Boel Brynedal

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Article: PREVENTIVE MEDICINE REPORTS. 2024;44:102806
Predicting new cases of hypertension in Swedish primary care with a machine learning tool
Norrman A; Hasselstrom J; Ljunggren G; Wachtler C; Eriksson J; Kahan T; Wandell P; Gudjonsdottir H; Lindblom S; Ruge T; Rosenblad A; Brynedal B; Carlsson AC
Journal article: PREVENTIVE MEDICINE REPORTS. 2024;44:102806
Predicting new cases of hypertension in Swedish primary care with a machine learning tool.
Norrman A; Hasselström J; Ljunggren G; Wachtler C; Eriksson J; Kahan T; Wändell P; Gudjonsdottir H; Lindblom S; Ruge T; Rosenblad A; Brynedal B; Carlsson AC
Article: AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. 2024;231(1):107.e1-107.e19
Mode of delivery and subsequent self-perceived sexual life satisfaction: a population-based cohort study
Zweygberg AL; Martin FZ; Brynedal B; Lindholm ES; Kosidou K; Ahlqvist VH; Magnusson C
Article: PREVENTIVE MEDICINE. 2024;183:107969
The influence of the COVID-19 pandemic on physical activity in Stockholm County - Evidence from time series models of smartphone measured daily steps data spanning over 3 years
Zhou M; Gebreslassie M; Leon APD; Tynelius P; Ahlqvist VH; Dahlen M; Berglind D; Lager A; Brynedal B
Article: BMC MEDICINE. 2024;22(1):168
Undiagnosed type 2 diabetes is common - intensified screening of established risk groups is imperative in Sweden: the SDPP cohort
Gudjonsdottir H; Tynelius P; Stattin NS; Mendez DY; Lager A; Brynedal B
Journal article: NEURO-ONCOLOGY PRACTICE. 2024;:npae047
Health-related quality of life in surgically treated asymptomatic meningioma patients: A population-based matched cohort study
Naslund O; Jakobsson S; Thurin E; Skoglund T; Pettersson-Segerlind J; Brynedal B; Jakola AS; Bartek Jr J
Article: ENVIRONMENTAL RESEARCH. 2023;239(Pt 1):117230
Multiple myeloma risk in relation to long-term air pollution exposure - A pooled analysis of four European cohorts
Hvidtfeldt UA; Chen J; Rodopoulou S; Strak M; de Hoogh K; Bellander T; Brandt JO; Forastiere F; Brynedal B; Hertel O; Hoffmann B; Katsouyanni K; Ketzel M; Leander K; Magnusson PKE; Nagel G; Pershagen G; Rizzuto D; Samoli E; So R; Stafoggia M; Onneland AT; Weinmayr G; Wolf K; Zitt E; Brunekreef B; Hoek G; Raaschou-Nielsen O
Article: BJPSYCH OPEN. 2023;9(6):e205
Migration background, eating disorder symptoms and healthcare service utilisation: findings from the Stockholm Public Health Cohort
Strand M; Baarnhielm S; Fredlund P; Brynedal B; Welch E
Article: SCIENTIFIC REPORTS. 2023;13(1):10058
Peripheral blood cellular dynamics of rheumatoid arthritis treatment informs about efficacy of response to disease modifying drugs
Hedman AK; Winter E; Yoosuf N; Benita Y; Berg L; Brynedal B; Folkersen L; Klareskog L; Maciejewski M; Sirota-Madi A; Spector Y; Ziemek D; Padyukov L; Shen-Orr SS; Jelinsky SA
Article: CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION. 2023;32(1):105-113
Breast Cancer Incidence in Relation to Long-Term Low-Level Exposure to Air Pollution in the ELAPSE Pooled Cohort
