Juleen Zierath

Om mig
Publikationer
CV
Populärvetenskap och samverkan

Forskningsbeskrivning

Forskargruppsledare för gruppen Integrativ fysiologi vid institutionen för fysiologi och farmakologi och vid institutionen för molekylär medicin och kirurgi.

Artiklar

Article: CELL REPORTS MEDICINE. 2026;7(9):102988
Exercise intensity modulates interorgan communication and is associated with cardiometabolic health outcomes in humans
Olsen L; Botella J; Barrows D; Romero E; Baird K; Katayama M; Kilic E; Peralta C; Zanou N; Sanford H; Farrell L; Axelrod CL; Plucinska K; Walker J; Yan L; Fredrickson K; Pourquie O; Robbins JM; Vinogradova EV; Molina H; Place N; Kirwan JP; Zierath JR; Krook A; Gerszten RE; Bishop DJ; Cohen P
Review: TRENDS IN ENDOCRINOLOGY AND METABOLISM. 2026;37(9):868-879
Exercise timing and circadian regulation of metabolism in type 2 diabetes
Hansen SSK; Zierath JR; Wallberg-Henriksson H
Article: DIABETOLOGIA. 2026;69(6):1643-1658
Thromboxane signalling links immune activation to enhanced glucose uptake in skeletal muscle
Abdelmoez AM; Jollet M; Yu X; Rizo-Roca D; Marica AA; De Zevallos JO; Dollet L; Borg ML; Bjornholm M; Checa A; Olsson T; Otten J; Zierath JR; Krook A; Schwartz TW; Chibalin AV; Pillon NJ
Article: JOURNAL OF SPORT AND HEALTH SCIENCE. 2025;15:101098
Human development and gender inequality are associated with cardiorespiratory fitness: A global systematic review of VO2peak
Pillon NJ; de Zevallos JO; Zierath JR; Ainsworth BE
Article: JOURNAL OF SPORT AND HEALTH SCIENCE. 2025;15:101091
Exercise training-induced extracellular miR-136-3p modulates glucose uptake and myogenesis through targeting of NRDC in human skeletal muscle
Katayama M; Caria E; Van Simaeys D; Sanz AY; Barres R; Caidahl K; Wiklander OPB; El Andaloussi S; Berggren P-O; Zierath JR; Krook A
Article: DIABETOLOGIA. 2025;68(9):2023-2035
Inflammatory markers and blood glucose are higher after morning vs afternoon exercise in type 2 diabetes
Keller MJ; Brady AJ; Smith JAB; Savikj M; MacGregor K; Jollet M; Oberg SB; Nylen C; Bjornholm M; Rickenlund A; Carlsson M; Caidahl K; Krook A; Pillon NJ; Zierath JR; Wallberg-Henriksson H
Article: MOLECULAR METABOLISM. 2025;99:102200
Inactivity-induced NR4A3 downregulation in human skeletal muscle affects glucose metabolism and translation: Insights from in vitro analysis
Smith JAB; Gabriel BM; Brady AJ; Abdelmoez AM; Savikj M; Wright SC; Koutsilieri S; Barres R; Lauschke VM; Krook A; Zierath JR; Pillon NJ
Review: NATURE METABOLISM. 2025;7(9):1765-1780
