Boel Brynedal

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: PREVENTIVE MEDICINE REPORTS. 2024;44:102806

Predicting new cases of hypertension in Swedish primary care with a machine learning tool

Norrman A; Hasselstrom J; Ljunggren G; Wachtler C; Eriksson J; Kahan T; Wandell P; Gudjonsdottir H; Lindblom S; Ruge T; Rosenblad A; Brynedal B; Carlsson AC
Article: AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. 2024;231(1):107.e1-107.e19

Mode of delivery and subsequent self-perceived sexual life satisfaction: a population-based cohort study

Zweygberg AL; Martin FZ; Brynedal B; Lindholm ES; Kosidou K; Ahlqvist VH; Magnusson C
Article: PREVENTIVE MEDICINE. 2024;183:107969

The influence of the COVID-19 pandemic on physical activity in Stockholm County - Evidence from time series models of smartphone measured daily steps data spanning over 3 years

Zhou M; Gebreslassie M; Leon APD; Tynelius P; Ahlqvist VH; Dahlen M; Berglind D; Lager A; Brynedal B
Article: BMC MEDICINE. 2024;22(1):168

Undiagnosed type 2 diabetes is common - intensified screening of established risk groups is imperative in Sweden: the SDPP cohort

Gudjonsdottir H; Tynelius P; Stattin NS; Mendez DY; Lager A; Brynedal B
Article: ENVIRONMENTAL RESEARCH. 2023;239(Pt 1):117230

Multiple myeloma risk in relation to long-term air pollution exposure - A pooled analysis of four European cohorts

Hvidtfeldt UA; Chen J; Rodopoulou S; Strak M; de Hoogh K; Bellander T; Brandt JO; Forastiere F; Brynedal B; Hertel O; Hoffmann B; Katsouyanni K; Ketzel M; Leander K; Magnusson PKE; Nagel G; Pershagen G; Rizzuto D; Samoli E; So R; Stafoggia M; Onneland AT; Weinmayr G; Wolf K; Zitt E; Brunekreef B; Hoek G; Raaschou-Nielsen O
Article: BJPSYCH OPEN. 2023;9(6):e205

Migration background, eating disorder symptoms and healthcare service utilisation: findings from the Stockholm Public Health Cohort

Strand M; Baarnhielm S; Fredlund P; Brynedal B; Welch E
Article: SCIENTIFIC REPORTS. 2023;13(1):10058

Peripheral blood cellular dynamics of rheumatoid arthritis treatment informs about efficacy of response to disease modifying drugs

Hedman AK; Winter E; Yoosuf N; Benita Y; Berg L; Brynedal B; Folkersen L; Klareskog L; Maciejewski M; Sirota-Madi A; Spector Y; Ziemek D; Padyukov L; Shen-Orr SS; Jelinsky SA
Article: CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION. 2023;32(1):105-113

Breast Cancer Incidence in Relation to Long-Term Low-Level Exposure to Air Pollution in the ELAPSE Pooled Cohort

Hvidtfeldt UA; Chen J; Rodopoulou S; Strak M; de Hoogh K; Andersen ZJ; Bellander T; Brandt J; Fecht D; Forastiere F; Gulliver J; Hertel O; Hoffmann BH; Katsouyanni K; Ketzel M; Brynedal B; Leander K; Ljungman PLS; Magnusson PKE; Nagel G; Pershagen G; Rizzuto D; Boutron-Ruault M-C; Samoli E; So R; Stafoggia M; Tjonneland A; Vermeulen R; Verschuren WMM; Weinmayr G; Wolf K; Zhang J; Zitt E; Brunekreef B; Hoek G; Raaschou-Nielsen O
Article: FRONTIERS IN MEDICINE. 2023;10:1146353

Molecular signature of methotrexate response among rheumatoid arthritis patients

Brynedal B; Yoosuf N; Ulfarsdottir TB; Ziemek D; Maciejewski M; Folkersen L; Westerlind H; Mueller M; Sahlstrom P; Jelinsky SA; Hensvold A; Padyukov L; Pomiano NV; Catrina A; Klareskog L; Berg L
Article: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 2022;51(6):E401-E413

Cohort Profile: The Stockholm Diabetes Prevention Programme (SDPP)

