Andreas Lundqvist

Andreas Lundqvist

Professor
Telefon: +46852482371
Besöksadress: J6:20 BioClinicum, Akademiska stråket 1, 17164 Solna
Postadress: K7 Onkologi-Patologi, K7 Forskning Lundqvist, 171 77 Stockholm

Om mig

  • Professor, Karolinska Institutet, Institutionen för Onkologi-Patologi, 2023

    Docent, Karolinska Institutet, 2012
    Forskare, National Institutes of Health, 2008
    Postdoktoral utbildning, National Institutes of Health, 2003
    PhD, Karolinska Institutet, 2003

Forskningsbeskrivning

  • Vår forskning fokuserar på att förstå hur immunförsvaret regleras hos patienter med cancer.

Undervisning

  • Genomgått 10 veckor utbildning i pedagogik.
    Kursorganisatör för doktorandkurs i tumörimmunologi (#3110), Karolinska Institutet.

Artiklar

Alla övriga publikationer

Forskningsbidrag

  • The Swedish Childhood Cancer Fund
    1 January 2024 - 31 December 2025
  • Swedish Research Council
    1 January 2023 - 31 December 2026
    Due to their important role to eradicate tumors, natural killer (NK) cells are increasingly utilized in cancer immunotherapy. While the infusion of NK cells shows clinical benefit in hematological malignancies, NK cell therapy has yet to show therapeutic potential in patients with solid tumors. We recently discovered a unique subset of tumor-infiltrating NK cells that exert immune regulatory functions to inhibit anti-tumor T cell responses in solid tumors. Our preliminary results support that these NK cells also play a critical role to orchestrate changes within the tumor microenvironment and to affect epithelial-to-mesenchymal transition (EMT). In this project, we will use in vitro and in vivo models and ex vivo analysis of patient material to address how these NK cells remodel the tumor microenvironment via the crosstalk with myeloid cells, influence the EMT process to promote metastatic dissemination, and interfere with clinical responses to immune checkpoint therapy. In aggregate, we anticipate these studies will support the role of tumor-infiltrating NK cells to suppress local and systemic immune responses and favor tumor progression, metastatic dissemination, and interfere with therapy. Such findings have direct implications to improve therapies based on activating NK cell as well as to implement predictive and prognostic biomarkers in patients with cancer.
  • Barncancerfonden
    1 January 2023 - 31 December 2023
  • The Swedish Cancer Society
    1 January 2022 - 31 December 2024
  • The Cancer Research Funds of Radiumhemmet
    1 January 2022 - 31 December 2024

Anställningar

  • Professor, Onkologi-Patologi, Karolinska Institutet, 2023-

Examina och utbildning

  • MEDICINE DOKTORSEXAMEN, Institutionen för onkologi-patologi, Karolinska Institutet, 2003

Nyheter från KI

Kalenderhändelser från KI