Ghada Nouairia
Biträdande Lektor
E-postadress: ghada.nouairia@ki.se
Besöksadress: Karolinska Universitetssjukhuset Huddinge, C177, 14186 Huddinge
Postadress: H7 Medicin, Huddinge, H7 GUT Bergquist, 171 77 Stockholm
Om mig
Bioinformatician and computational biologist with a background in biology.
I am a PhD in molecular genetics since 2018 (Carthage University, Tunisia). Driven by curiosity, I moved to explore molecular evolution as a computational biologist in Stockholm University. Now I redirected her skills to the exciting field of clinical research with focus on multiomics data
analysis of Primary Sclerosing Colangitis (PSC).
I am also part of the Center for Bioinformatics and Biostatistics (CBB) where I redirect my bioinformatic skills to mentoring and helping others. If you
need help with bioinformatics or biostatistics, please visit our website (see links section).
(2018) PhD in molecular genetics from Carthage university, Tunisia
(2013) Master degree in animal genetics from Carthage university, Tunisia.
(2010) Engineering degree from Carthage university, Tunisia.
Forskningsbeskrivning
- Primary sclerosing cholangitis (PSC) is a rare disease of the bile duct. Patients with PSC are very susceptible to develop malignancy (especially
cholangiocarcinoma and colorectal cancer). We analyse and integrate different types of omics data in order to find new biomarkers for diagnosis and
prognosis purposes. We also seek to understand the underlying biology and pathways of the disease.
Utvalda publikationer
- Article: JHEP REPORTS. 2026;8(3):101719Cornillet M; Bave AL; Sun D; Nouairia G; Villard C; Grigoriadis A; Von Seth E; Jansson H; Alvez MB; Bergstrom S; Nilsson P; Uhlen M; Edfors F; Stal P; Sparrelid E; Bjorkstrom NK; Halfvarson J; Bergquist A
- Article: EJSO. 2025;51(8):110123Akiki A; Jacobsson H; Nouairia G; Cornillet M; Björkström NK; Sparrelid E; Taflin H; Jansson H
- Article: JHEP REPORTS. 2025;7(6):101365Nouairia G; Cornillet M; Jansson H; Bergquist A; Sparrelid E
- Journal article: JOURNAL OF HEPATOLOGY. 2025;82:s421-s422Zenlander R; Nouairia G; Shtembari S; Hagey D; Danielsson O; Bjornstedt M; Gilg S; Eggertsen G; Salter H; Stal P
- Article: SCIENTIFIC REPORTS. 2024;14(1):19656Jungholm O; Trkulja C; Moche M; Srinivasa SP; Christakopoulou M-N; Davidson M; Reymer A; Jardemark K; Fogaca RL; Ashok A; Jeffries G; Ampah-Korsah H; Strandback E; Andrell J; Nyman T; Nouairia G; Orwar O
Artiklar
- Journal article: ANNALS OF ONCOLOGY. 2024;35:S134Nouairia G; Cornillet M; Jansson H; Bergquist A; Sparrelid E
- Article: NATURE COMMUNICATIONS. 2022;13(1):2700Rozman Grinberg I; Martínez-Carranza M; Bimai O; Nouairia G; Shahid S; Lundin D; Logan DT; Sjöberg B-M; Stenmark P
- Article: GENES. 2022;13(2):304Ben Sassi-Zaidy Y; Mohamed-Brahmi A; Nouairia G; Charfi-Cheikhrouha F; Djemali M; Cassandro M
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2021;297(2):101008Schell E; Nouairia G; Steiner E; Weber N; Lundin D; Loderer C
- Article: JOURNAL OF NEW SCIENCES. 2018;7Nouairia G; Cassandro M; Ben larbi M; Viale E; Hammadi M; Yahyaoui MH
- Article: EMIRATES JOURNAL OF FOOD AND AGRICULTURE. 2015;27(4):362Nouairia G; Kdidi S; Ben Salah R; Hammadi M; Khorchani T; Yahyaoui MH
