Karima Chergui

Om mig
Publikationer
CV
Populärvetenskap och samverkan

Om mig

Karima Chergui är universitetslektor och forskargruppsledare för Molekylär
neurofysiologi [1].
[1] http://ki.se/fyfa/molekylar-neurofysiologi

Artiklar

Article: MOLECULAR PSYCHIATRY. 2026;31(3):1785-1798
Altered acetylcholine modulations and corticoaccumbal pathway in P11-linked social dysfunction
Dautan D; Camargo A; Branzell N; Brioschi VI; Doyon D; Covatta E; Marongiu R; Kaplitt M; Chergui K; Zhang X; Svenningsson P
Article: NATURE COMMUNICATIONS. 2024;15(1):8176
Claustrum and dorsal endopiriform cortex complex cell-identity is determined by Nurr1 and regulates hallucinogenic-like states in mice
Mantas I; Flais I; Masarapu Y; Ionescu T; Frapard S; Jung F; Le Merre P; Saarinen M; Tiklova K; Salmani BY; Gillberg L; Zhang X; Chergui K; Carlen M; Giacomello S; Hengerer B; Perlmann T; Svenningsson P
Article: NATURE COMMUNICATIONS. 2023;14(1):5804
Prosaposin maintains lipid homeostasis in dopamine neurons and counteracts experimental parkinsonism in rodents
He Y; Kaya I; Shariatgorji R; Lundkvist J; Wahlberg LU; Nilsson A; Mamula D; Kehr J; Zareba-Paslawska J; Biverstal H; Chergui K; Zhang X; Andren PE; Svenningsson P
Article: NPJ PARKINSONS DISEASE. 2023;9(1):56
Aberrant somatic calcium channel function in cNurr1 and LRRK2-G2019S mice
Skiteva O; Yao N; Mantas I; Zhang X; Perlmann T; Svenningsson P; Chergui K
Article: BIOMOLECULES. 2022;13(1):51
Age- and Sex-Dependent Behavioral and Neurochemical Alterations in hLRRK2-G2019S BAC Mice
Yao N; Skiteva O; Chergui K
Article: BIOMOLECULES. 2022;12(11):1635
Neuronal Firing and Glutamatergic Synapses in the Substantia Nigra Pars Reticulata of LRRK2-G2019S Mice
Sitzia G; Skiteva O; Chergui K
Article: SCIENCE ADVANCES. 2022;8(34):eabo1543
PRC2-mediated repression is essential to maintain identity and function of differentiated dopaminergic and serotonergic neurons
Toskas K; Yaghmaeian-Salmani B; Skiteva O; Paslawski W; Gillberg L; Skara V; Antoniou I; Sodersten E; Svenningsson P; Chergui K; Ringner M; Perlmann T; Holmberg J
Article: JOURNAL OF NEUROCHEMISTRY. 2022;161(2):158-172
LRRK2-G2019S mice display alterations in glutamatergic synaptic transmission in midbrain dopamine neurons
Skiteva O; Yao N; Sitzia G; Chergui K
Article: TRANSLATIONAL PSYCHIATRY. 2021;11(1):530
Ketamine induces opposite changes in AMPA receptor calcium permeability in the ventral tegmental area and nucleus accumbens
Skiteva O; Yao N; Chergui K
Article: NEUROPHARMACOLOGY. 2020;174:108136
NMDA receptors are altered in the substantia nigra pars reticulata and their blockade ameliorates motor deficits in experimental parkinsonism
Sitzia G; Mantas I; Zhang X; Svenningsson P; Chergui K
Article: FRONTIERS IN AGING NEUROSCIENCE. 2020;12:84
Deficits in Motor Performance, Neurotransmitters and Synaptic Plasticity in Elderly and Experimental Parkinsonian Mice Lacking GPR37
Zhang X; Mantas I; Fridjonsdottir E; Andren PE; Chergui K; Svenningsson P
Article: MOLECULAR PSYCHIATRY. 2018;23(10):2066-2077
Ketamine and its metabolite (2R,6R)-hydroxynorketamine induce lasting alterations in glutamatergic synaptic plasticity in the mesolimbic circuit
Yao N; Skiteva O; Zhang X; Svenningsson P; Chergui K
Article: FRONTIERS IN PHARMACOLOGY. 2018;9:166
Striatal Tyrosine Hydroxylase Is Stimulated via TAAR1 by 3-Iodothyronamine, But Not by Tyramine or β-Phenylethylamine
Zhang X; Mantas I; Alvarsson A; Yoshitake T; Shariatgorji M; Pereira M; Nilsson A; Kehr J; Andren PE; Millan MJ; Chergui K; Svenningsson P
Article: NEUROSCIENCE LETTERS. 2018;666:11-16
High frequency stimulation induces LTD of AMPA receptor-mediated postsynaptic responses and LTP of synaptically-evoked firing in the dorsolateral striatum
Skiteva O; Yao N; Nouhi M; Chergui K
Article: CNS NEUROSCIENCE & THERAPEUTICS. 2018;24(2):144-153
CIQ, a positive allosteric modulator of GluN2C/D-containing N-methyl-D-aspartate receptors, rescues striatal synaptic plasticity deficit in a mouse model of Parkinson's disease
Nouhi M; Zhang X; Yao N; Chergui K
Article: LEARNING & MEMORY. 2016;23(9):479-485
The GABA_A receptor agonist muscimol induces an age- and region-dependent form of long-term depression in the mouse striatum
Zhang X; Yao N; Chergui K
Article: NEUROPHARMACOLOGY. 2015;92:108-115
Dopamine depletion of the striatum causes a cell-type specific reorganization of GluN2B-and GluN2D-containing NMDA receptors
Zhang X; Chergui K
Article: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2015;18(4):pyu052
Induction of Cannabinoid- and N-Methyl-D-Aspartate Receptor-Mediated Long-Term Depression in the Nucleus Accumbens and Dorsolateral Striatum Is Region and Age Dependent
Zhang X; Feng Z-J; Chergui K
Article: BRITISH JOURNAL OF PHARMACOLOGY. 2014;171(16):3938-3945
Allosteric modulation of GluN2C/GluN2D-containing NMDA receptors bidirectionally modulates dopamine release: implication for Parkinson's disease
Zhang X; Feng Z-J; Chergui K
Article: EXPERIMENTAL NEUROLOGY. 2014;255:154-160
Allosteric modulation of NMDA receptors alters neurotransmission in the striatum of a mouse model of Parkinson's disease
Feng Z-J; Zhang X; Chergui K
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Alla övriga publikationer

Editorial: CURRENT OPINION IN PHARMACOLOGY. 2007;7(1):1-2
Many ways to Rome - multiple approaches to novel drugs
Chergui K; Fredholm BB; Svenningsson P
Review: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 1997;280(1):83-97
Neurochemical characteristics of amisulpride, an atypical dopamine D-2/D-3 receptor antagonist with both presynaptic and limbic selectivity
Schoemaker H; Claustre Y; Fage D; Rouquier L; Chergui K; Curet O; Oblin A; Gonon F; Carter C; Benavides J; Scatton B
Review: NEUROSCIENCE. 1996;72(1):141-156
Burst stimulation of the medial forebrain bundle selectively increases Fos-like immunoreactivity in the limbic forebrain of the rat
Chergui K; Nomikos GG; Mathe JM; Gonon F; Svensson TH

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