Boel Brynedal

Publikationer
Forskningsbidrag
CV
Populärvetenskap och samverkan

Artiklar

Article: CARDIOVASCULAR DIABETOLOGY. 2025;24(1):244
Characterizing trajectories of diabetes-related health parameters before diabetes diagnosis in diabetes subtypes: analysis of a 20-year long prospective cohort study in Sweden
Liedtke TP; Strathmann EA; Ahlqvist E; Asplund O; Penz CS; Stuermer P; Oevermoehle C; Lager A; Brynedal B; Gudjonsdottir H; Lieb W; Weber KS
Article: BMC PRIMARY CARE. 2025;26(1):20
Differences between private and public primary health care centers and differences between men and women in antihypertensive care and cardiovascular prevention in all patients with hypertension treated in primary care in Stockholm County, Sweden
Wandell P; Norrman A; Eriksson J; Ivarsson C; Gudjonsdottir H; Hagstromer M; Lundh L; Hasselstrom J; Brynedal B; Sandlund C; Carlsson AC
Article: EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY. 2025;:zwaf013
Risk stratification for cardiovascular disease: a comparative analysis of cluster analysis and traditional prediction models
Mendez DY; Zhou M; Brynedal B; Gudjonsdottir H; Tynelius P; Lagerros YT; Lager A
Article: PREVENTIVE MEDICINE REPORTS. 2024;44:102806
Predicting new cases of hypertension in Swedish primary care with a machine learning tool
Norrman A; Hasselstrom J; Ljunggren G; Wachtler C; Eriksson J; Kahan T; Wandell P; Gudjonsdottir H; Lindblom S; Ruge T; Rosenblad A; Brynedal B; Carlsson AC
Journal article: PREVENTIVE MEDICINE REPORTS. 2024;44:102806
Predicting new cases of hypertension in Swedish primary care with a machine learning tool.
Norrman A; Hasselström J; Ljunggren G; Wachtler C; Eriksson J; Kahan T; Wändell P; Gudjonsdottir H; Lindblom S; Ruge T; Rosenblad A; Brynedal B; Carlsson AC
Article: AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. 2024;231(1):107.e1-107.e19
Mode of delivery and subsequent self-perceived sexual life satisfaction: a population-based cohort study
Zweygberg AL; Martin FZ; Brynedal B; Lindholm ES; Kosidou K; Ahlqvist VH; Magnusson C
Article: NEURO-ONCOLOGY PRACTICE. 2024;11(6):723-732
Health-related quality of life in surgically treated asymptomatic meningioma patients: A population-based matched cohort study
Naslund O; Jakobsson S; Thurin E; Skoglund T; Pettersson-Segerlind J; Brynedal B; Jakola AS; Bartek Jr J
Article: PREVENTIVE MEDICINE. 2024;183:107969
The influence of the COVID-19 pandemic on physical activity in Stockholm County - Evidence from time series models of smartphone measured daily steps data spanning over 3 years
Zhou M; Gebreslassie M; Leon APD; Tynelius P; Ahlqvist VH; Dahlen M; Berglind D; Lager A; Brynedal B
Article: BMC MEDICINE. 2024;22(1):168
Undiagnosed type 2 diabetes is common - intensified screening of established risk groups is imperative in Sweden: the SDPP cohort
Gudjonsdottir H; Tynelius P; Stattin NS; Mendez DY; Lager A; Brynedal B
Article: ENVIRONMENTAL RESEARCH. 2023;239(Pt 1):117230
Multiple myeloma risk in relation to long-term air pollution exposure - A pooled analysis of four European cohorts
Hvidtfeldt UA; Chen J; Rodopoulou S; Strak M; de Hoogh K; Bellander T; Brandt JO; Forastiere F; Brynedal B; Hertel O; Hoffmann B; Katsouyanni K; Ketzel M; Leander K; Magnusson PKE; Nagel G; Pershagen G; Rizzuto D; Samoli E; So R; Stafoggia M; Onneland AT; Weinmayr G; Wolf K; Zitt E; Brunekreef B; Hoek G; Raaschou-Nielsen O
