Apostolos Bossios | Karolinska Institutet

Om mig
Publikationer
Forskningsbidrag
CV
Populärvetenskap och samverkan

Om mig

Docent i lungsjukdomar och överläkare inom lungmedicin vid Karolinska Universitetssjukhuset, Huddinge.
Forskargruppsledare vid IMM och CMM, Karolinska Institutet och Karolinska Universitetssjukhuset.

Lär mer på min engelska profilsida
sida https://staff.ki.se/people/apostolos-bossios ;

Artiklar

Article: PULMONOLOGY. 2025;31(1):2532980
Daily digital biomarkers in the follow-up and clustering of patients with asthma
Sousa-Pinto B; Schleich F; Louis G; Gemicioglu B; Kvedariene V; Regateiro FS; Chaves Loureiro C; Taborda-Barata L; Amaral R; Anto JM; Bedbrook A; Czarlewski W; Ansotegui IJ; Bergmann K-C; Bonini M; Bossios A; Boulet L-P; Braido F; Brightling C; Brusselle G; Brussino L; Canonica GW; Cruz AA; Haahtela T; Heaney LG; Hyland M; Ivancevich JC; Klimek L; Kulus M; Kuna P; Kupczyk M; Larenas-Linnemann DE; Makris M; Marques-Cruz M; Gil-Mata S; Morais-Almeida M; Niedoszytko M; Ollert M; Papadopoulos NG; Patella V; Pfaar O; Porsbjerg C; Puggioni F; Quirce S; Robalo Cordeiro C; Roche N; Samolinski B; Sastre J; Scichilone N; Skrgat S; Toppila-Salmi S; Usmani OS; Valiulis A; Gradauskiene B; Koyuncu IV; Ventura MT; Vieira RJ; Yorgancioglu A; Fonseca JA; Zuberbier T; Petre B; Louis R; Bousquet J
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2025;20:273-286
Chronic Airflow Limitation, Lower Respiratory Symptoms, COPD and Chronic Rhinosinusitis in a Middle-Aged Population: The Swedish CArdioPulmonary bioImage Study (SCAPIS). A Link Between the Lower and Upper Airways
Andersson A; Bergqvist J; Schioler L; Bossios A; Farnebo L; Holmlund T; Janson C; Keceli S; Ljunggren M; Malinovschi A; Memarian E; Nihlen U; Nilsson PM; Pesonen I; Sjostrom M; Stenfors N; Sundbom F; Werner M; Toren K; Skold M; Hellgren J
Article: LANCET RESPIRATORY MEDICINE. 2025;13(10):911-920
Symptoms, risk of future exacerbations, and response to long-term macrolide treatment in bronchiectasis: an observational study
Sibila O; Stobo J; Perea L; Gao Y-H; Xu J-F; Lind H; Viligorska K; Spinou A; Polverino E; Ringshausen FC; Vendrell M; Burgel P-R; Haworth CS; Loebinger MR; Lorent N; Dhar R; Choi H; Chotirmall SH; De Soyza A; Hurst JR; Brown JS; van der Eerden M; Kauppi P; Johnson E; Mendez R; Dimakou K; Bossios A; Torres A; Blasi F; Shteinberg M; Elborn SJ; Goeminne PC; Aliberti S; Jayaram L; Karalus N; Taylor SL; Martin ML; Burr L; Wong C; Terpstra L; Altenburg J; Boersma W; Chalmers J
Article: ERJ OPEN RESEARCH. 2025;11(5):00023-2025
Preserved ratio impaired spirometry, dysanapsis and airflow obstruction with low forced expiratory volume in 1 s in childhood asthma
Stridsman C; Backman H; Vanfleteren LEGW; Asarnoj A; Ljungberg H; Lindberg A; Bossios A; Konradsen JR
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE. 2025;13(9):2390-2396
Artificial Intelligence-Generated Answers to Patients' Questions on Asthma: The Artificial Intelligence Responses on Asthma Study
Nigro M; Aliverti A; Angelucci A; Braido F; Canonica GW; Bossios A; Pinnock H; Boyd J; Powell P; Aliberti S; Artificial IRAST
Article: ALLERGY. 2025;80(9):2541-2556
High-Dimensional Analysis of Type 2 Lymphocyte Dynamics During Mepolizumab or Dupilumab Treatment in Severe Asthma
Wirth L; Weigel W; Stamper CT; Kolmert J; de Souza Ferreira S; Hammer Q; Sparreman Mikus M; Theorell J; Andersson L; Lantz A-S; Wallen-Nielsen E; Petren A; Wheelock CE; Bossios A; Lazarinis N; Malinovschi A; Janson C; Dahlen B; Hochdorfer T; Tibbitt CA; Dahlen S-E; Yasinska V; Mjosberg J
Article: FRONTIERS IN PUBLIC HEALTH. 2025;13:1581460
The energy-health-environment nexus: assessing the transboundary impacts of coal-fired power plants
Dhar R; Sarkar S; Luo C; Anand M; Dasgupta S; Neogi U; Bossios A; Zamir R; Shoeb M; Routh J
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE. 2025;13(7):1609-1619.e5
Use of High-Dose Inhaled Corticosteroids and Risk of Corticosteroid-Related Adverse Events in Asthma Findings From the NORDSTAR Cohort
von Bulow A; Hansen S; Sandin P; Cooper A; Ernstsson O; Geale K; Lehtimaki L; Ulrik C; Aarli BB; Ilmarinen P; Packham S; Hassan G; Sverrild A; Backman H; Karjalainen J; Backer V; Altraja A; Kauppi P; Yasinska V; Kilpelainen M; Viinanen A; Martin-Schmid J; Bossios A; Porsbjerg C; Kankaanranta H; Janson C
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2025;156(1):118-128
Nasal production of IL-26 involving T cells in smokers with and without chronic obstructive pulmonary disease
Arebro J; Pournaras N; Ramos-Ramirez P; Cardenas EI; Bandeira E; Che KF; Brundin B; Bossios A; Karimi R; Nyren S; Stjarne P; Skold M; Linden A
Article: ALLERGOLOGY INTERNATIONAL. 2025;74(3):445-452
Impact of allergic symptoms on work productivity in allergic rhinitis: A MASK-air direct patient data study.
Vieira RJ; Pereira AM; Kupczyk M; Regateiro FS; Larenas-Linnemann DE; Toppila-Salmi S; Iinuma T; Kuna P; Cruz AA; Brussino L; Gemicioglu B; Samolinski B; Taborda-Barata L; Ventura MT; Kvedariene V; Klimek L; Pfaar O; Zuberbier T; Azevedo LF; Fonseca JA; Bousquet J; Sousa-Pinto B; MASK-air think tank
Journal article: ANNALS OF THE RHEUMATIC DISEASES. 2025;84:857-858
POS0676 RED FLAGS RAISING SUSPICION OF EOSINOPHILIC GRANULOMATOSIS WITH POLYANGIITIS (EGPA): RESULTS FROM THE EUROPEAN EGPAWARE DELPHI STUDY
Hellmich B; Bossios A; Domingo-Rivas C; Emmi G; Ponte C; Solans-Laque MR; Rúa-Figueroa ÍJ; Vaglio A; Vassilopoulos D; Brembilla G; Kallinikou N; Terrier B
Article: THORAX. 2025;80(6):358-368
Use of inhaled corticosteroids in bronchiectasis: data from the European Bronchiectasis Registry (EMBARC)
Pollock J; Polverino E; Dhar R; Dimakou K; Traversi L; Bossios A; Haworth C; Loebinger MR; De Soyza A; Vendrell M; Burgel PR; Mertsch P; Mcdonnell MJ; Skgrat S; Maiz-Carro L; Sibila O; van der Eerden M; Kauppi P; Hill AT; Wilson R; Milenkovic B; Menendez R; Murris M; Crichton ML; Borecki S; Obradovic D; Irfan M; Eshenkulova V; Nowinski A; Amorim A; Torres A; Lorent N; Welte T; Blasi F; Van Braeckel E; Altenburg J; Shteinberg M; Boersma W; Elborn JS; Aliberti S; Ringshausen FC; Goeminne P; Chalmers JD
Article: CHEST. 2025;167(4):975-992
Aspergillus Serologic Findings and Clinical Outcomes in Patients With Bronchiectasis Data From the European Bronchiectasis Registry
Pollock J; Goeminne PC; Aliberti S; Polverino E; Crichton ML; Ringshausen FC; Dhar R; Vendrell M; Burgel P-R; Haworth CS; De Soyza A; De Gracia J; Bossios A; Rademacher J; Gruenewaldt A; Mcdonnell M; Stolz D; Sibila O; van der Eerden M; Kauppi P; Hill AT; Wilson R; Amorim A; Munteanu O; Menendez R; Torres A; Welte T; Blasi F; Boersma W; Elborn JS; Shteinberg M; Dimakou K; Chalmers JD; Loebinger MR
Journal article: EUROPEAN RESPIRATORY JOURNAL. 2025;65(3):2400691
Patient-centred composite scores as tools for assessment of response to biological therapy for paediatric and adult severe asthma
Khaleva E; Brightling C; Eiwegger T; Altraja A; Bégin P; Blumchen K; Bossios A; Bourdin A; Ten Brinke A; Brusselle G; Bumbacea RS; Bush A; Casale TB; Clarke GW; Chaudhuri R; Chung KF; Coleman C; Corren J; Dahlén S-E; Deschildre A; Djukanovic R; Eger K; Exley A; Fleming L; Fowler SJ; Gaillard EA; Gappa M; Gupta A; Haitchi HM; Hashimoto S; Heaney LG; Hedlin G; Henderson M; Hua W; Jackson DJ; Karadag B; Katelaris CH; Koh MS; Kopp MV; Koppelman GH; Kull I; Kurukulaaratchy RJ; Lee J-H; Mahler V; Mäkelä M; Masoli M; Mathioudakis AG; Mazon A; Melén E; Milger K; Moeller A; Murray CS; Nagakumar P; Nair P; Negus J; Nieto A; Papadopoulos NG; Paton J; Pijnenburg MW; Pike KC; Porsbjerg C; Rattu A; Rupani H; Rusconi F; Rutjes NW; Saglani S; Seddon P; Siddiqui S; Singer F; Tajiri T; Turner S; Upham JW; Vijverberg SJH; Wark PAB; Wechsler ME; Yasinska V; Roberts G
Article: ERJ OPEN RESEARCH. 2025;11(2):1255-2024
ERS Congress 2024: highlights from the Airway Diseases Assembly
Lim CX; Abohalaka R; Wang R; Sykes DL; Ardesi F; Zappa M; Bonini M; Braunstahl G-J; Mathioudakis AG; Snelgrove RJ; Pobeha P; Ananth S; Schleich F; Bossios A; Beech A
Article: EUROPEAN RESPIRATORY JOURNAL. 2025;65(3):2400691
Patient-centred composite scores as tools for assessment of response to biological therapy for paediatric and adult severe asthma
Khaleva E; Brightling C; Eiwegger T; Altraja A; Begin P; Blumchen K; Bossios A; Bourdin A; Ten Brinke A; Brusselle G; Bumbacea RS; Bush A; Casale TB; Clarke GW; Chaudhuri R; Chung KF; Coleman C; Corren J; Dahlen S-E; Deschildre A; Djukanovic R; Eger K; Exley A; Fleming L; Fowler SJ; Gaillard EA; Gappa M; Gupta A; Haitchi HM; Hashimoto S; Heaney LG; Hedlin G; Henderson M; Hua W; Jackson DJ; Karadag B; Katelaris CH; Koh MS; Kopp MV; Koppelman GH; Kull I; Kurukulaaratchy RJ; Lee J-H; Mahler V; Makela M; Masoli M; Mathioudakis AG; Mazon A; Melen E; Milger K; Moeller A; Murray CS; Nagakumar P; Nair P; Negus J; Nieto A; Papadopoulos NG; Paton J; Pijnenburg MW; Pike KC; Porsbjerg C; Rattu A; Rupani H; Rusconi F; Rutjes NW; Saglani S; Seddon P; Siddiqui S; Singer F; Tajiri T; Turner S; Upham JW; Vijverberg SJH; Wark PAB; Wechsler ME; Yasinska V; Roberts G
Article: RESPIROLOGY. 2024;29(11):942-950
Treatable traits and exacerbation risk in patients with uncontrolled asthma prescribed GINA step 1-3 treatment: A nationwide asthma cohort study
Konradsen JR; Selberg S; Odling M; Sundbaum JK; Bossios A; Stridsman C
Article: RESPIRATORY MEDICINE. 2024;231:107714
Adherence to inhaled corticosteroid therapy and treatment escalation in the Swedish adult asthma population
Packham S; Odling M; Bossios A; Konradsen JR; Stridsman C
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2024;210(1):119-127
The Association between Bronchiectasis and Chronic Obstructive Pulmonary Disease Data from the European Bronchiectasis Registry (EMBARC)
Polverino E; De Soyza A; Dimakou K; Traversi L; Bossios A; Crichton ML; Ringshausen FC; Vendrell M; Burgel P-R; Haworth CS; Loebinger MR; Lorent N; Pink I; McDonnell M; Skrgat S; Carro LM; Sibila O; van der Eerden M; Kauppi P; Shoemark A; Amorim A; Brown JS; Hurst JR; Miravitlles M; Menendez R; Torres A; Welte T; Blasi F; Altenburg J; Shteinberg M; Boersma W; Elborn SJ; Goeminne PC; Aliberti S; Chalmers JD
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2024;153(6):1553-1562
Bronchiectasis and asthma: Data from the European Bronchiectasis Registry (EMBARC)
Polverino E; Dimakou K; Traversi L; Bossios A; Haworth CS; Loebinger MR; De Soyza A; Vendrell M; Burgel P-R; Mertsch P; McDonnell M; Skrgat S; Carro LM; Sibila O; van der Eerden M; Kauppi P; Hill AT; Wilson R; Milenkovic B; Menendez R; Murris M; Digalaki T; Crichton ML; Borecki S; Obradovic D; Nowinski A; Amorim A; Torres A; Lorent N; Welte T; Blasi F; Van Braeckel E; Altenburg J; Shoemark A; Shteinberg M; Boersma W; Elborn JS; Aliberti S; Ringshausen FC; Chalmers JD; Goeminne PC
Article: EUROPEAN RESPIRATORY JOURNAL. 2024;63(6):2301689
Airway clearance management in people with bronchiectasis: data from the European Bronchiectasis Registry (EMBARC)
Spinou A; Hererro-Cortina B; Aliberti S; Goeminne PC; Polverino E; Dimakou K; Haworth CS; Loebinger MR; De Soyza A; Vendrell M; Burgel PR; McDonnell M; Sutharsan S; Skrgat S; Maiz-Carro L; Sibila O; Stolz D; Kauppi P; Bossios A; Hill AT; Clifton I; Crichton ML; Walker P; Menendez R; Borecki S; Obradovic D; Nowinski A; Amorim A; Torres A; Lorent N; Welte T; Blasi F; Makek MJ; Shteinberg M; Boersma W; Elborn JS; Chalmers JD; Ringshausen FC
Article: EUROPEAN RESPIRATORY JOURNAL. 2024;63(4):2301554
Objective sputum colour assessment and clinical outcomes in bronchiectasis: data from the European Bronchiectasis Registry (EMBARC)
Aliberti S; Ringshausen FC; Dhar R; Haworth CS; Loebinger MR; Dimakou K; Crichton ML; De Soyza A; Vendrell M; Burgel P-R; Mcdonnell M; Skrgat S; Carro LM; de Roux A; Sibila O; Bossios A; van der Eerden M; Kauppi P; Wilson R; Milenkovic B; Menendez R; Murris M; Borekci S; Munteanu O; Obradovic D; Nowinski A; Amorim A; Torres A; Lorent N; Van Braeckel E; Altenburg J; Shoemark A; Shteinberg M; Boersma W; Goeminne PC; Elborn JS; Hill AT; Welte T; Blasi F; Polverino E; Chalmers JD
