Charlotte Rolny

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: CELL REPORTS. 2023;42(12):113507

Report VEGF-C-expressing TAMs rewire the metastatic fate of breast cancer cells

Banerjee K; Kerzel T; Bekkhus T; Ferreira SDS; Wallmann T; Wallerius M; Landwehr L-S; Agardy DA; Schauer N; Malmerfeldt A; Bergh J; Bartish M; Hartman J; Ostman A; Squadrito ML; Rolny C
Article: JOURNAL FOR IMMUNOTHERAPY OF CANCER. 2022;10(10):e005308

Tumor MHC class I expression alters cancer-associated myelopoiesis driven by host NK cells

Neo SY; Jing X; Tong L; Tong D; Gao J; Chen Z; De Los Santos MC; Burduli N; Ferreira SDS; Wagner AK; Alici E; Rolny C; Cao Y; Lundqvist A
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(10):e2017089118

TAp73 represses NF-κB-mediated recruitment of tumor-associated macrophages in breast cancer

Wolfsberger J; Sakil HAM; Zhou L; van Bree N; Baldisseri E; Ferreira SDS; Zubillaga V; Stantic M; Fritz N; Hartman J; Rolny C; Wilhelm MT
Article: GYNECOLOGIC ONCOLOGY. 2020;159(3):860-868

High density of stroma-localized CD11c-positive macrophages is associated with longer overall survival in high-grade serous ovarian cancer

Corvigno S; Mezheyeuski A; De La Fuente LM; Westbom-Freme S; Carlson JW; Fernebro J; Avall-Lundqvist E; Kannisto P; Hedenfalk I; Malander S; Rolny C; Dahlstrand H; Ostman A
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2020;117(44):27556-27565

MNK2 governs the macrophage antiinflammatory phenotype

Bartish M; Tong D; Pan Y; Wallerius M; Liu H; Ristau J; Ferreira SDS; Wallmann T; van Hoef V; Masvidal L; Kerzel T; Joly A-L; Goncalves C; Preston SEJ; Ebrahimian T; Seitz C; Bergh J; Pietras K; Lehoux S; Naldini L; Andersson J; Squadrito ML; del RSV; Larsson O; Rolny C
Article: CANCERS. 2019;11(10):E1479-1479

STAT3 Activity Promotes Programmed-Death Ligand 1 Expression and Suppresses Immune Responses in Breast Cancer

Zerdes I; Wallerius M; Sifakis EG; Wallmann T; Betts S; Bartish M; Tsesmetzis N; Tobin NP; Coucoravas C; Bergh J; Rassidakis GZ; Rolny C; Foukakis T
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2019;200(3):348-358

Distinct Cancer-Promoting Stromal Gene Expression Depending on Lung Function

Sandri BJ; Masvidal L; Murie C; Bartish M; Avdulov S; Higgins L; Markowski T; Peterson M; Bergh J; Yang P; Rolny C; Limper AH; Griffin TJ; Bitterman PB; Wendt CH; Larsson O
Article: CLINICAL CANCER RESEARCH. 2019;25(12):3702-3717

A Novel ACKR2-Dependent Role of Fibroblast-Derived CXCL14 in Epithelial-to-Mesenchymal Transition and Metastasis of Breast Cancer

Sjoberg E; Meyrath M; Milde L; Herrera M; Lovrot J; Hagerstrand D; Frings O; Bartish M; Rolny C; Sonnhammer E; Andy CE; Augsten M; Ostman A
Journal article: PANCREATOLOGY. 2019;19:s28-s29

Smad7 is required for normal macrophage function in experimental chronic pancreatitis

Li X; Wallmann T; Nania S; Hornung L; Kleiter I; Löhr J-M; Rolny C; Heuchel R
Journal article: ANNALS OF THE AMERICAN THORACIC SOCIETY. 2018;15(Supplement_4):s290-s291

