Urban Ekman

Om mig
Publikationer
Forskningsbidrag
CV
Populärvetenskap och samverkan

Om mig

Docent. Med. Dr. Leg. Psykolog.

Forskningsbeskrivning

Kognitiva nedsättningar kan orsakas av ett brett spektrum av medicinska
tillstånd och medför ofta svåra konsekvenser för den drabbade i form av
minskat oberoende och funktionalitet. Det finns ett stort behov
av effektivare metoder, både gällande tidig diagnostik men även gällande
psykologiska behandlingsmetoder för att öka självständighet och
förbättra välmåendet.
Min forskningsinriktning har två huvudspår:
1. Det första spåret syftar till att skapa en innovativ
forskningsplattform för utveckling och utvärdering av psykologiska
behandlingsmetoder och kognitiva rehabilitering för personer med kognitiv
svikt. Vi kommer att utvärdera både feasibility och effekter av
behandling/rehabilitering. Målet är att förbättra prevention
och psykiskt mående för en patientgrupp som många gånger saknar
verksamma stödinsatser.
2. Det andra spåret är att vidareutveckla och utvärdera det pågående
MemClin-projektet (se webbadress nedan). MemClin-projektets storskalighet
och populationsbaserade karaktär gör det till en viktig plattform för
klinisk relevant forskning under många år framöver. I nuläget består
databasen av kliniska data från ungefär 3000 personer, med en förväntad
tillströmning av cirka 1000 nya individer per år. Projektet är inriktat
på att öka kunskapen om tidiga kliniska manifestationer av olika
neurodegenerativa sjukdomar och andra kognitiv tillstånd. Etableringen av
MemClin gör det möjligt att bygga robusta modeller för att förbättra
den diagnostiska precisionen och stärka den longitudinella prediktionen.

