Zhichao Zhou

Publikationer
Forskningsbidrag
CV
Populärvetenskap och samverkan

Artiklar

Article: CLINICAL SCIENCE. 2024;138(15):975-985

Differences in endothelial function between patients with Type 1 and Type 2 diabetes: effects of red blood cells and arginase.

Tengbom J; Kontidou E; Collado A; Yang J; Alvarsson M; Brinck J; Rössner S; Zhou Z; Pernow J; Mahdi A
Journal article: CARDIOVASCULAR RESEARCH. 2024;120:cvae088.035

Red blood cell-derived extracellular vesicles from type 2 diabetes patients induce endothelial dysfunction through a mechanism involving arginase 1

Collado A; Humoud R; Kontidou E; Eldh M; Yang J; Jiao T; Domingo E; Mahdi A; Gabrielsson S; Eriksson P; Zhou Z; Pernow J
Article: PURINERGIC SIGNALLING. 2024;20(1):5-8

Purinergic P2X₃ receptors in the carotid body as new therapeutic targets for controlling heart failure

He X; Zhou Z
Journal article: EUROPEAN HEART JOURNAL. 2023;44:ehad655.3099

Paracrine cardioprotective signaling by red blood cells through hypoxia-mediated activation of soluble guanylate cyclase and release of cyclic guanosine monophosphate

Yang JN; Sundqvist M; Zheng X; Jiao T; Collado A; Mahdi A; Tengbom J; Mergia E; Zhou Z; Carlstrom M; Akaike T; Cortese-Krott M; Weitzberg E; Lundberg JO; Pernow J
Journal article: EUROPEAN HEART JOURNAL. 2023;44:ehad655.3096

Stimulation of soluble guanylyl cyclase in erythrocytes induces export of cGMP and cardioprotection in type 2 diabetes

Jiao T; Collado A; Mahdi A; Tengbom J; Tratsiakovich Y; Milne G; Alvarsson M; Lundberg J; Zhou Z; Yang J; Pernow J
Journal article: EUROPEAN HEART JOURNAL. 2023;44:ehad655.3066

Erythrocyte-derived extracellular vesicles from type 2 diabetes patients induce endothelial dysfunction through arginase 1

Collado A; Humoud R; Eldh M; Jiao T; Domingo E; Kontidou E; Yang J; Mahdi A; Gabrielsson S; Eriksson P; Zhou Z; Pernow J
Article: JOURNAL OF CLINICAL INVESTIGATION. 2023;133(17):e167693

Hypoxic erythrocytes mediate cardioprotection through activation of soluble guanylate cyclase and release of cyclic GMP

Yang J; Sundqvist ML; Zheng X; Jiao T; Collado A; Tratsiakovich Y; Mahdi A; Tengbom J; Mergia E; Catrina S-B; Zhou Z; Carlstroem M; Akaike T; Cortese-Krott MM; Weitzberg E; Lundberg JO; Pernow J
Article: JACC-BASIC TO TRANSLATIONAL SCIENCE. 2023;8(8):907-918

Stimulation of Erythrocyte Soluble Guanylyl Cyclase Induces cGMP Export and Cardioprotection in Type 2 Diabetes

Jiao T; Collado A; Mahdi A; Tengbom J; Tratsiakovich Y; Milne GT; Alvarsson M; Lundberg JO; Zhou Z; Yang J; Pernow J
Article: JCI INSIGHT. 2023;8(6):e160745

The long noncoding RNA THBS1-AS1 promotes cardiac fibroblast activation in cardiac fibrosis by regulating TGFBR1

Zhou J; Tian G; Quan Y; Kong Q; Huang F; Li J; Wu W; Tang Y; Zhou Z; Liu X
Article: PHARMACOLOGICAL RESEARCH. 2023;188:106677

Inhibition of long noncoding RNA Gm41724 alleviates pressure overload-induced cardiac fibrosis by regulating lamina-associated polypeptide 2α

Kong Q; Zhou J; Ma C; Wei Z; Chen Y; Cheng Y; Wu W; Zhou Z; Tang Y; Liu X
Article: JOURNAL OF INTERNAL MEDICINE. 2023;293(2):228-245