Article: ERJ OPEN RESEARCH. 2023;9(6):00590-2023
COVID-19 vaccination acceptance, safety and side-effects in European patients with severe asthma
Bossios A; Bacon AM; Eger K; Paroczai D; Schleich F; Hanon S; Sergejeva S; Zervas E; Katsoulis K; Aggelopoulou C; Kostikas K; Gaki E; Rovina N; Csoma Z; Grisle I; Bieksiene K; Palacionyte J; ten Brinke A; Hashimoto S; Mihaltan F; Nenasheva N; Zvezdin B; Cekerevac I; Hromis S; Cupurdija V; Lazic Z; Chaudhuri R; Smith SJ; Rupani H; Haitchi HM; Kurukulaaratchy R; Fulton O; Frankemolle B; Howarth P; Porsbjerg C; Bel EH; Djukanovic R; Hyland ME
Journal article: ERJ OPEN RESEARCH. 2023;9(6):590-2023
COVID-19 vaccination acceptance, safety and side-effects in European patients with severe asthma.
Bossios A; Bacon AM; Eger K; Paróczai D; Schleich F; Hanon S; Sergejeva S; Zervas E; Katsoulis K; Aggelopoulou C; Kostikas K; Gaki E; Rovina N; Csoma Z; Grisle I; Bieksiené K; Palacionyte J; Ten Brinke A; Hashimoto S; Mihălţan F; Nenasheva N; Zvezdin B; Čekerevac I; Hromiš S; Ćupurdija V; Lazic Z; Chaudhuri R; Smith SJ; Rupani H; Haitchi HM; Kurukulaaratchy R; Fulton O; Frankemölle B; Howarth P; Porsbjerg C; Bel EH; Djukanovic R; Hyland ME
Article: EUROPEAN RESPIRATORY JOURNAL. 2023;62(3):2202474
Severe asthma trajectories in adults: findings from the NORDSTAR cohort
von Bullow A; Hansen S; Sandin P; Ernstsson O; Janson C; Lehtimaeki L; Kankaanranta H; Ulrik C; Aarli BB; Geale K; Tang ST; Wolf M; Backer V; Hilberg O; Altraja A; Backman H; Ludviksdottir D; Bjornsdottir US; Kauppi P; Sandstrom T; Sverrild A; Yasinska V; Kilpelainen M; Dahlen B; Viinanen A; Bjermer L; Bossios A; Porsbjerg C
Article: ERJ OPEN RESEARCH. 2023;9(3):34-2023
ERS International Congress 2022: highlights from the Airway Diseases Assembly
Beech A; Portacci A; Herrero-Cortina B; Mathioudakis AG; Gotera C; Uller L; Ricciardolo FLM; Pobeha P; Snelgrove RJ; Braunstahl G-J; Bossios A; Usmani O; Ananth S
Article: ERJ OPEN RESEARCH. 2023;9(2):687-2022
Prevalence and management of severe asthma in the Nordic countries: findings from the NORDSTAR cohort
Hansen S; von Bulow A; Sandin P; Ernstsson O; Janson C; Lehtimaki L; Kankaanranta H; Ulrik C; Aarli BB; Wahl HF; Geale K; Tang ST; Wolf M; Larsen T; Altraja A; Backman H; Kilpelainen M; Viinanen A; Ludviksdottir D; Kauppi P; Sverrild A; Lehmann S; Backer V; Yasinska V; Skjold T; Karjalainen J; Bossios A; Porsbjerg C
Article: ERJ OPEN RESEARCH. 2022;8(4):273-2022
Heterogeneity in the use of biologics for severe asthma in Europe: a SHARP ERS study
Frix A-N; Heaney LG; Dahlen B; Mihaltan F; Sergejeva S; Popovic-Grle S; Sedlak V; Lehtimaki L; Bourdin A; Korn S; Zervas E; Csoma Z; Ludviksdottir D; Butler M; Canonica GW; Grisle I; Bieksiene K; Ten Brinke A; Kuna P; Loureiro CC; Nenasheva NM; Lazic Z; Skrgat S; Ramos-Barbon D; Leuppi J; Gemicioglu B; Bossios A; Porsbjerg CM; Bel EH; Djukanovic R; Louis R
Article: BIOMEDICINES. 2022;10(8):2011
Biomarkers of Clot Activation and Degradation and Risk of Future Major Cardiovascular Events in Acute Exacerbation of COPD: A Cohort Sub-Study in a Randomized Trial Population
Kamstrup P; Sand JMB; Ulrik CS; Janner J; Ronn CP; Ronnow SR; Leeming DJ; Jensen SG; Wilcke T; Mathioudakis AG; Miravitlles M; Lapperre T; Bendstrup E; Frikke-Schmidt R; Murray DD; Itenov T; Bossios A; Nielsen SD; Vestbo J; Biering-Sorensen T; Karsdal M; Jensen J-U; Sivapalan P
Article: ERJ OPEN RESEARCH. 2022;8(2):65-2022
The effect of the COVID-19 pandemic on severe asthma care in Europe: will care change for good?
Eger K; Paroczai D; Bacon A; Schleich F; Sergejeva S; Bourdin A; Vachier I; Zervas E; Katsoulis K; Papapetrou D; Kostikas K; Csoma Z; Heffler E; Canonica GW; Grisle I; Bieksiene K; Palacionyte J; Ten Brinke A; Hashimoto S; Smeenk FWJM; Braunstahl G-J; van der Sar S; Mihaltan F; Nenasheva N; Peredelskaya M; Zvezdin B; Cekerevac I; Hromis S; Cupurdija V; Lazic Z; Milenkovic B; Dimic-Janjic S; Yasinska V; Dahlen B; Bossios A; Lazarinis N; Aronsson D; Egesten A; Munir AKM; Ahlbeck L; Janson C; Skrgat S; Edelbaher N; Leuppi J; Jaun F; Rudiger J; Pavlov N; Gianella P; Fischer R; Charbonnier F; Chaudhuri R; Smith SJ; Doe S; Fawdon M; Masoli M; Heaney L; Haitchi HM; Kurukulaaratchy R; Fulton O; Frankemolle B; Gibson T; Needham K; Howarth P; Djukanovic R; Bel E; Hyland M
Article: ERJ OPEN RESEARCH. 2021;7(4):399-2021
ROSE: radiology, obstruction, symptoms and exposure - a Delphi consensus definition of the association of COPD and bronchiectasis by the EMBARC Airways Working Group
Traversi L; Miravitlles M; Martinez-Garcia MA; Shteinberg M; Bossios A; Dimakou K; Jacob J; Hurst JR; Paggiaro PL; Ferri S; Hillas G; Vogel-Claussen J; Dettmer S; Aliberti S; Chalmers JD; Polverino E
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2021;148(2):407-419
Lung function fluctuation patterns unveil asthma and COPD phenotypes unrelated to type 2 inflammation
Delgado-Eckert E; James A; Meier-Girard D; Kupczyk M; Andersson LI; Bossios A; Mikus M; Ono J; Izuhara K; Middelveld R; Dahlen B; Gaga M; Siafakas NM; Papi A; Beghe B; Joos G; Rabe KF; Sterk PJ; Bel EH; Johnston SL; Chanez P; Gjomarkaj M; Howarth PH; Nizankowska-Mogilnicka E; Dahlen S-E; Frey U
Article: FRONTIERS IN IMMUNOLOGY. 2021;12:677550
Adiponectin/AdipoR1 Axis Promotes IL-10 Release by Human Regulatory T Cells
Ramos-Ramirez P; Malmhall C; Tliba O; Radinger M; Bossios A
Article: ALLERGY. 2021;76(1):71-89
Biologicals in atopic disease in pregnancy: An EAACI position paper
Pfaller B; Yepes-Nunez JJ; Agache I; Akdis CA; Alsalamah M; Bavbek S; Bossios A; Boyman O; Chaker A; Chan S; Chatzipetrou A; du Toit G; Jutel M; Kauppi P; Kolios A; Li C; Matucci A; Marson A; Bendien S; Palomares O; Rogala B; Szepfalusi Z; Untersmayr E; Vultaggio A; Eiwegger T
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2020;21(23):E8990-8990
Lung Regulatory T Cells Express Adiponectin Receptor 1: Modulation by Obesity and Airway Allergic Inflammation
Ramos-Ramirez P; Malmhall C; Johansson K; Adner M; Lotvall J; Bossios A
Article: ALLERGY. 2020;75(11):2764-2774
Considerations on biologicals for patients with allergic disease in times of the COVID-19 pandemic: An EAACI statement
Vultaggio A; Agache I; Akdis CA; Akdis M; Bavbek S; Bossios A; Bousquet J; Boyman O; Chaker AM; Chan S; Chatzipetrou A; Feleszko W; Firinu D; Jutel M; Kauppi P; Klimek L; Kolios A; Kothari A; Kowalski ML; Matucci A; Palomares O; Pfaar O; Rogala B; Untersmayr E; Eiwegger T
Article: ALLERGOLOGIE. 2020;43(7):255-271
Use of biologicals in allergic and type 2 inflammatory diseases in the current COVID 19 pandemic
Klimek L; Pfaar O; Worm M; Eiwegger T; Hagemann J; Ollert M; Untersmayr E; Hoffmann-Sommergruber K; Vultaggio A; Agache I; Bavbek S; Bossios A; Casper I; Chan S; Chatzipetrou A; Vogelberg C; Firinu D; Kauppi P; Kolios A; Kothari A; Matucci A; Palomares O; Szepfalusi Z; Pohl W; Hoetzenecker W; Rosenkranz A; Bergmann K-C; Bieber T; Buhl R; Buters J; Darsow U; Keil T; Kleine-Tebbe J; Lau S; Maurer M; Merk H; Moesges R; Saloga J; Staubach P; Jappe U; Rabe C; Rabe U; Vogelmeier C; Biedermann T; Jung K; Schlenter W; Ring J; Chaker A; Wehrmann W; Becker S; Freudelsperger L; Muelleneisen N; Nemat K; Czech W; Wrede H; Brehler R; Fuchs T; Tomazic P-V; Aberer W; Fink-Wagner A; Horak F; Woehrl S; Niederberger-Leppin V; Pali-Schoell I; Roller-Wirnsberger R; Spranger O; Valenta R; Akdis M; Matricardi PM; Spertini F; Khaltaev N; Michel J-P; Nicod L; Schmid-Grendelmeier P; Idzko M; Hamelmann E; Jakob T; Werfel T; Wagenmann M; Taube C; Jensen-Jarolim E; Korn S; Hentges F; Schwarze J; OMahony L; Knol E; del Giacco S; Chivato Perez T; Bousquet J; Zuberbier T; Akdis C; Jutel M
Journal article: ALLERGO JOURNAL. 2020;29(4):14-27
Use of biologics in allergic and type 2 inflammatory diseases in the current Covid 19 pandemic^{a, b, c}
Klimek L; Pfaar O; Worm M; Eiwegger T; Hagemann J; Ollert M; Untersmayr E; Hoffmann-Sommergruber K; Vultaggio A; Agache I; Bavbek S; Bossios A; Casper I; Chan S; Chatzipetrou A; Vogelberg C; Firinu D; Kauppi P; Kolios A; Kothari A; Matucci A; Palomares O; Szepfalusi Z; Pohl W; Hoetzenecker W; Rosenkranz AR; Bergmann K-C; Bieber T; Buhl R; Buters J; Darsow U; Keil T; Kleine-Tebbe J; Lau S; Maurer M; Merk H; Moesges R; Saloga J; Staubach P; Jappe U; Rabe KF; Rabe U; Vogelmeier C; Biedermann T; Jung K; Schlenter W; Ringa J; Chaker A; Wehrmann W; Becker S; Freudelsperger L; Muelleneisen N; Nemat K; Czech W; Wrede H; Brehler R; Fuchs T; Tomazic P-V; Aberer W; Fink-Wagner A-H; Horak F; Woehrl S; Niederberger-Leppin V; Pali-Schoell I; Pohlg W; Roller-Wirnsberger R; Spranger O; Valenta R; Akdis M; Matricardi PM; Spertini F; Khaltaev N; Michel J-P; Nicod L; Schmid-Grendelmeier P; Idzko M; Hamelmann E; Jakob T; Werfel T; Wagenmann M; Taube C; Jensen-Jarolim E; Korn S; Hentges F; Schwarze J; O'Mahony L; Knol EF; del Giacco S; Chivato Perez T; Bousquet J; Zuberbier T; Akdis C; Jutel M
Article: ALLERGOL SELECT. 2020;4:53-68
Use of biologicals in allergic and type-2 inflammatory diseases during the current COVID-19 pandemic: Position paper of Ärzteverband Deutscher Allergologen (AeDA)A, Deutsche Gesellschaft für Allergologie und Klinische Immunologie (DGAKI)B, Gesellschaft für Pädiatrische Allergologie und Umweltmedizin (GPA)C, Österreichische Gesellschaft für Allergologie und Immunologie (ÖGAI)D, Luxemburgische Gesellschaft für Allergologie und Immunologie (LGAI)E, Österreichische Gesellschaft für Pneumologie (ÖGP)F in co-operation with the German, Austrian, and Swiss ARIA groupsG, and the European Academy of Allergy and Clinical Immunology (EAACI)H.
Klimek L; Pfaar O; Worm M; Eiwegger T; Hagemann J; Ollert M; Untersmayr E; Hoffmann-Sommergruber K; Vultaggio A; Agache I; Bavbek S; Bossios A; Casper I; Chan S; Chatzipetrou A; Vogelberg C; Firinu D; Kauppi P; Kolios A; Kothari A; Matucci A; Palomares O; Szépfalusi Z; Pohl W; Hötzenecker W; Rosenkranz AR; Bergmann K-C; Bieber T; Buhl R; Buters J; Darsow U; Keil T; Kleine-Tebbe J; Lau S; Maurer M; Merk H; Mösges R; Saloga J; Staubach P; Jappe U; Rabe KF; Rabe U; Vogelmeier C; Biedermann T; Jung K; Schlenter W; Ring J; Chaker A; Wehrmann W; Becker S; Freudelsperger L; Mülleneisen N; Nemat K; Czech W; Wrede H; Brehler R; Fuchs T; Tomazic P-V; Aberer W; Fink-Wagner A-H; Horak F; Wöhrl S; Niederberger-Leppin V; Pali-Schöll I; Pohl W; Roller-Wirnsberger R; Spranger O; Valenta R; Akdis M; Matricardi PM; Spertini F; Khaltaev N; Michel J-P; Nicod L; Schmid-Grendelmeier P; Idzko M; Hamelmann E; Jakob T; Werfel T; Wagenmann M; Taube C; Jensen-Jarolim E; Korn S; Hentges F; Schwarze J; O Mahony L; Knol EF; Del Giacco S; Chivato Pérez T; Bousquet J; Bedbrook A; Zuberbier T; Akdis C; Jutel M
Article: EUROPEAN RESPIRATORY JOURNAL. 2020;55(1):1901163
Characteristics and treatment regimens across ERS SHARP severe asthma registries
