Karine Chemin

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: RMD OPEN. 2024;10(4):e004510
Arthritis progressors have a decreased frequency of circulating autoreactive T cells during the at-risk phase of rheumatoid arthritis.
Turcinov S; Sharma RK; De Vries C; Cîrciumaru A; Gerstner C; Mathsson-Alm L; Raposo B; Dubnovitsky A; Rönnblom L; Kwok WW; Chemin K; Malmström V; Hensvold A
Article: RHEUMATOLOGY. 2024;63(5):1466-1473
Autoantibodies against the melanoma differentiation-associated protein 5 in patients with dermatomyositis target the helicase domains
Van Gompel E; Demirdal D; Fernandes-Cerqueira C; Horuluoglu B; Galindo-Feria A; Wigren E; Graslund S; De Langhe E; Benveniste O; Notarnicola A; Chemin K; Lundberg IE
Article: EMBO MOLECULAR MEDICINE. 2023;15(10):e17240
Single-cell profiling of muscle-infiltrating T cells in idiopathic inflammatory myopathies
Argyriou A; Horuluoglu B; Galindo-Feria AS; Diaz-Boada JS; Sijbranda M; Notarnicola A; Dani L; van Vollenhoven A; Ramskold D; Nennesmo I; Dastmalchi M; Lundberg IE; Diaz-Gallo L-M; Chemin K
Article: CLINICAL RHEUMATOLOGY. 2023;42(10):2889-2895
Occurrence and localization of FOXP3+cells in kidney biopsies in lupus nephritis and ANCA-associated vasculitis
Zickert A; Jankovic MR; Malmstrom V; Chemin K; Gunnarsson I
Article: ARTHRITIS & RHEUMATOLOGY. 2023;75(5):673-684
Diversity and Clonality of T Cell Receptor Repertoire and Antigen Specificities in Small Joints of Early Rheumatoid Arthritis
Turcinov S; af Klint E; Van Schoubroeck B; Kouwenhoven A; Mia S; Chemin K; Wils H; Van Hove C; De Bondt A; Keustermans K; Van Houdt J; Reumers J; Felix N; Rao NL; Peeters P; Stevenaert F; Klareskog L; McKinnon M; Baker D; Suri A; Malmstroem V
Article: KIDNEY INTERNATIONAL. 2023;103(5):973-985
Identification of proteinase 3 autoreactive CD4+T cells and their T-cell receptor repertoires in antineutrophil cytoplasmic antibody-associated vasculitis
Sharma RK; Yoosuf N; Afonso M; Scheffschick A; Avik A; Bartoletti A; Horuluoglu B; Boada JSD; Boddul SK; Jonasdottir AD; Lovstrom B; Brauner H; Raposo B; Chemin K; Bruchfeld A; Gunnarsson I; Malmstrom V
Article: SCIENTIFIC REPORTS. 2022;12(1):11876
Integrated single cell and spatial transcriptomics reveal autoreactive differentiated B cells in joints of early rheumatoid arthritis
Hardt U; Carlberg K; af Klint E; Sahlstrom P; Larsson L; van Vollenhoven A; Machado SH; Israelsson L; Amara K; Chemin K; Korotkova M; Hedestam GBK; Catrina AI; Teichmann SA; Stahl PL; Malmstrom V
Article: NATURE COMMUNICATIONS. 2022;13(1):4046
Single cell sequencing identifies clonally expanded synovial CD4⁺ T_PH cells expressing GPR56 in rheumatoid arthritis
Argyriou A; Wadsworth MH; Lendvai A; Christensen SM; Hensvold AH; Gerstner C; van Vollenhoven A; Kravarik K; Winkler A; Malmstrom V; Chemin K
Article: JOURNAL OF AUTOIMMUNITY. 2022;131:102857
Modulating T-cell activation with antisense oligonucleotides targeting lymphocyte cytosolic protein 2
Iyer VS; Boddul SV; Johnsson A-K; Raposo B; Sharma RK; Shen Y; Kasza Z; Lim KW; Chemin K; Nilsson G; Malmstrom V; Phan AT; Wermeling F
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:826152
Rituximab in Systemic Lupus Erythematosus: Transient Effects on Autoimmunity Associated Lymphocyte Phenotypes and Implications for Immunogenicity
Faustini F; Sippl N; Stalesen R; Chemin K; Dunn N; Fogdell-Hahn A; Gunnarsson I; Malmstroem V
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2021;205(1):44-52
Arthritis in systemic lupus erythematosus is characterized by local IL-17A and IL-6 expression in synovial fluid
Sippl N; Faustini F; Ronnelid J; Turcinov S; Chemin K; Gunnarsson I; Malmstrom V
Article: ANNALS OF THE RHEUMATIC DISEASES. 2021;80(2):194-202
