. 2007;2(4):e386
Genome-Wide Studies of Histone Demethylation Catalysed by the Fission Yeast Homologues of Mammalian LSD1
Opel M; Lando D; Bonilla C; Trewick SC; Boukaba A; Walfridsson J; Cauwood J; Werler PJH; Carr AM; Kouzarides T; Murzina NV; Allshire RC; Ekwall K; Laue ED
Article: GENETICS. 2007;175(4):1549-1560
Interaction of Epe1 with the heterochromatin assembly pathway in Schizosaccharomyces pombe
Isaac S; Walfridsson J; Zohar T; Lazar D; Kahan T; Ekwall K; Cohen A
Article: MOLECULAR AND CELLULAR BIOLOGY. 2007;27(3):1069-1082
Individual Subunits of the Ssn6-Tup11/12 corepressor are selectively required for repression of different target genes
Fagerstrom-Billai F; Durand-Dubief M; Ekwall K; Wright APH
Article: MOLECULAR CELL. 2006;22(2):169-178
Genome-wide occupancy profile of mediator and the Srb8-11 module reveals interactions with coding regions
Zhu XF; Wirén M; Sinha I; Rasmussen NN; Linder T; Holmberg S; Ekwall K; Gustafsson CM
Article: CHROMOSOME RESEARCH. 2006;14(1):95-105
Genome-wide patterns of histone modifications in fission yeast
Sinha I; Wirén M; Ekwall K
Article: GENES & DEVELOPMENT. 2005;19(19):2301-2306
RNA Pol II subunit Rpb7 promotes centromeric transcription and RNAi-directed chromatin silencing
Djupedal I; Portoso M; Spåhr H; Bonilla C; Gustafsson CM; Allshire RC; Ekwall K
Article: EMBO JOURNAL. 2005;24(16):2906-2918
Genome wide analysis of nucleosome density histone acetylation and HDAC function in fission yeast
Wirén M; Silverstein RA; Sinha I; Walfridsson J; Lee HM; Laurenson P; Pillus L; Robyr D; Grunstein M; Ekwall K
Journal article: NATURE. 2005;435(7046):1275-1279
RNA-interference-directed chromatin modification coupled to RNA polymerase II transcription (Retracted article. See vol. 437, pg. 1057, 2005)
Schramke V; Sheedy DM; Denli AM; Bonila C; Ekwall K; Hannon GJ; Allshire RC
Article: NUCLEIC ACIDS RESEARCH (NAR). 2005;33(9):2868-2879
The CHD remodeling factor Hrp1 stimulates CENP-A loading to centromeres
Walfridsson J; Bjerling P; Thalen M; Yoo EJ; Park SD; Ekwall K
Article: NUCLEIC ACIDS RESEARCH (NAR). 2004;32(15):4421-4428
A novel type of silencing factor, Clr2, is necessary for transcriptional silencing at various chromosomal locations in the fission yeast Schizosaccharomyces pombe
Bjerling P; Ekwall K; Egel R; Thon G
Article: MOLECULAR BIOLOGY OF THE CELL. 2004;15(3):1425-1435
Ago1 and Dcr1, two core components of the RNA interference pathway, functionally diverge from Rdp1 in regulating cell cycle events in Schizosaccharomyces pombe
Carmichael JB; Provost P; Ekwall K; Hobman TC
Article: YEAST. 2004;21(1):25-39
A DNA microarray for fission yeast: minimal changes in global gene expression after temperature shift
Xue YT; Haas SA; Brino L; Gusnanto A; Reimers M; Talibi D; Vingron M; Ekwall K; Wright APH
Article: CHROMOSOME RESEARCH. 2004;12(6):535-542