van Bragt JJMH; Adcock IM; Bel EHD; Braunstahl G-J; ten Brinke A; Busby J; Canonica GW; Cao H; Chung KF; Csoma Z; Dahlen B; Davin E; Hansen S; Heffler E; Horvath I; Korn S; Kots M; Kuna P; Kwon N; Louis R; Plaza V; Porsbjerg C; Ramos-Barbon D; Richards LB; Skrgat S; Sont JK; Vijverberg SJH; Weersink EJM; Yasinska V; Wagers SS; Djukanovic R; Maitland-van der Zee AH; Abenhardt B; Adcock IM; Adler J; Alfonso R; Ali R; Alkameh S; Almonacid Sanchez C; Alvares L; Anderson G; Assing K; Ayre S; Becker J; Bel EHD; Bergmann K; Bieksiene K; Bjerring N; Blasi F; Bloemen P; Blum H; Boeing S; Bonavia M; Bossios A; Bourdin A; Braunstahl G-J; Brons A; Brusselle G; Buis J; Busby J; Caiaffa M; Calabrese C; Camiciottoli G; Canonica GW; Cao H; Caruso C; Castilla Martinez M; Centanni S; Chung KF; Cisneros Serrano C; Corsico A; Cosmi L; Costantino M; Costello R; Crimi N; Csoma Z; Dahlen S; Dahlen B; D'Amato M; Davies D; Davin E; Garcia-Cosio Piqueras FDB; Decarlo G; Deimling A; Del Giacco S; Diaz Campos R; Djandji M; Djukanovic R; Doberer D; Dupont L; Dyett K; Edelbaher N; Edelmann M; Ehmann R; Ekberg-Jansson A; Farsi A; Favero E; Feimer J; Fletcher M; Foschino B; Frankemolle B; Gaga M; Gappa M; Garcia de Pedro J; Garcia Rivero J; Gasplmayr M; Gebhardt R; Geldmacher H; Geltner C; Gerstlauer M; Gibson T; Giuseppe G; Gogoll C; Grimm-Sachs V; Grisle I; Gruen B; Gruenewaldt A; Guarnieri G; Gullon Blanco J; Hamelmann E; Hamerlijnck D; Hammers-Reinhard A; Hanon S; Hansen S; Harzheim D; Heaney L; Heffler E; Hellmich S; Herden M; Hering T; Herth F; Hilberg O; Horvath I; Howarth P; Hubatsch M; Humbert M; Husemann K; Idzko M; Jackson D; Jandl M; Jaumont X; Joos G; Joest M; Juech M; Kabesch M; Kaiser-Labusch P; Kardos P; Kaessner F; Keeley T; Kerr W; Kirschner J; Klimek L; Koca M; Koczulla R; Koerner-Rettberg C; Kopac P; Korn S; Kots M; Kronsbein J; Kuna P; Lipinska IK; Kwon N; Langer M; Langeveld B; Lantz A; Lazarinis N; Lazic Z; Lehtimaki L; Leuppi J; Lombardi C; Lommatzsch M; Lopez-Vina A; Louis R; Luca R; Ludviksdottir D; Luettecke-Hecht C; Macchia L; Magni T; Maitland-van der Zee AH; Martinez Rivera C; Mastoridis P; Mazza F; Menzella F; Menzies-Gow A; Michils A; Mihaltan F; Milanese M; Milger-Kneidinger K; Molinska J; Montagna I; Montuschi P; Muelleneisen N; Munoz Esquerre M; Nanzer-Kelly A; Nenasheva N; Neurohr C; Nucera E; Otker J; Oud K; Paggiaro P; Parente R; Parkinson J; Passalacqua G; Patberg N; Patella V; Patino O; Paulsson T; Peche R; Pelaia G; Peress E; Perez de Llano L; Pfeffer P; Pfister P; Pilette C; Pinedo Sierra C; Pini L; Plaza V; Porsbjerg C; Powitz F; Ramos-Barbon D; Ranger T; Rasmussen L; Rasmussen K; Rezelj M; Ricciardi L; Ricciardolo F; Richards LB; Ridolo E; Rijssenbeek-Nouwens L; Rolla G; Romero Ribate D; Ruediger S; Safioti G; Sandstrom T; Santus P; Sauer R; Schauerte G; Schipmann R; Schleich F; Schmid J; Schmidt F; Schmidt O; Schmitz M; Schrag T; Schroeer S; Schultz K; Schulz C; Scichilone N; Sedlak V; Selb J; Senna G; Sergejeva S; Serrano Pariente J; Sichau M; Simona D; Singer A; Skowasch D; Skrgat S; Smeenk F; Smith S; Solidoro P; Sont JK; Spadaro G; Spanevello A; Stefansdottir M; Steinmetz K; Steiss J; Stephan M; Stieglitz S; Suhling H; Taube C; ten Brinke A; Yavuz ST; Tudoric N; Ulrik C; van Bragt JJMH; van de Ven M; van den Elshout F; Van Dyke M; Van Nederveen-Bendien S; van Veen I; Vandenplas O; Velthove K; Vianello A; Vijverberg SJH; Vogelberg C; Wagers SS; Wallen-Nielsen E; Weersink EJ; Wisskirchen T; Yacoub M; Yancey S; Yasinska V; Zappa M; Zielen S; Zimmermann C; Zimmermann R
Article: ERJ OPEN RESEARCH. 2019;5(1):225-2018
Research highlights from the 2018 European Respiratory Society International Congress: airway disease
Schleich F; Bikov A; Mathioudakis AG; McDonnell M; Andersson C; Bonini M; Uller L; Idzko M; Singh D; Luis Lopez-Campos J; Bossios A; Adcock IM; Usmani O; Spanevello A; Bonvini SJ
Article: JOURNAL OF ASTHMA. 2018;55(8):844-850
Excessive daytime sleepiness in asthma: What are the risk factors?
Kallin SA; Lindberg E; Sommar JN; Bossios A; Ekerljung L; Malinovschi A; Middelveld R; Janson C
Article: FRONTIERS IN IMMUNOLOGY. 2018;9:1677
Smoking Is Associated With Low Levels of Soluble PD-L1 in Rheumatoid Arthritis
Wasen C; Erlandsson MC; Bossios A; Ekerljung L; Malmhall C; Silfversward ST; Pullerits R; Lundback B; Bokarewa MI
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2018;141(6):2256-2264.e2
High prevalence of severe asthma in a large random population study
Mincheva R; Ekerljung L; Bossios A; Lundback B; Lotvall J
Article: JOURNAL OF AUTOIMMUNITY. 2017;78:101-110
Smoking activates cytotoxic CD8⁺ T cells and causes survivin release in rheumatoid arthritis
Wasen C; Turkkila M; Bossios A; Erlandsson M; Andersson KM; Ekerljung L; Malmhall C; Brisslert M; Silfversward ST; Lundback B; Bokarewa MI
Article: BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE. 2017;1863(3):663-673
Survivin controls biogenesis of microRNA in smokers: A link to pathogenesis of rheumatoid arthritis
Andersson KME; Turkkila M; Erlandsson MC; Bossios A; Silfversward ST; Hu D; Ekerljung L; Malmhall C; Weiner HL; Lundback B; Bokarewa MI
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2016;11:2245-2258
Interleukin-16-producing NK cells and T-cells in the blood of tobacco smokers with and without COPD
Andersson A; Malmhall C; Houltz B; Tengvall S; Sjostrand M; Qvarfordt I; Linden A; Bossios A
Article: PLOS ONE. 2016;11(8):e0161161
Precursor B Cells Increase in the Lung during Airway Allergic Inflammation: A Role for B Cell-Activating Factor
Samitas K; Malmhall C; Radinger M; Ramos-Ramirez P; Lu Y; Deak T; Semitekolou M; Gaga M; Sjostrand M; Lotvall J; Bossios A
Article: ERJ OPEN RESEARCH. 2016;2(3):51-2015
Only severe COPD is associated with being underweight: results from a population survey.
Eriksson B; Backman H; Bossios A; Bjerg A; Hedman L; Lindberg A; Rönmark E; Lundbäck B
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2016;83(4):244-254
Weight Gain Alters Adiponectin Receptor 1 Expression on Adipose Tissue-Resident Helios plus Regulatory T Cells
Ramos-Ramirez P; Malmhall C; Johansson K; Lotvall J; Bossios A
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2015;45(1):211-219
Aspirin-intolerant asthma in the population: prevalence and important determinants
Eriksson J; Ekerljung L; Bossios A; Bjerg A; Wennergren G; Ronmark E; Toren K; Lotvall J; Lundback B
Article: RESPIRATORY MEDICINE. 2014;108(5):685-693
Five-fold increase in use of inhaled corticosteroids over 18 years in the general adult population in West Sweden
Ekerljung L; Bjerg A; Bossios A; Axelsson M; Toren K; Wennergren G; Lotvall J; Lundback B
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2014;133(5):1429-1438.e7
MicroRNA-155 is essential for TH2-mediated allergen-induced eosinophilic inflammation in the lung
Malmhall C; Alawieh S; Sjostrand M; Bossios A; Eldh M; Radinger M
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2014;44(2):250-260
The association of asthma, nasal allergies, and positive skin prick tests with obesity, leptin, and adiponectin
Newson RB; Jones M; Forsberg B; Janson C; Bossios A; Dahlen S-E; Toskala EM; Al-Kalemji A; Kowalski ML; Rymarczyk B; Salagean EM; van Drunen CM; Bachert C; Wehrend T; Kraemer U; Mota-Pinto A; Burney P; Leynaert B; Jarvis D
Article: METHODS IN MOLECULAR BIOLOGY. 2014;1178:29-43
CD34+ eosinophil-lineage-committed cells in the mouse lung.
Bossios A; Rådinger M
Journal article: CLINICAL AND TRANSLATIONAL ALLERGY. 2013;3(Suppl 1):p6
Multi‐symptom asthma as an indication of disease severity in epidemiology
Ekerljung L; Bossios A; Lötvall J; Olin A; Rönmark E; Wennergren G; Torén K; Lundbäck B
Journal article: CLINICAL AND TRANSLATIONAL ALLERGY. 2013;3(Suppl 1):p7
Circulating eosinophil progenitors express major trafficking related molecules and are more activated compared to mature eosinophils in patients with asthma
Lu Y; Malmhäll C; Sjöstrand M; Rådinger M; Lundbäck B; Lötvall J; Bossios A
Journal article: CLINICAL AND TRANSLATIONAL ALLERGY. 2013;3(Suppl 1):o2
Toll‐like receptor expression in severe asthma with chronic rhinosinusitis
Malmhäll C; Bossios A; Sjöstrand M; Lundbäck B; Lötvall J; Rådinger M
Article: PLOS ONE. 2012;7(6):e40012
Immunophenotyping of Circulating T Helper Cells Argues for Multiple Functions and Plasticity of T Cells In Vivo in Humans - Possible Role in Asthma
Malmhall C; Bossios A; Radinger M; Sjostrand M; Lu Y; Lundback B; Lotvall J
Article: JOURNAL OF EXTRACELLULAR VESICLES. 2012;1(1)
Characterization of mRNA and microRNA in human mast cell-derived exosomes and their transfer to other mast cells and blood CD34 progenitor cells
Ekstroem K; Valadi H; Sjoestrand M; Malmhaell C; Bossios A; Eldh M; Loetvall J
Article: EUROPEAN RESPIRATORY JOURNAL. 2011;38(4):825-832
Multi-symptom asthma as an indication of disease severity in epidemiology
Ekerljung L; Bossios A; Lotvall J; Olin A-C; Ronmark E; Wennergren G; Toren K; Lundback B
Article: CLINICAL AND TRANSLATIONAL ALLERGY. 2011;1(1):6
Effect of simulated gastro-duodenal digestion on the allergenic reactivity of beta-lactoglobulin.
Bossios A; Theodoropoulou M; Mondoulet L; Rigby NM; Papadopoulos NG; Bernard H; Adel-Patient K; Wal J-M; Mills CE; Papageorgiou P
Article: PLOS ONE. 2011;6(5):e19889
Expansion of CD4⁺CD25⁺ and CD25^- T-Bet, GATA-3, Foxp3 and RORγt Cells in Allergic Inflammation, Local Lung Distribution and Chemokine Gene Expression
Lu Y; Malmhall C; Sjostrand M; Radinger M; O'Neil SE; Lotvall J; Bossios A
Article: EUROPEAN RESPIRATORY JOURNAL. 2011;37(2):331-341
Osteopontin expression and relation to disease severity in human asthma
Samitas K; Zervas E; Vittorakis S; Semitekolou M; Alissafi T; Bossios A; Gogos H; Economidou E; Lotvall J; Xanthou G; Panoutsakopoulou V; Gaga M
Article: JOURNAL OF TRANSLATIONAL MEDICINE. 2011;9:9
Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages
Lasser C; Alikhani VS; Ekstrom K; Eldh M; Paredes PT; Bossios A; Sjostrand M; Gabrielsson S; Lotvall J; Valadi H
Article: IMMUNOLOGY. 2011;132(1):144-154
Local proliferation and mobilization of CCR3⁺ CD34⁺ eosinophil-lineage-committed cells in the lung
Radinger M; Bossios A; Sjostrand M; Lu Y; Malmhall C; Dahlborn A-K; Lee JJ; Lotvall J
Article: AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY. 2011;300(1):L43-L55
Effects of tobacco smoke on IL-16 in CD8⁺ cells from human airways and blood: a key role for oxygen free radicals?
Andersson A; Bossios A; Malmhall C; Sjostrand M; Eldh M; Eldh B-M; Glader P; Andersson B; Qvarfordt I; Riise GC; Linden A
Article: ALLERGY ASTHMA AND CLINICAL IMMUNOLOGY. 2010;6(1):28
Quantitative expression of osteopontin in nasal mucosa of patients with allergic rhinitis: effects of pollen exposure and nasal glucocorticoid treatment.
O'Neil SE; Malmhäll C; Samitas K; Pullerits T; Bossios A; Lötvall J
Article: ALLERGY. 2010;65(7):831-839
IL-5 expression and release from human CD34 cells in vitro; ex vivo evidence from cases of asthma and Churg-Strauss syndrome
Bossios A; Sjostrand M; Dahlborn A-K; Samitas K; Malmhall C; Gaga M; Lotvall J
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2010;71(3):176-185
New Production of Eosinophils and the Corresponding Th1/Th2 Balance in the Lungs after Allergen Exposure in BALB/c and C57BL/6 Mice
Lu Y; Sjostrand M; Malmhall C; Radinger M; Jeurink P; Lotvall J; Bossios A
Article: PULMONARY PHARMACOLOGY & THERAPEUTICS. 2009;22(3):199-207
IL-17-producing T lymphocytes in lung tissue and in the bronchoalveolar space after exposure to endotoxin from Escherichia coli in vivo - effects of anti-inflammatory pharmacotherapy
Prause O; Bossios A; Silverpil E; Ivanov S; Bozinovski S; Vlahos R; Sjostrand M; Anderson GP; Linden A
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2008;38(10):1615-1626
Rhinovirus infection and house dust mite exposure synergize in inducing bronchial epithelial cell interleukin-8 release
Bossios A; Gourgiotis D; Skevaki CL; Saxoni-Papageorgiou P; Lotvall J; Psarras S; Karpathios T; Constandopoulos AG; Johnston SL; Papadopoulos NG
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2008;67(5):480-488
Prolonged eosinophil production after allergen exposure in IFN-γR KO mice is IL-5 dependent
Zhao L-L; Lotvall J; Linden A; Tomaki M; Sjostrand M; Bossios A
Article: VASCULAR AND ENDOVASCULAR SURGERY. 2008;42(1):47-53
A Global Assessment of the Inflammatory Response Elicited Upon Open Abdominal Aortic Aneurysm Repair
Vasdelds SN; Argentou M; Kakisis JD; Bossios A; Gourgiotis D; Karanikolas M; Karatzas G
Article: ALLERGY. 2007;62(12):1410-1418
Regulation of allergen-induced bone marrow eosinophilopoiesis:: role of CD4⁺ and CD8⁺ T cells
Radinger M; Bossios A; Alm A-S; Jeurink P; Lu Y; Malmhall C; Sjostrand M; Lotvall J
Journal article: WORLD ALLERGY ORGANIZATION JOURNAL. 2007;&NA;(&NA;):s301-s302
Exosomes in human blood plasma contain RNA - a genetic signal between cells at a distance?
Alikhani VS; Valadi H; Ekström K; Bossios A; Sjöstrand M; Lötvall J
Article: ALLERGY. 2007;62(9):1007-1013
Effects of pollen and nasal glucocorticoid on FOXP3⁺, GATA-3⁺ and T-bet⁺ cells in allergic rhinitis
Malmhall C; Bossios A; Pullerits T; Lotvall J
Article: NATURE CELL BIOLOGY. 2007;9(6):654-659
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
Valadi H; Ekstrom K; Bossios A; Sjostrand M; Lee JJ; Lotvall JO
Article: AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. 2007;36(4):442-451
Functional relevance of the IL-23-IL-17 axis in lungs in vivo
