Xiao-Wei Zheng

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: BRITISH JOURNAL OF PHARMACOLOGY. 2024;182(2):417-431
miR-210 as a therapeutic target in diabetes-associated endothelial dysfunction
Collado A; Jiao T; Kontidou E; Carvalho LRRA; Chernogubova E; Yang J; Zaccagnini G; Zhao A; Tengbom J; Zheng X; Rethi B; Alvarsson M; Catrina S-B; Mahdi A; Carlstroem M; Martelli F; Pernow J; Zhou Z
Article: EMBO REPORTS. 2024;25(4):1752-1772
Appropriate glycemic management protects the germline but not the uterine environment in hyperglycemia
Zhao A; Jiang H; Palomares AR; Larsson A; He W; Grunler J; Zheng X; Wallberg KAR; Catrina S-B; Deng Q
Article: EMBO MOLECULAR MEDICINE. 2024;16(3):596-615
Rare coding variants in NOX4 link high ROS levels to psoriatic arthritis mutilans
Wang S; Nikamo P; Laasonen L; Gudbjornsson B; Ejstrup L; Iversen L; Lindqvist U; Alm JJ; Eisfeldt J; Zheng X; Catrina S-B; Taylan F; Vaz R; Stahle M; Tapia-Paez I
Article: ANTIOXIDANTS. 2023;12(12):2043
Comparing the Blood Response to Hyperbaric Oxygen with High-Intensity Interval Training-A Crossover Study in Healthy Volunteers
Kjellberg A; Lindholm ME; Zheng X; Liwenborg L; Rodriguez-Wallberg KA; Catrina S-B; Lindholm P
Article: JOURNAL OF CLINICAL INVESTIGATION. 2023;133(17):e167693
Hypoxic erythrocytes mediate cardioprotection through activation of soluble guanylate cyclase and release of cyclic GMP
Yang J; Sundqvist ML; Zheng X; Jiao T; Collado A; Tratsiakovich Y; Mahdi A; Tengbom J; Mergia E; Catrina S-B; Zhou Z; Carlstroem M; Akaike T; Cortese-Krott MM; Weitzberg E; Lundberg JO; Pernow J
Article: JOURNAL OF AUTOIMMUNITY. 2022;133:102903
Autoantibodies targeting malondialdehyde-modifications in rheumatoid arthritis regulate osteoclasts via inducing glycolysis and lipid biosynthesis
Sakuraba K; Krishnamurthy A; Sun J; Zheng X; Xu C; Peng B; Engstrom M; Jakobsson P-J; Wermeling F; Catrina S; Gronwall C; Catrina AI; Rethi B
Article: BMJ OPEN. 2022;12(11):e061870
Hyperbaric oxygen for treatment of long COVID-19 syndrome (HOT-LoCO): protocol for a randomised, placebo-controlled, double-blind, phase II clinical trial
Kjellberg A; Abdel-Halim L; Hassler A; El Gharbi S; Al-Ezerjawi S; Bostrom E; Sundberg CJ; Pernow J; Medson K; Kowalski JH; Rodriguez-Wallberg KA; Zheng X; Catrina S; Runold M; Stahlberg M; Bruchfeld J; Nygren-Bonnier M; Lindholm P
Article: MBIO. 2022;13(5):e0108622-e01022
High Glucose and Carbonyl Stress Impair HIF-1-Regulated Responses and the Control of Mycobacterium tuberculosis in Macrophages
Teran G; Li H; Catrina S-B; Liu R; Brighenti S; Zheng X; Grunler J; Nylen S; Carow B; Rottenberg ME
Article: ELIFE. 2022;11:e70714
Repression of hypoxia-inducible factor-1 contributes to increased mitochondrial reactive oxygen species production in diabetes
Zheng X; Narayanan S; Xu C; Eliasson Angelstig S; Grunler J; Zhao A; Di Toro A; Bernardi L; Mazzone M; Carmeliet P; Del Sole M; Solaini G; Forsberg EA; Zhang A; Brismar K; Schiffer TA; Rajamand Ekberg N; Botusan IR; Palm F; Catrina S-B
Article: DIABETES. 2022;71(2):285-297
Downregulation of Erythrocyte miR-210 Induces Endothelial Dysfunction in Type 2 Diabetes
Zhou Z; Collado A; Sun C; Tratsiakovich Y; Mahdi A; Winter H; Chernogubova E; Seime T; Narayanan S; Jiao T; Jin H; Alvarsson M; Zheng X; Yang J; Hedin U; Catrina S-B; Maegdefessel L; Pernow J
Article: BMJ OPEN. 2021;11(7):e046738
Randomised, controlled, open label, multicentre clinical trial to explore safety and efficacy of hyperbaric oxygen for preventing ICU admission, morbidity and mortality in adult patients with COVID-19
