Swedish Mammography Cohort - Clinical (SMC-C)

Recruitment 1

From 2003 through 2009, 8,311 women under age 85 and living in the town of Uppsala received a diet, lifestyle, and physical activity questionnaire with an invitation to participate in a health examination. Sixty-five percent of the invited participants completed the questionnaire and 61% participated in the health examination which included weight, height, waist, hip, and blood pressure measurements, and a dual energy X-ray absorptiometry (DEXA) scan. Samples of fasting blood, urine, and adipose tissue were also collected at the health exam.

A subset of these women completed an additional FFQ and physical activity questionnaire and wore a physical activity monitor and completed a 7-day activity record. A second subset of women completed a questionnaire on sun exposure in conjunction with a blood sample collected during winter and summer months.

A second health examination, biological sample collection, and diet and lifestyle questionnaire, is planned for this clinical subcohort in November 2013.

Recruitment 2

From March 2012 to March 2013, 1,030 women in the SMC over age 85 and living in Uppsala County received an invitation letter to participate in a validated cognitive test phone interview, complete a FFQ, and receive a home health examination. The home health examination included weight, height, waist, hip, and blood pressure measurements, blood, urine, adipose tissue, and fecal sample collection, a physical function test, and the Mini Mental State Examination (MMSE).

Principal Investigators

Prof Alicja Wolk and Prof Karl Michaëlsson