Teresa Mortera Blanco

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: JOURNAL OF INTERNAL MEDICINE. 2024;296(1):53-67
Early transfusion patterns improve the Molecular International Prognostic Scoring System (IPSS-M) prediction in myelodysplastic syndromes
Creignou M; Bernard E; Gasparini A; Tranberg A; Todisco G; Moura PL; Ejerblad E; Nilsson L; Garelius H; Antunovic P; Lorenz F; Rasmussen B; Walldin G; Mortera-Blanco T; Jansson M; Tobiasson M; Elena C; Ferrari J; Galli A; Pozzi S; Malcovati L; Edgren G; Crowther MJ; Jaedersten M; Papaemmanuil E; Hellstroem-Lindberg E
Article: BLOOD. 2024;143(11):953-966
Identification and surveillance of rare relapse-initiating stem cells during complete remission after transplantation
Dimitriou M; Mortera-Blanco T; Tobiasson M; Mazzi S; Lehander M; Hoegstrand K; Karimi M; Walldin G; Jansson M; Vonlanthen S; Ljungman P; Langemeijer S; Yoshizato T; Hellstroem-Lindberg E; Woll PS; Jacobsen SEW
Article: CANCER RESEARCH. 2024;84(2):211-225
Erythroid Differentiation Enhances RNA Mis-Splicing in SF3B1-Mutant Myelodysplastic Syndromes with Ring Sideroblasts
Moura PL; Mortera-Blanco T; Hofman IJ; Todisco G; Kretzschmar WW; Bjoerklund A-C; Creignou M; Hagemann-Jensen M; Ziegenhain C; Cabrerizo Granados D; Barbosa I; Walldin G; Jansson M; Ashley N; Mead AJ; Lundin V; Dimitriou M; Yoshizato T; Woll PS; Ogawa S; Sandberg R; Jacobsen SEW; Hellstrom-Lindberg E
Article: CLINICAL CANCER RESEARCH. 2023;29(20):4256-4267
Integrated Genomic and Transcriptomic Analysis Improves Disease Classification and Risk Stratification of MDS with Ring Sideroblasts
Todisco G; Creignou M; Bernard E; Bjorklund A-C; Moura PL; Tesi B; Mortera-Blanco T; Sander B; Jansson M; Walldin G; Barbosa I; Reinsbach SE; Hofman IJ; Nilsson C; Yoshizato T; Dimitriou M; Chang D; Olafsdottir S; Larsson SV; Tobiasson M; Malcovati L; Woll P; Jacobsen SEW; Papaemmanuil E; Hellstroem-Lindberg E
Journal article: HEMASPHERE. 2023;7(Suppl):e22964a1
P713: EXPLORING CLONAL COMPETITION THROUGH 12‐YEAR FOLLOW‐UP OF AN MDS‐RS PATIENT WITH DUAL SF3B1 MUTATIONS
Moura P; Hofman I; Nannya Y; Aliouat A; Mortera‐Blanco T; Yoshizato T; Saiki R; Nakagawa M; Björklund A; Walldin G; Barbosa I; Jansson M; Grasso F; Creignou M; Elvarsdottir E; Woll P; Jacobsen SE; Ogawa S; Lindberg EH
Journal article: LEUKEMIA RESEARCH. 2023;128:107256
UNDERSTANDING CMML BIOLOGY BY INTEGRATIVE ANALYSIS OF EXOME SEQUENCING, RNA SEQUENCING, AND METHYLOME IN A LARGE PATIENT COHORT
Kynning MK; Nannya Y; Todisco G; Yoshizato T; Tesi B; Mortera-Blanco T; Bjorklund A-C; Bruck O; Ohyashiki K; Ishikawa T; Ochi Y; Haferlach T; Mustjoki S; Hellstrom-Lindberg E; Ogawa S; Ungerstedt J
Journal article: LEUKEMIA RESEARCH. 2023;128:107135
ACCELERATED RNA SPLICING DYNAMICS DURING ERYTHROID DIFFERENTIATION AMPLIFY MIS-SPLICING IN SF3B1-MUTANT MDS-RS