The red blood cell as a mediator of endothelial dysfunction in patients with familial hypercholesterolemia and dyslipidemia

Mahdi A; Wodaje T; Kovamees O; Tengbom J; Zhao A; Jiao T; Henricsson M; Yang J; Zhou Z; Nieminen AI; Levin M; Collado A; Brinck J; Pernow J
Article: BASIC RESEARCH IN CARDIOLOGY. 2022;117(1):46

Erythrocytes from patients with ST-elevation myocardial infarction induce cardioprotection through the purinergic P2Y₁₃ receptor and nitric oxide signaling

Jiao T; Collado A; Mahdi A; Jurga J; Tengbom J; Saleh N; Verouhis D; Bohm F; Zhou Z; Yang J; Pernow J
Article: JACC-BASIC TO TRANSLATIONAL SCIENCE. 2022;7(3):193-204

Erythrocytes Induce Vascular Dysfunction in COVID-19

Mahdi A; Collado A; Tengbom J; Jiao T; Wodaje T; Johansson N; Farnebo F; Farnert A; Yang J; Lundberg JO; Zhou Z; Pernow J
Article: DIABETES. 2022;71(2):285-297

Downregulation of Erythrocyte miR-210 Induces Endothelial Dysfunction in Type 2 Diabetes

Zhou Z; Collado A; Sun C; Tratsiakovich Y; Mahdi A; Winter H; Chernogubova E; Seime T; Narayanan S; Jiao T; Jin H; Alvarsson M; Zheng X; Yang J; Hedin U; Catrina S-B; Maegdefessel L; Pernow J
Article: PHARMACOLOGY. 2022;107(3-4):160-166

Therapeutic Potential of Sunitinib in Ameliorating Endothelial Dysfunction in Type 2 Diabetic Rats

Mahdi A; Jiao T; Tratsiakovich Y; Wernly B; Yang J; Ostenson C-G; Danser AHJ; Pernow J; Zhou Z
Article: MEDICAL PRINCIPLES AND PRACTICE. 2022;31(2):187-194

Red Cell Distribution Width Is Independently Associated with Mortality in Sepsis

Dankl D; Rezar R; Mamandipoor B; Zhou Z; Wernly S; Wernly B; Osmani V
Journal article: EUROPEAN HEART JOURNAL. 2021;42(Supplement_1):ehab724.3364

Erythrocytes induce vascular dysfunction in COVID-19

Mahdi A; Collado A; Tengbom J; Jiao T; Wodaje T; Yang J; Lundberg JO; Zhou Z; Pernow J
Article: CURRENT OPINION IN PHARMACOLOGY. 2021;60:183-192

MicroRNA: A mediator of diet-induced cardiovascular protection

Collado A; Jin H; Pernow J; Zhou Z
Article: JOURNAL OF THROMBOSIS AND THROMBOLYSIS. 2021;51(1):226-231

Anti-coagulation for COVID-19 treatment: both anti-thrombotic and anti-inflammatory?

Paar V; Wernly B; Zhou Z; Motloch LJ; Hoppe UC; Egle A; Lichtenauer M
Article: AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 2021;320(1):H90-H94

Ticagrelor: a cardiometabolic drug targeting erythrocyte-mediated purinergic signaling?

Wernly B; Erlinge D; Pernow J; Zhou Z
Article: CELLS. 2020;9(7):E1712-1712

Red Blood Cell Peroxynitrite Causes Endothelial Dysfunction in Type 2 Diabetes Mellitus via Arginase

Mahdi A; Tengbom J; Alvarsson M; Wernly B; Zhou Z; Pernow J
Article: STEM CELL RESEARCH & THERAPY. 2020;11(1):284

Enrichment differentiation of human induced pluripotent stem cells into sinoatrial node-like cells by combined modulation of BMP, FGF, and RA signaling pathways

Liu F; Fang Y; Hou X; Yan Y; Xiao H; Zuo D; Wen J; Wang L; Zhou Z; Dang X; Zhou R; Liao B
Article: WORLD JOURNAL OF SURGICAL ONCOLOGY. 2020;18(1):88

