Staffan Strömblad

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Journal article: CELL COMMUNICATION AND SIGNALING. 2025;23(1):269
Matrix stiffness-induced IKBKE and MAPK8 signaling drives a phenotypic switch from DCIS to invasive breast cancer
Yan F; Goransson S; Olofsson H; Vogiatzakis C; Acharekar A; Stromblad S
Article: BREAST CANCER RESEARCH. 2024;26(1):163
Low-dose tamoxifen treatment reduces collagen organisation indicative of tissue stiffness in the normal breast: results from the KARISMA randomised controlled trial
Goeransson S; Hernandez-Varas P; Hammarstrom M; Hellgren R; Backlund M; Lang K; Rosendahl AH; Eriksson M; Borgquist S; Stromblad S; Czene K; Hall P; Gabrielson M
Article: CURRENT OPINION IN CELL BIOLOGY. 2024;86:102304
Regulation of protein synthesis and stability by mechanical cues and its implications in cancer
Goransson S; Stromblad S
Article: JOURNAL OF CLINICAL INVESTIGATION. 2023;133(20):e169671
Antioxidants stimulate BACH1-dependent tumor angiogenesis
Wang T; Dong Y; Huang Z; Zhang G; Zhao Y; Yao H; Hu J; Tueksammel E; Cai H; Liang N; Xu X; Yang X; Schmidt S; Qiao X; Schlisio S; Stromblad S; Qian H; Jiang C; Treuter E; Bergo MO
Article: MOLECULAR SYSTEMS BIOLOGY. 2023;19(6):e11490
Multisite assessment of reproducibility in high-content cell migration imaging data
Hu J; Serra-Picamal X; Bakker G-J; Van Troys M; Winograd-Katz S; Ege N; Gong X; Didan Y; Grosheva I; Polansky O; Bakkali K; Van Hamme E; van Erp M; Vullings M; Weiss F; Clucas J; Dowbaj AM; Sahai E; Ampe C; Geiger B; Friedl P; Bottai M; Stromblad S
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2023;654:73-79
An extracellular matrix stiffness-induced breast cancer cell transcriptome resembles the transition from ductal carcinoma in situ (DCIS) to invasive ductal carcinoma (IDC)
Goransson S; Chen S; Olofsson H; Larsson O; Stromblad S
Article: SCIENCE ADVANCES. 2022;8(12):eabl3667
Local temporal Rac1-GTP nadirs and peaks restrict cell protrusions and retractions
Hu J; Gong X; Stromblad S
Article: INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY. 2021;138:106041
Why is PAK4 overexpressed in cancer?
Costa TDF; Stromblad S
Article: ELIFE. 2021;10:e63284
A small-molecule ICMT inhibitor delays senescence of Hutchinson-Gilford progeria syndrome cells
Chen X; Yao H; Kashif M; Revechon G; Eriksson M; Hu J; Wang T; Liu Y; Tuksammel E; Stromblad S; Ahearn IM; Philips MR; Wiel C; Ibrahim MX; Bergo MO
Article: MOLECULAR & CELLULAR ONCOLOGY. 2020;7(2):1684129
New control of the senescence barrier in breast cancer
Costa TDF; Stromblad S
Article: SCIENTIFIC REPORTS. 2019;9(1):14436
Normal mammary gland development after MMTV-Cre mediated conditional PAK4 gene depletion
Rabieifar P; Zhuang T; Costa TDF; Zhao M; Stromblad S
Article: NATURE COMMUNICATIONS. 2019;10(1):3589
PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer
Costa TDF; Zhuang T; Lorent J; Turco E; Olofsson H; Masia-Balague M; Zhao M; Rabieifar P; Robertson N; Kuiper R; Sjolund J; Spiess M; Hernandez-Varas P; Rabenhorst U; Roswall P; Ma R; Gong X; Hartman J; Pietras K; Adams PD; Defilippi P; Stromblad S
Article: JOURNAL OF CELL BIOLOGY. 2019;218(7):2086-2095
Clathrin-containing adhesion complexes
Lock JG; Baschieri F; Jones MC; Humphries JD; Montagnac G; Stromblad S; Humphries MJ
Article: NATURE CELL BIOLOGY. 2018;20(11):1290-1302
Reticular adhesions are a distinct class of cell-matrix adhesions that mediate attachment during mitosis.
