Stephen Malin

Publikationer
Forskningsbidrag
CV
Populärvetenskap och samverkan

Artiklar

Journal article: NAT CARDIOVASC RES. 2024;3(3):356-371

Kupffer cells dictate hepatic responses to the atherogenic dyslipidemic insult

Di Nunzio G; Hellberg S; Zhang Y; Ahmed O; Wang J; Zhang X; Bjoerck HM; Chizh V; Schipper R; Aulin H; Francis R; Fagerberg L; Gistera A; Metso J; Manfe V; Franco-Cereceda A; Eriksson P; Jauhiainen M; Hagberg CE; Olofsson PS; Malin SG
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2023;120(14):e2212476120

Cholinergic regulation of vascular endothelial function by human ChAT⁺ T cells

Tarnawski L; Shavva VS; Kort EJ; Zhuge Z; Nilsson I; Gallina AL; Martinez-Enguita D; Sahlgren BH; Weiland M; Caravaca AS; Schmidt S; Chen P; Abbas K; Wang F-H; Ahmed O; Eberhardson M; Farnert A; Weitzberg E; Gustafsson M; Kehr J; Malin SG; Hult H; Carlstrom M; Jovinge S; Olofsson PS
Article: REDOX BIOLOGY. 2022;56:102422

NCF4 dependent intracellular reactive oxygen species regulate plasma cell formation

He C; Luo H; Coelho A; Liu M; Li Q; Xu J; Kra A; Malin S; Yuan Z; Holmdahl R
Article: CIRCULATION RESEARCH. 2022;130(12):1869-1887

Animal Models of Atherosclerosis-Supportive Notes and Tricks of the Trade

Gistera A; Ketelhuth DFJ; Malin SG; Hansson GK
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2022;119(22):e2023285119

Vagus nerve stimulation promotes resolution of inflammation by a mechanism that involves Alox15 and requires the α7nAChR subunit

Caravaca AS; Gallina AL; Tarnawski L; Shavva VS; Colas RA; Dalli J; Malin SG; Hult H; Arnardottir H; Olofsson PS
Article: EMBO JOURNAL. 2022;41(7):e108397

The PAX5-JAK2 translocation acts as dual-hit mutation that promotes aggressive B-cell leukemia via nuclear STAT5 activation

Jurado S; Fedl AS; Jaritz M; Kostanova-Poliakova D; Malin SG; Mullighan CG; Strehl S; Fischer M; Busslinger M
Journal article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2021;41(Suppl_1)

Abstract 101: B1b Cell Homeostasis Is Maintained By Cd40 In Atherosclerosis

Reiche ME; Pattarabajinard O; Upadhye A; Poels K; van Tiel C; Malin SG; Binder CJ; Gerdes N; Weber C; Atzler D; McNamara CA; Lutgens E
Article: SCIENCE IMMUNOLOGY. 2021;6(61):eabg5003

Pax5 regulates B cell immunity by promoting PI3K signaling via PTEN down-regulation

Calderon L; Schindler K; Malin SG; Schebesta A; Sun Q; Schwickert T; Alberti C; Fischer M; Jaritz M; Tagoh H; Ebert A; Minnich M; Liston A; Cochella L; Busslinger M
Article: FRONTIERS IN CARDIOVASCULAR MEDICINE. 2021;8:655869

AMPA-Type Glutamate Receptors Associated With Vascular Smooth Muscle Cell Subpopulations in Atherosclerosis and Vascular Injury

Gallina AL; Rykaczewska U; Wirka RC; Caravaca AS; Shavva VS; Youness M; Karadimou G; Lengquist M; Razuvaev A; Paulsson-Berne G; Quertermous T; Gistera A; Malin SG; Tarnawski L; Matic L; Olofsson PS
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2020;217(11):e20200147

Repression of the B cell identity factor Pax5 is not required for plasma cell development.

Liu GJ; Jaritz M; Wöhner M; Agerer B; Bergthaler A; Malin SG; Busslinger M
Article: JOURNAL OF INTERNAL MEDICINE. 2020;288(3):321-334

Treatment with a Toll-like Receptor 7 ligand evokes protective immunity against atherosclerosis in hypercholesterolaemic mice

Karadimou G; Gistera A; Gallina AL; Caravaca AS; Centa M; Salagianni M; Andreakos E; Hansson GK; Malin S; Olofsson PS; Paulsson-Berne G
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2020;117(16):9054-9063

Combined proinflammatory cytokine and cognate activation of invariant natural killer T cells enhances anti-DNA antibody responses

Sedimbi SK; Hagglof T; Garimella MG; Wang S; Duhlin A; Coelho A; Ingelshed K; Mondoc E; Malin SG; Holmdahl R; Lane DP; Leadbetter EA; Karlsson MCI
Journal article: JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. 2019;(148)

Quantification of Atherosclerosis in Mice

Centa M; Ketelhuth DFJ; Malin S; Gisterå A
Article: JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. 2019;(148)

Quantification of Atherosclerosis in Mice

Centa M; Ketelhuth DFJ; Malin S; Gistera A
Article: CIRCULATION. 2019;139(21):2466-2482

