Project: Gender differences in carcinogenesis

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In this project we investigate sex differences in response to carcinogens. A main objective is to identify chemicals exhibiting sexual dimorphism in their response. Another objective is to identify mode of action for these chemicals. Of special interest is oxidative stress and male susceptibility to carcinogens.

Contact person

Head of department

Ulla Stenius

Phone: +46-(0)8-524 878 72
Organizational unit: Biochemical toxicology
E-mail: Ulla.Stenius@ki.se

Financing

  • The Swedish research Council for Environment
  • Agricultural Sciences and Spatial Planning (FORMAS)

Publications

Gender differences in cancer susceptibility: role of oxidative stress.
Ali I, Högberg J, Hsieh J, Auerbach S, Korhonen A, Stenius U, et al
Carcinogenesis 2016 Oct;37(10):985-992

Exocrine pancreatic carcinogenesis and autotaxin expression.
Kadekar S, Silins I, Korhonen A, Dreij K, Al-Anati L, Högberg J, et al
PLoS ONE 2012 ;7(8):e43209

Gender differences in chemical carcinogenesis in National Toxicology Program 2-year bioassays.
Kadekar S, Peddada S, Silins I, French J, Högberg J, Stenius U
Toxicol Pathol 2012 Dec;40(8):1160-8