Yvonne Freund-Levi

Publikationer
Forskningsbidrag
CV
Populärvetenskap och samverkan

Artiklar

Article: ALZHEIMERS & DEMENTIA. 2024;20(10):6682-6698
Blood-based multivariate methylation risk score for cognitive impairment and dementia
Koetsier J; Cavill R; Reijnders R; Harvey J; Homann J; Kouhsar M; Deckers K; Kohler S; Eijssen LMT; van den Hove DLA; Demuth I; Duezel S; Smith RG; Smith AR; Burrage J; Walker EM; Shireby G; Hannon E; Dempster E; Frayling T; Mill J; Dobricic V; Johannsen P; Wittig M; Franke A; Vandenberghe R; Schaeverbeke J; Freund-Levi Y; Froelich L; Scheltens P; Teunissen CE; Frisoni G; Blin O; Richardson JC; Bordet R; Engelborghs S; de Roeck E; Martinez-Lage P; Tainta M; Lleo A; Sala I; Popp J; Peyratout G; Verhey F; Tsolaki M; Andreasson U; Blennow K; Zetterberg H; Streffer J; Vos SJB; Lovestone S; Visser P-J; Lill CM; Bertram L; Lunnon K; Pishva E
Article: ALZHEIMERS & DEMENTIA. 2024;20(10):6722-6739
Blood DNA methylomic signatures associated with CSF biomarkers of Alzheimer's disease in the EMIF-AD study
Smith RG; Pishva E; Kouhsar M; Imm J; Dobricic V; Johannsen P; Wittig M; Franke A; Vandenberghe R; Schaeverbeke J; Freund-Levi Y; Froelich L; Scheltens P; Teunissen CE; Frisoni G; Blin O; Richardson JC; Bordet R; Engelborghs S; de Roeck E; Martinez-Lage P; Altuna M; Tainta M; Lleo A; Sala I; Popp J; Peyratout G; Winchester L; Nevado-Holgado A; Verhey F; Tsolaki M; Andreasson U; Blennow K; Zetterberg H; Streffer J; Vos SJB; Lovestone S; Visser PJ; Bertram L; Lunnon K
Article: RES SQ. 2024
Synaptic protein CSF levels relate to memory scores in individuals without dementia.
Wesenhagen KEJ; de Leeuw DM; Tomassen J; Gobom J; Bos I; Vos SJB; Martinez-Lage P; Tainta M; Popp J; Peyratout G; Tsolaki M; Vandenberghe R; Freund-Levi Y; Verhey F; Lovestone S; Streffer J; Dobricic V; Blennow K; Scheltens P; Smit AB; Bertram L; Teunissen CE; Zetterberg H; Tijms BM; Alzheimer’s Disease Neuroimaging Initiative
Article: FLUIDS AND BARRIERS OF THE CNS. 2024;21(1):58
Involvement of the choroid plexus in Alzheimer's disease pathophysiology: findings from mouse and human proteomic studies
Delvenne A; Vandendriessche C; Gobom J; Burgelman M; Dujardin P; De Nolf C; Tijms BM; Teunissen CE; Schindler SE; Verhey F; Ramakers I; Martinez-Lage P; Tainta M; Vandenberghe R; Schaeverbeke J; Engelborghs S; De Roeck E; Popp J; Peyratout G; Tsolaki M; Freund-Levi Y; Lovestone S; Streffer J; Bertram L; Blennow K; Zetterberg H; Visser PJ; Vandenbroucke RE; Vos SJB
Article: ALZHEIMERS & DEMENTIA. 2024;:6205-6220
CSF proteomic profiles of neurodegeneration biomarkers in Alzheimer's disease
Delvenne A; Gobom J; Schindler SE; ten Kate M; Reus LM; Dobricic V; Tijms BM; Benzinger TLS; Cruchaga C; Teunissen CE; Ramakers I; Martinez-Lage P; Tainta M; Vandenberghe R; Schaeverbeke J; Engelborghs S; De Roeck E; Popp J; Peyratout G; Tsolaki M; Freund-Levi Y; Lovestone S; Streffer J; Barkhof F; Bertram L; Blennow K; Zetterberg H; Visser PJ; Vos SJB
Article: JOURNAL OF ALZHEIMERS DISEASE. 2024;98(4):1391-1401
High Contrast PET Imaging of Subcortical and Allocortical Amyloid-β in Early Alzheimer's Disease Using [¹¹C]AZD2184
Mattsson P; Cselenyi Z; Moren AF; Freund-Levi Y; Wahlund L-O; Halldin C; Farde L
Journal article: ALZHEIMERS & DEMENTIA. 2023;19(S14)
Blood DNA methylomic signatures associated with CSF biomarkers of Alzheimer’s disease in the EMIF‐AD Multimodal Biomarker Discovery study
Smith RG; Imm JL; Dobricic V; Sommerer Y; Bos I; Vos SJB; Verhey FRJ; Scheltens P; Engelborgs S; Frisoni GB; Blin O; Richardson JC; Bordet R; Tsolaki M; Popp J; Martinez‐Lage P; Lleo A; Johannsen P; Freund‐Levi Y; Lutz F; Vandenberghe R; Wittig M; Frank A; Lovestone S; Streffer J; Andreasson U; Blennow K; Visser PJ; Zetterberg H; Bertram L; Lunnon K
Article: ALZHEIMERS & DEMENTIA. 2023;19(6):2317-2331
Whole-exome rare-variant analysis of Alzheimer's disease and related biomarker traits
Kucukali F; Neumann A; Van Dongen J; De Pooter T; Joris G; De Rijk P; Ohlei O; Dobricic V; Bos I; Vos SJB; Engelborghs S; De Roeck E; Vandenberghe R; Gabel S; Meersmans K; Tsolaki M; Verhey F; Martinez-Lage P; Tainta M; Frisoni G; Blin O; Richardson JC; Bordet R; Scheltens P; Popp J; Peyratout G; Johannsen P; Frolich L; Freund-Levi Y; Streffer J; Lovestone S; Legido-Quigley C; Ten Kate M; Barkhof F; Zetterberg H; Bertram L; Strazisar M; Visser PJ; Van Broeckhoven C; Sleegers K
Article: JOURNAL OF NEUROENDOCRINOLOGY. 2023;35(5):e13272
Higher CSF/serum free-T4 ratio is associated with improvement of quality of life during treatment with L-thyroxine
Funkquist A; Wandt B; Blennow K; Zetterberg H; Svensson J; Bjellerup P; Freund-Levi Y; Sjoberg S
Article: ALZHEIMERS & DEMENTIA. 2023;19(3):807-820
Cerebrospinal fluid proteomic profiling of individuals with mild cognitive impairment and suspected non-Alzheimer's disease pathophysiology
Delvenne A; Gobom J; Tijms B; Bos I; Reus LM; Dobricic V; Ten Kate M; Verhey F; Ramakers I; Scheltens P; Teunissen CE; Vandenberghe R; Schaeverbeke J; Gabel S; Popp J; Peyratout G; Martinez-Lage P; Tainta M; Tsolaki M; Freund-Levi Y; Lovestone S; Streffer J; Barkhof F; Bertram L; Blennow K; Zetterberg H; Visser PJ; Vos SJB
Article: JPAD-JOURNAL OF PREVENTION OF ALZHEIMERS DISEASE. 2023;10(2):207-211
The Geras Solutions Cognitive Test for Assessing Cognitive Impairment: Normative Data from a Population-Based Cohort
Bloniecki V; Ulfvarson J; Javanshiri K; Hagman G; Freund-Levi Y; Nordstroemg A
Article: BMJ OPEN. 2022;12(11):e066834
Swedish Chronic Pain Biobank: protocol for a multicentre registry and biomarker project
Ghafouri B; Ernberg M; Andrell P; Backryd E; Fisher MR; Freund-Levi Y; Grelz H; Grabel O; Karlsten R; Kosek E; Lofgren M; Ringqvist A; Rudling K; Stalnacke B-M; Sorlen N; Uhlin K; Westergren H; Gerdle B
Article: ALZHEIMERS & DEMENTIA. 2022;18(10):1832-1845
Characteristics of subjective cognitive decline associated with amyloid positivity