- Article: JOURNAL OF NEW SCIENCES. 2014;5(https://www.jnsciences.org/agri-biotech/13-volume-5/20-etude-technico-economique-de-methodes-d-extraction-de-l-adn-chez-le-lapin-europeen-oryctolagus-cuniculus-a-partir-du-sang.html)Nouairia G; Belarbi M; Yahyaoui MH; Hadded B
Alla övriga publikationer
- Corrigendum: EJSO. 2026;52(1):111189Akiki A; Jacobsson H; Nouairia G; Cornillet M; Bjorkstrom NK; Sparrelid E; Taflin H; Jansson H
- Conference publication: JOURNAL OF HEPATOLOGY. 2025;82Zenlander R; Nouairia G; Shtembari S; Hagey D; Danielsson O; Bjornstedt M; Gilg S; Eggertsen G; Salter H; Stal P
- Conference publication: HPB. 2025;27:s293Jansson H; Akiki A; Jacobsson H; Nouairia G; Cornillet M; Björkström NK; Taflin H; Sparrelid E
- Preprint: MEDRXIV. 2024Akiki A; Jacobsson H; Nouairia G; Cornillet M; Björkström NK; Sparrelid E; Taflin H; Jansson H
- Poster: HTTPS://WWW.IPSCSG.ORG/NEWS/SAVE-THE-DATE-FOR-THE-IPSCSG-BIENNIAL-MEETING-IN-STOCKHOLM-2024/. 2024Machine-learning based multi-OMICs analysis of circulome from Primary Sclerosing Cholangitis reveals hallmarks associated with cholangiocarcinoma and absence of inflammatory bowel diseaseNouairia G; Cornillet M; Bergquist A
- Conference publication: BJS-BRITISH JOURNAL OF SURGERY. 2024;111:znae175.019Akiki A; Jacobsson H; Nouairia G; Cornillet M; Bjorkstrom NK; Sparrelid E; Taflin H; Jansson H
- Poster: HTTPS://WWW.OSTI.GOV/SERVLETS/PURL/1558092. 2019Class Id MnIVMnIII ribonucleotide reductase from Facklamia ignavaRozman-Grinberga I; Nouairia G; Lundin D; Sjöberg B-M
- Doctoral thesis: 2018Nouairia G; Yahyaoui MH; Hadded B
- Meeting abstract: HTTPS://WWW.RESEARCHGATE.NET/PUBLICATION/272291464_GENETIC_VARIABILITY_OF_DROMEDARY_CAMEL_IN_TUNISIA_PRELIMINARY_RESULTS. 2014;1Nouairia G; Yahyaoui MH; Khorchani B
- Meeting abstract: HTTPS://PPS.KAZNU.KZ/KZ/MAIN/FILESHOW2/39771/76/3/700/0//. 2013;p63-64(2013):63-64Nouairia G; Yahyaoui MH; Khorchani T
- Licentiate thesis: 2013Nouairia G; Yahyaoui MH; Hadded B
- Licentiate thesis: 2010Nouairia G; Belarbi M; Hadded B
Utvalda forskningsbidrag
- Ruth och Richard Julins stiftelse14 March 2024 - 14 March 2025
Forskningsbidrag
- Nya biologiska markörer för gallgångscancer, gallblåserscancer och primär skleroserande kolangitMag-Tarmfonden1 March 2023Gallgångscancer (CCA) och gallblåserscancer (GBC) är mycket aggressiva former av cancer som är vanligtvis mycket sent upptäkt och har dålig prognos. Förhöjd risk för CCA och GBC är mestadels oförklarlig och studier som förklara riskfaktorerna behövs. Primär skleroserande kolangit (PSC) är en kronisk progressiv leversjukdom med hög risk för gallgångsrelaterad cancer (15-20%). PSC har ingen känd behandling som kan bromsar sjukdomsutveckling eller minskar cancerrisk. PSC patienter kan fungera som en modell för att studera populationer med hög risk för CCA och GBC. Markörer för tidig cancerutveckling och prognos saknas för de här sjukdomar. Den här forskningsprogrammet söker nya markörer för tidig cancerdiagnostik och sjukdomrogress hos patienter med hög risk för CCA och GBC och för att hjälpa till vid beslutsfattandet om kirurgiskt avlägsnande av tumören. Den identifierar också biologiska mekanismer som påverkas gallgångs sjukdomar.
