Anoop Tholamplackil Ambikan

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: BRAIN BEHAVIOR AND IMMUNITY. 2025;123:914-927
SARS-CoV-2 variants mediated tissue-specific metabolic reprogramming determines the disease pathophysiology in a hamster model
Sardarni UK; Ambikan A; Acharya A; Johnson S; Avedissian SN; Vegvari A; Neogi U; Byrareddy SN
Article: ISCIENCE. 2024;27(8):110501
Differential immunometabolic responses to Delta and Omicron SARS-CoV-2 variants in golden syrian hamsters
Rajaiah R; Pandey K; Acharya A; Ambikan A; Kumar N; Guda R; Avedissian SN; Montaner LJ; Cohen SM; Neogi U; Byrareddy SN
Article: ISCIENCE. 2024;27(4):109346
Inflammatory, metabolic, and sex-dependent gene-regulatory dynamics of microglia and macrophages in neonatal hippocampus after hypoxia-ischemia
Di Martino E; Ambikan A; Ramskold D; Umekawa T; Giatrellis S; Vacondio D; Romero AL; Galan MG; Sandberg R; Aden U; Lauschke VM; Neogi U; Blomgren K; Kele J
Article: NATURE COMMUNICATIONS. 2024;15(1):2532
Parechovirus infection in human brain organoids: host innate inflammatory response and not neuro-infectivity correlates to neurologic disease
Capendale PE; Garcia-Rodriguez I; Ambikan AT; Mulder LA; Depla JA; Freeze E; Koen G; Calitz C; Sood V; de Sa RV; Neogi U; Pajkrt D; Sridhar A; Wolthers KC
Article: VIRUS RESEARCH. 2024;341:199306
Temporal cytokine storm dynamics in dengue infection predicts severity
Bhatt P; Varma M; Sood V; Ambikan A; Jayaram A; Babu N; Gupta S; Mukhopadhyay C; Neogi U
Article: ALLERGY. 2024;79(1):65-79
Rural and urban exposures shape early life immune development in South African children with atopic dermatitis and nonallergic children
Lunjani N; Ambikan AT; Hlela C; Levin M; Mankahla A; Heldstab-Kast JI; Boonpiyathad T; Tan G; Altunbulakli C; Gray C; Nadeau KC; Neogi U; Akdis CA; O'Mahony L
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2023;120(37):e2304722120
Systems-level temporal immune- metabolic profile in Crimean-Congo hemorrhagic fever virus infection
Ambikan AT; Elaldi N; Akusjaervi SS; Bagci B; Pektas AN; Hewson R; Bagci G; Arasli M; Appelberg S; Mardinoglu A; Sood V; Vegvari A; Benfeitas R; Gupta S; Cetin I; Mirazimi A; Neogi U
Article: AIDS. 2023;37(7):1023-1033
Role of myeloid cells in system-level immunometabolic dysregulation during prolonged successful HIV-1 treatment
Svensson Akusjarvi S; Krishnan S; Ambikan AT; Mikaeloff F; Munusamy Ponnan S; Vesterbacka J; Lourda M; Nowak P; Sonnerborg A; Neogi U
Article: LIFE SCIENCE ALLIANCE. 2022;5(9):e202201405
Genome-scale metabolic models for natural and long-term drug-induced viral control in HIV infection
Ambikan AT; Svensson-Akusjarvi S; Krishnan S; Sperk M; Nowak P; Vesterbacka J; Sonnerborg A; Benfeitas R; Neogi U
Article: CELL SYSTEMS. 2022;13(8):665-681.e4
Multi-omics personalized network analyses highlight progressive disruption of central metabolism associated with COVID-19 severity
Ambikan AT; Yang H; Krishnan S; Akusjarvi SS; Gupta S; Lourda M; Sperk M; Arif M; Zhang C; Nordqvist H; Ponnan SM; Sonnerborg A; Treutiger CJ; O'Mahony L; Mardinoglu A; Benfeitas R; Neogi U
Article: ELIFE. 2022;11:e76071
Multi-omics insights into host-viral response and pathogenesis in Crimean-Congo hemorrhagic fever viruses for novel therapeutic target
Neogi U; Elaldi N; Appelberg S; Ambikan A; Kennedy E; Dowall S; Bagci BK; Gupta S; Rodriguez JE; Svensson-Akusjarvi S; Monteil V; Vegvari A; Benfeitas R; Banerjea A; Weber F; Hewson R; Mirazimi A