Moura P; Mortera-Blanco T; Hofman I; Todisco G; Kretzschmar W; Bjorklund A-C; Creignou M; Hagemann-Jensen M; Ziegenhain C; Granados D; Barbosa I; Walldin G; Jansson M; Mead A; Lundin V; Dimitriou M; Yoshizato T; Woll P; Ogawa S; Sandberg R; Jacobsen SE; Hellstrom-Lindberg E
Journal article: LEUKEMIA RESEARCH. 2023;128:107119
EARLY TRANSFUSION PATTERNS PREDICT OUTCOMES INDEPENDENTLY OF IPSS-M SCORE IN MYELODYSPLASTIC SYNDROMES
Creignou M; Bernard E; Crowther M; Tranberg A; Todisco G; Moura P; Ejerblad E; Nilsson L; Garelius H; Antunovic P; Lorenz F; Rasmussen B; Walldin G; Mortera-Blanco T; Jansson M; Tobiasson M; Edgren G; Jadersten M; Papaemmanuil E; Hellstrom-Lindberg E
Article: BLOOD ADVANCES. 2022;6(10):2992-3005
Patient-specific MDS-RS iPSCs define the mis-spliced transcript repertoire and chromatin landscape of SF3B1-mutant HSPCs
Asimomitis G; G. Deslaurnes A; Kotini AG; Bernard E; Esposito D; Olszewska M; Spyrou N; Ossa JA; Mortera-Blanco T; Koche R; Malcovati L; Ogawa S; Cazzola M; Aaronson SA; Hellstro-Lindberg E; Papaemmanuil E; Nannya Y; Papapetrou EP
Article: NATURE CELL BIOLOGY. 2022;24(3):299-306
Pseudouridine-modified tRNA fragments repress aberrant protein synthesis and predict leukaemic progression in myelodysplastic syndrome
Guzzi N; Muthukumar S; Ciesla M; Todisco G; Ngoc PCT; Madej M; Munita R; Fazio S; Ekstrom S; Mortera-Blanco T; Jansson M; Nannya Y; Cazzola M; Ogawa S; Malcovati L; Hellstrom-Lindberg E; Dimitriou M; Bellodi C
Journal article: BLOOD. 2021;138:146
Integrative Analysis of Primary SF3B1 ^mt Ring Sideroblasts Provides Fundamental Insights into MDS-RS Pathogenesis and Dyserythropoiesis
Moura PL; Mortera-Blanco T; Hofman IJF; Todisco G; Kretzschmar WW; Barbosa I; Bjorklund A-C; Walldin G; Jansson M; Yoshizato T; Woll PS; Jacobsen SEW; Lindberg EH
Journal article: LEUKEMIA RESEARCH. 2021;108:106679.9
O13 Topic: AS01-Diagnosis/AS01c-Molecular aberrations (cytogenetic, genetic, gene expression) WHOLE TRANSCRIPTOME ANALYSIS IDENTIFIES DISTINCT GENE EXPRESSION PROFILES BETWEEN SF3B1MUT AND SF3B1WT MYELODYSPLASTIC SYNDROME WITH RING SIDEROBLASTS
Todisco G; Creignou M; Bernard E; Björklund A-C; Moura P; Jansson M; Barbosa I; Chang D; Venckute S; Walldin G; Tesi B; Mortera-Blanco T; Papaemmanuil E; Hellström-Lindberg E
Article: LEUKEMIA. 2020;34(1):271-282
A three-dimensional in vitro model of erythropoiesis recapitulates erythroid failure in myelodysplastic syndromes
Elvarsdottir EM; Mortera-Blanco T; Dimitriou M; Bouderlique T; Jansson M; Hofman IJF; Conte S; Karimi M; Sander B; Douagi I; Woll PS; Hellstrom-Lindberg E
Article: BLOOD. 2017;130(7):881-890
SF3B1-initiating mutations in MDS-RSs target lymphomyeloid hematopoietic stem cells
Mortera-Blanco T; Dimitriou M; Woll PS; Karimi M; Elvarsdottir E; Conte S; Tobiasson M; Jansson M; Douagi I; Moarii M; Saft L; Papaemmanuil E; Jacobsen SEW; Hellstrom-Lindberg E
Article: ONCOTARGET. 2016;7(45):72685-72698
Perturbed hematopoietic stem and progenitor cell hierarchy in myelodysplastic syndromes patients with monosomy 7 as the sole cytogenetic abnormality