Artiklar

Article: BRAIN COMMUNICATIONS. 2024;6(5):fcae290
Cerebrovascular and Alzheimer's disease biomarkers in dementia with Lewy bodies and other dementias
Rennie A; Ekman U; Shams S; Ryden L; Samuelsson J; Zettergren A; Kern S; Oppedal K; Blanc F; Hort J; Garcia-Ptacek S; Antonini A; Lemstra AW; Padovani A; Kramberger MG; Rektorova I; Walker Z; Snaedal J; Pardini M; Taylor J-P; Bonanni L; Granberg T; Aarsland D; Skoog I; Wahlund L-O; Kivipelto M; Westman E; Ferreira D
Article: CLINICAL NEUROPSYCHOLOGIST. 2024;:1-15
Methods for assessment of rey auditory verbal learning test performance in memory clinic patients and healthy adults - at the cross-roads of learning theory and clinical utility
Almkvist O; Rennie A; Westman E; Wallert J; Ekman U
Article: SCIENTIFIC REPORTS. 2024;14(1):9513
Investigating underlying brain structures and influence of mild and subjective cognitive impairment on dual-task performance in people with Parkinson's disease
Albrecht F; Johansson H; Ekman U; Poulakis K; Bezuidenhout L; Pereira JB; Franzen E
Article: JOURNAL OF ORAL REHABILITATION. 2023;50(12):1422-1431
White matter abnormalities mediate the association between masticatory dysfunction and cognition among older adults
Hedberg L; Kumar A; Skott P; Smedberg J-I; Seiger A; Sandborgh-Englund G; Nordin LE; Kareholt I; Tzortzakakis A; Westman E; Trulsson M; Ekman U
Article: NEUROBIOLOGY OF AGING. 2023;129:41-49
Comparing three neuropsychological subgrouping approaches in subjective and mild cognitive impairment from a naturalistic multicenter study
Rennie A; Ekman U; Wallert J; Muehlboeck J-S; Eriksdotter M; Wahlund L-O; Ferreira D; Westman E
Article: PHYSICAL THERAPY. 2023;103(8):pzad065
Struggling to Keep Up and Have a Good Life: A Qualitative Study of Living With Impaired Balance Control Due to Multiple Sclerosis
Wallin A; Franzen E; Ekman U; Johansson S
Article: BRAIN AND BEHAVIOR. 2023;13(4):e2948
Using functional near-infrared spectroscopy to measure prefrontal cortex activity during dual-task walking and navigated walking: A feasibility study
Kvist A; Bezuidenhout L; Johansson H; Albrecht F; Ekman U; Conradsson DM; Franzen E
Article: JOURNAL OF ALZHEIMER'S DISEASE. 2023;92(2):605-614
The Association Between Temporal Atrophy and Episodic Memory Is Moderated by Education in a Multi-Center Memory Clinic Sample
Gyllenhammar M; Rennie A; Padilla DF; Wallert J; Rydstrom A; Wahlund L-O; Eriksdotter M; Westman E; Ekman U
Article: PILOT AND FEASIBILITY STUDIES. 2023;9(1):41
A highly challenging balance training intervention for people with multiple sclerosis: a feasibility trial
Wallin A; Franzen E; Ekman U; Piehl F; Johansson S
Article: MULTIPLE SCLEROSIS AND RELATED DISORDERS. 2022;67:104181
Cognitive-motor interference in people with mild to moderate multiple sclerosis, in comparison with healthy controls
Wallin A; Franz E; Bezuidenhout L; Ekman U; Piehl F; Johansson S
Article: PARKINSONISM AND RELATED DISORDERS. 2022;102:19-29
Unraveling Parkinson's disease heterogeneity using subtypes based on multimodal data
Albrecht F; Poulakis K; Freidle M; Johansson H; Ekman U; Volpe G; Westman E; Pereira JB; Franz E
Article: NPJ PARKINSON'S DISEASE. 2022;8(1):12
Behavioural and neuroplastic effects of a double-blind randomised controlled balance exercise trial in people with Parkinson's disease
Freidle M; Johansson H; Ekman U; Lebedev AV; Schalling E; Thompson WH; Svenningsson P; Lovden M; Abney A; Albrecht F; Steurer H; Leavy B; Holmin S; Hagstromer M; Franzen E
Article: JOURNAL OF PARKINSON’S DISEASE. 2021;11(4):2057-2071
Effects of a Highly Challenging Balance Training Program on Motor Function and Brain Structure in Parkinson's Disease
Albrecht F; Pereira JB; Mijalkov M; Freidle M; Johansson H; Ekman U; Westman E; Franzen E
Article: BMC SPORTS SCIENCE, MEDICINE AND REHABILITATION. 2021;13(1):70
ReCOV: recovery and rehabilitation during and after COVID-19-a study protocol of a longitudinal observational study on patients, next of kin and health care staff
Rydwik E; Anmyr L; Regardt M; McAllister A; Zarenoe R; Akerman E; Orrevall Y; Bragesjo M; Dahl O; Kemani MK; Nordstrand L; Ekman U; Holmstrom L; Nygren-Bonnier M
Article: BMC ORAL HEALTH. 2021;21(1):297
Cognitive changes and neural correlates after oral rehabilitation procedures in older adults: a protocol for an interventional study
Hedberg L; Ekman U; Nordin LE; Smedberg J-I; Skott P; Seiger A; Sandborgh-Englund G; Westman E; Kumar A; Trulsson M
Article: AGING. 2021;13(10):13430-13442
Cognitive dedifferentiation as a function of cognitive impairment in the ADNI and MemClin cohorts
Wallert J; Rennie A; Ferreira D; Muehlboeck J-S; Wahlund L-O; Westman E; Ekman U
Article: NEUROREHABILITATION AND NEURAL REPAIR. 2021;35(4):356-366
Dual-Task Effects During a Motor-Cognitive Task in Parkinson's Disease: Patterns of Prioritization and the Influence of Cognitive Status
Johansson H; Ekman U; Rennie L; Peterson DS; Leavy B; Franzen E
Article: PLOS ONE. 2021;16(5):e0251849
Measuring implicit sequence learning and dual task ability in mild to moderate Parkinson′s disease: A feasibility study
Freidle M; Johansson H; Lebedev AV; Ekman U; Lovden M; Franzen E
Journal article: ALZHEIMER'S AND DEMENTIA. 2020;16(S4)
Subtypes of Alzheimer’s disease and the ATN biomarker scheme
Cedres N; Ekman U; Ferreira D; Westman E
Article: PARKINSON'S DISEASE. 2020;2020:2410863-12
Feasibility Aspects of Exploring Exercise-Induced Neuroplasticity in Parkinson's Disease: A Pilot Randomized Controlled Trial
Johansson H; Freidle M; Ekman U; Schalling E; Leavy B; Svenningsson P; Hagstromer M; Franzen E
Article: BMC GERIATRICS. 2020;20(1):93
The MemClin project: a prospective multi memory clinics study targeting early stages of cognitive impairment
Ekman U; Ferreira D; Muehlboeck J-S; Wallert J; Rennie A; Eriksdotter M; Wahlund L-O; Westman E
Article: NEURODEGENERATIVE DISEASES. 2020;20(4):153-164
Brain Atrophy Subtypes and the ATN Classification Scheme in Alzheimer's Disease
Cedres N; Ekman U; Poulakis K; Shams S; Cavallin L; Muehlboeck S; Granberg T; Wahlund L-O; Ferreira D; Westman E
Article: FRONTIERS IN PSYCHOLOGY. 2020;11:600841
Evaluation of a Novel Psychological Intervention Tailored for Patients With Early Cognitive Impairment (PIPCI): Study Protocol of a Randomized Controlled Trial
Ekman U; Kemani MK; Wallert J; Wicksell RK; Holmstrom L; Ngandu T; Rennie A; Akenine U; Westman E; Kivipelto M
Article: BMC NEUROLOGY. 2019;19(1):280
The EXPANd trial: effects of exercise and exploring neuroplastic changes in people with Parkinson's disease: a study protocol for a double-blinded randomized controlled trial
Franzen E; Johansson H; Freidle M; Ekman U; Wallen MB; Schalling E; Lebedev A; Lovden M; Holmin S; Svenningsson P; Hagstromer M
Article: JOURNAL OF HEAD TRAUMA REHABILITATION. 2019;34(3):189-198
Pharmaco-fMRI in Patients With Traumatic Brain Injury: A Randomized Controlled Trial With the Monoaminergic Stabilizer (-)-OSU6162
Berginstrom N; Nordstrom P; Ekman U; Eriksson J; Nyberg L; Nordstrom A
Article: ACTA NEUROLOGICA SCANDINAVICA. 2019;139(3):254-259
Rehabilitation in chronic spatial neglect strengthens resting-state connectivity
Wahlin A; Fordell H; Ekman U; Lenfeldt N; Malm J
Journal article: ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION. 2018;99(10):e10
Rehabilitation in Chronic Neglect Strengthens Functional Connectivity Between Nodes of the Dorsal Attention Network
Fordell H; Wåhlin A; Ekman U; Malm J; Lenfeldt N
Article: ACTA NEUROLOGICA SCANDINAVICA. 2018;138(4):284-292
Increase of frontal neuronal activity in chronic neglect after training in virtual reality
Ekman U; Fordell H; Eriksson J; Lenfeldt N; Wahlin A; Eklund A; Malm J
Article: JOURNAL OF HEAD TRAUMA REHABILITATION. 2018;33(4):266-274
Using Functional Magnetic Resonance Imaging to Detect Chronic Fatigue in Patients With Previous Traumatic Brain Injury: Changes Linked to Altered Striato-Thalamic-Cortical Functioning
Berginstrom N; Nordstroem P; Ekman U; Eriksson J; Andersson M; Nyberg L; Nordstrom A
Article: SCIENTIFIC REPORTS. 2018;8(1):8431
The A/T/N biomarker scheme and patterns of brain atrophy assessed in mild cognitive impairment
Ekman U; Ferreira D; Westman E
Article: FRONTIERS IN AGING NEUROSCIENCE. 2018;10:144
Differentiating Patients at the Memory Clinic With Simple Reaction Time Variables: A Predictive Modeling Approach Using Support Vector Machines and Bayesian Optimization
Wallert J; Westman E; Ulinder J; Annerstedt M; Terzis B; Ekman U
Article: INTELLIGENCE. 2017;64:9-17
The worst performance rule with elderly in abnormal cognitive decline
Wallert J; Ekman U; Westman E; Madison G
Article: SCIENTIFIC REPORTS. 2017;7:46263
Distinct subtypes of Alzheimer's disease based on patterns of brain atrophy: longitudinal trajectories and clinical applications
Ferreira D; Verhagen C; Andres Hernandez-Cabrera J; Cavallin L; Guo C-J; Ekman U; Muehlboeck J-S; Simmons A; Barroso J; Wahlund L-O; Westman E
Article: ACTA NEUROLOGICA SCANDINAVICA. 2015;132(2):79-88
Cognitive function in the early phase of Parkinson's disease, a five-year follow-up
Domellof ME; Ekman U; Forsgren L; Elgh E
Article: FRONTIERS IN NEUROSCIENCE. 2014;8:207
Longitudinal changes in task-evoked brain responses in Parkinson's disease patients with and without mild cognitive impairment
Ekman U; Eriksson J; Forsgren L; Domellof ME; Elgh E; Lundquist A; Nyberg L
Article: LANCET NEUROLOGY. 2012;11(8):679-687
Functional brain activity and presynaptic dopamine uptake in patients with Parkinson's disease and mild cognitive impairment: a cross-sectional study
Ekman U; Eriksson J; Forsgren L; Mo SJ; Riklund K; Nyberg L
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Alla övriga publikationer

