Ghada Nouairia

Computational oncologist and bioinformatician with focus on hepato-biliary disorders and cancers. 
With a background in engineering, a PhD in molecular genetics since 2018 (Carthage University, Tunisia) and a master degree equivalent in Bioinformatics and genomics (Institut Pasteur), I have innovative, interdisciplinary solutions to medical and translational research questions. Specifically, I apply computational methods, including machine learning, deep learning and neural networks in disease modelling and biomarker discovery for different types of cancers (cholangiocarcinoma and gallladder cancer) and liver disorders such as primary sclerosing cholangitis, using multiomics data analysis (namely epigenomics, proteomics, metabolomics, auto-antibodies and expression data).

Previously, I explored computational and molecular evolution in Stockholm University where I studied the evolution and the diversity of a key protein family (riboluncleotide reductases: RNRs) in the tree of life. I also studied genomics and population genetics in animal species.

I am also part of the Center for Bioinformatics and Biostatistics (CBB) where I offer mentoring and consulting in bioinformatics and computational methods for PhD students and researchers. I am as well involved in many teaching activities at CBB including educational seminars and workshops.

Since January 2024, I am part of the Forskarutbildningsnämnd board at KI.

I am a member of the COST Network (Bile Tract Cancer precision medicine action) and ESMO society. In KI, I am part of the cancer research, the bioinformaticians, and the WISE (Women In Science and Education) networks.

Reading is my drug and I am eagerly interested in science, psychology, history, politics (and much more) and I am hungry to share and have discussions on these subjects!

Primary sclerosing cholangitis (PSC) is a chronic liver disease with the dramatic outcomes of premature death, liver transplantation or malignancy development (cholangiocarcinoma CCA, colorectal cancer CRC, hepatocellular carcinoma HCC, or Gallbladder cancer GBC). Unfortunately, Scandinavia is the most touched area in the world. The underlying pathophysiologic mechanisms of PSC and other Biliary Tract Cancers (BTC) are poorly understood and the ability to diagnose them early and to predict their progression is crucial.
We aim to contribute to the understanding of these -often- related disorders and to develop clinical tools for diagnosis, prognosis and monitoring of these diseases, by combining long clinical experience and the promising multiomics technologies.