Experimental Gynaecology and Cancer Research – Twana Alkasalias research group

Publications

All publications from group members

• Journal article: INTERNATIONAL JOURNAL OF CANCER. 2026;158(10):2530-2536

  The cervico-vaginal DNA methylation WID-qEC test: An epigenetic marker associated with ovarian cancer in the absence of endometrial and cervical cancer

  Redl E; Herzog C; Vavourakis C; Barrett J; Jones A; Evans I; Reisel D; Manchanda R; Bjorge L; Zikan M; Cibula D; Alkasalias T; Radestad AF; Gemzell-Danielsson K; Dubeau L; MacDonald N; Jurkovic D; Pashayan N; Widschwendter M
• Journal article: COMMUNICATIONS MEDICINE. 2026;6(1):150

  Short-term hormonal modulation with mifepristone does not induce oncogenic changes in the endometrium of BRCA1/2 pathogenic variant carriers

  Widschwendter M; Herzog C; Rasul MF; Boggavarapu NR; Redl E; Utjes D; Floter Radestad A; Gemzell-Danielsson K; Alkasalias T
• Journal article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2025;33(11):1451-1461

  Further delineation of defects in MRPS2 causing human OXPHOS deficiency and early developmental abnormalities in zebrafish

  Kandettu A; Yeole M; Sekar H; Garapati K; Kaur N; Anand A; Hegde P; Nair K; Medishetti R; Bhat V; Radhakrishnan P; Mundkur SC; Shrikiran HA; Pandey A; Sevilimedu A; Chakrabarty S; Shukla A
• Journal article: THE LANCET OBSTETRICS GYNAECOLOGY & WOMEN'S HEALTH. 2025;1(2):e146-e148

  The potential role of mifepristone in breast cancer prevention: beyond medical abortion

  Utjés D; Alkasalias T; Cameron ST; Gomperts R; Papaikonomou K; Rådestad AF; Widschwendter M; Gemzell-Danielsson K
• Article: NATURE COMMUNICATIONS. 2025;16(1):8541

  Biomimetic organo-hydrogels reveal the adipose tissue local mechanical anisotropy regulates ovarian cancer invasion

  Gonzalez-Molina J; Nabili P; Marciano D; Abdelnabi S; Gultekin O; Rasul MF; Zhang Y; Nadal C; Chrysanthou A; Alkasalias T; Salehi S; Balkwill F; Lehti K; Gautrot JE
• Journal article: HUMAN REPRODUCTION. 2025;40:deaf097.085

  Spatio-temporal transcriptome of the human proliferative endometrium at a single-cell scale

  Tang Y; Frisendahl C; Nair K; Rao Boggavarapu N; Flam F; Kopp Kallner H; Papaikonomou K; Lalitkumar PG; Gemzell-Danielsson K
• Article: COMMUNICATIONS MEDICINE. 2025;5(1):97

  Epigenetic signatures in surrogate tissues are able to assess cancer risk and indicate the efficacy of preventive measures

  Barrett JE; Herzog CM; Aminzadeh-Gohari S; Redl E; Parveen II; Rothaermel J; Tevini J; Weber DD; Catalano L; Stefan VE; Felder TK; Obrist P; Alkasalias T; Gemzell-Danielsson K; Lang R; Kofler B; Widschwendter M
• Preprint: BIORXIV. 2025

  Blastocoel fluid RNA predicts pregnancy outcome in assisted reproduction

  Frisendahl C; Gemzell-Danielsson K; Nair K; Koch F; Menezes J; Sheikhi M; Dahlgren K; Alnahal W; Lindgren K; Bohlin T; Olofsson JI; Töhönen V; Vafaee F; Lalitkumar PG; Boggavarapu NR; Faridani OR
• Journal article: CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY. 2025;207:104612

  Circular RNAs as key regulators in cancer hallmarks: New progress and therapeutic opportunities

  Hussen BM; Abdullah SR; Jaafar RM; Rasul MF; Aroutiounian R; Harutyunyan T; Liehr T; Samsami M; Taheri M
• Journal article: BIOMED TARGET JOURNAL. 2024;2(2):1-20

  Molecular Mechanisms of Breast Cancer Drug Resistance and CRISPR/Cas9 Strategies to Overcome