Long-term survival among patients with gastrointestinal stromal tumors diagnosed after another malignancy: a SEER population-based study

Shen C; Wang C; He T; Cai Z; Yin X; Yin Y; Lu D; Zhang B; Zhou Z
Article: FRONTIERS IN PHARMACOLOGY. 2020;11:603226

Erythrocytes Induce Endothelial Injury in Type 2 Diabetes Through Alteration of Vascular Purinergic Signaling

Mahdi A; Tratsiakovich Y; Tengbom J; Jiao T; Garib L; Alvarsson M; Yang J; Pernow J; Zhou Z
Journal article: EUROPEAN HEART JOURNAL. 2019;40(Supplement_1):ehz746.0897

P6299Dietary nitrate restores cardiac ischemic tolerance in type 2 diabetic mice and protects against ischemia-reperfusion injury via soluble guanylate cyclase in red blood cells

Yang JN; Jiao T; Tratsiakovich Y; Mahdi A; Zhou Z; Lundberg JO; Pernow J
Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2019;23(9):6085-6097

miR-499 released during myocardial infarction causes endothelial injury by targeting α7-nAchR

Zhou R; Huang W; Fan X; Liu F; Luo L; Yuan H; Jiang Y; Xiao H; Zhou Z; Deng C; Dang X
Article: JOURNAL OF PHARMACOLOGICAL SCIENCES. 2019;141(1):64-69

Activation of adenosine A_2A but not A_2B receptors is involved in uridine adenosine tetraphosphate-induced porcine coronary smooth muscle relaxation

Sun C; Jiao T; Merkus D; Duncker DJ; Mustafa SJ; Zhou Z
Journal article: FASEB JOURNAL. 2019;33:512.4

Sunitinib Improves Endothelial Function in Type 2 Diabetic Rats

Zhou Z; Mahdi A; Tratsiakovich Y; Jiao T; Yang J; Ostenson C-G; Danser AHJ; Pernow J
Article: FRONTIERS IN PHARMACOLOGY. 2019;10:861

The Effect of Glycemic Control on Endothelial and Cardiac Dysfunction Induced by Red Blood Cells in Type 2 Diabetes

Mahdi A; Jiao T; Yang J; Kovamees O; Alvarsson M; von Heijne M; Zhou Z; Pernow J
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2018;19(12):E3942-3942

Altered Purinergic Receptor Sensitivity in Type 2 Diabetes-Associated Endothelial Dysfunction and Up₄A-Mediated Vascular Contraction

Mahdi A; Jiao T; Tratsiakovich Y; Yang J; Ostenson C-G; Pernow J; Zhou Z
Article: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 2018;72(7):769-780

Erythrocytes From Patients With Type 2 Diabetes Induce Endothelial Dysfunction Via Arginase I

Zhou Z; Mahdi A; Tratsiakovich Y; Zahoran S; Kovamees O; Nordin F; Gonzalez AEU; Alvarsson M; Ostenson C-G; Andersson DC; Hedin U; Hermesz E; Lundberg JO; Yang J; Pernow J
Article: JACC-BASIC TO TRANSLATIONAL SCIENCE. 2018;3(4):450-463

Red Blood Cells in Type 2 Diabetes Impair Cardiac Post-Ischemic Recovery Through an Arginase-Dependent Modulation of Nitric Oxide Synthase and Reactive Oxygen Species

Yang J; Zheng X; Mahdi A; Zhou Z; Tratsiakovich Y; Jiao T; Kiss A; Kovamees O; Alvarsson M; Catrina S-B; Lundberg JO; Brismar K; Pernow J
Article: FRONTIERS IN PHARMACOLOGY. 2018;9:255

Uridine Adenosine Tetraphosphate-Induced Coronary Relaxation Is Blunted in Swine With Pressure Overload: A Role for Vasoconstrictor Prostanoids

Zhou Z; Lankhuizen IM; van Beusekom HM; Cheng C; Duncker DJ; Merkus D
Article: PURINERGIC SIGNALLING. 2017;13(4):591-600