Article: BJPSYCH OPEN. 2023;9(6):e205
Migration background, eating disorder symptoms and healthcare service utilisation: findings from the Stockholm Public Health Cohort
Strand M; Baarnhielm S; Fredlund P; Brynedal B; Welch E
Article: SCIENTIFIC REPORTS. 2023;13(1):10058
Peripheral blood cellular dynamics of rheumatoid arthritis treatment informs about efficacy of response to disease modifying drugs
Hedman AK; Winter E; Yoosuf N; Benita Y; Berg L; Brynedal B; Folkersen L; Klareskog L; Maciejewski M; Sirota-Madi A; Spector Y; Ziemek D; Padyukov L; Shen-Orr SS; Jelinsky SA
Article: FRONTIERS IN MEDICINE. 2023;10:1146353
Molecular signature of methotrexate response among rheumatoid arthritis patients
Brynedal B; Yoosuf N; Ulfarsdottir TB; Ziemek D; Maciejewski M; Folkersen L; Westerlind H; Mueller M; Sahlstrom P; Jelinsky SA; Hensvold A; Padyukov L; Pomiano NV; Catrina A; Klareskog L; Berg L
Article: CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION. 2023;32(1):105-113
Breast Cancer Incidence in Relation to Long-Term Low-Level Exposure to Air Pollution in the ELAPSE Pooled Cohort
Hvidtfeldt UA; Chen J; Rodopoulou S; Strak M; de Hoogh K; Andersen ZJ; Bellander T; Brandt J; Fecht D; Forastiere F; Gulliver J; Hertel O; Hoffmann BH; Katsouyanni K; Ketzel M; Brynedal B; Leander K; Ljungman PLS; Magnusson PKE; Nagel G; Pershagen G; Rizzuto D; Boutron-Ruault M-C; Samoli E; So R; Stafoggia M; Tjonneland A; Vermeulen R; Verschuren WMM; Weinmayr G; Wolf K; Zhang J; Zitt E; Brunekreef B; Hoek G; Raaschou-Nielsen O
Article: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 2022;51(6):e401-e413
Cohort Profile: The Stockholm Diabetes Prevention Programme (SDPP)
Gudjonsdottir H; Tynelius P; Fors S; Mendez DY; Gebreslassie M; Zhou M; Carlsson AC; Svefors P; Wandell P; Ostenson C-G; Brynedal B; Lager A
Article: BMC MEDICINE. 2022;20(1):356
Characterization of data-driven clusters in diabetes-free adults and their utility for risk stratification of type 2 diabetes
Mendez DY; Zhou M; Lagerros YT; Velasco DVG; Tynelius P; Gudjonsdottir H; de Leon AP; Eeg-Olofsson K; Ostenson C-G; Brynedal B; Aguilar Salinas CA; Ebbevi D; Lager A
Article: ENVIRONMENT INTERNATIONAL. 2022;166:107341
Exposure to surrounding greenness and natural-cause and cause-specific mortality in the ELAPSE pooled cohort
Bereziartua A; Chen J; de Hoogh K; Rodopoulou S; Andersen ZJ; Bellander T; Brandt J; Fecht D; Forastiere F; Gulliver J; Hertel O; Hoffmann B; Hvidtfeldt UA; Verschuren WMM; Joeckel K-H; Jorgensen JT; Katsouyanni K; Ketzel M; Krog NH; Brynedal B; Leander K; Liu S; Ljungman P; Faure E; Magnusson PKE; Nagel G; Pershagen G; Peters A; Raaschou-Nielsen O; Renzi M; Rizzuto D; Samoli E; van der Schouw YT; Schramm S; Severi G; Stafoggia M; Strak M; Sorensen M; Tjonneland A; Weinmayr G; Wolf K; Zitt E; Brunekreef B; Hoek G
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:804822
Antibodies to a Citrullinated Porphyromonas gingivalis Epitope Are Increased in Early Rheumatoid Arthritis, and Can Be Produced by Gingival Tissue B Cells: Implications for a Bacterial Origin in RA Etiology