Preprint: RESEARCH SQUARE. 2020
Atrophy subtypes and the ATN classification scheme in Alzheimer’s disease
Cedres N; Ekman U; Poulakis K; Shams S; Cavallin L; muehlboeck S; Granberg T; Wahlund L-O; Ferreira D; Westman E
Conference publication: INTERNATIONAL JOURNAL OF STROKE. 2018;13:42
Rehabilitation of chronic spatial neglect strengthens functional connectivity between nodes of the dorsal attention network
Fordell H; Wahlin A; Ekman U; Lenfeldt N; Malm J
Conference publication: INTERNATIONAL JOURNAL OF STROKE. 2018;13:50
REHABILITATION IN CHRONIC NEGLECT USING VR STRENGTHENS CONNECTIVITY BETWEEN NODES OF THE DORSAL ATTENTION NETWORK
Fordell H; Wahlin A; Ekman U; Lenfeldt N; Malm J
Conference publication: BRAIN INJURY. 2017;31(6-7):755
Fatigue after traumatic brain injury is linked to altered striato-thalamic-cortical functioning
Berginstrom N; Nordstrom P; Ekman U; Eriksson J; Andersson M; Nyberg L; Nordstrom A
Conference publication: JOURNAL OF PSYCHOPHYSIOLOGY. 2013;27:69-70
Working Memory Updating Training in Older Adults: Is Level of Performance After Training Related to Transfer?
Neely AS; Sehlstedt I; Ekman U; Eriksson J; Sandberg P; Qwillbard T; Nyberg L

