Prenatal metabolic exposure and risk of subsequent metabolic and psychiatric disorders
The purpose of our research is to find out if, and if so, to what extent the mother's obesity, diabetes, polycystic ovary syndrome, hypertension and related metabolic conditions are associated with the child's later metabolic and mental health, and if birth factors mediate or modify these associations. We study also possible protective factors. We do these studies in data from nation-wide registries.
Team-leader: Catharina Lavebratt
Catharina Lavebratt
Principal ResearcherCo-workers in the Translational Psychiatry Group:
Mika Gissler
Principal ResearcherIda Nilsson
Principal ResearcherPublications
Prenatal exposure to maternal hypertension and higher body mass index and risks of neurodevelopmental and psychiatric disorders during childhood. Nivins S, Kumar P, Gissler, M, Chen X, Lavebratt C. AOGS Accepted
Maternal Eating Disorders, Body Mass Index, and Offspring Psychiatric Diagnoses.
Nilsson IAK, Ozsvar J, Gissler M, Lavebratt C
JAMA Netw Open 2024 Oct;7(10):e2440517
Association of preterm birth and birth size status with neurodevelopmental and psychiatric disorders in spontaneous births.
Kong L, Nivins S, Chen X, Liang Y, Gissler M, Lavebratt C
Eur Child Adolesc Psychiatry 2024 Jun;():
Birth outcomes in mothers with hypertensive disorders and polycystic ovary syndrome: a population-based cohort study.
Chen X, Gissler M, Lavebratt C
Hum Reprod Open 2023 ;2023(4):hoad048
Exposures during pregnancy and at birth are associated with the risk of offspring eating disorders.
Ozsvar J, Gissler M, Lavebratt C, Nilsson IAK
Int J Eat Disord 2023 Dec;56(12):2232-2249
Association of maternal polycystic ovary syndrome or anovulatory infertility with obesity and diabetes in offspring: a population-based cohort study.
Chen X, Koivuaho E, Piltonen TT, Gissler M, Lavebratt C
Hum Reprod 2021 Jul;36(8):2345-2357
Association of maternal polycystic ovary syndrome and diabetes with preterm birth and offspring birth size: a population-based cohort study.
Chen X, Gissler M, Lavebratt C
Hum Reprod 2022 Mar;():
Association of Preeclampsia and Perinatal Complications With Offspring Neurodevelopmental and Psychiatric Disorders.
Kong L, Chen X, Liang Y, Forsell Y, Gissler M, Lavebratt C
JAMA Netw Open 2022 01;5(1):e2145719
Association of polycystic ovary syndrome or anovulatory infertility with offspring psychiatric and mild neurodevelopmental disorders: a Finnish population-based cohort study.
Chen X, Kong L, Piltonen TT, Gissler M, Lavebratt C
Hum Reprod 2020 10;35(10):2336-2347
Relationship of prenatal maternal obesity and diabetes to offspring neurodevelopmental and psychiatric disorders: a narrative review.
Kong L, Chen X, Gissler M, Lavebratt C
Int J Obes (Lond) 2020 10;44(10):1981-2000
Associations of Different Types of Maternal Diabetes and Body Mass Index With Offspring Psychiatric Disorders.
Kong L, Nilsson IAK, Brismar K, Gissler M, Lavebratt C
JAMA Netw Open 2020 02;3(2):e1920787
Associations of Maternal Diabetes and Body Mass Index With Offspring Birth Weight and Prematurity.
Kong L, Nilsson IAK, Gissler M, Lavebratt C
JAMA Pediatr 2019 04;173(4):371-378
The Risk of Offspring Psychiatric Disorders in the Setting of Maternal Obesity and Diabetes.
Kong L, Norstedt G, Schalling M, Gissler M, Lavebratt C
Pediatrics 2018 09;142(3):