Dimitriou M; Woll PS; Mortera-Blanco T; Karimi M; Wedge DC; Doolittle H; Douagi I; Papaemmanuil E; Jacobsen SEW; Hellstrom-Lindberg E
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2015;171(4):478-490
Aberrant splicing of genes involved in haemoglobin synthesis and impaired terminal erythroid maturation in SF3B1 mutated refractory anaemia with ring sideroblasts
Conte S; Katayama S; Vesterlund L; Karimi M; Dimitriou M; Jansson M; Mortera-Blanco T; Unneberg P; Papaemmanuil E; Sander B; Skoog T; Campbell P; Walfridsson J; Kere J; Hellstrom-Lindberg E
Article: CANCER CELL. 2014;25(6):794-808
Myelodysplastic Syndromes Are Propagated by Rare and Distinct Human Cancer Stem Cells In Vivo
Woll PS; Kjallquist U; Chowdhury O; Doolittle H; Wedge DC; Thongjuea S; Erlandsson R; Ngara M; Anderson K; Deng Q; Mead AJ; Stenson L; Giustacchini A; Duarte S; Giannoulatou E; Taylor S; Karimi M; Scharenberg C; Mortera-Blanco T; Macaulay IC; Clark S-A; Dybedal I; Josefsen D; Fenaux P; Hokland P; Holm MS; Cazzola M; Malcovati L; Tauro S; Bowen D; Boultwood J; Pellagatti A; Pimanda JE; Unnikrishnan A; Vyas P; Goehring G; Schlegelberger B; Tobiasson M; Kvalheim G; Constantinescu SN; Nerlov C; Nilsson L; Campbell PJ; Sandberg R; Papaemmanuil E; Hellstrom-Lindberg E; Linnarsson S; Jacobsen SEW
Journal article: BLOOD. 2013;122(21):4195
Diverse Genetic Lesions In Myelodysplastic Syndromes Originate Exclusively In Rare MDS Stem Cells
Woll P; Kjällquist U; Chowdhury O; Erlandsson R; Doolittle H; Ngara M; Anderson K; Giannoulatou E; Taylor S; Deng Q; Mead AJ; Scharenberg C; Mortera-Blanco T; Macaulay IC; Clark S-A; Josefsen D; Kvalheim G; Göhring G; Schlegelberger B; Tobiasson M; Holm MS; Hokland P; Fenaux P; Nerlov C; Dybedal I; Nilsson L; Sandberg R; Hellström-Lindberg E; Linnarsson S; Jacobsen SEW
Article: LEUKEMIA. 2013;27(4):889-896
The transporter ABCB7 is a mediator of the phenotype of acquired refractory anemia with ring sideroblasts
Nikpour M; Scharenberg C; Liu A; Conte S; Karimi M; Mortera-Blanco T; Giai V; Fernandez-Mercado M; Papaemmanuil E; Hogstrand K; Jansson M; Vedin I; Wainscoat JS; Campbell P; Cazzola M; Boultwood J; Grandien A; Hellstrom-Lindberg E
Article: JOURNAL OF VISUALIZED EXPERIMENTS. 2012;(62):3654
Ex vivo Mimicry of Normal and Abnormal Human Hematopoiesis
Mortera-Blanco T; Rende M; Macedo H; Farah S; Bismarck A; Mantalaris A; Panoskaltsis N
Article: BIOMATERIALS. 2011;32(35):9263-9270
Long-term cytokine-free expansion of cord blood mononuclear cells in three-dimensional scaffolds
Mortera-Blanco T; Mantalaris A; Bismarck A; Aqel N; Panoskaltsis N
Article: BIOMATERIALS. 2010;31(8):2243-2251
The development of a three-dimensional scaffold for ex vivo biomimicry of human acute myeloid leukaemia
Blanco TM; Mantalaris A; Bismarck A; Panoskaltsis N
Journal article: BLOOD. 2009;114(22):503
Long-Term in Vitro Cytokine-Free and Serum-Free Culture of Human Cord Blood Mononuclear Cells in a Three-Dimensional Scaffold.