Chronic Obstructive Pulmonary Disease Phenotype Dictates Cancer-Promoting Stromal Gene Expression Programs

Wendt CH; Sandri BJ; Masvidal L; Murie C; Bartish M; Avdulov S; Higgins L; Markowski T; Peterson M; Bergh J; Yang P; Rolny C; Limper AH; Griffin TJ; Bitterman PB; Larsson O
Article: ISCIENCE. 2018;9:71-83

Microglia Induce PDGFRB Expression in Glioma Cells to Enhance Their Migratory Capacity

Wallmann T; Zhang X-M; Wallerius M; Bolin S; Joly A-L; Sobocki C; Leiss L; Jiang Y; Bergh J; Holland EC; Enger PO; Andersson J; Swartling FJ; Miletic H; Uhrbom L; Harris RA; Rolny C
Article: CANCER IMMUNOLOGY RESEARCH. 2018;6(11):1417-1425

Cripto-1 Plasmid DNA Vaccination Targets Metastasis and Cancer Stem Cells in Murine Mammary Carcinoma

Witt K; Ligtenberg MA; Conti L; Lanzardo S; Ruiu R; Wallmann T; Tufvesson-Stiller H; Chambers BJ; Rolny C; Lladser A; Lundqvist A; Cavallo F; Kiessling R
Article: ONCOIMMUNOLOGY. 2017;6(8):e1338238

Zoledronic acid inhibits NFAT and IL-2 signaling pathways in regulatory T cells and diminishes their suppressive function in patients with metastatic cancer

Sarhan D; Leijonhufvud C; Murray S; Witt K; Seitz C; Wallerius M; Xie H; Ullen A; Harmenberg U; Lidbrink E; Rolny C; Andersson J; Lundqvist A
Article: CANCER RESEARCH. 2016;76(11):3166-3178

Guidance Molecule SEMA3A Restricts Tumor Growth by Differentially Regulating the Proliferation of Tumor-Associated Macrophages

Wallerius M; Wallmann T; Bartish M; Ostling J; Mezheyeuski A; Tobin NP; Nygren E; Pangigadde P; Pellegrini P; Squadrito ML; Ponten F; Hartman J; Bergh J; DeMilito A; De Palma M; Ostman A; Andersson J; Rolny C
Article: CELL REPORTS. 2016;15(9):2000-2011

Reprogramming Tumor-Associated Macrophages by Antibody Targeting Inhibits Cancer Progression and Metastasis

Georgoudaki A-M; Prokopec KE; Boura VF; Hellqvist E; Sohn S; Ostling J; Dahan R; Harris RA; Rantalainen M; Klevebring D; Sund M; Brage SE; Fuxe J; Rolny C; Li F; Ravetch JV; Karlsson MCI
Article: SCIENCE. 2015;347(6226):1138-1142

Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq

Zeisel A; Munoz-Manchado AB; Codeluppi S; Lonnerberg P; La Manno G; Jureus A; Marques S; Munguba H; He L; Betsholtz C; Rolny C; Castelo-Branco G; Hjerling-Leffler J; Linnarsson S
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2013;43(1):249-257

Activated monocytes augment TRAIL-mediated cytotoxicity by human NK cells through release of IFN-γ

Sarhan D; D'Arcy P; Wennerberg E; Liden M; Hu J; Winqvist O; Rolny C; Lundqvist A
Article: CANCER RESEARCH. 2012;72(8):1953-1963

Genetic Deficiency in Plasma Protein HRG Enhances Tumor Growth and Metastasis by Exacerbating Immune Escape and Vessel Abnormalization

Tugues S; Honjo S; Konig C; Noguer O; Hedlund M; Botling J; Deschoemaeker S; Wenes M; Rolny C; Jahnen-Dechent W; Mazzone M; Claesson-Welsh L
Journal article: JOURNAL OF CLINICAL INVESTIGATION. 2011;121(7):2945