Sherina N; de Vries C; Kharlamova N; Sippl N; Jiang X; Brynedal B; Kindstedt E; Hansson M; Mathsson-Alm L; Israelsson L; Stalesen R; Saevarsdottir S; Holmdahl R; Hensvold A; Johannsen G; Eriksson K; Sallusto F; Catrina AI; Roennelid J; Groenwall C; Yucel-Lindberg T; Alfredsson L; Klareskog L; Piccoli L; Malmstroem V; Amara K; Lundberg K
Article: RHEUMATOLOGY. 2022;61(4):1680-1689
Early prediction of clinical response to anti-TNF treatment using multi-omics and machine learning in rheumatoid arthritis
Yoosuf N; Maciejewski M; Ziemek D; Jelinsky SA; Folkersen L; Muller M; Sahlstrom P; Vivar N; Catrina A; Berg L; Klareskog L; Padyukov L; Brynedal B
Article: MULTIPLE SCLEROSIS JOURNAL. 2021;27(7):1014-1026
Methylome and transcriptome signature of bronchoalveolar cells from multiple sclerosis patients in relation to smoking
Ringh MV; Hagemann-Jensen M; Needhamsen M; Kullberg S; Wahlstrom J; Grunewald J; Brynedal B; Jagodic M; Ekstrom TJ; Ockinger J; Kular L
Article: PLOS ONE. 2021;16(4):e0250282
Understanding interactions between risk factors, and assessing the utility of the additive and multiplicative models through simulations
Diaz-Gallo L-M; Brynedal B; Westerlind H; Sandberg R; Ramskold D
Article: ARTHRITIS RESEARCH & THERAPY. 2020;22(1):170
Presence of autoantibodies in "seronegative" rheumatoid arthritis associates with classical risk factors and high disease activity
Reed E; Hedstrom AK; Hansson M; Mathsson-Alm L; Brynedal B; Saevarsdottir S; Cornillet M; Jakobsson P-J; Holmdahl R; Skriner K; Serre G; Alfredsson L; Ronnelid J; Lundberg K
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2019;105(3):616-624
Distinct HLA Associations with Rheumatoid Arthritis Subsets Defined by Serological Subphenotype
Terao C; Brynedal B; Chen Z; Jiang X; Westerlind H; Hansson M; Jakobsson P-J; Lundberg K; Skriner K; Serre G; Ronnelid J; Mathsson-Alm L; Brink M; Dahlqvist SR; Padyukov L; Gregersen PK; Barton A; Alfredsson L; Klareskog L; Raychaudhuri S
Article: EBIOMEDICINE. 2019;46:290-304
Tobacco smoking induces changes in true DNA methylation, hydroxymethylation and gene expression in bronchoalveolar lavage cells
Ringh MV; Hagemann-Jensen M; Needhamsen M; Kular L; Breeze CE; Sjoholm LK; Slavec L; Kullberg S; Wahlstrom J; Grunewald J; Brynedal B; Liu Y; Almgren M; Jagodic M; Ockinger J; Ekstrom TJ
Article: ANNALS OF THE RHEUMATIC DISEASES. 2018;77(10):1454-1462
Systematic approach demonstrates enrichment of multiple interactions between non-HLA risk variants and HLA-DRB1 risk alleles in rheumatoid arthritis
Diaz-Gallo L-M; Ramskold D; Shchetynsky K; Folkersen L; Chemin K; Brynedal B; Uebe S; Okada Y; Alfredsson L; Klareskog L; Padyukov L
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2017;100(4):581-591
Large-Scale trans-eQTLs Affect Hundreds of Transcripts and Mediate Patterns of Transcriptional Co-regulation
Brynedal B; Choi J; Raj T; Bjornson R; Stranger BE; Neale BM; Voight BF; Cotsapas C
Article: GUT. 2017;66(3):421-428
Dense genotyping of immune-related loci identifies HLA variants associated with increased risk of collagenous colitis
Westerlind H; Mellander M-R; Bresso F; Munch A; Bonfiglio F; Assadi G; Rafter J; Huebenthal M; Lieb W; Kallberg H; Brynedal B; Padyukov L; Halfvarson J; Torkvist L; Bjork J; Andreasson A; Agreus L; Almer S; Miehlke S; Madisch A; Ohlsson B; Lofberg R; Hultcrantz R; Franke A; D'Amato M