Mortera-Blanco T; Mantalaris A; Bismarck A; Panoskaltsis N
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Alla övriga publikationer

Preprint: BIORXIV. 2023
Erythroid differentiation intensifies RNA mis-splicing inSF3B1-mutant myelodysplastic syndromes with ring sideroblasts
Moura P; Mortera-Blanco T; Hofman IJF; Todisco G; Kretzschmar W; Björklund A-C; Creignou M; Hagemann-Jensen M; Ziegenhain C; Granados D; Barbosa I; Walldin G; Jansson M; Ashley N; Mead A; Lundin V; Dimitriou M; Yoshizato T; Woll P; Ogawa S; Sandberg R; Jacobsen SE; Hellström-Lindberg E
Conference publication: BLOOD. 2022;140:6898-6899
Long-Term Clonal Inversion in an MDS-RS Case with Dual SF3B1 Mutations
Moura PL; Hofman IJF; Nannya Y; Aliouat A; Mortera-Blanco T; Yoshizato T; Saiki R; Nakagawa MM; Bjorklund A-C; Walldin G; Barbosa I; Jansson M; Grasso F; Creignou M; Elvarsdottir EM; Woll PS; Jacobsen SEW; Ogawa S; Hellstrom-Lindberg E
Meeting abstract: BLOOD. 2022;140:6968-6970
Transfusion Patterns during Early Follow-up Predict Overall Survival Independently of IPSS-M in Patients with Myelodysplastic Syndromes
Creignou M; Bernard E; Crowther M; Tranberg A; Ejerblad E; Nilsson L; Garelius H; Antunovic P; Rasmussen BEH; Lorenz F; Todisco G; Walldin G; Mortera-Blanco T; Jansson M; Tobiasson M; Edgren G; Jadersten M; Papaemmanuil E; Hellstrom-Lindberg E
Letter: BLOOD ADVANCES. 2022;6(16):4705-4709
The extent of residual WT HSPCs is associated with the degree of anemia in patients with SF3B1-mutated MDS-RS
Hofman IJF; Mortera-Blanco T; Moura PL; Vestlund J; Larsson SV; Elvarsdottir EM; Walldin G; Tobiasson M; Sander B; Dimitriou M; Jacobsen S-EW; Woll PS; Jadersten M; Hellstrom-Lindberg E
Meeting abstract: BLOOD. 2021;138:147
Isogenic MDS-RS Patient-Derived iPSCs Define the Mis-Spliced Transcript Repertoire and Chromatin Landscape of SF3B1-Mutant Hematopoietic Stem/Progenitor Cells
Simomitis GA; Deslauriers AG; Kotini AG; Bernard E; Esposito D; Olszewska M; Spyrou N; Ossa JA; Mortera-Blanco T; Koche R; Aaronson S; Hellstrom-Lindberg E; Papaemmanuil E; Papapetrou EP
Meeting abstract: BLOOD. 2021;138:3695
Whole Transcriptome Analysis Identifies Distinct Gene Expression Profiles between SF3B1mut and SF3B1 wt Myelodysplastic Syndrome with Ring Sideroblasts
Todisco G; Creignou M; Bernard E; Björklund A-C; Moura PL; Jansson M; Chang D; Venckute S; Walldin G; Malcovati L; Tesi B; Mortera-Blanco T; Barbosa I; Papaemmanuil E; Lindberg EH
Conference publication: LEUKEMIA RESEARCH. 2021;108:S10-S11
WHOLE TRANSCRIPTOME ANALYSIS IDENTIFIES DISTINCT GENE EXPRESSION PROFILES BETWEEN SF3B1MUT AND SF3B1WT MYELODYSPLASTIC SYNDROME WITH RING SIDEROBLASTS
Todisco G; Creignou M; Bernard E; Bjorklund A-C; Moura P; Jansson M; Barbosa I; Chang D; Venckute S; Walldin G; Tesi B; Mortera-Blanco T; Papaemmanuil E; Hellstrom-Lindberg E