Natural killer cells and type II interferon in Ro/SSA and La/SSB autoantibody-exposed newborns at risk of congenital heart block
Ivanchenko M; Thorlacius GE; Hedlund M; Ottosson V; Meneghel L; Bjorkander S; Ossoinak A; Tingstrom J; Bremme K; Sverremark-Ekstrom E; Gemzell-Danielsson K; Sonesson S-E; Chemin K; Wahren-Herlenius M
Article: BMC IMMUNOLOGY. 2020;21(1):27
Multi-HLA class II tetramer analyses of citrulline-reactive T cells and early treatment response in rheumatoid arthritis
Gerstner C; Turcinov S; Hensvold AH; Chemin K; Uchtenhagen H; Ramwadhdoebe TH; Dubnovitsky A; Kozhukh G; Ronnblom L; Kwok WW; Achour A; Catrina A; van Baarsen LGM; Malmstrom V
Article: FRONTIERS IN IMMUNOLOGY. 2019;9:3033
Differential ACPA Binding to Nuclear Antigens Reveals a PAD-Independent Pathway and a Distinct Subset of Acetylation Cross-Reactive Autoantibodies in Rheumatoid Arthritis
Lloyd KA; Wigerblad G; Sahlstrom P; Garimella MG; Chemin K; Steen J; Titcombe PJ; Marklein B; Zhou D; Stalesen R; Ossipova E; Lundqvist C; Ekwall O; Ronnelid J; Mueller DL; Karlsson MCI; Kaplan MJ; Skriner K; Klareskog L; Wermeling F; Malmstrom V; Gronwall C
Article: ANNALS OF THE RHEUMATIC DISEASES. 2018;77(10):1454-1462
Systematic approach demonstrates enrichment of multiple interactions between non-HLA risk variants and HLA-DRB1 risk alleles in rheumatoid arthritis
Diaz-Gallo L-M; Ramskold D; Shchetynsky K; Folkersen L; Chemin K; Brynedal B; Uebe S; Okada Y; Alfredsson L; Klareskog L; Padyukov L
Article: ARTHRITIS RESEARCH & THERAPY. 2018;20(1):188
T-cell transcriptomics from peripheral blood highlights differences between polymyositis and dermatomyositis patients
Houtman M; Ekholm L; Hesselberg E; Chemin K; Malmstrom V; Reed AM; Lundberg IE; Padyukov L
Article: JOURNAL OF AUTOIMMUNITY. 2018;90:28-38
T cells are influenced by a long non-coding RNA in the autoimmune associated PTPN2 locus
Houtman M; Shchetynsky K; Chemin K; Hensvold AH; Ramskold D; Tandre K; Eloranta M-L; Ronnblom L; Uebe S; Catrina AI; Malmstrom V; Padyukov L
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2018;192(3):259-270
Diminished CXCR5 expression in peripheral blood of patients with Sjogren's syndrome may relate to both genotype and salivary gland homing
Aqrawi LA; Ivanchenko M; Bjork A; Sepulveda JIR; Imgenberg-Kreuz J; Kvarnstrom M; Haselmayer P; Jensen JL; Nordmark G; Chemin K; Skarstein K; Wahren-Herlenius M
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2018;48(4):655-669
EOMES-positive CD4⁺ Tcells are increased in PTPN22 (1858T) risk allele carriers
Chemin K; Ramskold D; Diaz-Gallo L-M; Herrath J; Houtman M; Tandre K; Ronnblom L; Catrina A; Malmstrom V
Article: ARTHRITIS & RHEUMATOLOGY. 2016;68(5):1124-1135
A Novel HLA-DRB1*10:01-Restricted T Cell Epitope From Citrullinated Type II Collagen Relevant to Rheumatoid Arthritis
Chemin K; Pollastro S; James E; Ge C; Albrecht I; Herrath J; Gerstner C; Tandre K; Rizzi TS; Ronnblom L; Catrina A; Holmdahl R; Klareskog L; de Vries N; Malmstrom V
Article: JOURNAL OF CLINICAL INVESTIGATION. 2015;125(12):4612-4624
Development of autoantibodies against muscle-specific FHL1 in severe inflammatory myopathies
Albrecht I; Wick C; Hallgren A; Tjarnlund A; Nagaraju K; Andrade F; Thompson K; Coley W; Phadke A; Diaz-Gallo L-M; Bottai M; Nennesmo I; Chemin K; Herrath J; Johansson K; Wikberg A; Ytterberg AJ; Zubarev RA; Danielsson O; Krystufkova O; Vencovsky J; Landegren N; Wahren-Herlenius M; Padyukov L; Kampe O; Lundberg IE
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2014;44(10):2979-2989
Surface expression of CD39 identifies an enriched Treg-cell subset in the rheumatic joint, which does not suppress IL-17A secretion
Herrath J; Chemin K; Albrecht I; Catrina AI; Malmstrom V