The roles of histone modifications and small RNA in centromere function
Ekwall K
Article: JOURNAL OF CELL SCIENCE. 2003;116(19):4035-4042
Distinct centromere domain structures with separate functions demonstrated in live fission yeast cells
Appelgren H; Kniola B; Ekwall K
Article: CURRENT GENETICS. 2003;43(4):273-280
An inventory of the P-type ATPases in the fission yeast Schizosaccharomyces pombe
Okorokova-Façanha AL; Okorokov LA; Ekwall K
Article: EMBO JOURNAL. 2003;22(11):2776-2787
Alp13, an MRG family protein, is a component of fission yeast Clr6 histone deacetylase required for genomic integrity
Nakayama J; Xiao GP; Noma K; Malikzay A; Bjerling P; Ekwall K; Kobayashi R; Grewal SIS
Article: CELL CYCLE. 2003;2(2):73-75
Similar Mechanisms Drive Centromeric Silencing and Gene Repression
Silverstein RA; Ekwall K
Article: CURRENT BIOLOGY. 2003;13(1):68-72
A new role for the transcriptional corepressor SIN3; Regulation of centromeres
Silverstein RA; Richardson W; Levin H; Allshire R; Ekwall K
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2002;99(26):16648-16653
Dicer is required for chromosome segregation and gene silencing in fission yeast cells
Provost P; Silverstein RA; Dishart D; Walfridsson J; Djupedal I; Kniola B; Wright A; Samuelsson B; Rådmark O; Ekwall K
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2002;295(4):970-974
Hrp3, a chromodomain helicase/ATPase DNA binding protein, is required for heterochromatin silencing in fission yeast
Yoo EJ; Jang YK; Lee MA; Bjerling P; Kim JB; Ekwall K; Seong RH; Park SD
Article: JOURNAL OF CELL BIOLOGY. 2002;157(6):1029-1039
The endoplasmic reticulum cation P-type ATPase Cta4p is required for control of cell shape and microtubule dynamics
Façanha ALO; Appelgren H; Tabish M; Okorokov L; Ekwall K
Article: MOLECULAR AND CELLULAR BIOLOGY. 2002;22(7):2170-2181
Functional divergence between histone deacetylases in fission yeast by distinct cellular localization and in vivo specificity
Bjerling P; Silverstein RA; Thon G; Caudy A; Grewal S; Ekwall K
Article: MOLECULAR BIOLOGY OF THE CELL. 2001;12(9):2767-2775
The domain structure of centromeres is conserved from fission yeast to humans
Kniola B; O'Toole E; McIntosh JR; Mellone B; Allshire R; Mengarelli S; Hultenby K; Ekwall K
Article: NUCLEIC ACIDS RESEARCH (NAR). 2000;28(9):2004-2011
Fission yeast Hrp1, a chromodomain ATPase, is required for proper chromosome segregation and its overexpression interferes with chromatin condensation
Yoo EJ; Jin YH; Jang YK; Bjerling P; Tabish M; Hong SH; Ekwall K; Park SD
Article: GENETICS. 1999;153(3):1153-1169
Fission yeast mutants that alleviate transcriptional silencing in centromeric flanking repeats and disrupt chromosome segregation
Ekwall K; Cranston G; Allshire RC
Article: CURRENT GENETICS. 1999;35(2):82-87
Transient inhibition of histone deacetylase activity overcomes silencing in the mating-type region in fission yeast
