Ulf Hedin

Om mig
Publikationer
CV
Populärvetenskap och samverkan

Om mig

Forskargruppsledare för gruppen Kärlkirurgi.

Artiklar

Article: VASCULAR PHARMACOLOGY. 2025;159:107490
PCSK6 ablation in blood circulating cells increases atherosclerotic burden, but improves plaque stability by activating Th17-smooth muscle cell modulatory axis
Suur BE; Karadimou G; Willems CJJM; Bergman O; Lengquist M; Kronqvist M; Baumgartner R; Malin S; Gistera A; Hansson GK; Malarstig A; Hedin U; Ketelhuth DFJ; Matic L
Article: JCI INSIGHT. 2025;10(10):e188281
Mutational landscape of atherosclerotic plaques reveals large clonal cell populations
Steffensen LB; Kavan S; Jensen PS; Pedersen MK; Bottger SM; Larsen MJ; Dembic M; Bergman O; Matic L; Hedin U; Andersen LVB; Lindholt JS; Houlind KC; Riber LP; Thomassen M; Rasmussen LM
Article: JOURNAL OF CARDIOVASCULAR SURGERY. 2025;66(1):17-25
Personalized decision-making for vascular access creation in hemodialysis
Hedin U
Article: EUROPEAN HEART JOURNAL. 2025;46(3):308-322
Atheroma transcriptomics identifies ARNTL as a smooth muscle cell regulator and with clinical and genetic data improves risk stratification
Narayanan S; Vuckovic S; Bergman O; Wirka R; Verdezoto Mosquera J; Chen QS; Baldassarre D; Tremoli E; Veglia F; Lengquist M; Aherrahrou R; Razuvaev A; Gigante B; Bjoerck HM; Miller CL; Quertermous T; Hedin U; Matic L
Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2025;419:132698
Lipoproteins and lipoprotein lipid composition are associated with stages of dysglycemia and subclinical coronary atherosclerosis
Gigante B; Chen Q; Bjorkbacka H; Bjornson E; Brinck J; Chorell E; Djekic D; Edsfeldt A; Engstrom G; Eriksson JW; Gottsater A; Gummesson A; Hagstrom E; Hedin U; Jernberg T; Johnston N; Nilsson L; Nystrom F; Otten J; Rosengren A; Soderberg S; Haglow JT; Ostgren CJ
Article: JVS - VASCULAR SCIENCE. 2025;6:100280
Atherosclerotic plaque instability in symptomatic non-significant carotid stenoses
Cyreus P; Waden K; Hellberg S; Bergman O; Lengquist M; Buckler A; Karlof E; Matic L; Roy J; Marlevi D; Chemaly M; Hedin U
Article: AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 2024;327(6):H1431-H1441
Red blood cells from patients with ST-elevation myocardial infarction and elevated C-reactive protein levels induce endothelial dysfunction
Tengbom J; Humoud R; Kontidou E; Jiao T; Yang J; Hedin U; Zhou Z; Jurga J; Collado A; Mahdi A; Pernow J
Article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2024;39(12):2079-2087
Clinical impact of the Kidney Failure Risk Equation for vascular access planning
Lundstrom UH; Ramspek CL; Dekker FW; van Diepen M; Carrero JJ; Hedin U; Evans M
Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2024;81(1):331
PIEZO1 targeting in macrophages boosts phagocytic activity and foam cell apoptosis in atherosclerosis
Pourteymour S; Fan J; Majhi RK; Guo S; Sun X; Huang Z; Liu Y; Winter H; Baecklund A; Skenteris N-T; Chernogubova E; Werngren O; Li Z; Skogsberg J; Li Y; Matic L; Hedin U; Maegdefessel L; Ehrenborg E; Tian Y; Jin H
Article: ANGIOGENESIS. 2024;27(3):461-474
Human atherosclerotic plaque transcriptomics reveals endothelial beta-2 spectrin as a potential regulator a leaky plaque microvasculature phenotype
Rademakers T; Manca M; Jin H; Orban T; Perisic LM; Frissen HJM; Ruehle F; Hautvast P; van Rijssel J; van Kuijk K; Mees BME; Peutz-Kootstra CJ; Heeneman S; Daemen MJAP; Pasterkamp G; Stoll M; van Zandvoort MAMJ; Hedin U; Dequiedt F; van Buul JD; Sluimer JC; Biessen EAL
Article: ANNALS OF BIOMEDICAL ENGINEERING. 2024;52(4):1347-1358
On the Impact of Residual Strains in the Stress Analysis of Patient-Specific Atherosclerotic Carotid Vessels: Predictions Based on the Homogenous Stress Hypothesis
Mastrofini A; Marino M; Karlof E; Hedin U; Gasser TC
Article: JVS - VASCULAR SCIENCE. 2024;5:100195
Toll-like receptor 4, a potential therapeutic target of lower limb ischemic myopathy that raises further questions
Hakim AH; Hedin U
Article: CARDIOVASCULAR RESEARCH. 2023;119(7):1524-1536
Pyruvate dehydrogenase kinase regulates vascular inflammation in atherosclerosis and increases cardiovascular risk
Forteza MJ; Berg M; Edsfeldt A; Sun J; Baumgartner R; Kareinen I; Casagrande FB; Hedin U; Zhang S; Vuckovic I; Dzeja PP; Polyzos KA; Gistera A; Trauelsen M; Schwartz TW; Dib L; Herrmann J; Monaco C; Matic L; Goncalves I; Ketelhuth DFJ
Article: NATURE CARDIOVASCULAR RESEARCH. 2023;2(7):629-644
The VE-cadherin/AmotL2 mechanosensory pathway suppresses aortic inflammation and the formation of abdominal aortic aneurysms
Zhang Y; Zhang Y; Hutterer E; Hultin S; Bergman O; Kolbeinsdottir S; Jin H; Forteza MJ; Ketelhuth DFJ; Roy J; Hedin U; Enge M; Matic L; Eriksson P; Holmgren L
Article: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2023;65(6):778-786
Long Term Mortality Rate in Patients Treated with Carotid Endarterectomy
Waden K; Hultgren R; Kotopouli MI; Gillgren P; Roy J; Hedin U; Matic L
Article: BIOMOLECULES. 2023;13(6):882
Biliverdin Reductase B Is a Plasma Biomarker for Intraplaque Hemorrhage and a Predictor of Ischemic Stroke in Patients with Symptomatic Carotid Atherosclerosis
Chemaly M; Marlevi D; Iglesias M-J; Lengquist M; Kronqvist M; Bos D; van Dam-Nolen DHK; van der Kolk A; Hendrikse J; Kassem M; Matic L; Odeberg J; de Vries MR; Kooi ME; Hedin U
Article: CIRCULATION RESEARCH. 2023;132(9):1144-1161
FHL5 Controls Vascular Disease-Associated Gene Programs in Smooth Muscle Cells
Wong D; Auguste G; Lino Cardenas CL; Turner AW; Chen Y; Song Y; Ma L; Perry RN; Aherrahrou R; Kuppusamy M; Yang C; Mosquera JV; Dube CJ; Khan MD; Palmore M; Kalra J; Kavousi M; Peyser PA; Matic L; Hedin U; Manichaikul A; Sonkusare SK; Civelek M; Kovacic JC; Bjorkegren JLM; Malhotra R; Miller CL
Article: ATHEROSCLEROSIS. 2023;371:41-53
Interleukin-6 trans-signaling induced laminin switch contributes to reduced trans-endothelial migration of granulocytic cells
Zegeye MM; Matic L; Lengquist M; Hayderi A; Grenegard M; Hedin U; Sirsjo A; Ljungberg LU; Kumawat AK
Article: JVS - VASCULAR SCIENCE. 2023;4:100118
Validating human and mouse tissues commonly used in atherosclerosis research with coronary and aortic reference tissue: similarities but profound differences in disease initiation and plaque stability
van Dijk RA; Kleemann R; Schaapherder AF; van den Bogaerdt A; Hedin U; Matic L; Lindeman JHN
Article: COMPUTERS IN BIOLOGY AND MEDICINE. 2023;152:106364
In silico model of atherosclerosis with individual patient calibration to enable precision medicine for cardiovascular disease
Buckler AJ; Marlevi D; Skenteris NT; Lengquist M; Kronqvist M; Matic L; Hedin U
Article: CELLS. 2022;11(20):3279
Biomechanical Assessment of Macro-Calcification in Human Carotid Atherosclerosis and Its Impact on Smooth Muscle Cell Phenotype
Seime T; van Wanrooij M; Karlof E; Kronqvist M; Johansson S; Matic L; Gasser TC; Hedin U
Article: JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS. 2022;134:105403
Patient-specific biomechanical analysis of atherosclerotic plaques enabled by histologically validated tissue characterization from computed tomography angiography: A case study
Buckler AJ; van Wanrooij M; Andersson M; Karlof E; Matic LP; Hedin U; Gasser TC
Article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2022;37(9):1742-1750
Surgical versus endovascular intervention for vascular access thrombosis: a nationwide observational cohort study
Lundstrom UH; Welander G; Carrero JJ; Hedin U; Evans M
Article: ISCIENCE. 2022;25(5):104219
Clinical risk scores for stroke correlate with molecular signatures of vulnerability in symptomatic carotid patients
Waden K; Karlof E; Narayanan S; Lengquist M; Hansson GK; Hedin U; Roy J; Matic L
Article: ATHEROSCLEROSIS. 2022;348:8-15