Divergent coronary flow responses to uridine adenosine tetraphosphate in atherosclerotic ApoE knockout mice

Teng B; Labazi H; Sun C; Yang Y; Zeng X; Mustafa SJ; Zhou Z
Article: PURINERGIC SIGNALLING. 2017;13(3):319-329

Altered purinergic signaling in uridine adenosine tetraphosphate-induced coronary relaxation in swine with metabolic derangement

Zhou Z; Sorop O; de Beer VJ; Heinonen I; Cheng C; Danser AHJ; Duncker DJ; Merkus D
Journal article: EUROPEAN HEART JOURNAL. 2017;38(suppl_1):ehx501.280

280Red blood cells from patients with type 2 diabetes mellitus induce vascular endothelial dysfunction via a mechanism involving vascular arginase I and reactive oxygen species

Zhou Z; Mahdi A; Tratsiakovich Y; Kovamees O; Alvarsson M; Yang J; Pernow J
Journal article: EUROPEAN HEART JOURNAL. 2017;38(suppl_1):ehx493.p5386

P5386Red blood cells from patients with type 2 diabetes impair post-ischemic cardiac recovery via a mechanism depending on arginase and nitric oxide synthase

Yang JN; Mahdi A; Zhou Z; Tratsiakovich Y; Kovamees O; Alvarsson M; Pernow J
Journal article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2017;37(suppl_1)

Abstract 378: Red Blood Cells From Patients With Type 2 Diabetes Induce Endothelial Dysfunction Through Up-Regulation of Arginase I

Zhou Z; Mahdi A; Tratsiakovich Y; Kövamees O; Yang J; Pernow J
Article: AMERICAN JOURNAL OF HYPERTENSION. 2017;30(3):304-312

Impaired Aortic Contractility to Uridine Adenosine Tetraphosphate in Angiotensin II-Induced Hypertensive Mice: Receptor Desensitization?

Zhou Z; Yadav VR; Sun C; Teng B; Mustafa JS
Article: AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 2016;311(6):H1339-H1351

Coronary microvascular dysfunction after long-term diabetes and hypercholesterolemia

Sorop O; van den Heuvel M; van Ditzhuijzen NS; de Beer VJ; Heinonen I; van Duin RWB; Zhou Z; Koopmans SJ; Merkus D; van der Giessen WJ; Danser AHJ; Duncker DJ
Journal article: HYPERTENSION. 2016;68(suppl_1)

Abstract P104: Role of Adenosine Receptors in Angiotensin II Dependent Hypertension in Mice

Yadav VR; Zhou Z; Teng B; Mustafa SJ
Article: AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 2016;311(1):H299-H309

Uridine adenosine tetraphosphate acts as a proangiogenic factor in vitro through purinergic P2Y receptors

Zhou Z; Chrifi I; Xu Y; Pernow J; Duncker DJ; Merkus D; Cheng C
Article: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY. 2016;90:30-37

Enhanced A_2A adenosine receptor-mediated increase in coronary flow in type I diabetic mice

Labazi H; Teng B; Zhou Z; Mustafa SJ
Journal article: CIRCULATION. 2015;132(suppl_3)

Abstract 17340: High Fat Diet Exacerbates Uridine Adenosine Tetraphosphate (Up4A)-Mediated Decrease in Coronary Flow in Atherosclerotic ApoE Knockout Mice: Role of Purinergic P2X1 Receptors

ZHOU Z; Teng B; Labazi H; Sun C; Yang Y; Zeng X; Mustafa SJ
Article: VASCULAR PHARMACOLOGY. 2015;73:78-85

Mechanisms underlying uridine adenosine tetraphosphate-induced vascular contraction in mouse aorta: Role of thromboxane and purinergic receptors

Zhou Z; Sun C; Tilley SL; Mustafa SJ
Article: PURINERGIC SIGNALLING. 2015;11(2):263-273

Involvement of NADPH oxidase in A_2A adenosine receptor-mediated increase in coronary flow in isolated mouse hearts