Olsson TGS; Silverstein RA; Ekwall K; Sunnerhagen P
Article: MOLECULAR AND CELLULAR BIOLOGY. 1999;19(3):2351-2365
A new member of the Sin3 family of corepressors is essential for cell viability and required for retroelement propagation in fission yeast
Dang VD; Benedik MJ; Ekwall K; Choi J; Allshire RC; Levin HL
Article: NUCLEIC ACIDS RESEARCH (NAR). 1998;26(13):3247-3254
Genetic characterisation of hda1⁺, a putative fission yeast histone deacetylase gene
Olsson TGS; Ekwall K; Allshire RC; Sunnerhagen P; Partridge JF; Richardson WA
Article: CELL. 1997;91(7):1021-1032
Transient inhibition of histone deacetylation alters the structural and functional imprint at fission yeast centromeres
Ekwall K; Olsson T; Turner BM; Cranston G; Allshire RC
Article: JOURNAL OF CELL SCIENCE. 1996;109:2637-2648
Mutations in the fission yeast silencing factors clr4(+) and rik1(+) disrupt the localisation of the chromo domain protein Swi6p and impair centromere function
Ekwall K; Nimmo ER; Javerzat JP; Borgstrom B; Egel R; Cranston G; Allshire R
Article: SCIENCE. 1995;269(5229):1429-1431
THE CHROMODOMAIN PROTEIN SWI6 - A KEY COMPONENT AT FISSION YEAST CENTROMERES
EKWALL K; JAVERZAT JP; LORENTZ A; SCHMIDT H; CRANSTON G; ALLSHIRE R
Article: GENES & DEVELOPMENT. 1995;9(2):218-233
MUTATIONS DEREPRESSING SILENT CENTROMERIC DOMAINS IN FISSION YEAST DISRUPT CHROMOSOME SEGREGATION
ALLSHIRE RC; NIMMO ER; EKWALL K; JAVERZAT JP; CRANSTON G
Journal article: CURRENT GENETICS. 1994;26(5-6):553-556
PHYSICAL MAPPING OF THE SCHIZOSACCHAROMYCES-POMBE HISTONE GENES
LIND M; LUNDERIUS C; EKWALL K; OLSSON T
Journal article: GENETICS. 1994;136(1):53-64
MUTATIONS IN RIK1, CLR2, CLR3 AND CLR4 GENES ASYMMETRICALLY DEREPRESS THE SILENT MATING-TYPE LOCI IN FISSION YEAST
EKWALL K; RUUSALA T
Journal article: NUCLEIC ACIDS RESEARCH (NAR). 1993;21(4):855-861
THE SILENT P MATING TYPE LOCUS IN FISSION YEAST CONTAINS 2 AUTONOMOUSLY REPLICATING SEQUENCES
OLSSON T; EKWALL K; RUUSALA T
Journal article: MOLECULAR GENETICS AND GENOMICS. 1992;233(1-2):136-144
THE NAM8 GENE IN SACCHAROMYCES-CEREVISIAE ENCODES A PROTEIN WITH PUTATIVE RNA-BINDING MOTIFS AND ACTS AS A SUPPRESSOR OF MITOCHONDRIAL SPLICING DEFICIENCIES WHEN OVEREXPRESSED
EKWALL K; KERMORGANT M; DUJARDIN G; GROUDINSKY O; SLONIMSKI PP
Journal article: CURRENT GENETICS. 1992;21(4-5):331-338
TRANS-ACTING FACTORS AND PROPERLY POSITIONED DNA ELEMENTS REPRESS MATING-TYPE GENES IN FISSION YEAST
EKWALL K; OLSSON T; RUUSALA T
Journal article: YEAST. 1991;7(7):745-755
REPRESSION OF A MATING TYPE CASSETTE IN THE FISSION YEAST BY 4 DNA ELEMENTS
EKWALL K; NIELSEN O; RUUSALA T
Journal article: NUCLEIC ACIDS RESEARCH (NAR). 1991;19(5):1150
BUDDING YEAST CAN1 GENE AS A SELECTION MARKER IN FISSION YEAST
EKWALL K; RUUSALA T
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Alla övriga publikationer