Article: MOLECULAR MEDICINE. 2016;22:322-328
Integration of Known DNA, RNA and Protein Biomarkers Provides Prediction of Anti-TNF Response in Rheumatoid Arthritis: Results from the COMBINE Study
Folkersen L; Brynedal B; Diaz-Gallo LM; Ramskold D; Shchetynsky K; Westerlind H; Sundstrom Y; Schepis D; Hensvold A; Vivar N; Eloranta M-L; Ronnblom L; Brunak S; Malmstrom V; Catrina A; Moerch UGW; Klareskog L; Padyukov L; Berg L
Journal article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75:146
OP0234 Rheumatoid Arthritis Subsets Defined by Sub-Specificities of Anti-Citrullinated Antibodies (ACPAS) Have Unique HLA Associations
Brynedal B; Terao C; Chen Z; Jiang X; Westerlind H; Hansson M; Jakobsson P-J; Skriner K; Serre G; Rönnelid J; Padyukov L; Gregersen P; Worthington J; Alfredsson L; Raychaudhuri S; Klareskog L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2015;74(4):762-768
Genetic risk scores and number of autoantibodies in patients with rheumatoid arthritis
Maehlen MT; Olsen IC; Andreassen BK; Viken MK; Jiang X; Alfredsson L; Kallberg H; Brynedal B; Kurreeman F; Daha N; Toes R; Zhernakova A; Gutierrez-Achury J; de Bakker PIW; Martin J; Teruel M; Gonzalez-Gay MA; Rodriguez-Rodriguez L; Balsa A; Uhlig T; Kvien TK; Lie BA
Journal article: NEUROLOGY. 2014;82(10_supplement)
HLA Genes and Interferon-beta Preparations Influence Risk of Developing Neutralizing Anti-Drug Antibodies in Multiple Sclerosis (P1.213)
Fink K; Link J; Lundkvist M; Hermanrud C; Lima I; Brynedal B; Kockum I; Hillert J; Fogdell-Hahn A
Article: PLOS ONE. 2014;9(3):e90479
Human Leukocyte Antigen Genes and Interferon Beta Preparations Influence Risk of Developing Neutralizing Anti-Drug Antibodies in Multiple Sclerosis
Link J; Ryner ML; Fink K; Hermanrud C; Lima I; Brynedal B; Kockum I; Hillert J; Fogdell-Hahn A
Article: PLOS ONE. 2012;7(5):e36779
Importance of Human Leukocyte Antigen (HLA) Class I and II Alleles on the Risk of Multiple Sclerosis
Link J; Kockum I; Lorentzen AR; Lie BA; Celius EG; Westerlind H; Schaffer M; Alfredsson L; Olsson T; Brynedal B; Harbo HF; Hillert J
Article: JOURNAL OF NEUROIMMUNOLOGY. 2011;237(1-2):98-100
No influence on disease progression of non-HLA susceptibility genes in MS
Lundstrom W; Greiner E; Lundmark F; Westerlind H; Smestad C; Lorentzen AR; Kockum I; Link J; Brynedal B; Celius EG; Harbo HF; Masterman T; Hillert J
Journal article: FUTURE NEUROLOGY. 2011;6(4):511-519
Entering a new phase of multiple sclerosis genetic epidemiology
Brynedal B; Hillert J
Article: JOURNAL OF IMMUNOLOGY. 2011;186(3):1338-1342
Cutting Edge: TIGIT Has T Cell-Intrinsic Inhibitory Functions
Joller N; Hafler JP; Brynedal B; Kassam N; Spoerl S; Levin SD; Sharpe AH; Kuchroo VK
Article: JOURNAL OF NEUROIMMUNOLOGY. 2010;226(1-2):172-176
Two HLA class I genes independently associated with multiple sclerosis
Link J; Lorentzen AR; Kockum I; Duvefelt K; Lie BA; Celius EG; Harbo HF; Hillert J; Brynedal B
Article: GENES AND IMMUNITY. 2010;11(5):397-405
IL12A, MPHOSPH9/CDK2AP1 and RGS1 are novel multiple sclerosis susceptibility loci
