Jette Lengefeld

Publikationer
Forskningsbidrag
Populärvetenskap och samverkan

Artiklar

Journal article: JOURNAL OF EXPERIMENTAL MEDICINE. 2024;221(8):e20240971
Women in STEM becoming independent: Our shared motivation and enthusiasm are our driving force.
Andreeva L; Bosurgi L; Chong SZ; Chu C; Ge Y; Hoste E; Jurado KA; Lengefeld J; Mishra A; Wculek S; Young A
Journal article: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 2023;11:1219294
Editorial: Cell size regulation: molecular mechanisms and physiological importance
Lengefeld J; Zatulovskiy E
Journal article: BMC BIOLOGY. 2022;20(1):174
Segmentation, tracking and cell cycle analysis of live-cell imaging data with Cell-ACDC
Padovani F; Mairhoermann B; Falter-Braun P; Lengefeld J; Schmoller KM
Journal article: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 2022;10:1036602
Cellular enlargement-A new hallmark of aging?
Davies DM; van den Handel K; Bharadwaj S; Lengefeld J
Journal article: SCIENCE ADVANCES. 2021;7(46):eabk0271
Cell size is a determinant of stem cell potential during aging
Lengefeld J; Cheng C-W; Maretich P; Blair M; Hagen H; McReynolds MR; Sullivan E; Majors K; Roberts C; Kang JH; Steiner JD; Miettinen TP; Manalis SR; Antebi A; Morrison SJ; Lees JA; Boyer LA; Yilmaz OH; Amon A
Journal article: EXPERIMENTAL HEMATOLOGY. 2021;100:s54
3022 – CELL SIZE IS A DETERMINANT OF STEM CELL POTENTIAL DURING AGING
Lengefeld J; Amon A
Journal article: CELL. 2019;176(5):1083-1097.e18
Excessive Cell Growth Causes Cytoplasm Dilution And Contributes to Senescence
Neurohr GE; Terry RL; Lengefeld J; Bonney M; Brittingham GP; Moretto F; Miettinen TP; Vaites LP; Soares LM; Paulo JA; Harper JW; Buratowski S; Manalis S; van Werven FJ; Holt LJ; Amon A
Journal article: BIOESSAYS. 2018;40(8):e1800038
Asymmetric Segregation of Aged Spindle Pole Bodies During Cell Division: Mechanisms and Relevance Beyond Budding Yeast?
Lengefeld J; Barral Y
Journal article: MOLECULAR BIOLOGY OF THE CELL. 2018;29(1):10-28
Spatial cues and not spindle pole maturation drive the asymmetry of astral microtubules between new and preexisting spindle poles
Lengefeld J; Yen E; Chen X; Leary A; Vogel J; Barral Y
Journal article: NATURE CELL BIOLOGY. 2017;19(8):941-951
Budding yeast Wee1 distinguishes spindle pole bodies to guide their pattern of age-dependent segregation
Lengefeld J; Hotz M; Rollins M; Baetz K; Barral Y
Journal article: PLOS GENETICS. 2015;11(2):e1004938
Asymmetry of the Budding Yeast Tem1 GTPase at Spindle Poles Is Required for Spindle Positioning But Not for Mitotic Exit
Scarfone I; Venturetti M; Hotz M; Lengefeld J; Barral Y; Piatti S
Journal article: JOURNAL OF BIOTECHNOLOGY. 2014;191:214-220
The nucleotide composition of the spacer sequence influences the expression yield of heterologously expressed genes in Bacillus subtilis
Liebeton K; Lengefeld J; Eck J
Journal article: PLOS BIOLOGY. 2014;12(2):e1001793
Cecum Lymph Node Dendritic Cells Harbor Slow-Growing Bacteria Phenotypically Tolerant to Antibiotic Treatment
Kaiser P; Regoes RR; Dolowschiak T; Wotzka SY; Lengefeld J; Slack E; Grant AJ; Ackermann M; Hardt W-D
Journal article: CELL CYCLE. 2012;11(16):3109-3116
The MEN mediates the effects of the spindle assembly checkpoint on Kar9-dependent spindle pole body inheritance in budding yeast
Hotz M; Lengefeld J; Barral Y
Journal article: PLOS ONE. 2012;7(4):e34812
Salmonella Transiently Reside in Luminal Neutrophils in the Inflamed Gut
Loetscher Y; Wieser A; Lengefeld J; Kaiser P; Schubert S; Heikenwalder M; Hardt W-D; Stecher B

Alla övriga publikationer

Preprint: BIORXIV. 2024
SpotMAX: a generalist framework for multi-dimensional automatic spot detection and quantification
Padovani F; Čavka I; Neves ARR; López CP; Al-Refaie N; Bolcato L; Chatzitheodoridou D; Chadha Y; Su XA; Lengefeld J; Cabianca DS; Köhler S; Schmoller KM
Preprint: BIORXIV. 2021
Cell-ACDC: a user-friendly toolset embedding state-of-the-art neural networks for segmentation, tracking and cell cycle annotations of live-cell imaging data
Padovani F; Mairhörmann B; Falter-Braun P; Lengefeld J; Schmoller KM
Preprint: BIORXIV. 2020
Cell size is a determinant of stem cell potential during aging
Lengefeld J; Cheng C-W; Maretich P; Blair M; Hagen H; McReynolds MR; Sullivan E; Majors K; Roberts C; Kang JH; Steiner JD; Miettinen TP; Manalis SR; Antebi A; Morrison SJ; Lees JA; Boyer LA; Yilmaz ÖH; Amon A

Forskningsbidrag

Cell size as driver of stem cell aging and cancer
European Research Council (ERC) - Starting Grant
1 January 2024 - 31 December 2028
Size as a driver of stem cell ageing and cancer
Swedish Research Council
1 January 2023 - 31 December 2026
Centre of Excellence in Stem Cell Metabolism
Academy of Finland
13 December 2022 - 31 December 2025
Jeanssons Stiftelser
1 January 2022 - 31 December 2023
Investigating Cellular and Molecular Signals in Leukemia Initiation
Cancer Foundation Finland
23 November 2021
Impact of cell size in regulating stem cell function during aging and disease
Academy of Finland
3 May 2021 - 31 August 2026
Investigating niche- and hematopoietic-derived signals in leukemia initiation. Verisolujen sekä mikroympäristön välittämien signaalien kartoittaminen leukemian synnyssä.
Cancer Foundation Finland
10 November 2020
Implications of changes in cellular size on cell division and aging
Jane Coffin Childs Memorial Fund for Medical Research
1 July 2018 - 30 June 2021
Identification of mTORC1-dependent mechanisms driving senescence
Swiss National Science Foundation
1 January 2017 - 30 June 2018
Mechanism of centrosome specification
Swiss National Science Foundation
1 December 2013 - 30 November 2016
Mechanism and Function of Spindle Asymmetry
Swiss National Science Foundation
1 January 2010 - 30 June 2013

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