Janssen O; Jansen WJ; Vos SJB; Boada M; Parnetti L; Gabryelewicz T; Fladby T; Molinuevo JL; Villeneuve S; Hort J; Epelbaum S; Lleo A; Engelborghs S; van der Flier WM; Landau S; Popp J; Wallin A; Scheltens P; Rikkert MO; Snyder PJ; Rowe C; Chetelat G; Ruiz A; Marquie M; Chipi E; Wolfsgruber S; Heneka M; Boecker H; Peters O; Jarholm J; Rami L; Tort-Merino A; Binette AP; Poirier J; Rosa-Neto P; Cerman J; Dubois B; Teichmann M; Alcolea D; Fortea J; Sanchez-Saudinos MB; Ebenau J; Pocnet C; Eckerstrom M; Thompson L; Villemagne V; Buckley R; Burnham S; Delarue M; Freund-Levi Y; Wallin AK; Ramakers I; Tsolaki M; Soininen H; Hampel H; Spiru L; Tijms B; Ossenkoppele R; Verhey FRJ; Jessen F; Visser PJ
Article: MOLECULAR PSYCHIATRY. 2022;27(4):1990-1999
Rare variants in IFFO1, DTNB, NLRC3 and SLC22A10 associate with Alzheimer's disease CSF profile of neuronal injury and inflammation
Neumann A; Kucukali F; Bos I; Vos SJB; Engelborghs S; De Pooter T; Joris G; De Rijk P; De Roeck E; Tsolaki M; Verhey F; Martinez-Lage P; Tainta M; Frisoni G; Blin O; Richardson J; Bordet R; Scheltens P; Popp J; Peyratout G; Johannsen P; Froelich L; Vandenberghe R; Freund-Levi Y; Streffer J; Lovestone S; Legido-Quigley C; ten Kate M; Barkhof F; Strazisar M; Zetterberg H; Bertram L; Visser PJ; van Broeckhoven C; Sleegers K
Article: MOLECULAR NEURODEGENERATION. 2022;17(1):27
Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer's disease
Visser PJ; Reus LM; Gobom J; Jansen I; Dicks E; van der Lee SJ; Tsolaki M; Verhey FRJ; Popp J; Martinez-Lage P; Vandenberghe R; Lleo A; Molinuevo JL; Engelborghs S; Freund-Levi Y; Froelich L; Sleegers K; Dobricic V; Lovestone S; Streffer J; Vos SJB; Bos I; Smit AB; Blennow K; Scheltens P; Teunissen CE; Bertram L; Zetterberg H; Tijms BM
Article: JAMA NEUROLOGY. 2022;79(3):228-243
Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum
Jansen WJ; Janssen O; Tijms BM; Vos SJB; Ossenkoppele R; Visser PJ
Article: ALZHEIMER'S AND DEMENTIA: DIAGNOSIS, ASSESSMENT AND DISEASE MONITORING. 2022;14(1):e12286
Effects of age, amyloid, sex, and APOE e4 on the CSF proteome in normal cognition
Wesenhagen KEJ; Gobom J; Bos I; Vos SJB; Martinez-Lage P; Popp J; Tsolaki M; Vandenberghe R; Freund-Levi Y; Verhey F; Lovestone S; Streffer J; Dobricic V; Bertram L; Blennow K; Pikkarainen M; Hallikainen M; Kuusisto J; Laakso M; Soininen H; Scheltens P; Zetterberg H; Teunissen CE; Visser PJ; Tijms BM
Article: JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES. 2022;34(3):214-223
Neuropsychiatric Symptoms in Dementia: Considering a Clinical Role for Electroencephalography
Holmgren S; Andersson T; Berglund A; Aarsland D; Cummings J; Freund-Levi Y
Article: BIOMEDICINES. 2021;9(11):1610
Sex-Specific Metabolic Pathways Were Associated with Alzheimer's Disease (AD) Endophenotypes in the European Medical Information Framework for AD Multimodal Biomarker Discovery Cohort
Xu J; Green R; Kim M; Lord J; Ebshiana A; Westwood S; Baird AL; Nevado-Holgado AJ; Shi L; Hye A; Snowden SG; Bos I; Vos SJB; Vandenberghe R; Teunissen CE; Kate MT; Scheltens P; Gabel S; Meersmans K; Blin O; Richardson J; De Roeck EE; Engelborghs S; Sleegers K; Bordet R; Rami L; Kettunen P; Tsolaki M; Verhey FRJ; Alcolea D; Lleo A; Peyratout G; Tainta M; Johannsen P; Freund-Levi Y; Froelich L; Dobricic V; Frisoni GB; Molinuevo JL; Wallin A; Popp J; Martinez-Lage P; Bertram L; Blennow K; Zetterberg H; Streffer J; Visser PJ; Lovestone S; Proitsi P; Legido-Quigley C
Article: JOURNAL OF ALZHEIMERS DISEASE. 2021;83(3):1291-1301
Effects of Peroral Omega-3 Fatty Acid Supplementation on Cerebrospinal Fluid Biomarkers in Patients with Alzheimer's Disease: A Randomized Controlled Trial-The OmegAD Study
Tofiq A; Zetterberg H; Blennow K; Basun H; Cederholm T; Eriksdotter M; Faxen-Irving G; Hjorth E; Jerneren F; Schultzberg M; Wahlund L-O; Palmblad J; Freund-Levi Y
Article: ALZHEIMERS & DEMENTIA. 2021;17(9):1452-1464
Replication study of plasma proteins relating to Alzheimer's pathology
Shi L; Winchester LM; Westwood S; Baird AL; Anand SN; Buckley NJ; Hye A; Ashton NJ; Bos I; Vos SJB; ten Kate M; Scheltens P; Teunissen CE; Vandenberghe R; Gabel S; Meersmans K; Engelborghs S; De Roeck EE; Sleegers K; Frisoni GB; Blin O; Richardson JC; Bordet R; Molinuevo JL; Rami L; Wallin A; Kettunen P; Tsolaki M; Verhey F; Lleo A; Sala I; Popp J; Peyratout G; Martinez-Lage P; Tainta M; Johannsen P; Freund-Levi Y; Froeich L; Dobricic V; Legido-Quigley C; Barkhof F; Andreasson U; Blennow K; Zetterberg H; Streffer J; Lill CM; Bertram L; Visser PJ; Kolb HC; Narayan VA; Lovestone S; Nevado-Holgado AJ
Article: PROTEOMES. 2021;9(3):36
CSF Proteomic Alzheimer's Disease-Predictive Subtypes in Cognitively Intact Amyloid Negative Individuals
Tijms BM; Gobom J; Teunissen C; Dobricic V; Tsolaki M; Verhey F; Popp J; Martinez-Lage P; Vandenberghe R; Lleo A; Molinuevo JL; Engelborghs S; Freund-Levi Y; Froelich L; Bertram L; Lovestone S; Streffer J; Vos S; Blennow K; Scheltens P; Zetterberg H; Visser PJ
Article: ALZHEIMERS RESEARCH & THERAPY. 2021;13(1):64
Research diagnostic criteria for Alzheimer's disease: findings from the LipiDiDiet randomized controlled trial
Rosenberg A; Solomon A; Soininen H; Visser PJ; Blennow K; Hartmann T; Kivipelto M
Journal article: ALZHEIMERS & DEMENTIA. 2020;16(S3)
CSF proteomic profiling of mild cognitive impairment individuals with suspected non‐Alzheimer’s disease pathophysiology
Delvenne A; Gobom J; Tijms BM; Bos I; Verhey FR; Ramakers IH; Scheltens P; Teunissen CE; Vandenberghe R; Gabel S; Popp J; Peyratout G; Martinez‐Lage P; Tainta M; Tsolaki M; Freund‐Levi Y; Lovestone S; Streffer J; Blennow K; Zetterberg H; Visser PJ; Vos SJ
Journal article: ALZHEIMERS & DEMENTIA. 2020;16(S3)
Synaptic proteins relate to memory scores in preclinical Alzheimer’s disease and cognitively healthy controls depending on amyloid
Wesenhagen KEJ; Visser PJ; Gobom J; Bos I; Vos SJB; Martinez‐Lage P; Tainta M; Popp J; Peyratout G; Tsolaki M; Vandenberghe R; Freund‐Levi Y; Verhey FRJ; Lovestone S; Streffer J; Blennow K; Scheltens P; Teunissen CE; Zetterberg H; Tijms BM; Initiative ADN
Article: ALZHEIMERS RESEARCH & THERAPY. 2020;12(1):153
Are neuropsychiatric symptoms in dementia linked to CSF biomarkers of synaptic and axonal degeneration?