A novel anti-inflammatory role links the CARS2 locus to protection from coronary artery disease
Dang A-T; Turner AW; Lau P; Mohottalage D; Fong YKS; Eriksson P; Folkersen L; Matic L; Hedin U; Soubeyrand S; McPherson R
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2022;42(5):659-676
Plaque Evaluation by Ultrasound and Transcriptomics Reveals BCLAF1 as a Regulator of Smooth Muscle Cell Lipid Transdifferentiation in Atherosclerosis
Rykaczewska U; Zhao Q; Saliba-Gustafsson P; Lengquist M; Kronqvist M; Bergman O; Huang Z; Lund K; Waden K; Pons Vila Z; Caidahl K; Skogsberg J; Vukojevic V; Lindeman JHN; Roy J; Hansson GK; Treuter E; Leeper NJ; Eriksson P; Ehrenborg E; Razuvaev A; Hedin U; Matic L
Article: CARDIOVASCULAR RESEARCH. 2022;118(5):1232-1246
Deficiency of myeloid PHD proteins aggravates atherogenesis via macrophage apoptosis and paracrine fibrotic signalling
van Kuijk K; Demandt JAF; Perales-Paton J; Theelen TL; Kuppe C; Marsch E; de Bruijn J; Jin H; Gijbels MJ; Matic L; Mees BME; Reutelingsperger CPM; Hedin U; Biessen EAL; Carmeliet P; Baker AH; Kramann RK; Schurgers LJ; Saez-Rodriguez J; Sluimer JC
Article: DIABETES. 2022;71(2):285-297
Downregulation of Erythrocyte miR-210 Induces Endothelial Dysfunction in Type 2 Diabetes
Zhou Z; Collado A; Sun C; Tratsiakovich Y; Mahdi A; Winter H; Chernogubova E; Seime T; Narayanan S; Jiao T; Jin H; Alvarsson M; Zheng X; Yang J; Hedin U; Catrina S-B; Maegdefessel L; Pernow J
Article: FRONTIERS IN PHARMACOLOGY. 2022;13:988561
Therapeutic potential of the Proprotein Convertase Subtilisin/Kexin family in vascular disease
Suur BE; Chemaly M; Liljeqvist ML; Djordjevic D; Stenemo M; Bergman O; Karlof E; Lengquist M; Odeberg J; Hurt-Camejo E; Eriksson P; Ketelhuth DFJ; Roy J; Hedin U; Nyberg M; Matic L
Article: CARDIOVASCULAR RESEARCH. 2021;117(14):2767-2780
Chitinase 3 like 1 is a regulator of smooth muscle cell physiology and atherosclerotic lesion stability
Tsantilas P; Lao S; Wu Z; Eberhard A; Winski G; Vaerst M; Nanda V; Wang Y; Kojima Y; Ye J; Flores A; Jarr K-U; Pelisek J; Eckstein H-H; Matic L; Hedin U; Tsao PS; Paloschi V; Maegdefessel L; Leeper NJ
Article: CIRCULATION. 2021;144(19):1567-1583
Long Noncoding RNA MIAT Controls Advanced Atherosclerotic Lesion Formation and Plaque Destabilization
Fasolo F; Jin H; Winski G; Chernogubova E; Pauli J; Winter H; Li DY; Glukha N; Bauer S; Metschl S; Wu Z; Koschinsky ML; Reilly M; Pelisek J; Kempf W; Eckstein H-H; Soehnlein O; Matic L; Hedin U; Baecklund A; Bergmark C; Paloschi V; Maegdefessel L
Article: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2021;62(5):716-726
Carotid Plaque Phenotyping by Correlating Plaque Morphology from Computed Tomography Angiography with Transcriptional Profiling
Karlof E; Buckler A; Liljeqvist ML; Lengquist M; Kronqvist M; Toonsi MA; Maegdefessel L; Matic LP; Hedin U
Article: CLINICAL AND TRANSLATIONAL MEDICINE. 2021;11(6):e458
Integrative multiomics analysis of human atherosclerosis reveals a serum response factor-driven network associated with intraplaque hemorrhage
Jin H; Goossens P; Juhasz P; Eijgelaar W; Manca M; Karel JMH; Smirnov E; Sikkink CJJM; Mees BME; Waring O; van Kuijk K; Fazzi GE; Gijbels MJJ; Kutmon M; Evelo CTA; Hedin U; Daemen MJAP; Sluimer JC; Matic L; Biessen EAL
Article: CELLS. 2021;10(6):1276
Proteoglycan 4 Modulates Osteogenic Smooth Muscle Cell Differentiation during Vascular Remodeling and Intimal Calcification
Seime T; Akbulut AC; Liljeqvist ML; Siika A; Jin H; Winski G; van Gorp RH; Karlof E; Lengquist M; Buckler AJ; Kronqvist M; Waring OJ; Lindeman JHN; Biessen EAL; Maegdefessel L; Razuvaev A; Schurgers LJ; Hedin U; Matic L
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2021;41(5):1738-1750
Virtual Transcriptomics Noninvasive Phenotyping of Atherosclerosis by Decoding Plaque Biology From Computed Tomography Angiography Imaging
Buckler AJ; Karlof E; Lengquist M; Gasser TC; Maegdefessel L; Perisic Matic L; Hedin U
Article: VASCULAR MEDICINE. 2021;26(1):3-10
Expression of Interleukin 6 signaling receptors in carotid atherosclerosis
Ziegler L; Lundqvist J; Dreij K; Wallen H; de Faire U; Paulsson-Berne G; Hedin U; Matic L; Gigante B
Article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2021;36(2):275-280
Arteriovenous access placement and renal function decline
Lundstrom UH; Hedin U; Gasparini A; Caskey FJ; Carrero J-J; Evans M
Article: CIRCULATION. 2021;143(2):163-177
RIPK1 Expression Associates With Inflammation in Early Atherosclerosis in Humans and Can Be Therapeutically Silenced to Reduce NF-κB Activation and Atherogenesis in Mice
Karunakaran D; Nguyen M-A; Geoffrion M; Vreeken D; Lister Z; Cheng HS; Otte N; Essebier P; Wyatt H; Kandiah JW; Jung R; Alenghat FJ; Mompeon A; Lee R; Pan C; Gordon E; Rasheed A; Lusis AJ; Liu P; Matic LP; Hedin U; Fish JE; Guo L; Kolodgie F; Virmani R; van Gils JM; Rayner KJ
Journal article: CIRCULATION. 2021;144(19):1567-1583
Long Noncoding RNA MIAT Controls Advanced Atherosclerotic Lesion Formation and Plaque Destabilization
Fasolo F; Jin H; Winski G; Chernogubova E; Pauli J; Winter H; Li DYY; Glukha N; Bauer S; Metschl S; Wu Z; Koschinsky ML; Reilly M; Pelisek J; Kempf W; Eckstein H-H; Soehnlein O; Matic L; Hedin U; Backlund A; Bergmark C; Paloschi V; Maegdefessel L
Article: JVS - VASCULAR SCIENCE. 2021;2:72-78
Resolving the biological paradox of aneurysm formation in children with tuberous sclerosis complex
Hedin U; Brunnstrom H; Dahlin M; Backman T; de Sa VP; Tran P-K
Article: CEREBROVASCULAR DISEASES. 2021;50(1):108-120
Multinational Survey of Current Practice from Imaging to Treatment of Atherosclerotic Carotid Stenosis
Saba L; Mossa-Basha M; Abbott A; Lanzino G; Wardlaw JM; Hatsukami TS; Micheletti G; Balestrieri A; Hedin U; Moody AR; Wintermark M; DeMarco JK
Article: JOURNAL OF INTERNAL MEDICINE. 2021;289(1):53-68
Evidence that a deviation in the kynurenine pathway aggravates atherosclerotic disease in humans
Baumgartner R; Berg M; Matic L; Polyzos KP; Forteza MJ; Hjorth SA; Schwartz TW; Paulson-Berne G; Hansson GK; Hedin U; Ketelhuth DFJ
Article: ATHEROSCLEROSIS. 2020;314:1-9
A neutralizing antibody against DKK1 does not reduce plaque formation in classical murine models of atherosclerosis: Is the therapeutic potential lost in translation?
Rakipovski G; Rolin B; Barascuk N; Lund HE; Bonde MFB; Djordjevic D; Wulff-Larsen PG; Petersen M; Kirk RK; Hultman K; Manfe V; Blume N; Zahn S; Lengquist M; Maegdefessel L; Hovingh GK; Conde-Knape K; Hedin U; Matic L; Nyberg M
Article: JOURNAL OF INFECTIOUS DISEASES. 2020;222(12):2041-2051
Induction of the Coxsackievirus and Adenovirus Receptor in Macrophages During the Formation of Atherosclerotic Plaques
Nilchian A; Plant E; Parniewska MM; Santiago A; Rossignoli A; Skogsberg J; Hedin U; Matic L; Fuxe J
Article: SCIENTIFIC REPORTS. 2020;10(1):19108
Expression of CARD8 in human atherosclerosis and its regulation of inflammatory proteins in human endothelial cells
Paramel GV; Karadimou G; Eremo AG; Ljungberg LU; Hedin U; Olofsson PS; Folkersen L; Berne GP; Sirsjo A; Fransen K
Article: JOURNAL OF CELLULAR PHYSIOLOGY. 2020;235(10):7370-7382
Antagonistic relationship between the unfolded protein response and myocardin-driven transcription in smooth muscle
Zhu B; Daoud F; Zeng S; Matic L; Hedin U; Uvelius B; Rippe C; Albinsson S; Sward K
Article: CIRCULATION RESEARCH. 2020;127(7):911-927
Reactive Oxygen-Forming Nox5 Links Vascular Smooth Muscle Cell Phenotypic Switching and Extracellular Vesicle-Mediated Vascular Calcification
Furmanik M; Chatrou M; van Gorp R; Akbulut A; Willems B; Schmidt H; van Eys G; Bochaton-Piallat M-L; Proudfoot D; Biessen E; Hedin U; Perisic L; Mees B; Shanahan C; Reutelingsperger C; Schurgers L
Article: INTERNATIONAL JOURNAL OF NANOMEDICINE. 2020;15:6137-6152
