Konstantinos Meletis

Om mig
Publikationer
CV
Populärvetenskap och samverkan

Om mig

Konstantinos Meletis är professor i systemneurovetenskap vid institutionen för neurovetenskap.

Utvalda akademiska priser och utmärkelser
- 2024 – Arvid Carlsson Fondens pris
- 2015 – William K. Bowes Jr. Foundation Associate Professor Award
- 2013 – Framtidens Forskningsledare, FFL5, Stiftelsen för Strategisk Forskning
- 2011 – William K. Bowes Jr. Foundation Assistant Professor Award
- 2010 – Marie Curie Reintegration Grant FP7 (EU)
- 2010 – NARSAD Young Investigator Award (USA)

Artiklar

Article: NATURE COMMUNICATIONS. 2025;16(1):812
Syngap1 promotes cognitive function through regulation of cortical sensorimotor dynamics
Vaissiere T; Michaelson SD; Creson T; Goins J; Furth D; Balazsfi D; Rojas C; Golovin R; Meletis K; Miller CA; O'Connor D; Fontolan L; Rumbaugh G
Article: CURRENT BIOLOGY. 2024;34(22):5263-5283.e8
Striosomes control dopamine via dual pathways paralleling canonical basal ganglia circuits
Lazaridis I; Crittenden JR; Ahn G; Hirokane K; Wickersham IR; Yoshida T; Mahar A; Skara V; Loftus JH; Parvataneni K; Meletis K; Ting JT; Hueske E; Matsushima A; Graybiel AM
Article: BIORXIV. 2024;:2023.09.27.559787
Syngap1 Promotes Cognitive Function through Regulation of Cortical Sensorimotor Dynamics.
Vaissiere T; Michaelson SD; Creson T; Goins J; Fürth D; Balazsfi D; Rojas C; Golovin R; Meletis K; Miller CA; O'Connor D; Fontolan L; Rumbaugh G
Article: NATURE COMMUNICATIONS. 2024;15(1):4778
Spatially resolved multiomics on the neuronal effects induced by spaceflight in mice
Masarapu Y; Cekanaviciute E; Andrusivova Z; Westholm JO; Bjorklund A; Fallegger R; Badia-i-Mompel P; Boyko V; Vasisht S; Saravia-Butler A; Gebre S; Lazar E; Graziano M; Frapard S; Hinshaw RG; Bergmann O; Taylor DM; Wallace DC; Sylven C; Meletis K; Saez-Rodriguez J; Galazka JM; Costes SV; Giacomello S
Article: ISCIENCE. 2024;27(5):109743
Cell-type-specific representation of spatial context in the rat prefrontal cortex
Brunner H; Kim H; Ahrlund-Richter S; van Lunteren JA; Crestani AP; Meletis K; Carlen M
Article: ENEURO. 2023;10(7):1-20
A Selective Projection from the Subthalamic Nucleus to Parvalbumin-Expressing Interneurons of the Striatum
Kondabolu K; Doig NM; Ayeko O; Khan B; Torres A; Calvigioni D; Meletis K; Koos T; Magil PJ
Article: NATURE NEUROSCIENCE. 2023;26(7):1245-1255
Esr1⁺ hypothalamic-habenula neurons shape aversive states
Calvigioni D; Fuzik J; Le Merre P; Slashcheva M; Jung F; Ortiz C; Lentini A; Csillag V; Graziano M; Nikolakopoulou I; Weglage M; Lazaridis I; Kim H; Lenzi I; Park H; Reinius B; Carlen M; Meletis K
Article: NUCLEIC ACIDS RESEARCH. 2023;51(8):e47
The spatial landscape of gene expression isoforms in tissue sections
Lebrigand K; Bergenstrahle J; Thrane K; Mollbrink A; Meletis K; Barbry P; Waldmann R; Lundeberg J
Article: CELL REPORTS. 2021;36(4):109437
Complete representation of action space and value in all dorsal striatal pathways
Weglage M; Warnberg E; Lazaridis I; Calvigioni D; Tzortzi O; Meletis K
Article: PLOS BIOLOGY. 2021;19(7):e3001341
Assessing the replicability of spatial gene expression using atlas data from the adult mouse brain
Lu S; Ortiz C; Furth D; Fischer S; Meletis K; Zador A; Gillis J
Article: JOURNAL OF NEUROSCIENCE. 2021;41(14):3120-3141
Adult trkB Signaling in Parvalbumin Interneurons is Essential to Prefrontal Network Dynamics.