Gudjonsdottir H; Tynelius P; Fors S; Mendez DY; Gebreslassie M; Zhou M; Carlsson AC; Svefors P; Wandell P; Ostenson C-G; Brynedal B; Lager A
Article: BMC MEDICINE. 2022;20(1):356

Characterization of data-driven clusters in diabetes-free adults and their utility for risk stratification of type 2 diabetes

Mendez DY; Zhou M; Lagerros YT; Velasco DVG; Tynelius P; Gudjonsdottir H; de Leon AP; Eeg-Olofsson K; Ostenson C-G; Brynedal B; Aguilar Salinas CA; Ebbevi D; Lager A
Article: ENVIRONMENT INTERNATIONAL. 2022;166:107341

Exposure to surrounding greenness and natural-cause and cause-specific mortality in the ELAPSE pooled cohort

Bereziartua A; Chen J; de Hoogh K; Rodopoulou S; Andersen ZJ; Bellander T; Brandt J; Fecht D; Forastiere F; Gulliver J; Hertel O; Hoffmann B; Hvidtfeldt UA; Verschuren WMM; Joeckel K-H; Jorgensen JT; Katsouyanni K; Ketzel M; Krog NH; Brynedal B; Leander K; Liu S; Ljungman P; Faure E; Magnusson PKE; Nagel G; Pershagen G; Peters A; Raaschou-Nielsen O; Renzi M; Rizzuto D; Samoli E; van der Schouw YT; Schramm S; Severi G; Stafoggia M; Strak M; Sorensen M; Tjonneland A; Weinmayr G; Wolf K; Zitt E; Brunekreef B; Hoek G
Article: RHEUMATOLOGY. 2022;61(4):1680-1689

Early prediction of clinical response to anti-TNF treatment using multi-omics and machine learning in rheumatoid arthritis

Yoosuf N; Maciejewski M; Ziemek D; Jelinsky SA; Folkersen L; Muller M; Sahlstrom P; Vivar N; Catrina A; Berg L; Klareskog L; Padyukov L; Brynedal B
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:804822

Antibodies to a Citrullinated Porphyromonas gingivalis Epitope Are Increased in Early Rheumatoid Arthritis, and Can Be Produced by Gingival Tissue B Cells: Implications for a Bacterial Origin in RA Etiology

Sherina N; de Vries C; Kharlamova N; Sippl N; Jiang X; Brynedal B; Kindstedt E; Hansson M; Mathsson-Alm L; Israelsson L; Stalesen R; Saevarsdottir S; Holmdahl R; Hensvold A; Johannsen G; Eriksson K; Sallusto F; Catrina AI; Roennelid J; Groenwall C; Yucel-Lindberg T; Alfredsson L; Klareskog L; Piccoli L; Malmstroem V; Amara K; Lundberg K
Article: MULTIPLE SCLEROSIS JOURNAL. 2021;27(7):1014-1026

Methylome and transcriptome signature of bronchoalveolar cells from multiple sclerosis patients in relation to smoking

Ringh MV; Hagemann-Jensen M; Needhamsen M; Kullberg S; Wahlstrom J; Grunewald J; Brynedal B; Jagodic M; Ekstrom TJ; Ockinger J; Kular L
Article: PLOS ONE. 2021;16(4):e0250282

Understanding interactions between risk factors, and assessing the utility of the additive and multiplicative models through simulations

Diaz-Gallo L-M; Brynedal B; Westerlind H; Sandberg R; Ramskold D
Article: ARTHRITIS RESEARCH & THERAPY. 2020;22(1):170

Presence of autoantibodies in "seronegative" rheumatoid arthritis associates with classical risk factors and high disease activity

Reed E; Hedstrom AK; Hansson M; Mathsson-Alm L; Brynedal B; Saevarsdottir S; Cornillet M; Jakobsson P-J; Holmdahl R; Skriner K; Serre G; Alfredsson L; Ronnelid J; Lundberg K
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2019;105(3):616-624

Distinct HLA Associations with Rheumatoid Arthritis Subsets Defined by Serological Subphenotype

Terao C; Brynedal B; Chen Z; Jiang X; Westerlind H; Hansson M; Jakobsson P-J; Lundberg K; Skriner K; Serre G; Ronnelid J; Mathsson-Alm L; Brink M; Dahlqvist SR; Padyukov L; Gregersen PK; Barton A; Alfredsson L; Klareskog L; Raychaudhuri S
Article: EBIOMEDICINE. 2019;46:290-304