Ivanov S; Bozinovski S; Bossios A; Valadi H; Vlahos R; Malmhall C; Sjostrand M; Kolls JK; Anderson GP; Linden A
Journal article: BREATHE. 2006;3(1):50-58
Viruses and asthma exacerbations
Bossios A; Papadopoulos NG
Article: RESPIRATORY RESEARCH. 2006;7(1):83
Regulatory role of CD8⁺ T lymphocytes in bone marrow eosinophilopoiesis
Radinger M; Sergejeva S; Johansson A-K; Malmhall C; Bossios A; Sjostrand M; Lee JJ; Lotvall J
Article: PEDIATRIC DIABETES. 2006;7(1):51-59
Oxidative stress and adhesion molecules in children with type 1 diabetes mellitus: a possible link
Mylona-Karayanni C; Gourgiotis D; Bossios A; Kamper EF
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2006;117(2):291-297
Vascular endothelial growth factor-mediated induction of angiogenesis by human rhinoviruses
Psarras S; Volonaki E; Skevaki CL; Xatzipsalti M; Bossios A; Pratsinis H; Tsigkos S; Gourgiotis D; Constantopoulos AG; Papapetropoulos A; Saxoni-Papageorgiou P; Papadopoulos NG
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2005;172(8):1037-1040
Rhinovirus viremia in children with respiratory infections
Xatzipsaiti M; Kyrana S; Tsolia M; Psarras S; Bossios A; Laza-Stanca V; Johnston SL; Papadopoulos NG
Article: RESPIRATORY RESEARCH. 2005;6(1):114
Rhinovirus infection induces cytotoxicity and delays wound healing in bronchial epithelial cells - art. no. 114
Bossios A; Psarras S; Gourgiotis D; Skevaki CL; Constantopoulos AG; Saxoni-Papageorgiou P; Papadopoulos NG
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2005;116(2):299-304
Duration of postviral airway hyperresponsiveness in children with asthma: Effect of atopy
Xepapadaki P; Papadopoulos NG; Bossios A; Manoussakis E; Manousakas T; Saxoni-Papageorgiou P
Article: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2005;84(7):632-638
Interleukin-6 in preterm premature rupture of membranes as an indicator of neonatal outcome
Hatzidaki E; Gourgiotis D; Manoura A; Korakaki E; Bossios A; Galanakis E; Giannakopoulou C
Article: RESPIRATORY RESEARCH. 2005;6(1):33
Airway allergen exposure stimulates bone marrow eosinophilia partly via IL-9 - art. no. 33
Sitkauskiene B; Rådinger M; Bossios A; Johansson AK; Sakalauskas R; Lötvall J
Article: RESPIRATORY MEDICINE. 2004;98(9):879-882
Does respiratory syncytial virus subtype influences the severity of acute bronchiolitis in hospitalized infants?
Papadopoulos NG; Gourgiotis D; Javadyan A; Bossios A; Kallergi K; Psarras S; Tsolia MN; Kafetzis D
Article: EUROPEAN JOURNAL OF PEDIATRICS. 2004;163(8):462-466
Severe hypertriglyceridaemia in a Greek infant: a clinical, biochemical and genetic study
Kavazarakis E; Stabouli S; Gourgiotis D; Roumeliotou K; Traeger-Synodinos J; Bossios A; Fretzayas A; Kanavakis E
Article: JOURNAL OF CLINICAL VIROLOGY. 2004;30(3):267-270
Human metapneumovirus as a causative agent of acute bronchiolitis in infants
Xepapadaki P; Psarras S; Bossios A; Tsolia M; Gourgiotis D; Liapi-Adamidou G; Constantopoulos AG; Kafetzis D; Papadopoulos NG
Article: INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY. 2004;134(3):223-226
Expression of costimulatory molecules in peripheral blood mononuclear cells of atopic asthmatic children during virus-induced asthma exacerbations
Bossios A; Xatzipsalti M; Manoussakis E; Psarros F; Saxoni-Papageorgiou P; Papadopoulos NG
Article: JOURNAL OF ASTHMA. 2004;41(3):285-287
Immune modulator pidotimod decreases the in vitro expression of CD30 in peripheral blood mononuclear cells of atopic asthmatic and normal children
Gourgiotis D; Papadopoulos NG; Bossios A; Zamanis P; Saxoni-Papageorgiou P
Journal article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2003;111(2):s303
Decrease of ex vivo expression of costimulation molecules during virus-induced asthma exacerbations in peripheral blood mononuclear cells of atopic asthmatic children
Bossios A; Papadopoulos NG; Xatzipsalti M; Manousakis E; Psarros F; Gourgiotis D; Constantopoulos A; Saxoni-Papageorgiou P
Article: PEDIATRIC RESEARCH. 2002;52(3):454-458
The impact of serum lipid levels on circulating soluble adhesion molecules in childhood
Kavazarakis E; Moustaki M; Gourgiotis D; Zeis PM; Bossios A; Mavri A; Chronopoulou A; Karpathios T
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2002;165(9):1285-1289
Association of rhinovirus infection with increased disease severity in acute bronchiolitis
Papadopoulos NG; Moustaki M; Tsolia M; Bossios A; Astra E; Prezerakou A; Gourgiotis D; Kafetzis D
Article: CLINICAL INFECTIOUS DISEASES. 2001;33(6):e54-e56
Circulating cytokines in patients with cat scratch disease
Papadopoulos NG; Gourgiotis D; Bossios A; Fretzayas A; Moustaki M; Karpathios T
Article: METABOLISM-CLINICAL AND EXPERIMENTAL. 2001;50(9):1091-1094
Relation of serum leptin levels to lipid profile in healthy children
Kavazarakis E; Moustaki M; Gourgiotis D; Drakatos A; Bossios A; Zeis PM; Xatzidimoula A; Karpathios T
Article: SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES. 2001;33(8):599-603
Unsuspected extra lymphocutaneous dissemination in febrile cat scratch disease
Fretzayas A; Papadopoulos NG; Moustaki M; Bossios A; Koukoutsakis P; Karpathios T
Article: PEDIATRICS. 2000;105(2):E28
Polymorphonuclear elastase as a diagnostic marker of acute pyelonephritis in children
Fretzayas A; Moustaki M; Gourgiotis D; Bossios A; Koukoutsakis P; Stavrinadis C
Article: INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY. 1999;119(1):64-68
Correlation of lymphocyte proliferating cell nuclear antigen expression with dietary cow's milk antigen load in infants with allergy to cow's milk
Papadopoulos NG; Syrigou EI; Bossios A; Manou O; Gourgiotis D; Saxoni-Papageorgiou P
Article: PEDIATRIC ALLERGY AND IMMUNOLOGY. 1998;9(3):125-129
Interferon-gamma pretreatment of peripheral blood mononuclear cells partially restores defective cytokine production in children with atopic dermatitis
Papadopoulos NG; Bossios A; Syrigou EI; Gourgiotis D; Saxoni-Papageorgiou P
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Review: ALLERGY. 2025
Predictors of Response to Biologics for Severe Asthma: A Systematic Review and Meta-Analysis
Rattu A; Dixey P; Charles D; Brightling C; Chung KF; Bossios A; Bourdin A; Djukanovic R; Dahlen S-E; Fleming L; Chaudhuri R; Melen E; Deschildre A; Pilette C; Koppelman GH; Exley A; Anckers F; Miller S; Nielsen H; Williams C; Khaleva E; Roberts G
Editorial comment: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE. 2025;13(9):2529-2531.e1
Comparing allergic rhinitis treatments based on patient satisfaction: A MASK-air® study.
Vieira RJ; Sousa-Pinto B; Gil-Mata S; Bedbrook A; Brussino L; Maria Giuliano AF; Klimek L; Kvedariene V; Niedoszytko M; Pfaar O; Pham-Thi N; Samolinski B; Ventura MT; Zuberbier T; Fonseca JA; Bousquet J; MASK-air Think Tank
Review: EXPERT REVIEW OF RESPIRATORY MEDICINE. 2025;19(8):789-810
Sex steroid hormones and asthma in males: a state-of-the-art review
Ermis SSO; Ercan S; Malmhall C; Adesoba H; Salisu M; Bossios A; Radinger M; Kankaanranta H; Nwaru BI
Letter: ALLERGY. 2025
Alert Card for Patients on Biologicals and Immunosuppressives: An EAACI Position Paper
Chaker A; Kauppi P; Bavbek S; Bossios A; Chatzipetrou A; Firinu D; Rogala B; Matucci A; Vultaggio A; Panzner P; Feleszko W; Eliashar R; Agache I; Klimek L; Torres M; Pfaar O; Palomares O; Shamji M; Eiwegger T; Kolios AGA
Editorial comment: ACTA PAEDIATRICA. 2025;114(7):1731-1733
Clinical Implications of the New Criteria for a Positive Bronchodilator Response in Children With Asthma
Stridsman C; Backman H; Vanfleteren LEGW; Asarnoj A; Ljungberg H; Lindberg A; Bossios A; Konradsen JR
Letter: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE. 2025;13(7):1859-1862.e3
Newly diagnosed eosinophilic granulomatosis with polyangiitis in patients on biologics for severe asthma: A multicenter case series
Rupani H; Bansal AT; Sergejeva S; Nanzer A; Caminati M; Kopac P; Csoma Z; Skrgat S; Milenkovic B; Bieksiene K; Zervas E; Weersink E; Kuna P; Yasinska V; Sedlak V; Dennison P; Rink S; van Nederveen-Bendien S; ten Brinke A; Popovic-Grle S; Bossios A; Samitas K; Anderson GP; Schleich F; Porsbjerg C
Review: FRONTIERS IN IMMUNOLOGY. 2025;16:1598257
The role of T-helper and T regulatory cells in driving neutrophilic and eosinophilic inflammation in bronchiectasis
Fouka E; Linden A; Bossios A
Conference publication: ANNALS OF THE RHEUMATIC DISEASES. 2025;84
RED FLAGS RAISING SUSPICION OF EOSINOPHILIC GRANULOMATOSIS WITH POLYANGIITIS (EGPA): RESULTS FROM THE EUROPEAN EGPAWARE DELPHI STUDY
Hellmich B; Bossios A; Domingo-Rivas C; Emmi G; Ponte C; Solans-Laque MR; Rua-Figueroa IJ; Vaglio A; Vassilopoulos D; Brembilla G; Kallinikou N; Terrier B
Meeting abstract: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2025;211:a3503
Suppression of the Anti-inflammatory Cytokine Il-38 in Moderate to Severe COPD
Etienne S; Bandeira E; Lazarinis N; Ramos-Ramirez P; Brundin B; Panagiotou A; Wheelock AM; Ridderby A; Ehlin A; Bossios A; Skold M; Linden A
Meeting abstract: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2025;211:a1355
IL-26 as a Potential Biomarker in Moderate to Severe COPD at a Tertiary Center
Bandeira E; Lazarinis N; Brundin B; Ramirez PR; Panagiotou A; Etienne S; Ridderby A; Ehlin A; Wheelock AM; Bossios A; Skold MC; Linden A
Editorial comment: EUROPEAN RESPIRATORY JOURNAL. 2025;65(4):2500044
Who really responds to asthma biologics? The clue lies in the journey before treatment
Yang F; Bossios A
Review: RESPIRATORY RESEARCH. 2025;26(1):77
Pulmonary microbiology and microbiota in adults with non-cystic fibrosis bronchiectasis: a systematic review and meta-analysis
Wang Y; Xiao J; Yang X; Liu Y; Du J; Bossios A; Zhang X; Su G; Wu L; Zhang Z; Lundborg CS
Review: LANCET RESPIRATORY MEDICINE. 2025;13(1):80-91
An international consensus on the use of asthma biologics in pregnancy.
Naftel J; Jackson DJ; Coleman M; d'Ancona G; Heaney LG; Dennison P; Bossios A; Rupani H
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2024;64:pa743
Characteristics and treatment escalation of severe uncontrolled asthma patients in primary care in Sweden
Konradsen JR; Packham S; Syk J; Bossios A; Stridsman C
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2024;64:pa4045
Abnormal spirometry in pediatric asthma - real-life application of the updated ATS/ERS guidelines.
Stridsman C; Backman H; Vanfleteren L; Asarnoj A; Bossios A; Konradsen J
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2024;64:pa3984
Use of oral corticosteroids in adults with asthma in Swedish primary care
Konradsen JR; Syk J; Stenberg H; Vanfleteren LE; Bossios A; Stridsman C
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2024;64:oa3659
The bronchodilator response in childhood asthma, a comparison of ATS/ERS and GINA criteria in a register-based cohort.
Stridsman C; Van Fleteren L; Asarnoj A; Bossios A; Konradsen J
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2024;64:pa4192
Microbiology in Swedish patients with bronchiectasis and comorbid airway disease: Data from a tertiary European Bronchiectasis registry (EMBARC) center
Osman N; Ghosh P; Sande M; Lazarinis N; Chalmers JD; Linden A; Bossios A
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2024;64:pa3319
Infection with P. aeruginosa and H. influenzae in relation to QoL and symptoms in bronchiectasis patients requiring intravenous antibiotics; data from a European Bronchiectasis Registry (EMBARC) center.
Ghosh P; Osman N; Sande M; Lazarinis N; Chalmers JD; Linden A; Bossios A
Meeting abstract: EUROPEAN RESPIRATORY JOURNAL. 2024;64:pa1227
Assessment of small airway dysfunction and symptoms in COPD
Lazarinis N; Panagiotou A; Ramos Ramirez P; Ehlin A; Ridderby A; Pournaras N; Bossios A; Linden A
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2024;64:pa3284
Pulmonary microbiology in adults with non-cystic fibrosis bronchiectasis: A systematic review and meta-analysis
Wang Y; Xiao J; Yang X; Liu Y; Du J; Bossios A; Zhang X; Su G; Wu L; Zhang Z; Lundborg CS
Meeting abstract: EUROPEAN RESPIRATORY JOURNAL. 2024;64:pa4847
Adiponectin modulates IL-10 production byT regulatory type 1 cells in allergic inflammation