Bloniecki V; Zetterberg H; Aarsland D; Vannini P; Kvartsberg H; Winblad B; Blennow K; Freund-Levi Y
Article: JOURNAL OF ALZHEIMERS DISEASE. 2020;77(3):1353-1368
Dickkopf-1 Overexpression in vitro Nominates Candidate Blood Biomarkers Relating to Alzheimer's Disease Pathology
Shi L; Winchester LM; Liu BY; Killick R; Ribe EM; Westwood S; Baird AL; Buckley NJ; Hong S; Dobricic V; Kilpert F; Franke A; Kiddle S; Sattlecker M; Dobson R; Cuadrado A; Hye A; Ashton NJ; Morgan AR; Bos I; Vos SJB; ten Kate M; Scheltens P; Vandenberghe R; Gabel S; Meersmans K; Engelborghs S; De Roeck EE; Sleegers K; Frisoni GB; Blin O; Richardson JC; Bordet R; Molinuevo JL; Rami L; Wallin A; Kettunen P; Tsolaki M; Verhey F; Lleo A; Alcolea D; Popp J; Peyratout G; Martinez-Lage P; Tainta M; Johannsen P; Teunissen CE; Freund-Levi Y; Frolich L; Legido-Quigley C; Barkhof F; Blennow K; Rasmussen KL; Nordestgaard BG; Frikke-Schmidt R; Nielsen SF; Soininen H; Vellas B; Kloszewska I; Mecocci P; Zetterberg H; Morgan BP; Streffer J; Visser PJ; Bertram L; Nevado-Holgado AJ; Lovestone S
Article: JOURNAL OF ALZHEIMERS DISEASE. 2020;74(1):213-225
Validation of Plasma Proteomic Biomarkers Relating to Brain Amyloid Burden in the EMIF-Alzheimer's Disease Multimodal Biomarker Discovery Cohort
Westwood S; Baird AL; Anand SN; Nevado-Holgado AJ; Kormilitzin A; Shi L; Hye A; Ashton NJ; Morgan AR; Bos I; Vos SJB; Baker S; Buckley NJ; Ten Kate M; Scheltens P; Teunissen CE; Vandenberghe R; Gabel S; Meersmans K; Engelborghs S; De Roeck EE; Sleegers K; Frisoni GB; Blin O; Richardson JC; Bordet R; Molinuevo JL; Rami L; Wallin A; Kettunen P; Tsolaki M; Verhey F; Lleo A; Sala I; Popp J; Peyratout G; Martinez-Lage P; Tainta M; Johannsen P; Freund-Levi Y; Froelich L; Dobricic V; Legido-Quigley C; Bertram L; Barkhof F; Zetterberg H; Morgan BP; Streffer J; Visser PJ; Lovestone S
Article: LANCET NEUROLOGY. 2019;18(11):1034-1044
Biomarker-based prognosis for people with mild cognitive impairment (ABIDE): a modelling study
van Maurik IS; Vos SJ; Bos I; Bouwman FH; Teunissen CE; Scheitens P; Barkhof F; Frolich L; Kornhuber J; Wiftfang J; Maier W; Peters O; ROther E; Nobili F; Frisoni GB; Spiru L; Freund-Levi Y; Wallin AK; Hampel H; Soininen H; Tsolaki M; Verhey F; Kloszewska I; Mecocci P; Vellas B; Lovestone S; Gailuzzi S; Herukka S-K; Santana I; Baldeiras I; de Mendonca A; Silva D; Chetelat G; Egret S; Palmqvist S; Hansson O; Visser PJ; Berkhof J; van der Flier WM
Article: ALZHEIMERS & DEMENTIA. 2019;15(11):1478-1488
Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay
Shi L; Westwood S; Baird AL; Winchester L; Dobricic V; Kilpert F; Hong S; Franke A; Hye A; Ashton NJ; Morgan AR; Bos I; Vos SJB; Buckley NJ; ten Kate M; Scheltens P; Vandenberghe R; Gabel S; Meersmans K; Engelborghs S; De Roeck EE; Sleegers K; Frisoni GB; Blin O; Richardson JC; Bordet R; Molinuevo JL; Rami L; Wallin A; Kettunen P; Tsolaki M; Verhey F; Lleo A; Alcolea D; Popp J; Peyratout G; Martinez-Lage P; Tainta M; Johannsen P; Teunissen CE; Freund-Levi Y; Froelich L; Legido-Quigley C; Barkhof F; Blennow K; Zetterberg H; Baker S; Morgan BP; Streffer J; Visser PJ; Bertram L; Lovestone S; Nevado-Holgado AJ
Article: ALZHEIMERS & DEMENTIA. 2019;15(7):888-898
Duration of preclinical, prodromal, and dementia stages of Alzheimer's disease in relation to age, sex, and APOE genotype
Vermunt L; Sikkes SAM; van den Hout A; Handels R; Bos I; van der Flier WM; Kern S; Ousset P-J; Maruff P; Skoog I; Verhey FRJ; Freund-Levi Y; Tsolaki M; Wallin AK; Rikkert MO; Soininen H; Spiru L; Zetterberg H; Blennow K; Scheltens P; Muniz-Terrera G; Visser PJ; Vellas B; Reynish E; Ousset PJ; Andrieu S; Burns A; Pasquier F; Frisoni G; Salmon E; Michel JP; Zekry DS; Boada M; Dartigues JF; Olde-Rikkert MGM; Rigaud AS; Winblad B; Malick A; Sinclair A; Froelich L; Scheltens P; Ribera C; Touchon J; Robert P; Salva A; Waldemar G; Bullock R; Tsolaki M; Rodriguez G; Spiru L; Jones RW; Stiens G; Stoppe G; Jonhagen EM; Cherubini A; Lage PM; Gomezisla T; Camus V; Aguera-Morales E; Lopez F; Savy S; Cantet C; Coley N
Article: ALZHEIMERS & DEMENTIA. 2019;15(6):742-753
Longitudinal cerebrospinal fluid biomarker trajectories along the Alzheimer's disease continuum in the BIOMARKAPD study
Lleo A; Alcolea D; Martinez-Lage P; Scheltens P; Parnetti L; Poirier J; Simonsen AH; Verbeek MM; Rosa-Neto P; Slot RER; Tainta M; Izaguirre A; Reijs BLR; Farotti L; Tsolaki M; Vandenbergue R; Freund-Levi Y; Verhey FRJ; Clarimon J; Fortea J; Frolich L; Santana I; Luis Molinuevo J; Lehmann S; Visser PJ; Teunissen CE; Zetterberg H; Blennow K
Article: ALZHEIMERS & DEMENTIA. 2019;15(6):817-827
Primary fatty amides in plasma associated with brain amyloid burden, hippocampal volume, and memory in the European Medical Information Framework for Alzheimer's Disease biomarker discovery cohort
Kim M; Snowden S; Suvitaival T; Ali A; Merkler DJ; Ahmad T; Westwood S; Baird A; Proitsi P; Nevado-Holgado A; Hye A; Bos I; Vos S; Vandenberghe R; Teunissen C; ten Kate M; Scheltens P; Gabel S; Meersmans K; Blin O; Richardson J; De Roeck E; Sleegers K; Bordet R; Rami L; Kettunen P; Tsolaki M; Verhey F; Sala I; Lleo A; Peyratout G; Tainta M; Johannsen P; Freund-Levi Y; Frolich L; Dobricic V; Engelborghs S; Frisoni GB; Molinuevo JL; Wallin A; Popp J; Martinez-Lage P; Bertram L; Barkhof F; Ashton N; Blennow K; Zetterberg H; Streffer J; Visser PJ; Lovestone S; Legido-Quigley C
Article: JOURNAL OF ALZHEIMERS DISEASE. 2019;69(1):189-197
Homocysteine Status Modifies the Treatment Effect of Omega-3 Fatty Acids on Cognition in a Randomized Clinical Trial in Mild to Moderate Alzheimer's Disease: The OmegAD Study