ORIGINAL RESEARCH Molecular Imaging of Inflammation in a Mouse Model of Atherosclerosis Using a Zirconium-89-Labeled Probe
Ahmed M; Tegnebratt T; Tran TA; Damberg P; Gistera A; Tarnawski L; Bone D; Hedin U; Eriksson P; Holmin S; Gustafsson B; Caidahl K
Article: CELLS. 2020;9(4):E1009-1009
Lack of PCSK6 Increases Flow-Mediated Outward Arterial Remodeling in Mice
Rohl S; Suur BE; Lengquist M; Seime T; Caidahl K; Hedin U; Arner A; Matic L; Razuvaev A
Article: CIRCULATION RESEARCH. 2020;126(5):571-585
PCSK6 Is a Key Protease in the Control of Smooth Muscle Cell Function in Vascular Remodeling
Rykaczewska U; Suur BE; Rohl S; Razuvaev A; Lengquist M; Sabater-Lleal M; van der Laan SW; Miller CL; Wirka RC; Kronqvist M; Diez MG; Vesterlund M; Gillgren P; Odeberg J; Lindeman JH; Veglia F; Humphries SE; de Faire U; Baldassarre D; Tremoli E; Lehtio J; Hansson GK; Paulsson-Berne G; Pasterkamp G; Quertermous T; Hamsten A; Eriksson P; Hedin U; Matic L
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2020;40(2):412-425
MicroRNA-144 Silencing Protects Against Atherosclerosis in Male, but Not Female Mice
Cheng J; Cheng A; Clifford BL; Wu X; Hedin U; Maegdefessel L; Pamir N; Sallam T; Tarling EJ; Vallim TQDA
Article: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 2020;8:619079
Long Non-coding RNA Aerrie Controls DNA Damage Repair via YBX1 to Maintain Endothelial Cell Function
Pham TP; Bink DI; Stanicek L; van Bergen A; van Leeuwen E; Tran Y; Matic L; Hedin U; Wittig I; Dimmeler S; Boon RA
Article: JVS - VASCULAR SCIENCE. 2020;1:13-27
Transcriptomic profiling of experimental arterial injury reveals new mechanisms and temporal dynamics in vascular healing response
Rohl S; Rykaczewska U; Seime T; Suur BE; Diez MG; Gadin JR; Gainullina A; Sergushichev AA; Wirka R; Lengquist M; Kronqvist M; Bergman O; Odeberg J; Lindeman JHN; Quertermous T; Hamsten A; Eriksson P; Hedin U; Razuvaev A; Matic LP
Article: PLOS GENETICS. 2020;16(1):e1008538
Genomic profiling of human vascular cells identifies TWIST1 as a causal gene for common vascular diseases
Nurnberg ST; Guerraty MA; Wirka RC; Rao HS; Pjanic M; Norton S; Serrano F; Perisic L; Elwyn S; Pluta J; Zhao W; Testa S; Park Y; Nguyen T; Ko Y-A; Wang T; Hedin U; Sinha S; Barash Y; Brown CD; Quertermous T; Rader DJ
Article: ATHEROSCLEROSIS. 2020;292:215-223
Endothelin-1 increases expression and activity of arginase 2 via ETB receptors and is co-expressed with arginase 2 in human atherosclerotic plaques
Rafnsson A; Matic LP; Lengquist M; Mahdi A; Shemyakin A; Paulsson-Berne G; Hansson GK; Gabrielsen A; Hedin U; Yang J; Pernow J
Article: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. 2019;317(6):C1128-C1142
Identification of the intermediate filament protein synemin/SYNM as a target of myocardin family coactivators
Sward K; Krawczyk KK; Moren B; Zhu B; Matic L; Holmberg J; Hedin U; Uvelius B; Stenkula K; Rippe C
Article: THROMBOSIS AND HAEMOSTASIS. 2019;119(12):2014-2024
Early Inhibition of P-Selectin/P-Selectin Glycoprotein Ligand-1 Reduces Intimal Hyperplasia in Murine Vein Grafts through Platelet Adhesion
Tseng C-N; Chang Y-T; Yen C-Y; Lengquist M; Kronqvist M; Eriksson EE; Hedin U
Article: ATHEROSCLEROSIS. 2019;288:175-185
Correlation of computed tomography with carotid plaque transcriptomes associates calcification with lesion-stabilization.
Karlöf E; Seime T; Dias N; Lengquist M; Witasp A; Almqvist H; Kronqvist M; Gådin JR; Odeberg J; Maegdefessel L; Stenvinkel P; Matic LP; Hedin U
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2019;116(33):16410-16419
Regulation of CCL2 expression in human vascular endothelial cells by a neighboring divergently transcribed long noncoding RNA
Khyzha N; Khor M; DiStefano PV; Wang L; Matic L; Hedin U; Wilson MD; Maegdefessel L; Fish JE
Article: JOURNAL OF ULTRASOUND IN MEDICINE. 2019;38(7):1723-1731
Noninvasive in vivo Assessment of the Re-endothelialization Process Using Ultrasound Biomicroscopy in the Rat Carotid Artery Balloon Injury Model
Rohl S; Eriksson L; Saxelin R; Lengquist M; Ostenson C-G; Hedin U; Caidahl K; Razuvaev A
Article: JACC-BASIC TO TRANSLATIONAL SCIENCE. 2019;4(3):304-317
Inflammasome-Driven Interleukin-1α and Interleukin-1β Production in Atherosclerotic Plaques Relates to Hyperlipidemia and Plaque Complexity
Jiang X; Wang F; Wang Y; Gistera A; Roy J; Paulsson-Berne G; Hedin U; Lerman A; Hansson GK; Herrmann J; Yan Z-Q
Article: INTERNATIONAL JOURNAL OF NANOMEDICINE. 2019;14:3723-3741
Human serum albumin-based probes for molecular targeting of macrophage scavenger receptors
Ahmed M; Baumgartner R; Aldi S; Dusart P; Hedin U; Gustafsson B; Caidahl K
Article: CIRCULATION. 2019;139(21):2466-2482
Germinal Center-Derived Antibodies Promote Atherosclerosis Plaque Size and Stability
Centa M; Jin H; Hofste L; Hellberg S; Busch A; Baumgartner R; Verzaal NJ; Enoksson SL; Matic LP; Boddul SV; Atzler D; Li DY; Sun C; Hansson GK; Ketelhuth DFJ; Hedin U; Wermeling F; Lutgens E; Binder CJ; Maegdesfessel L; Malin SG
Article: ATHEROSCLEROSIS. 2019;283:127-136
Dual roles of heparanase in human carotid plaque calcification
Aldi S; Eriksson L; Kronqvist M; Lengquist M; Lofling M; Folkersen L; Matic LP; Maegdefessel L; Grinnemo K-H; Li J-P; Osterholm C; Hedin U
Article: CIRCULATION. 2019;139(10):1320-1334
Hematopoietic Deficiency of the Long Noncoding RNA MALAT1 Promotes Atherosclerosis and Plaque Inflammation
Cremer S; Michalik KM; Fischer A; Pfisterer L; Jae N; Winter C; Boon RA; Muhly-Reinholz M; John D; Uchida S; Weber C; Poller W; Guenther S; Braun T; Li DY; Maegdefessel L; Matic LP; Hedin U; Soehnlein O; Zeiher A; Dimmeler S
Article: CELLULAR AND MOLECULAR BIOENGINEERING. 2019;12(1):15-32
Molecular Imaging of a New Multimodal Microbubble for Adhesion Molecule Targeting
Ahmed M; Gustafsson B; Aldi S; Dusart P; Egri G; Butler LM; Bone D; Dahne L; Hedin U; Caidahl K
Article: EUROPEAN HEART JOURNAL. 2019;40(4):372-382
Deficiency of the T cell regulator Casitas B-cell lymphoma-B aggravates atherosclerosis by inducing CD8⁺ T cell-mediated macrophage death
Seijkens TTP; Poels K; Meiler S; van Tiel CM; Kusters PJH; Reiche M; Atzler D; Winkels H; Tjwa M; Poelman H; Slutter B; Kuiper J; Gijbels M; Kuivenhoven JA; Matic LP; Paulsson-Berne G; Hedin U; Hansson GK; Nicolaes GAF; Daemen MJAP; Weber C; Gerdes N; de Winther MPJ; Lutgens E
Article: NATURE METABOLISM. 2019;1(1):98-110
The long noncoding RNA CHROME regulates cholesterol homeostasis in primates
Hennessy EJ; van Solingen C; Scacalossi KR; Ouimet M; Afonso MS; Prins J; Koelwyn GJ; Sharma M; Ramkhelawon B; Carpenter S; Busch A; Chernogubova E; Matic LP; Hedin U; Maegdefessel L; Caffrey BE; Hussein MA; Ricci EP; Temel RE; Garabedian MJ; Berger JS; Vickers KC; Kanke M; Sethupathy P; Teupser D; Holdt LM; Moore KJ
Article: CARDIOVASCULAR RESEARCH. 2019;115(1):230-242
Long non-coding RNA H19 regulates endothelial cell aging via inhibition of STAT3 signalling
Hofmann P; Sommer J; Theodorou K; Kirchhof L; Fischer A; Li Y; Perisic L; Hedin U; Maegdefessel L; Dimmeler S; Boon RA
Article: PLOS ONE. 2019;14(8):e0221477
Oncostatin M reduces atherosclerosis development in APOE*3Leiden.CETP mice and is associated with increased survival probability in humans
van Keulen D; Pouwer MG; Emilsson V; Matic LP; Pieterman EJ; Hedin U; Gudnason V; Jennings LL; Holmstrom K; Nielsen BS; Pasterkamp G; Lindeman JHN; van Gool AJ; Gelpke MDS; Princen HMG; Tempel D
Article: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. 2018;315(6):c873-c884
Expression of endothelin type B receptors (EDNRB) on smooth muscle cells is controlled by MKL2, ternary complex factors, and actin dynamics
Krawczyk KK; Skovsted GF; Perisic L; Dreier R; Berg JO; Hedin U; Rippe C; Sward K