Lock JG; Jones MC; Askari JA; Gong X; Oddone A; Olofsson H; Göransson S; Lakadamyali M; Humphries MJ; Strömblad S
Article: EMBO JOURNAL. 2018;37(17):e98994
KIF13A-regulated RhoB plasma membrane localization governs membrane blebbing and blebby amoeboid cell migration
Gong X; Didan Y; Lock JG; Stromblad S
Journal article: PLOS BIOLOGY. 2018;16(9):e3000030
Correction: WRAP53 Is Essential for Cajal Body Formation and for Targeting the Survival of Motor Neuron Complex to Cajal Bodies.
Mahmoudi S; Henriksson S; Weibrecht I; Smith S; Söderberg O; Strömblad S; Wiman KG; Farnebo M
Article: JOURNAL OF CELL BIOLOGY. 2018;217(6):1929-1940
Active and inactive β1 integrins segregate into distinct nanoclusters in focal adhesions
Spiess M; Hernandez-Varas P; Oddone A; Olofsson H; Blom H; Waithe D; Lock JG; Lakadamyali M; Stromblad S
Article: JOURNAL OF IMMUNOLOGY. 2018;200(5):1790-1801
Inflammation-Sensitive Myosin-X Functionally Supports Leukocyte Extravasation by Cdc42-Mediated ICAM-1-Rich Endothelial Filopodia Formation
Kroon J; Schaefer A; van Rijssel J; Hoogenboezem M; van Alphen F; Hordijk P; Stroes ESG; Stromblad S; van Rheenen J; van Buul JD
Article: METHODS IN MOLECULAR BIOLOGY. 2018;1749:119-134
Using Systems Microscopy to Understand the Emergence of Cell Migration from Cell Organization.
Strömblad S; Lock JG
Article: ONCOTARGET. 2017;8(44):77061-77074
Identification of the PAK4 interactome reveals PAK4 phosphorylation of N-WASP and promotion of Arp2/3-dependent actin polymerization
Zhao M; Spiess M; Johansson HJ; Olofsson H; Hu J; Lehtio J; Stromblad S
Article: SCIENTIFIC REPORTS. 2017;7(1):7031
Pdx1-Cre-driven conditional gene depletion suggests PAK4 as dispensable for mouse pancreas development
Zhao M; Rabieifar P; Costa TDF; Zhuang T; Minden A; Lohr M; Heuchel R; Stromblad S
Article: ONCOGENE. 2016;35(15):1955-1964
RING finger protein 31 promotes p53 degradation in breast cancer cells
Zhu J; Zhao C; Zhuang T; Jonsson P; Sinha I; Williams C; Stromblad S; Dahlman-Wright K
Article: ELIFE. 2016;5:e11384
An analysis toolbox to explore mesenchymal migration heterogeneity reveals adaptive switching between distinct modes
Shafqat-Abbasi H; Kowalewski JM; Kiss A; Gong X; Hernandez-Varas P; Berge U; Jafari-Mamaghani M; Lock JG; Stromblad S
Article: ONCOTARGET. 2015;6(41):43853-43868
p21-activated kinase group II small compound inhibitor GNE-2861 perturbs estrogen receptor alpha signaling and restores tamoxifen-sensitivity in breast cancer cells
Zhuang T; Zhu J; Li Z; Lorent J; Zhao C; Dahlman-Wright K; Stromblad S
Article: INTEGRATIVE BIOLOGY. 2015;7(10):1171-1185
Non-monotonic cellular responses to heterogeneity in talin protein expression-level
Kiss A; Gong X; Kowalewski JM; Shafqat-Abbasi H; Stromblad S; Lock JG
Article: NATURE COMMUNICATIONS. 2015;6:7524
A plastic relationship between vinculin-mediated tension and adhesion complex area defines adhesion size and lifetime
Hernandez-Varas P; Berge U; Lock JG; Stromblad S
Article: PLOS ONE. 2015;10(8):e0135204
Disentangling Membrane Dynamics and Cell Migration; Differential Influences of F-actin and Cell-Matrix Adhesions
Kowalewski JM; Shafqat-Abbasi H; Jafari-Mamaghani M; Ganebo BE; Gong X; Stromblad S; Lock JG
Article: ONCOGENE. 2014;33(34):4340-4351