Jerneren F; Cederholm T; Refsum H; Smith AD; Turner C; Palmblad J; Eriksdotter M; Hjorth E; Faxen-Irving G; Wahlund L-O; Schultzberg M; Basun H; Freund-Levi Y
Article: ALZHEIMERS & DEMENTIA. 2019;15(5):644-654
Cerebrospinal fluid biomarkers of neurodegeneration, synaptic integrity, and astroglial activation across the clinical Alzheimer's disease spectrum
Bos I; Vos S; Verhey F; Scheltens P; Teunissen C; Engelborghs S; Sleegers K; Frisoni G; Blin O; Richardson JC; Bordet R; Tsolaki M; Popp J; Peyratout G; Martinez-Lage P; Tainta M; Lleo A; Johannsen P; Freund-Levi Y; Froelich L; Vandenberghe R; Westwood S; Dobricic V; Barkhof F; Legido-Quigley C; Bertram L; Lovestone S; Streffer J; Andreasson U; Blennow K; Zetterberg H; Visser PJ
Article: ALZHEIMER'S AND DEMENTIA: TRANSLATIONAL RESEARCH AND CLINICAL INTERVENTIONS. 2019;5(1):933-938
A metabolite-based machine learning approach to diagnose Alzheimer-type dementia in blood: Results from the European Medical Information Framework for Alzheimer disease biomarker discovery cohort
Stamate D; Kim M; Proitsi P; Westwood S; Baird A; Nevado-Holgado A; Hye A; Bos I; Vos SJB; Vandenberghe R; Teunissen CE; Ten Kate M; Scheltens P; Gabel S; Meersmans K; Blin O; Richardson J; De Roeck E; Engelborghs S; Sleegers K; Bordet R; Ramit L; Kettunen P; Tsolaki M; Verhey F; Alcolea D; Lleo A; Peyratout G; Tainta M; Johannsen P; Freund-Levi Y; Frolich L; Dobricic V; Frisoni GB; Molinuevo JL; Wallin A; Popp J; Martinez-Lage P; Bertram L; Blennow K; Zetterberg H; Streffer J; Visser PJ; Lovestone S; Legido-Quigley C
Journal article: ALZHEIMERS & DEMENTIA. 2018;14(7S_Part_14):p780-p781
P2‐270: INCREASED CSF AMYLOID‐β 1‐38 AND 1‐40 CONCENTRATIONS IN INDIVIDUALS WITH MILD COGNITIVE IMPAIRMENT WITH TAU BUT WITHOUT AMYLOID PATHOPHYSIOLOGY
Vos SJB; Bos I; Verhey FRJ; Engelborghs S; Lleó A; Johannsen P; Freund-Levi Y; Frölich L; Vandenberghe R; Frisoni GB; Blin O; Richardson J; Bordet R; Scheltens P; Ramakers IHGB; Popp J; Tsolaki M; Martinez-Lage P; Bertram L; Lovestone S; Streffer J; Blennow K; Andreasson U; Zetterberg H; Visser PJ
Journal article: ALZHEIMERS & DEMENTIA. 2018;14(7S_Part_3):p201
F1‐02‐01: RELATING CSF MARKERS NEUROGRANIN, NEUROFILAMENT‐LIGHT AND YKL‐40 TO Aβ, APOE ε4 AND COGNITION: RESULTS FROM THE EMIF‐AD MULTIMODAL BIOMARKER DISCOVERY STUDY
Bos I; Vos SJB; Verhey FRJ; Scheltens P; Engelborghs S; Frisoni GB; Blin O; Richardson J; Bordet R; Tsolaki M; Popp J; Martinez-Lage P; Lleó A; Johannsen P; Freund-Levi Y; Frölich L; Vandenberghe R; Baird AL; Barkhof F; Legido-Quigley C; Bertram L; Lovestone S; Streffer J; Andreasson U; Blennow K; Visser PJ; Zetterberg H
Article: ALZHEIMERS & DEMENTIA. 2018;14(7):913-924
Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease
Mattsson N; Groot C; Jansen WJ; Landau SM; Villemagne VL; Engelborghs S; Mintun MM; Lleo A; Molinuevo JL; Jagust WJ; Frisoni GB; Ivanoiu A; Chetelat G; de Oliveira CR; Rodrigue KM; Kornhuber J; Wallin A; Klimkowicz-Mrowiec A; Kandimalla R; Popp J; Aalten PP; Aarsland D; Alcolea D; Almdahl IS; Baldeiras I; van Buchem MA; Cavedo E; Chen K; Cohen AD; Foerster S; Fortea J; Frederiksen KS; Freund-Levi Y; Gill KD; Gkatzima O; Grimmer T; Hampel H; Herukka S-K; Johannsen P; van Laere K; de Leon MJ; Maier W; Marcusson J; Meulenbroek O; Mollergard HM; Morris JC; Mroczko B; Nordlund A; Prabhakar S; Peters O; Rami L; Rodriguez-Rodriguez E; Roe CM; Ruther E; Santana I; Schroder J; Seo SW; Soininen H; Spiru L; Stomrud E; Struyfs H; Teunissen CE; Verhey FRJ; Vos SJB; van Doorn LJCVW; Waldemar G; Wallin AK; Wiltfang J; Vandenberghe R; Brooks DJ; Fladby T; Rowe CC; Drzezga A; Verbeek MM; Sarazin M; Wolk DA; Fleisher AS; Klunk WE; Na DL; Sanchez-Juan P; Lee DY; Nordberg A; Tsolaki M; Camus V; Rinne JO; Fagan AM; Zetterberg H; Blennow K; Rabinovici GD; Hansson O; van Berckel BNM; van der Flier WM; Scheltens P; Visser PJ; Ossenkoppele R
Article: FRONTIERS IN AGING NEUROSCIENCE. 2018;10:193
Amyloid-β, Tau, and Cognition in Cognitively Normal Older Individuals: Examining the Necessity to Adjust for Biomarker Status in Normative Data
Bos I; Vos SJB; Jansen WJ; Vandenberghe R; Gabel S; Estanga A; Ecay-Torres M; Tomassen J; den Braber A; Lleo A; Sala I; Wallin A; Kettunen P; Molinuevo JL; Rami L; Chetelat G; de la Sayette V; Tsolaki M; Freund-Levi Y; Johannsen P; Novak GP; Ramakers I; Verhey FR; Visser PJ
Article: JAMA PSYCHIATRY. 2018;75(1):84-95
Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia
Jansen WJ; Ossenkoppele R; Tijms BM; Fagan AM; Hansson O; Klunk WE; van der Flier WM; Villemagne VL; Frisoni GB; Fleisher AS; Lleo A; Mintun MA; Wallin A; Engelborghs S; Na DL; Chetelat G; Molinuevo JL; Landau SM; Mattsson N; Kornhuber J; Sabri O; Rowe CC; Parnetti L; Popp J; Fladby T; Jagust WJ; Aalten P; Lee DY; Vandenberghe R; de Oliveira CR; Kapaki E; Froelich L; Ivanoiu A; Gabryelewicz T; Verbeek MM; Sanchez-Juan P; Hildebrandt H; Camus V; Zboch M; Brooks DJ; Drzezga A; Rinne JO; Newberg A; de Mendonca A; Sarazin M; Rabinovici GD; Madsen K; Kramberger MG; Nordberg A; Mok V; Mroczko B; Wolk DA; Meyer PT; Tsolaki M; Scheltens P; Verhey FRJ; Visser PJ
Article: ALZHEIMERS RESEARCH & THERAPY. 2017;9(1):101
Cerebrovascular and amyloid pathology in predementia stages: the relationship with neurodegeneration and cognitive decline
Bos I; Verhey FR; Ramakers IHGB; Jacobs HIL; Soininen H; Freund-Levi Y; Hampel H; Tsolaki M; Wallin AK; van Buchem MA; Oleksik A; Verbeek MM; Rikkert MO; van der Flier WM; Scheltens P; Aalten P; Visser PJ; Vos SJB
Article: JOURNAL OF ALZHEIMERS DISEASE. 2017;61(2):515-519
Does Fatty Acid Composition in Subcutaneous Adipose Tissue Differ between Patients with Alzheimer's Disease and Cohabiting Proxies?