Article: PLOS GENETICS. 2018;14(11):e1007755
Functional regulatory mechanism of smooth muscle cell-restricted LMOD1 coronary artery disease locus
Nanda V; Wang T; Pjanic M; Liu B; Trieu N; Matic LP; Hedin U; Koplev S; Ma L; Franzen O; Ruusalepp A; Schadt EE; Bjorkegren JLM; Montgomery SB; Snyder MP; Quertermous T; Leeper NJ; Miller CL
Article: JOURNAL OF VASCULAR ACCESS. 2018;19(6):535-541
Haemodialysis access thrombosis: Outcomes after surgical thrombectomy versus catheter-directed thrombolytic infusion
Koraen-Smith L; Krasun M; Bottai M; Hedin U; Wahlgren CM; Gillgren P
Article: SCIENTIFIC REPORTS. 2018;8(1):14668
A systems-approach reveals human nestin is an endothelial-enriched, angiogenesis-independent intermediate filament protein
Dusart P; Fagerberg L; Perisic L; Civelek M; Struck E; Hedin U; Uhlen M; Tregouet D-A; Renne T; Odeberg J; Butler LM
Article: MOLECULAR THERAPY METHODS & CLINICAL DEVELOPMENT. 2018;10:17-28
Integrated Human Evaluation of the Lysophosphatidic Acid Pathway as a Novel Therapeutic Target in Atherosclerosis
Aldi S; Matic LP; Hamm G; van Keulen D; Tempel D; Holmstrom K; Szwajda A; Nielsen BS; Emilsson V; Ait-Belkacem R; Lengquist M; Paulsson-Berne G; Eriksson P; Lindeman JHN; Gool AJ; Stauber J; Hedin U; Hurt-Camejo E
Article: CIRCULATION-GENOMIC AND PRECISION MEDICINE. 2018;11(9):e002115
Genetic Susceptibility Loci for Cardiovascular Disease and Their Impact on Atherosclerotic Plaques
van der Laan SW; Siemelink MA; Haitjema S; Asl HF; Perisic L; Mokry M; van Setten J; Malik R; Dichgans M; Worrall BB; Samani NJ; Schunkert H; Erdmann J; Hedin U; Paulsson-Berne G; Bjorkegrenn JLM; de Borst GJ; Asselbergs FW; den Ruijter HM; de Bakker PIW; Pasterkamp G
Article: SCIENTIFIC REPORTS. 2018;8(1):13025
Nexilin/NEXN controls actin polymerization in smooth muscle and is regulated by myocardin family coactivators and YAP
Zhu B; Rippe C; Holmberg J; Zeng S; Perisic L; Albinsson S; Hedin U; Uvelius B; Sward K
Article: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 2018;72(7):769-780
Erythrocytes From Patients With Type 2 Diabetes Induce Endothelial Dysfunction Via Arginase I
Zhou Z; Mahdi A; Tratsiakovich Y; Zahoran S; Kovamees O; Nordin F; Gonzalez AEU; Alvarsson M; Ostenson C-G; Andersson DC; Hedin U; Hermesz E; Lundberg JO; Yang J; Pernow J
Article: JACC-BASIC TO TRANSLATIONAL SCIENCE. 2018;3(4):464-480
Novel Multiomics Profiling of Human Carotid Atherosclerotic Plaques and Plasma Reveals Biliverdin Reductase B as a Marker of Intraplaque Hemorrhage
Matic LP; Iglesias MJ; Vesterlund M; Lengquist M; Hong M-G; Saieed S; Sanchez-Rivera L; Berg M; Razuvaev A; Kronqvist M; Lund K; Caidahl K; Gillgren P; Ponten F; Uhlen M; Schwenk JM; Hansson GK; Paulsson-Berne G; Fagman E; Roy J; Hultgren R; Bergstrom G; Lehtio J; Odeberg J; Hedin U
Article: EUROPEAN HEART JOURNAL. 2018;39(24):2301-2310
Altered metabolism distinguishes high-risk from stable carotid atherosclerotic plaques
Tomas L; Edsfeldt A; Mollet IG; Matic LP; Prehn C; Adamski J; Paulsson-Berne G; Hedin U; Nilsson J; Bengtsson E; Goncalves I; Bjorkbacka H
Article: MOLECULAR THERAPY. 2018;26(4):1040-1055
Local Delivery of miR-21 Stabilizes Fibrous Caps in Vulnerable Atherosclerotic Lesions
Jin H; Li DY; Chernogubova E; Sun C; Busch A; Eken SM; Saliba-Gustafsson P; Winter H; Winski G; Raaz U; Schellinger IN; Simon N; Hegenloh R; Matic LP; Jagodic M; Ehrenborg E; Pelisek J; Eckstein H-H; Hedin U; Backlund A; Maegdefessel L
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2018;38(1):49-63
Extracellular Vesicles Secreted by Atherogenic Macrophages Transfer MicroRNA to Inhibit Cell Migration
Nguyen M-A; Karunakaran D; Geoffrion M; Cheng HS; Tandoc K; Perisic Matic L; Hedin U; Maegdefessel L; Fish JE; Rayner KJ
Article: CIRCULATION JOURNAL. 2017;81(12):1945-1952
Increased Carotid Artery Lesion Inflammation Upon Treatment With the CD137 Agonistic Antibody 2A
Soderstrom LA; Jin H; Caravaca AS; Klement ML; Li Y; Gistera A; Hedin U; Maegdefessel L; Hansson GK; Olofsson PS
Article: JOURNAL OF INTERNAL MEDICINE. 2017;282(5):429-444
Integrative studies implicate matrix metalloproteinase-12 as a culprit gene for large-artery atherosclerotic stroke
Mahdessian H; Matic LP; Lengquist M; Gertow K; Sennblad B; Baldassarre D; Veglia F; Humphries SE; Rauramaa R; de Faire U; Smit AJ; Giral P; Kurl S; Mannarino E; Tremoli E; Hamsten A; Eriksson P; Hedin U; Malarstig A
Article: PLOS GENETICS. 2017;13(5):e1006750
TCF21 and the environmental sensor aryl-hydrocarbon receptor cooperate to activate a pro-inflammatory gene expression program in coronary artery smooth muscle cells
Kim JB; Pjanic M; Trieu N; Miller CL; Iyer D; Liu B; Wang T; Sazonova O; Carcamo-Orive I; Matic LP; Maegdefessel L; Hedin U; Quertermous T
Article: JOURNAL OF CLINICAL INVESTIGATION. 2017;127(4):1546-1560
Extracellular matrix proteomics identifies molecular signature of symptomatic carotid plaques
Langley SR; Willeit K; Didangelos A; Matic LP; Skroblin P; Barallobre-Barreiro J; Lengquist M; Rungger G; Kapustin A; Kedenko L; Molenaar C; Lu R; Barwari T; Suna G; Yin X; Iglseder B; Paulweber B; Willeit P; Shalhoub J; Pasterkamp G; Davies AH; Monaco C; Hedin U; Shanahan CM; Willeit J; Kiechl S; Mayr M
Article: JOURNAL OF INTERNAL MEDICINE. 2017;281(4):383-397
Vaccination against T-cell epitopes of native ApoB100 reduces vascular inflammation and disease in a humanized mouse model of atherosclerosis
Gistera A; Hermansson A; Strodthoff D; Klement ML; Hedin U; Fredrikson GN; Nilsson J; Hansson GK; Ketelhuth DFJ
Article: JOURNAL OF VASCULAR ACCESS. 2017;18(Suppl. 1):110-113
Upper-arm hemodialysis access in Sweden
Hedin U; Welander G
Article: CIRCULATION RESEARCH. 2017;120(4):633-644
MicroRNA-210 Enhances Fibrous Cap Stability in Advanced Atherosclerotic Lesions
Eken SM; Jin H; Chernogubova E; Li Y; Simon N; Sun C; Korzunowicz G; Busch A; Backlund A; Osterholm C; Razuvaev A; Renne T; Eckstein HH; Pelisek J; Eriksson P; Diez MG; Matic LP; Schellinger IN; Raaz U; Leeper NJ; Hansson GK; Paulsson-Berne G; Hedin U; Maegdefessel L
Article: NATURE MEDICINE. 2016;22(10):1140-1150
Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation
Stellos K; Gatsiou A; Stamatelopoulos K; Matic LP; John D; Lunella FF; Jae N; Rossbach O; Amrhein C; Sigala F; Boon RA; Fuertig B; Manavski Y; You X; Uchida S; Keller T; Boeckel J-N; Franco-Cereceda A; Maegdefessel L; Chen W; Schwalbe H; Bindereif A; Eriksson P; Hedin U; Zeiher AM; Dimmeler S
Article: PULMONARY CIRCULATION. 2016;6(3):347-359
Versican accumulates in vascular lesions in pulmonary arterial hypertension
Chang Y-T; Chan CK; Eriksson I; Johnson PY; Cao X; Westoo C; Norvik C; Andersson-Sjoland A; Westergren-Thorsson G; Johansson S; Hedin U; Kjellen L; Wight TN; Tran-Lundmark K
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2016;36(9):1947-1961
Phenotypic Modulation of Smooth Muscle Cells in Atherosclerosis Is Associated With Downregulation of LMOD1, SYNPO2, PDLIM7, PLN, and SYNM
Matic LP; Rykaczewska U; Razuvaev A; Sabater-Lleal M; Lengquist M; Miller CL; Ericsson I; Rohl S; Kronqvist M; Aldi S; Magne J; Paloschi V; Vesterlund M; Li Y; Jin H; Diez MG; Roy J; Baldassarre D; Veglia F; Humphries SE; de Faire U; Tremoli E; Odeberg J; Vukojevic V; Lehtio J; Maegdefessel L; Ehrenborg E; Paulsson-Berne G; Hansson GK; Lindeman JHN; Eriksson P; Quertermous T; Hamsten A; Hedin U
Article: NATURE. 2016;536(7614):86-90
CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis
Kojima Y; Volkmer J-P; McKenna K; Civelek M; Lusis AJ; Miller CL; Direnzo D; Nanda V; Ye J; Connolly AJ; Schadt EE; Quertermous T; Betancur P; Maegdefessel L; Matic LP; Hedin U; Weissman IL; Leeper NJ
Article: NATURE COMMUNICATIONS. 2016;7:12092
Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci
Miller CL; Pjanic M; Wang T; Nguyen T; Cohain A; Lee JD; Perisic L; Hedin U; Kundu RK; Majmudar D; Kim JB; Wang O; Betsholtz C; Ruusalepp A; Franzen O; Assimes TL; Montgomery SB; Schadt EE; Bjorkegren JLM; Quertermous T
Article: SCIENCE ADVANCES. 2016;2(7):e1600224
Targeting macrophage necroptosis for therapeutic and diagnostic interventions in atherosclerosis
Karunakaran D; Geoffrion M; Wei L; Gan W; Richards L; Shangari P; DeKemp EM; Beanlands RA; Perisic L; Maegdefessel L; Hedin U; Sad S; Guo L; Kolodgie FD; Virmani R; Ruddy T; Rayner KJ
Article: ONCOTARGET. 2016;7(26):39486-39496
Heparanase expression upregulates platelet adhesion activity and thrombogenicity
Cui H; Tan Y-X; Osterholm C; Zhang X; Hedin U; Vlodavsky I; Li J-P
Article: SCIENTIFIC REPORTS. 2016;6:28337
Neil3-dependent base excision repair regulates lipid metabolism and prevents atherosclerosis in Apoe-deficient mice
Skarpengland T; Holm S; Scheffler K; Gregersen I; Dahl TB; Suganthan R; Segers FM; Ostlie I; Otten JJT; Luna L; Ketelhuth DFJ; Lundberg AM; Neurauter CG; Hildrestrand G; Skjelland M; Bjorndal B; Svardal AM; Iversen PO; Hedin U; Nygard S; Olstad OK; Krohg-Sorensen K; Slupphaug G; Eide L; Kusnierczyk A; Folkersen L; Ueland T; Berge RK; Hansson GK; Biessen EAL; Halvorsen B; Bjoras M; Aukrust P
Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2016;5(5):e003031
NLRP3 Inflammasome Expression and Activation in Human Atherosclerosis
Varghese GP; Folkersen L; Strawbridge RJ; Halvorsen B; Yndestad A; Ranheim T; Krohg-Sorensen K; Skjelland M; Espevik T; Aukrust P; Lengquist M; Hedin U; Jansson J-H; Fransen K; Hansson GK; Eriksson P; Sirsjo A
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2016;36(5):942-951
miRNA Targeting of Oxysterol-Binding Protein-Like 6 Regulates Cholesterol Trafficking and Efflux
Ouimet M; Hennessy EJ; van Solingen C; Koelwyn GJ; Hussein MA; Ramkhelawon B; Rayner KJ; Temel RE; Perisic L; Hedin U; Maegdefessel L; Garabedian MJ; Holdt LM; Teupser D; Moore KJ
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2016;36(5):972-983
Functional Analysis of a Novel Genome-Wide Association Study Signal in SMAD3 That Confers Protection From Coronary Artery Disease
Turner AW; Martinuk A; Silva A; Lau P; Nikpay M; Eriksson P; Folkersen L; Perisic L; Hedin U; Soubeyrand S; McPherson R
Article: JOURNAL OF INTERNAL MEDICINE. 2016;279(3):293-308
Gene expression signatures, pathways and networks in carotid atherosclerosis
Perisic L; Aldi S; Sun Y; Folkersen L; Razuvaev A; Roy J; Lengquist M; Akesson S; Wheelock CE; Maegdefessel L; Gabrielsen A; Odeberg J; Hansson GK; Paulsson-Berne G; Hedin U
Article: CIRCULATION RESEARCH. 2016;118(2):230-240
CDKN2B Regulates TGFβ Signaling and Smooth Muscle Cell Investment of Hypoxic Neovessels
Nanda V; Downing KP; Ye J; Xiao S; Kojima Y; Spin JM; DiRenzo D; Nead KT; Connolly AJ; Dandona S; Perisic L; Hedin U; Maegdefessel L; Dalman J; Guo L; Zhao X; Kolodgie FD; Virmani R; Davis HRJ; Leeper NJ
Article: GENOMICS DATA. 2015;5:36-37
Coronary artery disease associated transcription factor TCF21 regulates smooth muscle precursor cells that contribute to the fibrous cap
Nurnberg ST; Cheng K; Raiesdana A; Kundu R; Miller CL; Kim JB; Arora K; Carcamo-Oribe I; Xiong Y; Tellakula N; Nanda V; Murthy N; Boisvert WA; Hedin U; Perisic L; Aldi S; Maegdefessel L; Pjanic M; Owens GK; Tallquist MD; Quertermous T
Article: JOURNAL OF CARDIOVASCULAR SURGERY. 2015;56(4):599-605
Endovascular treatment of true and false aneurysms in hemodialysis access
Heidin U; Engstrom J; Roy J
Article: CIRCULATION RESEARCH. 2015;117(3):266-278
Macrophage Mitochondrial Energy Status Regulates Cholesterol Efflux and Is Enhanced by Anti-miR33 in Atherosclerosis
Karunakaran D; Thrush AB; My-Anh N; Richards L; Geoffrion M; Singaravelu R; Ramphos E; Shangari P; Ouimet M; Pezacki JP; Moore KJ; Perisic L; Maegdefessel L; Hedin U; Harper M-E; Rayner KJ
Article: CARDIOVASCULAR RESEARCH. 2015;107(1):20-31
Perlecan heparan sulfate deficiency impairs pulmonary vascular development and attenuates hypoxic pulmonary hypertension
Chang Y-T; Tseng C-N; Tannenberg P; Eriksson L; Yuan K; Perez VADJ; Lundberg J; Lengquist M; Botusan IR; Catrina S-B; Tran P-K; Hedin U; Tran-Lundmark K
Article: PLOS GENETICS. 2015;11(5):e1005155
Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells That Contribute to the Fibrous Cap
Nurnberg ST; Cheng K; Raiesdana A; Kundu R; Miller CL; Kim JB; Arora K; Carcamo-Oribe I; Xiong Y; Tellakula N; Nanda V; Murthy N; Boisvert WA; Hedin U; Perisic L; Aldi S; Maegdefessel L; Pjanic M; Owens GK; Tallquist MD; Quertermous T
Article: THROMBOSIS AND HAEMOSTASIS. 2015;113(4):813-825
Platelet adhesion on endothelium early after vein grafting mediates leukocyte recruitment and intimal hyperplasia in a murine model
Tseng C-N; Chang Y-T; Lengquist M; Kronqvist M; Hedin U; Eriksson EE
Article: THROMBOSIS RESEARCH. 2015;135(3):443-448
Preoperative hypofibrinogenemia is associated with increased intraoperative bleeding in ruptured abdominal aortic aneurysms
Montan C; Johansson F; Hedin U; Wahlgren CM
Article: JOURNAL OF CELLULAR PHYSIOLOGY. 2015;230(2):482-487
Perlecan Heparan Sulfate Is Required for the Inhibition of Smooth Muscle Cell Proliferation by All-trans-Retinoic Acid
Tran-Lundmark K; Tannenberg P; Rauch BH; Ekstrand J; Tran P-K; Hedin U; Kinsella MG
Article: PLOS ONE. 2015;10(3):e0122067
Schip1 Is a Novel Podocyte Foot Process Protein that Mediates Actin Cytoskeleton Rearrangements and Forms a Complex with Nherf2 and Ezrin
Perisic L; Rodriguez PQ; Hultenby K; Sun Y; Lal M; Betsholtz C; Uhlen M; Wernerson A; Hedin U; Pikkarainen T; Tryggvason K; Patrakka J
Article: JOURNAL OF VASCULAR RESEARCH. 2015;52(1):41-52
Glucagon-Like Peptide-1 Receptor Activation Does Not Affect Re-Endothelialization but Reduces Intimal Hyperplasia via Direct Effects on Smooth Muscle Cells in a Nondiabetic Model of Arterial Injury
Eriksson L; Saxelin R; Rohl S; Roy J; Caidahl K; Nystrom T; Hedin U; Razuvaev A
Article: JOURNAL OF VASCULAR ACCESS. 2015;16:S87-S92
Long-term results of PTFE grafts
Hedin U
Article: CONTRAST MEDIA & MOLECULAR IMAGING. 2015;10(1):37-42
Glycolaldehyde and maleyl conjugated human serum albumin as potential macrophage-targeting carriers for molecular imaging purposes
Gustafsson B; Hedin U; Caidahl K
Article: JOURNAL OF CARDIOVASCULAR SURGERY. 2014;55(6):793-801
Vascular access: a never-ending story
Hedin U
Article: CANADIAN JOURNAL OF CARDIOLOGY. 2014;30(11):1444-1451
Perlecan Heparan Sulfate Proteoglycan Is a Critical Determinant of Angiogenesis in Response to Mouse Hind-Limb Ischemia
Qiang B; Lim SY; Lekas M; Kuliszewski MA; Wolff R; Osherov AB; Rudenko D; Leong-Poi H; Noyan H; Husain M; Tran K; Tryggvason K; Hedin U; Tran-Lundmark K; Strauss BH
Article: JOURNAL OF INTERNAL MEDICINE. 2014;276(5):525-536
The collagen cross-linking enzyme lysyl oxidase is associated with the healing of human atherosclerotic lesions
Ovchinnikova OA; Folkersen L; Persson J; Lindeman JHN; Ueland T; Aukrust P; Gavrisheva N; Shlyakhto E; Paulsson-Berne G; Hedin U; Olofsson PS; Hansson GK
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2014;44(10):3081-3092
Innate immune receptor NOD2 promotes vascular inflammation and formation of lipid-rich necrotic cores in hypercholesterolemic mice
Johansson ME; Zhang X-Y; Edfeldt K; Lundberg AM; Levin MC; Boren J; Li W; Yuan X-M; Folkersen L; Eriksson P; Hedin U; Low H; Sviridov D; Rios FJ; Hansson GK; Yan Z-Q
Article: JOURNAL OF THE ROYAL SOCIETY INTERFACE. 2014;11(97):20140403
Synergy between shear-induced migration and secondary flows on red blood cells transport in arteries: considerations on oxygen transport
Biasetti J; Spazzini PG; Hedin U; Gasser TC