Hvidtfeldt UA; Chen J; Rodopoulou S; Strak M; de Hoogh K; Andersen ZJ; Bellander T; Brandt J; Fecht D; Forastiere F; Gulliver J; Hertel O; Hoffmann BH; Katsouyanni K; Ketzel M; Brynedal B; Leander K; Ljungman PLS; Magnusson PKE; Nagel G; Pershagen G; Rizzuto D; Boutron-Ruault M-C; Samoli E; So R; Stafoggia M; Tjonneland A; Vermeulen R; Verschuren WMM; Weinmayr G; Wolf K; Zhang J; Zitt E; Brunekreef B; Hoek G; Raaschou-Nielsen O
Article: FRONTIERS IN MEDICINE. 2023;10:1146353
Molecular signature of methotrexate response among rheumatoid arthritis patients
Brynedal B; Yoosuf N; Ulfarsdottir TB; Ziemek D; Maciejewski M; Folkersen L; Westerlind H; Mueller M; Sahlstrom P; Jelinsky SA; Hensvold A; Padyukov L; Pomiano NV; Catrina A; Klareskog L; Berg L
Article: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 2022;51(6):e401-e413
Cohort Profile: The Stockholm Diabetes Prevention Programme (SDPP)
Gudjonsdottir H; Tynelius P; Fors S; Mendez DY; Gebreslassie M; Zhou M; Carlsson AC; Svefors P; Wandell P; Ostenson C-G; Brynedal B; Lager A
Article: BMC MEDICINE. 2022;20(1):356
Characterization of data-driven clusters in diabetes-free adults and their utility for risk stratification of type 2 diabetes
Mendez DY; Zhou M; Lagerros YT; Velasco DVG; Tynelius P; Gudjonsdottir H; de Leon AP; Eeg-Olofsson K; Ostenson C-G; Brynedal B; Aguilar Salinas CA; Ebbevi D; Lager A
Article: ENVIRONMENT INTERNATIONAL. 2022;166:107341
Exposure to surrounding greenness and natural-cause and cause-specific mortality in the ELAPSE pooled cohort
Bereziartua A; Chen J; de Hoogh K; Rodopoulou S; Andersen ZJ; Bellander T; Brandt J; Fecht D; Forastiere F; Gulliver J; Hertel O; Hoffmann B; Hvidtfeldt UA; Verschuren WMM; Joeckel K-H; Jorgensen JT; Katsouyanni K; Ketzel M; Krog NH; Brynedal B; Leander K; Liu S; Ljungman P; Faure E; Magnusson PKE; Nagel G; Pershagen G; Peters A; Raaschou-Nielsen O; Renzi M; Rizzuto D; Samoli E; van der Schouw YT; Schramm S; Severi G; Stafoggia M; Strak M; Sorensen M; Tjonneland A; Weinmayr G; Wolf K; Zitt E; Brunekreef B; Hoek G
Article: RHEUMATOLOGY. 2022;61(4):1680-1689
Early prediction of clinical response to anti-TNF treatment using multi-omics and machine learning in rheumatoid arthritis
Yoosuf N; Maciejewski M; Ziemek D; Jelinsky SA; Folkersen L; Muller M; Sahlstrom P; Vivar N; Catrina A; Berg L; Klareskog L; Padyukov L; Brynedal B
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:804822
Antibodies to a Citrullinated Porphyromonas gingivalis Epitope Are Increased in Early Rheumatoid Arthritis, and Can Be Produced by Gingival Tissue B Cells: Implications for a Bacterial Origin in RA Etiology
Sherina N; de Vries C; Kharlamova N; Sippl N; Jiang X; Brynedal B; Kindstedt E; Hansson M; Mathsson-Alm L; Israelsson L; Stalesen R; Saevarsdottir S; Holmdahl R; Hensvold A; Johannsen G; Eriksson K; Sallusto F; Catrina AI; Roennelid J; Groenwall C; Yucel-Lindberg T; Alfredsson L; Klareskog L; Piccoli L; Malmstroem V; Amara K; Lundberg K
Article: MULTIPLE SCLEROSIS JOURNAL. 2021;27(7):1014-1026
Methylome and transcriptome signature of bronchoalveolar cells from multiple sclerosis patients in relation to smoking
Ringh MV; Hagemann-Jensen M; Needhamsen M; Kullberg S; Wahlstrom J; Grunewald J; Brynedal B; Jagodic M; Ekstrom TJ; Ockinger J; Kular L
Article: PLOS ONE. 2021;16(4):e0250282
Understanding interactions between risk factors, and assessing the utility of the additive and multiplicative models through simulations