Tobacco smoking induces changes in true DNA methylation, hydroxymethylation and gene expression in bronchoalveolar lavage cells

Ringh MV; Hagemann-Jensen M; Needhamsen M; Kular L; Breeze CE; Sjoholm LK; Slavec L; Kullberg S; Wahlstrom J; Grunewald J; Brynedal B; Liu Y; Almgren M; Jagodic M; Ockinger J; Ekstrom TJ
Article: ANNALS OF THE RHEUMATIC DISEASES. 2018;77(10):1454-1462

Systematic approach demonstrates enrichment of multiple interactions between non-HLA risk variants and HLA-DRB1 risk alleles in rheumatoid arthritis

Diaz-Gallo L-M; Ramskold D; Shchetynsky K; Folkersen L; Chemin K; Brynedal B; Uebe S; Okada Y; Alfredsson L; Klareskog L; Padyukov L
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2017;100(4):581-591

Large-Scale trans-eQTLs Affect Hundreds of Transcripts and Mediate Patterns of Transcriptional Co-regulation

Brynedal B; Choi J; Raj T; Bjornson R; Stranger BE; Neale BM; Voight BF; Cotsapas C
Article: GUT. 2017;66(3):421-428

Dense genotyping of immune-related loci identifies HLA variants associated with increased risk of collagenous colitis

Westerlind H; Mellander M-R; Bresso F; Munch A; Bonfiglio F; Assadi G; Rafter J; Huebenthal M; Lieb W; Kallberg H; Brynedal B; Padyukov L; Halfvarson J; Torkvist L; Bjork J; Andreasson A; Agreus L; Almer S; Miehlke S; Madisch A; Ohlsson B; Lofberg R; Hultcrantz R; Franke A; D'Amato M
Article: MOLECULAR MEDICINE. 2016;22:322-328

Integration of Known DNA, RNA and Protein Biomarkers Provides Prediction of Anti-TNF Response in Rheumatoid Arthritis: Results from the COMBINE Study

Folkersen L; Brynedal B; Diaz-Gallo LM; Ramskold D; Shchetynsky K; Westerlind H; Sundstrom Y; Schepis D; Hensvold A; Vivar N; Eloranta M-L; Ronnblom L; Brunak S; Malmstrom V; Catrina A; Moerch UGW; Klareskog L; Padyukov L; Berg L
Journal article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(Suppl 2):146

OP0234 Rheumatoid Arthritis Subsets Defined by Sub-Specificities of Anti-Citrullinated Antibodies (ACPAS) Have Unique HLA Associations

Brynedal B; Terao C; Chen Z; Jiang X; Westerlind H; Hansson M; Jakobsson P-J; Skriner K; Serre G; Rönnelid J; Padyukov L; Gregersen P; Worthington J; Alfredsson L; Raychaudhuri S; Klareskog L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2015;74(4):762-768

Genetic risk scores and number of autoantibodies in patients with rheumatoid arthritis

Maehlen MT; Olsen IC; Andreassen BK; Viken MK; Jiang X; Alfredsson L; Kallberg H; Brynedal B; Kurreeman F; Daha N; Toes R; Zhernakova A; Gutierrez-Achury J; de Bakker PIW; Martin J; Teruel M; Gonzalez-Gay MA; Rodriguez-Rodriguez L; Balsa A; Uhlig T; Kvien TK; Lie BA
Journal article: NEUROLOGY. 2014;82(10_supplement)

HLA Genes and Interferon-beta Preparations Influence Risk of Developing Neutralizing Anti-Drug Antibodies in Multiple Sclerosis (P1.213)

Fink K; Link J; Lundkvist M; Hermanrud C; Lima I; Brynedal B; Kockum I; Hillert J; Fogdell-Hahn A
Article: PLOS ONE. 2014;9(3):e90479

Human Leukocyte Antigen Genes and Interferon Beta Preparations Influence Risk of Developing Neutralizing Anti-Drug Antibodies in Multiple Sclerosis

Link J; Ryner ML; Fink K; Hermanrud C; Lima I; Brynedal B; Kockum I; Hillert J; Fogdell-Hahn A
Article: PLOS ONE. 2012;7(5):e36779