Article: AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 2014;307(3):H337-H345
Heparan sulfate side chains have a critical role in the inhibitory effects of perlecan on vascular smooth muscle cell response to arterial injury
Gotha L; Lim SY; Osherov AB; Wolff R; Qiang B; Erlich I; Nili N; Pillarisetti S; Chang Y-T; Tran P-K; Tryggvason K; Hedin U; Tran-Lundmark K; Advani SL; Gilbert RE; Strauss BH
Article: JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY. 2014;25(5):789-796.e7
Early Changes of Gene Expression Profiles in the Rat Model of Arterial Injury
Fedorov A; Kostareva A; Raud J; Roy J; Hedin U; Razuvaev A
Article: JOURNAL OF CLINICAL INVESTIGATION. 2014;124(3):1083-1097
Cyclin-dependent kinase inhibitor 2B regulates efferocytosis and atherosclerosis
Kojima Y; Downing K; Kundu R; Miller C; Dewey F; Lancero H; Raaz U; Perisic L; Hedin U; Schadt E; Maegdefessel L; Quertermous T; Leeper NJ
Article: PLOS GENETICS. 2014;10(3):e1004263
Coronary Heart Disease-Associated Variation in TCF21 Disrupts a miR-224 Binding Site and miRNA-Mediated Regulation
Miller CL; Haas U; Diaz R; Leeper NJ; Kundu RK; Patlolla B; Assimes TL; Kaiser FJ; Perisic L; Hedin U; Maegdefessel L; Schunkert H; Erdmann J; Quertermous T; Sczakiel G
Article: PLOS ONE. 2014;9(6):e98904
Contribution of Endothelial Injury and Inflammation in Early Phase to Vein Graft Failure: The Causal Factors Impact on the Development of Intimal Hyperplasia in Murine Models
Tseng C-N; Karlof E; Chang Y-T; Lengquist M; Rotzius P; Berggren P-O; Hedin U; Eriksson EE
Article: JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS. 2013;27:226-238
Identification of carotid plaque tissue properties using an experimental-numerical approach
Heiland VM; Forsell C; Roy J; Hedin U; Gasser TC
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2013;33(10):2432-2443
Profiling of Atherosclerotic Lesions by Gene and Tissue Microarrays Reveals PCSK6 as a Novel Protease in Unstable Carotid Atherosclerosis
Perisic L; Hedin E; Razuvaev A; Lengquist M; Osterholm C; Folkersen L; Gillgren P; Paulsson-Berne G; Ponten F; Odeberg J; Hedin U
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2013;33(9):2193-2201
NOD2-Mediated Innate Immune Signaling Regulates the Eicosanoids in Atherosclerosis
Liu H-Q; Zhang X-Y; Edfeldt K; Nijhuis MO; Idborg H; Back M; Roy J; Hedin U; Jakobsson P-J; Laman JD; de Kleijn DP; Pasterkamp G; Hansson GK; Yan Z-Q
Article: ATHEROSCLEROSIS. 2013;226(1):67-73
Increased expression of heparanase in symptomatic carotid atherosclerosis
Osterholm C; Folkersen L; Lengquist M; Ponten F; Renne T; Li JP; Hedin U
Article: CIRCULATION-GENOMIC AND PRECISION MEDICINE. 2012;5(6):656-665
Identification of the BCAR1-CFDP1-TMEM170A Locus as a Determinant of Carotid Intima-Media Thickness and Coronary Artery Disease Risk
Gertow K; Sennblad B; Strawbridge RJ; Oehrvik J; Zabaneh D; Shah S; Veglia F; Fava C; Kavousi M; McLachlan S; Kivimaeki M; Bolton JL; Folkersen L; Gigante B; Leander K; Vikstrom M; Larsson M; Silveira A; Deanfield J; Voight BF; Fontanillas P; Sabater-Lleal M; Colombo GI; Kumari M; Langenberg C; Wareham NJ; Uitterlinden AG; Gabrielsen A; Hedin U; Franco-Cereceda A; Nyyssonen K; Rauramaa R; Tuomainen T-P; Savonen K; Smit AJ; Giral P; Mannarino E; Robertson CM; Talmud PJ; Hedblad B; Hofman A; Erdmann J; Reilly MP; O'Donnell CJ; Farrall M; Clarke R; Franzosi MG; Seedorf U; Syvanen A-C; Hansson GK; Eriksson P; Samani NJ; Watkins H; Price JF; Hingorani AD; Melander O; Witteman JCM; Baldassarre D; Tremoli E; de Faire U; Humphries SE; Hamsten A
Article: ATHEROSCLEROSIS. 2012;225(2):491-496
High plasma adiponectin concentration is associated with all-cause mortality in patients with carotid atherosclerosis
Persson J; Folkersen L; Ekstrand J; Helleberg J; Gabrielsen A; Lundman P; Hedin U; Paulsson-Berne G
Article: ATHEROSCLEROSIS. 2012;224(1):266-273
Increased levels of the homeostatic chemokine CXCL13 in human atherosclerosis - Potential role in plaque stabilization
Smedbakken LM; Halvorsen B; Daissormont I; Ranheim T; Michelsen AE; Skjelland M; Sagen EL; Folkersen L; Krohg-Sorensen K; Russell D; Holm S; Ueland T; Fevang B; Hedin U; Yndestad A; Gullestad L; Hansson GK; Biessen EA; Aukrust P
Article: CIRCULATION. 2012;126(8):952-962
Toll-Like Receptor 7 Protects From Atherosclerosis by Constraining "Inflammatory" Macrophage Activation
Salagianni M; Galani IE; Lundberg AM; Davos CH; Varela A; Gavriil A; Lyytikainen L-P; Lehtimaki T; Sigala F; Folkersen L; Gorgoulis V; Lenglet S; Montecucco F; Mach F; Hedin U; Hansson GK; Monaco C; Andreakos E
Article: AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY. 2012;302(11):L1159-L1166
Antenatal imatinib treatment reduces pulmonary vascular remodeling in a rat model of congenital diaphragmatic hernia
Chang Y-T; Uggla AR; Osterholm C; Phan-Kiet T; Eklof A-C; Lengquist M; Hedin U; Tran-Lundmark K; Frenckner B
Article: MOLECULAR MEDICINE. 2012;18(4):669-675
Prediction of Ischemic Events on the Basis of Transcriptomic and Genomic Profiling in Patients Undergoing Carotid Endarterectomy
Folkersen L; Persson J; Ekstrand J; Agardh HE; Hansson GK; Gabrielsen A; Hedin U; Paulsson-Berne G
Article: ATHEROSCLEROSIS. 2012;220(1):102-109
The expression of IGFs and IGF binding proteins in human carotid atherosclerosis, and the possible role of IGF binding protein-1 in the regulation of smooth muscle cell proliferation
Wang J; Razuvaev A; Folkersen L; Hedin E; Roy J; Brismar K; Hedin U
Article: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2011;42(6):722-730
Correlations Between Clinical Variables and Gene-expression Profiles in Carotid Plaque Instability
Razuvaev A; Ekstrand J; Folkersen L; Agardh H; Markus D; Swedenborg J; Hansson GK; Gabrielsen A; Paulsson-Berne G; Roy J; Hedin U
Article: CIRCULATION. 2011;124(22):2433-7
Identification of a danger-associated peptide from apolipoprotein B100 (ApoBDS-1) that triggers innate proatherogenic responses.
Ketelhuth DFJ; Rios FJO; Wang Y; Liu H; Johansson ME; Fredrikson GN; Hedin U; Gidlund M; Nilsson J; Hansson GK; Yan Z-Q
Article: ATHEROSCLEROSIS. 2011;215(2):411-416
12-and 15-lipoxygenases in human carotid atherosclerotic lesions: Associations with cerebroyascular symptoms
Gertow K; Nobili E; Folkersen L; Newman JW; Pedersen TL; Ekstrand J; Swedenborg J; Kuehn H; Wheelock CE; Hansson GK; Hedin U; Haeggstrom JZ; Gabrielsen A
Article: JOURNAL OF INTERNAL MEDICINE. 2011;269(2):200-210
Expression of fatty acid-binding protein 4/aP2 is correlated with plaque instability in carotid atherosclerosis
Agardh HE; Folkersen L; Ekstrand J; Marcus D; Swedenborg J; Hedin U; Gabrielsen A; Paulsson-Berne G
Article: CIRCULATION-GENOMIC AND PRECISION MEDICINE. 2010;3(4):365-373
Association of Genetic Risk Variants With Expression of Proximal Genes Identifies Novel Susceptibility Genes for Cardiovascular Disease
Folkersen L; van't Hooft F; Chernogubova E; Agardh HE; Hansson GK; Hedin U; Liska J; Syvanen A-C; Paulssson-Berne G; Franco-Cereceda A; Hamsten A; Gabrielsen A; Eriksson P
Article: JOURNAL OF MOLECULAR MEDICINE-JMM. 2010;88(8):795-806
Thromboxane synthase expression and thromboxane A₂ production in the atherosclerotic lesion
Gabrielsen A; Qiu H; Back M; Hamberg M; Hemdahl A-L; Agardh H; Folkersen L; Swedenborg J; Hedin U; Paulsson-Berne G; Haeggstrom JZ; Hansson GK
Article: JOURNAL OF VASCULAR SURGERY. 2010;52(1):167-175
Tissue factor pathway inhibitor-2 is induced by fluid shear stress in vascular smooth muscle cells and affects cell proliferation and survival
Ekstrand J; Razuvaev A; Folkersen L; Roy J; Hedin U
Article: LAKARTIDNINGEN. 2010;107(21):1356-1357
[Ethics Review Boards discriminate the most severely ill--Swedish researchers are prevented to participate in an international study].