Conference publication: BLOOD. 2019;134:2993
Identification of an Expanded Immature Cell Population in Human Bone Marrow during Erythroid Responses to ESA Treatment
Hofman IJF; Mortera-Blanco T; Larsson SV; Jacobsen SEW; Woll PS; Dimitriou M; Lindberg EH
Review: WORLD JOURNAL OF STEM CELLS. 2019;11(8):476-490
Bone marrow microenvironment: The guardian of leukemia stem cells
Houshmand M; Blanco TM; Circosta P; Yazdi N; Kazemi A; Saglio G; Zarif MN
Conference publication: HAEMATOLOGICA. 2016;101:159
SF3B1 MUTATIONS IN MDS-RS ARISE IN MULTIPOTENT HEMOPOETIC STEM CELLS
Mortera-Blanco T; Dimitriou M; Woll PS; Elvarsdottir E; Karimi M; Conte S; Jansson M; Douagi I; Papaemmanuil E; Jacobsen SE; Hellstrom-Lindberg E
Conference publication: HAEMATOLOGICA. 2016;101:69
A CULTURE MODEL MIMICKING THE BM-NICHE ALLOWS FOR STUDYING THE DYSREGULATED ERYTHROPOIESIS OF SF3B1 MUTATED MYELODYSPLASTIC SYNDROME WITH RINGED SIDEROBLASTS
Elvarsdottir EM; Mortera-Blanco T; Dimitriou M; Conte S; Sander B; Jansson M; Douagi I; Jacobsen SE; Hellstrom-Lindberg E
Book chapter: COMPREHENSIVE BIOTECHNOLOGY. 2016;p. 225-235
5.17 Tissue Engineering of Normal and Abnormal Bone Marrow☆
Mortera-Blanco T; Rende M; Panoskaltsis N; Mantalaris A
Conference publication: LEUKEMIA RESEARCH. 2015;39:S36
CHARACTERIZATION OF THE HEMATOPOIETIC STEM AND PROGENITOR CELL HIERARCHY IN MYELODYSPLASTIC SYNDROMES PATIENTS WITH MONOSOMY 7 AS THE SOLE CYTOGENETIC ABNORMALITY
Dimitriou M; Mortera-Blanco T; Woll PS; Karimi M; Doolittle H; Wedge DC; Papaemmanuil E; Jacobsen SE; Hellstrom-Lindberg E
Corrigendum: CANCER CELL. 2015;27(4):603-605
Myelodysplastic Syndromes Are Propagated by Rare and Distinct Human Cancer Stem Cells In Vivo (vol 25, pg 794, 2014)
Woll PS; Kjaellquist U; Chowdhury O; Doolittle H; Wedge DC; Thongjuea S; Erlandsson R; Ngara M; Anderson K; Deng Q; Mead AJ; Stenson L; Giustacchini A; Duarte S; Giannoulatou E; Taylor S; Karimi M; Scharenberg C; Mortera-Blanco T; Macaulay IC; Clark S-A; Dybedal I; Josefsen D; Fenaux P; Hokland P; Holm MS; Cazzola M; Malcovati L; Tauro S; Bowen D; Boultwood J; Pellagatti A; Pimanda JE; Unnikrishnan A; Vyas P; Goehring G; Schlegelberger B; Tobiasson M; Kvalheim G; Constantinescu SN; Nerlov C; Nilsson L; Campbell PJ; Sandberg R; Papaemmanuil E; Hellstroem-Lindberg E; Linnarsson S; Jacobsen SEW
Conference publication: BLOOD. 2014;124(21):3490
Characterization of the Hematopoietic Stem and Progenitor Cell Hierarchy in Myelodysplastic Syndromes Patients with Monosomy 7 As the Sole Cytogenetic Abnormality
Dimitriou M; Mortera-Blanco T; Woll PS; Karimi M; Doolittle H; Jacobsen SEW; Hellstrom-Lindberg E
Corrigendum: CANCER CELL. 2014;25(6):861
Myelodysplastic Syndromes Are Propagated by Rare and Distinct Human Cancer Stem Cells In Vivo (vol 25, pg 794, 2014)