The atypical ubiquitin ligase RNF31 stabilizes estrogen receptor α and modulates estrogen-stimulated breast cancer cell proliferation
Zhu J; Zhao C; Kharman-Biz A; Zhuang T; Jonsson P; Liang N; Williams C; Lin C-Y; Qiao Y; Zendehdel K; Stroemblad S; Treuter E; Dahlman-Wright K
Article: CELL METABOLISM. 2014;19(6):981-992
Early B Cell Factor 1 Regulates Adipocyte Morphology and Lipolysis in White Adipose Tissue
Gao H; Mejhert N; Fretz JA; Arner E; Lorente-Cebrian S; Ehrlund A; Dahlman-Wright K; Gong X; Stromblad S; Douagi I; Laurencikiene J; Dahlman I; Daub CO; Ryden M; Horowitz MC; Arner P
Article: PLOS ONE. 2014;9(2):e90593
Plasticity in the Macromolecular-Scale Causal Networks of Cell Migration
Lock JG; Mamaghani MJ; Shafqat-Abbasi H; Gong X; Tyrcha J; Stromblad S
Article: FEBS LETTERS. 2013;587(6):631-638
A feedback regulation between Kindlin-2 and GLI1 in prostate cancer cells
Gao J; Khan AA; Shimokawa T; Zhan J; Stromblad S; Fang W; Zhang H
Article: BIOLOGICAL PSYCHIATRY. 2013;73(6):583-590
Molecular Networks of DYX1C1 Gene Show Connection to Neuronal Migration Genes and Cytoskeletal Proteins
Tammimies K; Vitezic M; Matsson H; Le Guyader S; Burglin TR; Ohman T; Stromblad S; Daub CO; Nyman TA; Kere J; Tapia-Paez I
Article: JOURNAL OF CELL SCIENCE. 2012;125(22):5338-5352
Focal adhesion disassembly is regulated by a RIAM to MEK-1 pathway
Colo GP; Hernandez-Varas P; Lock J; Bartolome RA; Arellano-Sanchez N; Stromblad S; Teixido J
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2012;287(35):29336-29347
Protein Kinase Cα (PKCα) Regulates p53 Localization and Melanoma Cell Survival Downstream of Integrin αv in Three-dimensional Collagen and in Vivo
Smith SD; Enge M; Bao W; Thullberg M; Costa TDF; Olofsson H; Gashi B; Selivanova G; Stromblad S
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2011;286(21):18492-18504
Rap1-GTP-interacting Adaptor Molecule (RIAM) Protein Controls Invasion and Growth of Melanoma Cells
Hernandez-Varas P; Colo GP; Bartolome RA; Paterson A; Medrano-Fernandez I; Arellano-Sanchez N; Cabanas C; Sanchez-Mateos P; Lafuente EM; Boussiotis VA; Stromblad S; Teixido J
Article: CELL CYCLE. 2011;10(2):301-307
PRIMA-1^Met/APR-246 induces wild-type p53-dependent suppression of malignant melanoma tumor growth in 3D culture and in vivo
Bao W; Chen M; Zhao X; Kumar R; Spinnler C; Thullberg M; Issaeva N; Selivanova G; Stromblad S
Article: CELLULAR & MOLECULAR BIOLOGY LETTERS. 2011;16(4):638-651
FUNCTIONAL CHARACTERIZATION OF HUMAN KINDLIN-2 CORE PROMOTER IDENTIFIES A KEY ROLE OF SP1 IN KINDLIN-2 TRANSCRIPTIONAL REGULATION
Khan AA; Shimokawa T; Stromblad S; Zhang H
Article: CANCER LETTERS. 2010;299(1):54-62
Kindlin-2 controls sensitivity of prostate cancer cells to cisplatin-induced cell death
Gong X; An Z; Wang Y; Guan L; Fang W; Stromblad S; Jiang Y; Zhang H
Article: PLOS BIOLOGY. 2010;8(11):e1000521
WRAP53 Is Essential for Cajal Body Formation and for Targeting the Survival of Motor Neuron Complex to Cajal Bodies
Mahmoudi S; Henriksson S; Weibrecht I; Smith S; Soderberg O; Stromblad S; Wiman KG; Farnebo M
Article: INTERNATIONAL JOURNAL OF CANCER. 2010;127(9):1999-2008
Kindlin-2 is expressed in malignant mesothelioma and is required for tumor cell adhesion and migration
An Z; Dobra K; Lock JG; Stromblad S; Hjerpe A; Zhang H