Ramos Ramirez P; Malmhall C; Radinger M; Bossios A
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2024;64:pa2375
Highly symptomatic patients have an increased risk of exacerbations and benefit from long-term macrolide treatment in Bronchiectasis
Vidal OS; Stobo J; Perea L; Gao Y-H; Spinou A; Polverino E; Ringshausen F; Vendrell M; Burgel P-R; Haworth CS; Loebinger MR; Lorent N; Dhar R; Choi H; Chotirmall S; Hurst JR; Brown JS; Mcdonnell M; van der Eerden M; Kauppi P; Johnson E; Menendez R; Dimakou K; Bossios A; Crichton ML; Torres A; Welte T; Blasi F; Shteinberg M; Elborn SJ; Goeminne PC; Aliberti S; Jayaram L; Karalus N; Taylor SL; Martin ML; Burr L; Wong C; De Soyza A; Terpstra L; Altenburg J; Boersma W; Chalmers J
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2024;64:OA3766
The Asthma Control Test as a predictive tool for hospitalization and death
Sundbaum JK; Selberg S; Vanfleteren LGW; Bossios A; Konradsen JR; Stridsman C
Meeting abstract: EUROPEAN RESPIRATORY JOURNAL. 2024;64:pa482
Severe Asthma Multimorbidity Clusters Across Europe; Findings From SHARP
Freeman A; Bansal A; Rink S; Frankemoelle B; Singh M; Jacob S; Bossios A; Schleich F; Popovic S; Sergejeva S; Zervas E; Csoma Z; Grisle I; Bieksiene K; Ten Brinke A; Kuna P; Mihaltan F; Hromis S; Dahlen B; Yasinska V; Gemicioglu B; Skrgat S; Kurukulaaratchy R
Meeting abstract: EUROPEAN RESPIRATORY JOURNAL. 2024;64:pa481
Multimorbidity burden in severe asthma across the SHARP CRC
Freeman A; Bansal A; Rink S; Frankemolle B; Singh M; Sont J; Bossios A; Schleich F; Popovic SG; Sergejeva S; Zervas E; Csoma Z; Grisle I; Bieksiene K; Ten Brinke A; Kuna P; Mihaltan F; Hromis S; Dahlen B; Yasinska V; Gemicioglu B; Skrgat S; Kurukulaaratchy RJ
Meeting abstract: EUROPEAN RESPIRATORY JOURNAL. 2024;64:pa4495
High-dose inhaled corticosteroid use associated with increased cardiovascular risk in patients with asthma
von Bulow A; Hansen S; Sandin P; Ernstsson O; Cooper A; Geale K; Lehtimaki L; Ulrik C; Aarli BB; Ilmarinen P; Packham S; Hassan G; Backer V; Altraja A; Backman H; Kauppi P; Sverrild A; Yasinska V; Kilpelainen M; Viinanen A; Karjalainen J; Bossios A; Porsbjerg C; Kankaanranta H; Janson C
Meeting abstract: EUROPEAN RESPIRATORY JOURNAL. 2024;64:pa4008
Initial data analysis of the SHARP CRC patient population reveals a large heterogeneity among European patients with severe asthma
Fouka E; Bansal AT; Jaun F; Hakansson KEJ; Bieksiene K; Bourdin A; Butler M; Canonica GW; Csoma Z; Dahlen B; Gemicioglu B; Grisle I; Heaney L; Heffler E; Hromis S; Kuna P; Leuppi J; Louis R; Oureiro C; Luoviksdottir D; Mihaltan F; Popovic SG; Ramos-Barbon D; Sedlak V; Sergejeva S; Skrgat S; Ten Brinke A; Yasinska V; Zervas E; Schleich F; Porsbjerg C; Bossios A
Meeting abstract: EUROPEAN RESPIRATORY JOURNAL. 2024;64:pa3938
Characteristics of never-, switching, and persisting users of biologics for severe asthma - SHARP-CRC study
Hakansson KEJ; Bansal A; Fouka E; Jaun F; Ten Brinke A; Dahlen B; Gemicioglu B; Zervas E; Mihaltan F; Grisle I; Samitas K; Bieksiene K; Kuna P; Skrgat S; Popovic SG; Hromis S; Sergejeva S; Yasinska V; Csoma Z; Schleich F; Porsbjerg C; Bossios A
Meeting abstract: EUROPEAN RESPIRATORY JOURNAL. 2024;64:pa3089
Characteristics of severe asthma patients requiring ICU treatment across the SHARP CRC
Fouka E; Bansal AT; Hakansson KEJ; Jaun F; Bieksiene K; Butler M; Csoma Z; Dahlen B; Gemicioglu B; Grisle I; Hromis S; Kuna P; Mihaltan F; Popovic SG; Sedlak V; Sergejeva S; Skrgat S; Ten Brinke A; Yasinska V; Zervas E; Schleich F; Porsbjerg C; Bossios A
Meeting abstract: EUROPEAN RESPIRATORY JOURNAL. 2024;64:pa2149
European physician perspectives on multimorbidity in severe asthma: findings from SHARP CRC
Rink S; Freeman A; Bansal AT; Bossios A; Frankemolle B; Schleich F; Sont JK; Singh M; Bieksiene K; Bourdin A; Canonica GW; Csoma Z; Gemicioglu B; Grisle I; Popovic SG; Hromis S; Korn S; Kuna P; Loureiro C; Mihaltan F; Porsbjerg C; Ramos-Barbon D; Renaud L; Sergejeva S; Ten Brinke A; Yasinska V; Zervas E; Skrgat S; Kurukulaaratchy R
Meeting abstract: EUROPEAN RESPIRATORY JOURNAL. 2024;64:pa1763
Heterogeneity of comorbidities captured by European national severe asthma registries in SHARP CRC
Rink S; Freeman A; Bansal AT; Bossios A; Frankemoelle B; Schleich F; Sont JK; Singh M; Bieksiene K; Bourdin A; Canonica GW; Csoma Z; Gemicioglu B; Grisle I; Popovic SG; Hromis S; Korn S; Kuna P; Loureiro C; Mihaltan F; Porsbjerg C; Ramos-Barbon D; Renaud L; Sergejeva S; Ten Brinke A; Yasinska V; Zervas E; Skrgat S; Kurukulaaratchy R
Meeting abstract: EUROPEAN RESPIRATORY JOURNAL. 2024;64:pa1248
Clinical characteristics of severe asthma patients in Europe, according to the percentage of GDP spent on healthcare- a SHARP-CRC study
Jaun F; Bansal AT; Fouka E; Hakansson KEJ; Bieksiene K; Bourdin A; Butler M; Canonica GW; Csoma Z; Dahlen B; Gemicioglu B; Grisle I; Heaney L; Heffler E; Hromis S; Kuna P; Mihaltan F; Leuppi JD; Loureiro C; Louis R; Luoviksdottir D; Ramos-Barbon D; Popovic SG; Samitas K; Sedlak V; Sergejeva S; Skrat S; Ten Brinke A; Yasinska V; Zervas E; Schleich F; Porsbjerg C; Bossios A
Meeting abstract: EUROPEAN RESPIRATORY JOURNAL. 2024;64:oa5571
Recurrent respiratory infections and allergy hallmarks at-risk progression to severe asthma
Bari EJ; Hansen S; Sandin P; Ernstsson O; Bossios A; Lehtmaki L; Geale K; Janson C; Ulrik C; Kankarantaa H; Arli B; Sverrild A; Von Bulow A; Viinanen A; Altraja A; Schmid JM; Dahlen B; Laerum BN; Ludviksdottir D; Backman H; Karjalainen J; Bjermer L; Hilberg O; Kauppi P; Lehmann S; Sandstroem T; Skjold T; Bjornsdottir US; Yasinska V; Backer V; Porsbjerg C; Kilpelaeinen M
Meeting abstract: EUROPEAN RESPIRATORY JOURNAL. 2024;64:oa3763
Dose-dependent association between inhaled corticosteroids and risk of corticosteroid related adverse events in asthma
von Bulow A; Hansen S; Sandin P; Ernstsson O; Cooper A; Geale K; Lehtimaki L; Ulrik C; Aarli BB; Ilmarinen P; Packham S; Hassan G; Backer V; Altraja A; Backman H; Kauppi P; Sverrild A; Yasinska V; Kilpelainen M; Viinanen A; Karjalainen J; Bossios AB; Porsbjerg C; Janson C; Kankaanranta H
Review: EXPERT REVIEW OF RESPIRATORY MEDICINE. 2024;18(7):539-552
Small airways disease in chronic obstructive pulmonary disease
Lazarinis N; Fouka E; Linden A; Bossios A
Corrigendum: EUROPEAN RESPIRATORY JOURNAL. 2024;64(1):2351689
Airway clearance management in people with bronchiectasis: data from the European Bronchiectasis Registry (EMBARC) (vol 63, 2301689, 2024)
Spinou A; Hererro-Cortina B; Aliberti S; Goeminne PC; Polverino E; Dimakou K; Haworth CS; Loebinger MR; De Soyza A; Vendrell M; Burgel PR; McDonnell M; Sutharsan S; Skrgat S; Maiz-Carro L; Sibila O; Stolz D; Kauppi P; Bossios A; Hill AT; Clifton I; Crichton ML; Walker P; Menendez R; Borecki S; Obradovic D; Nowinski A; Amorim A; Torres A; Lorent N; Welte T; Blasi F; Makek MJ; Shteinberg M; Boersma W; Elborn JS; Chalmers JD; Ringshausen FC
Editorial comment: FRONTIERS IN ALLERGY. 2024;5:1446656
Editorial: Exploring the role of adaptive immunity in chronic airway respiratory diseases
Fouka E; Bossios A; Steiropoulos P; Samitas K
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2024;209:a5173
Aspergillus Testing and Disease Outcomes in Bronchiectasis: Data From the EMBARC Registry
Pollock J; Goeminne PC; Aliberti S; Polverino E; Crichton ML; Ringshausen F; Dhar R; Vendrell M; Burgel P; Haworth C; De Soyza A; De Gracia J; Bossios A; Rademacher J; Gruenewaldt A; Mcdonnell MJ; Stolz D; Sibila O; van der Eerden M; Kauppi P; Hill AT; Wilson R; Redondo M; Munteanu O; Menendez R; Torress A; Welte T; Blasi F; Boersma W; Elborn J; Shteinberg M; Dimakou K; Shoemark A; Chalmers JD; Loebinger MR
Editorial comment: ERJ OPEN RESEARCH. 2024;10(2):00891-2023
ERS International Congress 2023: highlights from the Airway Diseases Assembly
Bergantini L; Baker J; Bossios A; Braunstahl G-J; Conemans LH; Lombardi F; Mathioudakis AG; Pobeha P; Ricciardolo FLM; Romero LPP; Schleich F; Snelgrove RJ; Trinkmann F; Uller L; Beech A
Letter: RESPIRATORY MEDICINE. 2024;222:107529
The interplay between obesity and blood neutrophils in adult-onset asthma
Backman H; Lindmark SW; Hedman L; Kankaanranta H; Warm K; Lindberg A; Bossios A; Ro E; Stridsman C
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2023;62:pa5283
Under-treated asthma in adults - a common problem
Konradsen JR; Selberg S; Odling M; Bossios A; Stridsman C
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2023;62:pa2848
Changes of QoL-B in bronchiectasis patients undergoing an outpatient intravenous antibiotic therapy; preliminary results from a tertiary European Multicenter Bronchiectasis Audit and Research Collaboration (EMBARC) centre.
Ghosh P; Sande M; Chalmers JD; Bossios A
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2023;62:pa2430
Small airways impairment and hyperinflation in patients with bronchiectasis; preliminary data from a tertiary center.
Lazarinis N; Ghosh P; Sande M; Lantz AS; Nielsen EW; Dahlen B; Bossios A
Meeting abstract: EUROPEAN RESPIRATORY JOURNAL. 2023;62:oa4334
Allergic inflammation modulates the adiponectin/adiponectin receptor 1 axis in lung regulatory T cells in vivo
Ramos Ramirez P; Malmhall C; Bossios A
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2023;207:a4790
Regulatory T Cells Expressing Toll-like Receptor 2 in Blood From Smokers With Stable Chronic Obstructive Pulmonary Disease
Linden A; Malmhall C; Molnar A; Andersson A; Sjostrand M; Bossios A
Review: ERJ OPEN RESEARCH. 2023;9(3):444-2022
Definitions of non-response and response to biological therapy for severe asthma: a systematic review
Khaleva E; Rattu A; Brightling C; Bush A; Bourdin A; Bossios A; Chung KF; Chaudhuri R; Coleman C; Djukanovic R; Dahlen S-E; Exley A; Fleming L; Fowler SJ; Gupta A; Hamelmann E; Koppelman GH; Melen E; Mahler V; Seddon P; Singer F; Porsbjerg C; Ramiconi V; Rusconi F; Yasinska V; Roberts G
Review: EUROPEAN RESPIRATORY JOURNAL. 2023;61(4):2200606
Development of Core Outcome Measures sets for paediatric and adult Severe Asthma (COMSA)
Khaleva E; Rattu A; Brightling C; Bush A; Bossios A; Bourdin A; Chung KF; Chaudhuri R; Coleman C; Dahlen S-E; Djukanovic R; Deschildre A; Fleming L; Fowler SJ; Gupta A; Hamelmann E; Hashimoto S; Hedlin G; Koppelman GH; Melen E; Murray CS; Pilette C; Porsbjerg C; Pike KC; Rusconi F; Williams C; Ahrens B; Alter P; Anckers F; van den Berge M; Blumchen K; Brusselle G; Clarke GW; Cunoosamy D; Dahlen B; Dixey P; Exley A; Frey U; Gaillard EA; Giovannini-Chami L; Grigg J; Hartenstein D; Heaney LG; Karadag B; Kaul S; Kull I; Licari A; Maitland-van der Zee AH; Mahler V; Schoos A-MM; Nagakumar P; Negus J; Nielsen H; Paton J; Pijnenburg M; Ramiconi V; Vilarnau SR; Principe S; Rutjes N; Saglani S; Seddon P; Singer F; Staudinger H; Turner S; Vijverberg S; Winders T; Yasinska V; Roberts G
Review: EUROPEAN RESPIRATORY JOURNAL. 2023;61(4):2201231
Identifying and appraising outcome measures for severe asthma: a systematic review
Rattu A; Khaleva E; Brightling C; Dahlen S-E; Bossios A; Fleming L; Chung KF; Melen E; Djukanovic R; Chaudhuri R; Exley A; Koppelman GH; Bourdin A; Rusconi F; Porsbjerg C; Coleman C; Williams C; Nielsen H; Davin E; Taverner P; Vilarnau SR; Roberts G
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2022;60:1710
Demographic and clinical features of Swedish patients with bronchiectasis; preliminary results from a tertiary EMBARC centre
Ghosh P; Gerhardson I; Bedi N; Cornacchini SB; Lazarinis N; Dahlen B; Chalmers JD; Bossios A
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2022;60:2387
Heterogeneity in the use of biologics for severe asthma in Europe: a SHARP ERS study
Frix A; Heaney LG; Dahlen B; Mihaltan F; Sergejeva S; Doberer D; Popovic-Grle S; Sedlak V; Lehtimaki L; Bourdin A; Korn S; Zervas E; Csoma Z; Luoviksdottir D; Butler M; Canonica GW; Grisle I; Bieksiene K; Ten Brinke A; Kuna P; Loureiro CC; Nenasheva N; Lazic Z; Skrgat S; Ramos-Barbon D; Leuppi J; Gemicioglu B; Bossios A; Porsbjerg CM; Bel EH; Djukanovic R; Louis R
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2022;60:3570