  Hussen BM; Ismael BS; Abdulla SS; Jamal NH; Mustafa SA; Najmalddin ZB; Rasul MF
• Article: FRONTIERS IN ENDOCRINOLOGY. 2024;15:1465393

  Hypoxic conditions affect transcriptome of endometrial stromal cells in endometriosis and promote TGFBI axis

  Sarsenova M; Boggavarapu NR; Kask K; Modhukur V; Samuel K; Karro H; Gemzell-Danielsson K; Lalitkumar PGL; Salumets A; Peters M; Lavogina D
• Article: CARTILAGE. 2024;:19476035241302954

  Genomic Effects of Biomechanical Loading in Adolescent Human Growth Plate Cartilage: A Pilot Study

  Zhang Z; Boggavarapu NR; Muhr LSA; Garcia-Serrango A; Aeppli TRJ; Nava TS; Zhao Y; Gutierrez-Farewik EM; Kulachenko A; Savendahl L; Zaman F
• Journal article: MOLECULAR AND CELLULAR PROBES. 2024;78:101986

  Role of microRNAs in neutrophil extracellular trap formation and prevention: Systematic narrative review

  Hussen BM; Rasul MF; Faraj GSH; Abdullah SR; Sulaiman SH; Pourmoshtagh H; Taheri M
• Preprint: BIORXIV. 2024

  The mechanical anisotropy of adipose tissues regulates ovarian cancer invasion

  Gonzalez-Molina J; Nabili P; Marciano D; Abdelnabi S; Gultekin O; Rasul MF; Zhang Y; Nadal C; Chrysanthou A; Alkasalias T; Salehi S; Balkwill F; Lehti K; Gautrot J
• Article: BIOMOLECULES. 2024;14(11):1400

  miR-193b-5p and miR-374b-5p Are Aberrantly Expressed in Endometriosis and Suppress Endometrial Cell Migration In Vitro

  Frisendahl C; Tang Y; Boggavarapu NR; Peters M; Lalitkumar PG; Piltonen TT; Arffman RK; Salumets A; Goette M; Korsching E; Gemzell-Danielsson K
• Article: F AND S SCIENCE. 2024;5(4):306-317

  Transcriptomic profiling of the oocyte-cumulus-granulosa cell complex from estrogen receptor t knockout mice

  Tohonen V; Antonson P; Boggavarapu NR; Ali H; Motaholi LA; Gustafsson J-A; Varshney M; Rodriguez-Wallberg KA; Katayama S; Nalvarte I; Inzunza J
• Journal article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2024;32(10):1291-1298

  De novo variants underlying monogenic syndromes with intellectual disability in a neurodevelopmental cohort from India

  Pande S; Majethia P; Nair K; Rao LP; Mascarenhas S; Kaur N; do Rosario MC; Neethukrishna K; Chaurasia A; Hunakunti B; Jadhav N; Xavier S; Kumar J; Bhat V; Bhavani GS; Narayanan DL; Yatheesha BL; Patil SJ; Nampoothiri S; Kamath N; Aroor S; Bhat RY; Lewis LE; Sharma S; Bajaj S; Sankhyan N; Siddiqui S; Nayak SS; Bielas S; Girisha KM; Shukla A
• Journal article: NON-CODING RNA RESEARCH. 2024;9(3):811-830

  Advanced approaches of the use of circRNAs as a replacement for cancer therapy

  Faraj GSH; Hussen BM; Abdullah SR; Rasul MF; Hajiesmaeili Y; Baniahmad A; Taheri M
• Journal article: PATHOLOGY RESEARCH AND PRACTICE. 2024;260:155402

  Advanced strategies of targeting circular RNAs as therapeutic approaches in colorectal cancer drug resistance

  Hussen BM; Abdullah SR; Mohammed AA; Rasul MF; Hussein AM; Eslami S; Glassy MC; Taheri M
• Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2024;25(14):7590

  Transcriptomic Profile of Breast Tissue of Premenopausal Women Following Treatment with Progesterone Receptor Modulator: Secondary Outcomes of a Randomized Controlled Trial

  Utjes D; Boggavarapu NR; Rasul MF; Koberg I; Zulliger A; Ponandai-Srinivasan S; von Grothusen C; Lalitkumar PG; Papaikonomou K; Alkasalias T; Gemzell-Danielsson K
• Journal article: CURRENT DEVELOPMENTS IN NUTRITION. 2024;8:102552