Anställningar
- Biträdande Lektor, Medicin, Huddinge, Karolinska Institutet, 2024-2030
- Postdoktor, Medicin, Huddinge, Karolinska Institutet, 2022-2024
- Researcher, Bioinformatics and computational biology, DBB, Stockholm University, 2021-2021
Examina och utbildning
- Teaching and Learning in Higher Education (GHPD), Karolinska Institutet, 2025
- Career development program in MEDH, Department of Medicine, Huddinge, Karolinska Institutet, 2024
- Fellows in Gender Equal Career Development, Gender equality, equal opportunities, leadership, academic citizenship, LIME, Karolinska Institutet, 2024
- Introduction to Python – with application to bioinformatics, Programming, Bioinformatics, NBIS – National Bioinformatics Infrastructure Sweden, 2024
- Biomarker Discovery: from theory to real world examples, NBIS – National Bioinformatics Infrastructure Sweden, 2024
- Cancer Core Europe Summer School in translational cancer research, Translational cancer research, Cancer Core Europe, 2024
- Train the trainer course, SciLifeLab, 2024
- Web Course for Doctoral Supervisors, Academic supervision, Karolinska Institutet, 2024
- Code Refinery course series (online), Coding, programming, bash, University of Oslo, 2023
- Course in Neural Networks and Deep Learning, Artificial Intelligence, National Bioinformatics Infrastructure, Sweden, 2023
- Interenational course in Bioinformatics and Genomics (MSc. Equivalent), Bioinformatics and genomics, Institut Pasteur de Tunis, 2018
- PhD in Genetics, Molecular and population genetics, Genetic characterization of Dromedary camel population in Tunisia, Agronomy and Animal husbandry, University of Carthage, 2018
- Master degree in Animal Genetics, Animal genetics and reproduction, Cross species validation of genetic markers, University of Carthage, 2013
- Engineering degree in Animal genetics, Animal genetics, Comparison of DNA extraction methods, University of Carthage, 2010
Priser och utmärkelser
- Top student in the International course for Bioinformatics and genomics, Full grades (20 points over 20) and top student (not shared), Institut Pasteur de Tunis, 2018
- PhD validation with Very honorable distinction with the board’s congratulations, Very honorable distinction” with “the board’s congratulations” is the highest distinction for PhD dissertation in Tunisia, Université Tunis Carthage, 2018
- MSc. dissertation with First class honor, First class honor is the highest appreciation for master degree dissertations ranked 1st/31 for the class and 1st/80 in all master degree classes, Université Tunis Carthage, 2013
Handledning
Uppdrag i kommitté
- Medlem, Organisation committee for the Bioinformaticians network, Karolinska Institutet, 2024-
- Medlem, Organising committee for the Gastro-MedH research day, department of medicine, Karolinska Institutet, 2024-2024
- Medlem, Forskarutbuildningsnämnden, Institutionen för Medicin, Huddinge, Karolinska Institutet, 2024-
- Medlem, European Cooperation in Science and Technology (COST), Precision medicine in biliary tract cancer (Precision-BTC-Network), European Cooperation in Science and Technology, 2024-
Gästforskning och resestipendier
- Wenner-Gren International Postdoc fellowship, Stockholm University, Biochemical and bioinformatics characterization of Ribonucleotide Reductase protein family in the tree of life, 2018-2020
- Excellence scholarship for PhD students, University of Veterinary Medicine Vienna, 2 months of internship in bioinformatics and population genetics, 2016-2016
- Erasmus Mundus, University of Padua, 6 months scholarship for PhD studies, 2015-2016
- Excellence scholarship for PhD students, Friedrich-Loeffler-Institut, 2 months of internship in bioinformatics and R programming, 2015-2015
Sakkunniggranskning för vetenskaplig tidskrift