Biomarkers of coagulative properties in patients admitted with AECOPD
Kamstrup P; Sand JMB; Ulrik C; Janner J; Ronnow SR; Leeming DJ; Jensen SG; Wilcke T; Miravitlles M; Mathioudakis A; Lapperre T; Frikke-Schmidt R; Murray D; Itenov T; Bossios A; Dam S; Vestbo J; Biering-Sorensen T; Karsdal M; Jensen JS; Sivapalan P
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2022;60:1085
Beliefs about vaccination and relation to COVID-19 vaccination side-effects in asthma patients.
Bossios A; Bacon AM; Eger K; Paroczai D; Schleich F; Hanon S; Sergejeva S; Zervas E; Katsoulis K; Aggelopoulou A; Kostikas K; Gaki E; Rovina N; Csoma Z; Grisle I; Bieksiene K; Palacionyte J; Ten Brinke A; Hashimoto S; Mihaltan F; Nenasheva N; Zvezdin B; Cekerevac I; HromiS S; Cupurdija V; Lazic Z; Chaudhuri R; Smith SJ; Rupani H; Haitchi HM; Kurukulaaratchy R; Fulton O; Frankemolle B; Howarth P; Porsbjerg C; Bel EH; Djukanovic R; Hyland M
Letter: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE. 2022;10(5):1377-1379
COVID-19 vaccination in the setting of mastocytosis-Pfizer-BioNTech mRNA vaccine is safe and well tolerated
Lazarinis N; Bossios A; Gulen T
Review: JOURNAL OF ASTHMA AND ALLERGY. 2022;15:231-247
Sex Disparities in Asthma Development and Clinical Outcomes: Implications for Treatment Strategies
Zhang G-Q; Ermis SSO; Radinger M; Bossios A; Kankaanranta H; Nwaru B
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2021;58:pa3119
Adult women with asthma and diabetes have increased body weight and fat percentage compared to women with only diabetes
Bossios A; Andersson DP; Eriksson-Hogling D; Ryden M
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2021;58:pa2006
Translation and validation of the Qualityof-Life Bronchiectasis questionnaire in Swedish, and correlation with clinical outcomes
Ghosh P; Gerhardson I; Middelveld R; Ek A; Panagiotou A; Dahlen S-E; Dahlen B; Bossios A
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2021;58:pa3120
Sensitization to aeroallergens is dominant in overweight to obese asthmatic males but not in females
Nwaru B; Kankaanranta H; Radinger M; Lotvall J; Lundback B; Ekerljung L; Bossios A
Editorial comment: CHEST. 2021;160(1):3-4
Hormone Replacement Therapy and Asthma A Double-Edged Sword
Bossios A
Editorial comment: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE. 2021;9(7):2689-2690
Inflammatory T2 Biomarkers in Severe Asthma Patients: The First Step to Precision Medicine
Bossios A
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2020;56:2364
Asthma as a co-morbidity and cause of bronchiectasis: data from the European Bronchiectasis Registry (EMBARC)
Polverino E; Traversi L; Martinez-Garcia M; Shteinberg M; Bossios A; Dimakou K; Paggiaro P; Ghillas G; Adir Y; Ferri S; Spanevello A; Dente F; Aliberti S; Chalmers J
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2020;56:2049
Neutrophil-to-lymphocyte ratio in patients with bronchiectasis and its correlation with low-grade inflammation; preliminary results from a single tertiary center
Ghosh P; Gerhardson I; Dahlen B; Bossios A
Meeting abstract: EUROPEAN RESPIRATORY JOURNAL. 2020;56:3311
Adipokine mediators in asthma and COPD are affected by sex and age
Andersson LI; James A; Dahlen S-E; Bossios A
Meeting abstract: EUROPEAN RESPIRATORY JOURNAL. 2020;56:2046
Mepolizumab decreases urinary excretion of LTE4 in severe asthma
Yasinska V; Kolmert J; Zurita J; Quaranta A; Bossios A; Lazarinis N; Dahlen B; Wheelock CE; Dahlen S-E
Meeting abstract: EUROPEAN RESPIRATORY JOURNAL. 2020;56:1104
Obese asthmatics with impaired FRC show increased eosinophilic inflammation
James A; Andersson L; Dahlen S-E; Bossios A
Editorial comment: EXPERT REVIEW OF RESPIRATORY MEDICINE. 2020;14(6):543-545
Sex steroid hormones and asthma in women: state-of-the-art and future research perspectives
Zhang G-Q; Bossios A; Radinger M; Nwaru BI
Editorial comment: EUROPEAN RESPIRATORY JOURNAL. 2020;55(4):1902476
NORDSTAR: paving the way for a new era in asthma research
Geale K; Darabi H; Lindh M; Wahl HF; Strom O; Cao H; Alvares L; Dodge R; Loefroth E; Altraja A; Backer V; Backman H; Bjermer L; Bossios A; Aarli BB; Dahlen B; Hilberg O; Janson C; Kankaanranta H; Karjalainen J; Kauppi P; Kilpelainen M; Lehmann S; Lehtimaki L; Lundback B; Sandstrom T; Ulrik CS; Sverrild A; Viinanen A; von Bulow A; Yasinska V; Porsbjerg C
Review: ALLERGY. 2020;75(3):546-560
New biological treatments for asthma and skin allergies
Eyerich S; Metz M; Bossios A; Eyerich K
Review: ALLERGO JOURNAL. 2020;29(4):14-27
Anwendung von Biologika bei allergischen und Typ-2-entzündlichen Erkrankungen in der aktuellen Covid-19-Pandemiea, b, c
Klimek L; Pfaar O; Worm M; Eiwegger T; Hagemann J; Ollert M; Untersmayr E; Hoffmann-Sommergruber K; Vultaggio A; Agache I; Bavbek S; Bossios A; Casper I; Chan S; Chatzipetrou A; Vogelberg C; Firinu D; Kauppi P; Kolios A; Kothari A; Matucci A; Palomares O; Szépfalusi Z; Pohl W; Hötzenecker W; Rosenkranz A; Bergmann K-C; Bieber T; Buhl R; Buters J; Darsow U; Keil T; Kleine-Tebbe J; Lau S; Maurer M; Merk H; Mösges R; Saloga J; Staubach P; Jappe U; Rabe C; Rabe U; Vogelmeier C; Biedermann T; Jung K; Schlenter W; Ring J; Chaker A; Wehrmann W; Becker S; Freudelsperger L; Mülleneisen N; Nemat K; Czech W; Wrede H; Brehler R; Fuchs T; Tomazic P-V; Aberer W; Fink Wagner A; Horak F; Wöhrl S; Niederberger-Leppin V; Pali-Schöll I; Roller-Wirnsberger R; Spranger O; Valenta R; Akdis M; Matricardi PM; Spertini F; Khaltaev N; Michel J-P; Nicod L; Schmid-Grendelmeier P; Idzko M; Hamelmann E; Jakob T; Werfel T; Wagenmann M; Taube C; Jensen-Jarolim E; Korn S; Hentges F; Schwarze J; O Mahony L; Knol E; Del Giacco S; Chivato T; Bousquet J; Zuberbier T; Akdis C; Jutel M
Letter: ALLERGY. 2019;74(11):2244-2248
Severe asthma: Entering an era of new concepts and emerging therapies: Highlights of the 4th international severe asthma forum, Madrid, 2018
Seys SF; Quirce S; Agache I; Akdis CA; Alvaro-Lozano M; Antolin-Amerigo D; Bjermer L; Bobolea I; Bonini M; Bossios A; Brinkman P; Bush A; Calderon M; Canonica W; Chanez P; Couto M; Davila I; Del Giacco S; Del Pozo V; Erjefalt JS; Gevaert P; Hagedoorn P; Heaney LG; Heffler E; Hellings PW; Jutel M; Kalayci O; Kurowski MM; Loukides S; Nair P; Palomares O; Polverino E; Sanchez-Garcia S; Sastre J; Schwarze J; Spanevello A; Ulrik CS; Usmani O; Van den Berge M; Vasakova M; Vijverberg S; Diamant Z
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2019;54:pa2564
Oral corticosteroid use in Swedish and Finnish severe asthma patients
Geale K; Darabi H; Lindh M; Alvares L; Dodge R; Altraja A; Backer V; Bjermer L; Bossios A; Janson C; Kankaanranta H; Kauppi P; Lehtimaki L; Ulrik CS; Viinanen A; Porsbjerg C
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2019;54:pa2765
Increased relative levels of IgG subclasses, mainly IgG3, in patient with bronchiectasis and history of exacerbations; preliminary results from a single tertiary center
Ghosh P; Gerhardson I; Dahlen B; Bossios A
Meeting abstract: EUROPEAN RESPIRATORY JOURNAL. 2019;54:pa3346
Oral steroids induce leptin and adiponectin in subjects with airway obstructive diseases
Andersson LI; James A; Dahlen B; Dahlen S-E; Bossios A
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2018;52:pa1143
Late Breaking Abstract - NORdic Database for aSThmA Research (NORDSTAR): Swedish and Finnish patients
Geale K; Darabi H; Eklund O; Lindh M; Wahl HF; Strom O; Cao H; Alvares L; Dodge R; Loefroth E; Altraja A; Backer V; Backman H; Bjermer L; Bossios A; Dahlen B; Janson C; Kankaanranta H; Kauppi P; Kilpelainen M; Lehtimaki L; Sandstrom T; Ulrik CS; Viinanen A; Porsbjerg C
Conference publication: ANNALS OF THE RHEUMATIC DISEASES. 2018;77:a26
P030 Serum levels of immunoglobulin d and factors influencing the levels in rheumatoid arthritis
Gravina G; Erlandsson M; Bossios A; Ekerljung L; Malmhäll C; Lundbäck B; Mikael B; Bokarewa M
Conference publication: ANNALS OF THE RHEUMATIC DISEASES. 2018;77:a23-a24
P023 Smoking is associated with low serum levels of soluble PD-l1 in rheumatoid arthritis
Wasén C; Erlandsson M; Bossios A; Ekerljung L; Malmhäll C; Silfverswärd ST; Pullerits R; Lundbäck B; Bokarewa M
Conference publication: ANNALS OF THE RHEUMATIC DISEASES. 2018;77:A23-A24
SMOKING IS ASSOCIATED WITH LOW SERUM LEVELS OF SOLUBLE PD-L1 IN RHEUMATOID ARTHRITIS
Wasen C; Erlandsson M; Bossios A; Ekerljung L; Malmhall C; Silfversward ST; Pullerits R; Lundback B; Bokarewa MI
Conference publication: ANNALS OF THE RHEUMATIC DISEASES. 2018;77:A26
SERUM LEVELS OF IMMUNOGLOBULIN D AND FACTORS INFLUENCING THE LEVELS IN RHEUMATOID ARTHRITIS
Gravina G; Erlandsson MC; Bossios A; Ekerljung L; Malmhall C; Lundback B; Mikael B; Bokarewa MI
Review: ERJ OPEN RESEARCH. 2018;4(1):163-2017
Research highlights from the 2017 ERS International Congress: airway diseases in focus
Andersson C; Bonvini SJ; Horvath P; Marquez E; Satia I; Kirkham P; Schleich F; Idzko M; Gosens R; Luis Lopez-Campos J; Bossios A; Usmani O; Spanevello A; Adcock IM; Mathioudakis AG
Conference publication: EUROPEAN JOURNAL OF IMMUNOLOGY. 2017;47:123
Smoking is associated with low serum levels of soluble PD-L1 in rheumatoid arthritis
Wasen C; Erlandsson M; Bossios A; Ekerljung L; Malmhall C; Silfversward ST; Lundback B; Bokarewa MI
Meeting abstract: EUROPEAN RESPIRATORY JOURNAL. 2016;48:pa1101
Weight gain alters adiponectin receptor 1 expression on lung-resident Foxp3+Helios+ regulatory T cells: Implications during allergic airway inflammation?
Ramos Ramirez P; Malmhall C; Johansson K; Lotvall J; Bossios A
Conference publication: ALLERGY. 2016;71:82-83
Adiponectin receptor 1 expression on adipose tissue Foxp3+Helios+ regulatory T cells is reduced upon weight gain
Ramos-Ramirez P; Malmhall C; Johansson K; Lotvall J; Bossios A
Conference publication: ALLERGY. 2016;71:62
Increased weight might be associated with decreased level of allergic sensitization in a general population
Mincheva R; Bossios A; Lotvall J; Lundback B; Ekerljung L
Conference publication: ARTHRITIS & RHEUMATOLOGY. 2015;67
Survivin Links Smoking and High Prevalence of Rheumatoid Arthritis in Women
Turkkila M; Bossios A; Erlandsson M; Andersson KME; Silfversward ST; Rolf M; Ekerljung L; Malmhall C; Lundback B; Bokarewa M
Conference publication: ALLERGY. 2015;70:164
B cell activating factor (BAFF) in severe asthma: a possible regulator of eosinophilic inflammation
Samitas K; Malmhall C; Radinger M; Lu Y; Deak T; Semitekolou M; Gaga M; Sjostrand M; Lotvall J; Bossios A
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2015;46:pa5102
Tobacco smoke causes release of IL-16 protein from NK cells in vitro
Andersson A; Malmhall C; Linden A; Bossios A
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2015;46:pa3347
Survivin in patients with chronic obstructive pulmonary disease
Bossios A; Ekerljung L; Turkkila M; Malmhall C; Erlandsson M; Silfversward ST; Lundback B; Bokarewa M
Review: ALLERGY. 2015;70(7):727-754
EAACI IG Biologicals task force paper on the use of biologic agents in allergic disorders
Boyman O; Kaegi C; Akdis M; Bavbek S; Bossios A; Chatzipetrou A; Eiwegger T; Firinu D; Harr T; Knol E; Matucci A; Palomares O; Schmidt-Weber C; Simon H-U; Steiner UC; Vultaggio A; Akdis CA; Spertini F
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2014;44
Increased infl of progenitor B cell subsets in the lung eth diverse levels of in -situ proliferation and activation in a murine model of allergic inflammation
Samitas K; Malmhall C; Radinger M; Lu Y; Deak T; Sjostrand M; Lotvall J; Bossios A
Book chapter: EOSINOPHILS IN HEALTH AND DISEASE. 2013;p. 73-119
Chapter 5 Eosinophilopoiesis
Maltby S; McNagny KM; Ackerman SJ; Du J; Mori Y; Iwasaki H; Akashi K; Takatsu K; Rådinger M; Bossios A; Lötvall J; Lee NA
Conference publication: ALLERGY. 2012;67:312
T regulatory cell surface molecules expression differs between asthmatics with and without eosinophilia and non-asthmatics
Malmhall C; Bossios A; Radinger M; Sjostrand M; Lu Y; Lundback B; Lotvall J
Conference publication: ALLERGY. 2012;67:146
IL-33 regulates lung in situ eosinophilopoiesis by affecting their proliferation, survival and migration