Preprint: BIORXIV. 2024
TORC1-dependent control of fission yeast cohesin
Besson D; Vaur S; Vazquez S; Tournier S; Gachet Y; Birot A; Claverol S; Marston A; Damdimopoulos A; Ekwall K; Javerzat J-P
Letter: LEUKEMIA. 2024;38(3):663-666
The exon-junction complex helicase eIF4A3 holds therapeutic potential in acute myeloid leukemia
Miliara S; Cozzi E; Zhong X; Chan I; Ekwall K; Lehmann S; Lennartsson A; Bartek J; Kanellis DC
Corrigendum: MOLECULAR AND CELLULAR BIOLOGY. 2021;41(7):e0017921-e00121
Mediator Promotes CENP-A Incorporation at Fission Yeast Centromeres (vol 32, pg 4035, 2012)
Carlsten JO; Szilagyi Z; Liu B; Lopez MD; Szaszi E; Djupedal I; Nystrom T; Ekwall K; Gustafsson CM; Zhu X
Preprint: BIORXIV. 2019
The CDK Pef1 and Protein Phosphatase 4 oppose each other for regulating cohesin binding to fission yeast chromosomes
Birot A; Tormos-Pérez M; Vaur S; Feytout A; Jaegy J; Gil DA; Vazquez S; Ekwall K; Javerzat J-P
Preprint: BIORXIV. 2018
Topokaryotyping demonstrates single cell variability and stress dependent variations in nuclear envelope associated domains
Jurisic A; Robin C; Tarlykov P; Siggens L; Schoell B; Jauch A; Ekwal K; Sørensen CS; Lipinski M; Shoaib M; Ogryzko V
Preprint: BIORXIV. 2018
Comprehensive profiling of the fission yeast transcription start site activity during stress and media response
Thodberg M; Thieffry A; Bornholdt J; Boyd M; Holmberg C; Azad A; Workman C; Chen Y; Ekwall K; Nielsen O; Sandelin A
Conference publication: HAEMATOLOGICA. 2016;101:70
MODEST EPIGENETIC EFFECT OF AZACITIDINE IN GENOME-WIDE MAPPING OF DNA METHYLATION, H3K9ME3, H3K18AC AND GENE EXPRESSION IN MDS PROGENITORS
Tobiasson M; Ali HA; Lennartsson A; Katayama S; Marabita F; Karimi M; Khrjutskhov K; Einarsdottir E; Jansson M; Ben Azenkoud A; Ekwall K; Kere J; Hellstrom-Lindberg E; Ungerstedt J
Conference publication: HAEMATOLOGICA. 2016;101:209-210
DIFFERENTIAL DNA METHYLATION IN CYTOGENETICALLY NORMAL ACUTE MYELOID LEUKEMIA IS LINKED TO ALTERED GENE EXPRESSION OF ENHANCER TARGET GENES
Qu Y; Siggens L; Cordeddu L; Ekwall K; Lehmann S; Lennartsson A
Conference publication: BLOOD. 2015;126(23):2839
Mutations in Histone Modulators Are Associated with Prolonged Survival during Azacitidine Therapy
Tobiasson M; MeLornan D; Karimi M; Dimitriou M; Jansson M; Ben Azenkoud A; Jadersten M; Lindberg G; Abdulkadir H; Kulasekararaj AG; Ungerstedt J; Lennartsson A; Ekwall K; Mufti GJ; Hellstrom-Lindberg E
Meeting abstract: LEUKEMIA RESEARCH. 2015;39:S69
IN VITRO AZACITIDINE CULTURE INDUCES DNA DEMETHYLATION AND INCREASED MRNA-LEVELS IN PRIMARY MDS PROGENITOR CELLS
Abdulkadir H; Tobiasson M; Lennartsson A; Katayama S; Marabita F; Karimi M; Qu Y; Einarsdottir E; Govdal M; Jansson M; Ben Azenkoud A; Lehmann S; Ekwall K; Kere J; Hellstom-Lindberg E; Ungerstedt J
Review: BIOMED RESEARCH INTERNATIONAL. 2015;2015:347571-17
The Roles of SNF2/SWI2 Nucleosome Remodeling Enzymes in Blood Cell Differentiation and Leukemia
Prasad P; Lennartsson A; Ekwall K
Conference publication: BLOOD. 2014;124(21):4613
Mutations in Histone Modulators and HOXA5 Methylation Levels Affects Survival in Azacitidine Treated MDS Patients
Tobiasson M; Karimi M; Dimitriou M; Qu Y; Lennartsson A; Ali HA; Unnikrishnan A; Jadersten M; Jansson M; Ben Azenkoud A; Pimanda JE; Ekwall K; Ungerstedt J; Lehmann S; Hellstrom-Lindberg E
Review: JOURNAL OF INTERNAL MEDICINE. 2014;276(3):201-214
Epigenetics, chromatin and genome organization: recent advances from the ENCODE project
Siggens L; Ekwall K
Letter: LEUKEMIA. 2014;28(2):411-413
Azacitidine induces profound genome-wide hypomethylation in primary myelodysplastic bone marrow cultures but may also reduce histone acetylation
Grovdal M; Karimi M; Tobiasson M; Reinius L; Jansson M; Ekwall K; Ungerstedt J; Kere J; Greco D; Hellstrom-Lindberg E
Editorial comment: EPIGENOMICS. 2014;6(5):451-454
Epigenetic activation and inactivation of centromeres
Svensson JP; Ekwall K
Review: NUCLEUS. 2013;4(5):379-389
Transcriptional regulation at the yeast nuclear envelope