Zhou Z; Rajamani U; Labazi H; Tilley SL; Ledent C; Teng B; Mustafa SJ
Article: AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 2014;306(6):H918-H927

Phosphodiesterase-5 activity exerts a coronary vasoconstrictor influence in awake swine that is mediated in part via an increase in endothelin production

Zhou Z; de Beer VJ; Bender SB; Danser AHJ; Merkus D; Laughlin MH; Duncker DJ
Article: AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY. 2014;306(5):L442-L452

Pulmonary vasoconstrictor influence of endothelin in exercising swine depends critically on phosphodiesterase 5 activity

Zhou Z; de Beer VJ; de Wijs-Meijler D; Bender SB; Hoekstra M; Laughlin MH; Duncker DJ; Merkus D
Article: PHARMACOLOGICAL RESEARCH. 2013;77:22-29

Blunted coronary vasodilator response to uridine adenosine tetraphosphate in post-infarct remodeled myocardium is due to reduced P1 receptor activation

Zhou Z; de Wijs-Meijler D; Lankhuizen I; Jankowski J; Jankowski V; Danser AHJ; Duncker DJ; Merkus D
Article: AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 2013;304(10):H1370-H1381

Phosphodiesterase 5 inhibition-induced coronary vasodilation is reduced after myocardial infarction

Merkus D; Visser M; Houweling B; Zhou Z; Nelson J; Duncker DJ
Article: PHARMACOLOGICAL RESEARCH. 2013;67(1):10-17

Uridine adenosine tetraphosphate is a novel vasodilator in the coronary microcirculation which acts through purinergic P1 but not P2 receptors

Zhou Z; Merkus D; Cheng C; Duckers HJ; Danser AHJ; Duncker DJ
Article: AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 2012;302(8):H1747-H1755

Cytochrome P-450 2C9 exerts a vasoconstrictor influence on coronary resistance vessels in swine at rest and during exercise

Zhou Z; Hemradj V; de Beer VJ; Gao F; Hoekstra M; Merkus D; Duncker DJ
Article: HYPERTENSION. 2012;59(1):151-157

Sunitinib-Induced Systemic Vasoconstriction in Swine Is Endothelin Mediated and Does Not Involve Nitric Oxide or Oxidative Stress

Kappers MHW; de Beer VJ; Zhou Z; Danser AHJ; Sleijfer S; Duncker DJ; van den Meiracker AH; Merkus D
Article: LIFE SCIENCES. 2011;89(13-14):491-497

Disruption of CD38 gene enhances cardiac functions by elevating serum testosterone in the male null mice

Gan L; Jiang W; Xiao Y-F; Deng L; Gu L-D; Guo Z-Y; Zhou Z-C; Wu D; Xin H-B
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Alla övriga publikationer

Review: BRITISH JOURNAL OF PHARMACOLOGY. 2024

Circular RNA regulatory role in pathological cardiac remodelling

Bibi A; Bartekova M; Gandhi S; Greco S; Made A; Sarkar M; Stopa V; Tastsoglou S; de Gonzalo-Calvo D; Devaux Y; Emanueli C; Hatzigeorgiou AG; Nossent AY; Zhou Z; Martelli F
Review: JOURNAL OF PHYSIOLOGY-LONDON. 2023;601(22):4989-5009

Extracellular vesicles and their non-coding RNA cargos: Emerging players in cardiovascular disease

Collado A; Gan L; Tengbom J; Kontidou E; Pernow J; Zhou Z
Review: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2023;43(5):628-636

Erythrocyte-Derived microRNAs: Emerging Players in Cardiovascular and Metabolic Disease

Kontidou E; Collado A; Pernow J; Zhou Z
Conference publication: EUROPEAN HEART JOURNAL. 2022;43:2917

Red blood cells induce endothelial dysfunction in patients with ST-elevation myocardial infarction and elevated C-reactive protein

Tengbom J; Collado A; Jiao T; Yang J; Zhou Z; Mahdi A; Pernow J
Conference publication: EUROPEAN HEART JOURNAL. 2022;43:2921