Importance of Human Leukocyte Antigen (HLA) Class I and II Alleles on the Risk of Multiple Sclerosis

Link J; Kockum I; Lorentzen AR; Lie BA; Celius EG; Westerlind H; Schaffer M; Alfredsson L; Olsson T; Brynedal B; Harbo HF; Hillert J
Article: JOURNAL OF NEUROIMMUNOLOGY. 2011;237(1-2):98-100

No influence on disease progression of non-HLA susceptibility genes in MS

Lundstrom W; Greiner E; Lundmark F; Westerlind H; Smestad C; Lorentzen AR; Kockum I; Link J; Brynedal B; Celius EG; Harbo HF; Masterman T; Hillert J
Journal article: FUTURE NEUROLOGY. 2011;6(4):511-519

Entering a new phase of multiple sclerosis genetic epidemiology

Brynedal B; Hillert J
Article: JOURNAL OF IMMUNOLOGY. 2011;186(3):1338-1342

Cutting edge: TIGIT has T cell-intrinsic inhibitory functions.

Joller N; Hafler JP; Brynedal B; Kassam N; Spoerl S; Levin SD; Sharpe AH; Kuchroo VK
Article: JOURNAL OF NEUROIMMUNOLOGY. 2010;226(1-2):172-176

Two HLA class I genes independently associated with multiple sclerosis

Link J; Lorentzen AR; Kockum I; Duvefelt K; Lie BA; Celius EG; Harbo HF; Hillert J; Brynedal B
Article: GENES AND IMMUNITY. 2010;11(5):397-405

IL12A, MPHOSPH9/CDK2AP1 and RGS1 are novel multiple sclerosis susceptibility loci

Esposito F; Patsopoulos NA; Cepok S; Kockum I; Leppa V; Booth DR; Heard RN; Stewart GJ; Cox M; Scott RJ; Lechner-Scott J; Goris A; Dobosi R; Dubois B; Rioux JD; Oturai AB; Sondergaard HB; Sellebjerg F; Sorensen PS; Reunanen M; Koivisto K; Cournu-Rebeix I; Fontaine B; Winkelmann J; Gieger C; Infante-Duarte C; Zipp F; Bergamaschi L; Leone M; Bergamaschi R; Cavalla P; Lorentzen AR; Mero I-L; Celius EG; Harbo HF; Spurkland A; Comabella M; Brynedal B; Alfredsson L; Bernardinelli L; Robertson NP; Hawkins CP; Barcellos LF; Beecham G; Bush W; Cree BAC; Daly MJ; Ivinson AJ; Aubin C; Compston A; D'Alfonso S; Haines JL; Hauser SL; Hemmer B; Hillert J; McCauley JL; Oksenberg J; Olsson T; Palotie A; Peltonen L; Pericak-Vance MA; Saarela J; Sawcer SJ; Stranger B; Boneschi FM; Comi G; Hafler DA; de Bakker PIW; De Jager PL
Article: JOURNAL OF NEUROIMMUNOLOGY. 2010;220(1-2):120-124

MGAT5 alters the severity of multiple sclerosis

Brynedal B; Wojcik J; Esposito F; Debailleul V; Yaouanq J; Martinelli-Boneschi F; Edan G; Comi G; Hillert J; Abderrahim H
Article: NEUROBIOLOGY OF DISEASE. 2010;37(3):613-621

Gene expression profiling in multiple sclerosis: A disease of the central nervous system, but with relapses triggered in the periphery?

Brynedal B; Khademi M; Wallstrom E; Hillert J; Olsson T; Duvefelt K
Article: RESPIRATORY RESEARCH. 2010;11(1):25

Different HLA-DRB1 allele distributions in distinct clinical subgroups of sarcoidosis patients

Grunewald J; Brynedal B; Darlington P; Nisell M; Cederlund K; Hillert J; Eklund A
Article: JOURNAL OF INTERNAL MEDICINE. 2008;264(5):433-441

A common haplotype of the C-C chemokine receptor 2 gene and HLA-DRB1*0301 are independent genetic risk factors for Lofgren's syndrome