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2010;107(43):18622-18627
p21-activated kinase 4 regulates ovarian cancer cell proliferation, migration, and invasion and contributes to poor prognosis in patients
Siu MKY; Chan HY; Kong DSH; Wong ESY; Wong OGW; Ngan HYS; Tam KF; Zhang H; Li Z; Chan QKY; Tsao SW; Stromblad S; Cheung ANY
Article: JOURNAL OF CELL SCIENCE. 2010;123(20):3525-3534
PtdIns(3,4,5)P₃ is a regulator of myosin-X localization and filopodia formation
Plantard L; Arjonen A; Lock JG; Nurani G; Ivaska J; Stromblad S
Article: MOLECULAR BIOLOGY OF THE CELL. 2010;21(19):3317-3329
Integrin-mediated Cell Attachment Induces a PAK4-dependent Feedback Loop Regulating Cell Adhesion through Modified Integrin αvβ5 Clustering and Turnover
Li Z; Lock JG; Olofsson H; Kowalewski JM; Teller S; Liu Y; Zhang H; Stromblad S
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2010;285(31):23699-23710
p21-activated Kinase 4 Phosphorylation of Integrin β5 Ser-759 and Ser-762 Regulates Cell Migration
Li Z; Zhang H; Lundin L; Thullberg M; Liu Y; Wang Y; Claesson-Welsh L; Stromblad S
Article: CELL CYCLE. 2008;7(8):984-988
Anchorage-independent cytokinesis as part of oncogenic transformation?
Thullberg M; Stroemblad S
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2007;104(51):20338-20343
Oncogenic H-Ras V12 promotes anchorage-independent cytokinesis in human fibroblasts
Thullberg M; Gad A; Le Guyader S; Stromblad S
Article: BMC BIOTECHNOLOGY. 2007;7:37
Single fluorescent protein-based Ca²⁺ sensors with increased dynamic range
Souslova EA; Belousov VV; Lock JG; Stromblad S; Kasparov S; Bolshakov AP; Pinelis VG; Labas YA; Lukyanov S; Mayr LM; Chudakov DM
Article: ONCOGENE. 2007;26(12):1820-1828
The kinase-inhibitory domain of p21-activated kinase 1 (PAK1) inhibits cell cycle progression independent of PAK1 kinase activity
Thullberg M; Gad A; Beeser A; Chernoff J; Stromblad S
Journal article: NAN FANG YI KE DA XUE XUE BAO = JOURNAL OF SOUTHERN MEDICAL UNIVERSITY. 2006;26(6):730-733
[Preparation of anti-P21-activated kinase 5 polyclonal antibody and its application in dental germ cells].
An Z-W; Liu H-W; Jia Z-M; Li Z-F; Strömblad S; Zhang H-Q
Article: JOURNAL OF CELL BIOLOGY. 2004;167(4):745-756
Integrin αv-mediated inactivation of p53 controls a MEK1-dependent melanoma cell survival pathway in three-dimensional collagen
Bao WJ; Strömblad S
Article: ONCOGENE. 2004;23(47):7874-7881
Recombinant CD44-HABD is a novel and potent direct angiogenesis inhibitor enforcing endothelial cell-specific growth inhibition independently of hyaluronic acid binding
Päll T; Gad A; Kasak L; Drews M; Strömblad S; Kogerman P
Article: NATURE CELL BIOLOGY. 2004;6(6):523-531
Myosin-X provides a motor-based link between integrins and the cytoskeleton
Zhang HQ; Berg JS; Li ZL; Wang YL; Lång P; Sousa AD; Bhaskar A; Cheney RE; Strömblad S
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2004;279(14):13640-13644
Retinoblastoma susceptibility gene product (pRb) and p107 functionally separate the requirements for serum and anchorage in the cell cycle G₁-phase
Gad A; Thullberg M; Dannenberg JH; Riele HT; Strömblad S
Article: BIOLOGICAL PROCEDURES ONLINE. 2002;4:81-87
Use of an Immobilized Monoclonal Antibody to Examine Integrin alpha5beta1 Signaling Independent of Cell Spreading.