Guyon N; Zacharias LR; van Lunteren JA; Immenschuh J; Fuzik J; Märtin A; Xuan Y; Zilberter M; Kim H; Meletis K; Lopes-Aguiar C; Carlén M
Article: NATURE COMMUNICATIONS. 2021;12(1):1026
Distinct subtypes of proprioceptive dorsal root ganglion neurons regulate adaptive proprioception in mice
Wu H; Petitpre C; Fontanet P; Sharma A; Bellardita C; Quadros RM; Jannig PR; Wang Y; Heimel JA; Cheung KKY; Wanderoy S; Xuan Y; Meletis K; Ruas J; Gurumurthy CB; Kiehn O; Hadjab S; Lallemend F
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2019;116(51):25958-25967
Brain-wide genetic mapping identifies the indusium griseum as a prenatal target of pharmacologically unrelated psychostimulants
Fuzik J; Rehman S; Girach F; Miklosi AG; Korchynska S; Arque G; Romanov RA; Hanics J; Wagner L; Meletis K; Yanagawa Y; Kovacs GG; Alpar A; Hokfelt TGM; Harkany T
Article: NATURE NEUROSCIENCE. 2019;22(4):657-668
A whole-brain atlas of monosynaptic input targeting four different cell types in the medial prefrontal cortex of the mouse
Ahrlund-Richter S; Xuan Y; van Lunteren JA; Kim H; Ortiz C; Dorocic IP; Meletis K; Carlen M
Article: JOURNAL OF COMPARATIVE NEUROLOGY. 2017;525(15):3227-3250
Monosynaptic retrograde tracing of neurons expressing the G-protein coupled receptor Gpr151 in the mouse brain
Broms J; Grahm M; Haugegaard L; Blom T; Meletis K; Tingstrom A
Article: CELL RESEARCH. 2016;26(9):1033-1047
Cortical neurons gradually attain a post-mitotic state
de Anda FC; Madabhushi R; Rei D; Meng J; Graeff J; Durak O; Meletis K; Richter M; Schwanke B; Mungenast A; Tsai L-H
Article: NATURE. 2012;489(7414):150-154
Neuronal circuitry mechanism regulating adult quiescent neural stem-cell fate decision
Song J; Zhong C; Bonaguidi MA; Sun GJ; Hsu D; Gu Y; Meletis K; Huang ZJ; Ge S; Enikolopov G; Deisseroth K; Luscher B; Christian KM; Ming G-L; Song H
Article: NATURE NEUROSCIENCE. 2012;15(7):1022-1031
Autism spectrum disorder susceptibility gene TAOK2 affects basal dendrite formation in the neocortex
de Anda FC; Rosario AL; Durak O; Tran T; Graeff J; Meletis K; Rei D; Soda T; Madabhushi R; Ginty DD; Kolodkin AL; Tsai L-H
Article: MOLECULAR PSYCHIATRY. 2012;17(5):537-548
A critical role for NMDA receptors in parvalbumin interneurons for gamma rhythm induction and behavior
Carlen M; Meletis K; Siegle JH; Cardin JA; Futai K; Vierling-Claassen D; Ruehlmann C; Jones SR; Deisseroth K; Sheng M; Moore CI; Tsai L-H
Article: ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY. IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY. ANNUAL INTERNATIONAL CONFERENCE. 2011;2011:7529-7532
Chronically Implanted Hyperdrive for Cortical Recording and Optogenetic Control in Behaving Mice
Siegle JH; Carlen M; Meletis K; Tsai L-H; Moore CI; Ritt J
Article: CELL STEM CELL. 2010;7(4):470-482
Origin of New Glial Cells in Intact and Injured Adult Spinal Cord
Barnabe-Heider F; Goritz C; Sabelstrom H; Takebayashi H; Pfrieger FW; Meletis K; Frisen J
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2010;107(33):14657-14661
Efficient reprogramming of adult neural stem cells to monocytes by ectopic expression of a single gene
Forsberg M; Carlen M; Meletis K; Yeung MSY; Barnabe-Heider F; Persson MAA; Aarum J; Frisen J
Article: JOURNAL OF NEUROSCIENCE. 2010;30(31):10391-10406
Centrosome Motility Is Essential for Initial Axon Formation in the Neocortex
de Anda FC; Meletis K; Ge X; Rei D; Tsai L-H
Article: NEURON. 2010;67(1):33-48