Faxen-Irving G; Falahati F; Basun H; Eriksdotter M; Vedin I; Wahlund L-O; Schultzberg M; Hjorth E; Palmblad J; Cederholm T; Freund-Levi Y
Article: LANCET NEUROLOGY. 2017;16(12):965-975
24-month intervention with a specific multinutrient in people with prodromal Alzheimer's disease (LipiDiDiet): a randomised, double-blind, controlled trial
Soininen H; Solomon A; Visser PJ; Hendrix SB; Blennow K; Kivipelto M; Hartmann T
Article: JOURNAL OF ALZHEIMERS DISEASE. 2017;60(4):1387-1395
Association Between Later Life Lifestyle Factors and Alzheimer's Disease Biomarkers in Non-Demented Individuals: A Longitudinal Descriptive Cohort Study
Reijs BLR; Vos SJB; Soininen H; Lotjonen J; Koikkalainen J; Pikkarainen M; Hall A; Vanninen R; Liu Y; Herukka S-K; Freund-Levi Y; Frisoni GB; Frolich L; Nobilij F; Rikkert MO; Spiru L; Tsolaki M; Wallinn AK; Scheltens P; Verhey F; Visser PJ
Article: AMERICAN JOURNAL OF CLINICAL NUTRITION. 2017;106(4):1157-1165
DHA-rich n-3 fatty acid supplementation decreases DNA methylation in blood leukocytes: the OmegAD study
Karimi M; Vedin I; Levi YF; Basun H; Irving GF; Eriksdotter M; Wahlund L-O; Schultzberg M; Hjorth E; Cederholm T; Palmblad J
Article: ALZHEIMERS & DEMENTIA. 2017;13(8):903-912
Predicting progression to dementia in persons with mild cognitive impairment using cerebrospinal fluid markers
Handels RLH; Vos SJB; Kramberger MG; Jelic V; Blennow K; van Buchem M; van der Flier W; Freund-Levi Y; Hampel H; Rikkert MO; Oleksik A; Pirtosek Z; Scheltens P; Soininen H; Teunissen C; Tsolaki M; Wallin AK; Winblad B; Verhey FRJ; Visser PJ
Article: NEUROBIOLOGY OF AGING. 2017;56:33-40
The frequency and influence of dementia risk factors in prodromal Alzheimer's disease
Bos I; Vos SJ; Froelich L; Kornhuber J; Wiltfang J; Maier W; Peters O; Ruether E; Engelborghs S; Niemantsverdriet E; De Roeck EE; Tsolaki M; Freund-Levim Y; Johannsen P; Vandenberghe R; Lleo A; Alcolea D; Frisoni GB; Galluzzi S; Nobili F; Morbelli S; Drzezga A; Didic M; van Berckel BN; Salmon E; Bastin C; Dauby S; Santana I; Baldeiras I; de Mendonca A; Silva D; Wallin A; Nordlund A; Coloma PM; Wientzek A; Alexander M; Novak GP; Gordon MF; Wallin AK; Hampel H; Soininen H; Herukka S-K; Scheltens P; Verhey FR; Visser PJ
Journal article: ALZHEIMERS & DEMENTIA. 2017;13(7S_Part_22):p1047-p1048
[P3–273]: EFFECTS OF RISPERIDONE AND GALANTAMINE TREATMENT ON ALZHEIMER BIOMARKER LEVELS IN CEREBROSPINAL FLUID
Bloniecki V; Freund‐Levi Y; Blennow K; Aarsland D; Cummings JL; Winblad B
Article: JOURNAL OF ALZHEIMERS DISEASE. 2017;57(2):387-393
Effects of Risperidone and Galantamine Treatment on Alzheimer's Disease Biomarker Levels in Cerebrospinal Fluid
Bloniecki V; Aarsland D; Blennow K; Cummings J; Falahati F; Winblad B; Freund-Levi Y
Article: JOURNAL OF ALZHEIMERS DISEASE. 2017;56(2):543-555
Improved Cerebrospinal Fluid-Based Discrimination between Alzheimer's Disease Patients and Controls after Correction for Ventricular Volumes
van Doorn LJCVW; Gispert JD; Kuiperij HB; Claassen JAHR; Arighi A; Baldeiras I; Blennow K; Bozzali M; Castelo-Branco M; Cavedo E; Emek-Savas DD; Eren E; Eusebi P; Farotti L; Fenoglio C; Ormaechea JF; Freund-Levi Y; Frisoni GB; Galimberti D; Genc S; Greco V; Hampel H; Herukka S-K; Liu Y; Llado A; Lleo A; Nobili FM; Oguz KK; Parnetti L; Pereira J; Picco A; Pikkarainen M; de Oliveira CR; Saka E; Salvadori N; Sanchez-Valle R; Santana I; Scarpini E; Scheltens P; Soininen H; Tarducci R; Teunissen C; Tsolaki M; Urbani A; Vilaplana E; Visser PJ; Wallin AK; Yener G; Molinuevo JL; Meulenbroek O; Verbeek MM
Journal article: ALZHEIMERS & DEMENTIA. 2016;12(7S_Part_22):p1059-p1061
P4‐122: Prevalence of Vascular Risk Factors in Different Stages of Prodromal Alzheimer’s Disease and Its Influence on Cognitive Decline
Bos I; Vos SJB; Frölich L; Kornhuber J; Wiltfang J; Maier W; Peters O; Rüther E; Engelborghs S; Niemantsverdriet E; De Roeck EE; Tsolaki M; Freund-Levi Y; Johannsen P; Vandenberghe R; Lleó A; Alcolea D; Frisoni GB; Galluzzi S; Nobili F; Morbelli S; Drzezga A; Didic M; van Berckel BNM; Salmon E; Bastin C; Dauby S; Santana I; Baldeiras I; Mendonça A; Silva D; Wallin A; Nordlund A; Foskett N; Coloma P; Alexander M; Wientzek-Fleischmann A; Nevado-Holgado A; Gungabissoon U; Novak GP; Gordon MF; Wallin ÅK; Hampel H; Soininen H; Scheltens P; Verhey FRJ; Visser PJ
Article: JOURNAL OF ALZHEIMERS DISEASE. 2015;48(3):805-812
Plasma Fatty Acid Profiles in Relation to Cognition and Gender in Alzheimer's Disease Patients During Oral Omega-3 Fatty Acid Supplementation: The OmegAD Study
Eriksdotter M; Vedin I; Falahati F; Freund-Levi Y; Hjorth E; Faxen-Irving G; Wahlund L-O; Schultzberg M; Basun H; Cederholm T; Palmblad J
Journal article: CLINICAL NUTRITION. 2015;34:s245-s246
SUN-LB030: Does Fatty Acid Composition in Subcutaneous Fat Differ Between Patients With Alzheimer’s Disease and their Cohabiting Relatives?