Expert
- Annat bedömningsuppdrag, Unga forskare, Förbundet Unga Forskare, 2025-2025
Konferenser och events
- Inbjuden föredragshållare, Novel tools in biomedical research, Organized by Pr. Mohamed Jemaa from the faculty of Medicine (Tunis, Tunisia), previously affiliated to Lund University, Sweden., Entering the omics era: Is it optional?, 2025
- Inbjuden föredragshållare, AI in biomedical research, Machine Learning and Neural Networks in clinical research, 2025
- Muntlig presentation av inskickat abstract, International PSC Study Group biannual conference, Stockholm, Sweden, 2024, Genome-wide methylation profiling of biliary tract cancers reveals pathogenesis mechanisms and clinical applications, 2024
- Poster-presentation av inskickat abstract, International IPSCSG BIENNIAL MEETING IN STOCKHOLM 2024!, Machine-learning based multi-OMICs analysis of circulome from Primary Sclerosing Cholangitis reveals hallmarks associated with cholangiocarcinoma and absence of inflammatory bowel disease, 2024
- Poster-presentation av inskickat abstract, ESMO Gastrointestinal cancers, Munich, Germany, 2024, new%20data%20in%20GI%20oncology., Serum based test to assist preoperative decision making in suspected gallbladder cancer, https://linkinghub.elsevier.com/retrieve/pii/S092375342400601X, 2024
- Muntlig presentation av inskickat abstract, Collaboration in Science conference, Serum based test to assist preoperative decision making in suspected gallbladder cancer, 2024
- Deltagare, EASL, 2024
- Muntlig presentation av inskickat abstract, Elixir Denmark-Danish bioinformatics conference, Aarhus, Denmark. 2023, tools%20development%20in%20Danish%20bioinformatics., Feature selection for omics-based biomarkers in rare diseases, 2023
- Muntlig presentation av inskickat abstract, Mayo clinics - Karolinska Institutet joint conference, Rochester, USA. 2023, Genome-wide methylation profiling of biliary tract cancers reveals pathogenesis mechanisms and clinical applications, https://ki.se/en/collaboration/international-collaboration/the-mayo-clinic-and-karolinska-institutet-collaboration/the-mayo-ki-annual-scientific-research-meeting-2023, 2023
- Muntlig presentation av inskickat abstract, Svenska Gastrodagarna, Protein biomarker för precis preopertiv diagnos av gallblåscancer, 2022
- Muntlig presentation av inskickat abstract, Collaboration in Science, Using Genome-scale DNA Methylation in Clinical Oncology, 2022
- Poster-presentation av inskickat abstract, Metals in Biology Gordon research conference. California, USA. 2018, Class Id MnIVMnIII ribonucleotide reductase from Facklamia ignava, https://www.osti.gov/servlets/purl/1558092, 2019
- Muntlig presentation av inskickat abstract, International scientific conference of camel research and production, Al-Khartoum, Sudan. 2017, History and genetic variability of dromedary camel (Camelus dromedarius) revealed by mitochondrial DNA, 2017
- Muntlig presentation av inskickat abstract, International Seminar on Livestock and Wild animals in Arid lands and Desert. Tunisia, 2014, Genetic variability of Camelus dromedarius population in Tunisia using microsatellite markers, http://10.0.51.84/2.1.3195.7282, 2014
- Poster-presentation av inskickat abstract, International conference on Sustainability of Camel population and Production. King Faisal University Al-Hasa, Saudi Arabia, 2013, Amplification of alpaca tetranucleotide microsatellite markers in dromedary camel (Camelus dromedarius), http://10.0.51.84/2.1.2409.2965, 2013
Nyheter från KI
Kalenderhändelser från KI
Presentationer
- Presentation (slides etc.): 2024Nouairia G; Cornillet M; Bergquist A
- Presentation (slides etc.): 2023Nouairia G; Cornillet M; Bergquist A
- Presentation (slides etc.): 2023Nouairia G; Cornillet M; Bergquist A