Esposito F; Patsopoulos NA; Cepok S; Kockum I; Leppa V; Booth DR; Heard RN; Stewart GJ; Cox M; Scott RJ; Lechner-Scott J; Goris A; Dobosi R; Dubois B; Rioux JD; Oturai AB; Sondergaard HB; Sellebjerg F; Sorensen PS; Reunanen M; Koivisto K; Cournu-Rebeix I; Fontaine B; Winkelmann J; Gieger C; Infante-Duarte C; Zipp F; Bergamaschi L; Leone M; Bergamaschi R; Cavalla P; Lorentzen AR; Mero I-L; Celius EG; Harbo HF; Spurkland A; Comabella M; Brynedal B; Alfredsson L; Bernardinelli L; Robertson NP; Hawkins CP; Barcellos LF; Beecham G; Bush W; Cree BAC; Daly MJ; Ivinson AJ; Aubin C; Compston A; D'Alfonso S; Haines JL; Hauser SL; Hemmer B; Hillert J; McCauley JL; Oksenberg J; Olsson T; Palotie A; Peltonen L; Pericak-Vance MA; Saarela J; Sawcer SJ; Stranger B; Boneschi FM; Comi G; Hafler DA; de Bakker PIW; De Jager PL
Article: JOURNAL OF NEUROIMMUNOLOGY. 2010;220(1-2):120-124
MGAT5 alters the severity of multiple sclerosis
Brynedal B; Wojcik J; Esposito F; Debailleul V; Yaouanq J; Martinelli-Boneschi F; Edan G; Comi G; Hillert J; Abderrahim H
Article: NEUROBIOLOGY OF DISEASE. 2010;37(3):613-621
Gene expression profiling in multiple sclerosis: A disease of the central nervous system, but with relapses triggered in the periphery?
Brynedal B; Khademi M; Wallstrom E; Hillert J; Olsson T; Duvefelt K
Article: RESPIRATORY RESEARCH. 2010;11(1):25
Different HLA-DRB1 allele distributions in distinct clinical subgroups of sarcoidosis patients
Grunewald J; Brynedal B; Darlington P; Nisell M; Cederlund K; Hillert J; Eklund A
Article: JOURNAL OF INTERNAL MEDICINE. 2008;264(5):433-441
A common haplotype of the C-C chemokine receptor 2 gene and HLA-DRB1*0301 are independent genetic risk factors for Lofgren's syndrome
Spagnolo P; Sato H; Grunewald J; Brynedal B; Hillert J; Mana J; Wells AU; Eklund A; Welsh KI; du Bois RM
Article: EUROPEAN JOURNAL OF NEUROLOGY. 2007;14(8):835-840
The impact of HLA-A and-DRB1 on age at onset, disease course and severity in Scandinavian multiple sclerosis patients
Smestad C; Brynedal B; Jonasdottir G; Lorentzen AR; Masterman T; Akesson E; Spurkland A; Lie BA; Palmgren J; Celius EG; Hillert J; Harbo HF
Article: PLOS ONE. 2007;2(7):e664
HLA-A Confers an HLA-DRB1 Independent Influence on the Risk of Multiple Sclerosis
Brynedal B; Duvefelt K; Jonasdottir G; Roos IM; Akesson E; Palmgren J; Hillert J
Article: JOURNAL OF NEUROIMMUNOLOGY. 2005;167(1-2):210-214
Increased levels of APRIL (a proliferation-inducing ligand) mRNA in multiple sclerosis
Thangarajh M; Masterman T; Rot U; Duvefelt K; Brynedal B; Karrenbauer VD; Hillert J
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Alla övriga publikationer

Meeting abstract: JOURNAL OF HYPERTENSION. 2024;42:e2-e3
PREDICTING NEW CASES OF HYPERTENSION IN PRIMARY CARE WITH A MACHINE LEARNING TOOL
Norrman A; Hasselstroem J; Ljunggren G; Wachtler C; Eriksson J; Kahan T; Waendell P; Gudjonsdottir H; Lindblom S; Ruge T; Rosenblad A; Brynedal B; Carlsson AC
Preprint: RESEARCH SQUARE. 2022
Peripheral blood cellular dynamics of Rheumatoid arthritis treatment informs about efficacy of response to disease modifying drugs
Jelinsky S; Hedman Å; Winter E; Yoosuf N; Benita Y; Berg L; Brynedal B; Folkersen L; Klareskog L; Maciejewski M; Sirota-Madi A; Spector Y; Ziemek D; Padyukov L; Shen-Orr S
Preprint: MEDRXIV. 2021