Germinal Center-Derived Antibodies Promote Atherosclerosis Plaque Size and Stability

Centa M; Jin H; Hofste L; Hellberg S; Busch A; Baumgartner R; Verzaal NJ; Enoksson SL; Matic LP; Boddul SV; Atzler D; Li DY; Sun C; Hansson GK; Ketelhuth DFJ; Hedin U; Wermeling F; Lutgens E; Binder CJ; Maegdesfessel L; Malin SG
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2018;38(8):e145-e158

Acute Loss of Apolipoprotein E Triggers an Autoimmune Response That Accelerates Atherosclerosis

Centa M; Prokopec KE; Garimella MG; Habir K; Hofste L; Stark JM; Dahdah A; Tibbitt CA; Polyzos KA; Gistera A; Johansson DK; Maeda NN; Hansson GK; Ketelhuth DFJ; Coquet JM; Binder CJ; Karlsson MCI; Malin S
Article: ARTHRITIS & RHEUMATOLOGY. 2018;70(2):193-203

Germinal Center B Cells Are Essential for Collagen-Induced Arthritis

Dahdah A; Habir K; Nandakumar KS; Saxena A; Xu B; Holmdahl R; Malin S
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2016;36(1):25-36

Atherosclerosis Susceptibility in Mice Is Independent of the V1 Immunoglobulin Heavy Chain Gene

Centa M; Gruber S; Nilsson D; Polyzos KA; Johansson DK; Hansson GK; Ketelhuth DFJ; Binder CJ; Malin S
Article: ENDOCRINOLOGY. 2015;156(4):1228-1236

Androgens Regulate Bone Marrow B Lymphopoiesis in Male Mice by Targeting Osteoblast-Lineage Cells

Wilhelmson AS; Stubelius A; Borjesson AE; Wu J; Stern A; Malin S; Martensson I-L; Ohlsson C; Carlsten H; Tivesten A
Article: JOURNAL OF IMMUNOLOGY. 2013;191(7):3753-3763

Expression of the Immune Regulator Tripartite-Motif 21 Is Controlled by IFN Regulatory Factors

Sjostrand M; Ambrosi A; Brauner S; Sullivan J; Malin S; Kuchroo VK; Espinosa A; Wahren-Herlenius M
Article: NATURE IMMUNOLOGY. 2010;11(2):171-179

Role of STAT5 in controlling cell survival and immunoglobulin gene recombination during pro-B cell development.

Malin S; McManus S; Cobaleda C; Novatchkova M; Delogu A; Bouillet P; Strasser A; Busslinger M
Article: GENES & DEVELOPMENT. 2008;22(15):2048-2061

A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse.

Schotta G; Sengupta R; Kubicek S; Malin S; Kauer M; Callén E; Celeste A; Pagani M; Opravil S; De La Rosa-Velazquez IA; Espejo A; Bedford MT; Nussenzweig A; Busslinger M; Jenuwein T
Article: IMMUNITY. 2008;28(6):751-762

Instructive role of the transcription factor E2A in early B lymphopoiesis and germinal center B cell development.

Kwon K; Hutter C; Sun Q; Bilic I; Cobaleda C; Malin S; Busslinger M
Article: NUCLEIC ACIDS RESEARCH. 2005;33(14):4618-4625

DNA-dependent conversion of Oct-1 and Oct-2 into transcriptional repressors by Groucho/TLE

Malin S; Linderson Y; Almqvist J; Ernberg I; Tallone T; Pettersson S
Article: EMBO REPORTS. 2004;5(3):291-296

Corecruitment of the Grg4 repressor by PU.1 is critical for Pax5-mediated repression of B-cell-specific genes

Linderson Y; Eberhard D; Malin S; Johansson A; Busslinger M; Pettersson S
Article: INTERNATIONAL JOURNAL OF CANCER. 2003;103(6):723-729

Expression of the coxsackie and adenovirus receptor in human astrocytic tumors and xenografts

Fuxe J; Liu L; Malin S; Philipson L; Collins VP; Pettersson RF
Article: EMBO JOURNAL. 2002;21(19):5079-5087

Retardation of post-natal development caused by a negatively acting thyroid hormone receptor α1

Tinnikov A; Nordström K; Thorén P; Kindblom JM; Malin S; Rozell B; Adams M; Rajanayagam O; Pettersson S; Ohlsson C; Chatterjee K; Vennström B
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2001;98(14):7910-7915

A mouse model for adenovirus gene delivery

Tallone T; Malin S; Samuelsson A; Wilbertz J; Miyahara M; Okamoto K; Poellinger L; Philipson L; Pettersson S
Visa fler

Alla övriga publikationer

Review: FRONTIERS IN CARDIOVASCULAR MEDICINE. 2022;9:864602

The Spectrum of B Cell Functions in Atherosclerotic Cardiovascular Disease

Smeets D; Gistera A; Malin SG; Tsiantoulas D
Preprint: BIORXIV. 2021

Identification and Characterization of Human Activation-Induced ChAT+CD4+ T Cells