Dixdc1 Is a Critical Regulator of DISC1 and Embryonic Cortical Development
Singh KK; Ge X; Mao Y; Drane L; Meletis K; Samuels BA; Tsai L-H
Article: BRAIN. 2010;133(Pt 4):983-995
A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2α
Seidel S; Garvalov BK; Wirta V; von Stechow L; Schaenzer A; Meletis K; Wolter M; Sommerlad D; Henze A-T; Nister M; Reifenberger G; Lundeberg J; Frisen J; Acker T
Article: NATURE PROTOCOLS. 2010;5(2):247-254
Targeted optogenetic stimulation and recording of neurons in vivo using cell-type-specific expression of Channelrhodopsin-2
Cardin JA; Carlen M; Meletis K; Knoblich U; Zhang F; Deisseroth K; Tsai L-H; Moore CI
Article: NATURE. 2009;459(7247):663-U63
Driving fast-spiking cells induces gamma rhythm and controls sensory responses
Cardin JA; Carlen M; Meletis K; Knoblich U; Zhang F; Deisseroth K; Tsai L-H; Moore CI
Article: NATURE NEUROSCIENCE. 2009;12(3):259-267
Forebrain ependymal cells are Notch-dependent and generate neuroblasts and astrocytes after stroke
Carlen M; Meletis K; Goritz C; Darsalia V; Evergren E; Tanigaki K; Amendola M; Barnabe-Heider F; Yeung MSY; Naldini L; Honjo T; Kokaia Z; Shupliakov O; Cassidy RM; Lindvall O; Frisen J
Article: PLOS BIOLOGY. 2008;6(7):e182-1507
Spinal cord injury reveals multilineage differentiation of ependymal cells
Meletis K; Barnabe-Heider F; Carlen M; Evergren E; Tomilin N; Shupliakov O; Frisen J
Article: NATURE METHODS. 2008;5(2):189-196
Genetic manipulation of adult mouse neurogenic niches by in vivo electroporation
Barnabe-Heider F; Meletis K; Eriksson M; Bergmann O; Sabelstrom H; Harvey MA; Mikkers H; Frisen J
Article: DEVELOPMENTAL DYNAMICS. 2007;236(6):1663-1676
Ablation of de novo DNA methyltransferase dnmt3a in the nervous system leads to neuromuscular defects and shortened lifespan
Nguyen' S; Meletis K; Fu D; Jhaveri S; Jaenisch R
Article: EXPERIMENTAL CELL RESEARCH. 2006;312(15):2851-2859
Genetic visualization of neurogenesis
Carlen M; Meletis K; Barnabe-Heider F; Frisen J
Article: EXPERIMENTAL CELL RESEARCH. 2006;312(10):1798-1812
Catalog of gene expression in adult neural stem cells and their in vivo microenvironment
Williams C; Wirta V; Meletis K; Wikstrom L; Carlsson L; Frisen J; Lundeberg J
Article: MOLECULAR AND CELLULAR BIOLOGY. 2006;26(8):2976-2983
Suppression of intestinal neoplasia by deletion of Dnmt3b
Lin HJ; Yamada Y; Nguyen S; Linhart H; Jackson-Grusby L; Meissner A; Meletis K; Lo G; Jaenisch R
Article: DEVELOPMENT. 2006;133(2):363-369
P53 suppresses the self-renewal of adult neural stem cells
Meletis K; Wirta V; Hede SM; Nistér M; Lundeberg J; Frisén J
Article: DEVELOPMENTAL NEUROSCIENCE. 2006;28(1-2):118-127
Recording Notch signaling in real time
Hansson EM; Teixeira AI; Gustafsson MV; Dohda T; Chapman G; Meletis K; Muhr J; Lendahl U
Article: BMC NEUROSCIENCE. 2005;6:28
Transcriptome analysis in primary neural stem cells using a tag cDNA amplification method -: art. no. 28
Sievertzon M; Wirta V; Mercer A; Meletis K; Erlandsson R; Wikström L; Frisén J; Lundeberg J
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Anställningar

Professor, Neurovetenskap, Karolinska Institutet, 2021-

Examina och utbildning

Docent, Neurovetenskap, Karolinska Institutet, 2015
MEDICINE DOKTORSEXAMEN, Institutionen för cell- och molekylärbiologi, Karolinska Institutet, 2006
Medicine Magisterexamen, Karolinska Institutet, 2000

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