Identification of loci genetically associated with antibodies to specific sets of citrullinated peptides in rheumatoid arthritis patients
Shchetynsky K; Brynedal B; Ramsköld D; Israelsson L; Hansson M; Mathsson-Alm L; Rönnelid J; Rheumatoid Arthritis Consortium International (RAC; Viatte S; Holmdahl R; Catrina A; Alfredsson L; Malmström V; Klareskog L; Gomez-Cabrero D; Padyukov L
Preprint: RESEARCH SQUARE. 2021
Early Prediction of Clinical Response to Anti-TNF Treatment using Multi-omics and Machine Learning in Rheumatoid Arthritis
Yoosuf N; Maciejewski M; Ziemek D; Jelinsky S; Folkersen L; Müller M; Sahlström P; Vivar N; Catrina A; Berg L; Klareskog L; Padyukov L; Brynedal B
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2020;26(3_SUPPL):583
Methylome and transcriptome signature of bronchoalveolar cells from multiple sclerosis patients in relation to smoking
Ringh M; Hagemann-Jensen M; Needhamsen M; Kullberg S; Wahlstrom J; Grunewald J; Brynedal B; Jagodic M; Ekstrom T; Ockinger J; Kular L
Letter: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2020;38(5):1029-1030
Occupational physical workload and development of anti-collagen type II antibodies in rheumatoid arthritis: results from the Swedish EIRA population-based case-control study
Zeng P; Pertsinidou E; Brynedal B; Manivel VA; Klareskog L; Mullazehi M; Saevarsdottir S; Bengtsson C; Alfredsson L; Ronnelid J
Preprint: RESEARCH SQUARE. 2020
Molecular Biomarkers of Anti-TNF Response in Patients with Rheumatoid Arthritis
Yoosuf N; Maciejewski M; Ziemek D; Jelinsky S; Folkersen L; Müller M; Sahlström P; Vivar N; Catrina A; Berg L; Klareskog L; Padyukov L; Brynedal B
Corrigendum: AMERICAN JOURNAL OF HUMAN GENETICS. 2019;105(4):880
Distinct HLA Associations with Rheumatoid Arthritis Subsets Defined by Serological Subphenotype (vol 105, pg 616, 2019)
Terao C; Brynedal B; Chen Z; Jiang X; Westerlind H; Hansson M; Jakobsson P-J; Lundberg K; Skriner K; Serre G; Ronnelid J; Mathsson-Alm L; Brink M; Dahlqvist SR; Padyukov L; Gregersen PK; Barton A; Alfredsson L; Klareskog L; Raychaudhuri S
Preprint: BIORXIV. 2019
Understanding interactions between risk factors, and assessing the utility of the additive and multiplicative models through simulations
Diaz-Gallo L-M; Brynedal B; Westerlind H; Sandberg R; Ramsköld D
Conference publication: ANNALS OF THE RHEUMATIC DISEASES. 2019;78:A13
OCCUPATIONAL PHYSICAL WORKLOAD AND DEVELOPMENT OF ANTI-COLLAGEN TYPE II ANTIBODIES IN RHEUMATOID ARTHRITIS: RESULTS FROM THE SWEDISH EIRA POPULATION-BASED CASE-CONTROL STUDY
Pertsinidou E; Zeng P; Brynedal B; Manivel VA; Klareskog L; Mullazehi M; Saevarsdottir S; Bengtsson C; Alfredsson L; Ronnelid J
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2018;77:A33
CHARACTERISATION OF THE ANTIBODY RESPONSE TO A CITRULLINATED PEPTIDE DERIVED FROM PORPHYROMONAS GINGIVALIS PAD IN RA
Kharlamova N; Brynedal B; Sherina N; Eriksson K; Lindberg T; Hansson M; Israelsson L; Steen J; Malmstrom V; Alfredsson L; Amara K; Lundberg K
Preprint: BIORXIV. 2017
The association between theHLA-DRB1shared epitope alleles and the risk of rheumatoid arthritis is influenced by massive gene-gene interactions
Diaz-Gallo L-M; Ramsköld D; Shchetynsky K; Folkersen L; Chemin K; Brynedal B; Uebe S; Okada Y; Alfredsson L; Klareskog L; Padyukov L