Sema3E–Plexin D1 signaling drives human cancer cell invasiveness and metastatic spreading in mice

Casazza A; Finisguerra V; Capparuccia L; Camperi A; Swiercz JM; Rizzolio S; Rolny C; Christensen C; Bertotti A; Sarotto I; Risio M; Trusolino L; Weitz J; Schneider M; Mazzone M; Comoglio PM; Tamagnone L
Journal article: CANCER RESEARCH. 2011;71(8_Supplement):3268

Abstract 3268: Targeting Semaphorin signaling to inhibit tumor growth and metastatic spreading

Casazza A; Kigel B; Rolny C; Neufeld G; Tamagnone L
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2011;31(4):741-749

Systemic and Targeted Delivery of Semaphorin 3A Inhibits Tumor Angiogenesis and Progression in Mouse Tumor Models

Casazza A; Fu X; Johansson I; Capparuccia L; Andersson F; Giustacchini A; Squadrito ML; Venneri MA; Mazzone M; Larsson E; Carmeliet P; De Palma M; Naldini L; Tamagnone L; Rolny C
Article: CANCER CELL. 2011;19(1):31-44

HRG Inhibits Tumor Growth and Metastasis by Inducing Macrophage Polarization and Vessel Normalization through Downregulation of PIGF

Rolny C; Mazzone M; Tugues S; Laoui D; Johansson I; Coulon C; Squadrito ML; Segura I; Li X; Knevels E; Costa S; Vinckier S; Dresselaer T; Akerud P; De Mol M; Salomaki H; Phillipson M; Wyns S; Larsson E; Buysschaert I; Botling J; Himmelreich U; Van Ginderachter JA; De Palma M; Dewerchin M; Claesson-Welsh L; Carmeliet P
Article: DIABETES. 2010;59(10):2569-2578

Clinical and Experimental Pancreatic Islet Transplantation to Striated Muscle Establishment of a Vascular System Similar to That in Native Islets

Christoffersson G; Henriksnas J; Johansson L; Rolny C; Ahlstrom H; Caballero-Corbalan J; Segersvard R; Permert J; Korsgren O; Carlsson P-O; Phillipson M
Article: BLOOD. 2010;116(11):1924-1931

A chemotactic gradient sequestered on endothelial heparan sulfate induces directional intraluminal crawling of neutrophils

Massena S; Christoffersson G; Hjertstrom E; Zcharia E; Vlodavsky I; Ausmees N; Rolny C; Li J-P; Phillipson M
Article: JOURNAL OF CLINICAL INVESTIGATION. 2010;120(8):2684-2698

Sema3E-Plexin D1 signaling drives human cancer cell invasiveness and metastatic spreading in mice

Casazza A; Finisguerra V; Capparuccia L; Camperi A; Swiercz JM; Rizzolio S; Rolny C; Christensen C; Bertotti A; Sarotto I; Risio M; Trusolino L; Weitz J; Schneider M; Mazzone M; Comoglio PM; Tamagnone L
Article: CELL. 2010;141(1):178-190

Further Pharmacological and Genetic Evidence for the Efficacy of PlGF Inhibition in Cancer and Eye Disease

Van de Veire S; Stalmans I; Heindryckx F; Oura H; Tijeras-Raballand A; Schmidt T; Loges S; Albrecht I; Jonckx B; Vinckier S; Van Steenkiste C; Tugues S; Rolny C; De Mol M; Dettori D; Hainaud P; Coenegrachts L; Contreres J-O; Van Bergen T; Cuervo H; Xiao W-H; Le Henaff C; Buysschaert I; Masouleh BK; Geerts A; Schomber T; Bonnin P; Lambert V; Haustraete J; Zacchigna S; Rakic J-M; Jimenez W; Noel A; Giacca M; Colle I; Foidart J-M; Tobelem G; Morales-Ruiz M; Vilar J; Maxwell P; Vinores SA; Carmeliet G; Dewerchin M; Claesson-Welsh L; Dupuy E; Van Vlierberghe H; Christofori G; Mazzone M; Detmar M; Collen D; Carmeliet P
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2008;205(5):1155-1171