Bao W; Strömblad S
Article: JOURNAL OF CELL BIOLOGY. 2002;158(7):1287-1297
P21-activated kinase 4 interacts with integrin αvβ5 and regulates αvβ5-mediated cell migration
Zhang HQ; Li ZL; Viklund EK; Strömblad S
Article: MOLECULAR AND CELLULAR BIOLOGY. 2002;22(13):4587-4597
Cell attachment to the extracellular matrix induces proteasomal degradation of p21^CIP1 via Cdc42/Rac1 signaling
Bao WJ; Thullberg M; Zhang HQ; Onischenko A; Strömblad S
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2002;277(16):13371-13374
Loss of p53 compensates for α_v-integrin function in retinal neovascularization
Strömblad S; Fotedar A; Brickner H; Theesfeld C; de Diaz EA; Friedlander M; Cheresh DA
Article: NATURE CELL BIOLOGY. 2001;3(2):150-157
RANTES promotes growth and survival of human first-trimester forebrain astrocytes
Bakhiet M; Tjernlund A; Mousa A; Gad A; Strömblad S; Kuziel WA; Seiger A; Andersson J
Article: CANCER RESEARCH. 1999;59(11):2724-2730
Integrin α_Vβ₃ promotes M21 melanoma growth in human skin by regulating tumor cell survival
Petitclerc E; Strömblad S; von Schalscha TL; Mitjans F; Piulats J; Montgomery AMP; Cheresh DA; Brooks PC
Journal article: TRENDS IN CELL BIOLOGY. 1998;8(10):421-422
Branching out in tumour therapy
Strömblad S
Journal article: RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES. 1998;18(5):493
Integrin αvβ3 Requirement for Sustained Mitogen-activated Protein Kinase Activity during Angiogenesis.
Eliceiri BP; Klemke R; Strömblad S; Cheresh DA
Article: JOURNAL OF CELL BIOLOGY. 1998;140(5):1255-1263
Integrinαvβ3 requirement for sustained mitogen-activated protein kinase activity during angiogenesis
Eliceiri BP; Klemke R; Strömblad S; Cheresh DA
Article: TRENDS IN CELL BIOLOGY. 1996;6(12):462-468
Cell adhesion and angiogenesis
Stromblad S; Cheresh DA
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1996;271(46):29393-29399
Requirement of receptor-bound urokinase-type plasminogen activator for integrin alpha v beta 5-directed cell migration
Yebra M; Parry GCN; Stromblad S; Mackman N; Rosenberg S; Mueller BM; Cheresh DA
Article: JOURNAL OF CLINICAL INVESTIGATION. 1996;98(2):426-433
Suppression of p53 activity and p21(WAF1/CIP1) expression by vascular cell integrin alpha v beta 3 during angiogenesis
Stromblad S; Becker JC; Yebra M; Brooks PC; Cheresh DA
Article: CELL. 1996;85(5):683-693
Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3
Brooks PC; Stromblad S; Sanders LC; vonSchalscha TL; Aimes RT; StetlerStevenson WG; Quigley JP; Cheresh DA
Article: JOURNAL OF CLINICAL INVESTIGATION. 1995;96(4):1815-1822
ANTIINTEGRIN ALPHA-V-BETA-3 BLOCKS HUMAN BREAST-CANCER GROWTH AND ANGIOGENESIS IN HUMAN SKIN
BROOKS PC; STROMBLAD S; KLEMKE R; VISSCHER D; SARKAR FH; CHERESH DA
Journal article: MOLECULAR CARCINOGENESIS. 1994;10(2):97-104
INCREASED EXPRESSION OF AND SENSITIVITY TO TRANSFORMING GROWTH-FACTOR-ALPHA - A PROMOTIVE ROLE DURING RAT-LIVER CARCINOGENESIS
STROMBLAD S; ERIKSSON LC; ANDERSSON G
Journal article: EXPERIMENTAL CELL RESEARCH. 1993;204(2):321-328
THE COUPLING BETWEEN TRANSFORMING GROWTH FACTOR-ALPHA AND THE EPIDERMAL GROWTH-FACTOR RECEPTOR DURING RAT-LIVER REGENERATION
STROMBLAD S; ANDERSSON G
Visa fler

Artiklar

Anställningar

Examina och utbildning

Nyheter från KI

Kalenderhändelser från KI