Steglich B; Sazer S; Ekwall K
Corrigendum: MOLECULAR AND CELLULAR BIOLOGY. 2012;32(24):5151
Mediator Promotes CENP-A Incorporation at Fission Yeast Centromeres (vol 32, pg 4035, 2012)
Carlsten JO; Szilagyi Z; Liu B; Lopez MD; Szaszi E; Djupedal I; Nystrom T; Ekwall K; Gustafsson CM; Zhu X
Meeting abstract: BLOOD. 2012;120(21):2334
Analysis of DNA Methylation and Transcription During Granulopoiesis Reveals Timed Methylation Changes in Low CpG Areas That Correlate with Changed Transcriptional Activity
Michelle R; Tor O; Douagi I; Lehmann S; Ekwall K; Arner E; Lennartsson A
Book chapter: ENCYCLOPEDIA OF MOLECULAR CELL BIOLOGY AND MOLECULAR MEDICINE. 2011;p.
Heterochromatin and Euchromatin—Organization, Boundaries, and Gene Regulation
Strålfors A; Ekwall K
Editorial comment: EMBO JOURNAL. 2011;30(10):1875-1876
New insights into how chromatin remodellers direct CENP-A to centromeres
Prasad P; Ekwall K
Review: EXPERIMENTAL CELL RESEARCH. 2010;316(8):1316-1323
Chd1 remodelers maintain open chromatin and regulate the epigenetics of differentiation
Persson J; Ekwall K
Conference publication: BLOOD. 2010;116(21):107
Global and HOX Gene DNA Methylation In Normal Karyotype Acute Myeloid Leukemia: Clinical Implications and Molecular Correlations
Deneberg S; Lennartsson A; Uggla B; Gaidzik V; Corbacioglu A; Nahi H; Dohner K; Ekwall K; Tidefelt U; Hoglund M; Lehmann S
Review: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2009;1790(9):863-868
Histone modification patterns and epigenetic codes
Lennartsson A; Ekwall K
Review: CELL RESEARCH. 2009;19(3):282-295
Epigenetics: heterochromatin meets RNAi
Djupedal I; Ekwall K
Editorial comment: SCIENCE. 2008;320(5876):624-625
Molecular biology - The paradox of silent heterochromatin
Djupedal I; Ekwall K
Review: ANNUAL REVIEW OF GENETICS. 2007;41:63-81
Epigenetic control of centromere behavior
Ekwall K
Editorial comment: NATURE STRUCTURAL & MOLECULAR BIOLOGY. 2007;14(3):178-179
'Arc' escorts siRNAs in heterochromatin assembly
Ekwall K
Review: TRENDS IN GENETICS. 2005;21(11):608-615
Genome-wide analysis of HDAC function
Ekwall K
Corrigendum: NATURE. 2005;437(7061):1057
RNA-interference-directed chromatin modification coupled to RNA polymerase II transcription (Retraction of vol 435, pg 1275, 2005)
Schramke V; Sheedy DM; Denli AM; Bonila C; Ekwall K; Hannon GJ; Allshire RC
Review: CURRENT GENETICS. 2005;47(1):1-17
Sin3: a flexible regulator of global gene expression and genome stability
Silverstein RA; Ekwall K
Editorial comment: MOLECULAR CELL. 2004;13(3):304-305
The RITS complex - A direct link between small RNA and heterochromatin
Ekwall K
Corrigendum: JOURNAL OF CELL SCIENCE. 2004;117(1):129
Distinct centromere domain structures with separate functions demonstrated in live fission yeast cells. (vol 116, pg 4035, 2003)
Appelgren H; Kniola B; Ekwall K
Conference publication: YEAST. 2003;20:S118
Dicer is required for chromosome segregation and gene silencing in fission yeast cells.
Djupedal I; Provost P; Silverstein R; Dishart D; Walfridsson J; Kniola B; Rådmark BSO; Ekwall K
Conference publication: YEAST. 2003;20:S333
A DNA microarray for genome-wide gene expression analysis in fission yeast.
Xue YT; Haas S; Brino L; Gusnanto A; Riemers M; Talibi D; Vingron M; Ekwall K; Wright APH
Conference publication: YEAST. 2003;20:S235
A role of P-type Cta4 ATPase and calcineurin in calcium homeostasis and endoplasmic reticulum stress in fission yeast.
Lustoza AC; Ekwall K; Okorokov L; Okorokova-Facanha A
Corrigendum: MOLECULAR AND CELLULAR BIOLOGY. 2002;22(14):5257-5258
Functional divergence between histone deacetylases in fission yeast by distinct cellular localization and in vivo specificity (vol 22, pg 2170, 2002)
Bjerling P; Silverstein RA; Thon G; Caudy A; Grewal S; Ekwall K
Published conference paper: BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH. 2002;35(5):499-507
Centromere domain organization and histone modifications
Bjerling P; Ekwall K
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Forskningsbidrag