Article: NATURE IMMUNOLOGY. 2013;14(7):723-731
VAMP7 controls T cell activation by regulating the recruitment and phosphorylation of vesicular Lat at TCR-activation sites
Larghi P; Williamson DJ; Carpier J-M; Dogniaux S; Chemin K; Bohineust A; Danglot L; Gaus K; Galli T; Hivroz C
Article: JOURNAL OF IMMUNOLOGY. 2012;189(5):2159-2168
Cytokine Secretion by CD4⁺ T Cells at the Immunological Synapse Requires Cdc42-Dependent Local Actin Remodeling but Not Microtubule Organizing Center Polarity
Chemin K; Bohineust A; Dogniaux S; Tourret M; Guegan S; Miro F; Hivroz C
Article: BLOOD. 2012;119(18):4174-4181
The Ets-1 transcription factor is required for Stat1-mediated T-bet expression and IgG2a class switching in mouse B cells
Hai VN; Mouly E; Chemin K; Luinaud R; Despres R; Fermand J-P; Arnulf B; Bories J-C
Article: CRITICAL REVIEWS IN IMMUNOLOGY. 2012;32(2):139-155
Crosstalk between T Lymphocytes and Dendritic Cells
Hivroz C; Chemin K; Tourret M; Bohineust A
Article: PLOS ONE. 2011;6(5):e19680
Force Generation upon T Cell Receptor Engagement
Husson J; Chemin K; Bohineust A; Hivroz C; Henry N
Article: JOURNAL OF IMMUNOLOGY. 2010;185(11):6809-6818
T Cell Polarity at the Immunological Synapse Is Required for CD154-Dependent IL-12 Secretion by Dendritic Cells
Tourret M; Guegan S; Chemin K; Dogniaux S; Miro F; Bohineust A; Hivroz C
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2010;207(10):2113-2125
The Ets-1 transcription factor controls the development and function of natural regulatory T cells
Mouly E; Chemin K; Nguyen HV; Chopin M; Mesnard L; Leite-de-Moraes M; Burlen-defranoux O; Bandeira A; Bories J-C
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2009;39(7):1966-1976
Hypomorphic mutation of ZAP70 in human results in a late onset immunodeficiency and no autoimmunity
Picard C; Dogniaux S; Chemin K; Maciorowski Z; Lim A; Mazerolles F; Rieux-Laucat F; Stolzenberg M-C; Debre M; Magny J-P; Le Deist F; Fischer A; Hivroz C
Article: BLOOD. 2008;111(7):3579-3590
Cognate CD4⁺ T-cell-dendritic cell interactions induce migration of immature dendritic cells through dissolution of their podosomes
Nobile C; Lind M; Miro F; Chemin K; Tourret M; Occhipinti G; Dogniaux S; Amigorena S; Hivroz C
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2007;136(4):609-614
Detection and follow-up of fibroblast growth factor receptor 3 expression on bone marrow and circulating plasma cells by flow cytometry in patients with t(4;14) multiple myeloma
Chandesris MO; Soulier J; Labaume S; Crinquette A; Repellini L; Chemin K; Malphettes M; Fieschi C; Asli B; Uzunhan Y; Fermand JP; Bories JC; Arnulf B
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2004;101(44):15712-15717
The Ets-1 transcription factor is required for complete pre-T cell receptor function and allelic exclusion at the T cell receptor β locus
Eyquem S; Chemin K; Fasseu M; Bories JC
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2004;34(11):3187-3196
The development of early and mature B cells is impaired in mice deficient for the Ets-1 transcription factor
Eyquem S; Chemin K; Fasseu M; Chopin M; Sigaux F; Cumano A; Bories JC
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Conference publication: ARTHRITIS & RHEUMATOLOGY. 2023;75:3468-3469
The Occurrence and Phenotype of Autoreactive T Cells in the At-Risk Phase of Rheumatoid Arthritis
Turcinov S; de Vries C; Sharma RK; Gerstner C; Raposo B; Dubnovitsky A; Kwok W; Chemin K; Malmstrom V; Hensvold A
Conference publication: ARTHRITIS & RHEUMATOLOGY. 2023;75:4891-4892
Monoclonal Anti-MDA5 Autoantibodies Derived from a Patient with Dermatomyositis Target the Hel2i Domain of the MDA5 Protein