  Ketogenic Diet Enhances the Anti-Tumor Effect of Mifepristone in a Breast Cancer Mouse Model

  Weber DD; Tevini J; Barrett J; Aminzadeh-Gohari S; Herzog C; Catalano L; Stefan V; Redl E; Alkasalias T; Lang R; Felder TK; Widschwendter M; Kofler B
• Journal article: CELL COMMUNICATION AND SIGNALING. 2024;22(1):329

  CRISPR/Cas9 gene editing: a novel strategy for fighting drug resistance in respiratory disorders

  Hussen BM; Najmadden ZB; Abdullah SR; Rasul MF; Mustafa SA; Ghafouri-Fard S; Taheri M
• Journal article: CLINICAL GENETICS. 2024;105(6):639-654

  Genetic and phenotypic landscape of pediatric-onset epilepsy in 142 Indian families: Counseling and therapeutic implications

  Majethia P; Kaur N; Mascarenhas S; Rao LP; Pande S; Narayanan DL; Bhat V; Nayak SS; Nair KV; Prasannakumar AP; Chaurasia A; Hunakunti B; Jadhav N; Farooqui S; Yeole M; Kothiwale V; Naik R; Bhat V; Aroor S; Lewis L; Purkayastha J; Bhat YR; Praveen BK; Yatheesha BL; Patil SJ; Nampoothiri S; Kamath N; Siddiqui S; Bielas S; Girisha KM; Sharma S; Shukla A
• Article: CANCERS. 2024;16(6):1186

  Natural Killer Cell Dysfunction in Premenopausal BRCA1 Mutation Carriers: A Potential Mechanism for Ovarian Carcinogenesis

  Haran S; Chindera K; Sabry M; Wilkinson N; Arora R; Zubiak A; Bartlett TE; Evans I; Jones A; Reisel D; Herzog C; Alkasalias T; Newman M; Kim J; Radestad AF; Gemzell-Danielsson K; Rosenthal AN; Dubeau L; Lowdell MW; Widschwendter M
• Preprint: MEDRXIV. 2024

  Transcriptomic profile of normal breast tissue post-mifepristone treatment: secondary outcomes of a randomized controlled trial

  Utjés D; Boggavarapu NR; Rasul M; Koberg I; Zulliger A; Ponandai-Srinivasan S; von Grothusen C; Lalitkumar PG; Papaikonomou K; Alkasalias T; Gemzell-Danielsson K
• Journal article: CLINICAL GENETICS. 2024;105(3):302-307

  A novel homozygous variant in PMVK is associated with enhanced IL1β secretion and a hyper-IgD syndrome-like phenotype

  Jairaman A; Badiger VA; Raj S; Nair KV; Balan S; Narayanan DL
• Journal article: NON-CODING RNA RESEARCH. 2024;9(1):236-252

  Role of circular RNAs and gut microbiome in gastrointestinal cancers and therapeutic targets

  Abdullah ST; Abdullah SR; Hussen BM; Younis YM; Rasul MF; Taheri M
• Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2024;25(3):1608

  Global Transcriptomic Analysis of Placentas from Women with Gestational SARS-CoV-2 Infection during the Third Trimester of Pregnancy

  Tang Y; Boggavarapu NR; Aronsson A; Gemzell-Danielsson K; Lalitkumar PG
• Article: HELIYON. 2024;10(1):e23831

  Retinoblastoma vulnerability to combined de novo and salvage pyrimidine ribonucleotide synthesis pharmacologic blockage

  Mollick T; Darekar S; Dalarun B; Plastino F; Zhang J; Fernandez AP; Alkasalias T; Andre H; Lain S
• Journal article: NON-CODING RNA RESEARCH. 2023;8(4):615-632

  Exosomal non-coding RNAs: Blueprint in colorectal cancer metastasis and therapeutic targets

  Hussen BM; Abdullah ST; Abdullah SR; Younis YM; Hidayat HJ; Rasul MF; Mohamadtahr S
• Journal article: MOLECULAR AND CELLULAR PROBES. 2023;72:101929

  Current landscape of miRNAs and TGF-β signaling in lung cancer progression and therapeutic targets

  Hussen BM; Saleem SJ; Abdullah SR; Mohamadtahr S; Hidayat HJ; Rasul MF; Taheri M; Kiani A
• Journal article: NON-CODING RNA RESEARCH. 2023;8(4):645-660

