Ida Nilsson
Senior Research Specialist | Docent
E-mail: ida.nilsson@ki.se
Visiting address: CMM, Karolinska universitetssjukhuset L8:00, 17176 Stockholm
Postal address: K1 Molekylär medicin och kirurgi, K1 MMK Translationell psykiatri, 171 76 Stockholm
About me
- Associate Professor in Neuroscience and responsible for Spatial Biology at KIGene
MSc in Nutrition, Stockholm University, 2004
PhD in Medical Science, Karolinska Instituet, 2010
Postdoctoral Training, Lab of Dir. Vincent Prévot, INSERM, Lille (FR), 2011
NARSAD Young Investigator 2013-2014
Research
- The neurobiology of anorexia nervosa
The memory of us in my original family celebrating when my older sister, several years after her weight recovery from anorexia nervosa (AN), finally
felt hunger again has been my guiding star and motivator during my years in research on the neurobiology of AN. How come that individuals with AN stay in negative energy balance, severely emaciated and starved, commonly for years, despite that the human body and brain in order to ensure our survival, have developed intricate systems to prevent exactly this. At the same time others struggle to lose weight their whole life. Based on our own and others previous results we propose that genetic vulnerability to anorexia nervosa (AN) combined with environmental triggers of dieting/food restriction, induce changes in arcuate nucleus of the hypothalamus (Arc) neurons, and their communication with surrounding microglia, resulting in a paradoxical response to negative energy balance.
We utilise clinical samples, as well as preclinical- and stem cell based models, and medical registries, in order to define the neuronal circuitries
and molecular mechanisms involved in the negative energy balance of AN. We believe that we by defining these mechanisms can contribute to the
development of pharmaceuticals supporting renourishment and weight gain in the very critical initial phase of treatment of individuals with AN.
Articles
- Article: CLINICAL NUTRITION ESPEN. 2024;63:74-83
- Article: BIOLOGICAL PSYCHIATRY GLOBAL OPEN SCIENCE. 2024;4(5):100332
- Journal article: NEUROSCIENCE APPLIED. 2024;3:104030
- Article: INTERNATIONAL JOURNAL OF EATING DISORDERS. 2023;56(12):2232-2249
- Journal article: NEUROSCIENCE APPLIED. 2023;2:103444
- Article: NUTRIENTS. 2022;14(24):5247
- Article: MOLECULAR PSYCHIATRY. 2021;26(11):6820-6832
- Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2021;49:1-10
- Journal article: INTERNATIONAL JOURNAL OF EATING DISORDERS. 2020;53(12):2095
- Article: BRAIN, BEHAVIOR, AND IMMUNITY. 2020;88:718-724
- Article: INTERNATIONAL JOURNAL OF EATING DISORDERS. 2020;53(5):432-446
- Article: JAMA NETWORK OPEN. 2020;3(2):e1920787
- Article: NEUROENDOCRINOLOGY. 2020;110(6):552-562
- Article: BIOLOGICAL PSYCHIATRY. 2019;86(8):577-586
- Article: TRANSLATIONAL PSYCHIATRY. 2019;9(1):180
- Article: MOLECULAR NEUROBIOLOGY. 2019;56(7):5146-5156
- Article: JAMA PEDIATRICS. 2019;173(4):371-378
- Journal article: NUTRITION CLINIQUE ET METABOLISME. 2019;33(1):7-8
- Article: AMERICAN JOURNAL OF PSYCHIATRY. 2017;174(9):850-858
- Article: SCIENTIFIC REPORTS. 2017;7(1):7906
- Article: JOURNAL OF ENDOCRINOLOGY. 2017;233(1):15-24
- Article: AMERICAN JOURNAL OF PHYSIOLOGY - ENDOCRINOLOGY AND METABOLISM. 2015;309(4):E418-E427
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2011;108(44):18108-18113
- Article: GLIA. 2011;59(1):45-57
- Article: JOURNAL OF COMPARATIVE NEUROLOGY. 2008;507(1):1128-1140
- Article: PHYSIOLOGY AND BEHAVIOR. 2007;92(1-2):278-282
- Article: BIOLOGICAL PSYCHIATRY. 2006;60(8):799-802
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2005;102(41):14865-14870
- Article: DEVELOPMENTAL BRAIN RESEARCH. 2005;155(2):147-154
- Show more
All other publications
- Preprint: RESEARCH SQUARE. 2022
- Corrigendum: MOLECULAR PSYCHIATRY. 2022;27(3):1855
- Book chapter: ANIMAL MODELS OF EATING DISORDERS: NEUROMETHODS. 2021;p. 297-317
- Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2020;31:S7
- Review: FRONTIERS IN NEUROSCIENCE. 2019;13:59
- Preprint: BIORXIV. 2018
- Review: EUROPEAN EATING DISORDERS REVIEW. 2017;25(6):432-450
- Review: VITAMINS AND HORMONES. 2013;92:27-60
- Meeting abstract: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2011;21:S10-S11
- Thesis / dissertation: 2010
- Published conference paper: NUTRITION. 2008;24(9):860-868
Employments
- Senior Research Specialist, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2022-
Degrees and Education
- Docent, Karolinska Institutet, 2021
- Degree Of Doctor Of Philosophy, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2010