Arginase 1 in erythrocytes is a critical modulator of cardioprotective signalling by nitric oxide and soluble guanylyl cyclase

Yang JN; Tratsiakovich YT; Jiao TJ; Mahdi AM; Tengbom JT; Zhou ZZ; Collado AC; Lundberg JL; Pernow JP
Conference publication: EUROPEAN HEART JOURNAL. 2022;43:2910

Erythrocytes from patients with ST-elevation myocardial infarction induce cardioprotection via the purinergic P2Y13 receptor and nitric oxide signalling

Jiao T; Mahdi A; Tengbom J; Collado A; Jurga J; Saleh N; Verouhis D; Bohm F; Zhou Z; Yang J; Pernow J
Conference publication: EUROPEAN HEART JOURNAL. 2022;43:3074

Overexpression of miR-210 ameliorates endothelial dysfunction in type 2 diabetic mice

Collado A; Jiao T; Zaccagnini G; Yang J; Carstrom M; Martelli F; Pernow J; Zhou Z
Editorial comment: PURINERGIC SIGNALLING. 2022;18(2):161-163

Purinergic activation in response to hemodynamic force directs heart valve development

Cao X; Zhou Z
Conference publication: DIABETOLOGIA. 2022;65(SUPPL 1):S25

Overexpression of miR-210 attenuates endothelial dysfunction in a mouse model of obesity and type 2 diabetes

Collado A; Jiao T; Zaccagnini G; Yang J; Carlstrom M; Martelli F; Pernow J; Zhou Z
Review: PURINERGIC SIGNALLING. 2021;17(4):705-712

Purinergic interplay between erythrocytes and platelets in diabetes-associated vascular dysfunction

Zhou Z
Conference publication: EUROPEAN HEART JOURNAL. 2021;42:3259

Attenuated cardiac post-ischemic injury and endothelial dysfunction by stimulation of soluble guanylyl cyclase in red blood cells from patients with type 2 diabetes

Jiao T; Zhou Z; Mahdi A; Tengbom J; Tratsiakovich Y; Yang J; Pernow J
Editorial comment: DRUG DISCOVERY TODAY. 2021;26(8):1773-1775

Sunitinib and its effect in the cardiovascular system

Mahdi A; Wernly B; Pernow J; Zhou Z
Review: HELLENIC JOURNAL OF CARDIOLOGY. 2021;62(3):190-200

Infective endocarditis - A review of current therapy and future challenges

Rezar R; Lichtenauer M; Haar M; Hoedl G; Kern JM; Zhou Z; Wuppinger T; Kraus J; Strohmer B; Hoppe UC; Wernly B
Review: BASIC RESEARCH IN CARDIOLOGY. 2021;116(1):22

Adenosine and adenosine receptor-mediated action in coronary microcirculation

Zhang Y; Wernly B; Cao X; Mustafa SJ; Tang Y; Zhou Z
Preprint: SSRN. 2021

Erythrocytes Induce Vascular Dysfunction in COVID-19

Mahdi A; Collado A; Tengbom J; Jiao T; Wodaje T; Johanssson N; Farnebo F; Färnert A; Yang J; Lundberg J; Zhou Z; Pernow J
Preprint: SSRN ELECTRONIC JOURNAL. 2021

Erythrocytes Induce Vascular Dysfunction in COVID-19

Mahdi A; Collado A; Tengbom J; Jiao T; Wodaje T; Johanssson N; Farnebo F; Färnert A; Yang J; Lundberg JO; Zhou Z; Pernow J
Review: FRONTIERS IN PHARMACOLOGY. 2021;12:654425

P2X7 Receptor-Mediated Inflammation in Cardiovascular Disease

Zhou J; Zhou Z; Liu X; Yin H-Y; Tang Y; Cao X
Conference publication: EUROPEAN HEART JOURNAL. 2021;42:3364

Erythrocytes induce vascular dysfunction in COVID-19

Mahdi A; Collado A; Tengbom J; Jiao T; Wodaje T; Yang J; Lundberg JO; Zhou Z; Pernow J
Review: AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 2020;319(4):H723-H729