  New insights of miRNA molecular mechanisms in breast cancer brain metastasis and therapeutic targets

  Hussen BM; Abdullah KH; Abdullah SR; Majeed NM; Mohamadtahr S; Rasul MF; Dong P; Taheri M; Samsami M
• Journal article: CLINICAL DYSMORPHOLOGY. 2023;32(4):162-167

  Delineation of molecular characteristics of congenital myasthenic syndromes in Indian families and review of literature

  Mishra S; Nair KV; Shukla A
• Journal article: CYTOKINE. 2023;170:156351

  Role of long non-coding RNAs and TGF-ß signaling in the regulation of breast cancer pathogenesis and therapeutic targets

  Hussen BM; Hidayat HJ; Abdullah SR; Mohamadtahr S; Rasul MF; Samsami M; Taheri M
• Journal article: MILITARY MEDICAL RESEARCH. 2023;10(1):32

  Targeting miRNA by CRISPR/Cas in cancer: advantages and challenges

  Hussen BM; Rasul MF; Abdullah SR; Hidayat HJ; Faraj GSH; Ali FA; Salihi A; Baniahmad A; Ghafouri-Fard S; Rahman M; Glassy MCC; Branicki W; Taheri M
• Journal article: PATHOLOGY RESEARCH AND PRACTICE. 2023;247:154549

  A review on the role of LINC00472 in malignant and non-malignant disorders

  Ghafouri-Fard S; Askari A; Hussen BM; Rasul MF; Taheri M; Ayatollahi SA
• Journal article: CELL COMMUNICATION AND SIGNALING. 2023;21(1):79

  MiRNA-93: a novel signature in human disorders and drug resistance

  Hussen BM; Abdullah SR; Rasul MF; Jawhar ZH; Faraj GSH; Kiani A; Taheri M
• Article: FRONTIERS IN ENDOCRINOLOGY. 2023;14:1026168

  Bromocriptine inhibits proliferation in the endometrium from women with adenomyosis

  Tang Y; Ponandai-srinivasan S; Frisendahl C; Andersson JK; Pavone D; Stewart EA; Lalitkumar PGL; Korsching E; Bogavarappu NR; Gemzell-Danielsson K
• Journal article: PATHOLOGY RESEARCH AND PRACTICE. 2023;243:154351

  A review on the role of LINC00173 in human cancers

  Ghafouri-Fard S; Safarzadeh A; Hussen BM; Rasul MF; Taheri M; Dilmaghani NA
• Journal article: FRONTIERS IN GENETICS. 2023;14:1126944

  Exosomal circular RNAs: New player in breast cancer progression and therapeutic targets

  Hussen BM; Mohamadtahr S; Abdullah SR; Hidayat HJ; Rasul MF; Hama Faraj GS; Ghafouri-Fard S; Taheri M; Khayamzadeh M; Jamali E
• Journal article: INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. 2023;225:1038-1048

  Recent insights into the roles of circular RNAs in human brain development and neurologic diseases

  Najafi S; Zarch SMA; Majidpoor J; Pordel S; Aghamiri S; Rasul MF; Asemani Y; Vakili O; Mohammadi V; Movahedpour A; Arghiani N
• Journal article: PATHOLOGY RESEARCH AND PRACTICE. 2023;241:154274

  A review on the role of LINC00152 in different disorders

  Ghafouri-Fard S; Askari A; Hussen BM; Rasul MF; Taheri M; Kiani A
• Journal article: PATHOLOGY RESEARCH AND PRACTICE. 2023;241:154270

  Expression of Treg-associated lncRNAs in breast cancer

  Moallemi-Rad L; Ghorbani A; Dadyar M; Hussen BM; Rasul MF; Eslami S; Taheri M; Jamali E; Ghafouri-Fard S
• Journal article: FRONTIERS IN MOLECULAR BIOSCIENCES. 2022;9:1077968

  A review on the role of miR-671 in human disorders

  Ghafouri-Fard S; Askari A; Hussen BM; Rasul MF; Hatamian S; Taheri M; Kiani A
• Journal article: CANCER CELL INTERNATIONAL. 2022;22(1):378