Epigenetics, chromatin remodeling in cellular quiescence and cancer
Swedish Research Council
1 January 2022 - 31 December 2024
Epigenetics, chromatin remodeling and cancer
Swedish Research Council
1 January 2019 - 31 December 2021
Epigenetics, chromatin transformation and cancer
Swedish Cancer Society
1 January 2018
SWI2/SNF2 Enzymes in Epigenome Remodeling Cell Differentiation and as Putative Targets for Epigenetic Therapy
Swedish Research Council
1 January 2017 - 31 December 2018
Chromatin transformation enzymes, cell differentiation and new strategies for epigenetic cancer treatment
Swedish Cancer Society
1 January 2017
Chromatin transformation enzymes, cell differentiation and new strategies for epigenetic cancer treatment
Swedish Cancer Society
1 January 2016
Epigenetic mechanisms in centromere and gene regulation
Swedish Research Council
1 January 2015 - 31 December 2018
Chromatin transformation enzymes, cell differentiation and new strategies for epigenetic cancer treatment
Swedish Cancer Society
1 January 2015
Characterization of SNF2 enzymes, their role in human blood cell differentiation and as putative targets for epigenetic therapy
Swedish Research Council
1 January 2014 - 31 December 2016
'SNF2' chromatin transformation enzymes and cell differentiation
Swedish Cancer Society
1 January 2014
Epigenetic mechanisms in centromere and gene regulation
Swedish Research Council
1 January 2011 - 31 December 2014
Clinical epigenetics of acute leukemia
Knut and Alice Wallenberg Foundation
1 January 2011 - 1 January 2016

Anställningar

Professor, Medicin, Huddinge, Karolinska Institutet, 2024-

Examina och utbildning

Professor-competent in Molecular Biology, Södertörn University, 2007
Docent, Molekylär genetik, Karolinska Institutet, 1999
Doctor of Philosophy (Molecular Biology), Uppsala University, 1994
Bachelor of Microbiology, Microbiology, Uppsala University, 1988

Priser och utmärkelser

The Göran Gustafsson Prize in Molecular Biology, Göran Gustafsson Foundation, 2009
Royal Swedish Academy of Sciences (KVA) Research Fellow, Royal Swedish Academy of Sciences, 2007
Högskolelektor, Södertörn University, 2000
Appointed as Assistant Professor (Swedish Medical Research Council position ‘MFR’), Karolinska Institute, 1997

Om mig

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Forskningsbidrag

Anställningar

Examina och utbildning

Priser och utmärkelser

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