A consensus guide to preclinical indirect calorimetry experiments
Banks AS; Allison DB; Alquier T; Austad SN; Auwerx J; Ayala JE; Baur JA; Carobbio S; Churchill GA; Dall M; de Cabo R; Donato J; Dragano NRV; Elias CF; Ferrante AW; Finck BN; Galgani JE; Gerhart-Hines Z; Goodyear LJ; Grobe JL; Gupta RK; Habegger KM; Hartig SM; Hevener AL; Heymsfield SB; Holman CD; de Angelis MH; James DE; Kazak L; Kim JB; Klingenspor M; Kong X; Kooijman S; Lantier L; Lloyd KCK; Lo JC; Lodhi IJ; Maclean PS; Mcguinness OP; Medina-Gomez G; Mirmira RG; Morrison CD; Morton GJ; Mueller TD; Ogawa Y; Pajuelo-Reguera D; Potthoff MJ; Qi N; Reitman ML; Rensen PCN; Rozman J; Rutkowsky JM; Sakamoto K; Scherer PE; Schwartz GJ; Sedlacek R; Selloum M; Shaikh SR; Chen S; Shulman GI; Skop V; Soukas AA; Speakman JR; Spiegelman BM; Steinberg GR; Svensson KJ; Thyfault JP; Tiganis T; Titchenell PM; Turner N; Velloso LA; Vidal-Puig A; Ward CS; Williams AS; Wolfrum C; Xu AW; Xu Y; Zierath JR
Article: MOLECULAR METABOLISM. 2025;98:102173
Training-induced plasma miR-29a-3p is secreted by skeletal muscle and contributes to metabolic adaptations to resistance exercise in mice
Pinto-Hernandez P; Fernandez-Sanjurjo M; Paget D; Caravia XM; Roiz-Valle D; Castilla-Silgado J; Diez-Robles S; Coto-Vilcapoma A; Fernandez-Vivero D; Gama-Perez P; Garcia-Roves PM; Lopez-Otin C; Zierath JR; Krook A; Fernandez-Garcia B; Tomas-Zapico C; Iglesias-Gutierrez E
Article: CELL. 2025;188(15):4106-4122.e16
Personalized molecular signatures of insulin resistance and type 2 diabetes
Kjaergaard J; Stocks B; Henderson J; Freemantle JB; Rizo-Roca D; Puglia M; Montoya MM; Andersson D; Backdahl J; Eriksson-Hogling D; Stidsen JV; Wierer M; Rasmussen S; Sakamoto K; Hojlund K; Ryden M; Zierath JR; Krook A; Deshmukh AS
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2025;122(28):e2504080122
HIF1α mediates circadian regulation of skeletal muscle metabolism and substrate preference in response to time-of-day exercise
Ehrlich AM; MacGregor KA; Ashcroft SP; Small L; Altintas A; Chibalin AV; Anagho-Mattanovich M; Stocks B; Moritz T; Treebak JT; Zierath JR
Article: SCIENCE ADVANCES. 2025;11(28):eads4371
Down-regulation of human-specific lncRNA TMEM9B-AS1 in skeletal muscle of people with type 2 diabetes affects ribosomal biogenesis
Sen I; Smith JAB; Caria E; Orlov I; Savikj M; Brady AJ; Lian K; Ellefsen S; Zierath JR; Krook A
Article: CELL METABOLISM. 2025;37(7):1460-1481.e17
NAD depletion in skeletal muscle does not compromise muscle function or accelerate aging
