Xiao-Wei Zheng
Senior Research Specialist | Docent
E-mail: xiaowei.zheng@ki.se
Visiting address: Karolinska Institutet, BioClinicum J8:20, Visionsgatan 4, 17164 Solna
Postal address: K1 Molekylär medicin och kirurgi, K1 MMK Tillväxt & metabolism, 171 76 Stockholm
About me
I am a trained cardiologist, and I got my Ph.D. degree at the Department of Cell and Molecular Biology of Karolinska Institutet. Now I am working as Senior Research Specialist at the Department of Molecular Medicine and Surgery, Karolinska Institutet.
Research
We investigate new pathogenic mechanisms of diabetes complications. The main focus of our research is how diabetes affects hypoxia, Notch and other signaling pathways and how this contributes to the development of diabetes complications including diabetic nephropathy, diabetic foot ulcer, infection and diabetic heart disease. We use clinical samples together with animal and cellular models of diabetes as well as genetically-modified mice to conduct mechanistical, translational, and clinical research.
Articles
- Article: BRITISH JOURNAL OF PHARMACOLOGY. 2025;182(2):417-431Collado A; Jiao T; Kontidou E; Carvalho LRRA; Chernogubova E; Yang J; Zaccagnini G; Zhao A; Tengbom J; Zheng X; Rethi B; Alvarsson M; Catrina S-B; Mahdi A; Carlstroem M; Martelli F; Pernow J; Zhou Z
- Article: EMBO REPORTS. 2024;25(4):1752-1772Zhao A; Jiang H; Palomares AR; Larsson A; He W; Grunler J; Zheng X; Wallberg KAR; Catrina S-B; Deng Q
- Article: EMBO MOLECULAR MEDICINE. 2024;16(3):596-615Wang S; Nikamo P; Laasonen L; Gudbjornsson B; Ejstrup L; Iversen L; Lindqvist U; Alm JJ; Eisfeldt J; Zheng X; Catrina S-B; Taylan F; Vaz R; Stahle M; Tapia-Paez I
- Article: ANTIOXIDANTS. 2023;12(12):2043Kjellberg A; Lindholm ME; Zheng X; Liwenborg L; Rodriguez-Wallberg KA; Catrina S-B; Lindholm P
- Article: JOURNAL OF CLINICAL INVESTIGATION. 2023;133(17):e167693Yang J; Sundqvist ML; Zheng X; Jiao T; Collado A; Tratsiakovich Y; Mahdi A; Tengbom J; Mergia E; Catrina S-B; Zhou Z; Carlstroem M; Akaike T; Cortese-Krott MM; Weitzberg E; Lundberg JO; Pernow J
- Article: JOURNAL OF AUTOIMMUNITY. 2022;133:102903Sakuraba K; Krishnamurthy A; Sun J; Zheng X; Xu C; Peng B; Engstrom M; Jakobsson P-J; Wermeling F; Catrina S; Gronwall C; Catrina AI; Rethi B
- Article: BMJ OPEN. 2022;12(11):e061870Kjellberg A; Abdel-Halim L; Hassler A; El Gharbi S; Al-Ezerjawi S; Bostrom E; Sundberg CJ; Pernow J; Medson K; Kowalski JH; Rodriguez-Wallberg KA; Zheng X; Catrina S; Runold M; Stahlberg M; Bruchfeld J; Nygren-Bonnier M; Lindholm P
- Article: MBIO. 2022;13(5):e0108622-e01022Teran G; Li H; Catrina S-B; Liu R; Brighenti S; Zheng X; Grunler J; Nylen S; Carow B; Rottenberg ME
- Article: ELIFE. 2022;11:e70714Zheng X; Narayanan S; Xu C; Eliasson Angelstig S; Grunler J; Zhao A; Di Toro A; Bernardi L; Mazzone M; Carmeliet P; Del Sole M; Solaini G; Forsberg EA; Zhang A; Brismar K; Schiffer TA; Rajamand Ekberg N; Botusan IR; Palm F; Catrina S-B
- Article: DIABETES. 2022;71(2):285-297Zhou Z; Collado A; Sun C; Tratsiakovich Y; Mahdi A; Winter H; Chernogubova E; Seime T; Narayanan S; Jiao T; Jin H; Alvarsson M; Zheng X; Yang J; Hedin U; Catrina S-B; Maegdefessel L; Pernow J
- Article: BMJ OPEN. 2021;11(7):e046738Kjellberg A; Douglas J; Pawlik MT; Kraus M; Oscarsson N; Zheng X; Bergman P; Franberg O; Kowalski JH; Nyren SP; Silvanius M; Skold M; Catrina S-B; Rodriguez-Wallberg KA; Lindholm P
- Article: ANTIOXIDANTS. 2021;10(7):1070Dallner G; Bentinger M; Hussain S; Sinha I; Yang J; Schwank-Xu C; Zheng X; Swiezewska E; Brismar K; Valladolid-Acebes I; Tekle M
- Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2021;141(3):659-671miR-19a/b and miR-20a Promote Wound Healing by Regulating the Inflammatory Response of KeratinocytesLi D; Peng H; Qu L; Sommar P; Wang A; Chu T; Li X; Bi X; Liu Q; Serezal IG; Rollman O; Lohcharoenkal W; Zheng X; Angelstig SE; Grunler J; Pivarcsi A; Sonkoly E; Catrina S-B; Xiao C; Stahle M; Mi Q-S; Zhou L; Landen NX