  Exosomal circular RNA: a signature for lung cancer progression

  Hussen BM; Abdullah SR; Faraj GSH; Rasul MF; Salihi A; Ghafouri-Fard S; Taheri M; Mokhtari M
• Corrigendum: CELL DEATH DISCOVERY. 2022;8(1):472

  Proof-of-principle studies on a strategy to enhance nucleotide imbalance specifically in cancer cells (vol 15, pg 548, 2022)

  Alkasalias T; Zhang J; Madapura H; Dalarun B; Reina OB; Lewensohn R; Viktorsson K; Salihi A; Darekar S; Lain S
• Article: CELL DEATH DISCOVERY. 2022;8(1):464

  Proof-of-principle studies on a strategy to enhance nucleotide imbalance specifically in cancer cells

  Alkasalias T; Zhang J; Madapura H; Dalarun B; Reina OB; Lewensohn R; Viktorsson K; Salihi A; Darekar S; Lain S
• Journal article: CANCER CELL INTERNATIONAL. 2022;22(1):323

  Strategies to overcome the main challenges of the use of exosomes as drug carrier for cancer therapy

  Hussen BM; Faraj GSH; Rasul MF; Hidayat HJ; Salihi A; Baniahmad A; Taheri M; Ghafouri-Frad S
• Preprint: RESEARCH SQUARE. 2022

  Proof-of-principle studies on a strategy to enhance nucleotide imbalance specifically in cancer cells

  Lain S; Alkasalias T; Zhang J; Madapura H; Dalaroun B; Reina OB; Lewensohn R; Viktorsson K; Salihi A; Darekar S
• Corrigendum: GENOME MEDICINE. 2022;14(1):76

  Antiprogestins reduce epigenetic field cancerization in breast tissue of young healthy women (vol 14, 64, 2022)

  Bartlett TE; Evans I; Jones A; Barrett JE; Haran S; Reisel D; Papaikonomou K; Jones L; Herzog C; Pashayan N; Simoes BM; Clarke RB; Evans DG; Ghezelayagh TS; Ponandai-Srinivasan S; Boggavarapu NR; Lalitkumar PG; Howell SJ; Risques RA; Radestad AF; Dubeau L; Gemzell-Danielsson K; Widschwendter M
• Review: MOLECULAR MEDICINE REPORTS. 2022;26(1):233

  Gasotransmitters in the tumor microenvironment: Impacts on cancer chemotherapy

  Salihi A; Al-Naqshabandi MA; Khudhur ZO; Housein Z; Hama HA; Abdullah RM; Hussen BM; Alkasalias T
• Article: GENOME MEDICINE. 2022;14(1):64

  Antiprogestins reduce epigenetic field cancerization in breast tissue of young healthy women

  Bartlett TE; Evans I; Jones A; Barrett JE; Haran S; Reisel D; Papaikonomou K; Jones L; Herzog C; Pashayan N; Simoes BM; Clarke RB; Evans DG; Ghezelayagh TS; Ponandai-Srinivasan S; Boggavarapu NR; Lalitkumar PG; Howell SJ; Risques RA; Radestad AF; Dubeau L; Gemzell-Danielsson K; Widschwendter M
• Journal article: INDIAN JOURNAL OF PEDIATRICS. 2022;89(6):594-596

  Late Onset Subacute Profound Biotinidase Deficiency Caused by a Novel Homozygous Variant c.466-3T>G in the BTD Gene

  Mohite K; Nair KV; Sapare A; Bhat V; Shukla A; Kekatpure M; Patil SJ
• Journal article: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 2022;1510(1):18-35

  Strategies to overcome the side effects of chimeric antigen receptor T cell therapy

  Mirzaee Godarzee M; Mahmud Hussen B; Razmara E; Hakak-Zargar B; Mohajerani F; Dabiri H; Fatih Rasul M; Ghazimoradi MH; Babashah S; Sadeghizadeh M
• Article: HUMAN REPRODUCTION. 2022;37(4):734-746

  Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure

  von Grothusen C; Frisendahl C; Modhukur V; Lalitkumar PG; Peters M; Faridani OR; Salumets A; Boggavarapu NR; Gemzell-Danielsson K
• Journal article: MOLECULAR CANCER. 2022;21(1):64

  Strategies to overcome the main challenges of the use of CRISPR/Cas9 as a replacement for cancer therapy