Spagnolo P; Sato H; Grunewald J; Brynedal B; Hillert J; Mana J; Wells AU; Eklund A; Welsh KI; du Bois RM
Article: EUROPEAN JOURNAL OF NEUROLOGY. 2007;14(8):835-840

The impact of HLA-A and-DRB1 on age at onset, disease course and severity in Scandinavian multiple sclerosis patients

Smestad C; Brynedal B; Jonasdottir G; Lorentzen AR; Masterman T; Akesson E; Spurkland A; Lie BA; Palmgren J; Celius EG; Hillert J; Harbo HF
Article: PLOS ONE. 2007;2(7):e664

HLA-A Confers an HLA-DRB1 Independent Influence on the Risk of Multiple Sclerosis

Brynedal B; Duvefelt K; Jonasdottir G; Roos IM; Akesson E; Palmgren J; Hillert J
Article: JOURNAL OF NEUROIMMUNOLOGY. 2005;167(1-2):210-214

Increased levels of APRIL (a proliferation-inducing ligand) mRNA in multiple sclerosis

Thangarajh M; Masterman T; Rot U; Duvefelt K; Brynedal B; Karrenbauer VD; Hillert J
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Alla övriga publikationer

Preprint: RESEARCH SQUARE. 2022

Peripheral blood cellular dynamics of Rheumatoid arthritis treatment informs about efficacy of response to disease modifying drugs

Jelinsky SA; Hedman ÅK; Winter E; Yoosuf N; Benita Y; Berg L; Brynedal B; Folkersen L; Klareskog L; Maciejewski M; Sirota-Madi A; Spector Y; Ziemek D; Padyukov L; Shen-Orr SS
Preprint: MEDRXIV. 2021

Identification of loci genetically associated with antibodies to specific sets of citrullinated peptides in rheumatoid arthritis patients

Shchetynsky K; Brynedal B; Ramsköld D; Israelsson L; Hansson M; Mathsson-Alm L; Rönnelid J; Rheumatoid Arthritis Consortium International (RAC; Viatte S; Holmdahl R; Catrina A; Alfredsson L; Malmström V; Klareskog L; Gomez-Cabrero D; Padyukov L
Preprint: RESEARCH SQUARE. 2021

Early Prediction of Clinical Response to Anti-TNF Treatment using Multi-omics and Machine Learning in Rheumatoid Arthritis

Yoosuf N; Maciejewski M; Ziemek D; Jelinsky SA; Folkersen L; Müller M; Sahlström P; Vivar N; Catrina A; Berg L; Klareskog L; Padyukov L; Brynedal B
Letter: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2020;38(5):1029-1030

Occupational physical workload and development of anti-collagen type II antibodies in rheumatoid arthritis: results from the Swedish EIRA population-based case-control study

Zeng P; Pertsinidou E; Brynedal B; Manivel VA; Klareskog L; Mullazehi M; Saevarsdottir S; Bengtsson C; Alfredsson L; Ronnelid J
Preprint: RESEARCH SQUARE. 2020

Molecular Biomarkers of Anti-TNF Response in Patients with Rheumatoid Arthritis

Yoosuf N; Maciejewski M; Ziemek D; Jelinsky S; Folkersen L; Müller M; Sahlström P; Vivar N; Catrina A; Berg L; Klareskog L; Padyukov L; Brynedal B
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2020;26(3_SUPPL):583

Methylome and transcriptome signature of bronchoalveolar cells from multiple sclerosis patients in relation to smoking

Ringh M; Hagemann-Jensen M; Needhamsen M; Kullberg S; Wahlstrom J; Grunewald J; Brynedal B; Jagodic M; Ekstrom T; Ockinger J; Kular L
Corrigendum: AMERICAN JOURNAL OF HUMAN GENETICS. 2019;105(4):880

Distinct HLA Associations with Rheumatoid Arthritis Subsets Defined by Serological Subphenotype (vol 105, pg 616, 2019)

Terao C; Brynedal B; Chen Z; Jiang X; Westerlind H; Hansson M; Jakobsson P-J; Lundberg K; Skriner K; Serre G; Ronnelid J; Mathsson-Alm L; Brink M; Dahlqvist SR; Padyukov L; Gregersen PK; Barton A; Alfredsson L; Klareskog L; Raychaudhuri S
Preprint: BIORXIV. 2019