Diaz-Gallo L-M; Brynedal B; Westerlind H; Sandberg R; Ramskold D
Article: ARTHRITIS RESEARCH & THERAPY. 2020;22(1):170
Presence of autoantibodies in "seronegative" rheumatoid arthritis associates with classical risk factors and high disease activity
Reed E; Hedstrom AK; Hansson M; Mathsson-Alm L; Brynedal B; Saevarsdottir S; Cornillet M; Jakobsson P-J; Holmdahl R; Skriner K; Serre G; Alfredsson L; Ronnelid J; Lundberg K
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2019;105(3):616-624
Distinct HLA Associations with Rheumatoid Arthritis Subsets Defined by Serological Subphenotype
Terao C; Brynedal B; Chen Z; Jiang X; Westerlind H; Hansson M; Jakobsson P-J; Lundberg K; Skriner K; Serre G; Ronnelid J; Mathsson-Alm L; Brink M; Dahlqvist SR; Padyukov L; Gregersen PK; Barton A; Alfredsson L; Klareskog L; Raychaudhuri S
Article: EBIOMEDICINE. 2019;46:290-304
Tobacco smoking induces changes in true DNA methylation, hydroxymethylation and gene expression in bronchoalveolar lavage cells
Ringh MV; Hagemann-Jensen M; Needhamsen M; Kular L; Breeze CE; Sjoholm LK; Slavec L; Kullberg S; Wahlstrom J; Grunewald J; Brynedal B; Liu Y; Almgren M; Jagodic M; Ockinger J; Ekstrom TJ
Article: ANNALS OF THE RHEUMATIC DISEASES. 2018;77(10):1454-1462
Systematic approach demonstrates enrichment of multiple interactions between non-HLA risk variants and HLA-DRB1 risk alleles in rheumatoid arthritis
Diaz-Gallo L-M; Ramskold D; Shchetynsky K; Folkersen L; Chemin K; Brynedal B; Uebe S; Okada Y; Alfredsson L; Klareskog L; Padyukov L
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2017;100(4):581-591
Large-Scale trans-eQTLs Affect Hundreds of Transcripts and Mediate Patterns of Transcriptional Co-regulation
Brynedal B; Choi J; Raj T; Bjornson R; Stranger BE; Neale BM; Voight BF; Cotsapas C
Article: GUT. 2017;66(3):421-428
Dense genotyping of immune-related loci identifies HLA variants associated with increased risk of collagenous colitis
Westerlind H; Mellander M-R; Bresso F; Munch A; Bonfiglio F; Assadi G; Rafter J; Huebenthal M; Lieb W; Kallberg H; Brynedal B; Padyukov L; Halfvarson J; Torkvist L; Bjork J; Andreasson A; Agreus L; Almer S; Miehlke S; Madisch A; Ohlsson B; Lofberg R; Hultcrantz R; Franke A; D'Amato M
Article: MOLECULAR MEDICINE. 2016;22:322-328
Integration of Known DNA, RNA and Protein Biomarkers Provides Prediction of Anti-TNF Response in Rheumatoid Arthritis: Results from the COMBINE Study
Folkersen L; Brynedal B; Diaz-Gallo LM; Ramskold D; Shchetynsky K; Westerlind H; Sundstrom Y; Schepis D; Hensvold A; Vivar N; Eloranta M-L; Ronnblom L; Brunak S; Malmstrom V; Catrina A; Moerch UGW; Klareskog L; Padyukov L; Berg L
Journal article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(Suppl 2):146
OP0234 Rheumatoid Arthritis Subsets Defined by Sub-Specificities of Anti-Citrullinated Antibodies (ACPAS) Have Unique HLA Associations
Brynedal B; Terao C; Chen Z; Jiang X; Westerlind H; Hansson M; Jakobsson P-J; Skriner K; Serre G; Rönnelid J; Padyukov L; Gregersen P; Worthington J; Alfredsson L; Raychaudhuri S; Klareskog L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2015;74(4):762-768
Genetic risk scores and number of autoantibodies in patients with rheumatoid arthritis