The tumor suppressor semaphorin 3B triggers a prometastatic program mediated by interleukin 8 and the tumor microenvironment

Rolny C; Capparuccia L; Casazza A; Mazzone M; Vallario A; Cignetti A; Medico E; Carmeliet P; Comoglio PM; Tamagnone L
Article: BLOOD. 2006;108(6):1877-1886

Platelet-derived growth factor receptor-β promotes early endothelial cell differentiation

Rolny C; Nilsson I; Magnusson P; Armulik A; Jakobsson L; Wentzel P; Lindblom P; Norlin J; Betsholtz C; Heuchel R; Welsh M; Claesson-Welsh L
Article: EXPERIMENTAL CELL RESEARCH. 2005;308(2):381-393

Shb promotes blood vessel formation in embryoid bodies by augmenting vascular endothelial growth factor receptor-2 and platelet-derived growth factor receptor-β signaling

Rolny C; Lu LG; Ågren N; Nilsson I; Roe C; Webb GC; Welsh M
Article: FASEB JOURNAL. 2004;18(13):1507-1515

Vascular endothelial growth factor receptor-3 in hypoxia-induced vascular development

Nilsson I; Rolny C; Wu Y; Pytowski B; Hicklin D; Alitalo K; Claesson-Welsh L; Wennström S
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2004;279(21):22267-22275

The adaptor protein shb binds to tyrosine 1175 in vascular endothelial growth factor (VEGF) receptor-2 and regulates VEGF-dependent cellular migration

Holmqvist K; Cross MJ; Rolny C; Hägerkvist R; Rahimi N; Matsumoto T; Claesson-Welsh L; Welsh M
Article: JOURNAL OF CELL SCIENCE. 2004;117(8):1513-1523

Deregulation of Flk-1/vascular endothelial growth factor receptor-2 in fibroblast growth factor receptor-1-deficient vascular stem cell development

Magnusson P; Rolny C; Jakobsson L; Wikner C; Wu Y; Hicklin DJ; Claesson-Welsh L
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2002;277(22):19315-19321

Heparin amplifies platelet-derived growth factor (PDGF)-BB-induced PDGF α-receptor but not PDGF β-receptor tyrosine phosphorylation in heparan sulfate-deficient cells -: Effects on signal transduction and biological responses

Rolny C; Spillmann D; Lindahl U; Claesson-Welsh L
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 1998;12(2):309-313

Expression of human endogenous retrovirus ERV3 (HERV-R) mRNA in normal and neoplastic tissues

Andersson AC; Svensson AC; Rolny C; Andersson G; Larsson E
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Review: NATURE REVIEWS CANCER. 2023;23(6):408-425

The role of eIF4F-driven mRNA translation in regulating the tumour microenvironment

Bartish M; Abraham MJ; Goncalves C; Larsson O; Rolny C; Del Rincon SV
Meeting abstract: CANCER RESEARCH. 2023;83(5_Supplement):p2-20-08-p2-20-08

Abstract P2-20-08: Expression of ACVRL1 in a subset of recruited tumor-associated macrophages drives resistance to PD-1 therapy in human breast cancer

Talkhoncheh MS; Sjölund J; Balbas PB; Kurzejamska E; Larsson S; Cordero E; Oudenaarden CR; Pantaleo J; Jonsson G; Rolny C; Bocci M; Pietras K
Preprint: BIORXIV. 2022

VEGF-C expression in TAMs rewires the metastatic fate of breast cancer cells

Banerjee K; Kerzel T; Bekkhus T; de Souza Ferreira S; Wallmann T; Wallerius M; Landwehr L-S; Agardy DA; Schauer N; Malmerfeldt A; Bergh J; Bartish M; Hartman J; Östman A; Squadrito ML; Rolny C
Corrigendum: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(46):e2117333118