Faxen-Irving G; Falahati F; Basun H; Palmblad J; Cederholm T; Vedin I; Eriksdotter M; Wahlund L-O; Schultzberg M; Hjorth E; Freund-Levi Y
Journal article: CLINICAL NUTRITION. 2015;34:s247-s248
SUN-LB035: Does APOE4 Carriership Influence Potential Omega-3 Fatty Acid Treatment Effects on Cognition or Psychiatric Status in Patients With Mild to Moderate Alzheimer’S Disease: The Omegad Study
Freund-Levi Y; Falahati F; Hjorth E; Cederholm T; Eriksdotter M; Vedin I; Faxen-Irving G; Wahlund L-O; Schultzberg M; Basun H; Palmblad J
Article: JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION. 2015;313(19):1924-1938
Prevalence of Cerebral Amyloid Pathology in Persons Without Dementia A Meta-analysis
Jansen WJ; Ossenkoppele R; Knol DL; Tijms BM; Scheltens P; Verhey FRJ; Visser PJ
Article: BRAIN. 2015;138(Pt 5):1327-1338
Prevalence and prognosis of Alzheimer's disease at the mild cognitive impairment stage
Vos SJB; Verhey F; Froelich L; Kornhuber J; Wiltfang J; Maier W; Peters O; Ruether E; Nobili F; Morbelli S; Frisoni GB; Drzezga A; Didic M; van Berckel BNM; Simmons A; Soininen H; Kloszewska I; Mecocci P; Tsolaki M; Vellas B; Lovestone S; Muscio C; Herukka S-K; Salmon E; Bastin C; Wallin A; Nordlund A; de Mendonca A; Silva D; Santana I; Lemos R; Engelborghs S; Van der Mussele S; Freund-Levi Y; Wallin AK; Hampel H; van der Flier W; Scheltens P; Visser PJ
Article: JOURNAL OF LIPID RESEARCH. 2015;56(3):674-681
Effects of n-3 FA supplementation on the release of proresolving lipid mediators by blood mononuclear cells: the OmegAD study
Wang X; Hjorth E; Vedin I; Eriksdotter M; Freund-Levi Y; Wahlund L-O; Cederholm T; Palmblad J; Schultzberg M
Article: CURRENT ALZHEIMER RESEARCH. 2015;12(1):69-79
Predicting Progression from Cognitive Impairment to Alzheimer's Disease with the Disease State Index
Hall A; Mattila J; Koikkalainen J; Loejonen J; Wolz R; Scheltens P; Frisoni G; Tsolaki M; Nobili F; Freund-Levi Y; Minthon L; Froelich L; Hampel H; Visser PJ; Soininen H
Article: JOURNAL OF ALZHEIMERS DISEASE. 2014;42(3):823-831
Effects of Supplementation with Omega-3 Fatty Acids on Oxidative Stress and Inflammation in Patients with Alzheimer's Disease: The OmegAD Study
Freund-Levi Y; Vedin I; Hjorth E; Basun H; Irving GF; Schultzberg M; Eriksdotter M; Palmblad J; Vessby B; Wahlund L-O; Cederholm T; Basu S
Article: BRAIN RESEARCH BULLETIN. 2014;108:88-93
Neuropsychiatric symptoms in dementia-A role for neuroinflammation?
Holmgren S; Hjorth E; Schultzberg M; Larksater M; Frenkel D; Tysen-Backstrom AC; Aarsland D; Freund-Levi Y
Journal article: ALZHEIMERS & DEMENTIA. 2014;10(4S_Part_4):p265
O4‐07‐05: ADDED VALUE OF MRI BIOMARKERS TO NEUROPSYCHOLOGICAL TEST PERFORMANCE FOR PREDICTION OF AD IN SUBJECTS WITH MCI
Clerx L; Dierckx E; van der Pol L; van Rossum I; Verhey FRJ; Aalten P; Barkhof F; Wolz R; Rueckert D; Frisoni G; Tsolaki M; Nobili F; Freund‐Levi Y; Wallin AK; Frolich L; Hampel HJ; Soininen H; Scheltens P; Visser PJ
Journal article: ALZHEIMERS & DEMENTIA. 2014;10(4S_Part_11):p455
P1‐384: EFFECTS OF OMEGA‐3 FATTY ACID SUPPLEMENTATION ON PLASMA FATTY ACIDS, GENDER EFFECTS, AND EFFECTS ON COGNITION IN ALZHEIMER'S PATIENTS: THE OMEGAD STUDY
Eriksdotter M; Falahati F; Vedin I; Freund‐Levi Y; Hjorth E; Faxen‐Irving G; Wahlund L; Schultzberg M; Basun H; Cederholm T; Palmblad J
Article: DEMENTIA AND GERIATRIC COGNITIVE DISORDERS EXTRA. 2014;4(2):335-343
Agitation in dementia: relation to core cerebrospinal fluid biomarker levels.
Bloniecki V; Aarsland D; Cummings J; Blennow K; Freund-Levi Y
Article: AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY. 2014;22(4):341-348
Galantamine Versus Risperidone Treatment of Neuropsychiatric Symptoms in Patients with Probable Dementia: An Open Randomized Trial
Freund-Levi Y; Jedenius E; Tysen-Backstrom AC; Larksater M; Wahlund L-O; Eriksdotter M
Article: JOURNAL OF INTERNAL MEDICINE. 2014;275(4):428-436
Transfer of omega-3 fatty acids across the blood-brain barrier after dietary supplementation with a docosahexaenoic acid-rich omega-3 fatty acid preparation in patients with Alzheimer's disease: the OmegAD study
Levi YF; Vedin I; Cederholm T; Basun H; Irving GF; Eriksdotter M; Hjorth E; Schultzberg M; Vessby B; Wahlund L-O; Salem NJ; Palmblad J
Article: DEMENTIA AND GERIATRIC COGNITIVE DISORDERS. 2014;38(3-4):234-244
Galantamine versus Risperidone for Agitation in People with Dementia: A Randomized, Twelve-Week, Single-Center Study
Freund-Levi Y; Bloniecki V; Auestad B; Backstrom ACT; Larksater M; Aarsland D
Journal article: ALZHEIMERS & DEMENTIA. 2013;9(4S_Part_17):p669-p670
P3–306: A randomized controlled trial investigating the effects of Souvenaid in prodromal Alzheimer's disease: Baseline characteristics of the LipiDiDiet study
Visser PJ; Soininen H; Kivipelto M; Freund‐Levi Y; Kamphuis P; Wieggers RL; Hartmann T
Article: JOURNAL OF ALZHEIMERS DISEASE. 2013;36(1):1-6
Effects on Transthyretin in Plasma and Cerebrospinal Fluid by DHA-Rich n-3 Fatty Acid Supplementation in Patients with Alzheimer's Disease: The OmegAD Study
Faxen-Irving G; Freund-Levi Y; Eriksdotter-Jonhagen M; Basun H; Hjorth E; Palmblad J; Vedin I; Cederholm T; Wahlund L-O
Article: JOURNAL OF ALZHEIMERS DISEASE. 2013;35(4):697-713
Omega-3 Fatty Acids Enhance Phagocytosis of Alzheimer's Disease-Related Amyloid-β₄₂ by Human Microglia and Decrease Inflammatory Markers
Hjorth E; Zhu M; Toro VC; Vedin I; Palmblad J; Cederholm T; Freund-Levi Y; Faxen-Irving G; Wahlund L-O; Basun H; Eriksdotter M; Schultzberg M
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2013;40(4):580-593
Low background and high contrast PET imaging of amyloid-β with [¹¹C]AZD2995 and [¹¹C]AZD2184 in Alzheimer's disease patients
Forsberg A; Jureus A; Cselenyi Z; Eriksdotter M; Freund-Levi Y; Jeppsson F; Swahn B-M; Sandell J; Julin P; Schou M; Andersson J; Johnstrom P; Varnas K; Halldin C; Farde L; Svensson S
Journal article: ALZHEIMERS & DEMENTIA. 2012;8(4S_Part_16):p602
P3‐419: The LipiDiDiet study: Rationale and study design
Freund‐Levi Y; Visser PJ; Kivipelto M; Wieggers RL; Hartmann T; Soininen H
Article: PLOS ONE. 2012;7(4):e35425
Effects of DHA- Rich n-3 Fatty Acid Supplementation on Gene Expression in Blood Mononuclear Leukocytes: The OmegAD Study