Conference publication: ARTHRITIS & RHEUMATOLOGY. 2016;68
Specific Antibody Subphenotypes in Rheumatoid Arthritis Are Associated with Unique HLA-DRB1 Residues at Position 11
Terao C; Brynedal B; Chen Z; Jiang X; Westerlind H; Hansson M; Mathsson-Alm L; Jakobsson PJ; Skriner K; Serre G; Ronnelid J; Padyukov L; Worthington J; Alfredsson L; Klareskog L; Raychaudhuri S
Conference publication: ARTHRITIS & RHEUMATOLOGY. 2016;68
Antibody Mediated Immunity Drives Response to Methotrexate Treatment in Rheumatoid Arthritis Patients
Brynedal B; Westerlind H; Folkersen L; Padyukov L; Vivar N; Catrina AI; Klareskog L; Berg L
Letter: AMERICAN JOURNAL OF GASTROENTEROLOGY. 2016;111(8):1211-1213
HLA Associations Distinguish Collagenous From Lymphocytic Colitis
Westerlind H; Bonfiglio F; Mellander M-R; Huebenthal M; Brynedal B; Bjork J; Torkvist L; Padyukov L; Ohlsson B; Lofberg R; Hultcrantz R; Franke A; Bresso F; D'Amato M
Preprint: BIORXIV. 2016
Large-scaletrans-eQTLs affect hundreds of transcripts and mediate patterns of transcriptional co-regulation Short:trans-eQTLs reveal patterns of transcriptional co-regulation
Brynedal B; Choi J; Raj T; Bjornson R; Stranger B; Neale B; Voight B; Cotsapas C
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2015;21:435-436
Genetic load in eleven distantly related individuals from an MS high risk area
Imrell K; Masterman T; Brynedal B; Lima I; Hillert J; Kockum I; Landtblom A-M
Conference publication: HLA. 2014;84(1):109
HUMAN LEUKOCYTE ANTIGEN GENES AND INTERFERON BETA PREPARATIONS INFLUENCE RISK OF DEVELOPING NEUTRALIZING ANTI-DRUG ANTIBODIES IN MULTIPLE SCLEROSIS
Link J; Ryner ML; Fink K; Hermanrud C; Lima I; Brynedal B; Kockum I; Hillert J; Fogdell-Hahn A
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2014;79(6):450
Human Leucocyte Antigen Genes and Interferon Beta Preparations Influence Risk of Developing Neutralizing Antidrug Antibodies in Multiple Sclerosis
Ryner ML; Link J; Fink K; Hermanrud C; Lima I; Brynedal B; Kockum I; Hillert J; Fogdell-Hahn A
Preprint: ARXIV. 2014
Cross-phenotype meta-analysis reveals large-scale trans-eQTLs mediating patterns of transcriptional co-regulation
Brynedal B; Raj T; Stranger BE; Bjornson R; Neale BM; Voight BF; Cotsapas C
Conference publication: EUROPEAN JOURNAL OF NEUROLOGY. 2012;19:361
Preparation-specific genetically determined risk of developing neutralizing antibodies towards interferon-beta in patients with multiple sclerosis
Link J; Fink K; Lundkvist M; Brynedal B; Kockum I; Fogdell-Hahn A; Hillert J
Conference publication: IMMUNOLOGY. 2012;137:663
Effect of HLA genotype on the development of neutralizing antibodies to interferon beta in patients with multiple sclerosis
Lundkvist M; Link J; Fink K; Hermanrud C; Brynedal B; Fogdell-Hahn A; Kockum I; Hillert J
Conference publication: JOURNAL OF NEUROLOGY. 2012;259:S149
HLA-DRB1*15 and HLA-A*02 are associated with higher risk of developing neutralising antibodies and clinically relevant titres against interferon-beta in multiple sclerosis
Link J; Lundkvist M; Fink K; Hermanrud C; Brynedal B; Fogdell-Hahn A; Kockum I; Hillert J
Conference publication: NEUROLOGY. 2012;78:p05.121