- Article: COMMUNICATIONS BIOLOGY. 2020;3(1):768Narayanan S; Angelstig SE; Xu C; Grunler J; Zhao A; Zhu W; Landen NX; Stahle M; Zhang J; Ivan M; Maltesen RG; Botusan IR; Ekberg NR; Zheng X; Catrina S-B
- Article: EBIOMEDICINE. 2019;44:489-501Petrus P; Fernandez TL; Kwon MM; Huang JL; Lei V; Safikhan NS; Karunakaran S; O'Shannessy DJ; Zheng X; Catrina S-B; Albone E; Laine J; Virtanen K; Clee SM; Kieffer TJ; Noll C; Carpentier AC; Johnson JD; Ryden M; Conway EM
- Article: JOURNAL OF DIABETES RESEARCH. 2019;2019:2936962-8Ekberg NR; Eliasson S; Li YW; Zheng X; Chatzidionysiou K; Falhammar H; Gu HF; Catrina S-B
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2019;116(14):6985-6994Zheng X; Narayanan S; Sunkari VG; Eliasson S; Botusan IR; Grunler J; Catrina AI; Radtke F; Xu C; Zhao A; Ekberg NR; Lendahl U; Catrina S-B
- Article: JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. 2018;(138)Zheng X; Ho CQW; Zheng X; Lee KL; Gradin K; Pereira TS; Berggren P-O; Ali Y
- Article: JACC-BASIC TO TRANSLATIONAL SCIENCE. 2018;3(4):450-463Yang J; Zheng X; Mahdi A; Zhou Z; Tratsiakovich Y; Jiao T; Kiss A; Kovamees O; Alvarsson M; Catrina S-B; Lundberg JO; Brismar K; Pernow J
- Article: PLOS ONE. 2018;13(3):e0193084Botusan IR; Zheng X; Narayanan S; Grunler J; Sunkari VG; Calissendorff FS; Ansurudeen I; Illies C; Svensson J; Jansson J-O; Ohlsson C; Brismar K; Catrina S-B
- Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2017;137(12):2630-2638Li X; Li D; Wang A; Chu T; Lohcharoenkal W; Zheng X; Grunler J; Narayanan S; Eliasson S; Herter EK; Wang Y; Ma Y; Ehrstrom M; Eidsmo L; Kasper M; Pivarcsi A; Sonkoly E; Catrina S-B; Stahle M; Landen NX
- Article: EXPERIMENTAL CELL RESEARCH. 2017;358(2):129-139Zheng X; Narayanan S; Zheng X; Luecke-Johansson S; Gradin K; Catrina S-B; Poellinger L; Pereira TS
- Article: ACTA PHYSIOLOGICA. 2014;210(3):590-599Yang J; Zheng X; Haugen F; Dare E; Lovdahl C; Schulte G; Fredholm BB; Valen G
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2014;111(7):2560-2565Zheng X; Zhou A-X; Rouhi P; Uramoto H; Boren J; Cao Y; Pereira T; Akyurek LM; Poellinger L
- Article: DIABETES CARE. 2013;36(2):415-421Gu HF; Zheng X; Abu Seman N; Gu T; Botusan IR; Sunkari VG; Lokman EF; Brismar K; Catrina S-B
- Article: CELL DEATH & DISEASE. 2012;3(6):e322Zheng X; Zheng X; Wang X; Ma Z; Sunkari VG; Botusan I; Takeda T; Bjorklund A; Inoue M; Catrina S-B; Brismar K; Poellinger L; Pereira TS
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2008;105(9):3368-3373Zheng X; Linke S; Dias JM; Zheng X; Gradin K; Wallis TP; Hamilton BR; Gustafsson M; Ruas JL; Wilkins S; Bilton RL; Brismar K; Whitelaw ML; Pereira T; Gorman JJ; Ericson J; Peet DJ; Lendahl U; Poellinger L
- Article: CELL CYCLE. 2006;5(23):2720-2722Pereira T; Zheng X; Poellinger L
- Article: MOLECULAR AND CELLULAR BIOLOGY. 2006;26(12):4628-4641Zheng X; Ruas JL; Cao R; Salomons FA; Cao Y; Poellinger L; Pereira T
- Article: DEVELOPMENTAL CELL. 2005;9(5):617-628Gustafsson MV; Zheng XW; Pereira T; Gradin K; Jin SB; Lundkvist J; Ruas JL; Poellinger L; Lendahl U; Bondesson M
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2003;278(9):6816-6823Pereira T; Zheng XW; Ruas JL; Tanimoto K; Poellinger L
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All other publications
- Corrigendum: JOURNAL OF DIABETES RESEARCH. 2021;2021:9827150-1Ekberg NR; Eliasson S; Li YW; Zheng X; Chatzidionysiou K; Falhammar H; Gu HF; Catrina S-B
- Review: DIABETOLOGIA. 2021;64(4):709-716Catrina S-B; Zheng X
- Letter: CLINICAL AND TRANSLATIONAL MEDICINE. 2021;11(1):e273Ye Y; Chen Y; Sun J; Zhang H; Li W; Wang W; Zheng X; Catrina S-B
- Published conference paper: DIABETES-METABOLISM RESEARCH AND REVIEWS. 2016;32:179-185Catrina S-B; Zheng X
- Editorial comment: ENDOCRINE. 2014;46(2):347-350Sunkari VG; Botusan IR; Savu O; Grunler J; Zheng X; Gustafsson J-A; Brismar K; Catrina S-B
Employments
- Senior Research Specialist, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2022-
Degrees and Education
- Docent, Karolinska Institutet, 2025
- Degree Of Doctor Of Philosophy, Department of Cell and Molecular Biology, Karolinska Institutet, 2009