Virpi Töhönen

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: GENOME RESEARCH. 2021;31(11):1983-1993
Embryonic LTR retrotransposons supply promoter modules to somatic tissues
Hashimoto K; Jouhilahti E-M; Tohonen V; Carninci P; Kere J; Katayama S
Article: GENOME MEDICINE. 2021;13(1):40
Integration of whole genome sequencing into a healthcare setting: high diagnostic rates across multiple clinical entities in 3219 rare disease patients
Stranneheim H; Lagerstedt-Robinson K; Magnusson M; Kvarnung M; Nilsson D; Lesko N; Engvall M; Anderlid B-M; Arnell H; Johansson CB; Barbaro M; Bjorck E; Bruhn H; Eisfeldt J; Freyer C; Grigelioniene G; Gustavsson P; Hammarsjo A; Hellstrom-Pigg M; Iwarsson E; Jemt A; Laaksonen M; Enoksson SL; Malmgren H; Naess K; Nordenskjold M; Oscarson M; Pettersson M; Rasi C; Rosenbaum A; Sahlin E; Sardh E; Stodberg T; Tesi B; Tham E; Thonberg H; Tohonen V; von Dobeln U; Vassiliou D; Vonlanthen S; Wikstrom A-C; Wincent J; Winqvist O; Wredenberg A; Ygberg S; Zetterstrom RH; Marits P; Soller MJ; Nordgren A; Wirta V; Lindstrand A; Wedell A
Article: NEUROENDOCRINOLOGY. 2021;111(1-2):27-44
Motor Function Deficits in the Estrogen Receptor Beta Knockout Mouse: Role on Excitatory Neurotransmission and Myelination in the Motor Cortex
Varshney MK; Yu NY-L; Katayama S; Li X; Liu T; Wu W-F; Tohonen V; Krjutskov K; Kere J; Fan X; Inzunza J; Gustafsson J-A; Nalvarte I
Article: HUMAN REPRODUCTION. 2018;33(9):1677-1683
Spermatogonial quantity in human prepubertal testicular tissue collected for fertility preservation prior to potentially sterilizing therapy
Stukenborg J-B; Alves-Lopes JP; Kurek M; Albalushi H; Reda A; Keros V; Tohonen V; Bjarnason R; Romerius P; Sundin M; Nystrom UN; Langenskiold C; Vogt H; Henningsohn L; Mitchell RT; Soder O; Petersen C; Jahnukainen K
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2017;114(19):E3816-E3822
Estrogen receptor β, a regulator of androgen receptor signaling in the mouse ventral prostate
Wu W-F; Maneix L; Insunza J; Nalvarte I; Antonson P; Kere J; Yu NY-L; Tohonen V; Katayama S; Einarsdottir E; Krjutskov K; Dai Y-B; Huang B; Su W; Warner M; Gustafsson J-A
Article: DEVELOPMENT. 2016;143(19):3459-3469
The human PRD-like homeobox gene LEUTX has a central role in embryo genome activation
Jouhilahti E-M; Madissoon E; Vesterlund L; Tohonen V; Krjutskov K; Reyes AP; Petropoulos S; Mansson R; Linnarsson S; Burglin T; Lanner F; Hovatta O; Katayama S; Kere J
Article: SCIENTIFIC REPORTS. 2016;6:28995
Characterization and target genes of nine human PRD-like homeobox domain genes expressed exclusively in early embryos
Madissoon E; Jouhilahti E-M; Vesterlund L; Tohonen V; Krjutskov K; Petropoulous S; Einarsdottir E; Linnarssons S; Lanner F; Mansson R; Hovatta O; Burglin TR; Katayama S; Kere J
Article: REPRODUCTION. 2016;151(3):253-259
Estrogen rleceptor β controls MMP-19 expression in mouse ovaries during ovulation
Nalvarte I; Tohonen V; Lindeberg M; Varshney M; Gustafsson J-A; Inzunza J
Article: NATURE COMMUNICATIONS. 2015;6:8207
Novel PRD-like homeodomain transcription factors and retrotransposon elements in early human development
Tohonen V; Katayama S; Vesterlund L; Jouhilahti E-M; Sheikhi M; Madissoon E; Filippini-Cattaneo G; Jaconi M; Johnsson A; Burglin TR; Linnarsson S; Hovatta O; Kere J
Article: STEM CELLS. 2015;33(5):1434-1446
Perturbations of Heart Development and Function in Cardiomyocytes from Human Embryonic Stem Cells with Trisomy 21
Bosman A; Letourneau A; Sartiani L; Del Lungo M; Ronzoni F; Kuziakiv R; Tohonen V; Zucchelli M; Santoni F; Guipponi M; Dumevska B; Hovatta O; Antonarakis SE; Jaconi ME
Article: REPRODUCTION. 2014;147(6):875-883
Mice depleted of the coxsackievirus and adenovirus receptor display normal spermatogenesis and an intact blood-testis barrier
Sultana T; Hou M; Stukenborg J-B; Tohonen V; Inzunza J; Chagin AS; Sollerbrant K
Article: PLOS ONE. 2014;9(8):e102949
Differences in Gene Expression between Mouse and Human for Dynamically Regulated Genes in Early Embryo
Madissoon E; Tohonen V; Vesterlund L; Katayama S; Unneberg P; Inzunza J; Hovatta O; Kere J
Article: BIOINFORMATICS. 2013;29(22):2943-2945
SAMstrt: statistical test for differential expression in single-cell transcriptome with spike-in normalization