  Rasul MF; Hussen BM; Salihi A; Ismael BS; Jalal PJ; Zanichelli A; Jamali E; Baniahmad A; Ghafouri-Fard S; Basiri A; Taheri M
• Journal article: PATHOLOGY RESEARCH AND PRACTICE. 2022;230:153760

  The emerging roles of NGS in clinical oncology and personalized medicine

  Hussen BM; Abdullah ST; Salihi A; Sabir DK; Sidiq KR; Rasul MF; Hidayat HJ; Ghafouri-Fard S; Taheri M; Jamali E
• Journal article: PATHOLOGY RESEARCH AND PRACTICE. 2022;230:153764

  Signaling pathways modulated by miRNAs in breast cancer angiogenesis and new therapeutics

  Hussen BM; Salihi A; Abdullah ST; Rasul MF; Hidayat HJ; Hajiesmaeili M; Ghafouri-Fard S
• Article: JOURNAL OF NEUROINFLAMMATION. 2022;19(1):20

  An overlooked subset of Cx3cr1^wt/wt microglia in the Cx3cr1^{CreER-Eyfp/wt} mouse has a repopulation advantage over Cx3cr1^{CreER-Eyfp/wt} microglia following microglial depletion

  Zhou K; Han J; Lund H; Boggavarapu NR; Lauschke VM; Goto S; Cheng H; Wang Y; Tachi A; Xie C; Zhu K; Sun Y; Osman AM; Liang D; Han W; Gemzell-Danielsson K; Betsholtz C; Zhang X-M; Zhu C; Enge M; Joseph B; Harris RA; Blomgren K
• Article: LIFE-BASEL. 2021;11(12):1391

  Coupling miR/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity

  Nikolova M; Naydenov M; Glogovitis I; Apostolov A; Saare M; Boggavarapu N; Salumets A; Baev V; Yahubyan G
• Journal article: GENE REPORTS. 2021;25:101409

  Comparative study of SARS-CoV-2 antibody titers between male and female COVID-19 patients living in Kurdistan region of Iraq

  Ishaq SE; Abdulqadir SZ; Khudhur ZO; Omar SA; Qadir MK; Awla HK; Rasul MF; Bapir AA; Zanichelli A; Mansoor MK; Kaleem M; Rizwan MA; Smail SW; Babaei E
• Journal article: CLINICAL GENETICS. 2021;100(5):542-550

  Clinical and genetic spectrum of 104 Indian families with central nervous system white matter abnormalities

  Kaur P; do Rosario MC; Hebbar M; Sharma S; Kausthubham N; Nair K; Shrikiran A; Bhat YR; Lewis LES; Nampoothiri S; Patil SJ; Suresh N; Bijarnia Mahay S; Dua Puri R; Pai S; Kaur A; Rakshith KC; Kamath N; Bajaj S; Kumble A; Shetty R; Shenoy R; Kamate M; Shah H; Muranjan MN; Yatheesha BL; Avabratha KS; Subramaniam G; Kadavigere R; Bielas S; Girisha KM; Shukla A
• Journal article: MULTIPLE SCLEROSIS AND RELATED DISORDERS. 2021;56:103228

  The role of oxidative stress and haematological parameters in relapsing-remitting multiple sclerosis in Kurdish population

  Rasoul AA; Khudhur ZO; Hamad MS; Ismaeal YS; Smail SW; Rasul MF; Mohammad KA; Bapir AA; Omar SA; Qadir MK; Rajab MF; Salihi A; Kaleem M; Rizwan MA; Qureshi AS; Iqbal ZM; Qudratullah
• Journal article: FRONTIERS IN MOLECULAR BIOSCIENCES. 2021;8:764025

  MicroRNAs: Important Players in Breast Cancer Angiogenesis and Therapeutic Targets

  Hussen BM; Abdullah ST; Rasul MF; Salihi A; Ghafouri-Fard S; Hidayat HJ; Taheri M
• Journal article: ARABIAN JOURNAL OF CHEMISTRY. 2021;14(10):103353

  Exploring the interaction of quercetin-3-O-sophoroside with SARS-CoV-2 main proteins by theoretical studies: A probable prelude to control some variants of coronavirus including Delta

  Khan S; Hussain A; Vahdani Y; Kooshki H; Hussen BM; Haghighat S; Rasul MF; Hidayat HJ; Hasan A; Edis Z; Bloukh SH; Kasravi S; Babadaei MMN; Sharifi M; Bai Q; Liu J; Hu B; Akhtari K; Falahati M
• Article: REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY. 2021;19(1):115