Kjellberg A; Douglas J; Pawlik MT; Kraus M; Oscarsson N; Zheng X; Bergman P; Franberg O; Kowalski JH; Nyren SP; Silvanius M; Skold M; Catrina S-B; Rodriguez-Wallberg KA; Lindholm P
Article: ANTIOXIDANTS. 2021;10(7):1070
Dehydro-Tocotrienol-β Counteracts Oxidative-Stress-Induced Diabetes Complications in db/db Mice
Dallner G; Bentinger M; Hussain S; Sinha I; Yang J; Schwank-Xu C; Zheng X; Swiezewska E; Brismar K; Valladolid-Acebes I; Tekle M
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2021;141(3):659-671
miR-19a/b and miR-20a Promote Wound Healing by Regulating the Inflammatory Response of Keratinocytes
Li D; Peng H; Qu L; Sommar P; Wang A; Chu T; Li X; Bi X; Liu Q; Serezal IG; Rollman O; Lohcharoenkal W; Zheng X; Angelstig SE; Grunler J; Pivarcsi A; Sonkoly E; Catrina S-B; Xiao C; Stahle M; Mi Q-S; Zhou L; Landen NX
Article: COMMUNICATIONS BIOLOGY. 2020;3(1):768
HypoxamiR-210 accelerates wound healing in diabetic mice by improving cellular metabolism
Narayanan S; Angelstig SE; Xu C; Grunler J; Zhao A; Zhu W; Landen NX; Stahle M; Zhang J; Ivan M; Maltesen RG; Botusan IR; Ekberg NR; Zheng X; Catrina S-B
Article: EBIOMEDICINE. 2019;44:489-501
Specific loss of adipocyte CD248 improves metabolic health via reduced white adipose tissue hypoxia, fibrosis and inflammation
Petrus P; Fernandez TL; Kwon MM; Huang JL; Lei V; Safikhan NS; Karunakaran S; O'Shannessy DJ; Zheng X; Catrina S-B; Albone E; Laine J; Virtanen K; Clee SM; Kieffer TJ; Noll C; Carpentier AC; Johnson JD; Ryden M; Conway EM
Article: JOURNAL OF DIABETES RESEARCH. 2019;2019:2936962-8
Protective Effect of the HIF-1A Pro582Ser Polymorphism on Severe Diabetic Retinopathy
Ekberg NR; Eliasson S; Li YW; Zheng X; Chatzidionysiou K; Falhammar H; Gu HF; Catrina S-B
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2019;116(14):6985-6994
Triggering of a Dll4-Notch1 loop impairs wound healing in diabetes
Zheng X; Narayanan S; Sunkari VG; Eliasson S; Botusan IR; Grunler J; Catrina AI; Radtke F; Xu C; Zhao A; Ekberg NR; Lendahl U; Catrina S-B
Article: JOURNAL OF VISUALIZED EXPERIMENTS. 2018;(138)
Co-immunoprecipitation Assay Using Endogenous Nuclear Proteins from Cells Cultured Under Hypoxic Conditions
Zheng X; Ho CQW; Zheng X; Lee KL; Gradin K; Pereira TS; Berggren P-O; Ali Y
Article: JACC: BASIC TO TRANSLATIONAL SCIENCE. 2018;3(4):450-463
Red Blood Cells in Type 2 Diabetes Impair Cardiac Post-Ischemic Recovery Through an Arginase-Dependent Modulation of Nitric Oxide Synthase and Reactive Oxygen Species
Yang J; Zheng X; Mahdi A; Zhou Z; Tratsiakovich Y; Jiao T; Kiss A; Kovamees O; Alvarsson M; Catrina S-B; Lundberg JO; Brismar K; Pernow J
Article: PLOS ONE. 2018;13(3):e0193084
Deficiency of liver-derived insulin-like growth factor-I (IGF-I) does not interfere with the skin wound healing rate
Botusan IR; Zheng X; Narayanan S; Grunler J; Sunkari VG; Calissendorff FS; Ansurudeen I; Illies C; Svensson J; Jansson J-O; Ohlsson C; Brismar K; Catrina S-B
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2017;137(12):2630-2638
MicroRNA-132 with Therapeutic Potential in Chronic Wounds
Li X; Li D; Wang A; Chu T; Lohcharoenkal W; Zheng X; Grunler J; Narayanan S; Eliasson S; Herter EK; Wang Y; Ma Y; Ehrstrom M; Eidsmo L; Kasper M; Pivarcsi A; Sonkoly E; Catrina S-B; Stahle M; Landen NX
Article: EXPERIMENTAL CELL RESEARCH. 2017;358(2):129-139
A Notch-independent mechanism contributes to the induction of Hes1 gene expression in response to hypoxia in P19 cells
Zheng X; Narayanan S; Zheng X; Luecke-Johansson S; Gradin K; Catrina S-B; Poellinger L; Pereira TS
Article: ACTA PHYSIOLOGICA. 2014;210(3):590-599
Adenosine increases LPS-induced nuclear factor kappa B activation in smooth muscle cells via an intracellular mechanism and modulates it via actions on adenosine receptors