Article: COMMUNICATIONS BIOLOGY. 2022;5(1):357
Peripheral blood CD4⁺CCR6⁺ compartment differentiates HIV-1 infected or seropositive elite controllers from long-term successfully treated individuals
Svensson Akusjarvi S; Krishnan S; Jutte BB; Ambikan AT; Gupta S; Rodriguez JE; Vegvari A; Sperk M; Nowak P; Vesterbacka J; Svensson JP; Sonnerborg A; Neogi U
Article: ISCIENCE. 2022;25(1):103607
Integrative proteo-transcriptomic and immunophenotyping signatures of HIV-1 elite control phenotype: A cross-talk between glycolysis and HIF signaling
Akusjarvi SS; Ambikan AT; Krishnan S; Gupta S; Sperk M; Vegvari A; Mikaeloff F; Healy K; Vesterbacka J; Nowak P; Sonnerborg A; Neogi U
Article: HRB OPEN RESEARCH. 2022;5:31
Impact of Long COVID on health and quality of life.
O' Mahony L; Buwalda T; Blair M; Forde B; Lunjani N; Ambikan A; Neogi U; Barrett P; Geary E; O'Connor N; Dineen J; Clarke G; Kelleher E; Horgan M; Jackson A; Sadlier C
Article: MICROBIOLOGY SPECTRUM. 2021;9(2):e0047021-e00421
Deciphering the Role of Mucosal Immune Responses and the Cervicovaginal Microbiome in Resistance to HIV Infection in HIV-Exposed Seronegative (HESN) Women
Ponnan SM; Thiruvengadam K; Tellapragada C; Ambikan AT; Narayanan A; Kathirvel S; Mathayan M; Shankar J; Rajaraman A; Amanulla MA; Dinesha TR; Poongulali S; Saravanan S; Murugavel KG; Swaminathan S; Velu V; Shacklett B; Neogi U; Hanna LE
Article: JOURNAL OF VIROLOGY. 2021;95(18):e0047921-10.1128/jvi.00421
Fecal Metabolome Signature in the HIV-1 Elite Control Phenotype: Enrichment of Dipeptides Acts as an HIV-1 Antagonist but a Prevotella Agonist
Sperk M; Ambikan AT; Ray S; Singh K; Mikaeloff F; Diez RC; Narayanan A; Vesterbacka J; Nowak P; Sonnerborg A; Neogi U
Article: BMC INFECTIOUS DISEASES. 2021;21(1):214
Increased acquired protease inhibitor drug resistance mutations in minor HIV-1 quasispecies from infected patients suspected of failing on national second-line therapy in South Africa
Obasa AE; Ambikan AT; Gupta S; Neogi U; Jacobs GB
Article: ISCIENCE. 2021;24(2):102111
Distinct lipid profile, low-level inflammation, and increased antioxidant defense signature in HIV-1 elite control status
Sperk M; Mikaeloff F; Svensson-Akusjarvi S; Krishnan S; Ponnan SM; Ambikan AT; Nowak P; Sonnerborg A; Neogi U
Article: FRONTIERS IN MICROBIOLOGY. 2021;12:627861
Genomic Insights Into Clinical Shiga Toxin-Producing Escherichia coli Strains: A 15-Year Period Survey in Jonkoping, Sweden
Bai X; Zhang J; Hua Y; Jernberg C; Xiong Y; French N; Lofgren S; Hedenstrom I; Ambikan A; Mernelius S; Matussek A
Article: AIDS. 2021;35(2):227-234
High-throughput sequencing reveals a high prevalence of pretreatment HIV-1 drug resistance in Sweden
Andersson E; Ambikan A; Brannstrom J; Aralaguppe SG; Yilmaz A; Albert J; Neogi U; Sonnerborg A
Article: MOLECULAR & CELLULAR PROTEOMICS. 2021;20:100159
Metabolic Perturbation Associated With COVID-19 Disease Severity and SARS-CoV-2 Replication
Krishnan S; Nordqvist H; Ambikan AT; Gupta S; Sperk M; Svensson-Akusjarvi S; Mikaeloff F; Benfeitas R; Saccon E; Ponnan SM; Rodriguez JE; Nikouyan N; Odeh A; Ahlen G; Asghar M; Sallberg M; Vesterbacka J; Nowak P; Vegvari A; Sonnerborg A; Treutiger CJ; Neogi U
Article: PATHOGENS. 2020;9(5):E320-320
Feasibility of Known RNA Polymerase Inhibitors as Anti-SARS-CoV-2 Drugs
Neogi U; Hill KJ; Ambikan AT; Heng X; Quinn TP; Byrareddy SN; Soennerborg A; Sarafianos SG; Singh K