Maehlen MT; Olsen IC; Andreassen BK; Viken MK; Jiang X; Alfredsson L; Kallberg H; Brynedal B; Kurreeman F; Daha N; Toes R; Zhernakova A; Gutierrez-Achury J; de Bakker PIW; Martin J; Teruel M; Gonzalez-Gay MA; Rodriguez-Rodriguez L; Balsa A; Uhlig T; Kvien TK; Lie BA
Journal article: NEUROLOGY. 2014;82(10_supplement)
HLA Genes and Interferon-beta Preparations Influence Risk of Developing Neutralizing Anti-Drug Antibodies in Multiple Sclerosis (P1.213)
Fink K; Link J; Lundkvist M; Hermanrud C; Lima I; Brynedal B; Kockum I; Hillert J; Fogdell-Hahn A
Article: PLOS ONE. 2014;9(3):e90479
Human Leukocyte Antigen Genes and Interferon Beta Preparations Influence Risk of Developing Neutralizing Anti-Drug Antibodies in Multiple Sclerosis
Link J; Ryner ML; Fink K; Hermanrud C; Lima I; Brynedal B; Kockum I; Hillert J; Fogdell-Hahn A
Article: PLOS ONE. 2012;7(5):e36779
Importance of Human Leukocyte Antigen (HLA) Class I and II Alleles on the Risk of Multiple Sclerosis
Link J; Kockum I; Lorentzen AR; Lie BA; Celius EG; Westerlind H; Schaffer M; Alfredsson L; Olsson T; Brynedal B; Harbo HF; Hillert J
Article: JOURNAL OF NEUROIMMUNOLOGY. 2011;237(1-2):98-100
No influence on disease progression of non-HLA susceptibility genes in MS
Lundstrom W; Greiner E; Lundmark F; Westerlind H; Smestad C; Lorentzen AR; Kockum I; Link J; Brynedal B; Celius EG; Harbo HF; Masterman T; Hillert J
Journal article: FUTURE NEUROLOGY. 2011;6(4):511-519
Entering a new phase of multiple sclerosis genetic epidemiology
Brynedal B; Hillert J
Article: JOURNAL OF IMMUNOLOGY. 2011;186(3):1338-1342
Cutting edge: TIGIT has T cell-intrinsic inhibitory functions.
Joller N; Hafler JP; Brynedal B; Kassam N; Spoerl S; Levin SD; Sharpe AH; Kuchroo VK
Article: JOURNAL OF NEUROIMMUNOLOGY. 2010;226(1-2):172-176
Two HLA class I genes independently associated with multiple sclerosis
Link J; Lorentzen AR; Kockum I; Duvefelt K; Lie BA; Celius EG; Harbo HF; Hillert J; Brynedal B
Article: GENES AND IMMUNITY. 2010;11(5):397-405
IL12A, MPHOSPH9/CDK2AP1 and RGS1 are novel multiple sclerosis susceptibility loci
Esposito F; Patsopoulos NA; Cepok S; Kockum I; Leppa V; Booth DR; Heard RN; Stewart GJ; Cox M; Scott RJ; Lechner-Scott J; Goris A; Dobosi R; Dubois B; Rioux JD; Oturai AB; Sondergaard HB; Sellebjerg F; Sorensen PS; Reunanen M; Koivisto K; Cournu-Rebeix I; Fontaine B; Winkelmann J; Gieger C; Infante-Duarte C; Zipp F; Bergamaschi L; Leone M; Bergamaschi R; Cavalla P; Lorentzen AR; Mero I-L; Celius EG; Harbo HF; Spurkland A; Comabella M; Brynedal B; Alfredsson L; Bernardinelli L; Robertson NP; Hawkins CP; Barcellos LF; Beecham G; Bush W; Cree BAC; Daly MJ; Ivinson AJ; Aubin C; Compston A; D'Alfonso S; Haines JL; Hauser SL; Hemmer B; Hillert J; McCauley JL; Oksenberg J; Olsson T; Palotie A; Peltonen L; Pericak-Vance MA; Saarela J; Sawcer SJ; Stranger B; Boneschi FM; Comi G; Hafler DA; de Bakker PIW; De Jager PL
Article: JOURNAL OF NEUROIMMUNOLOGY. 2010;220(1-2):120-124
MGAT5 alters the severity of multiple sclerosis
Brynedal B; Wojcik J; Esposito F; Debailleul V; Yaouanq J; Martinelli-Boneschi F; Edan G; Comi G; Hillert J; Abderrahim H
Article: NEUROBIOLOGY OF DISEASE. 2010;37(3):613-621
Gene expression profiling in multiple sclerosis: A disease of the central nervous system, but with relapses triggered in the periphery?