Investigation of the Effect of Human Leukocyte Antigen on the Development of Neutralizing Antibodies in Interferon-beta Treated Patients with Multiple Sclerosis (*The First Three Authors Contributed Equally to This Work)
Fink K; Lundkvist M; Link J; Kockum I; Hermanrud C; Brynedal B; Hillert J; Fogdell-Hahn A
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2011;17:S114
New evidence implicates IRF5 in the pathogenesis of multiple sclerosis
Bomfim IL; Wang C; Khademi M; Sandling J; Brynedal B; Lorentzen AR; Sondergaard HB; Oturai AB; Celius EG; Alfredsson L; Syvanen A-C; Kockum I; Olsson T; Hillert J
Conference publication: JOURNAL OF NEUROLOGY. 2011;258:196
Investigation of HLA genes in multiple sclerosis in Scandinavia
Link J; Kockum I; Lorentzen A; Lie BA; Celius EG; Schaffer M; Brynedal B; Harbo H; Hillert J
Editorial comment: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009;106(23):E58
Differential expression, and genetic association, of CD58 in Swedish multiple sclerosis patients
Brynedal B; Bomfim IL; Olsson T; Duvefelt K; Hillert J
Doctoral thesis: 2009
On genetics and transcriptomics of multiple sclerosis
Brynedal B
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2008;14:S189-S190
Human leukocyte antigen class I risks in multiple sclerosis: A rather than C
Link J; Lorentzen AR; Kockum I; Duvefelt K; Mero I-L; Celius EG; Harbo HF; Hillert J; Brynedal B
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2008;14:S60
Global expression profiling in multiple sclerosis: a disease of the central nervous system, but with relapses triggered in the periphery?
Brynedal B; Khademi M; Wallstroem E; Hillert J; Olsson TP; Duvefelt K
Conference publication: EUROPEAN JOURNAL OF NEUROLOGY. 2007;14:22
The impact of HLA-A and HLA-DRB1 alleles on age at onset, disease course and severity in Scandinavian multiple sclerosis patients
Smestad C; Brynedal B; Jonasdottir G; Lorentzen AR; Masterman T; Akesson E; Spurkland A; Lie BA; Palmgren J; Celius EG; Hillert J; Harbo HF
Conference publication: HLA. 2006;67(6):456
Genetic variation of HLA-A alters the susceptibility to multiple sclerosis
Brynedal B; Duvefelt K; Jonasdottir G; Roos IM; Akesson E; Hillert J
Report:
Screening för hypertoni vid Region Stockholms vårdcentraler
Gudjonsdottir H; Brynedal B
Report:
Personer med omfattande funktionsnedsättning i Stockholms län. Gruppens storlek, levnadsvillkor och vårdkontakter.
Warolén M; Anders W; Brynedal B
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Forskningsbidrag

Notification of the use of return grants for awarded postdoctoral fellowships in medicine or science and technology
Swedish Research Council
1 December 2012 - 30 November 2013
Characterization of the functional relevance of genetic risk variants for autoimmunity in regulatory T cells.
Swedish Research Council
1 January 2010 - 31 December 2011

Anställningar

Epidemiolog, Epidemiologi och folkhälsa, Centrum för epidemiologi och samhällsmedicin, Region Stockholm, 2019-
Anknuten till Forskning, Global folkhälsa, Karolinska Institutet, 2024-2027

Examina och utbildning

Docent, epidemiologi, Karolinska Institutet, 2022
Medicine Doktorsexamen, Institutionen för klinisk neurovetenskap, Karolinska Institutet, 2009

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