More purinergic receptors deserve attention as therapeutic targets for the treatment of cardiovascular disease

Wernly B; Zhou Z
Review: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2020;9(18):e017404

Purinergic Dysfunction in Pulmonary Arterial Hypertension

Cai Z; Tu L; Guignabert C; Merkus D; Zhou Z
Preprint: RESEARCH SQUARE. 2020

Enrichment differentiation of human induced pluripotent stem cells into sinoatrial node-like cells by combined modulation of BMP, FGF and RA signaling pathways

Liu F; Fang Y; Hou X; Yan Y; Xiao H; Zuo D; Wen J; Wang L; Zhou Z; Dang X; Zhou R; Liao B
Preprint: RESEARCH SQUARE. 2020

Enrichment differentiation of human induced pluripotent stem cells into sinoatrial node-like cells by combined modulation of BMP, FGF and RA signaling pathways

Liu F; Fang Y; Hou X; Yan Y; Xiao H; Zuo D; Wen J; Wang L; Zhou Z; Dang X; Zhou R; Liao B
Review: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY. 2020;140:1-9

Alteration of purinergic signaling in diabetes: Focus on vascular function

Zhou R; Dang X; Sprague RS; Mustafa SJ; Zhou Z
Conference publication: WIENER KLINISCHE WOCHENSCHRIFT. 2020;132:S217

COVID-19 treatment by anti-coagulation: anti-thrombotic and anti-inflammatory?

Paar V; Wernly B; Zhou Z; Motloch LJ; Hoppe UC; Egle A; Lichtenauer M
Editorial comment: FRONTIERS IN PHARMACOLOGY. 2020;11:1200

A 15-Year Study on Up₄A in Cardiovascular Disease

Zhou Z; Matsumoto T
Review: CARDIOVASCULAR RESEARCH. 2019;115(11):1596-1605

Red blood cell dysfunction: a new player in cardiovascular disease

Pernow J; Mahdi A; Yang J; Zhou Z
Review: PHARMACOLOGICAL RESEARCH. 2019;141:32-45

Uridine adenosine tetraphosphate and purinergic signaling in cardiovascular system: An update

Zhou Z; Matsumoto T; Jankowski V; Pernow J; Mustafa SJ; Duncker DJ; Merkus D
Conference publication: EUROPEAN HEART JOURNAL. 2019;40:3903

Dietary nitrate restores cardiac ischemic tolerance in type 2 diabetic mice and protects against ischemia-reperfusion injury via soluble guanylate cyclase in red blood cells

Yang JN; Jiao T; Tratsiakovich Y; Mahdi A; Zhou Z; Lundberg JO; Pernow J
Editorial comment: AGING-US. 2018;10(12):3643-3644

Erythrocytes and cardiovascular complications

Zhou Z; Yang J; Pernow J
Conference publication: CARDIOVASCULAR RESEARCH. 2018;114:S42

Vascular endothelial growth factor receptor 2 inhibition improves endothelial function in type 2 diabetic rats: a link to purinergic signalling?

Mahdi A; Tratsiakovich Y; Yang J; Ostenson C-G; Danser JAH; Pernow J; Zhou Z
Conference publication: CARDIOVASCULAR RESEARCH. 2018;114:S26-S27

Inorganic nitrate restores cardiac ischemic tolerance in type 2 diabetic db/db mice and protects against ischemia-reperfusion injury via an effect mediated through red blood cells

Yang JN; Tratsiakovich Y; Mahdi A; Zhou Z; Lundberg JO; Pernow J
Conference publication: CARDIOVASCULAR RESEARCH. 2018;114:S42

Red blood cells from patients with type 2 diabetes mellitus induce endothelial dysfunction through NADPH oxidase-derived reactive oxygen species

Zhou Z; Mahdi A; Tratsiakovich Y; Yang J; Pernow J
Conference publication: HYPERTENSION. 2018;68:715.2

Role of Adenosine Receptors in Angiotensin II Dependent Hypertension in Mice

Yadav VR; Zhou Z; Teng B; Mustafa SJ
Conference publication: FASEB JOURNAL. 2018;32(1)