Brynedal B; Khademi M; Wallstrom E; Hillert J; Olsson T; Duvefelt K
Article: RESPIRATORY RESEARCH. 2010;11(1):25
Different HLA-DRB1 allele distributions in distinct clinical subgroups of sarcoidosis patients
Grunewald J; Brynedal B; Darlington P; Nisell M; Cederlund K; Hillert J; Eklund A
Article: JOURNAL OF INTERNAL MEDICINE. 2008;264(5):433-441
A common haplotype of the C-C chemokine receptor 2 gene and HLA-DRB1*0301 are independent genetic risk factors for Lofgren's syndrome
Spagnolo P; Sato H; Grunewald J; Brynedal B; Hillert J; Mana J; Wells AU; Eklund A; Welsh KI; du Bois RM
Article: EUROPEAN JOURNAL OF NEUROLOGY. 2007;14(8):835-840
The impact of HLA-A and-DRB1 on age at onset, disease course and severity in Scandinavian multiple sclerosis patients
Smestad C; Brynedal B; Jonasdottir G; Lorentzen AR; Masterman T; Akesson E; Spurkland A; Lie BA; Palmgren J; Celius EG; Hillert J; Harbo HF
Article: PLOS ONE. 2007;2(7):e664
HLA-A Confers an HLA-DRB1 Independent Influence on the Risk of Multiple Sclerosis
Brynedal B; Duvefelt K; Jonasdottir G; Roos IM; Akesson E; Palmgren J; Hillert J
Article: JOURNAL OF NEUROIMMUNOLOGY. 2005;167(1-2):210-214
Increased levels of APRIL (a proliferation-inducing ligand) mRNA in multiple sclerosis
Thangarajh M; Masterman T; Rot U; Duvefelt K; Brynedal B; Karrenbauer VD; Hillert J
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All other publications

Preprint: RESEARCH SQUARE. 2022
Peripheral blood cellular dynamics of Rheumatoid arthritis treatment informs about efficacy of response to disease modifying drugs
Jelinsky SA; Hedman ÅK; Winter E; Yoosuf N; Benita Y; Berg L; Brynedal B; Folkersen L; Klareskog L; Maciejewski M; Sirota-Madi A; Spector Y; Ziemek D; Padyukov L; Shen-Orr SS
Preprint: MEDRXIV. 2021
Identification of loci genetically associated with antibodies to specific sets of citrullinated peptides in rheumatoid arthritis patients
Shchetynsky K; Brynedal B; Ramsköld D; Israelsson L; Hansson M; Mathsson-Alm L; Rönnelid J; Rheumatoid Arthritis Consortium International (RAC; Viatte S; Holmdahl R; Catrina A; Alfredsson L; Malmström V; Klareskog L; Gomez-Cabrero D; Padyukov L
Preprint: RESEARCH SQUARE. 2021
Early Prediction of Clinical Response to Anti-TNF Treatment using Multi-omics and Machine Learning in Rheumatoid Arthritis
Yoosuf N; Maciejewski M; Ziemek D; Jelinsky SA; Folkersen L; Müller M; Sahlström P; Vivar N; Catrina A; Berg L; Klareskog L; Padyukov L; Brynedal B
Letter: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2020;38(5):1029-1030
Occupational physical workload and development of anti-collagen type II antibodies in rheumatoid arthritis: results from the Swedish EIRA population-based case-control study
Zeng P; Pertsinidou E; Brynedal B; Manivel VA; Klareskog L; Mullazehi M; Saevarsdottir S; Bengtsson C; Alfredsson L; Ronnelid J
Preprint: RESEARCH SQUARE. 2020
Molecular Biomarkers of Anti-TNF Response in Patients with Rheumatoid Arthritis
Yoosuf N; Maciejewski M; Ziemek D; Jelinsky S; Folkersen L; Müller M; Sahlström P; Vivar N; Catrina A; Berg L; Klareskog L; Padyukov L; Brynedal B
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2020;26(3_SUPPL):583
Methylome and transcriptome signature of bronchoalveolar cells from multiple sclerosis patients in relation to smoking
Ringh M; Hagemann-Jensen M; Needhamsen M; Kullberg S; Wahlstrom J; Grunewald J; Brynedal B; Jagodic M; Ekstrom T; Ockinger J; Kular L
Corrigendum: AMERICAN JOURNAL OF HUMAN GENETICS. 2019;105(4):880
Distinct HLA Associations with Rheumatoid Arthritis Subsets Defined by Serological Subphenotype (vol 105, pg 616, 2019)
Terao C; Brynedal B; Chen Z; Jiang X; Westerlind H; Hansson M; Jakobsson P-J; Lundberg K; Skriner K; Serre G; Ronnelid J; Mathsson-Alm L; Brink M; Dahlqvist SR; Padyukov L; Gregersen PK; Barton A; Alfredsson L; Klareskog L; Raychaudhuri S