Woll PS; Kjaellquist U; Chowdhury O; Doolittle H; Wedge DC; Thongjuea S; Erlandsson R; Ngara M; Anderson K; Deng Q; Mead AJ; Stenson L; Giustacchini A; Duarte S; Giannoulatou E; Taylor S; Karimi M; Scharenberg C; Mortera-Blanco T; Macaulay IC; Clark S-A; Dybedal I; Josefsen D; Fenaux P; Hokland P; Holm MS; Cazzola M; Malcovati L; Tauro S; Bowen D; Boultwood J; Pellagatti A; Pimanda JE; Unnikrishnan A; Vyas P; Goehring G; Schlegelberger B; Tobiasson M; Kvalheim G; Constantinescu SN; Nerlov C; Nilsson L; Campbell PJ; Sandberg R; Papaemmanuil E; Hellstroem-Lindberg E; Linnarsson S; Jacobsen SEW
Meeting abstract: BLOOD. 2013;122(21):2408
Erythropoiesis In SF3B1 Mutated RARS Is Disrupted During Terminal Erythroid Maturation
Conte S; Vesterlund L; Katayama S; Karimi M; Papaemmanuil E; Jansson M; Mortera-Blanco T; Dimitriou M; Sander B; Skoog T; Campbell PJ; Kere J; Unneberg P; Hellstroem-Lindberg E
Meeting abstract: LEUKEMIA RESEARCH. 2013;37:S24-S25
Aberrant splicing during erythroid differentiation in SF3B1 mutated sideroblastic anemia
Conte S; Vesterlund L; Katayama S; Karimi M; Unneberg P; Papaemmanuil E; Jansson M; Mortera-Blanco T; Dimitriou M; Sander B; Skoog T; Campbell P; Kere J; Hellstrom-Lindberg E
Conference publication: HAEMATOLOGICA. 2013;98:73-74
ABERRANT SPLICING DURING ERYTHROID DIFFERENTIATION IN SF3B1 MUTATED SIDEROBLASTIC
Conte S; Vesterlund L; Katayama S; Karimi M; Unneberg P; Papaemmanuil E; Jansson M; Mortera-Blanco T; Dimitriou M; Sander B; Skoog T; Campbells P; Kere J; Hellstrom-Lindberg E
Meeting abstract: BLOOD. 2012;120(21):276
Physiologic Erythropoiesis with Enhanced Globin Switching and Endogenous Cytokine Production in a Long-Term Serum-free in Vitro human Bone Marrow Biomimicry
Rende M; Fauzi I; Mortera-Blanco T; da Costa Medeiros JM; Mantalaris A; Panoskaltsis N
Book chapter: COMPREHENSIVE BIOTECHNOLOGY. 2011;p. 331-340
5.26 Tissue Engineering of Normal and Abnormal Bone Marrow
Mortera-Blanco T; Panoskaltsis N; Mantalaris A
Review: JOURNAL OF THE ROYAL SOCIETY INTERFACE. 2009;6(32):209-232
Stem cell bioprocessing: fundamentals and principles
Placzek MR; Chung I-M; Macedo HM; Ismail S; Blanco TM; Lim M; Cha JM; Fauzi I; Kang Y; Yeo DCL; Ma CYJ; Polak JM; Panoskaltsis N; Mantalaris A
Conference publication: BLOOD. 2009;114(22):208
Long-Term in Vitro Cytokine-Free and Serum-Free Culture of Human Cord Blood Mononuclear Cells in a Three-Dimensional Scaffold
Mortera-Blanco T; Mantalaris A; Bismarck A; Panoskaltsis N
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Anställningar

Senior Forskningsspecialist, Medicin, Huddinge, Karolinska Institutet, 2022-
Senior Forskningsspecialist, Medicinsk epidemiologi och biostatistik, Karolinska Institutet, 2024-2025

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