Vedin I; Cederholm T; Freund-Levi Y; Basun H; Garlind A; Irving GF; Eriksdotter-Jonhagen M; Wahlund L-O; Dahlman I; Palmblad J
Journal article: CLINICAL NUTRITION. 2011;6(1):9
OP020 OXIDATIVE STRESS AND COX-MEDIATED INFLAMMATION IN PATIENTS WITH ALZHEIMER'S DISEASE AND EFFECTS OF N-3 FATTY ACID SUPPLEMENTATION – THE OMEGAD STUDY
Freund-Levi Y; Cederholm T; Basu S; group OBOOS
Article: AMERICAN JOURNAL OF ALZHEIMERS DISEASE AND OTHER DEMENTIAS. 2010;25(6):521-526
To Be a Good Food Provider: An Exploratory Study Among Spouses of Persons With Alzheimer's Disease
Fjellstrom C; Starkenberg A; Wesslen A; Licentiate MS; Backstrom A-CT; Faxen-Irving G
Article: JOURNAL OF LIPID RESEARCH. 2010;51(5):1179-1185
Reduced prostaglandin F_2α release from blood mononuclear leukocytes after oral supplementation of ω3 fatty acids: the OmegAD study
Vedin I; Cederholm T; Freund-Levi Y; Basun H; Hjorth E; Irving GF; Eriksdotter-Jonhagen M; Schultzberg M; Wahlund L-O; Palmblad J
Journal article: EUROPEAN PSYCHIATRY. 2010;25(S1):1595
PW01-263 - Galantamine compared to risperidone in neuropsychiatric and behavioural symptoms in Alzheimer patients: a one-center clinical trial in 100 patients
Freund-Levi Y; Wahlund L-O; Eriksdotter-Jönhagen M
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2009;36(11):1859-1863
Detection of amyloid in Alzheimer's disease with positron emission tomography using [¹¹C]AZD2184
Nyberg S; Jonhagen ME; Cselenyi Z; Halldin C; Julin P; Olsson H; Freund-Levi Y; Andersson J; Varnas K; Svensson S; Farde L
Journal article: ALZHEIMERS & DEMENTIA. 2009;5(4S_Part_3):p97
F2‐01‐01: Why Alzheimer patients and caregivers participate in randomized clinical trials
Akenine U; Andreasen N; Freund‐Levi Y; Winblad B; Kivipelto M
Article: LANCET NEUROLOGY. 2009;8(7):619-627
Prevalence and prognostic value of CSF markers of Alzheimer's disease pathology in patients with subjective cognitive impairment or mild cognitive impairment in the DESCRIPA study: a prospective cohort study
Visser PJ; Verhey F; Knol DL; Scheltens P; Wahlund L-O; Freund-Levi Y; Tsolaki M; Minthon L; Wallin AK; Hampel H; Buerger K; Pirttila T; Soininen H; Rikkert MO; Verbeek MM; Spiru L; Blennow K
Article: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 2009;57(1):11-17
Omega-3 Fatty Acid Supplementation Effects on Weight and Appetite in Patients with Alzheimer's Disease: The Omega-3 Alzheimer's Disease Study
Irving GF; Freund-Levi Y; Eriksdotter-Joenhagen M; Basun H; Brismar K; Hjorth E; Palmblad J; Vessby B; Vedin I; Wahlund L-O; Cederholm T
Article: DEMENTIA AND GERIATRIC COGNITIVE DISORDERS. 2009;27(5):481-490
Effects of Omega-3 Fatty Acids on Inflammatory Markers in Cerebrospinal Fluid and Plasma in Alzheimer's Disease: The OmegAD Study
Freund-Levi Y; Hjorth E; Lindberg C; Cederholm T; Faxen-Irving G; Vedin I; Palmblad J; Wahlund L-O; Schultzberg M; Basun H; Jonhagen ME
Journal article: CLINICAL NUTRITION. 2009;4(2):20
O043 EFFECTS OF A DHA RICH N-3 FATTY ACID SUPPLEMENTATION ON GENE EXPRESSION CHANGES IN BLOOD LEUKOCYTES: THE OMEGAD STUDY
Vedin I; Cederholm T; Freund-Levi Y; Basun H; Garlind A; Faxén-Irving G; Jönhagen ME; Wahlund L; Dahlman I; Palmblad J
Article: AMERICAN JOURNAL OF CLINICAL NUTRITION. 2008;87(6):1616-1622
Effects of docosahexaenoic acid-rich n-3 fatty acid supplementation on cytokine release from blood mononuclear leukocytes: the OmegAD study
Vedin I; Cederholm T; Levi YF; Basun H; Garlind A; Irving GF; Joenhagen ME; Vessby B; Wahlund L-O; Palmblad J
Article: INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY. 2008;23(2):161-169
Omega-3 supplementation in mild to moderate Alzheimer's disease:: effects on neuropsychiatric symptoms
Freund-Levi Y; Basun H; Cederholm T; Faxen-Irving G; Garlind A; Grut M; Vedin I; Palmblad J; Wahlund L-O; Eriksdotter-Jonhagen M
Article: ARCHIVES OF NEUROLOGY. 2006;63(10):1402-1408
ω-3 fatty acid treatment in 174 patients with mild to moderate Alzheimer disease:: OmegAD study -: A randomized double-blind trial
Freund-Levi Y; Eriksdotter-Jonhagen M; Cederholm T; Basun H; Faxen-Irving G; Garlind A; Vedin I; Vessby B; Wahlund L-O; Palmblad J
Journal article: ALZHEIMERS & DEMENTIA. 2006;2(3S_Part_3):s64
O3–05–08: A randomized double–blind trial with omega–3 fatty acid treatment in mild to moderate Alzheimer's disease
Freund-Levi Y; Jonhagen ME; Cederholm T; Basun H; Faxen-Irving G; Garlind A; Vedin I; Vessby B; Wahlund L-O; Palmblad J
Journal article: ALZHEIMERS & DEMENTIA. 2006;2(3S_Part_9):s271-s272
P2–130: Correlation of inflammatory factors with Alzheimer biomarkers
Schultzberg M; Freund-Levi Y; Garlind A; Cederholm T; Palmblad J; Wahlund L-O; Eriksdotter-Jonhagen M; Basun H
Journal article: LAKARTIDNINGEN. 1991;88(5):310-312
[Light therapy of depression].
Wetterberg L; Kjellman B; Thalén BE; Beck-Friis J; Freund-Levi Y; Friberg Y; Nordlund AL; Björkstén KS; Wiberg B; Zettergren M
Journal article: MAGNETIC RESONANCE IMAGING. 1989;7(2):225-230
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Preprint: MEDRXIV. 2021
Sex-specific metabolic pathways associate with Alzheimer’s Disease (AD) endophenotypes in the European Medical Information Framework for AD Multimodal Biomarker Discovery cohort
Xu J; Green R; Kim M; Lord J; Ebshiana A; Westwood S; Baird AL; Nevado-Holgado AJ; Shi L; Hye A; Snowden SG; Bos I; Vos SJB; Vandenberghe R; Teunissen CE; Kate MT; Scheltens P; Gabel S; Meersmans K; Blin O; Richardson J; De Roeck EE; Engelborghs S; Sleegers K; Bordet R; Rami L; Kettunen P; Tsolaki M; Verhey FRJ; Alcolea D; Lleó A; Peyratout G; Tainta M; Johannsen P; Freund-Levi Y; Frölich L; Dobricic V; Frisoni GB; Molinuevo JL; Wallin A; Popp J; Martinez-Lage P; Bertram L; Blennow K; Zetterberg H; Streffer J; Visser PJ; Lovestone S; Proitsi P; Legido-Quigley C
Conference publication: EUROPEAN PSYCHIATRY. 2021;64:S690
Physical training for patients with depression and anxiety - a randomized controlled study
Zhai Q; Freund-Levi Y; Horn A; Fridenberger A-C; Lager E; Montgomery S; Persson J
Preprint: MEDRXIV. 2020;MEDRXIV
Cerebrospinal fluid total tau levels indicate aberrant neuronal plasticity in Alzheimer's disease.