Preprint: BIORXIV. 2019
Understanding interactions between risk factors, and assessing the utility of the additive and multiplicative models through simulations
Diaz-Gallo L-M; Brynedal B; Westerlind H; Sandberg R; Ramsköld D
Conference publication: ANNALS OF THE RHEUMATIC DISEASES. 2019;78:A13
OCCUPATIONAL PHYSICAL WORKLOAD AND DEVELOPMENT OF ANTI-COLLAGEN TYPE II ANTIBODIES IN RHEUMATOID ARTHRITIS: RESULTS FROM THE SWEDISH EIRA POPULATION-BASED CASE-CONTROL STUDY
Pertsinidou E; Zeng P; Brynedal B; Manivel VA; Klareskog L; Mullazehi M; Saevarsdottir S; Bengtsson C; Alfredsson L; Ronnelid J
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2018;77:A33
CHARACTERISATION OF THE ANTIBODY RESPONSE TO A CITRULLINATED PEPTIDE DERIVED FROM PORPHYROMONAS GINGIVALIS PAD IN RA
Kharlamova N; Brynedal B; Sherina N; Eriksson K; Lindberg T; Hansson M; Israelsson L; Steen J; Malmstrom V; Alfredsson L; Amara K; Lundberg K
Preprint: BIORXIV. 2017
The association between the HLA-DRB1 shared epitope alleles and the risk of rheumatoid arthritis is influenced by massive gene-gene interactions
Diaz-Gallo L-M; Ramsköld D; Shchetynsky K; Folkersen L; Chemin K; Brynedal B; Uebe S; Okada Y; Alfredsson L; Klareskog L; Padyukov L
Letter: AMERICAN JOURNAL OF GASTROENTEROLOGY. 2016;111(8):1211-1213
HLA Associations Distinguish Collagenous From Lymphocytic Colitis
Westerlind H; Bonfiglio F; Mellander M-R; Huebenthal M; Brynedal B; Bjork J; Torkvist L; Padyukov L; Ohlsson B; Lofberg R; Hultcrantz R; Franke A; Bresso F; D'Amato M
Preprint: BIORXIV. 2016
Large-scale trans-eQTLs affect hundreds of transcripts and mediate patterns of transcriptional co-regulation Short: trans-eQTLs reveal patterns of transcriptional co-regulation
Brynedal B; Choi J; Raj T; Bjornson R; Stranger BE; Neale BM; Voight BF; Cotsapas C
Conference publication: ARTHRITIS & RHEUMATOLOGY. 2016;68
Specific Antibody Subphenotypes in Rheumatoid Arthritis Are Associated with Unique HLA-DRB1 Residues at Position 11
Terao C; Brynedal B; Chen Z; Jiang X; Westerlind H; Hansson M; Mathsson-Alm L; Jakobsson PJ; Skriner K; Serre G; Ronnelid J; Padyukov L; Worthington J; Alfredsson L; Klareskog L; Raychaudhuri S
Conference publication: ARTHRITIS & RHEUMATOLOGY. 2016;68
Antibody Mediated Immunity Drives Response to Methotrexate Treatment in Rheumatoid Arthritis Patients
Brynedal B; Westerlind H; Folkersen L; Padyukov L; Vivar N; Catrina AI; Klareskog L; Berg L
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2015;21:435-436
Genetic load in eleven distantly related individuals from an MS high risk area
Imrell K; Masterman T; Brynedal B; Lima I; Hillert J; Kockum I; Landtblom A-M
Preprint: ARXIV. 2014
Cross-phenotype meta-analysis reveals large-scale trans-eQTLs mediating patterns of transcriptional co-regulation
Brynedal B; Raj T; Stranger BE; Bjornson R; Neale BM; Voight BF; Cotsapas C
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2014;79(6):450
Human Leucocyte Antigen Genes and Interferon Beta Preparations Influence Risk of Developing Neutralizing Antidrug Antibodies in Multiple Sclerosis
Ryner ML; Link J; Fink K; Hermanrud C; Lima I; Brynedal B; Kockum I; Hillert J; Fogdell-Hahn A
Conference publication: HLA. 2014;84(1):109
HUMAN LEUKOCYTE ANTIGEN GENES AND INTERFERON BETA PREPARATIONS INFLUENCE RISK OF DEVELOPING NEUTRALIZING ANTI-DRUG ANTIBODIES IN MULTIPLE SCLEROSIS
Link J; Ryner ML; Fink K; Hermanrud C; Lima I; Brynedal B; Kockum I; Hillert J; Fogdell-Hahn A
Conference publication: NEUROLOGY. 2012;78:p05.121
Investigation of the Effect of Human Leukocyte Antigen on the Development of Neutralizing Antibodies in Interferon-beta Treated Patients with Multiple Sclerosis (*The First Three Authors Contributed Equally to This Work)