  Trophoblast derived extracellular vesicles specifically alter the transcriptome of endometrial cells and may constitute a critical component of embryo-maternal communication

  Godakumara K; Ord J; Lattekivi F; Dissanayake K; Viil J; Boggavarapu NR; Faridani OR; Jaager K; Velthut-Meikas A; Jaakma U; Salumets A; Fazeli A
• Article: JOURNAL OF PERSONALIZED MEDICINE. 2021;11(6):448

  Stromal Heterogeneity in the Human Proliferative Endometrium-A Single-Cell RNA Sequencing Study

  Queckborner S; von Grothusen C; Boggavarapu NR; Francis RM; Davies LC; Gemzell-Danielsson K
• Review: FOOD AND CHEMICAL TOXICOLOGY. 2021;150:112087

  Inflammation, immunity and potential target therapy of SARS-COV-2: A total scale analysis review

  Smail SW; Saeed M; Alkasalias T; Khudhur ZO; Younus DA; Rajab MF; Abdulahad WH; Hussain HI; Niaz K; Safdar M
• Article: HUMAN REPRODUCTION. 2020;35(10):2280-2293

  Syndecan-I modulates the invasive potential of endometrioma via TGF-β signalling in a subgroup of women with endometriosis

  Ponandai-Srinivasan S; Saare M; Boggavarapu NR; Frisendahl C; Ehrstrom S; Riethmueller C; Garcia-Uribe PA; Rettkowski J; Iyengar A; Salumets A; Lalitkumar PGL; Goette M; Gemzell-Danielsson K
• Article: EMBO MOLECULAR MEDICINE. 2020;12(4):e11177

  Adaptive RSK-EphA2-GPRC5A signaling switch triggers chemotherapy resistance in ovarian cancer

  Moyano-Galceran L; Pietila EA; Turunen SP; Corvigno S; Hjerpe E; Bulanova D; Joneborg U; Alkasalias T; Miki Y; Yashiro M; Chernenko A; Jukonen J; Singh M; Dahlstrand H; Carlson JW; Lehti K
• Journal article: CLINICAL CANCER RESEARCH. 2019;25(22_Supplement):gmm-041-gmm-041

  Abstract GMM-041: OVARIAN CANCER CELLS INDUCE A FEEDBACK RESPONSE TO PLATINUM-BASED CHEMOTHERAPY BY ACTIVATING AN ONCOGENIC RSK-EPHA2-GPRC5A SIGNALING SWITCH

  Moyano-Galceran L; Turunen SP; Pietilä E; Alkasalias T; Corvigno S; Hjerpe E; Joneborg U; Bulanova D; Eriksson M; Dahlstrand H; Carlson J; Lehti K
• Conference publication: CLINICAL CANCER RESEARCH. 2019;25(22):104

  OVARIAN CANCER CELLS INDUCE A FEEDBACK RESPONSE TO PLATINUM-BASED CHEMOTHERAPY BY ACTIVATING AN ONCOGENIC RSK-EPHA2-GPRC5A SIGNALING SWITCH

  Moyano-Galceran L; Turunen SP; Pietila E; Alkasalias T; Corvigno S; Hjerpe E; Joneborg U; Bulanova D; Eriksson M; Dahlstrand H; Carlson J; Lehti K
• Article: HUMAN REPRODUCTION. 2018;33(10):1889-1897

  Effect of mifepristone on the transcriptomic signature of endometrial receptivity

  von Grothusen C; Lalitkumar PG; Ruiz-Alonso M; Boggavarapu NR; Navarro R; Miravet-Valenciano J; Gemzell-Danielsson K; Simon C
• Article: CONTRACEPTION. 2018;98(4):317-322

  Molecular characterization of PRM-associated endometrial changes, PAEC, following mifepristone treatment

  Berger C; Boggavarapu N; Norlin E; Queckborner S; Hornaeus K; Falk A; Engman M; Ramstrom M; Lalitkumar PGL; Gemzell-Danielsson K
• Review: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2018;19(5):E1532-1532

  Fibroblasts in the Tumor Microenvironment: Shield or Spear?

