Anders Mutvei

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2023;299(5):104644

An affinity tool for the isolation of endogenous active mTORC1 from various cellular sources.

Ibrahim YH; Pantelios S; Mutvei AP
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2022;298(6):102030

Prolonged deprivation of arginine or leucine induces PI3K/Akt-dependent reactivation of mTORC1.

Buel GR; Dang HQ; Asara JM; Blenis J; Mutvei AP
Article: NATURE METABOLISM. 2022;4(4):435-443

Altered propionate metabolism contributes to tumour progression and aggressiveness.

Gomes AP; Ilter D; Low V; Drapela S; Schild T; Mullarky E; Han J; Elia I; Broekaert D; Rosenzweig A; Nagiec M; Nunes JB; Schaffer BE; Mutvei AP; Asara JM; Cantley LC; Fendt S-M; Blenis J
Article: NATURE. 2020;585(7824):283-287

Age-induced accumulation of methylmalonic acid promotes tumour progression.

Gomes AP; Ilter D; Low V; Endress JE; Fernández-García J; Rosenzweig A; Schild T; Broekaert D; Ahmed A; Planque M; Elia I; Han J; Kinzig C; Mullarky E; Mutvei AP; Asara J; de Cabo R; Cantley LC; Dephoure N; Fendt S-M; Blenis J
Article: NATURE COMMUNICATIONS. 2020;11(1):1416

Rap1-GTPases control mTORC1 activity by coordinating lysosome organization with amino acid availability.

Mutvei AP; Nagiec MJ; Hamann JC; Kim SG; Vincent CT; Blenis J
Article: CANCER CELL. 2019;36(4):402-417.e13

Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization.

Gomes AP; Ilter D; Low V; Rosenzweig A; Shen Z-J; Schild T; Rivas MA; Er EE; McNally DR; Mutvei AP; Han J; Ou Y-H; Cavaliere P; Mullarky E; Nagiec M; Shin S; Yoon S-O; Dephoure N; Massagué J; Melnick AM; Cantley LC; Tyler JK; Blenis J
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2019;116(39):19523-19529

Regulation of GSK3 cellular location by FRAT modulates mTORC1-dependent cell growth and sensitivity to rapamycin.

He L; Fei DL; Nagiec MJ; Mutvei AP; Lamprakis A; Kim BY; Blenis J
Article: ONCOGENE. 2018;37(46):6083-6095

Notch signaling promotes a HIF2α-driven hypoxic response in multiple tumor cell types.

Mutvei AP; Landor SK-J; Fox R; Braune E-B; Tsoi YL; Phoon YP; Sahlgren C; Hartman J; Bergh J; Jin S; Lendahl U
Article: BLOOD. 2018;131(15):1712-1719

Canonical Notch signaling is dispensable for adult steady-state and stress myelo-erythropoiesis.

Duarte S; Woll PS; Buza-Vidas N; Chin DWL; Boukarabila H; Luís TC; Stenson L; Bouriez-Jones T; Ferry H; Mead AJ; Atkinson D; Jin S; Clark S-A; Wu B; Repapi E; Gray N; Taylor S; Mutvei AP; Tsoi YL; Nerlov C; Lendahl U; Jacobsen SEW
Article: NATURE CELL BIOLOGY. 2018;20(3):332-343

Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation.

Zhang H; Freitas D; Kim HS; Fabijanic K; Li Z; Chen H; Mark MT; Molina H; Martin AB; Bojmar L; Fang J; Rampersaud S; Hoshino A; Matei I; Kenific CM; Nakajima M; Mutvei AP; Sansone P; Buehring W; Wang H; Jimenez JP; Cohen-Gould L; Paknejad N; Brendel M; Manova-Todorova K; Magalhães A; Ferreira JA; Osório H; Silva AM; Massey A; Cubillos-Ruiz JR; Galletti G; Giannakakou P; Cuervo AM; Blenis J; Schwartz R; Brady MS; Peinado H; Bromberg J; Matsui H; Reis CA; Lyden D
Article: BMC CANCER. 2015;15:311

Frequency and distribution of Notch mutations in tumor cell lines.

Mutvei AP; Fredlund E; Lendahl U
Article: CELL RESEARCH. 2014;24(4):433-450

PKCζ regulates Notch receptor routing and activity in a Notch signaling-dependent manner.

Sjöqvist M; Antfolk D; Ferraris S; Rraklli V; Haga C; Antila C; Mutvei A; Imanishi SY; Holmberg J; Jin S; Eriksson JE; Lendahl U; Sahlgren C
Article: ONCOGENE. 2013;32(41):4892-4902

Non-canonical Notch signaling activates IL-6/JAK/STAT signaling in breast tumor cells and is controlled by p53 and IKKα/IKKβ.

Jin S; Mutvei AP; Chivukula IV; Andersson ER; Ramsköld D; Sandberg R; Lee KL; Kronqvist P; Mamaeva V; Ostling P; Mpindi J-P; Kallioniemi O; Screpanti I; Poellinger L; Sahlgren C; Lendahl U
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2011;108(46):18814-18819

Hypo- and hyperactivated Notch signaling induce a glycolytic switch through distinct mechanisms.

Landor SK-J; Mutvei AP; Mamaeva V; Jin S; Busk M; Borra R; Grönroos TJ; Kronqvist P; Lendahl U; Sahlgren CM
Article: JOURNAL OF CELL SCIENCE. 2010;123(Pt 17):2931-2942

Control of Notch-ligand endocytosis by ligand-receptor interaction.

Hansson EM; Lanner F; Das D; Mutvei A; Marklund U; Ericson J; Farnebo F; Stumm G; Stenmark H; Andersson ER; Lendahl U

Alla övriga publikationer

Review: NATURE CELL BIOLOGY. 2023;25(9):1254-1264

Balancing lysosome abundance in health and disease.

Mutvei AP; Nagiec MJ; Blenis J
Conference publication: HAEMATOLOGICA. 2017;102:456

BONE MARROW MYELOPOIESIS INDEPENDENTLY OF CANONICAL NOTCH SIGNALING

Duarte S; Woll PS; Natalija B-V; Boukarabila H; Stenson L; Bouriez-Jones T; Ferry H; Mead AJ; Atkinson D; Thongjuea S; Jin S; Clark S-A; Chin D; Lu-S T; Repapi E; Gray N; Taylor S; Mutvei A; Tsoi YL; Nerlov C; Lendahl U; Jacobsen SEW

Anställningar

Senior Forskare, Laboratoriemedicin, Karolinska Institutet, 2023-

Examina och utbildning

Medicine Doktorsexamen, Institutionen för cell- och molekylärbiologi, Karolinska Institutet, 2014

Gästforskning och resestipendier

Postdoctoral research Weill Cornell Medicine / Harvard Medical School, Weill Cornell Medicine, 2014-2019

Artiklar

Alla övriga publikationer

Anställningar

Examina och utbildning

Gästforskning och resestipendier

Nyheter från KI

Kalenderhändelser från KI