Lu Y; Sjostrand M; Radinger M; Malmhall C; Lotvall J; Bossios A
Conference publication: ALLERGY. 2012;67:54
MicroRNA-155 is essential for Th2 mediated allergen-induced eosinophilic inflammation in the lung
Malmhall C; Moorthy N; Lu Y; Sjostrand M; Bossios A; Lotvall J; Radinger M
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2012;40
The impact of long-term tobacco smoking on circulating IL-16⁺ NK cells
Andersson A; Bossios A; Malmhall C; Sjostrand M; Houltz B; Qvarfordt I; Linden A
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2012;40
Circulating mature and progenitor eosinophils in patients with stable asthma express all major traffic related receptors
Lu Y; Malmhall C; Sjostrand M; Radinger M; Lundback B; Lotvall J; Bossios A
Review: RECENT PATENTS ON ANTI-INFECTIVE DRUG DISCOVERY. 2011;6(3):189-205
Current update on eosinophilic lung diseases and anti-IL-5 treatment.
Samitas K; Rådinger M; Bossios A
Conference publication: ALLERGY. 2011;66:656
Laser microdissection reveals different expression of pro-inflammatory genes in different lung microenvironments during allergic inflammation, relationship to T-effector cell distribution
Lu Y; Malmhall C; Serena E; Radinger M; Sjostrand M; Lotvall J; Bossios A
Conference publication: ALLERGY. 2011;66:520
Circulating T-bet⁺, GATA-3⁺, RORγt⁺ and FOXP3⁺ cells in individuals with eosinophilic and non-eosinophilic asthma
Malmhall C; Bossios A; Radinger M; Sjostrand M; Lu Y; Lundback B; Lotvall J
Conference publication: ALLERGY. 2011;66:153
Divergent effects of human rhinovirus versus respiratory syncytial virus-induced bronchiolitis in asthma phenotype development
Makrinioti H; Bossios A; Xepapadaki P; Megremis S; Tsolia M; Papadopoulos N
Conference publication: ALLERGY. 2011;66:25
Role of IL-33 in lung tissue eosinophilia in a murine model of allergic inflammation
Lu Y; Radinger M; Sjostrand M; Malmhall C; Lotvall J; Bossios A
Review: ALLERGY. 2011;66(4):458-468
Viruses and bacteria in acute asthma exacerbations - A GA2LEN-DARE* systematic review
Papadopoulos NG; Christodoulou I; Rohde G; Agache I; Almqvist C; Bruno A; Bonini S; Bont L; Bossios A; Bousquet J; Braido F; Brusselle G; Canonica GW; Carlsen KH; Chanez P; Fokkens WJ; Garcia-Garcia M; Gjomarkaj M; Haahtela T; Holgate ST; Johnston SL; Konstantinou G; Kowalski M; Lewandowska-Polak A; Lodrup-Carlsen K; Makela M; Malkusova I; Mullol J; Nieto A; Eller E; Ozdemir C; Panzner P; Popov T; Psarras S; Roumpedaki E; Rukhadze M; Stipic-Markovic A; Bom AT; Toskala E; van Cauwenberge P; van Drunen C; Watelet JB; Xatzipsalti M; Xepapadaki P; Zuberbier T
Conference publication: ALLERGY. 2010;65:642
Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages
Lasser C; Alikhani SV; Ekstrom K; Bossios A; Sjostrand M; Gabrielsson S; Valadi H; Lotvall J
Conference publication: ALLERGY. 2010;65:495-496
CD8-/- and wild-type mice display similar pulmonary IL-5Rα⁺ eosinophilia and local cytokine milieu in a mouse model of allergic inflammation
Malmhall C; Lu Y; Sjostrand M; Jeurink P; Radinger M; Lotvall J; Bossios A
Conference publication: ALLERGY. 2010;65:494
Newly produced B cells show different levels of turn-over and in-situ proliferation in the lung of allergen exposed mice
Bossios A; Samitas K; Lu Y; Malmall C; Deak T; Radinger M; Sjostrand M; Lotvall J
Conference publication: ALLERGY. 2010;65:349
Blood and nasal lavage eosinophils in rhinitis and asthma. Results from the west Sweden asthma study
Sjostrand M; Ekerljung L; Bossios A; Lundback B; Lotvall J
Conference publication: ALLERGY. 2010;65:224-225
Epidemiology of multi-symptom asthma: results from the West Sweden Asthma Study
Ekerljung L; Bossios A; Lotvall J; Lundback B
Conference publication: ALLERGY. 2010;65:128
The relative presence of Th1, Th2, Th17 and Tregs in lung tissue after allergen exposure in a murine model of allergic inflammation
Lu Y; Sjostrand M; Malmhall C; Lotvall J; Bossios A
Conference publication: ALLERGY. 2010;65:7
Quantitative expression of osteopontin in nasal mucosa of patients with allergic rhinitis: effects of pollen exposure and nasal steroid treatment
O'Neil S; Malmhall C; Samitas K; Bossios A; Sjostrand M; Lotvall J
Review: ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS. 2010;58(3):209-225
B Cells: From Early Development to Regulating Allergic Diseases
Samitas K; Lotvall J; Bossios A
Conference publication: JOURNAL OF IMMUNOLOGY. 2009;182:80.10
Interleukin-5 producing CD34+hematopoietic progenitor cells in eosinophilic diseases
Sjostrand M; Bossios A; Samitas K; Maimhall C; Gaga M; Lotvall J
Conference publication: JOURNAL OF IMMUNOLOGY. 2009;182:47.14
Increased number of systemic T regulatory cells but not Th1 or Th2 cells in tobacco smokers
Malmhall CA; Andersson A; Jackute J; Houltz B; Lotvall J; Linden A; Bossios A
Conference publication: ALLERGY. 2009;64:139
Interleukin-33 expression in a mouse model of allergic airway inflammation
Sjostrand M; Bossios A; Radinger M; Lotvall J
Conference publication: ALLERGY. 2009;64:138-139
The absence of CD8+cells affects T regulatory cells and activated T helper cells in a mouse model of allergic inflammation
Malmhall C; Lu Y; Lotvall J; Bossios A
Conference publication: ALLERGY. 2009;64:136
Distribution of T-bet+, GATA-3+and Foxp3+cell in lung tissue after allergen exposure in a mouse model of allergic inflammation
Lu Y; Malmhall C; Lotvall J; Sjostrand M; Bossios A
Conference publication: ALLERGY. 2009;64:67
Human exosomes with and without RNA
Lasser C; Alikhani SV; Ekstrom K; Bossios A; Sjostrand M; Valadi H; Lotvall J
Conference publication: ALLERGY. 2008;63:337
Evaluation of lung eosinophilic inflammation in two main mouse allergic inflammation models BALB/C and C57BL/6
Lu Y; Bossios A; Sjostrand M; Lotvall J
Conference publication: ALLERGY. 2008;63:94-95
Detection and characterisation of exosomes of monocyte and human proinflammatory macrophage type I origin
Sjostrand M; Lasser C; Valadi H; Lightfoot A; Malmer A; Bossios A; Lotvall J
Conference publication: ALLERGY. 2007;62:132
Mucosal Th1/Th2 and Treg/Th2 ratio is maintained by nasal steroid treatment in allergic rhinitis patients
Malmhall C; Bossios A; Pullerits T; Lotvall J
Conference publication: ALLERGY. 2007;62:2
A 53-year-old woman with asthma and idiopathic hypereosinophilia showed increased bone marrow expression of IL-5 abolished after steroid treatment
Bossios A; Malmhall C; Lotvall J
Conference publication: ALLERGY. 2007;62:473
Glucocorticoids induce apoptosis in FOXP3⁺ cells in vitro
Malmhall C; Bossios A; Pullerits T; Lotvall J
Conference publication: ALLERGY. 2007;62:467
A comparison of BALB/C and C57BL/6 mice in a model of allergic inflammation
Lu Y; Bossios A; Jeurink P; Radinger M; Silverpil E; Lee J; Sjostrand M; Lotvall J
Conference publication: ALLERGY. 2007;62:452
Exosomes detected in human blood plasma
Alikhani VS; Malmer A; Ekstrom K; Bossios A; Sjostrand M; Lotvall J
Conference publication: ALLERGY. 2007;62:372
Exosomes contain a selective number of mRNA and microRNA
Valadi H; Ekstrom K; Bossios A; Sjostrand M; Lotvall J
Conference publication: ALLERGY. 2007;62:126
Differential proliferation rate among bronchial and nasal epithelial cells and their response to human rhinovirus induced cytotoxicity
Skevaki C; Georgiou V; Gaga M; Bossios A; Tiniakou I; Samitas K; Kafetzis D; Papadopoulos N
Conference publication: ALLERGY. 2007;62:101
Newly produced IL-5Ralpha+cells proliferate in the lung of allergenchallenged mice
Radinger M; Bossios A; Sjostrand M; Lee J; Lotvall J
Conference publication: ALLERGY. 2007;62:98
The presence of IL-5 enhances isotype switching to IgE also in CD4 knockout mice, while it does not overcome the decrease in OVA specific IgE secretion
Jeurink P; Radinger M; Bossios A; Lu Y; Savelkoul H; Lee J; Lotvall J
Conference publication: ALLERGY. 2007;62:69
Human rhinoviruses and house dust mites synergizes in the induction of NF-kB in bronchial epithelial cells
Bossios A; Skevaki C; Lotvall J; Gourgiotis D; Saxoni-Papageorgiou P; Johnston S; Papadopoulos N
Conference publication: ALLERGY. 2007;62:15
CD4+dominance and Th2 cytokine profile in lung microenvironment during allergic inflammation is a result of decreased CD8 and natural killer cells influx
Bossios A; Malmhall C; Jeurink P; Radinger M; Sjostrand M; Lotvall J
Review: ALLERGY. 2007;62(5):457-470
Mechanisms of virus-induced asthma exacerbations:: state-of-the-art.: A GA²LEN and InterAirways document
Papadopoulos NG; Xepapadaki P; Mallia P; Brusselle G; Watelet J-B; Xatzipsalti M; Foteinos G; van Drunen CM; Fokkens WJ; D'Ambrosio C; Bonini S; Bossios A; Lotvall J; van Cauwenberge P; Holgate ST; Canonica GW; Szczeklik A; Rohde G; Kimpen J; Pitkaranta A; Makela M; Chanez P; Ring J; Johnston SL
Conference publication: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2006;117(2):S311
An IgE antibody reduce the release of IL-5 from mouse OVA treated CD34+ hematopoietic progenitor cells in vitro
Sjöstrand M; Alm A; Bossios A; Rådinger M; Lötvall J
Conference publication: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2006;117(2):S255
Newly produced CD4+cells in bone marrow after airway allergen exposure
Bossios A; Malmhäll C; Rådinger M; Mannerås L; Petersson L; Sjostrand M; Lötvall J
Conference publication: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2006;117(2):S244
Effect of nasal steroid treatment on mucosal FOXP3+cells in allergic rhinitis patients
Malmhäll C; Bossios A; Pullerits T; Lötvall J
Conference publication: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2006;117(2):S69
Analysis of global protein content in mast cell exosomes
Ekström K; Valadi H; Almqvist N; Bossios A; Sjöstrand M; Lötvall J
Conference publication: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2006;117(2):S58
Newly produced eosinophil-lineage committed cells proliferate in the lung of allergen-challenged mice
Radinger M; Bossios A; Sjöstrand M; Lötvall J
Conference publication: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2006;117(2):S56
Eotaxin-1 & -2 induced migration of CD34+/CCR3+bone marrow and blood eosinophil-lineage committed cells
Lötvall J; Bossios A; Sjötrand M; Lee JJ; Radinger M
Published conference paper: CLINICAL INFECTIOUS DISEASES. 2004;39(5):681-686
Etiology of community-acquired pneumonia in hospitalized school-age children: Evidence for high prevalence of viral infections
Tsolia MN; Psarras S; Bossios A; Audi H; Paldanius M; Gourgiotis D; Kallergi K; Kafetzis DA; Constantopoulos A; Papadopoulos NG
Doctoral thesis: 2004
Synetrgy of allergens and rhinoviruses at in-vitro induction of exacerbation in allergic-asthmatic inflammation
Bossios A
Conference publication: ALLERGY. 2002;57:126-127
Induction of eotaxin and eotaxin-2 in nasal secretions of patients with seasonal respiratory allergy
Bossios A; Gourgiotis D; Psarras S; Volonaki E; Johnston SL; Saxoni-Papageorgiou F; Papadopoulos NG
Conference publication: ALLERGY. 2002;57:295
Association of respiratory viral infections with disease exacerbations in patients with allergen-driven seasonal asthma and hay fever
Papadopoulos NG; Psarros F; Manoussakis E; Xatzipsalti M; Bossios A; Syrigou E; Kassimos D; Baibas N; Gourgiotis D; Saxoni-Papageorgiou F
Conference publication: ALLERGY. 2002;57:295-296
Airway hyperresponsiveness in atopic and non-atopic asthmatic children following respiratory tract infections
Xepapadaki P; Papadopoulos NG; Bossios A; Syrigou E; Manoussakis E; Xatzipsalti M; Saxoni-Papageorgiou F
Conference publication: ALLERGY. 2002;57:296
Rhinovirus infection stimulates production of fibroblast growth factor-2 by airway epithelial and stromal cells
Psarras S; Xatzipsalti M; Volonaki E; Bossios A; Gourgiotis D; Saxoni-Papageorgiou F; Johnston SL; Papadopoulos NG
Conference publication: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 1997;99(1):598
Lymphocyte proliferation to cow's milk (CM) proteins correlates with sensitization and antigen load in CM allergic infants.
Papageorgiou PS; Papadopoulos N; Surigou A; Bossios A; Manou O
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Forskningsbidrag