Understanding interactions between risk factors, and assessing the utility of the additive and multiplicative models through simulations

Diaz-Gallo L-M; Brynedal B; Westerlind H; Sandberg R; Ramsköld D
Conference publication: ANNALS OF THE RHEUMATIC DISEASES. 2019;78:A13

OCCUPATIONAL PHYSICAL WORKLOAD AND DEVELOPMENT OF ANTI-COLLAGEN TYPE II ANTIBODIES IN RHEUMATOID ARTHRITIS: RESULTS FROM THE SWEDISH EIRA POPULATION-BASED CASE-CONTROL STUDY

Pertsinidou E; Zeng P; Brynedal B; Manivel VA; Klareskog L; Mullazehi M; Saevarsdottir S; Bengtsson C; Alfredsson L; Ronnelid J
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2018;77:A33

CHARACTERISATION OF THE ANTIBODY RESPONSE TO A CITRULLINATED PEPTIDE DERIVED FROM PORPHYROMONAS GINGIVALIS PAD IN RA

Kharlamova N; Brynedal B; Sherina N; Eriksson K; Lindberg T; Hansson M; Israelsson L; Steen J; Malmstrom V; Alfredsson L; Amara K; Lundberg K
Preprint: BIORXIV. 2017

The association between the HLA-DRB1 shared epitope alleles and the risk of rheumatoid arthritis is influenced by massive gene-gene interactions

Diaz-Gallo L-M; Ramsköld D; Shchetynsky K; Folkersen L; Chemin K; Brynedal B; Uebe S; Okada Y; Alfredsson L; Klareskog L; Padyukov L
Letter: AMERICAN JOURNAL OF GASTROENTEROLOGY. 2016;111(8):1211-1213

HLA Associations Distinguish Collagenous From Lymphocytic Colitis

Westerlind H; Bonfiglio F; Mellander M-R; Huebenthal M; Brynedal B; Bjork J; Torkvist L; Padyukov L; Ohlsson B; Lofberg R; Hultcrantz R; Franke A; Bresso F; D'Amato M
Preprint: BIORXIV. 2016

Large-scale trans-eQTLs affect hundreds of transcripts and mediate patterns of transcriptional co-regulation Short: trans-eQTLs reveal patterns of transcriptional co-regulation

Brynedal B; Choi J; Raj T; Bjornson R; Stranger BE; Neale BM; Voight BF; Cotsapas C
Conference publication: ARTHRITIS & RHEUMATOLOGY. 2016;68

Specific Antibody Subphenotypes in Rheumatoid Arthritis Are Associated with Unique HLA-DRB1 Residues at Position 11

Terao C; Brynedal B; Chen Z; Jiang X; Westerlind H; Hansson M; Mathsson-Alm L; Jakobsson PJ; Skriner K; Serre G; Ronnelid J; Padyukov L; Worthington J; Alfredsson L; Klareskog L; Raychaudhuri S
Conference publication: ARTHRITIS & RHEUMATOLOGY. 2016;68

Antibody Mediated Immunity Drives Response to Methotrexate Treatment in Rheumatoid Arthritis Patients

Brynedal B; Westerlind H; Folkersen L; Padyukov L; Vivar N; Catrina AI; Klareskog L; Berg L
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2015;21:435-436

Genetic load in eleven distantly related individuals from an MS high risk area

Imrell K; Masterman T; Brynedal B; Lima I; Hillert J; Kockum I; Landtblom A-M
Preprint: ARXIV. 2014

Cross-phenotype meta-analysis reveals large-scale trans-eQTLs mediating patterns of transcriptional co-regulation

Brynedal B; Raj T; Stranger BE; Bjornson R; Neale BM; Voight BF; Cotsapas C
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2014;79(6):450

Human Leucocyte Antigen Genes and Interferon Beta Preparations Influence Risk of Developing Neutralizing Antidrug Antibodies in Multiple Sclerosis

Ryner ML; Link J; Fink K; Hermanrud C; Lima I; Brynedal B; Kockum I; Hillert J; Fogdell-Hahn A
Conference publication: HLA. 2014;84(1):109

HUMAN LEUKOCYTE ANTIGEN GENES AND INTERFERON BETA PREPARATIONS INFLUENCE RISK OF DEVELOPING NEUTRALIZING ANTI-DRUG ANTIBODIES IN MULTIPLE SCLEROSIS