  Alkasalias T; Moyano-Galceran L; Arsenian-Henriksson M; Lehti K
• Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2018;22(1):163-172

  Prokineticin 1 is up-regulated by insulin in decidualizing human endometrial stromal cells

  Ujvari D; Jakson I; Oldmark C; Attarha S; Alkasalias T; Salamon D; Gidlof S; Hirschberg AL
• Doctoral thesis: 2017

  Tumor microenvironment : the paradoxical action of fibroblasts

  Alkasalias THA
• Doctoral thesis: 2017

  Molecular and functional studies on human embryo implantation : targets for infertility and fertility regulation

  Nageswara BR
• Article: CLINICAL CANCER RESEARCH. 2017;23(16):4769-4779

  A Zebrafish Model Discovers a Novel Mechanism of Stromal Fibroblast-Mediated Cancer Metastasis

  Liu C; Zhang Y; Lim S; Hosaka K; Yang Y; Pavlova T; Alkasalias T; Hartman J; Jensen L; Xing X; Wang X; Lu Y; Nie G; Cao Y
• Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2017;114(8):E1413-E1421

  RhoA knockout fibroblasts lose tumor-inhibitory capacity in vitro and promote tumor growth in vivo

  Alkasalias T; Alexeyenko A; Hennig K; Danielsson F; Lebbink RJ; Fielden M; Turunen SP; Lehti K; Kashuba V; Madapura HS; Bozoky B; Lundberg E; Balland M; Guven H; Klein G; Gad AKB; Pavlova T
• Article: SCIENTIFIC REPORTS. 2016;6:33811

  expression profiling of receptive endometrium reveals progesterone regulated ENPP3 is differentially expressed and secreted in glycosylated form

  Boggavarapu NR; Lalitkumar S; Joshua V; Kasvandik S; Salumets A; Lalitkumar PG; Gemzell-Danielsson K
• Article: CONTRACEPTION. 2016;94(2):143-151

  Effects of low doses of mifepristone on human embryo implantation process in a three-dimensional human endometrial in vitro co-culture system

  Boggavarapu NR; Berger C; von Grothusen C; Menezes J; Gemzell-Danielsson K; Lalitkumar PGL
• Article: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH. 2015;34(1):62

  Confrontation of fibroblasts with cancer cells in vitro: gene network analysis of transcriptome changes and differential capacity to inhibit tumor growth

  Alexeyenko A; Alkasalias T; Pavlova T; Szekely L; Kashuba V; Rundqvist H; Wiklund P; Egevad L; Csermely P; Korcsmaros T; Guven H; Klein G
• Article: HUMAN REPRODUCTION. 2015;30(4):800-811

  Effects of ulipristal acetate on human embryo attachment and endometrial cell gene expression in an in vitro co-culture system

  Berger C; Boggavarapu NR; Menezes J; Lalitkumar PGL; Gemzell-Danielsson K
• Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2014;111(48):17188-17193

  Inhibition of tumor cell proliferation and motility by fibroblasts is both contact and soluble factor dependent

  Alkasalias T; Flaberg E; Kashuba V; Alexeyenko A; Pavlova T; Savchenko A; Szekely L; Klein G; Guven H
• Review: AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY. 2014;72(2):148-157

  Recent Advances in Understanding Endometrial Receptivity: Molecular Basis and Clinical Applications

  von Grothusen C; Lalitkumar S; Boggavarapu NR; Gemzell-Danielsson K; Lalitkumar PG
• Article: FERTILITY AND STERILITY. 2013;100(4):1160-1169

  Polyethylene glycated leukemia inhibitory factor antagonist inhibits human blastocyst implantation and triggers apoptosis by down-regulating embryonic AKT

  Lalitkumar S; Boggavarapu NR; Menezes J; Dimitriadis E; Zhang J-G; Nicola NA; Gemzell-Danielsson K; Lalitkumar LPG
• Show more

Staff and contact

Group leader

• 

  Twana Alkasalias

  Assistant Professor

  E-mail twana.alkasalias@ki.se

All members of the group

• 

  Nageswara Rao Boggavarapu

  Assistant Professor

  E-mail nageswara.boggavarapu@ki.se
• 

  Karthik Vijay Nair

  Phd Student

  E-mail karthik.nair@ki.se
• 

  Mohammed Fatih Rasul

  Phd Student

  E-mail mohammed.rasul@ki.se