Fink K; Lundkvist M; Link J; Kockum I; Hermanrud C; Brynedal B; Hillert J; Fogdell-Hahn A
Conference publication: IMMUNOLOGY. 2012;137:663
Effect of HLA genotype on the development of neutralizing antibodies to interferon beta in patients with multiple sclerosis
Lundkvist M; Link J; Fink K; Hermanrud C; Brynedal B; Fogdell-Hahn A; Kockum I; Hillert J
Conference publication: EUROPEAN JOURNAL OF NEUROLOGY. 2012;19:361
Preparation-specific genetically determined risk of developing neutralizing antibodies towards interferon-beta in patients with multiple sclerosis
Link J; Fink K; Lundkvist M; Brynedal B; Kockum I; Fogdell-Hahn A; Hillert J
Conference publication: JOURNAL OF NEUROLOGY. 2012;259:S149
HLA-DRB1*15 and HLA-A*02 are associated with higher risk of developing neutralising antibodies and clinically relevant titres against interferon-beta in multiple sclerosis
Link J; Lundkvist M; Fink K; Hermanrud C; Brynedal B; Fogdell-Hahn A; Kockum I; Hillert J
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2011;17:S114
New evidence implicates IRF5 in the pathogenesis of multiple sclerosis
Bomfim IL; Wang C; Khademi M; Sandling J; Brynedal B; Lorentzen AR; Sondergaard HB; Oturai AB; Celius EG; Alfredsson L; Syvanen A-C; Kockum I; Olsson T; Hillert J
Conference publication: JOURNAL OF NEUROLOGY. 2011;258:196
Investigation of HLA genes in multiple sclerosis in Scandinavia
Link J; Kockum I; Lorentzen A; Lie BA; Celius EG; Schaffer M; Brynedal B; Harbo H; Hillert J
Editorial comment: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009;106(23):E58
Differential expression, and genetic association, of CD58 in Swedish multiple sclerosis patients
Brynedal B; Bomfim IL; Olsson T; Duvefelt K; Hillert J
Thesis / dissertation: 2009
On genetics and transcriptomics of multiple sclerosis
Brynedal, Boel
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2008;14:S189-S190
Human leukocyte antigen class I risks in multiple sclerosis: A rather than C
Link J; Lorentzen AR; Kockum I; Duvefelt K; Mero I-L; Celius EG; Harbo HF; Hillert J; Brynedal B
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2008;14:S60
Global expression profiling in multiple sclerosis: a disease of the central nervous system, but with relapses triggered in the periphery?
Brynedal B; Khademi M; Wallstroem E; Hillert J; Olsson TP; Duvefelt K
Conference publication: EUROPEAN JOURNAL OF NEUROLOGY. 2007;14:22
The impact of HLA-A and HLA-DRB1 alleles on age at onset, disease course and severity in Scandinavian multiple sclerosis patients
Smestad C; Brynedal B; Jonasdottir G; Lorentzen AR; Masterman T; Akesson E; Spurkland A; Lie BA; Palmgren J; Celius EG; Hillert J; Harbo HF
Conference publication: HLA. 2006;67(6):456
Genetic variation of HLA-A alters the susceptibility to multiple sclerosis
Brynedal B; Duvefelt K; Jonasdottir G; Roos IM; Akesson E; Hillert J
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Grants

Notification of the use of return grants for awarded postdoctoral fellowships in medicine or science and technology
Swedish Research Council
1 December 2012 - 30 November 2013
Characterization of the functional relevance of genetic risk variants for autoimmunity in regulatory T cells.
Swedish Research Council
1 January 2010 - 31 December 2011

Employments

Epidemiologist, Epidemiology and public health, Centre for Epidemiology and Community Medicine, Region Stockholm, 2019-
Affiliated to Research, Department of Global Public Health, Karolinska Institutet, 2024-2027

Degrees and Education

Docent, Karlinska Institutet, 2022
Degree Of Doctor Of Philosophy, Department of Clinical Neuroscience, Karolinska Institutet, 2009

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