Article: EMERGING MICROBES & INFECTIONS. 2020;9(1):1748-1760
Dysregulation in Akt/mTOR/HIF-1 signaling identified by proteo-transcriptomics of SARS-CoV-2 infected cells
Appelberg S; Gupta S; Svensson Akusjarvi S; Ambikan AT; Mikaeloff F; Saccon E; Vegvari A; Benfeitas R; Sperk M; Stahlberg M; Krishnan S; Singh K; Penninger JM; Mirazimi A; Neogi U
Article: FRONTIERS IN MICROBIOLOGY. 2019;10:2632
Effects of the Antimicrobial Peptide LL-37 and Innate Effector Mechanisms in Colistin-Resistant Klebsiella pneumoniae With mgrB Insertions
Al-Farsi HM; Al-Adwani S; Ahmed S; Vogt C; Ambikan AT; Leber A; Al-Jardani A; Al-Azri S; Al-Muharmi Z; Toprak MS; Giske CG; Bergman P
Article: METABOLITES. 2019;9(10):E210-210
Plasma Metabolic Signature and Abnormalities in HIV-Infected Individuals on Long-Term Successful Antiretroviral Therapy
Babu H; Sperk M; Ambikan AT; Rachel G; Viswanathan VK; Tripathy SP; Nowak P; Hanna LE; Neogi U
Article: VIRUSES-BASEL. 2019;11(9):E806-806
MiDRMpol: A High-Throughput Multiplexed Amplicon Sequencing Workflow to Quantify HIV-1 Drug Resistance Mutations against Protease, Reverse Transcriptase, and Integrase Inhibitors
Aralaguppe SG; Ambikan AT; Ashokkumar M; Kumar MM; Hanna LE; Amogne W; Sonnerborg A; Neogi U
Article: FRONTIERS IN IMMUNOLOGY. 2019;10:1965
Systemic Inflammation and the Increased Risk of Inflamm-Aging and Age-Associated Diseases in People Living With HIV on Long Term Suppressive Antiretroviral Therapy
Babu H; Ambikan AT; Gabriel EE; Akusjarvi SS; Palaniappan AN; Sundaraj V; Mupanni NR; Sperk M; Cheedarla N; Sridhar R; Tripathy SP; Nowak P; Hanna LE; Neogi U
Article: SCIENTIFIC REPORTS. 2019;9(1):5619
Molecular Characterization and Comparative Genomics of Clinical Hybrid Shiga Toxin-Producing and Enterotoxigenic Escherichia coli (STEC/ETEC) Strains in Sweden
Bai X; Zhang J; Ambikan A; Jernberg C; Ehricht R; Scheutz F; Xiong Y; Matussek A
Article: EBIOMEDICINE. 2018;27:40-50
Transcriptomics and Targeted Proteomics Analysis to Gain Insights Into the Immune-control Mechanisms of HIV-1 Infected Elite Controllers
Zhang W; Ambikan AT; Sperk M; van Domselaar R; Nowak P; Noyan K; Russom A; Sonnerborg A; Neogi U
Article: JOURNAL OF VIROLOGICAL METHODS. 2016;236:98-104
Multiplexed next-generation sequencing and de novo assembly to obtain near full-length HIV-1 genome from plasma virus
Aralaguppe SG; Siddik AB; Manickam A; Ambikan AT; Kumar MM; Fernandes SJ; Amogne W; Bangaruswamy DK; Hanna LE; Sonnerborg A; Neogi U
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Book chapter: ADVANCES IN IMMUNOLOGY, VOL 150. 2024;p. 73-100
System-level integrative omics analysis to identify the virus-host immunometabolic footprint during infection.
Ambikan A; Akusjärvi SS; Sperk M; Neogi U
Preprint: RES SQ. 2023;RES SQ
Proteomic landscape of astrocytes and pericytes infected with HIV/SARS-CoV-2 mono/co-infection, impacting on neurological complications.
Acharya A; Ambikan AT; Thurman M; Malik MR; Dyavar SR; Végvári Á; Neogi U; Byrareddy SN
Doctoral thesis: 2023
Multi-dimensional omics approaches to dissect natural immune control mechanisms associated with RNA virus infections
Tholamplackil Ambikan A

Anställningar

Postdoktor, Laboratoriemedicin, Karolinska Institutet, 2023-2026

Examina och utbildning

Medicine Doktorsexamen, Institutionen för laboratoriemedicin, Karolinska Institutet, 2023

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