Chubanava S; Karavaeva I; Ehrlich AM; Justicia RM; Basse AL; Kulik I; Dalbram E; Ahwazi D; Heaselgrave SR; Trost K; Stocks B; Hodek O; Rodrigues RN; Havelund JF; Schlabs FL; Larsen S; Yonamine CY; Henriquez-Olguin C; Giustarini D; Rossi R; Gerhart-Hines Z; Moritz T; Zierath JR; Sakamoto K; Jensen TE; Faergeman NJ; Lavery GG; Deshmukh AS; Treebak JT
Article: CELL REPORTS MEDICINE. 2025;6(6):102163
Insulin-and exercise-induced phosphoproteomics of human skeletal muscle identify REPS1 as a regulator of muscle glucose uptake
Kjaergaard J; Lindqvist CB; Quesada JP; Jessen S; Schlabs F; Ehrlich AM; Yonamine CY; Garcia-Urena M; Schmalbruch JH; Small L; Thomassen M; Lemminger AK; Eibye K; Gonzalez-Franquesa A; Stidsen JV; Hojlund K; Zierath JR; Kilpelainen TO; Bangsbo J; Treebak JT; Hostrup M; Deshmukh AS
Review: JOURNAL OF INTERNAL MEDICINE. 2025;297(6):584-607
Metabolomics in cardiometabolic diseases: Key biomarkers and therapeutic implications for insulin resistance and diabetes
Rizo-Roca D; Henderson JD; Zierath JR
Article: MOLECULAR METABOLISM. 2025;95:102116
Enhanced metabolic adaptations following late dark phase wheel running in high-fat diet-fed mice
Ashcroft SP; Ehrlich AM; Burek K; Pendergrast LA; Yonamine CY; Treebak JT; Zierath JR
Review: NATURE METABOLISM. 2025;7(3):454-468
The time is now: accounting for time-of-day effects to improve reproducibility and translation of metabolism research
Deota S; Pendergast JS; Kolthur-Seetharam U; Esser KA; Gachon F; Asher G; Dibner C; Benitah SA; Escobar C; Muoio DM; Zhang EE; Hotamisligil GS; Bass J; Takahashi JS; Rabinowitz JD; Lamia KA; de Cabo R; Kajimura S; Longo VD; Xu Y; Lazar MA; Verdin E; Zierath JR; Auwerx J; Drucker DJ; Panda S
Article: MOLECULAR METABOLISM. 2025;92:102081
Exercise-induced methylation of the Serhl2 promoter and implication for lipid metabolism in rat skeletal muscle
Katayama M; Nomura K; Mudry JM; Chibalin AV; Krook A; Zierath JR
Article: SCIENCE ADVANCES. 2025;11(5):eadp8608
Temporal dynamics of the interstitial fluid proteome in human skeletal muscle following exhaustive exercise
Stocks B; Quesada JP; Mozzicato AM; Jacob C; Jensen S; Macgregor KA; Bangsbo J; Zierath JR; Hostrup M; Deshmukh AS
Article: SCIENCE TRANSLATIONAL MEDICINE. 2024;16(768):eado3022
Decreased mitochondrial creatine kinase 2 impairs skeletal muscle mitochondrial function independently of insulin in type 2 diabetes
Rizo-Roca D; Guimaraes DSPSF; Pendergrast LA; Di Leo N; Chibalin AV; Maqdasy S; Ryden M; Naslund E; Zierath JR; Krook A
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Alla övriga publikationer