Visser PJ; Reus LM; Gobom J; Jansen I; Dicks E; Tsolaki M; Verhey FRJ; Popp J; Martinez-Lage P; Vandenberghe R; Lleó A; Molinuevo JL; Engelborghs S; Freund-Levi Y; Froelich L; Sleegers K; Dobricic V; Hong S; Lovestone S; Streffer J; Vos SJB; Bos I; Smit AB; Blennow K; Scheltens P; Teunissen CE; Bertram L; Zetterberg H; Tijms BM
Review: ALZHEIMER'S AND DEMENTIA: TRANSLATIONAL RESEARCH AND CLINICAL INTERVENTIONS. 2020;6(1):e12016
Agitation and impulsivity in mid and late life as possible risk markers for incident dementia
Bateman DR; Gill S; Hu S; Foster ED; Ruthirakuhan MT; Sellek AF; Mortby ME; Matuskova V; Ng KP; Tarawneh RM; Freund-Levi Y; Kumar S; Gauthier S; Rosenberg PB; de Oliveira FF; Devanand DP; Ballard C; Ismail Z
Preprint: RESEARCH SQUARE. 2019
Antipsychotic Drugs Attenuate Interleukin-6 Secretion by Microglia Via Dopamine Inhibition
Mekori-Domachevsky E; Nash Y; Rabinovich A; Frenkel D; Freund-Levi Y
Preprint: MEDRXIV. 2019
A metabolite-based machine learning approach to diagnose Alzheimer’s-type dementia in blood: Results from the European Medical Information Framework for Alzheimer’s Disease biomarker discovery cohort
Stamate D; Kim M; Proitsi P; Westwood S; Baird A; Nevado-Holgado A; Hye A; Bos I; Vos S; Vandenberghe R; Teunissen CE; Kate MT; Scheltens P; Gabel S; Meersmans K; Blin O; Richardson J; De Roeck E; Engelborghs S; Sleegers K; Bordet R; Rami L; Kettunen P; Tsolaki M; Verhey F; Alcolea D; Lléo A; Peyratout G; Tainta M; Johannsen P; Freund-Levi Y; Frölich L; Dobricic V; Frisoni GB; Molinuevo JL; Wallin A; Popp J; Martinez-Lage P; Bertram L; Blennow K; Zetterberg H; Streffer J; Visser PJ; Lovestone S; Legido-Quigley C
Preprint: SSRN ELECTRONIC JOURNAL. 2019
Biomarker Based and Individualized Prognosis for Patients with Mild Cognitive Impairment: Towards a Personalized Medicine Approach for AD
van Maurik I; Bos I; Vos SJ; Bouwman FH; Teunissen CE; Scheltens P; Barkhof F; Frolich L; Kornhuber J; Wiltfang J; Maier W; Peters O; Ruther E; Nobili F; Frisoni G; Spiru L; Freund-Levi Y; Wallin AK; Hampel H; Soininen H; Tsolaki M; Verhey F; Simmons A; Kloszewska I; Mecocci P; Vellas B; Lovestone S; Galluzzi S; Herukka S-K; Santana I; Baldeiras I; de Mendonça A; Silva D; Chetelat G; Egret S; Palmqvist S; Hansson O; Visser P-J; Initiative ADN; Berkhof J; van der Flier WM
Corrigendum: ALZHEIMERS RESEARCH & THERAPY. 2018;10(1):56
Cerebrovascular and amyloid pathology in predementia stages: the relationship with neurodegeneration and cognitive decline (vol 9, 101, 2017)
Bos I; Verhey FR; Ramakers IHGB; Jacobs HIL; Soininen H; Freund-Levi Y; Hampel H; Tsolaki M; Wallin AK; van Buchem MA; Oleksik A; Verbeek MM; Rikkert MO; van der Flier WM; Scheltens P; Aalten P; Visser PJ; Vos SJB
Review: ADVANCES IN NUTRITION. 2017;8(1):17-26
Nutritional Considerations for Healthy Aging and Reduction in Age-Related Chronic Disease
Shlisky J; Bloom DE; Beaudreault AR; Tucker KL; Keller HH; Freund-Levi Y; Fielding RA; Cheng FW; Jensen GL; Wu D; Meydani SN
Letter: AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY. 2014;22(9):951
Galantamine Versus Risperidone Treatment of Neuropsychiatric Symptoms in Patients with Probable Dementia: An Open Randomized Trial Response
Freund-Levi Y; Jedenius E; Wahlund L-O; Eriksdotter M; Tysen-Backstrom AC; Larksater M
Review: CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE. 2012;15(2):134-143
Immunomodulation of microglia by docosahexaenoic acid and eicosapentaenoic acid
Hjorth E; Freund-Levi Y
Conference publication: EUROPEAN JOURNAL OF NEUROLOGY. 2012;19:112
Agitation - relation to clinical and dementia biomarkers in cerebrospinal fluid
Bloniecki V; Freund-Levi Y; Aarsland D; Blennow K
Conference publication: EUROPEAN JOURNAL OF NEUROLOGY. 2012;19:112
Baseline characteristics of subjects with prodromal Alzheimer's disease: the LipiDiDiet study
Freund-Levi Y; Visser PJ; Kivipelto M; Kamphuis PJGH; Wieggers RL; Hartmann T; Soininen H
Conference publication: ANNALS OF NEUROLOGY. 2012;72:S53-S54
Baseline Characteristics of Subjects with Prodromal Alzheimer's Disease: The LipiDiDiet Study
Freund-Levi Y; Visser PJ; Kivipelto M; Wieggers RL; Hartmann T; Soininen H
Conference publication: EUROPEAN PSYCHIATRY. 2010;25
GALANTAMINE COMPARED TO RISPERIDONE IN NEUROPSYCHIATRIC AND BEHAVIOURAL SYMPTOMS IN ALZHEIMER PATIENTS: A ONE-CENTER CLINICAL TRIAL IN 100 PATIENTS
Freund-Levi Y; Wahlund L-O; Eriksdotter-Jonhagen M
Conference publication: FASEB JOURNAL. 2009;23:543.10
N-3 fatty acid treatment and plasma transthyretin in patients with Alzheimer's disease
Irving GF; Freund-Levi Y; Eriksdotter-Jonhagen M; Basun H; Palmblad J; Vedin I; Wahlund L-O; Cederholm T
Corrigendum: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 2009;57(3):579
Omega Fatty Acid Supplementation Effects on Weight and Appetite in Patients with Alzheimer's Disease: The Omega-3 Alzheimer's Disease Study (vol 57, pg 11, 2009)
Irving GF; Freund-Levi Y
Thesis / dissertation: 2008
Omega-3 fatty acid treatment in mild to moderate Alzheimer's disease : results from the OmegAD study
Freund-Levi, Yvonne
Review: LAKARTIDNINGEN. 2007;104(44):3268-3271
[Omega-3-fatty acids protect against dementia. Also early symptoms of mild Alzheimer disease seem to be inhibited].
Palmblad J; Eriksdotter-Jönhagen M; Freund-Levi Y; Cederholm T
Review: LAKARTIDNINGEN. 2006;103(6):369-371
[Administration of symptom-relieving drugs in Alzheimer disease is beneficial].
Nordberg A; Eriksdotter-Jönhagen M; Garlind A; Grut M; Freund-Levi Y; Cornelius C; Ekström A; Fastbom J; Sedvall M; Viitanen M
Meeting abstract: NEUROBIOLOGY OF AGING. 2004;25:S471
Safety and tolerability of omega-3 fatty acids in patients with Alzheimers disease
Freund-Levi Y; Jonhagen ME; Wahlund LO; Basun H; Palmblad J; Cederholm T
Conference publication: FASEB JOURNAL. 2004;18(4):A501
Inflammatory gene expression changes by omega-3 fatty acids in patients with Alzheimer's disease
Vedin I; Cederholm T; Lidén J; Freund-Levi Y; Palmblad J
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Forskningsbidrag

Rehabilitation profile for post COVID-19 patients
Swedish Research Council for Environment Agricultural Sciences and Spatial Planning
1 November 2020 - 31 October 2021

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Lektor/Överläkare, Klinisk forskning och utbildning, Södersjukhuset, Karolinska Institutet, 2022-

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Docent, Klinisk neurovetenskap, Karolinska Institutet, 2015
Medicine Doktorsexamen, Institutionen för neurobiologi, vårdvetenskap och samhälle, Karolinska Institutet, 2008

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