Link J; Ryner ML; Fink K; Hermanrud C; Lima I; Brynedal B; Kockum I; Hillert J; Fogdell-Hahn A
Conference publication: NEUROLOGY. 2012;78:p05.121

Investigation of the Effect of Human Leukocyte Antigen on the Development of Neutralizing Antibodies in Interferon-beta Treated Patients with Multiple Sclerosis (*The First Three Authors Contributed Equally to This Work)

Fink K; Lundkvist M; Link J; Kockum I; Hermanrud C; Brynedal B; Hillert J; Fogdell-Hahn A
Conference publication: IMMUNOLOGY. 2012;137:663

Effect of HLA genotype on the development of neutralizing antibodies to interferon beta in patients with multiple sclerosis

Lundkvist M; Link J; Fink K; Hermanrud C; Brynedal B; Fogdell-Hahn A; Kockum I; Hillert J
Conference publication: JOURNAL OF NEUROLOGY. 2012;259:S149

HLA-DRB1*15 and HLA-A*02 are associated with higher risk of developing neutralising antibodies and clinically relevant titres against interferon-beta in multiple sclerosis

Link J; Lundkvist M; Fink K; Hermanrud C; Brynedal B; Fogdell-Hahn A; Kockum I; Hillert J
Conference publication: EUROPEAN JOURNAL OF NEUROLOGY. 2012;19:361

Preparation-specific genetically determined risk of developing neutralizing antibodies towards interferon-beta in patients with multiple sclerosis

Link J; Fink K; Lundkvist M; Brynedal B; Kockum I; Fogdell-Hahn A; Hillert J
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2011;17:S114

New evidence implicates IRF5 in the pathogenesis of multiple sclerosis

Bomfim IL; Wang C; Khademi M; Sandling J; Brynedal B; Lorentzen AR; Sondergaard HB; Oturai AB; Celius EG; Alfredsson L; Syvanen A-C; Kockum I; Olsson T; Hillert J
Conference publication: JOURNAL OF NEUROLOGY. 2011;258:196

Investigation of HLA genes in multiple sclerosis in Scandinavia

Link J; Kockum I; Lorentzen A; Lie BA; Celius EG; Schaffer M; Brynedal B; Harbo H; Hillert J
Editorial comment: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009;106(23):E58

Differential expression, and genetic association, of CD58 in Swedish multiple sclerosis patients

Brynedal B; Bomfim IL; Olsson T; Duvefelt K; Hillert J
Thesis / dissertation: 2009

On genetics and transcriptomics of multiple sclerosis

Brynedal, Boel
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2008;14:S189-S190

Human leukocyte antigen class I risks in multiple sclerosis: A rather than C

Link J; Lorentzen AR; Kockum I; Duvefelt K; Mero I-L; Celius EG; Harbo HF; Hillert J; Brynedal B
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2008;14:S60

Global expression profiling in multiple sclerosis: a disease of the central nervous system, but with relapses triggered in the periphery?

Brynedal B; Khademi M; Wallstroem E; Hillert J; Olsson TP; Duvefelt K
Conference publication: EUROPEAN JOURNAL OF NEUROLOGY. 2007;14:22

The impact of HLA-A and HLA-DRB1 alleles on age at onset, disease course and severity in Scandinavian multiple sclerosis patients

Smestad C; Brynedal B; Jonasdottir G; Lorentzen AR; Masterman T; Akesson E; Spurkland A; Lie BA; Palmgren J; Celius EG; Hillert J; Harbo HF
Conference publication: HLA. 2006;67(6):456

Genetic variation of HLA-A alters the susceptibility to multiple sclerosis

Brynedal B; Duvefelt K; Jonasdottir G; Roos IM; Akesson E; Hillert J
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Anställningar

Epidemiolog, Epidemiologi och folkhälsa, Centrum för epidemiologi och samhällsmedicin, Region Stockholm, 2019-
Anknuten till Forskning, Global folkhälsa, Karolinska Institutet, 2024-2027

Examina och utbildning

Docent, epidemiologi, Karlinska Institutet, 2022
Medicine Doktorsexamen, Institutionen för klinisk neurovetenskap, Karolinska Institutet, 2009

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