Severe Asthma with bronchiectasis – exploring the role of regulatory T cells.
Hjärt-Lungfonden
1 January 2025 - 31 December 2027
Indoor biomass burning contributes to significant particulate matter exposure, chronic human health burden, and an economic drain in rural households
Swedish Research Council
1 January 2023 - 31 December 2026
Biomass burning for cooking and heating produces a toxic cocktail of particulate matter (PM) and gaseous pollutants, resulting in chronic lung issues. Around 0.5-0.6 million deaths occur annually in India, mainly in the Indo-Gangetic Plains, from exposure to indoor air pollutants, indicating the multifaceted healthcare, economic and environmental burden in households, where biomass burning prevails. And yet, ground-based indoor exposure data are sparse, there is poor awareness about air pollution, and clean energy initiatives are lagging. We hypothesize that biomass combustion and PM exposure is related to specific pollutant classes (triggers) and their synergistic interactions, which trace early metabolic changes in plasma to diagnose asthma, lung aging, and chronic pulmonary obstructions. We aim to 1) conduct socioeconomic and health surveys and develop real-time indoor pollutant monitoring using automated sensor networks, 2) analyze organic compounds and oxidative metals that cause pulmonary stress, and 3) identify novel biomarkers in plasma and combine this with integrative transcriptomics, epidemiological and environmental chemical data. The proposed synergistic and integrated work packages on PM characteristics and metabolomics will establish causality with exposure posing a breakthrough for early clinical diagnosis. This strategy will help healthcare measures and mitigation plans advance the UN Sustainable Development Goals 3 and 7 for better air quality and health.
Understanding the role of diabetes and bronchiectasis as sub-phenotypes in severe asthma.
Hjärtlungfonden
1 January 2023 - 31 December 2025
Unfolding treatable traits of obesity and Bronchiectasis as sub-phenotypes in severe asthma.
Swedish Heart-Lung Foundation
1 January 2021 - 31 December 2022
Title: Coal-based economies in developing countries: An environmental, health and cost evaluation around mega thermal power plants
Swedish Research Council
1 January 2021 - 31 December 2023
Unfolding treatable traits of obesity and Bronchiectasis as sub-phenotypes in severe asthma.
Hjärt-Lungfonden
1 January 2021 - 31 December 2022
Makrofagers ursprung och funktion i bronkiektasier hos människa
Swedish Heart-Lung Foundation
1 January 2020 - 31 December 2022
Characterisation of obesity as sub-phenotype in severe asthma
Swedish Heart-Lung Foundation
1 January 2019 - 31 December 2021
Characterization of obesity and bronchiectasis as sub-phenotypes in severe asthma
Swedish Heart-Lung Foundation
1 January 2019 - 31 December 2020

Anställningar

Senior Forskare, Institutet för miljömedicin, Karolinska Institutet, 2022-

Examina och utbildning

Docent, Lungsjukdomar, Karolinska Institutet, 2021

Nyheter från KI

Kalenderhändelser från KI

Audiovisuella medier

Media (audio-visual): YOUTUBE. 2023
The SHARP podcast: an interview with Apostolos Bossios
Bossios A