Letter: NATURE METABOLISM. 2026;8(8):1623
Reclassification of basic experimental studies in humans - a case for a new publishing consensus
Richter EA; James DE; Kirwan JP; Zierath JR
Editorial: JOURNAL OF SPORT AND HEALTH SCIENCE. 2025;14:100980
Unlocking the secrets of exercise: A pathway to enhanced insulin sensitivity and skeletal muscle health in type 2 diabetes
Zierath JR; Brady AJ; Macgregor KA; de Zevallos JO; Stocks B
Editorial: DIABETOLOGIA. 2025;68(10):2083-2087
The moral equivalent: 60 years of publishing a scientific journal
Gale E; Alberti G; Ferrannini E; Marshall S; Zierath JR; Mulder H
Editorial: NATURE METABOLISM. 2025;7(8):1495-1497
Shaping the future of cardiometabolic innovation: advances and opportunities
Clemmensen C; Gerhart-Hines Z; Schwartz TW; Zierath JR; Sakamoto K
Editorial: CELL. 2024;187(15):3880-3884
Translating metabolic and cardiovascular research into effective treatments: What's next?
Zierath JR; van der Velden J; Javaheri A; Rosenzweig A; Muoio DM; Mulvihill EE; Martino TA; Rasheed A; Chen X-W; Arany ZP
Letter: CELL METABOLISM. 2024;36(5):882-883
Exploratory physiological experiments are not clinical trials
Richter EA; James DE; Kirwan JP; Zierath JR
Letter: NATURE REVIEWS ENDOCRINOLOGY. 2022;18(11):713
Reply to 'Lactate as a major myokine and exerkine'
Chow LS; Gerszten RE; Taylor JM; Pedersen BK; van Praag H; Trappe S; Febbraio MA; Galis ZS; Gao Y; Haus JM; Lanza IR; Lavie CJ; Lee C-H; Lucia A; Moro C; Pandey A; Robbins JM; Stanford KI; Thackray AE; Villeda S; Watt MJ; Xia A; Zierath JR; Goodpaster BH; Snyder M
Editorial: METABOLISM-CLINICAL AND EXPERIMENTAL. 2021;119:154769
COVID-19 editorial: mechanistic links and therapeutic challenges for metabolic diseases one year into the COVID-19 pandemic
Tessier CM; Kokkinos A; Mingrone G; Koliaki C; Zierath JR; Mantzoros CS
Corrigendum: NATURE COMMUNICATIONS. 2020;11(1):5142
Author Correction: Time-restricted feeding alters lipid and amino acid metabolite rhythmicity without perturbing clock gene expression.
Lundell LS; Parr EB; Devlin BL; Ingerslev LR; Altıntaş A; Sato S; Sassone-Corsi P; Barrès R; Zierath JR; Hawley JA
Editorial: CURRENT DIABETES REPORTS. 2019;19(11):118
Major Advances and Discoveries in Diabetes-2019 in Review
Zierath JR
Corrigendum: JOURNAL OF ENDOCRINOLOGY. 2019;243(2):X1
The estrogen receptor α-selective agonist propyl pyrazole triol improves glucose tolerance in ob/ob mice: potential molecular mechanisms (vol 199, pg 275, 2008)
Lundholm L; Bryzgalova G; Gao H; Portwood N; Falt S; Berndt KD; Dicker A; Galuska D; Zierath JR; Gustafsson J-A; Efendic S; Dahlman-Wright K; Khan A
Other: CELL METABOLISM. 2018;28(3):329
John O. Holloszy (1933-2018) Obituary
Zierath JR; Hagberg JM; Coyle EF
Corrigendum: SCIENTIFIC REPORTS. 2018;8(1):5008
Transcriptomic and epigenetic responses to short-term nutrient-exercise stress in humans (vol 7, 2017)
Laker RC; Garde C; Camera DM; Smiles WJ; Zierath JR; Hawley JA; Barres R
Editorial: CELL METABOLISM. 2017;25(5):978-984
Exercise Metabolism
Stanford K; Loos R; Evans R; Zierath JR; Leinwand LA; Rosenzweig A; Spiegelman B; Mott R; Helenius T; Febbraio MA; Weigert C; Goodpaster BH; Granger A; Panda S; Joyner MJ; Gibala M; Hawley J; Messmer-Blust A; Emambokus N
Editorial: CELL. 2016;167(5):1155-1158
Building Bridges through Scientific Conferences
Zierath JR
Editorial: CELL METABOLISM. 2016;24(2):342-342.e1
SnapShot: Exercise Metabolism
Egan B; Hawley JA; Zierath JR
Corrigendum: DIABETOLOGIA. 2015;58(12):2899
Turning the page (vol 58, pg 2685, 2015)
Zierath JR
Editorial: DIABETOLOGIA. 2015;58(12):2685-2687
Turning the page
Zierath JR
Editorial: DIABETOLOGIA. 2015;58(8):1685-1687
Diabetologia at 50: celebrating half a century of progress in diabetes research and care
Zierath JR
Editorial: CELL METABOLISM. 2015;21(5):654-657
Women in Metabolism: Part I
Kahn B; Simon MC; Zhang BB; Zierath JR; Muoio DM; Moore KJ; Cannon B; Haigis M; Schoonjans K; Mandrup S; Clement K; Andrews NC
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Anställningar

Professor, Klinisk integrativ fysiologi, Fysiologi och farmakologi, Karolinska Institutet, 2009-
Professor, Klinisk integrativ fysiologi, Molekylär medicin och kirurgi, Karolinska Institutet, 2006-
Professor, Klinisk integrativ fysiologi, Inst f kirurgisk vetenskap (K3), Karolinska Institutet, 2001-2005

Examina och utbildning

Docent, inriktning: fysiologi med inriktning metabolism, Karolinska Institutet, 1998

Forskningsbeskrivning

Artiklar

Alla övriga publikationer

Anställningar

Examina och utbildning

Nyheter från KI

Kalenderhändelser från KI