Björck M; Berg B; Hedin U; Wingren U
Article: ANNALS OF BIOMEDICAL ENGINEERING. 2010;38(2):380-390
Hemodynamics of the Normal Aorta Compared to Fusiform and Saccular Abdominal Aortic Aneurysms with Emphasis on a Potential Thrombus Formation Mechanism
Biasetti J; Gasser TC; Auer M; Hedin U; Labruto F
Article: JOURNAL OF VASCULAR SURGERY. 2009;50(2):388-395
Mast cells associate with neovessels in the media and adventitia of abdominal aortic aneurysms
Mayranpaa MI; Trosien JA; Fontaine V; Folkesson M; Kazi M; Eriksson P; Swedenborg J; Hedin U
Article: JOURNAL OF MOLECULAR MEDICINE-JMM. 2009;87(4):337-346
Genetic variants of TNFSF4 and risk for carotid artery disease and stroke
Olofsson PS; Soderstrom LA; Jern C; Sirsjoe A; Ria M; Sundler E; de Faire U; Wiklund PG; Ohrvik J; Hedin U; Paulsson-Berne G; Hamsten A; Eriksson P; Hansson GK
Article: JOURNAL OF NUCLEAR MEDICINE. 2008;49(10):1601-1605
High ¹⁸F-FDG Uptake in Synthetic Aortic Vascular Grafts on PET/CT in Symptomatic and Asymptomatic Patients
Wasselius J; Malmstedt J; Kalin B; Larsson S; Sundin A; Hedin U; Jacobsson H
Article: ATHEROSCLEROSIS. 2008;199(2):310-316
Noninvasive real-time imaging of intima thickness after rat carotid artery balloon injury using ultrasound biomicroscopy
Razuvaev A; Lund K; Roy J; Hedin U; Caidahl K
Article: CIRCULATION RESEARCH. 2008;103(1):43-52
Heparan sulfate in perlecan promotes mouse atherosclerosis -: Roles in lipid permeability, lipid retention, and smooth muscle cell proliferation
Tran-Lundmark K; Tran P-K; Paulsson-Berne G; Friden V; Soininen R; Tryggvason K; Wight TN; Kinsella MG; Boren J; Hedin U
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2008;28(5):975-982
Variants of the interferon regulatory factor 5 gene regulate expression of IRF5 mRNA in atherosclerotic tissue but are not associated with myocardial infarction
Malarstig A; Sigurdsson S; Eriksson P; Paulsson-Berne G; Hedin U; Wallentin L; Siegbahn A; Hamsten A; Syvanen A-C
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2008;28(5):1005-1011
A potential role of the CXC chemokine GROα in atherosclerosis and plaque destabilization -: Downregulatory effects of statins
Breland UM; Halvorsen B; Hol J; Oie E; Paulsson-Berne G; Yndestad A; Smith C; Otterdal K; Hedin U; Waehre T; Sandberg WJ; Froland SS; Haraldsen G; Gullestad L; Damas JK; Hansson GK; Aukrust P
Article: CIRCULATION. 2008;117(10):1292-1301
CD137 is expressed in human atherosclerosis and promotes development of plaque inflammation in hypercholesterolemic mice
Olofsson PS; Soderstrom LA; Wagsater D; Sheikine Y; Ocaya P; Lang F; Rabu C; Chen L; Rudling M; Aukrust P; Hedin U; Paulsson-Berne G; Sirsjoe A; Hansson GK
Article: THROMBOSIS AND HAEMOSTASIS. 2007;98(2):427-433
Presence of NGAL/MMP-9 complexes in human abdominal aortic aneurysms
Folkesson M; Kazi M; Zh C; Silveira A; Hemclahl A-L; Harristen A; Hedin U; Swedenborg J; Eriksson P
Article: JOURNAL OF VASCULAR SURGERY. 2007;46(1):108-115
The cyclolignan picropodophyllin attenuates intimal hyperplasia after rat carotid balloon injury by blocking insulin-like growth factor-1 receptor signaling
Razuvaev A; Henderson B; Girnita L; Larsson O; Axelson M; Hedin U; Roy J
Article: AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 2007;292(6):H3158-H3163
Cardioprotective effect of rosuvastatin in vivo is dependent on inhibition of geranylgeranyl pyrophosphate and altered RhoA membrane translocation
Bulhak A; Roy J; Hedin U; Sjoquist P-O; Pernow J
Article: ATHEROSCLEROSIS. 2007;190(2):264-270
Reduced perlecan expression and accumulation in human carotid atherosclerotic lesions
Tran P-K; Agardh HE; Tran-Lundmark K; Ekstrand J; Roy J; Henderson B; Gabrielsen A; Hansson GK; Swedenborg J; Paulsson-Berne G; Hedin U
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2006;103(21):8161-8166
Expression of 5-lipoxygenase and leukotriene A₄ hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instability
Qiu H; Gabrielsen A; Agardh HE; Wan M; Wetterholm A; Wong C-H; Hedin U; Swedenborg J; Hansson GK; Samuelsson B; Paulsson-Berne G; Haeggstrom JZ
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2006;26(1):136-142
Expression of neutrophil gelatinase-associated lipocalin in atherosclerosis and myocardial infarction
Hemdahl AL; Gabrielsen A; Zhu CY; Eriksson P; Hedin U; Kastrup J; Thorén P; Hansson GK
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2005;25(7):e113-e116
The antiviral cytomegalovirus inducible gene 5/viperin is expressed in atherosclerosis and regulated by proinflammatory agents
Olofsson PS; Jatta K; Wågsäter D; Gredmark S; Hedin U; Paulsson-Berne G; Söderberg-Nauclér C; Hansson GK; Sirsjö A
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2005;25(7):1341-1346
Difference in matrix-degrading protease expression and activity between thrombus-free and thrombus-covered wall of abdominal aortic aneurysm
Kazi M; Zhu CY; Roy J; Paulsson-Berne G; Hamsten A; Swedenborg J; Hedin U; Eriksson P
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2005;25(4):723-728
Powerful inflammatory properties of large vein endothelium in vivo
Eriksson EE; Karlof E; Lundmark K; Rotzius P; Hedin U; Xie X
Article: CARDIOVASCULAR RESEARCH. 2005;65(2):535-545
Allogenic immune response promotes the accumulation of host-derived smooth muscle cells in transplant arteriosclerosis
Religa P; Bojakowski K; Bojakowska M; Gaciong Z; Thyberg J; Hedin U
Article: PROTEIN JOURNAL. 2004;23(4):263-271
Identification of Endothelial Proteins by MALDI-MS Using a Compact Disc Microfluidic System
Hirschberg D; Tryggvason S; Gustafsson M; Bergman T; Swedenborg J; Hedin U; Jornvall H
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2004;24(4):750-755
CXCL16/SR-PSOX is an interferon-γ-regulated chemokine and scavenger receptor expressed in atherosclerotic lesions
Wuttge DM; Zhou XH; Sheikine Y; Wågsäter D; Stemme V; Hedin U; Stemme S; Hansson GK; Sirsjö A
Article: CIRCULATION RESEARCH. 2004;94(4):550-558
Increased intimal hyperplasia and smooth muscle cell proliferation in transgenic mice with heparan sulfate-deficient perlecan
Tran PK; Tran-Lundmark K; Soininen R; Tryggvason K; Thyberg J; Hedin U
Article: MOLECULAR AND CELLULAR BIOCHEMISTRY. 2003;249(1-2):75-83
Arteriosclerosis in rat aortic allografts: Dynamics of cell growth, apoptosis and expression of extracellular matrix proteins
Religa P; Bojakowski K; Gaciong Z; Thyberg J; Hedin U
Article: JOURNAL OF CELLULAR PHYSIOLOGY. 2002;193(3):365-372
Inhibition of rat smooth muscle cell adhesion and proliferation by non-anticoagulant heparins
Kazi M; Lundmark K; Religa P; Gouda I; Larm O; Ray A; Swedenborg J; Hedin U
Article: TRANSPLANTATION. 2002;74(9):1310-1315
Smooth-muscle progenitor cells of bone marrow origin contribute to the development of neointimal thickenings in rat aortic allografts and injured rat carotid arteries
Religa P; Bojakowski K; Maksymowicz M; Bojakowska M; Sirsjo A; Gaciong Z; Olszewski W; Hedin U; Thyberg J
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2002;277(15):12741-12748
Recombinant human laminin-10 (α5,β1,γ1) -: Production, purification, and migration-promoting activity on vascular endothelial cells
Doi M; Thyboll J; Kortesmaa J; Jansson K; Iivanainen A; Parvardeh M; Timpl R; Hedin U; Swedenborg J; Tryggvason K
Article: EXPERIMENTAL CELL RESEARCH. 2002;273(2):169-177
Fibronectin promotes cell cycle entry in smooth muscle cells in primary culture
Roy J; Tran PK; Religa P; Kazi M; Henderson B; Lundmark K; Hedin U
Article: ATHEROSCLEROSIS. 2002;160(1):215-222
Enhanced vasoconstrictor effect of big endothelin-1 in patients with atherosclerosis:: relation to conversion to endothelin-1
Böhm F; Johansson BL; Hedin U; Alving K; Pernow J
Article: JOURNAL OF CELLULAR PHYSIOLOGY. 2001;188(1):67-74
Perlecan inhibits smooth muscle cell adhesion to fibronectin: Role of heparan sulfate
Lundmark K; Tran PK; Kinsella MG; Clowes AW; Wight TN; Hedin U
Article: DIFFERENTIATION. 2001;67(1-2):50-58
Phenotypic modulation of arterial smooth muscle coils is associated with prolonged activation of Erk1/2
Roy J; Kazi M; Hedin U; Thyberg J
Article: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2000;20(5):419-426
Fucoidan inhibits smooth muscle cell proliferation and reduces mitogen-activated protein kinase activity
Religa P; Kazi M; Thyberg J; Gaciong Z; Swedenborg J; Hedin J
Article: TRANSPLANTATION. 2000;70(1):65-72
Arteriosclerosis in rat aortic allografts: Early changes in endothelial integrity and smooth muscle phenotype
Bojakowski K; Religa P; Bojakowska M; Hedin U; Gaciong Z; Thyberg J
Article: ATHEROSCLEROSIS. 1999;145(1):33-43
Cytokine expression in advanced human atherosclerotic plaques:: dominance of pro-inflammatory (Th1) and macrophage-stimulating cytokines
Frostegård J; Ulfgren AK; Nyberg P; Hedin U; Swedenborg J; Andersson U; Hansson GK
Article: CIRCULATION RESEARCH. 1998;83(3):305-313
Heparan sulfate proteoglycans mediate a potent inhibitory signal for migration of vascular smooth muscle cells
Koyama N; Kinsella MG; Wight TN; Hedin U; Clowes AW
Article: JOURNAL OF VASCULAR SURGERY. 1998;27(3):512-520
Heparin inhibits thrombin-induced mitogen-activated protein kinase signaling in arterial smooth muscle cells
Hedin U; Daum G; Clowes AW
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 1997;17(10):2257-2263
Expression of phospholipase A(2) isoforms in human normal and atherosclerotic arterial wall
Elinder LS; Dumitrescu A; Larsson P; Hedin U; Frostegard J; Claesson HE
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 1997;17(10):1977-1984
Role of tyrosine kinases in extracellular matrix-mediated modulation of arterial smooth muscle cell phenotype
Hedin U; Thyberg J; Roy J; Dumitrescu A; Tran PK
Article: LABORATORY INVESTIGATION. 1997;77(1):93-101
Expression of caveolae on the surface of rat arterial smooth muscle cells is dependent on the phenotypic state of the cells
Thyberg J; Roy J; Tran PK; Blomgren K; Dumitrescu A; Hedin U
Article: JOURNAL OF CELLULAR PHYSIOLOGY. 1997;172(1):109-116
Disruption of integrin alpha(5)beta(1) signaling does not impair PDGF-BB-Mediated stimulation of the extracellular signal-regulated kinase pathway in smooth muscle cells
Hedin U; Daum G; Clowes AW
Article: CIRCULATION RESEARCH. 1997;81(1):17-23
Diverse effects of heparin on mitogen-activated protein kinase-dependent signal transduction in vascular smooth muscle cells
Daum G; Hedin U; Wang YX; Wang T; Clowes AW
Article: JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY. 1997;45(6):837-846
Phenotypic modulation of smooth muscle cells after arterial injury is associated with changes in the distribution of laminin and fibronectin
Thyberg J; Blomgren K; Roy J; Tran PK; Hedin U
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 1996;16(2):187-193
Autocrine induction of DNA synthesis by mechanical injury of cultured smooth muscle cells - Potential role of FGF and PDGF
Calara F; Ameli S; HultgardhNilsson A; Cercek B; Kupfer J; Hedin U; Forrester J; Shah PK; Nilsson J
Article: CELL AND TISSUE RESEARCH. 1995;281(3):421-433
PHENOTYPIC MODULATION OF SMOOTH-MUSCLE CELLS DURING THE FORMATION OF NEOINTIMAL THICKENINGS IN THE RAT CAROTID-ARTERY AFTER BALLOON INJURY - AN ELECTRON-MICROSCOPIC AND STEREOLOGICAL STUDY
THYBERG J; BLOMGREN K; HEDIN U; DRYJSKI M
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Editorial comment: ATHEROSCLEROSIS. 2023;387:117365
The more the merrier: Severe vascular injury increases engagement of smooth muscle cell clones in intimal repair
Hedin U; Chemaly M; Matic L
Editorial comment: CARDIOVASCULAR RESEARCH. 2023;119(5):1100-1102
Smooth muscle cell oligoclonality in vascular disease: same origin, different destinies
Matic L; Chemaly M; Hedin U
Editorial comment: JVS - VASCULAR SCIENCE. 2023;4:100132
We need more vascular research
Dardik A; Curci JA; Tang GL; Hedin U; Sadaghianloo N; Roy TL; Dalman RL
Review: EUROPEAN CARDIOLOGY. 2022;17:e09
Circulating Biomarkers in Lower Extremity Artery Disease
Ziegler L; Hedin U; Gottsater A
Editorial comment: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2021;41(9):2384-2386
Another Notch in the Cap
Hedin U
Review: AMERICAN JOURNAL OF NEURORADIOLOGY. 2021;42(9):1566-1575
Roadmap Consensus on Carotid Artery Plaque Imaging and Impact on Therapy Strategies and Guidelines: An International, Multispecialty, Expert Review and Position Statement
Saba L; Brinjikji W; Spence JD; Wintermark M; Castillo M; Borst GJD; Yang Q; Yuan C; Buckler A; Edjlali M; Saam T; Saloner D; Lal BK; Capodanno D; Sun J; Balu N; Naylor R; Lugt AVD; Wasserman BA; Kooi ME; Wardlaw J; Gillard J; Lanzino G; Hedin U; Mikulis D; Gupta A; DeMarco JK; Hess C; Goethem JV; Hatsukami T; Rothwell P; Brown MM; Moody AR
Corrigendum: SCIENTIFIC REPORTS. 2021;11(1):8852
Author Correction: Expression of CARD8 in human atherosclerosis and its regulation of inflammatory proteins in human endothelial cells.