Yang J; Zheng X; Haugen F; Dare E; Lovdahl C; Schulte G; Fredholm BB; Valen G
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2014;111(7):2560-2565
Hypoxia-induced and calpain-dependent cleavage of filamin A regulates the hypoxic response
Zheng X; Zhou A-X; Rouhi P; Uramoto H; Boren J; Cao Y; Pereira T; Akyurek LM; Poellinger L
Article: DIABETES CARE. 2013;36(2):415-421
Impact of the Hypoxia-Inducible Factor-1 α (HIF1A) Pro582Ser Polymorphism on Diabetes Nephropathy
Gu HF; Zheng X; Abu Seman N; Gu T; Botusan IR; Sunkari VG; Lokman EF; Brismar K; Catrina S-B
Article: CELL DEATH AND DISEASE. 2012;3(6):e322
Acute hypoxia induces apoptosis of pancreatic β-cell by activation of the unfolded protein response and upregulation of CHOP
Zheng X; Zheng X; Wang X; Ma Z; Sunkari VG; Botusan I; Takeda T; Bjorklund A; Inoue M; Catrina S-B; Brismar K; Poellinger L; Pereira TS
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2008;105(9):3368-3373
Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways
Zheng X; Linke S; Dias JM; Zheng X; Gradin K; Wallis TP; Hamilton BR; Gustafsson M; Ruas JL; Wilkins S; Bilton RL; Brismar K; Whitelaw ML; Pereira T; Gorman JJ; Ericson J; Peet DJ; Lendahl U; Poellinger L
Article: CELL CYCLE. 2006;5(23):2720-2722
Degradation of the hypoxia-inducible factor 1α -: Where does it happen?
Pereira T; Zheng X; Poellinger L
Article: MOLECULAR AND CELLULAR BIOLOGY. 2006;26(12):4628-4641
Cell-type-specific regulation of degradation of hypoxia-inducible factor 1α:: Role of subcellular compartmentalization
Zheng X; Ruas JL; Cao R; Salomons FA; Cao Y; Poellinger L; Pereira T
Article: DEVELOPMENTAL CELL. 2005;9(5):617-628
Hypoxia requires Notch signaling to maintain the undifferentiated cell state
Gustafsson MV; Zheng XW; Pereira T; Gradin K; Jin SB; Lundkvist J; Ruas JL; Poellinger L; Lendahl U; Bondesson M
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2003;278(9):6816-6823
Identification of residues critical for regulation of protein stability and the transactivation function of the hypoxia-inducible factor-1α by the von Hippel-Lindau tumor suppressor gene product
Pereira T; Zheng XW; Ruas JL; Tanimoto K; Poellinger L
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Corrigendum: JOURNAL OF DIABETES RESEARCH. 2021;2021:9827150-1
Protective Effect of the HIF-1A Pro582Ser Polymorphism on Severe Diabetic Retinopathy (vol 2019, 2936962, 2019)
Ekberg NR; Eliasson S; Li YW; Zheng X; Chatzidionysiou K; Falhammar H; Gu HF; Catrina S-B
Review: DIABETOLOGIA. 2021;64(4):709-716
Hypoxia and hypoxia-inducible factors in diabetes and its complications
Catrina S-B; Zheng X
Letter: CLINICAL AND TRANSLATIONAL MEDICINE. 2021;11(1):e273
Repressed hypoxia inducible factor-1 in diabetes aggravates pulmonary aspergillus fumigatus infection through modulation of inflammatory responses
Ye Y; Chen Y; Sun J; Zhang H; Li W; Wang W; Zheng X; Catrina S-B
Published conference paper: DIABETES/METABOLISM RESEARCH AND REVIEWS. 2016;32:179-185
Disturbed hypoxic responses as a pathogenic mechanism of diabetic foot ulcers
Catrina S-B; Zheng X
Editorial comment: ENDOCRINE. 2014;46(2):347-350
Selective blockade of estrogen receptor beta improves wound healing in diabetes
Sunkari VG; Botusan IR; Savu O; Grunler J; Zheng X; Gustafsson J-A; Brismar K; Catrina S-B

Anställningar

Senior Forskningsspecialist, Molekylär medicin och kirurgi, Karolinska Institutet, 2022-

Examina och utbildning

Medicine Doktorsexamen, Institutionen för cell- och molekylärbiologi, Karolinska Institutet, 2009

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