Van Gompel E; Stalesen R; Gronwall C; van Vollenhoven A; Israelsson L; Lundberg I; Malmstrom V; Chemin K; Joshua V
Conference publication: ANNALS OF THE RHEUMATIC DISEASES. 2023;82:292
TISSUE RESIDENT MEMORY AND CYTOTOXIC T CELLS ARE CLONALLY EXPANDED IN THE MUSCLE OF PATIENTS WITH IDIOPATHIC INFLAMMATORY MYOPATHIES
Galindo-Feria AS; Argyriou A; Horuluoglu B; Diaz-Boada JS; Notarnicola A; Dani L; Van Vollenhoven A; Ramskold D; Nennesmo I; Dastmalchi M; Lundberg IE; Diaz-Gallo LM; Chemin K
Conference publication: ANNALS OF THE RHEUMATIC DISEASES. 2023;82:575
DETECTION OF HISRS SPECIFIC AUTOREACTIVE CD4+T CELLS IN PATIENTS WITH IDIOPATHIC INFLAMMATORY MYOPATHIES
Horuluoglu B; Galindo-Feria AS; Kumar R; Kozhukh G; Diaz-Boada JS; Ramskold D; Chemin K; Malmstrom V; Lundberg IE
Editorial comment: NATURE REVIEWS RHEUMATOLOGY. 2023;19(5):259-260
Citrulline immunity in RA: CD8⁺ T cells enter the scene
Chemin K; Malmstrom V
Conference publication: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2023;41(2):442-443
IDENTIFICATION OF JO-1 SPECIFIC AUTOREACTIVE T CELLS IN IDIOPATHIC INFLAMMATORY MYOPATHIES
Horuluoglu B; Galindo-Feria AS; Kozhukh G; Dubnovitsky A; Chemin K; Malmstrom V; Lundberg IE
Conference publication: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2023;41(2):458-459
CHARACTERIZATION OF ANTI-MDA5 AUTOANTIBODY BINDING SITES AND CORRELATION WITH CLINICAL FINDINGS IN SWEDISH DERMATOMYOSITIS PATIENTS
Van Gompel E; Demirdal D; Horuluoglu B; Galindo-Feria A; Fernandes-Cerqueira C; Dastmalchi M; Wigren E; Graslund S; Lundberg IE; Notarnicola A; Chemin K
Conference publication: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2023;41(2):428
MUSCLE T CELL SIGNATURES AND CLONALLY EXPANDED CYTOTOXIC T CELLS ARE IDENTIFIED IN IDIOPATHIC INFLAMMATORY MYOPATHIES USING SINGLE-CELL SEQUENCING
Argyriou A; Galindo-Feria A; Horuluoglu B; Diaz-Boada JS; Notarnicola A; Dani L; Van Vol-Lenhoven A; Ramskold D; Nennesmo I; Dastmalchi M; Lundberg IE; Diaz-Gallo LM; Chemin K
Conference publication: ANNALS OF THE RHEUMATIC DISEASES. 2022;81:751-752
CHARACTERISATION OF SWEDISH MYOSITIS PATIENTS WITH ANTI-MDA5 AUTOANTIBODIES AND CORRELATION OF CLINICAL FEATURES WITH AUTOANTIBODY LEVELS
Demirdal D; Van Gompel E; Wigren E; Dastmalchi M; Horuluoglu B; Galindo-Feria AS; Graslund S; Chemin K; Lundberg IE; Notarnicola A
Preprint: MEDRXIV. 2021
Integrated Single Cell and Spatial Transcriptomics Reveal Autoreactive Differentiated B Cells in Joints of Early Rheumatoid Arthritis
Hardt U; Carlberg K; Klint EA; Sahlström P; Larsson L; van Vollenhoven A; Machado SH; Israelsson L; Amara K; Chemin K; Korotkova M; Hedestam GBK; Catrina AI; Teichmann SA; Ståhl PL; Malmström V
Review: FRONTIERS IN IMMUNOLOGY. 2019;10:353
Effector Functions of CD4+T Cells at the Site of Local Autoimmune Inflammation-Lessons From Rheumatoid Arthritis
Chemin K; Gerstner C; Malmstrom V
Letter: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2019;195(3):305-309
FoxP3⁺CXCR5⁺CD4⁺ T cell frequencies are increased in peripheral blood of patients with primary Sjogren's syndrome
Ivanchenko M; Aqrawi LA; Bjork A; Wahren-Herlenius M; Chemin K
Letter: ARTHRITIS & RHEUMATOLOGY. 2016;68(8):2053-2054
Is citrullination required for the presence of restricted clonotypes reacting with type II collagen? Comment on the article by Chemin et al Reply
Chemin K; Albrecht I; Pollastro S; de Vries N; Holmdahl R; Malmstrom V
Review: CURRENT OPINION IN RHEUMATOLOGY. 2016;28(2):181-188
Is rheumatoid arthritis an autoimmune disease?
Chemin K; Klareskog L; Malmstrom V
Review: SEMINARS IN IMMUNOPATHOLOGY. 2010;32(2):107-116
ZAP70: a master regulator of adaptive immunity
Fischer A; Picard C; Chemin K; Dogniaux S; Le Deist F; Hivroz C

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