Role of A₁ and A_2B Adenosine receptors in Angiotensin II dependent hypertension in mice

Yadav VR; Zhou Z; Teng B; Mustafa SJS
Conference publication: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2017;37

Red Blood Cells From Patients With Type 2 Diabetes Induce Endothelial Dysfunction Through Up-Regulation of Arginase I

Zhou Z; Mahdi A; Tratsiakovich Y; Kovamees O; Yang J; Pernow J
Conference publication: EUROPEAN HEART JOURNAL. 2017;38:1140

Red blood cells from patients with type 2 diabetes impair post-ischemic cardiac recovery via a mechanism depending on arginase and nitric oxide synthase

Yang JN; Mahdi A; Zhou Z; Tratsiakovich Y; Kovamees O; Alvarsson M; Pernow J
Conference publication: EUROPEAN HEART JOURNAL. 2017;38:51-52

Red blood cells from patients with type 2 diabetes mellitus induce vascular endothelial dysfunction via a mechanism involving vascular arginase I and reactive oxygen species

Zhou Z; Mahdi A; Tratsiakovich Y; Kovamees O; Alvarsson M; Yang J; Pernow J
Conference publication: FASEB JOURNAL. 2016;30

Impaired Vascular Contractility to Uridine Adenosine Tetraphosphate (Up₄A) in Angiotensin (Ang) II-Induced Hypertensive Mice: The Receptor Desensitization?

Zhou Z; Yadav VR; Sun C; Teng B; Mustafa SJ
Conference publication: CIRCULATION. 2015;132

High Fat Diet Exacerbates Uridine Adenosine Tetraphosphate (Up4A)-Mediated Decrease in Coronary Flow in Atherosclerotic ApoE Knockout Mice: Role of Purinergic P2X1 Receptors

Zhou Z; Teng B; Labazi H; Sun C; Yang Y; Zeng X; Mustafa SJ
Conference publication: FASEB JOURNAL. 2013;27:1185.5

Phosphodiesterase-5 activity exerts a coronary vasoconstrictor influence in awake swine that is partly mediated via an increase in endothelin production

Duncker DJ; Zhou Z; de Beer VJ; Merkus D
Conference publication: FASEB JOURNAL. 2013;27:898.1

Cytochrome P450 2C9 contributes to pulmonary vasoconstriction in exercising swine

Zhou Z; de Beer VJ; Duncker DJ; Merkus D
Conference publication: JOURNAL OF VASCULAR RESEARCH. 2013;50:15

ALTERED CORONARY ENDOTHELIAL SIGNALING IN RESPONSE TO URIDINE ADENOSINE TETRAPHOSPHATE IN DIABETES

Zhou Z; Sorop O; De Beer VJ; Heinonen I; Danser AHJ; Merkus D; Duncker DJ
Conference publication: FASEB JOURNAL. 2012;26:1055.5

Uridine adenosine tetraphosphate (Up4A) as a novel coronary vasodilator in health and disease: Role of purinergic P1 and P2 receptors

Zhou Z; Duncker DJ; Merkus D
Conference publication: CIRCULATION. 2012;126(21)

Uridine Adenosine Tetraphosphate (Up4A)-Induced Coronary Vasodilation is Blunted in Swine with Aortic Banding: A Role for Prostanoids?

Zhou Z; Jankowski J; Duncker D; Merkus D
Conference publication: CIRCULATION. 2011;124(21)

Vascular Endothelial Growth Factor Inhibition Results in Systemic Hypertension Mediated by Alterations in Endothelin-1, but Not by Alterations in Nitric Oxide or Reactive Oxygen Species

de Beer VJ; Kappers MH; Zhou Z; van den Meiracker AH; Danser AHJ; Sleijfer S; Duncker DJ; Merkus D
Letter: JOURNAL OF APPLIED PHYSIOLOGY. 2011;110(1):289-294

LOW PULMONARY VASCULAR RESISTANCE BREAKS THE TWO-HOUR MARATHON LIMIT

Merkus D; Zhou Z
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