Forskningsbidrag

Utvärdering av en ny psykologisk behandling med syfte att förbättra den psykologiska hälsan för personer med kognitiv svikt
ALF (Region Stockholm)
1 January 2024 - 31 December 2026
Park-MOVE: Moving towards personalized rehabilitation for Parkinson’s disease informed by diversity, exercise responders and brain activity during motion.
Swedish Research Council
1 January 2023 - 31 December 2026
A collected clinical approach aiming at improved diagnostic accuracy and development of novel effective psychosocial interventions in patients with early-phase cognitive impairments
Centrum för innovativ medicin (CIMED)
1 January 2022 - 31 December 2024
ReCov - Recovery and rehabilitation after Covid-19
Swedish Research Council
1 December 2021 - 30 November 2024
Utveckling och utvärdering av ny förebyggande kognitiva rehabilitering och psykologisk behandling av kognitiv svikt
Familjen Kamprads stiftelse
1 September 2021 - 30 November 2025
Clinical complexity at the memory clinics – is it possible to identify prodromal dementia with only clinical parameters?
Swedish Research Council
1 January 2017 - 31 December 2019
An integrated research project between the Stockholm memory clinics to increase knowledge about prognostic information, cognitive and physiological mechanisms, and diagnostic accuracy
Swedish Research Council for Health Working Life and Welfare
1 January 2016 - 31 December 2017

Anställningar

Anknuten till Forskning, Neurobiologi, vårdvetenskap och samhälle, Karolinska Institutet, 2024-2027
Biträdande Lektor, Neurobiologi, vårdvetenskap och samhälle, Karolinska Institutet, 2020-2024

Examina och utbildning

Docent, Klinisk psykologi, Karolinska Institutet, 2022

Om mig

Forskningsbeskrivning

Artiklar

Alla övriga publikationer

Forskningsbidrag

Anställningar

Examina och utbildning

Nyheter från KI

Kalenderhändelser från KI