Tarnawski L; Gallina A; Kort E; Shavva V; Zhuge Z; Martínez-Enguita D; Weiland M; Caravaca A; Schmidt S; Wang F; Färnert A; Weitzberg E; Gustafsson M; Eberhardson M; Hult H; Kehr J; Malin S; Carlström M; Jovinge S; Olofsson P
Conference publication: EUROPEAN HEART JOURNAL. 2020;41:3832

Treating ApoE-/- mice with Toll-like receptor 7 ligand lead to expansion of marginal zone B cells, reduced plasma cholesterol and decreased atherosclerosis

Paulsson-Berne G; Karadimou G; Gistera A; Gallina A; Centa M; Salagianni M; Andreakos E; Hansson GK; Malin S; Olofsson P
Preprint: BIORXIV. 2020

Alternate models of acute dyslipidemia reveal divergent pathways upon atherosclerosis initiation

Hellberg S; Shavva VS; Metso J; Chen G; Li Q-Z; Manfè V; Olofsson PS; Jauhiainen M; Binder CJ; Malin SG
Review: CURRENT OPINION IN NEUROBIOLOGY. 2020;62:115-121

Functions of acetylcholine-producing lymphocytes in immunobiology

Malin SG; Shavva VS; Tarnawski L; Olofsson PS
Book chapter: ENCYCLOPEDIA OF CARDIOVASCULAR RESEARCH AND MEDICINE. 2018;p. 68-76

Immune-Mediated Mechanisms of Atherosclerosis

Bäck M; Ketelhuth DFJ; Malin S; Olofsson PS; Paulsson-Berne G; Yan Z-Q; Hansson GK
Book chapter: REFERENCE MODULE IN BIOMEDICAL SCIENCES. 2018;p.

Immune-Mediated Mechanisms of Atherosclerosis

Bäck M; Ketelhuth DFJ; Malin S; Olofsson PS; Paulsson-Berne G; Yan Z-Q; Hansson GK
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):282

Antibodies promote vascular smooth muscle cell proliferation and atherosclerotic plaque stability

Centa M; Jin H; Matic LP; Baumgartner R; Li Y; Boddul SV; Sun C; Hansson GK; Ketelhuth DFJ; Hedin U; Wermeling F; Binder CJ; Maegdesfessel L; Malin S
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):271-272

Antibodies promote vascular smooth muscle cell proliferation and atherosclerotic plaque stability

Centa M; Jin H; Matic LP; Baumgartner R; Li Y; Boddul SV; Sun C; Hansson GK; Ketelhuth DFJ; Hedin U; Wermeling F; Binder CJ; Maegdesfessel L; Malin S
Conference publication: IMMUNOLOGY. 2012;137:31-32

Expression of the immune regulator TRIM21 is controlled by interferon regulatory factors

Sjostrand M; Ambrosi A; Sullivan J; Malin S; Kuchroo VK; Espinosa A; Wahren-Herlenius M
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2012;76(2):210

Expression of the Immune Regulator TRIM21 is Controlled by Interferon Regulatory Factors

Sjostrand M; Ambrosi A; Sullivan J; Malin S; Kuchroo VK; Espinosa A; Wahren-Herlenius M
Review: CURRENT OPINION IN IMMUNOLOGY. 2010;22(2):168-176

STAT5 in B cell development and leukemia.

Malin S; McManus S; Busslinger M
Conference publication: ANTICANCER RESEARCH. 2004;24(5D):3462

AN RNAi KNOCK-OUT AND GENETIC RECONSTITUTION SYSTEM TO RESTORE wt p53 FUNCTION IN CANCER

D'Amato M; Greicius G; Malin S; Pettersson S

Forskningsbidrag

The ‘Dyslipidemic insult’ – an inflammatory response to excess lipoproteins.

Swedish Research Council

1 January 2024 - 31 December 2027
Neural control of inflammation for treatment of cardiovascular disease

Swedish Heart-Lung Foundation

1 January 2023 - 31 December 2025
The immune response to dyslipidemia - Characterization and intervention

Swedish Research Council

1 January 2021 - 31 December 2023
B cells in Cardiovascular Disease

Fondation Leducq

1 January 2020
The interplay between dyslipidemia and inflammation in atherosclerotic plaque initiation and regression

Swedish Heart-Lung Foundation

1 January 2020 - 31 December 2021
The interplay between dyslipidemia and inflammation in atherosclerotic plaque initiation and regression

Swedish Heart-Lung Foundation

1 January 2020 - 31 December 2021
Genome wide approaches to understanding lymphocyte survival

Swedish Research Council

1 January 2012 - 31 December 2014

Anställningar

Senior Forskare, Medicin, Solna, Karolinska Institutet, 2022-

Examina och utbildning

Docent, Immunologi, Karolinska Institutet, 2020
MEDICINE DOKTORSEXAMEN, Institutionen för mikrobiologi, tumör- och cellbiologi, Karolinska Institutet, 2004

Artiklar

Alla övriga publikationer

Forskningsbidrag

Anställningar

Examina och utbildning

Nyheter från KI

Kalenderhändelser från KI