TAp73 represses NF-κB-mediated recruitment of tumor-associated macrophages in breast cancer (vol 118, e2017089118, 2021)

Wolfsberger J; Sakil HAM; Zhou L; van Bree N; Baldisseri E; Ferreira SDS; Zubillaga V; Stantic M; Fritz N; Hartman J; Rolny C; Wilhelm MT
Meeting abstract: CANCER IMMUNOLOGY RESEARCH. 2018;6(9):a77

Cripto-1 vaccination elicits protective immune response to metastatic breast cancer and breast cancer stem cells

Witt K; Ligtenberg MA; Conti L; Lanzardo S; Ruiu R; Tufvesson-Stiller H; Ostling J; Rolny C; Lladser A; Lundqvist A; Cavallo F; Kiessling R
Meeting abstract: JOURNAL OF CLINICAL ONCOLOGY. 2017;35:e23088

Regulation of PD-L1 in breast cancer

Zerdes I; Tsesmetzis N; Lovrot J; Rolny C; Bergh JCS; Rassidakis G; Foukakis T
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):312-313

Differential translational regulation dictates the TAM phenotype during the course of tumor growth

Bartish M; Wallerius M; Wallmann T; Sanz LM; van Hoef V; Joly A-L; Andersson J; Larsson O; Rolny C
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):315

Polysomal profiling reveals differential translational regulation in TAMs during tumor growth

Bartish M; Wallerius M; Wallmann T; Sanz LM; Van Hoef V; Joly A-L; Andersson J; Rolny C; Larsson O
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):314-315

Semaphorin3A re-educates myeloid derived suppressor cells toward a pro-inflammatory phenotype

Wallerius M; Bartish M; Wallmann T; Andresson J; Rolny C
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):315-316

Macrophage-derived Vascular Endothelial Growth Factor C re-directs hematogenous metastatic dissemination by normalizing the tumor vasculature

Wallmann T; Wallerius M; Landwehr L; Agardy D; Bartish M; Squadrito M; De Palma M; Rolny C
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):334

Cripto-1 vaccination elicits protective immune response to metastatic breast cancer and breast CSC

Witt K; Ligtenberg MA; Conti L; Lanzardo S; Tufvesson-Stiller H; Ostling J; Rolny C; Lladser A; Lundqvist A; Cavallo F; Kiessling R
Corrigendum: JOURNAL OF CLINICAL INVESTIGATION. 2013;123(12):5411

Sema3E-Plexin D1 signaling drives human cancer cell invasiveness and metastatic spreading in mice (vol 120, pg 2684, 2010)

Casazza A; Finisguerra V; Capparuccia L; Camperi A; Swiercz JM; Rizzolio S; Rolny C; Christensen C; Bertotti A; Sarotto I; Risio M; Trusolino L; Weitz J; Schneider M; Mazzone M; Comoglio PM; Tamagnone L
Review: EXPERIMENTAL CELL RESEARCH. 2013;319(11):1635-1643

The role of immune semaphorins in cancer progression

Eissler N; Rolny C
Conference publication: DIABETOLOGIA. 2010;53:S60

Clinical and experimental pancreatic islet transplantation to striated muscle: Establishment of a vascular system similar to that in native islets

Christoffersson G; Henriksnas J; Johansson L; Rolny C; Ahlstrom H; Caballero-Corbalan J; Segersvard R; Permert J; Korsgren O; Carlsson P-O; Phillipson M
Book chapter: HANDBOOK OF CELL SIGNALING. 2010;p. 1927-1937

Chapter 236 Vascular Endothelial Growth Factors and Receptors Signaling in Vascular Development

Dimberg A; Rolny C; van Meeteren LA; Claesson-Welsh L

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