Prenatal metabolic exposure and risk of subsequent metabolic and psychiatric disorders

The purpose of our research is to find out if, and if so, to what extent the mother's obesity, diabetes, polycystic ovary syndrome, hypertension and related metabolic conditions are associated with the child's later metabolic and mental health, and if birth factors mediate or modify these associations. We study also possible protective factors. We do these studies in data from nation-wide registries.

Team-leader: Catharina Lavebratt

Co-workers in the Translational Psychiatry Group:

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Mika Gissler

Principal Researcher
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Ida Nilsson

Senior Research Specialist

Publications

Association of maternal polycystic ovary syndrome and diabetes with preterm birth and offspring birth size: a population-based cohort study.
Chen X, Gissler M, Lavebratt C
Hum Reprod 2022 Mar;():

Association of Preeclampsia and Perinatal Complications With Offspring Neurodevelopmental and Psychiatric Disorders.
Kong L, Chen X, Liang Y, Forsell Y, Gissler M, Lavebratt C
JAMA Netw Open 2022 01;5(1):e2145719

Association of polycystic ovary syndrome or anovulatory infertility with offspring psychiatric and mild neurodevelopmental disorders: a Finnish population-based cohort study.
Chen X, Kong L, Piltonen TT, Gissler M, Lavebratt C
Hum Reprod 2020 10;35(10):2336-2347

Relationship of prenatal maternal obesity and diabetes to offspring neurodevelopmental and psychiatric disorders: a narrative review.
Kong L, Chen X, Gissler M, Lavebratt C
Int J Obes (Lond) 2020 10;44(10):1981-2000

Associations of Different Types of Maternal Diabetes and Body Mass Index With Offspring Psychiatric Disorders.
Kong L, Nilsson IAK, Brismar K, Gissler M, Lavebratt C
JAMA Netw Open 2020 02;3(2):e1920787

Associations of Maternal Diabetes and Body Mass Index With Offspring Birth Weight and Prematurity.
Kong L, Nilsson IAK, Gissler M, Lavebratt C
JAMA Pediatr 2019 04;173(4):371-378

The Risk of Offspring Psychiatric Disorders in the Setting of Maternal Obesity and Diabetes.
Kong L, Norstedt G, Schalling M, Gissler M, Lavebratt C
Pediatrics 2018 09;142(3):

CL
Content reviewer:
Lilian Pagrot
31-05-2023