Katayama S; Tohonen V; Linnarsson S; Kere J
Article: BIOMED RESEARCH INTERNATIONAL. 2013;2013:489032-8
Does Cryopreservation of Ovarian Tissue Affect the Distribution and Function of Germinal Vesicle Oocytes Mitochondria?
Salehnia M; Tohonen V; Zavareh S; Inzunza J
Article: INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY. 2011;55(3):313-319
Co-localization of neural cell adhesion molecule and fibroblast growth factor receptor 2 in early embryo development
Vesterlund L; Tohonen V; Hovatta O; Kere J
Article: FERTILITY AND STERILITY. 2010;93(8):2621-2626
Selective insulin-like growth factor-I antagonist inhibits mouse embryo development in a dose-dependent manner
Inzunza J; Danielsson O; Lalitkumar PG; Larsson O; Axelson M; Tohonen V; Danielsson KG; Stavreus-Evers A
Article: EVOLUTION AND DEVELOPMENT. 2010;12(3):329-342
Evolution and human tissue expression of the Cres/Testatin subgroup genes, a reproductive tissue specific subgroup of the type 2 cystatins
Frygelius J; Arvestad L; Wedell A; Tohonen V
Article: PLOS ONE. 2010;5(4):e10263
A Teratocarcinoma-Like Human Embryonic Stem Cell (hESC) Line and Four hESC Lines Reveal Potentially Oncogenic Genomic Changes
Hovatta O; Jaconi M; Tohonen V; Bena F; Gimelli S; Bosman A; Holm F; Wyder S; Zdobnov EM; Irion O; Andrews PW; Antonarakis SE; Zucchelli M; Kere J; Feki A
Article: HUMAN MOLECULAR GENETICS. 2009;18(15):2813-2824
PDK1 signaling in oocytes controls reproductive aging and lifespan by manipulating the survival of primordial follicles
Reddy P; Adhikari D; Zheng W; Liang S; Hamalainen T; Tohonen V; Ogawa W; Noda T; Volarevic S; Huhtaniemi I; Liu K
Article: NEW ENGLAND JOURNAL OF MEDICINE. 2009;361(5):489-495
AGC1 Deficiency Associated with Global Cerebral Hypomyelination
Wibom R; Lasorsa FM; Tohonen V; Barbaro M; Sterky FH; Kucinski T; Naess K; Jonsson M; Pierri CL; Palmieri F; Wedell A
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY (EJE). 2008;158(5):729-739
Activating transcription factor 3:: a hormone responsive gene in the etiology of hypospadias
Beleza-Meireles A; Tohonen V; Soderhall C; Schwentner C; Radmayr C; Kockum I; Nordenskjold A
Article: REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY. 2007;5:8
Studies of a co-chaperone of the androgen receptor, FKBP52, as candidate for hypospadias
Beleza-Meireles A; Barbaro M; Wedell A; Tohonen V; Nordenskjold A
Article: SEXUAL DEVELOPMENT. 2007;1(6):363-372
The reproductive tissue specific cystatin subgroup of genes:: Expression during gonadal development in wildtype and testatin knockout animals
Frygelius J; Oscarson M; Nordqvist K; Wedell A; Toehoenen V
Article: MOLECULAR AND CELLULAR BIOLOGY. 2005;25(12):4892-4902
Normal sexual development and fertility in testatin knockout mice
Töhönen V; Frygelius J; Mohammadieh M; Kvist U; Pelliniemi LJ; O'Brien K; Nordqvist K; Wedell A
Article: MOLECULAR HUMAN REPRODUCTION. 2002;8(1):8-15
Isolation of the human testatin gene and analysis in patients with abnormal gonadal development
Eriksson A; Töhönen V; Wedell A; Nordqvist K
Article: CANCER RESEARCH. 2000;60(4):1054-1061
Mage-b4, a novel Melanoma antigen (MAGE) gene specifically expressed during germ cell differentiation
Österlund C; Töhönen V; Forslund K; Nordqvist K
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1998;95(24):14208-14213
Testatin:: A cystatin-related gene expressed during early testis development
Töhönen V; Österlund C; Nordqvist K
Article: INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY. 1997;41(4):627-638
An mRNA differential display strategy for cloning genes expressed during mouse gonad development
Nordqvist K; Tohonen V
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Alla övriga publikationer

Review: ENDOCRINE DEVELOPMENT. 2003;5:1-23
Male sex determination and prenatal differentiation of the testis.
Töhönen V; Ritzén EM; Nordqvist K; Wedell A
Thesis / dissertation: 2002
Novel genes in gonadal development
Töhönen, Virpi

Anställningar

Forskningsspecialist, Molekylär medicin och kirurgi, Karolinska Institutet, 2022-

Examina och utbildning

MEDICINE DOKTORSEXAMEN, Institutionen för cell- och molekylärbiologi, Karolinska Institutet, 2002

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