Paramel GV; Karadimou G; Eremo AG; Ljungberg LU; Hedin U; Olofsson PS; Folkersen L; Paulsson-Berne G; Sirsjö A; Fransén K
Editorial comment: JOURNAL OF INTERNAL MEDICINE. 2020;288(5):489-490
Translation of recent discoveries in cardiovascular disease research to novel therapeutic strategies
Hedin U
Letter: CARDIOVASCULAR DIAGNOSIS AND THERAPY. 2020;10(5):1352-1355
Can COVID19 trigger the plaque vulnerability-a Kounis syndrome warning for "asymptomatic subjects"
Saba L; Gerosa C; Wintermark M; Hedin U; Fanni D; Suri JS; Balestrieri A; Faa G
Review: JOURNAL OF VASCULAR SURGERY. 2019;69(3):944-951
Recent advances in therapeutic targeting of inflammation in atherosclerosis
Hedin U; Matic LP
Other: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2017;53(5):615-616
Jesper Swedenborg In Memoriam
Hedin U; Hultgren R
Editorial comment: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2016;51(5):622
Commentary on 'Plaque Echolucency and the Risk of Ischaemic Stroke in Patients with Asymptomatic Carotid Stenosis Within the First Asymptomatic Carotid Surgery Trial (ACST-1)'
Roy J; Hedin U
Letter: JOURNAL OF VASCULAR ACCESS. 2016;17(1):e3-e4
VORTEC technique in central venous recanalization for haemodialysis access salvage
Tornqvist P; Hedin U; Asciutto G; Engstrom J; Bountouris I; Kristmundsson T; Sterner G; Dias NV
Letter: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2015;179:370-372
Aspirin-triggered 15-epi-lipoxin A₄ signals through FPR2/ALX in vascular smooth muscle cells and protects against intimal hyperplasia after carotid ligation
Petri MH; Laguna-Fernandez A; Tseng C-N; Hedin U; Perretti M; Back M
Corrigendum: PLOS ONE. 2015;10(5):e0126079
Schip1 Is a Novel Podocyte Foot Process Protein that Mediates Actin Cytoskeleton Rearrangements and Forms a Complex with Nherf2 and Ezrin (vol 10, e0122067, 2015)
Perisic L; Rodriguez PQ; Hultenby K; Sun Y; Lal M; Betsholtz C; Uhlen M; Wernerson A; Hedin U; Pikkarainen T; Tryggvason K; Patrakka J
Review: LAKARTIDNINGEN. 2013;110(7):354-357
[Tools for control of bleeding during vascular trauma].
Wahlgren CM; Montán C; Hedin U
Review: LAKARTIDNINGEN. 2011;108(8):406-410
[Hemodialysis access--a vascular surgical problem].
Hedin U
Meeting abstract: JOURNAL OF VASCULAR SURGERY. 2010;51:72S-73S
A Specific Inhibitor of IGF-1 Receptor - Picropodophyllin Can Suppress Atheroma Progression and Has a Stabilizing Effect on Atherosclerotic Lesions in ApoE Deficient Mice
Razuvaev A; Larsson O; Axelson M; Hedin U; Roy J
Meeting abstract: JOURNAL OF VASCULAR SURGERY. 2010;51:80S
Regulation of Endothelin-1 and Endothelin Receptors by Shear Stress in Vascular Smooth Muscle Cells
Ekstrand J; Razuvaev A; Roy J; Hedin U
Meeting abstract: JOURNAL OF VASCULAR SURGERY. 2010;51:79S
A Mouse Model of Vascular Grafting
Tseng C-N; Eriksson E; Hedin U
Review: MOLECULAR BIOSYSTEMS. 2010;6(2):289-304
The use of network analyses for elucidating mechanisms in cardiovascular disease
Diez D; Wheelock AM; Goto S; Haeggstrom JZ; Paulsson-Berne G; Hansson GK; Hedin U; Gabrielsen A; Wheelock CE
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2008;9(1):198
ENHANCED EXPRESSION OF THE CHEMOKINE CXCL1 IN ATHEROSCLEROTIC DISORDERS, DOWN-REGULATORY EFFECTS OF STATIN
Breland UM; Halvorsen B; Hol J; Oie E; Yndestad A; Smith C; Otterdal K; Hedin U; Waehre T; Sandberg W; Froland SS; Haraldsen G; Gullestad L; Hansson GK; Damas JK; Aukrust P
Review: LAKARTIDNINGEN. 2007;104(6):412-414
[Symptomatic carotid stenosis should be treated surgically, not with stenting. Great risks with stents, according to studies].
Swedenborg J; Hedin U; Bergqvist D
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2006;7(3):248
Inflammatory response inhuman atherosclerosis:bike -: Biobank of karolinska endartherectomy
Paulsson-Berne G; Gabrielsen A; Agardh HE; Ekstrand J; Marcus D; Bodin I; Swedenborg J; Hansson GK; Hedin U
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2006;7(3):406
Invariant NKT cells present in human atherosclerotic lesions
Agardh HE; Eriksson P; Tupin E; Kazi M; Hedin U; Olsson A; Hansson GK; Swedenborg J; Paulsson-Berne G
Review: ACTA CHIRURGICA BELGICA. 2004;104(6):606-608
Influence of the intraluminal thrombus in abdominal aortic aneurysms
Swedenborg J; Kazi M; Eriksson R; Hedin U
Review: CURRENT OPINION IN LIPIDOLOGY. 2004;15(5):559-565
Control of smooth muscle cell proliferation in vascular disease
Hedin U; Roy J; Tran PK
Published conference paper: JOURNAL OF VASCULAR SURGERY. 2003;38(6):1283-1292
Influence of intraluminal thrombus on structural and cellular composition of abdominal aortic aneurysm wall
Kazi M; Thyberg J; Religa P; Roy J; Eriksson P; Hedin U; Swedenborg J
Published conference paper: TRANSPLANTATION PROCEEDINGS. 2002;34(2):687-688
Extracellular matrix composition and cellular mechanisms of transplant vasculopathy in rat aortic allografts
Religa P; Bojakowski K; Bojakowska M; Gaciong Z; Thyberg J; Hedin U
Meeting abstract: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY. 2001;33(6):A100
Arteriosclerosis in rat aortic allografts: Dependence of cell phenotype, growth and apoptosis on extracellular matrix composition
Religa P; Bojakowski K; Gaciong Z; Hedin U; Thyberg J
Published conference paper: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY. 2000;36(5 Suppl 1):S418-S420
Enhanced vasoconstrictor response to endothelin-B-receptor stimulation in patients with atherosclerosis
Pernow J; Böhm F; Johansson BL; Hedin U; Rydén L
Review: THROMBOSIS AND HAEMOSTASIS. 1999;82 Suppl 1:23-26
Control of smooth muscle cell proliferation--the role of the basement membrane.
Hedin U; Roy J; Tran PK; Lundmark K; Rahman A
Review: LAKARTIDNINGEN. 1999;96(13):1585-1590
[Intermittent claudication--a major cardiovascular risk factor. Proposed guidelines for investigation and treatment].
Svensson P; Wahlberg E; Hedin U; Ostergren J
Review: LAKARTIDNINGEN. 1997;94(26-27):2481-2484
[Restenosis--elusive shadow of vascular biology. New discoveries set hopes about future therapy].
Hedin U
Review: LAKARTIDNINGEN. 1997;94(14):1276-1283
[Gene therapy in peripheral vascular disease. A future therapeutic method?].
Wahlberg E; Hedin U
Review: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 1997;13(2):101-111
Gene therapy and vascular disease: Potential applications in vascular surgery
Hedin U; Wahlberg E
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Professor/Överläkare, Molekylär medicin och kirurgi, Karolinska Institutet, 2006-

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Ulrika Hahn-Lundström, Renal function decline and optimized planning for kidney replacement therapy

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